SG10201408162PA - Compositions and methods related to mrna translational enhancer elements - Google Patents

Compositions and methods related to mrna translational enhancer elements

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Publication number
SG10201408162PA
SG10201408162PA SG10201408162PA SG10201408162PA SG10201408162PA SG 10201408162P A SG10201408162P A SG 10201408162PA SG 10201408162P A SG10201408162P A SG 10201408162PA SG 10201408162P A SG10201408162P A SG 10201408162PA SG 10201408162P A SG10201408162P A SG 10201408162PA
Authority
SG
Singapore
Prior art keywords
compositions
enhancer elements
methods related
translational enhancer
mrna translational
Prior art date
Application number
SG10201408162PA
Inventor
Vincent P Mauro
Gerald M Edelman
Wei Zhou
Original Assignee
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Inst filed Critical Scripps Research Inst
Publication of SG10201408162PA publication Critical patent/SG10201408162PA/en

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1051Gene trapping, e.g. exon-, intron-, IRES-, signal sequence-trap cloning, trap vectors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67General methods for enhancing the expression

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  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SG10201408162PA 2007-12-11 2008-12-11 Compositions and methods related to mrna translational enhancer elements SG10201408162PA (en)

Applications Claiming Priority (1)

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US744007P 2007-12-11 2007-12-11

Publications (1)

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SG10201408162PA true SG10201408162PA (en) 2015-01-29

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SG10201408162PA SG10201408162PA (en) 2007-12-11 2008-12-11 Compositions and methods related to mrna translational enhancer elements
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US (2) US8785611B2 (en)
EP (5) EP2610340B1 (en)
JP (3) JP5474816B2 (en)
CN (2) CN101939428B (en)
AU (1) AU2008335723C1 (en)
CA (2) CA2904904A1 (en)
SG (4) SG10201408165WA (en)
WO (1) WO2009075886A1 (en)

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Publication number Publication date
WO2009075886A1 (en) 2009-06-18
CA2708766C (en) 2016-02-02
EP2584038B1 (en) 2014-06-25
SG10201408164XA (en) 2015-01-29
AU2008335723A1 (en) 2009-06-18
CN101939428A (en) 2011-01-05
CA2904904A1 (en) 2009-06-18
EP2610340B1 (en) 2014-10-01
EP2527439B1 (en) 2014-03-26
CA2708766A1 (en) 2009-06-18
EP2610340A1 (en) 2013-07-03
EP2610341A1 (en) 2013-07-03
SG188866A1 (en) 2013-04-30
EP2584038A1 (en) 2013-04-24
SG10201408165WA (en) 2015-01-29
EP2231859A1 (en) 2010-09-29
US20130177581A1 (en) 2013-07-11
JP2016104027A (en) 2016-06-09
JP5873511B2 (en) 2016-03-01
WO2009075886A8 (en) 2010-11-11
AU2008335723B2 (en) 2012-12-13
EP2527439A3 (en) 2012-12-05
EP2231859B1 (en) 2013-01-23
CN101939428B (en) 2014-05-07
JP5474816B2 (en) 2014-04-16
JP2011505831A (en) 2011-03-03
US8785611B2 (en) 2014-07-22
JP2014113163A (en) 2014-06-26
EP2610341B1 (en) 2014-09-17
AU2008335723C1 (en) 2013-05-30
EP2527439A2 (en) 2012-11-28
US20090226470A1 (en) 2009-09-10
CN103911378A (en) 2014-07-09

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