CA2855353C - Revetement de passivation, de protection de ph ou a pouvoir lubrifiant pour conditionnement pharmaceutique, processus et appareil de revetement - Google Patents
Revetement de passivation, de protection de ph ou a pouvoir lubrifiant pour conditionnement pharmaceutique, processus et appareil de revetement Download PDFInfo
- Publication number
- CA2855353C CA2855353C CA2855353A CA2855353A CA2855353C CA 2855353 C CA2855353 C CA 2855353C CA 2855353 A CA2855353 A CA 2855353A CA 2855353 A CA2855353 A CA 2855353A CA 2855353 C CA2855353 C CA 2855353C
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- CA
- Canada
- Prior art keywords
- injection
- solution
- agents
- sodium
- ophthalmic
- Prior art date
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- 238000002161 passivation Methods 0.000 title claims abstract description 198
- 238000000576 coating method Methods 0.000 title claims description 242
- 239000011248 coating agent Substances 0.000 title claims description 215
- 230000001681 protective effect Effects 0.000 title abstract description 9
- 239000011253 protective coating Substances 0.000 claims abstract description 186
- 230000004888 barrier function Effects 0.000 claims abstract description 142
- 239000002243 precursor Substances 0.000 claims abstract description 139
- 239000007789 gas Substances 0.000 claims abstract description 72
- 238000000623 plasma-assisted chemical vapour deposition Methods 0.000 claims abstract description 56
- 239000000758 substrate Substances 0.000 claims abstract description 29
- 239000007924 injection Substances 0.000 claims description 370
- 238000002347 injection Methods 0.000 claims description 370
- 229940090044 injection Drugs 0.000 claims description 366
- 239000000203 mixture Substances 0.000 claims description 73
- 239000012530 fluid Substances 0.000 claims description 63
- 239000000463 material Substances 0.000 claims description 62
- 239000011521 glass Substances 0.000 claims description 52
- -1 Delatestryl Delestrogen Chemical compound 0.000 claims description 45
- 210000004369 blood Anatomy 0.000 claims description 38
- 239000008280 blood Substances 0.000 claims description 38
- 239000000243 solution Substances 0.000 claims description 35
- 239000002131 composite material Substances 0.000 claims description 32
- 229920003023 plastic Polymers 0.000 claims description 26
- 239000004033 plastic Substances 0.000 claims description 26
- 239000003814 drug Substances 0.000 claims description 23
- 239000007788 liquid Substances 0.000 claims description 20
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 19
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 claims description 18
- 229940079593 drug Drugs 0.000 claims description 17
- 229910002808 Si–O–Si Inorganic materials 0.000 claims description 16
- 229940102213 injectable suspension Drugs 0.000 claims description 15
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 15
- 238000005033 Fourier transform infrared spectroscopy Methods 0.000 claims description 14
- 238000001157 Fourier transform infrared spectrum Methods 0.000 claims description 14
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 14
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 claims description 12
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 12
- 238000001990 intravenous administration Methods 0.000 claims description 12
- 239000000047 product Substances 0.000 claims description 12
- 108090001061 Insulin Proteins 0.000 claims description 11
- 102000004877 Insulin Human genes 0.000 claims description 11
- 238000004630 atomic force microscopy Methods 0.000 claims description 11
- 239000003792 electrolyte Substances 0.000 claims description 11
- 230000003746 surface roughness Effects 0.000 claims description 11
- 108010000437 Deamino Arginine Vasopressin Proteins 0.000 claims description 10
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 claims description 10
- 229920000669 heparin Polymers 0.000 claims description 10
- GMVPRGQOIOIIMI-DWKJAMRDSA-N prostaglandin E1 Chemical compound CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O GMVPRGQOIOIIMI-DWKJAMRDSA-N 0.000 claims description 10
- 238000012360 testing method Methods 0.000 claims description 10
- YNDXUCZADRHECN-JNQJZLCISA-N triamcinolone acetonide Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@H]3OC(C)(C)O[C@@]3(C(=O)CO)[C@@]1(C)C[C@@H]2O YNDXUCZADRHECN-JNQJZLCISA-N 0.000 claims description 10
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 9
- 239000008121 dextrose Substances 0.000 claims description 9
- 238000009472 formulation Methods 0.000 claims description 9
- 229940125396 insulin Drugs 0.000 claims description 9
- 229910052708 sodium Inorganic materials 0.000 claims description 9
- 239000011734 sodium Substances 0.000 claims description 9
- XAUDJQYHKZQPEU-KVQBGUIXSA-N 5-aza-2'-deoxycytidine Chemical compound O=C1N=C(N)N=CN1[C@@H]1O[C@H](CO)[C@@H](O)C1 XAUDJQYHKZQPEU-KVQBGUIXSA-N 0.000 claims description 8
- 108010006654 Bleomycin Proteins 0.000 claims description 8
- LIRCDOVJWUGTMW-ZWNOBZJWSA-N Chloramphenicol succinate Chemical compound OC(=O)CCC(=O)OC[C@@H](NC(=O)C(Cl)Cl)[C@H](O)C1=CC=C([N+]([O-])=O)C=C1 LIRCDOVJWUGTMW-ZWNOBZJWSA-N 0.000 claims description 8
- UHDGCWIWMRVCDJ-CCXZUQQUSA-N Cytarabine Chemical compound O=C1N=C(N)C=CN1[C@H]1[C@@H](O)[C@H](O)[C@@H](CO)O1 UHDGCWIWMRVCDJ-CCXZUQQUSA-N 0.000 claims description 8
- 108010060162 alglucerase Proteins 0.000 claims description 8
- RCHHVVGSTHAVPF-ZPHPLDECSA-N apidra Chemical compound C([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@H]1CSSC[C@H]2C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC=3C=CC(O)=CC=3)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=3C=CC(O)=CC=3)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=3C=CC(O)=CC=3)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=3N=CNC=3)NC(=O)[C@H](CO)NC(=O)CNC1=O)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(O)=O)C(=O)N[C@@H](CC(N)=O)C(O)=O)=O)CSSC[C@@H](C(N2)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C(C)C)NC(=O)[C@@H](NC(=O)CN)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](N)CC=1C=CC=CC=1)C(C)C)C1=CNC=N1 RCHHVVGSTHAVPF-ZPHPLDECSA-N 0.000 claims description 8
- CPFJLLXFNPCTDW-BWSPSPBFSA-N benzatropine mesylate Chemical compound CS([O-])(=O)=O.O([C@H]1C[C@H]2CC[C@@H](C1)[NH+]2C)C(C=1C=CC=CC=1)C1=CC=CC=C1 CPFJLLXFNPCTDW-BWSPSPBFSA-N 0.000 claims description 8
- 229960000074 biopharmaceutical Drugs 0.000 claims description 8
- 229960002579 chloramphenicol sodium succinate Drugs 0.000 claims description 8
- 108700033697 corticorelin ovine Proteins 0.000 claims description 8
- LTWQNYPDAUSXBC-CDJGKPBYSA-L dantrolene sodium hemiheptahydrate Chemical compound O.O.O.O.O.O.O.[Na+].[Na+].C1=CC([N+](=O)[O-])=CC=C1C(O1)=CC=C1\C=N\N1C(=O)[N-]C(=O)C1.C1=CC([N+](=O)[O-])=CC=C1C(O1)=CC=C1\C=N\N1C(=O)[N-]C(=O)C1 LTWQNYPDAUSXBC-CDJGKPBYSA-L 0.000 claims description 8
- PIZALBORPSCYJU-QSQMUHTISA-H gadofosveset Chemical compound O.[Na+].[Na+].[Na+].[Gd+3].C1CC(OP([O-])(=O)OC[C@@H](CN(CCN(CC([O-])=O)CC([O-])=O)CC(=O)[O-])N(CC([O-])=O)CC([O-])=O)CCC1(C=1C=CC=CC=1)C1=CC=CC=C1 PIZALBORPSCYJU-QSQMUHTISA-H 0.000 claims description 8
- 108700039926 insulin glulisine Proteins 0.000 claims description 8
- PLBHSZGDDKCEHR-LFYFAGGJSA-N methylprednisolone acetate Chemical compound C([C@@]12C)=CC(=O)C=C1[C@@H](C)C[C@@H]1[C@@H]2[C@@H](O)C[C@]2(C)[C@@](O)(C(=O)COC(C)=O)CC[C@H]21 PLBHSZGDDKCEHR-LFYFAGGJSA-N 0.000 claims description 8
- GRVOTVYEFDAHCL-RTSZDRIGSA-N morphine sulfate pentahydrate Chemical compound O.O.O.O.O.OS(O)(=O)=O.O([C@H]1[C@H](C=C[C@H]23)O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4O.O([C@H]1[C@H](C=C[C@H]23)O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4O GRVOTVYEFDAHCL-RTSZDRIGSA-N 0.000 claims description 8
- QEEJLLNYQOBRRM-KSHGRFHLSA-N ovine crf Chemical compound C([C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1NC=NC=1)NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H]1N(CCC1)C(=O)[C@H]1N(CCC1)C(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)CO)[C@@H](C)CC)[C@@H](C)O)C(C)C)[C@@H](C)O)C1=CN=CN1 QEEJLLNYQOBRRM-KSHGRFHLSA-N 0.000 claims description 8
- 238000002360 preparation method Methods 0.000 claims description 8
- 229920005989 resin Polymers 0.000 claims description 8
- 239000011347 resin Substances 0.000 claims description 8
- DFEYYRMXOJXZRJ-UHFFFAOYSA-N sevoflurane Chemical compound FCOC(C(F)(F)F)C(F)(F)F DFEYYRMXOJXZRJ-UHFFFAOYSA-N 0.000 claims description 8
- PTJRZVJXXNYNLN-UHFFFAOYSA-M sodium;2h-pyrazolo[3,4-d]pyrimidin-1-id-4-one Chemical compound [Na+].[O-]C1=NC=NC2=C1C=NN2 PTJRZVJXXNYNLN-UHFFFAOYSA-M 0.000 claims description 8
- BNHGKKNINBGEQL-UHFFFAOYSA-M sodium;5-ethyl-5-(3-methylbutyl)pyrimidin-3-ide-2,4,6-trione Chemical compound [Na+].CC(C)CCC1(CC)C(=O)NC(=O)[N-]C1=O BNHGKKNINBGEQL-UHFFFAOYSA-M 0.000 claims description 8
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 7
- MQTOSJVFKKJCRP-BICOPXKESA-N azithromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)N(C)C[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 MQTOSJVFKKJCRP-BICOPXKESA-N 0.000 claims description 7
- BMKDZUISNHGIBY-ZETCQYMHSA-N (+)-dexrazoxane Chemical compound C([C@H](C)N1CC(=O)NC(=O)C1)N1CC(=O)NC(=O)C1 BMKDZUISNHGIBY-ZETCQYMHSA-N 0.000 claims description 6
- UCTWMZQNUQWSLP-VIFPVBQESA-N (R)-adrenaline Chemical compound CNC[C@H](O)C1=CC=C(O)C(O)=C1 UCTWMZQNUQWSLP-VIFPVBQESA-N 0.000 claims description 6
- PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 claims description 6
- ZHSKUOZOLHMKEA-UHFFFAOYSA-N 4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid;hydron;chloride Chemical compound Cl.ClCCN(CCCl)C1=CC=C2N(C)C(CCCC(O)=O)=NC2=C1 ZHSKUOZOLHMKEA-UHFFFAOYSA-N 0.000 claims description 6
- KWTQSFXGGICVPE-WCCKRBBISA-N Arginine hydrochloride Chemical compound Cl.OC(=O)[C@@H](N)CCCN=C(N)N KWTQSFXGGICVPE-WCCKRBBISA-N 0.000 claims description 6
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims description 6
- 108010019673 Darbepoetin alfa Proteins 0.000 claims description 6
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 6
- SHWNNYZBHZIQQV-UHFFFAOYSA-J EDTA monocalcium diisodium salt Chemical compound [Na+].[Na+].[Ca+2].[O-]C(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O SHWNNYZBHZIQQV-UHFFFAOYSA-J 0.000 claims description 6
- TZIZWYVVGLXXFV-FLRHRWPCSA-N Triamcinolone hexacetonide Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@H]3OC(C)(C)O[C@@]3(C(=O)COC(=O)CC(C)(C)C)[C@@]1(C)C[C@@H]2O TZIZWYVVGLXXFV-FLRHRWPCSA-N 0.000 claims description 6
- 108010079650 abobotulinumtoxinA Proteins 0.000 claims description 6
- 238000002835 absorbance Methods 0.000 claims description 6
- BMQGVNUXMIRLCK-OAGWZNDDSA-N cabazitaxel Chemical compound O([C@H]1[C@@H]2[C@]3(OC(C)=O)CO[C@@H]3C[C@@H]([C@]2(C(=O)[C@H](OC)C2=C(C)[C@@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C=3C=CC=CC=3)C[C@]1(O)C2(C)C)C)OC)C(=O)C1=CC=CC=C1 BMQGVNUXMIRLCK-OAGWZNDDSA-N 0.000 claims description 6
- 229910052791 calcium Inorganic materials 0.000 claims description 6
- 239000011575 calcium Substances 0.000 claims description 6
- BTYHAFSDANBVMJ-UHFFFAOYSA-N conivaptan hydrochloride Chemical compound Cl.C12=CC=CC=C2C=2NC(C)=NC=2CCN1C(=O)C(C=C1)=CC=C1NC(=O)C1=CC=CC=C1C1=CC=CC=C1 BTYHAFSDANBVMJ-UHFFFAOYSA-N 0.000 claims description 6
- RMRCNWBMXRMIRW-BYFNXCQMSA-M cyanocobalamin Chemical compound N#C[Co+]N([C@]1([H])[C@H](CC(N)=O)[C@]\2(CCC(=O)NC[C@H](C)OP(O)(=O)OC3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)C)C/2=C(C)\C([C@H](C/2(C)C)CCC(N)=O)=N\C\2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O RMRCNWBMXRMIRW-BYFNXCQMSA-M 0.000 claims description 6
- YNKFCNRZZPFMEX-XHPDKPNGSA-N desmopressin acetate trihydrate Chemical compound O.O.O.CC(O)=O.C([C@H]1C(=O)N[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@@H](CSSCCC(=O)N[C@@H](CC=2C=CC(O)=CC=2)C(=O)N1)C(=O)N1[C@@H](CCC1)C(=O)N[C@H](CCCNC(N)=N)C(=O)NCC(N)=O)=O)CCC(=O)N)C1=CC=CC=C1 YNKFCNRZZPFMEX-XHPDKPNGSA-N 0.000 claims description 6
- 229960000605 dexrazoxane Drugs 0.000 claims description 6
- GQPXYJNXTAFDLT-UHFFFAOYSA-L disodium;(2,5-dioxo-4,4-diphenylimidazolidin-1-yl)methyl phosphate Chemical compound [Na+].[Na+].O=C1N(COP([O-])(=O)[O-])C(=O)NC1(C=1C=CC=CC=1)C1=CC=CC=C1 GQPXYJNXTAFDLT-UHFFFAOYSA-L 0.000 claims description 6
- 238000010253 intravenous injection Methods 0.000 claims description 6
- KDXZREBVGAGZHS-UHFFFAOYSA-M methohexital sodium Chemical compound [Na+].CCC#CC(C)C1(CC=C)C(=O)N=C([O-])N(C)C1=O KDXZREBVGAGZHS-UHFFFAOYSA-M 0.000 claims description 6
- CMWTZPSULFXXJA-VIFPVBQESA-N naproxen Chemical compound C1=C([C@H](C)C(O)=O)C=CC2=CC(OC)=CC=C21 CMWTZPSULFXXJA-VIFPVBQESA-N 0.000 claims description 6
- 229960002078 sevoflurane Drugs 0.000 claims description 6
- GMVPRGQOIOIIMI-UHFFFAOYSA-N (8R,11R,12R,13E,15S)-11,15-Dihydroxy-9-oxo-13-prostenoic acid Natural products CCCCCC(O)C=CC1C(O)CC(=O)C1CCCCCCC(O)=O GMVPRGQOIOIIMI-UHFFFAOYSA-N 0.000 claims description 5
- LEBVLXFERQHONN-UHFFFAOYSA-N 1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide Chemical compound CCCCN1CCCCC1C(=O)NC1=C(C)C=CC=C1C LEBVLXFERQHONN-UHFFFAOYSA-N 0.000 claims description 5
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Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D25/00—Details of other kinds or types of rigid or semi-rigid containers
- B65D25/14—Linings or internal coatings
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- C—CHEMISTRY; METALLURGY
- C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
- C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
- C23C16/00—Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes
- C23C16/22—Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes characterised by the deposition of inorganic material, other than metallic material
- C23C16/30—Deposition of compounds, mixtures or solid solutions, e.g. borides, carbides, nitrides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/3129—Syringe barrels
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D25/00—Details of other kinds or types of rigid or semi-rigid containers
- B65D25/02—Internal fittings
- B65D25/04—Partitions
-
- C—CHEMISTRY; METALLURGY
- C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
- C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
- C23C16/00—Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes
- C23C16/04—Coating on selected surface areas, e.g. using masks
- C23C16/045—Coating cavities or hollow spaces, e.g. interior of tubes; Infiltration of porous substrates
-
- C—CHEMISTRY; METALLURGY
- C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
- C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
- C23C16/00—Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes
- C23C16/22—Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes characterised by the deposition of inorganic material, other than metallic material
- C23C16/30—Deposition of compounds, mixtures or solid solutions, e.g. borides, carbides, nitrides
- C23C16/36—Carbonitrides
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- C—CHEMISTRY; METALLURGY
- C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
- C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
- C23C16/00—Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes
- C23C16/22—Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes characterised by the deposition of inorganic material, other than metallic material
- C23C16/30—Deposition of compounds, mixtures or solid solutions, e.g. borides, carbides, nitrides
- C23C16/40—Oxides
- C23C16/401—Oxides containing silicon
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- C—CHEMISTRY; METALLURGY
- C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
- C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
- C23C16/00—Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes
- C23C16/44—Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes characterised by the method of coating
- C23C16/50—Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes characterised by the method of coating using electric discharges
- C23C16/505—Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes characterised by the method of coating using electric discharges using radio frequency discharges
- C23C16/507—Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes characterised by the method of coating using electric discharges using radio frequency discharges using external electrodes, e.g. in tunnel type reactors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M2005/3103—Leak prevention means for distal end of syringes, i.e. syringe end for mounting a needle
- A61M2005/3107—Leak prevention means for distal end of syringes, i.e. syringe end for mounting a needle for needles
- A61M2005/3109—Caps sealing the needle bore by use of, e.g. air-hardening adhesive, elastomer or epoxy resin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/3129—Syringe barrels
- A61M2005/3131—Syringe barrels specially adapted for improving sealing or sliding
Landscapes
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Metallurgy (AREA)
- Organic Chemistry (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Anesthesiology (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- Vascular Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Physics & Mathematics (AREA)
- Plasma & Fusion (AREA)
- Medicinal Preparation (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
La présente invention concerne un procédé permettant de former par PECVD une couche de passivation ou un revêtement de protection de pH sur une surface d'un substrat. Le procédé consiste à former un plasma à partir d'un réactif gazeux contenant des gaz de polymérisation, par exemple un précurseur d'organosilicium et éventuellement de l'O2. Les propriétés de pouvoir lubrifiant, de passivation, de protection de pH, d'hydrophobicité et/ou de barrière de la couche de passivation ou du revêtement de protection de pH sont définies en définissant le rapport entre l'O2 et le précurseur d'organosilicium dans l'alimentation en précurseur et/ou en réglant le courant électrique utilisé pour former le plasma. La présente invention concerne en particulier une couche de passivation et/ou à pouvoir lubrifiant ou un revêtement de protection de pH fabriqués selon ledit procédé.
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
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US201161558885P | 2011-11-11 | 2011-11-11 | |
US61/558,885 | 2011-11-11 | ||
US201261636377P | 2012-04-20 | 2012-04-20 | |
US61/636,377 | 2012-04-20 | ||
US201261645003P | 2012-05-09 | 2012-05-09 | |
US61/645,003 | 2012-05-09 | ||
PCT/US2012/064489 WO2013071138A1 (fr) | 2011-11-11 | 2012-11-09 | Revêtement de passivation, de protection de ph ou à pouvoir lubrifiant pour conditionnement pharmaceutique, processus et appareil de revêtement |
Publications (2)
Publication Number | Publication Date |
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CA2855353A1 CA2855353A1 (fr) | 2013-05-16 |
CA2855353C true CA2855353C (fr) | 2021-01-19 |
Family
ID=48290615
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CA2855353A Active CA2855353C (fr) | 2011-11-11 | 2012-11-09 | Revetement de passivation, de protection de ph ou a pouvoir lubrifiant pour conditionnement pharmaceutique, processus et appareil de revetement |
Country Status (7)
Country | Link |
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US (5) | US10189603B2 (fr) |
EP (1) | EP2776603B1 (fr) |
JP (1) | JP6095678B2 (fr) |
CN (1) | CN103930595A (fr) |
AU (1) | AU2012318242A1 (fr) |
CA (1) | CA2855353C (fr) |
WO (1) | WO2013071138A1 (fr) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
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US11709156B2 (en) | 2017-09-18 | 2023-07-25 | Waters Technologies Corporation | Use of vapor deposition coated flow paths for improved analytical analysis |
US11918936B2 (en) | 2020-01-17 | 2024-03-05 | Waters Technologies Corporation | Performance and dynamic range for oligonucleotide bioanalysis through reduction of non specific binding |
Families Citing this family (83)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2503159C2 (ru) | 2009-02-04 | 2013-12-27 | Дженерал Фьюжен, Инк. | Устройство для сжатия плазмы и способ сжатия плазмы |
MX345403B (es) | 2009-05-13 | 2017-01-30 | Sio2 Medical Products Inc | Revestimiento por pecvd utilizando un precursor organosilícico. |
TWI540132B (zh) | 2009-06-08 | 2016-07-01 | 亞培公司 | Bcl-2族群抑制劑之口服醫藥劑型 |
US9458536B2 (en) | 2009-07-02 | 2016-10-04 | Sio2 Medical Products, Inc. | PECVD coating methods for capped syringes, cartridges and other articles |
US11624115B2 (en) | 2010-05-12 | 2023-04-11 | Sio2 Medical Products, Inc. | Syringe with PECVD lubrication |
UA113500C2 (xx) | 2010-10-29 | 2017-02-10 | Одержані екструзією розплаву тверді дисперсії, що містять індукуючий апоптоз засіб | |
US9878101B2 (en) | 2010-11-12 | 2018-01-30 | Sio2 Medical Products, Inc. | Cyclic olefin polymer vessels and vessel coating methods |
US9272095B2 (en) | 2011-04-01 | 2016-03-01 | Sio2 Medical Products, Inc. | Vessels, contact surfaces, and coating and inspection apparatus and methods |
US11116695B2 (en) | 2011-11-11 | 2021-09-14 | Sio2 Medical Products, Inc. | Blood sample collection tube |
EP2776603B1 (fr) | 2011-11-11 | 2019-03-06 | SiO2 Medical Products, Inc. | Revêtement de passivation, de protection de ph ou à pouvoir lubrifiant pour conditionnement pharmaceutique, processus et appareil de revêtement |
US9155734B2 (en) | 2012-03-07 | 2015-10-13 | Mallinckrodt Llc | Stability of hydromorphone hydrochloride solutions |
CA2887352A1 (fr) | 2012-05-09 | 2013-11-14 | Sio2 Medical Products, Inc. | Enrobage protecteur en saccharide pour conditionnement pharmaceutique |
EP2891389B1 (fr) * | 2012-08-29 | 2017-08-02 | General Fusion Inc. | Appareil d'accélération et de compression de plasma |
FR2994851B1 (fr) * | 2012-09-04 | 2015-08-21 | Rexam Healthcare La Verpillier | Dispositif d'injection de liquide pharmaceutique configure pour etre pre-rempli |
EP2914762B1 (fr) | 2012-11-01 | 2020-05-13 | SiO2 Medical Products, Inc. | Procédé d'inspection de revêtement |
US9903782B2 (en) | 2012-11-16 | 2018-02-27 | Sio2 Medical Products, Inc. | Method and apparatus for detecting rapid barrier coating integrity characteristics |
WO2014085348A2 (fr) | 2012-11-30 | 2014-06-05 | Sio2 Medical Products, Inc. | Contrôle de l'uniformité de dépôt chimique en phase vapeur activé par plasma (pecvd) sur des seringues médicales, des cartouches et analogues |
US9764093B2 (en) | 2012-11-30 | 2017-09-19 | Sio2 Medical Products, Inc. | Controlling the uniformity of PECVD deposition |
US9662450B2 (en) | 2013-03-01 | 2017-05-30 | Sio2 Medical Products, Inc. | Plasma or CVD pre-treatment for lubricated pharmaceutical package, coating process and apparatus |
KR102472240B1 (ko) | 2013-03-11 | 2022-11-30 | 에스아이오2 메디컬 프로덕츠, 인크. | 코팅된 패키징 |
US9937099B2 (en) | 2013-03-11 | 2018-04-10 | Sio2 Medical Products, Inc. | Trilayer coated pharmaceutical packaging with low oxygen transmission rate |
AR095499A1 (es) | 2013-03-14 | 2015-10-21 | Bayer Healthcare Llc | ANTICUERPOS MONOCLONALES CONTRA ANTITROMBINA b |
WO2014144926A1 (fr) | 2013-03-15 | 2014-09-18 | Sio2 Medical Products, Inc. | Procédé de revêtement |
US9952147B2 (en) * | 2013-09-12 | 2018-04-24 | Sio2 Medical Products, Inc. | Rapid, non-destructive, selective infrared spectrometry analysis of organic coatings on molded articles |
US10639421B2 (en) * | 2013-10-15 | 2020-05-05 | Sio2 Medical Products, Inc. | Methods and apparatuses for injection molding walled structures |
US11326254B2 (en) * | 2014-03-03 | 2022-05-10 | Picosun Oy | Protecting an interior of a gas container with an ALD coating |
WO2015136037A1 (fr) * | 2014-03-13 | 2015-09-17 | Stevanato Group International A. S. | Procédé de manipulation d'une formulation de médicament liquide |
US11066745B2 (en) | 2014-03-28 | 2021-07-20 | Sio2 Medical Products, Inc. | Antistatic coatings for plastic vessels |
JP6291318B2 (ja) * | 2014-03-31 | 2018-03-14 | テルモ株式会社 | ロクロニウム臭化物注射液充填プレフィルドシリンジ |
WO2016026040A1 (fr) | 2014-08-19 | 2016-02-25 | General Fusion Inc. | Système et procédé de commande d'un champ magnétique de plasma |
WO2016100557A2 (fr) | 2014-12-17 | 2016-06-23 | Sio2 Medical Products, Inc. | Traitement au plasma avec des composés non polymérisants qui conduit à la réduction de l'adhérence de biomolécules à des articles thermoplastiques |
SG11201705019PA (en) * | 2014-12-23 | 2017-07-28 | Merz Pharma Gmbh & Co Kgaa | Botulinum toxin prefilled container |
WO2016111913A1 (fr) * | 2015-01-05 | 2016-07-14 | Boston Scientific Scimed, Inc. | Microsphère biodégradable éluant un médicament pour le traitement de tumeurs solides |
CN107206175B (zh) * | 2015-02-03 | 2021-06-01 | 莫茨制药有限及两合公司 | 肉毒杆菌毒素预填充式容器 |
BR112017019368B1 (pt) | 2015-03-11 | 2022-08-30 | General Fusion Inc | Câmara de compressão modular |
DE102015207228A1 (de) * | 2015-04-21 | 2016-10-27 | Vetter Pharma-Fertigung GmbH & Co. KG | Primärpackmittel und Verfahren zur Herstellung eines Primärpackmittels |
KR102670650B1 (ko) | 2015-04-30 | 2024-05-31 | 에스아이오2 메디컬 프로덕츠, 인크. | 열가소성 물품으로의 희석 생체분자 부착의 감소를 가져오는 비중합성 화합물을 이용한 플라즈마 처리 |
US11077233B2 (en) | 2015-08-18 | 2021-08-03 | Sio2 Medical Products, Inc. | Pharmaceutical and other packaging with low oxygen transmission rate |
RU2710493C2 (ru) * | 2015-08-24 | 2019-12-26 | Адамис Фармасьютикалз Корпорейшн | Шприцевые устройства |
KR102368081B1 (ko) * | 2015-09-18 | 2022-02-25 | 삼성디스플레이 주식회사 | 유기 발광 표시 장치의 제조방법 및 이를 이용하여 제조된 유기 발광 표시 장치 |
US9978586B2 (en) * | 2015-11-06 | 2018-05-22 | Fei Company | Method of material deposition |
CN108463493B (zh) | 2015-11-16 | 2021-10-15 | Sio2医药产品公司 | 具有拥有降低的生物分子粘附的表面的聚合物衬底以及这种衬底的热塑性制品 |
GB201520483D0 (en) * | 2015-11-20 | 2016-01-06 | Semblant Ltd | Coated Medical devices |
EP3440233A1 (fr) * | 2016-04-08 | 2019-02-13 | Si02 Medical Products, Inc. | Procédé d'application d'une couche de lubrification pecvd avec entrée de gaz mobile |
TWI737742B (zh) * | 2016-06-22 | 2021-09-01 | 德商梅茲製藥有限兩合公司 | 肉毒桿菌毒素的預填充式注射器系統、具有其之套組以及其之使用 |
CN107778350B (zh) * | 2016-08-25 | 2021-04-13 | 成都圣诺生物制药有限公司 | 一种合成罗米地辛的方法 |
AU2017326253B2 (en) | 2016-09-13 | 2021-10-21 | Allergan, Inc. | Stabilized non-protein clostridial toxin compositions |
JP2018052861A (ja) * | 2016-09-29 | 2018-04-05 | ノーベルファーマ株式会社 | ホスフェニトインナトリウム注射剤 |
CN106996891B (zh) * | 2017-05-22 | 2023-06-13 | 上海市第一人民医院 | 一种用于不贴壁细胞免疫染色的染色管及染色方法 |
CN107385411B (zh) * | 2017-06-24 | 2019-03-29 | 淮阴医疗器械有限公司 | 手术缝合针表面的等离子体前处理方法及处理装置 |
WO2019021906A1 (fr) * | 2017-07-24 | 2019-01-31 | 三菱瓦斯化学株式会社 | Cylindre de seringue et seringue |
US10811144B2 (en) | 2017-11-06 | 2020-10-20 | General Fusion Inc. | System and method for plasma generation and compression |
CN108078918B (zh) * | 2017-12-28 | 2020-01-21 | 石药银湖制药有限公司 | 一种提高硫酸特布他林注射液稳定性的处理方法 |
FR3077821B1 (fr) | 2018-02-09 | 2020-12-18 | Coating Plasma Ind | Film de protection a base de silicium pour adhesif, son procede de fabrication et ses utilisations |
SG11202008540WA (en) * | 2018-03-06 | 2020-10-29 | Gore & Ass | Medical delivery devices having low lubricant hydrophobic syringe barrels |
EP3775315A1 (fr) * | 2018-03-27 | 2021-02-17 | SiO2 Medical Products, Inc. | Récipients, contenants et surfaces revêtues de revêtements faisant barrière à l'eau |
CA3100913A1 (fr) | 2018-05-25 | 2019-11-28 | Adamis Pharmaceuticals Corporation | Dispositifs d'urgence |
CN112912123A (zh) * | 2018-10-26 | 2021-06-04 | 贝克顿迪金森法国公司 | 用于医疗注射装置的针罩 |
EP3873569A1 (fr) | 2018-10-29 | 2021-09-08 | SiO2 Medical Products, Inc. | Conditionnements primaires assurant une stabilité améliorée des médicaments protéiques et une réponse immunitaire moins forte |
CN109632934B (zh) * | 2018-12-29 | 2021-10-01 | 上海微谱化工技术服务有限公司 | 一种枸橼酸舒芬太尼与生产系统相容性的分析方法 |
EP3914689A2 (fr) * | 2019-01-25 | 2021-12-01 | SiO2 Medical Products, Inc. | Surfaces de contact communes destinées à être utilisées dans la fabrication, l'emballage, la distribution et l'évaluation de produits biopharmaceutiques |
USD926970S1 (en) * | 2019-02-04 | 2021-08-03 | Portal Instruments, Inc. | Injector cartridge |
CN109771369A (zh) * | 2019-02-28 | 2019-05-21 | 南京济群医药科技股份有限公司 | 一种液体止鼾器及其制备工艺 |
CN110702669A (zh) * | 2019-09-19 | 2020-01-17 | 湖北科益药业股份有限公司 | 一种快速阿昔洛韦凝胶含量测定的方法 |
KR20220110562A (ko) | 2019-12-12 | 2022-08-08 | 노파르티스 아게 | 주입 장치 및 주입 용액 전달 시스템 |
CN113049839B (zh) * | 2019-12-27 | 2022-11-29 | 桂林英美特生物技术研究所 | 一种稳定的肝功能类复合质控品 |
CN111391050B (zh) * | 2020-03-26 | 2021-12-17 | 广州海有生物科技有限公司 | 一种环保防腐剂及其制备方法 |
US20230165946A1 (en) * | 2020-04-08 | 2023-06-01 | Medytox Inc. | Botulinum toxin pre-filled injectable formulation that facilitates discharge rate control and is stable |
CN111760075B (zh) * | 2020-07-08 | 2021-08-13 | 西南交通大学 | 抗菌抗凝血涂层及其制备方法和医用材料 |
CN111929384A (zh) * | 2020-07-31 | 2020-11-13 | 淄博鲁瑞精细化工有限公司 | 利用hs-gc外标法测定有机硅柔软剂中残留甲基硅氧烷含量的方法 |
CN112062833A (zh) * | 2020-10-09 | 2020-12-11 | 国药集团武汉血液制品有限公司 | 一种从血浆组分ⅳ沉淀中提取人血白蛋白的方法 |
CN112552208B (zh) * | 2021-01-25 | 2022-06-10 | 井冈山大学 | 一种用于滴眼液质量检测的荧光分子及其制备和应用 |
CN112871099B (zh) * | 2021-02-03 | 2022-01-11 | 江南大学 | 一种多孔醇溶蛋白微球的制备方法及其产品 |
US11278634B1 (en) | 2021-02-12 | 2022-03-22 | Extrovis Ag | Stable parenteral composition of lacosamide |
CN113041404B (zh) * | 2021-03-19 | 2022-04-05 | 北京化工大学 | 一种基于疏水改性多孔淀粉的具有超声成像能力的医用导管的制备方法及其产品 |
CA3214035A1 (fr) * | 2021-03-31 | 2022-10-06 | Ahmad TAHA | Emballage pharmaceutique depose par depot de couche atomique et seringues et flacons ameliores, par exemple pour des medicaments/vaccins lyophilises/soumis a la chaine du froid |
CN113083039A (zh) * | 2021-04-15 | 2021-07-09 | 中国农业大学 | 一种绿色高效制备玉米秸秆基三醋酸纤维素多孔膜的方法 |
CN113447583A (zh) * | 2021-06-25 | 2021-09-28 | 河北冀安检测服务有限公司 | 一种盐酸氨溴索氯化钠注射液与包材相容性的检测方法 |
US11957178B2 (en) | 2021-11-15 | 2024-04-16 | Apackaging Group Llc | Aerosol actuator |
WO2023172587A1 (fr) * | 2022-03-07 | 2023-09-14 | Opus Life Sciences Llc | Formulations de fluorescéine et kits |
CN115678048B (zh) * | 2022-11-27 | 2024-05-31 | 福州大学 | 一种可促进创面愈合并减少疤痕形成的可注射复合水凝胶及其制备方法和应用 |
CN116855065B (zh) * | 2023-07-05 | 2024-04-05 | 山东雷德新材料有限公司 | 一种低动摩擦系数的密封件及其制备方法 |
CN116617467B (zh) * | 2023-07-20 | 2023-09-19 | 南京医科大学第二附属医院 | 一种抗凝血涂层、管道及其制备方法和应用 |
Family Cites Families (1087)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR891892A (fr) | 1942-11-17 | 1944-03-22 | Aiguille d'injection | |
GB752822A (en) | 1953-03-12 | 1956-07-18 | Onera (Off Nat Aerospatiale) | Improvements in rate of flow meters, especially for liquids |
US3039524A (en) | 1958-11-03 | 1962-06-19 | Du Pont | Filaments having improved crimp characteristics and products containing same |
US3355947A (en) | 1959-02-26 | 1967-12-05 | Rockwell Mfg Co | Viscosity compensated turbine flow meter |
DE1147836B (de) | 1959-09-26 | 1963-04-25 | Nadler Werke | Verfahren zum Sterilisieren von breifoermigen vegetabilischen Nahrungsmitteln |
DE1147838B (de) | 1960-10-12 | 1963-04-25 | Andre Michels | Antrieb der Ecken-Verriegelungsorgane eines Stempels in einer Vorrichtung zum Aufrichten eines Zuschnitts aus Papier, Pappe od. dgl. zu einer Schachtel |
US3274267A (en) | 1963-09-23 | 1966-09-20 | Union Carbide Corp | Cyclic alpha-perfluoro-di-p-xylylenes |
US3297465A (en) | 1963-12-31 | 1967-01-10 | Ibm | Method for producing organic plasma and for depositing polymer films |
US3442686A (en) | 1964-03-13 | 1969-05-06 | Du Pont | Low permeability transparent packaging films |
FR1475825A (fr) | 1966-02-21 | 1967-04-07 | Compteurs Comp D | Perfectionnements aux mesureurs à turbine pour le comptage de volumes de fluides |
US3838598A (en) | 1969-03-28 | 1974-10-01 | Brunswick Corp | Capillary flow meter |
US3590634A (en) | 1969-05-05 | 1971-07-06 | Stanford Research Inst | Instrument for determining permeation rates through a membrane |
GB1363762A (en) | 1971-06-28 | 1974-08-14 | Atomic Energy Authority Uk | Fluid flow meters |
US3957653A (en) | 1975-04-03 | 1976-05-18 | Becton, Dickinson And Company | Apparatus for collection, separation and isolation of blood |
US4187952A (en) | 1976-03-04 | 1980-02-12 | Becton, Dickinson And Company | Cannula pierceable, self-sealing closure |
US4111326A (en) | 1976-03-04 | 1978-09-05 | Becton, Dickinson And Company | Closure for air evacuated container |
US4162528A (en) | 1976-05-18 | 1979-07-24 | Bell Telephone Laboratories, Incorporated | X-ray-fluorescence measurement of thin film thicknesses |
GB1513426A (en) | 1976-06-01 | 1978-06-07 | Aspro Nicholas Ltd | Packaging |
NO137663C (no) | 1976-09-30 | 1978-03-29 | Ken Heimreid | Fremgangsmaate ved undersoekelse av ukoagulert blod |
GB1566251A (en) | 1976-10-15 | 1980-04-30 | Gervase Instr Ltd | Flow meters |
JPS6010132B2 (ja) | 1976-11-18 | 1985-03-15 | 村田機械株式会社 | 捲覆糸 |
US4168330A (en) | 1977-10-13 | 1979-09-18 | Rca Corporation | Method of depositing a silicon oxide layer |
US4484479A (en) | 1978-04-05 | 1984-11-27 | Richard Eckhardt | Gas flow metering |
US4392218A (en) | 1979-01-02 | 1983-07-05 | Lanier Business Products, Inc. | Apparatus for identifying a dictate station by providing an automatically generated sequence of signals and a manually entered sequence of signals |
US4289726A (en) | 1979-07-02 | 1981-09-15 | Potoczky Joseph B | Apparatus and method for injection molding of elongated hollow plastic container walls |
JPS5627330A (en) | 1979-08-15 | 1981-03-17 | Yoshino Kogyosho Co Ltd | Heat treatment for internal wall surface of saturated polyester resin biaxially stretched bottle |
US4293078A (en) | 1979-11-01 | 1981-10-06 | Becton, Dickinson And Company | Vacuum indicator closure for a blood collection tube |
US4486378A (en) | 1980-05-07 | 1984-12-04 | Toyo Seikan Kaisha Ltd. | Plastic bottles and process for preparation thereof |
US4391128A (en) | 1981-04-20 | 1983-07-05 | Air Products And Chemicals, Inc. | Back-diffusion quality control method for barrier treated containers |
US4452679A (en) | 1981-10-07 | 1984-06-05 | Becton Dickinson And Company | Substrate with chemically modified surface and method of manufacture thereof |
US4422896A (en) | 1982-01-26 | 1983-12-27 | Materials Research Corporation | Magnetically enhanced plasma process and apparatus |
JPS58154602A (ja) | 1982-03-10 | 1983-09-14 | Nippon Kokan Kk <Nkk> | テイン・フリ−・スチ−ルの表面被膜厚測定方法及び装置 |
JPH0635323B2 (ja) | 1982-06-25 | 1994-05-11 | 株式会社日立製作所 | 表面処理方法 |
US4522510A (en) | 1982-07-26 | 1985-06-11 | Therma-Wave, Inc. | Thin film thickness measurement with thermal waves |
DE3239379A1 (de) | 1982-10-23 | 1984-04-26 | Helmut Fischer GmbH & Co Institut für Elektronik und Meßtechnik, 7032 Sindelfingen | Vorrichtung zum messen der dicke duenner schichten |
JPS5987307A (ja) | 1982-11-11 | 1984-05-19 | Nippon Kokan Kk <Nkk> | 表面被膜の膜厚測定装置 |
US4483737A (en) | 1983-01-31 | 1984-11-20 | University Of Cincinnati | Method and apparatus for plasma etching a substrate |
JPS59154029A (ja) | 1983-02-23 | 1984-09-03 | Nippon Telegr & Teleph Corp <Ntt> | 絶縁膜形成方法 |
JPS59168310A (ja) | 1983-03-02 | 1984-09-22 | エナ−ジ−・コンバ−シヨン・デバイセス・インコ−ポレ−テツド | 薄膜の厚みを測定する方法及び装置 |
US4478873A (en) | 1983-05-23 | 1984-10-23 | American Optical Corporation | Method imparting anti-static, anti-reflective properties to ophthalmic lenses |
JPS6010132A (ja) | 1983-06-29 | 1985-01-19 | Shimadzu Corp | 光学測定器 |
CA1199854A (fr) | 1983-08-31 | 1986-01-28 | Majesty (Her) The Queen In Right Of Canada As Represented By The Minister Of National Defence | Element a ecoulement laminaire |
US4524616A (en) | 1983-09-02 | 1985-06-25 | Tylan Corporation | Adjustable laminar flow bypass |
US4524089A (en) | 1983-11-22 | 1985-06-18 | Olin Corporation | Three-step plasma treatment of copper foils to enhance their laminate adhesion |
US4552791A (en) | 1983-12-09 | 1985-11-12 | Cosden Technology, Inc. | Plastic container with decreased gas permeability |
JPH0627323B2 (ja) | 1983-12-26 | 1994-04-13 | 株式会社日立製作所 | スパツタリング方法及びその装置 |
AT379069B (de) | 1984-01-11 | 1985-11-11 | Greiner & Soehne C A | Blutprobenroehrchen |
JPS60158316A (ja) | 1984-01-30 | 1985-08-19 | Osaka Gas Co Ltd | タ−ビン式流量計 |
GR850153B (fr) | 1984-02-06 | 1985-03-29 | Obrist Ag Crown | |
JPS6113626A (ja) | 1984-06-29 | 1986-01-21 | Hitachi Ltd | プラズマ処理装置 |
JPS6130036A (ja) | 1984-07-23 | 1986-02-12 | Fujitsu Ltd | マイクロ波プラズマ処理装置 |
EP0173164B1 (fr) | 1984-08-31 | 1988-11-09 | Hitachi, Ltd. | Vaporisation à l'aide de micro-ondes |
US4668365A (en) | 1984-10-25 | 1987-05-26 | Applied Materials, Inc. | Apparatus and method for magnetron-enhanced plasma-assisted chemical vapor deposition |
DE3444270A1 (de) | 1984-12-05 | 1986-06-05 | Helmut Fischer GmbH & Co Institut für Elektronik und Meßtechnik, 7032 Sindelfingen | Vorrichtung zum messen der dicke duenner schichten |
JPH0740468B2 (ja) | 1984-12-11 | 1995-05-01 | 株式会社日立製作所 | 高周波プラズマ発生装置 |
JPS61183462A (ja) | 1985-02-06 | 1986-08-16 | Yuugou Giken:Kk | 磁石やコイルの磁場を利用したパイプ等の内面イオンプレ−テイング装置及びその方法 |
CH667528A5 (de) | 1985-03-15 | 1988-10-14 | Alusuisse | Verfahren zum bestimmen der dicke von transparenten lackschichten und vorrichtung zu dessen ausfuehrung. |
US4767414A (en) | 1985-05-16 | 1988-08-30 | Becton, Dickinson And Company | Ionizing plasma lubricant method |
EP0221005A3 (fr) | 1985-09-07 | 1987-12-02 | Wagner, Wolfgang, Dr.med. | Dispositif d'injection avec capteur |
JPS6289401A (ja) | 1985-10-11 | 1987-04-23 | Mitsubishi Electric Corp | 列車における各種車載機器類の監視システム |
US4667620A (en) | 1985-10-29 | 1987-05-26 | Cosden Technology, Inc. | Method and apparatus for making plastic containers having decreased gas permeability |
JPS6289401U (fr) | 1985-11-25 | 1987-06-08 | ||
JPS62180069A (ja) | 1986-02-05 | 1987-08-07 | Kobe Steel Ltd | 管内面の被覆方法 |
US4824444A (en) | 1986-04-11 | 1989-04-25 | Applied Membrane Technology, Inc. | Gas permselective composite membrane prepared by plasma polymerization coating techniques |
JP2575653B2 (ja) | 1986-06-06 | 1997-01-29 | 日新電機株式会社 | 金属製筒形被コ−ティング材の筒内面への薄膜形成方法 |
US6248219B1 (en) | 1986-06-23 | 2001-06-19 | Unaxis Balzers Aktiengesellschaft | Process and apparatus for sputter etching or sputter coating |
JPS638524A (ja) | 1986-06-30 | 1988-01-14 | Yamatake Honeywell Co Ltd | 差圧発信器 |
ZA874580B (fr) | 1986-07-04 | 1988-01-04 | ||
US4778721A (en) | 1986-07-09 | 1988-10-18 | Battelle Memorial Institute | Method of forming abrasion-resistant plasma coatings and resulting articles |
US4697717A (en) | 1986-08-18 | 1987-10-06 | Becton, Dickinson And Company | Rubber/plastic stopper composite with mechanical adhesive joints |
DE3729347A1 (de) | 1986-09-05 | 1988-03-17 | Mitsubishi Electric Corp | Plasmaprozessor |
DE3632748A1 (de) | 1986-09-26 | 1988-04-07 | Ver Foerderung Inst Kunststoff | Verfahren zur beschichtung von hohlkoerpern |
US4756964A (en) | 1986-09-29 | 1988-07-12 | The Dow Chemical Company | Barrier films having an amorphous carbon coating and methods of making |
JP2587924B2 (ja) | 1986-10-11 | 1997-03-05 | 日本電信電話株式会社 | 薄膜形成装置 |
US4725481A (en) | 1986-10-31 | 1988-02-16 | E. I. Du Pont De Nemours And Company | Vapor-permeable, waterproof bicomponent structure |
JPS63124521A (ja) | 1986-11-14 | 1988-05-28 | Shin Etsu Chem Co Ltd | X線リソグラフイ−用マスク表面の処理方法 |
DE3774098D1 (de) | 1986-12-29 | 1991-11-28 | Sumitomo Metal Ind | Plasmageraet. |
US4741446A (en) | 1986-12-29 | 1988-05-03 | Becton, Dickinson And Company | Computer generated stopper |
US4853102A (en) | 1987-01-07 | 1989-08-01 | Hitachi, Ltd. | Sputtering process and an apparatus for carrying out the same |
SU1530913A1 (ru) | 1987-01-13 | 1989-12-23 | Казахский научно-исследовательский институт энергетики | Расходомер |
EP0275965B1 (fr) | 1987-01-19 | 1995-05-31 | Hitachi, Ltd. | Appareil opérant avec un plasma |
JPS63124521U (fr) | 1987-02-07 | 1988-08-15 | ||
EP0284867A2 (fr) | 1987-04-03 | 1988-10-05 | Tegal Corporation | Appareil de gravure sèche utilisant un confinement du plasma par champ magnétique de surface |
US5028566A (en) | 1987-04-10 | 1991-07-02 | Air Products And Chemicals, Inc. | Method of forming silicon dioxide glass films |
US4808453A (en) | 1987-04-13 | 1989-02-28 | Romberg Val G | Pharmaceutical elastomeric coating |
US5000994A (en) | 1987-04-13 | 1991-03-19 | The West Company, Incorporated | Pharmaceutical elastomeric coating |
US4973504A (en) | 1987-04-13 | 1990-11-27 | The West Company Incorporated | Pharmaceutical elastomeric coating |
US5203959A (en) | 1987-04-27 | 1993-04-20 | Semiconductor Energy Laboratory Co., Ltd. | Microwave plasma etching and deposition method employing first and second magnetic fields |
JPH0672306B2 (ja) | 1987-04-27 | 1994-09-14 | 株式会社半導体エネルギー研究所 | プラズマ処理装置およびプラズマ処理方法 |
DE3883985T2 (de) | 1987-06-19 | 1994-01-27 | Terumo Corp | Ärztliches instrument und dessen herstellung. |
ZA884511B (en) | 1987-07-15 | 1989-03-29 | Boc Group Inc | Method of plasma enhanced silicon oxide deposition |
JPS6423105A (en) | 1987-07-17 | 1989-01-25 | Japan Aviation Electron | Film thickness evaluating device |
KR920002864B1 (ko) | 1987-07-20 | 1992-04-06 | 가부시기가이샤 히다찌세이사꾸쇼 | 플라즈마 처리방법 및 그 장치 |
JPS6428509A (en) | 1987-07-23 | 1989-01-31 | Nippon Kokan Kk | Apparatus for measuring thickness of film |
US4842704A (en) | 1987-07-29 | 1989-06-27 | Collins George J | Magnetron deposition of ceramic oxide-superconductor thin films |
EP0327639B1 (fr) | 1987-08-24 | 1992-01-08 | General Electric Company | Articles en plastique resistants a l'abrasion et leur procede de fabrication |
US4809876A (en) | 1987-08-27 | 1989-03-07 | Aluminum Company Of America | Container body having improved gas barrier properties |
US4880120A (en) | 1987-09-02 | 1989-11-14 | The Coca-Cola Company | Plastic container inspection process |
GB2210826B (en) | 1987-10-19 | 1992-08-12 | Bowater Packaging Ltd | Barrier packaging materials |
DE3738993A1 (de) | 1987-11-17 | 1989-05-24 | Philips Patentverwaltung | Verfahren zur glimmentladungsaktivierten reaktiven abscheidung von metall aus einer gasphase |
US4886086A (en) | 1987-12-23 | 1989-12-12 | Graco, Inc. | Non-degrading pressure regulator |
JPH0668152B2 (ja) | 1988-01-27 | 1994-08-31 | 株式会社半導体エネルギー研究所 | 薄膜形成装置 |
US5798027A (en) | 1988-02-08 | 1998-08-25 | Optical Coating Laboratory, Inc. | Process for depositing optical thin films on both planar and non-planar substrates |
US4844986A (en) | 1988-02-16 | 1989-07-04 | Becton, Dickinson And Company | Method for preparing lubricated surfaces and product |
JPH01225775A (ja) | 1988-03-04 | 1989-09-08 | Toyo Sutoufuaa Chem:Kk | 管状材料内面に対するセラミック・コーティング膜の形成方法 |
US5041303A (en) | 1988-03-07 | 1991-08-20 | Polyplasma Incorporated | Process for modifying large polymeric surfaces |
US5275299A (en) | 1988-04-15 | 1994-01-04 | C. A. Greiner & Sohne Gesellschaft Mbh | Closure device for an in particular evacuable cylindrical housing |
US4880675A (en) | 1988-04-25 | 1989-11-14 | Air Products And Chemicals, Inc. | Hot-fillable plastic containers |
US5409782A (en) | 1988-05-02 | 1995-04-25 | Orient Watch Company | Composite film |
JP2599176B2 (ja) | 1988-05-02 | 1997-04-09 | オリエント時計 株式会社 | 金色装飾品 |
EP0343017A3 (fr) | 1988-05-20 | 1990-05-23 | Nec Corporation | Appareil de gravure ionique réactive |
US4883686A (en) | 1988-05-26 | 1989-11-28 | Energy Conversion Devices, Inc. | Method for the high rate plasma deposition of high quality material |
DE3820237C1 (fr) | 1988-06-14 | 1989-09-14 | Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften Ev, 3400 Goettingen, De | |
US4846101A (en) | 1988-07-01 | 1989-07-11 | Becton, Dickinson And Company | Apparatus for plasma treatment of small diameter tubes |
US4948628A (en) | 1988-07-01 | 1990-08-14 | Becton, Dickinson And Company | Method for plasma treatment of small diameter tubes |
JPH0224502A (ja) | 1988-07-12 | 1990-01-26 | Dainippon Screen Mfg Co Ltd | 膜厚測定方法 |
US4869203A (en) | 1988-07-18 | 1989-09-26 | Vapor Technologies Inc. | Apparatus for coating a metal gas-pressure bottle or tank |
DE3926023A1 (de) | 1988-09-06 | 1990-03-15 | Schott Glaswerke | Cvd-beschichtungsverfahren zur herstellung von schichten und vorrichtung zur durchfuehrung des verfahrens |
CA1335495C (fr) | 1988-12-22 | 1995-05-09 | Renate Foerch | Modification de surfaces polymeriques par des reactions a deux etapes |
GB8905075D0 (en) | 1989-03-06 | 1989-04-19 | Nordiko Ltd | Electrode assembly and apparatus |
US5472660A (en) | 1989-03-08 | 1995-12-05 | Fortex, Inc. | Method for the manufacture of shaped products of biaxially oriented polymeric material |
DE3908418C2 (de) | 1989-03-15 | 1999-06-02 | Buck Chem Tech Werke | Verfahren zum Innenbeschichten von Kunststoff-Behältern und Vorrichtung zum Beschichten |
US4999014A (en) | 1989-05-04 | 1991-03-12 | Therma-Wave, Inc. | Method and apparatus for measuring thickness of thin films |
US5042951A (en) | 1989-09-19 | 1991-08-27 | Therma-Wave, Inc. | High resolution ellipsometric apparatus |
EP0396919A3 (fr) | 1989-05-08 | 1991-07-10 | Applied Materials, Inc. | Réacteur à plasma et procédé de traitement de semi-conducteur |
US5225024A (en) | 1989-05-08 | 1993-07-06 | Applied Materials, Inc. | Magnetically enhanced plasma reactor system for semiconductor processing |
JPH02298024A (ja) | 1989-05-12 | 1990-12-10 | Tadahiro Omi | リアクティブイオンエッチング装置 |
US5429070A (en) | 1989-06-13 | 1995-07-04 | Plasma & Materials Technologies, Inc. | High density plasma deposition and etching apparatus |
US5297561A (en) | 1989-06-15 | 1994-03-29 | Hulon Walter C | Blood collection tube assembly |
US5032202A (en) | 1989-10-03 | 1991-07-16 | Martin Marietta Energy Systems, Inc. | Plasma generating apparatus for large area plasma processing |
US5044199A (en) | 1989-11-13 | 1991-09-03 | Dxl International, Inc. | Flowmeter |
JP2905828B2 (ja) | 1989-12-05 | 1999-06-14 | 株式会社吉野工業所 | シリンジ筒成形装置とシリンジ筒成形方法 |
US5067491A (en) | 1989-12-08 | 1991-11-26 | Becton, Dickinson And Company | Barrier coating on blood contacting devices |
JPH03183759A (ja) | 1989-12-12 | 1991-08-09 | Toyobo Co Ltd | 積層プラスチックフイルムおよびその製造方法 |
US5064083A (en) | 1990-03-08 | 1991-11-12 | The West Company, Incorporated | Closure device |
JP2706546B2 (ja) | 1990-03-08 | 1998-01-28 | 日東工器株式会社 | 内周面円筒状体のコーティング方法 |
AT401341B (de) | 1990-03-09 | 1996-08-26 | Greiner & Soehne C A | Verschlussvorrichtung für ein, insbesondere evakuierbares gehäuse |
DE4008405C1 (fr) | 1990-03-16 | 1991-07-11 | Schott Glaswerke, 6500 Mainz, De | |
JPH03271374A (ja) | 1990-03-22 | 1991-12-03 | Toshiba Corp | 薄膜形成装置 |
JPH04374A (ja) | 1990-04-16 | 1992-01-06 | Mitsubishi Heavy Ind Ltd | プラスチック基板表面の硬化保護膜製造方法 |
JPH04373A (ja) | 1990-04-16 | 1992-01-06 | Mitsubishi Heavy Ind Ltd | プラスチック基板表面の硬化保護膜製造方法 |
JPH04375A (ja) | 1990-04-16 | 1992-01-06 | Mitsubishi Heavy Ind Ltd | プラスチック基板表面の硬化保護膜製造方法 |
US5084356A (en) | 1990-04-20 | 1992-01-28 | E. I. Du Pont De Nemours And Company | Film coated with glass barrier layer with metal dopant |
US5085904A (en) | 1990-04-20 | 1992-02-04 | E. I. Du Pont De Nemours And Company | Barrier materials useful for packaging |
JPH0414440A (ja) | 1990-05-07 | 1992-01-20 | Toray Ind Inc | 積層フィルム |
US5443645A (en) | 1990-05-19 | 1995-08-22 | Canon Kabushiki Kaisha | Microwave plasma CVD apparatus comprising coaxially aligned multiple gas pipe gas feed structure |
DE4026367A1 (de) | 1990-06-25 | 1992-03-12 | Leybold Ag | Vorrichtung zum beschichten von substraten |
US5131752A (en) | 1990-06-28 | 1992-07-21 | Tamarack Scientific Co., Inc. | Method for film thickness endpoint control |
US6251792B1 (en) | 1990-07-31 | 2001-06-26 | Applied Materials, Inc. | Plasma etch processes |
US5079481A (en) | 1990-08-02 | 1992-01-07 | Texas Instruments Incorporated | Plasma-assisted processing magneton with magnetic field adjustment |
US5082542A (en) | 1990-08-02 | 1992-01-21 | Texas Instruments Incorporated | Distributed-array magnetron-plasma processing module and method |
EP0470777A3 (en) | 1990-08-07 | 1993-06-02 | The Boc Group, Inc. | Thin gas barrier films and rapid deposition method therefor |
US5192849A (en) | 1990-08-10 | 1993-03-09 | Texas Instruments Incorporated | Multipurpose low-thermal-mass chuck for semiconductor processing equipment |
JPH04110617A (ja) | 1990-08-31 | 1992-04-13 | Nippon Tairan Kk | マスフローコントローラーの分流構造 |
JP2916942B2 (ja) | 1990-09-14 | 1999-07-05 | 住友重機械工業株式会社 | 管内面のプラズマcvd処理方法及びその装置 |
CA2051219C (fr) | 1990-09-14 | 2001-06-19 | Yuji Komiya | Methode de preparation d'un materiau d'emballage lamine |
US5240774A (en) | 1990-10-25 | 1993-08-31 | Matsushita Electric Industrial Co., Ltd. | Fluorocarbon-based coating film and method of manufacturing the same |
DE69122212T2 (de) | 1990-10-25 | 1997-01-30 | Matsushita Electric Industrial Co., Ltd., Kadoma, Osaka | Durch chemische Adsorption laminierter monomolekularer Film und Verfahren zu seiner Herstellung |
US5779802A (en) | 1990-12-10 | 1998-07-14 | Imec V.Z.W. | Thin film deposition chamber with ECR-plasma source |
JP2965359B2 (ja) | 1991-01-07 | 1999-10-18 | 積水化学工業株式会社 | 血液検査用容器 |
JPH04236770A (ja) | 1991-01-17 | 1992-08-25 | Kobe Steel Ltd | 真空アーク蒸着のアークスポットの制御方法及び蒸発源 |
FR2671931A1 (fr) | 1991-01-22 | 1992-07-24 | Metal Process | Dispositif de repartition d'une energie micro-onde pour l'excitation d'un plasma. |
US5330578A (en) | 1991-03-12 | 1994-07-19 | Semiconductor Energy Laboratory Co., Ltd. | Plasma treatment apparatus |
DE4109619C1 (fr) | 1991-03-23 | 1992-08-06 | Leybold Ag, 6450 Hanau, De | |
JP2501490B2 (ja) | 1991-03-25 | 1996-05-29 | 日新製鋼株式会社 | タンデム圧延機の板厚制御装置 |
CA2067691C (fr) | 1991-05-13 | 1995-12-12 | James A. Burns | Bouchon etanche |
US5189446A (en) | 1991-05-17 | 1993-02-23 | International Business Machines Corporation | Plasma wafer processing tool having closed electron cyclotron resonance |
DE4119362A1 (de) | 1991-06-12 | 1992-12-17 | Leybold Ag | Teilchenquelle, insbesondere fuer reaktive ionenaetz- und plasmaunterstuetzte cvd-verfahren |
JPH056688A (ja) | 1991-06-20 | 1993-01-14 | Fujitsu Ltd | サンプル・アンド・ホールド回路 |
KR100255703B1 (ko) | 1991-06-27 | 2000-05-01 | 조셉 제이. 스위니 | 전자기 rf연결부를 사용하는 플라즈마 처리기 및 방법 |
US6518195B1 (en) | 1991-06-27 | 2003-02-11 | Applied Materials, Inc. | Plasma reactor using inductive RF coupling, and processes |
US5888414A (en) | 1991-06-27 | 1999-03-30 | Applied Materials, Inc. | Plasma reactor and processes using RF inductive coupling and scavenger temperature control |
US5633711A (en) | 1991-07-08 | 1997-05-27 | Massachusettes Institute Of Technology | Measurement of material properties with optically induced phonons |
DE4122802C1 (fr) | 1991-07-10 | 1992-12-17 | Schott Glaswerke, 6500 Mainz, De | |
US5198725A (en) | 1991-07-12 | 1993-03-30 | Lam Research Corporation | Method of producing flat ecr layer in microwave plasma device and apparatus therefor |
US5271274A (en) | 1991-08-14 | 1993-12-21 | The Board Of Trustees Of The Leland Stanford Junior University | Thin film process monitoring techniques using acoustic waves |
US5204141A (en) | 1991-09-18 | 1993-04-20 | Air Products And Chemicals, Inc. | Deposition of silicon dioxide films at temperatures as low as 100 degree c. by lpcvd using organodisilane sources |
JP3105962B2 (ja) | 1991-09-20 | 2000-11-06 | 株式会社豊田中央研究所 | 固体潤滑性を有する非晶質薄膜およびその製造方法 |
US5224441A (en) | 1991-09-27 | 1993-07-06 | The Boc Group, Inc. | Apparatus for rapid plasma treatments and method |
EP0535810B1 (fr) | 1991-10-03 | 1996-03-06 | Becton, Dickinson and Company | Tube pour le prélèvement du sang |
CA2268719C (fr) | 1991-10-03 | 2001-08-28 | Becton, Dickinson And Company | Dispositif de prelevement sanguin |
EP0537950B1 (fr) | 1991-10-17 | 1997-04-02 | Applied Materials, Inc. | Réacteur à plasma |
JP2647585B2 (ja) | 1991-11-28 | 1997-08-27 | 三菱電機株式会社 | 自動薄膜計測装置 |
US5333049A (en) | 1991-12-06 | 1994-07-26 | Hughes Aircraft Company | Apparatus and method for interferometrically measuring the thickness of thin films using full aperture irradiation |
US5372851A (en) | 1991-12-16 | 1994-12-13 | Matsushita Electric Industrial Co., Ltd. | Method of manufacturing a chemically adsorbed film |
US5397956A (en) | 1992-01-13 | 1995-03-14 | Tokyo Electron Limited | Electron beam excited plasma system |
DE4204082A1 (de) | 1992-02-12 | 1993-08-19 | Leybold Ag | Verfahren zur herstellung einer haftvermittelnden schicht auf werkstueckoberflaechen |
JPH05263223A (ja) | 1992-03-14 | 1993-10-12 | Nitto Kohki Co Ltd | 内側部を有する被コーティング体のコーティング方法及び装置 |
US5302266A (en) | 1992-03-20 | 1994-04-12 | International Business Machines Corporation | Method and apparatus for filing high aspect patterns with metal |
DE4209384C1 (fr) | 1992-03-23 | 1993-04-22 | Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung Ev, 8000 Muenchen, De | |
US5444207A (en) | 1992-03-26 | 1995-08-22 | Kabushiki Kaisha Toshiba | Plasma generating device and surface processing device and method for processing wafers in a uniform magnetic field |
DE69324849T2 (de) | 1992-04-16 | 1999-09-23 | Mitsubishi Heavy Ind Ltd | Verfahren und Vorrichtung zur Plasma-unterstützten chemischen Dampfphasen-Abscheidung |
DE4214401C1 (en) | 1992-04-30 | 1993-03-11 | Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften Ev, 3400 Goettingen, De | Plasma-aided CVD of coating inside hollow body - by introducing atmos. contg. cpd. vapour into cavity at below atmos. pressure and passing microwaves into cavity |
CA2095674A1 (fr) | 1992-05-13 | 1993-11-14 | Nicholas A. Grippi | Tube de prelevement du sang |
EP0571896B1 (fr) | 1992-05-27 | 1996-08-28 | Matsushita Electric Industrial Co., Ltd. | Procédé de fabrication d'un film absorbé chimiquement |
MX9303141A (es) | 1992-05-28 | 1994-04-29 | Polar Materials Inc | Metodos y aparatos para depositar recubrimientos de barrera. |
US5486701A (en) | 1992-06-16 | 1996-01-23 | Prometrix Corporation | Method and apparatus for measuring reflectance in two wavelength bands to enable determination of thin film thickness |
US5286297A (en) | 1992-06-24 | 1994-02-15 | Texas Instruments Incorporated | Multi-electrode plasma processing apparatus |
US5252178A (en) | 1992-06-24 | 1993-10-12 | Texas Instruments Incorporated | Multi-zone plasma processing method and apparatus |
US5308649A (en) | 1992-06-26 | 1994-05-03 | Polar Materials, Inc. | Methods for externally treating a container with application of internal bias gas |
JPH0610132A (ja) | 1992-06-29 | 1994-01-18 | Nagasaki Pref Gov | 有機シリコン化合物薄膜の製造方法 |
US5812261A (en) | 1992-07-08 | 1998-09-22 | Active Impulse Systems, Inc. | Method and device for measuring the thickness of opaque and transparent films |
CA2100275A1 (fr) | 1992-07-22 | 1994-01-23 | Mitchell K. Antoon, Jr. | Dispositif de prelevement sanguin |
US5272735A (en) | 1992-08-03 | 1993-12-21 | Combustion Engineering, Inc. | Sputtering process burnable poison coating |
US5531683A (en) | 1992-08-13 | 1996-07-02 | Science Incorporated | Mixing and delivery syringe assembly |
US5292370A (en) | 1992-08-14 | 1994-03-08 | Martin Marietta Energy Systems, Inc. | Coupled microwave ECR and radio-frequency plasma source for plasma processing |
US5260095A (en) | 1992-08-21 | 1993-11-09 | Battelle Memorial Institute | Vacuum deposition and curing of liquid monomers |
GB9219450D0 (en) | 1992-09-15 | 1992-10-28 | Glaverbel | Thin film thickness monitoring and control |
TW267975B (fr) | 1992-10-20 | 1996-01-11 | Toppan Printing Co Ltd | |
US5433345A (en) | 1992-10-28 | 1995-07-18 | Dai Nippon Printing Co., Ltd. | Bag-in-carton and pouring spout thereof |
JP2501490Y2 (ja) | 1992-11-24 | 1996-06-19 | 正雄 筑波 | 額縁類取付具 |
CA2085805A1 (fr) | 1992-12-18 | 1994-06-19 | Jaromir Friedrich | Dispositif pour mesurer le debit d'un fluide |
AU669754B2 (en) | 1992-12-18 | 1996-06-20 | Becton Dickinson & Company | Barrier coating |
CA2110761A1 (fr) | 1992-12-18 | 1994-06-19 | Yelena G. Tropsha | Etiquette a couche de barrage |
US5298587A (en) | 1992-12-21 | 1994-03-29 | The Dow Chemical Company | Protective film for articles and method |
TW249313B (fr) | 1993-03-06 | 1995-06-11 | Tokyo Electron Co | |
JP3274217B2 (ja) | 1993-04-05 | 2002-04-15 | 株式会社リコー | 液晶表示装置の製造方法 |
AU5914994A (en) | 1993-04-21 | 1994-10-27 | Bend Research, Inc. | Plasma polymerization and surface modification inside hollow micro-substrates |
US5494170A (en) | 1993-05-06 | 1996-02-27 | Becton Dickinson And Company | Combination stopper-shield closure |
US5632396A (en) | 1993-05-06 | 1997-05-27 | Becton, Dickinson And Company | Combination stopper-shield closure |
PE9895A1 (es) | 1993-05-13 | 1995-05-15 | Coca Cola Co | Metodo para obtener un envase para bebidas teniendo una superficie interna con una permeabilidad/absorcion relativamente baja |
IL109589A0 (en) | 1993-05-14 | 1994-08-26 | Hughes Aircraft Co | Apparatus and method for performing high spatial resolution thin film layer thickness metrology |
DE4316349C2 (de) | 1993-05-15 | 1996-09-05 | Ver Foerderung Inst Kunststoff | Verfahren zur Innenbeschichtung von Hohlkörpern mit organischen Deckschichten durch Plasmapolymerisation, sowie Vorrichtung zur Durchführung des Verfahrens |
ES2117789T3 (es) | 1993-06-01 | 1998-08-16 | Kautex Textron Gmbh & Co Kg | Procedimiento para producir un recubrimiento polimero en cuerpos huecos de materia plastica. |
CH685755A5 (de) | 1993-06-03 | 1995-09-29 | Tetra Pak Suisse Sa | Verfahren zur Herstellung eines Schichtstoffes. |
JP2803017B2 (ja) | 1993-06-07 | 1998-09-24 | 工業技術院長 | 抗血栓性医用材料及び医療用具並びにこれらの製造方法、製造装置及びプラズマ処理装置 |
US5361921A (en) | 1993-06-29 | 1994-11-08 | Becton Dickinson And Company | Combination stopper-shield closure |
JP3369261B2 (ja) | 1993-08-02 | 2003-01-20 | 東洋紡績株式会社 | ガスバリア性容器 |
US5356029A (en) | 1993-08-25 | 1994-10-18 | Kaneka Texas Corporation | Bin-type bulk fluid container |
JP3183759B2 (ja) | 1993-08-26 | 2001-07-09 | 株式会社三協精機製作所 | 負荷測定装置 |
US5433786A (en) | 1993-08-27 | 1995-07-18 | The Dow Chemical Company | Apparatus for plasma enhanced chemical vapor deposition comprising shower head electrode with magnet disposed therein |
JPH0768614A (ja) | 1993-09-03 | 1995-03-14 | Olympus Optical Co Ltd | 光学素子の射出成形金型および射出成形方法 |
US5512399A (en) | 1993-09-21 | 1996-04-30 | Fuji Electric Co., Ltd. | Organic photo sensitive member for electrophotography |
US5364666A (en) | 1993-09-23 | 1994-11-15 | Becton, Dickinson And Company | Process for barrier coating of plastic objects |
CA2130388A1 (fr) | 1993-09-23 | 1995-03-24 | Joel L. Williams | Procede de revetement d'isolement pour objets en plastique |
US5381228A (en) | 1993-09-30 | 1995-01-10 | Hoover Universal, Inc. | Rapid estimation of the oxygen permeation rate of a thin film on a plastic container |
US5440446A (en) | 1993-10-04 | 1995-08-08 | Catalina Coatings, Inc. | Acrylate coating material |
EP0722787B1 (fr) | 1993-10-04 | 2002-06-05 | 3M Innovative Properties Company | Procédé pour fabriquer un revêtement en acrylate |
KR100276736B1 (ko) | 1993-10-20 | 2001-03-02 | 히가시 데쓰로 | 플라즈마 처리장치 |
US5449432A (en) | 1993-10-25 | 1995-09-12 | Applied Materials, Inc. | Method of treating a workpiece with a plasma and processing reactor having plasma igniter and inductive coupler for semiconductor fabrication |
FR2711647B1 (fr) | 1993-10-27 | 1996-01-19 | Europ Propulsion | Procédé d'infiltration chimique en phase vapeur d'un matériau au sein d'un substrat poreux à température de surface contrôlée. |
US5679412A (en) | 1993-10-28 | 1997-10-21 | Manfred R. Kuehnle | Method and apparatus for producing gas impermeable, chemically inert container structures for food and volatile substances |
JPH07126419A (ja) | 1993-11-04 | 1995-05-16 | Toppan Printing Co Ltd | ガスバリア性積層体 |
US5413813A (en) | 1993-11-23 | 1995-05-09 | Enichem S.P.A. | CVD of silicon-based ceramic materials on internal surface of a reactor |
US5354286A (en) | 1993-12-07 | 1994-10-11 | Survival Technology, Inc. | Injection device having polyparaxylylene coated container |
AT400802B (de) | 1993-12-16 | 1996-03-25 | Greiner & Soehne C A | Haltevorrichtung für ein blutprobenentnahmeröhrchen einer blutabnahmevorrichtung |
US5871700A (en) | 1993-12-21 | 1999-02-16 | C.A. Greiner & Sohne Gesellschaft M.B.H. | Holding device with a cylindrical container and blood sampling tube with such a holding device |
US5439736A (en) | 1994-01-21 | 1995-08-08 | Neomecs Incorporated | Gas plasma polymerized permselective membrane |
EP0665304B1 (fr) | 1994-01-31 | 1997-08-13 | Nissin Electric Company, Limited | Procédé pour la fabrication d'un tube ayant un film à sa surface intérieure périphérique et appareillage pour la fabrication de ce tube |
CH687601A5 (de) | 1994-02-04 | 1997-01-15 | Tetra Pak Suisse Sa | Verfahren zur Herstellung von im Innern sterilen Verpackungen mit hervorragenden Sperreigenschaften. |
US5565248A (en) | 1994-02-09 | 1996-10-15 | The Coca-Cola Company | Method and apparatus for coating hollow containers through plasma-assisted deposition of an inorganic substance |
ATE179914T1 (de) | 1994-02-16 | 1999-05-15 | Coca Cola Co | Hohler behälter mit inerter oder undurchlässiger innerer oberfläche durch plasmaunterstütze oberflächereaktion oder in situ polymerisation |
US6149982A (en) | 1994-02-16 | 2000-11-21 | The Coca-Cola Company | Method of forming a coating on an inner surface |
US5618619A (en) | 1994-03-03 | 1997-04-08 | Monsanto Company | Highly abrasion-resistant, flexible coatings for soft substrates |
US5569810A (en) | 1994-03-18 | 1996-10-29 | Samco International, Inc. | Method of and system for processing halogenated hydrocarbons |
US5620523A (en) | 1994-04-11 | 1997-04-15 | Canon Sales Co., Inc. | Apparatus for forming film |
US5593550A (en) | 1994-05-06 | 1997-01-14 | Medtronic, Inc. | Plasma process for reducing friction within the lumen of polymeric tubing |
JPH07304127A (ja) | 1994-05-13 | 1995-11-21 | Toppan Printing Co Ltd | ガスバリヤー性包装材料およびその製造方法 |
US5670415A (en) | 1994-05-24 | 1997-09-23 | Depositech, Inc. | Method and apparatus for vacuum deposition of highly ionized media in an electromagnetic controlled environment |
US5514246A (en) | 1994-06-02 | 1996-05-07 | Micron Technology, Inc. | Plasma reactors and method of cleaning a plasma reactor |
GB9411626D0 (en) | 1994-06-10 | 1994-08-03 | Smithkline Beecham Plc | Package |
EP0955951B1 (fr) | 1994-07-01 | 2005-08-24 | Edwards Lifesciences Corporation | Appareil de prelevement de tissus adipeux contenant des cellules endotheliales microvasculaires autologues |
US5452082A (en) | 1994-07-05 | 1995-09-19 | Uop | Flow cell with leakage detection |
US5536253A (en) | 1994-07-15 | 1996-07-16 | Habley Medical Technology Corporation | Pre-filled safety syringe having a retractable needle |
JPH0825244A (ja) | 1994-07-21 | 1996-01-30 | Besutoma Kk | ボルト継手における締結力の管理装置 |
US5578103A (en) | 1994-08-17 | 1996-11-26 | Corning Incorporated | Alkali metal ion migration control |
US5521351A (en) | 1994-08-30 | 1996-05-28 | Wisconsin Alumni Research Foundation | Method and apparatus for plasma surface treatment of the interior of hollow forms |
US5510155A (en) | 1994-09-06 | 1996-04-23 | Becton, Dickinson And Company | Method to reduce gas transmission |
JPH0884773A (ja) | 1994-09-14 | 1996-04-02 | Taisei Kako Kk | 非晶性樹脂製の抜き勾配を有しない注射筒及びその射出成形方法 |
US5545375A (en) | 1994-10-03 | 1996-08-13 | Becton, Dickinson And Company | Blood collection tube assembly |
DE4437050A1 (de) | 1994-10-17 | 1996-04-18 | Leybold Ag | Vorrichtung zum Behandeln von Oberflächen von Hohlkörpern, insbesondere von Innenflächen von Kraftstofftanks |
DE4438359C2 (de) | 1994-10-27 | 2001-10-04 | Schott Glas | Behälter aus Kunststoff mit einer Sperrbeschichtung |
DE4438360C2 (de) | 1994-10-27 | 1999-05-20 | Schott Glas | Vorfüllbare partikelarme, sterile Einmalspritze für die Injektion von Präparaten und Verfahren zu ihrer Herstellung |
US6083628A (en) | 1994-11-04 | 2000-07-04 | Sigma Laboratories Of Arizona, Inc. | Hybrid polymer film |
DE4445427C2 (de) | 1994-12-20 | 1997-04-30 | Schott Glaswerke | Plasma-CVD-Verfahren zur Herstellung einer Gradientenschicht |
DE4445969C1 (de) | 1994-12-22 | 1996-03-14 | Schott Glaswerke | Spritzenzylinder für eine Zweikammer-Fertigspritze, Zweikammer-Fertigspritze und Verfahren zum Herstellen und Füllen derselben |
JP3022229B2 (ja) | 1994-12-26 | 2000-03-15 | 東洋製罐株式会社 | プラスチックス材料からなる立体形状の容器に均一の膜厚の珪素酸化物被膜を形成する方法 |
MX9705922A (es) | 1995-02-01 | 1997-10-31 | Schneider Usa Inc | Procedimientos para hidrofilizar polimeros hidrofobos. |
JPH08288096A (ja) | 1995-02-13 | 1996-11-01 | Mitsubishi Electric Corp | プラズマ処理装置 |
EP0728676A1 (fr) | 1995-02-25 | 1996-08-28 | TNT Limited | Echantillonneur pour un conteneur flexible |
US5877895A (en) | 1995-03-20 | 1999-03-02 | Catalina Coatings, Inc. | Multicolor interference coating |
JP2920187B2 (ja) | 1995-04-28 | 1999-07-19 | 日新電機株式会社 | 管体内周面に膜形成する方法及び装置 |
US5674321A (en) | 1995-04-28 | 1997-10-07 | Applied Materials, Inc. | Method and apparatus for producing plasma uniformity in a magnetic field-enhanced plasma reactor |
US5485091A (en) | 1995-05-12 | 1996-01-16 | International Business Machines Corporation | Contactless electrical thin oxide measurements |
US5513515A (en) | 1995-05-15 | 1996-05-07 | Modern Controls, Inc. | Method for measuring permeability of a material |
US5555471A (en) | 1995-05-24 | 1996-09-10 | Wyko Corporation | Method for measuring thin-film thickness and step height on the surface of thin-film/substrate test samples by phase-shifting interferometry |
JPH095038A (ja) | 1995-06-15 | 1997-01-10 | Nkk Corp | クロメート処理鋼板のクロメート被膜厚測定方法及び装置 |
JP4245661B2 (ja) | 1995-06-26 | 2009-03-25 | ゼネラル・エレクトリック・カンパニイ | 多重被膜で保護した遮熱コーティング複合物 |
US5840167A (en) | 1995-08-14 | 1998-11-24 | Lg Semicon Co., Ltd | Sputtering deposition apparatus and method utilizing charged particles |
WO1997011482A2 (fr) | 1995-09-05 | 1997-03-27 | Lsi Logic Corporation | Elimination d'halogenes et de vernis photosensible de tranches |
US5837903A (en) | 1995-09-22 | 1998-11-17 | The Scott Fetzer Company Inc. | Device for measuring exhaust flowrate using laminar flow element |
US5779716A (en) | 1995-10-06 | 1998-07-14 | Metamorphic Surgical Devices, Inc. | Device for removing solid objects from body canals, cavities and organs |
US5591898A (en) | 1995-10-12 | 1997-01-07 | Modern Controls, Inc. | Method for measuring material permeability characteristics |
CN1074006C (zh) | 1995-10-13 | 2001-10-31 | 陶氏化学公司 | 涂覆的塑料基材 |
DK0819617T3 (da) | 1995-10-18 | 2001-03-05 | Daikyo Seiko Ltd | Plasthætte og fremgangsmåde til fremstilling af denne |
US6210791B1 (en) | 1995-11-30 | 2001-04-03 | General Electric Company | Article with a diffuse reflective barrier coating and a low-emissity coating thereon, and its preparation |
US5985103A (en) | 1995-12-19 | 1999-11-16 | Micron Technology, Inc. | Method for improved bottom and side wall coverage of high aspect ratio features |
US5658438A (en) | 1995-12-19 | 1997-08-19 | Micron Technology, Inc. | Sputter deposition method for improved bottom and side wall coverage of high aspect ratio features |
US6471822B1 (en) | 1996-01-24 | 2002-10-29 | Applied Materials, Inc. | Magnetically enhanced inductively coupled plasma reactor with magnetically confined plasma |
TW303480B (en) | 1996-01-24 | 1997-04-21 | Applied Materials Inc | Magnetically confined plasma reactor for processing a semiconductor wafer |
US5763033A (en) | 1996-01-30 | 1998-06-09 | Becton, Dickinson And Company | Blood collection tube assembly |
US5686157A (en) | 1996-01-30 | 1997-11-11 | Becton, Dickinson And Company | Blood collection tube assembly |
US5702770A (en) | 1996-01-30 | 1997-12-30 | Becton, Dickinson And Company | Method for plasma processing |
US5683771A (en) | 1996-01-30 | 1997-11-04 | Becton, Dickinson And Company | Blood collection tube assembly |
US5955161A (en) | 1996-01-30 | 1999-09-21 | Becton Dickinson And Company | Blood collection tube assembly |
US5716683A (en) | 1996-01-30 | 1998-02-10 | Becton, Dickinson And Company | Blood collection tube assembly |
US5738920A (en) | 1996-01-30 | 1998-04-14 | Becton, Dickinson And Company | Blood collection tube assembly |
TW434301B (en) | 1996-01-30 | 2001-05-16 | Becton Dickinson Co | Non-ideal barrier coating composition comprising organic and inorganic materials |
CA2277679C (fr) | 1996-01-30 | 2003-06-10 | Becton, Dickinson And Company | Dispositif de prelevement sanguin |
US5737179A (en) | 1996-02-07 | 1998-04-07 | Catalina Coatings, Inc. | Metallized film capacitor |
US5667840A (en) | 1996-02-27 | 1997-09-16 | Becton Dickinson And Company | Lubricant soluble fluorescent agent and method for its use in a system for detection of lubricant coatings |
US6160350A (en) | 1996-03-25 | 2000-12-12 | Sumitomo Heavy Industries, Ltd. | Ion plating apparatus |
US6106678A (en) | 1996-03-29 | 2000-08-22 | Lam Research Corporation | Method of high density plasma CVD gap-filling |
WO1997040207A1 (fr) | 1996-04-22 | 1997-10-30 | N.V. Bekaert S.A. | Compositions nanocomposites de type diamant |
US5888591A (en) | 1996-05-06 | 1999-03-30 | Massachusetts Institute Of Technology | Chemical vapor deposition of fluorocarbon polymer thin films |
US6020196A (en) | 1996-05-09 | 2000-02-01 | Baxter International Inc. | Devices for harvesting and homogenizing adipose tissue containing autologous endothelial cells |
JP3256459B2 (ja) | 1996-05-20 | 2002-02-12 | 株式会社大協精工 | 衛生品用容器及びその製造方法 |
EP0814114A1 (fr) | 1996-06-18 | 1997-12-29 | Becton, Dickinson and Company | Couche barrière |
JPH108254A (ja) | 1996-06-21 | 1998-01-13 | Toyota Motor Corp | 二酸化ケイ素層の形成方法 |
US6190992B1 (en) | 1996-07-15 | 2001-02-20 | Micron Technology, Inc. | Method to achieve rough silicon surface on both sides of container for enhanced capacitance/area electrodes |
US6145688A (en) | 1996-07-17 | 2000-11-14 | Smith; James C. | Closure device for containers |
US6161712A (en) | 1996-07-22 | 2000-12-19 | Becton Dickinson And Company | Ball and socket closure |
DE19629877C1 (de) | 1996-07-24 | 1997-03-27 | Schott Glaswerke | CVD-Verfahren und Vorrichtung zur Innenbeschichtung von Hohlkörpern |
US5900284A (en) | 1996-07-30 | 1999-05-04 | The Dow Chemical Company | Plasma generating device and method |
AT404317B (de) | 1996-08-02 | 1998-10-27 | Greiner & Soehne C A | Verschlussvorrichtung, trennvorrichtung sowie aufnahmebehälter für eine aufnahmeeinrichtung |
JP3198065B2 (ja) | 1996-08-19 | 2001-08-13 | 株式会社大協精工 | 衛生品用容器 |
JP3945664B2 (ja) | 1996-09-06 | 2007-07-18 | 治 高井 | 撥水性酸化シリコン皮膜の製造方法 |
US5750892A (en) | 1996-09-27 | 1998-05-12 | Teledyne Industries, Inc. | Laminar flow element with inboard sensor taps and coaxial laminar flow guides |
US5792940A (en) | 1996-09-30 | 1998-08-11 | Becton, Dickinson And Company | Rapid evaluation of thin-film barrier coatings on thick substrates via transient response measurements |
US5766362A (en) | 1996-09-30 | 1998-06-16 | Becton Dickinson And Company | Apparatus for depositing barrier film on three-dimensional articles |
US5691007A (en) | 1996-09-30 | 1997-11-25 | Becton Dickinson And Company | Process for depositing barrier film on three-dimensional articles |
US5807343A (en) | 1996-09-30 | 1998-09-15 | Becton Dickinson And Company | Protective sealing barrier for a syringe |
US6112695A (en) | 1996-10-08 | 2000-09-05 | Nano Scale Surface Systems, Inc. | Apparatus for plasma deposition of a thin film onto the interior surface of a container |
US6027619A (en) | 1996-12-19 | 2000-02-22 | Micron Technology, Inc. | Fabrication of field emission array with filtered vacuum cathodic arc deposition |
US5913140A (en) | 1996-12-23 | 1999-06-15 | Lam Research Corporation | Method for reduction of plasma charging damage during chemical vapor deposition |
HUP0000081A3 (en) | 1996-12-23 | 2000-07-28 | Novo Nordisk As | A medicament container of polymer of cyclic hydrocarbon for storing a liquid medicament |
AR009439A1 (es) | 1996-12-23 | 2000-04-12 | Novartis Ag | Un articulo que comprende un sustrato con un recubrimiento polimerico primario que porta grupos reactivos predominantemente en su superficie, unmetodo para preparar dicho articulo, un articulo que posee un recubrimiento de tipo hibrido y una lente de contacto |
US7268179B2 (en) | 1997-02-03 | 2007-09-11 | Cytonix Corporation | Hydrophobic coating compositions, articles coated with said compositions, and processes for manufacturing same |
US5824607A (en) | 1997-02-06 | 1998-10-20 | Applied Materials, Inc. | Plasma confinement for an inductively coupled plasma reactor |
DE19706255C2 (de) | 1997-02-18 | 2000-11-30 | Schott Glas | Sterilisierbarer Glasbehälter für medizinische Zwecke, insbesondere zur Aufbewahrung pharmazeutischer oder diagnostischer Produkte |
DE19707645A1 (de) | 1997-02-26 | 1998-08-27 | Leybold Ag | Verfahren zur Schichtdickenanalyse und stofflichen Konzentrationsbestimmung dünner Schichten |
US6223683B1 (en) | 1997-03-14 | 2001-05-01 | The Coca-Cola Company | Hollow plastic containers with an external very thin coating of low permeability to gases and vapors through plasma-assisted deposition of inorganic substances and method and system for making the coating |
US20020155299A1 (en) | 1997-03-14 | 2002-10-24 | Harris Caroline S. | Photo-induced hydrophilic article and method of making same |
JP3582287B2 (ja) | 1997-03-26 | 2004-10-27 | 株式会社日立製作所 | エッチング装置 |
US6017317A (en) | 1997-03-26 | 2000-01-25 | Becton Dickinson And Company | Assembly for collecting blood or other body fluids |
US5800880A (en) | 1997-03-26 | 1998-09-01 | Tetra Laval Holdings & Finance, S.A. | Process for coating the interior wall of a container with a SiOx barrier layer |
WO1998045871A1 (fr) | 1997-04-04 | 1998-10-15 | Alexander Igorevich Dodonov | Production d'un plasma par arc electrique dans un guide a plasma curviligne et revetement de substrat |
US6261643B1 (en) | 1997-04-08 | 2001-07-17 | General Electric Company | Protected thermal barrier coating composite with multiple coatings |
US5880034A (en) | 1997-04-29 | 1999-03-09 | Princeton University | Reduction of semiconductor structure damage during reactive ion etching |
US5814738A (en) | 1997-05-01 | 1998-09-29 | Mccrometer, Inc. | Fluid flow meter and mixer having removable and replaceable displacement member |
US5837888A (en) | 1997-05-14 | 1998-11-17 | Modern Controls, Inc. | Process for measuring vapor transmission through materials |
JP3387775B2 (ja) | 1997-05-22 | 2003-03-17 | 株式会社大協精工 | 注射器用密封栓及びプレフィルド注射器 |
JPH10335314A (ja) | 1997-06-05 | 1998-12-18 | Mitsubishi Electric Corp | プラズマ処理装置及び基板処理方法 |
JPH111770A (ja) | 1997-06-06 | 1999-01-06 | Anelva Corp | スパッタリング装置及びスパッタリング方法 |
US6110544A (en) | 1997-06-26 | 2000-08-29 | General Electric Company | Protective coating by high rate arc plasma deposition |
CA2241678C (fr) | 1997-06-26 | 2007-08-28 | General Electric Company | Depot de dioxyde de silicium par un procede d'evaporation active par un plasma |
US6135053A (en) | 1997-07-16 | 2000-10-24 | Canon Kabushiki Kaisha | Apparatus for forming a deposited film by plasma chemical vapor deposition |
US6001429A (en) | 1997-08-07 | 1999-12-14 | Becton Dickinson And Company | Apparatus and method for plasma processing |
US5861546A (en) | 1997-08-20 | 1999-01-19 | Sagi; Nehemiah Hemi | Intelligent gas flow measurement and leak detection apparatus |
US6110395A (en) | 1997-08-26 | 2000-08-29 | Trikon Technologies, Inc. | Method and structure for controlling plasma uniformity |
US5902461A (en) | 1997-09-03 | 1999-05-11 | Applied Materials, Inc. | Apparatus and method for enhancing uniformity of a metal film formed on a substrate with the aid of an inductively coupled plasma |
DE19739321C2 (de) | 1997-09-09 | 2001-09-27 | Helmut Fischer Gmbh & Co | Verfahren und Einrichtung zum Bestimmen der Meßunsicherheit bei Röntgenfluoreszenz-Schichtdickenmessungen |
US5972297A (en) | 1997-09-12 | 1999-10-26 | Becton, Dickinson & Company | Ball and socket closure for specimen collection container incorporating a septum |
US6350415B1 (en) | 1997-09-12 | 2002-02-26 | Becton, Dickinson And Company | Ball and socket closure for specimen collection container incorporating a dimple locking mechanism |
US6032813A (en) | 1997-09-12 | 2000-03-07 | Becton, Dickinson And Company | Ball and socket closure for specimen collection container incorporating an integral flexible seal |
US5948364A (en) | 1997-09-12 | 1999-09-07 | Becton Dickinson & Company | Ball and socket closure for specimen collection container |
US5919420A (en) | 1997-09-12 | 1999-07-06 | Becton Dickinson And Company | Ball and socket closure for specimen collection container incorporating a resilient elastomeric seal |
US6757056B1 (en) | 2001-03-26 | 2004-06-29 | Candela Instruments | Combined high speed optical profilometer and ellipsometer |
JPH11102799A (ja) | 1997-09-26 | 1999-04-13 | Mitsubishi Electric Corp | プラズマ発生装置 |
EP1019943A1 (fr) | 1997-09-30 | 2000-07-19 | Tetra Laval Holdings & Finance S.A. | Dispositif et procede pour le traitement, dans un procede active par plasma, de la surface interieure d'un recipient en plastique presentant une ouverture etroite |
CA2304613A1 (fr) | 1997-09-30 | 1999-04-08 | Jacques Laurent | Procede et appareil pour le traitement de la surface interieure de bouteilles en plastique, dans un procede active par plasma |
JPH11108833A (ja) | 1997-10-06 | 1999-04-23 | Mitsubishi Chemical Corp | 物質の分光分析法 |
US6124212A (en) | 1997-10-08 | 2000-09-26 | Taiwan Semiconductor Manufacturing Co. | High density plasma (HDP) etch method for suppressing micro-loading effects when etching polysilicon layers |
JPH11106920A (ja) | 1997-10-08 | 1999-04-20 | Nissin Electric Co Ltd | 容器及びその製造方法 |
US6365013B1 (en) | 1997-11-03 | 2002-04-02 | Siemens Aktiengesellschaft | Coating method and device |
GB9723222D0 (en) | 1997-11-04 | 1998-01-07 | Pilkington Plc | Coating glass |
US6051151A (en) | 1997-11-12 | 2000-04-18 | International Business Machines Corporation | Apparatus and method of producing a negative ion plasma |
SE511139C2 (sv) | 1997-11-20 | 1999-08-09 | Hana Barankova | Plasmabearbetningsapparat med vridbara magneter |
US6136165A (en) | 1997-11-26 | 2000-10-24 | Cvc Products, Inc. | Apparatus for inductively-coupled-plasma-enhanced ionized physical-vapor deposition |
US5961911A (en) | 1997-12-05 | 1999-10-05 | Becton Dickinson And Company | Process for manufacture of closure assembly |
KR100256173B1 (ko) | 1997-12-22 | 2000-05-15 | 윤종용 | 반도체장치 제조용 플라즈마 식각 챔버 |
JPH11193470A (ja) | 1997-12-26 | 1999-07-21 | Canon Inc | 堆積膜形成装置及び堆積膜形成方法 |
US6162443A (en) | 1998-01-09 | 2000-12-19 | Abbott Laboratories | Container for an inhalation anesthetic |
DE19801861C2 (de) | 1998-01-20 | 2001-10-18 | Schott Glas | Verfahren zum Herstellen eines hohlen, innenbeschichteten Glasformkörpers |
JPH11218418A (ja) | 1998-02-03 | 1999-08-10 | Seiko Instruments Inc | インライン蛍光x線膜厚モニタ |
US6163006A (en) | 1998-02-06 | 2000-12-19 | Astex-Plasmaquest, Inc. | Permanent magnet ECR plasma source with magnetic field optimization |
US6103074A (en) | 1998-02-14 | 2000-08-15 | Phygen, Inc. | Cathode arc vapor deposition method and apparatus |
US5993745A (en) | 1998-03-04 | 1999-11-30 | Roche Diagnostics Corporation | Archival storage tray for multiple test tubes |
JP3669138B2 (ja) | 1998-03-05 | 2005-07-06 | 日新電機株式会社 | プラズマcvd法、プラズマcvd装置及び電極 |
US6482509B2 (en) | 1998-03-06 | 2002-11-19 | Novo Nordisk A/S | Coating system providing low friction |
US6189484B1 (en) | 1999-03-05 | 2001-02-20 | Applied Materials Inc. | Plasma reactor having a helicon wave high density plasma source |
EP1061974A1 (fr) | 1998-03-13 | 2000-12-27 | Becton, Dickinson and Company | Procede de fabrication, de remplissage et de conditionnement de contenants medicaux |
JP3698887B2 (ja) | 1998-03-16 | 2005-09-21 | 株式会社アルバック | ダイヤモンド状炭素膜の製造装置 |
DE19983045T1 (de) | 1998-03-17 | 2001-03-22 | Becton Dickinson Co | Vorfüllbare Spritze mit einem Polymersilikon-Schmiermittel |
US6243938B1 (en) | 1998-03-17 | 2001-06-12 | Becton, Dickinson And Company | Low silicone plastic prefillable syringe |
DE19912737A1 (de) | 1998-03-19 | 2000-06-21 | Henning Nagel | Verfahren zur Herstellung von porösen SiO¶x¶-Schichten und poröse SiO¶x¶-Schichten |
FR2776540B1 (fr) | 1998-03-27 | 2000-06-02 | Sidel Sa | Recipient en matiere a effet barriere et procede et appareil pour sa fabrication |
KR20010042128A (ko) | 1998-03-31 | 2001-05-25 | 드로그.와이.윌렘스,렉토 | 2축으로 텍스처된 코팅의 침착 방법 및 장치 |
JPH11297673A (ja) | 1998-04-15 | 1999-10-29 | Hitachi Ltd | プラズマ処理装置及びクリーニング方法 |
WO1999054924A1 (fr) | 1998-04-21 | 1999-10-28 | Hitachi, Ltd. | Dispositif et procede permettant de mesurer l'epaisseur d'un film mince, et procede et dispositif de production d'un film mince utilisant les premiers |
US6068884A (en) | 1998-04-28 | 2000-05-30 | Silcon Valley Group Thermal Systems, Llc | Method of making low κ dielectric inorganic/organic hybrid films |
US5951527A (en) | 1998-05-05 | 1999-09-14 | Daikyo Seiko, Ltd | Sliding piston for syringe |
US6217716B1 (en) | 1998-05-06 | 2001-04-17 | Novellus Systems, Inc. | Apparatus and method for improving target erosion in hollow cathode magnetron sputter source |
US6035717A (en) | 1998-05-12 | 2000-03-14 | Krautkramer Branson, Inc. | Method and apparatus for measuring the thickness of a coated material |
US6271047B1 (en) | 1998-05-21 | 2001-08-07 | Nikon Corporation | Layer-thickness detection methods and apparatus for wafers and the like, and polishing apparatus comprising same |
US6015595A (en) | 1998-05-28 | 2000-01-18 | Felts; John T. | Multiple source deposition plasma apparatus |
JPH11344316A (ja) | 1998-05-29 | 1999-12-14 | Futec Inc | 膜厚測定方法 |
US6093175A (en) | 1998-06-05 | 2000-07-25 | Becton Dickinson And Company | Localized lubrication of syringe barrels and stoppers |
JP4254058B2 (ja) | 1998-06-30 | 2009-04-15 | 日本ゼオン株式会社 | 容器およびブロー成形体 |
US20010042510A1 (en) | 1998-07-08 | 2001-11-22 | The Coca-Cola Company | Hollow containers with inert or impermeable inner surface through plasma-assisted surface reaction or on-surface polymerization |
DE19830794B4 (de) | 1998-07-09 | 2005-10-27 | Singulus Technologies Ag | Schichtdickenmeßsystem und -verfahren |
US7798993B2 (en) | 1998-07-29 | 2010-09-21 | Becton, Dickinson And Company | Single use syringe |
US6018987A (en) | 1998-08-03 | 2000-02-01 | Mocon, Inc. | Apparatus for measuring gas transmission through container closures |
JP3437772B2 (ja) | 1998-08-17 | 2003-08-18 | 長崎県 | 管内面の表面処理方法及び装置 |
US6125687A (en) | 1998-08-20 | 2000-10-03 | International Business Machines Corporation | Apparatus for measuring outgassing of volatile materials from an object |
US6009743A (en) | 1998-08-24 | 2000-01-04 | Mocon, Inc. | Apparatus and method for online or offline measurement of vapor transmission through sheet materials |
WO2000019507A1 (fr) | 1998-09-28 | 2000-04-06 | Tokyo Electron Limited | Depot de film assiste par plasma |
US6165138A (en) | 1998-09-30 | 2000-12-26 | Becton Dickinson And Company | Self-sealing closure for a medical speciman collection container |
JP2000127290A (ja) | 1998-09-30 | 2000-05-09 | Becton Dickinson & Co | バリア被覆および高出力プラズマ化学気相成長法によってプラスチック物体上にバリア被覆を堆積する方法 |
JP2000109076A (ja) | 1998-10-01 | 2000-04-18 | Toppan Printing Co Ltd | 内面コートボトルおよびその製造方法 |
US6236459B1 (en) | 1998-11-05 | 2001-05-22 | University Of Miami | Thin film measuring device and method |
US6596401B1 (en) | 1998-11-10 | 2003-07-22 | C. R. Bard Inc. | Silane copolymer compositions containing active agents |
KR100341565B1 (ko) | 1998-11-11 | 2002-06-22 | 김윤 | 젖음성이 우수한 표면을 갖는 불소계 수지 |
US6486081B1 (en) | 1998-11-13 | 2002-11-26 | Applied Materials, Inc. | Gas distribution system for a CVD processing chamber |
US6263249B1 (en) | 1999-02-26 | 2001-07-17 | Medtronic, Inc. | Medical electrical lead having controlled texture surface and method of making same |
US6204922B1 (en) | 1998-12-11 | 2001-03-20 | Filmetrics, Inc. | Rapid and accurate thin film measurement of individual layers in a multi-layered or patterned sample |
IT1310330B1 (it) | 1999-02-05 | 2002-02-13 | Tre Esse Progettazione Biomedi | Sistema a catetere per eseguire un trattamento terapeuticointramiocardico. |
IT1304783B1 (it) | 1998-12-14 | 2001-03-29 | Tre Esse Progettazione Biomedi | Metodo ed apparato per eseguire un trattamento terapeuticointramiocardico. |
EP1140278B1 (fr) | 1998-12-14 | 2004-05-19 | Tre Esse Progettazione Biomedica S.r.l | Systeme de catheter pour traitement therapeutique intramyocardique |
US6207238B1 (en) | 1998-12-16 | 2001-03-27 | Battelle Memorial Institute | Plasma enhanced chemical deposition for high and/or low index of refraction polymers |
AT407007B (de) | 1998-12-23 | 2000-11-27 | Greiner Labortechnik Gmbh | Aufnahmeeinrichtung für ein einsatzelement |
US6165542A (en) | 1998-12-23 | 2000-12-26 | United Technologies Corporation | Method for fabricating and inspecting coatings |
WO2000037206A2 (fr) | 1998-12-23 | 2000-06-29 | Applied Science And Technology, Inc. | Source de plasma ecr a aimants permanents assurant le confinement magnetique multipolaire integre |
US6188079B1 (en) | 1999-01-12 | 2001-02-13 | Owens-Brockway Glass Container Inc. | Measurement of hot container wall thickness |
US6774018B2 (en) | 1999-02-01 | 2004-08-10 | Sigma Laboratories Of Arizona, Inc. | Barrier coatings produced by atmospheric glow discharge |
US6193853B1 (en) | 1999-02-25 | 2001-02-27 | Cametoid Limited | Magnetron sputtering method and apparatus |
US6284986B1 (en) | 1999-03-15 | 2001-09-04 | Seh America, Inc. | Method of determining the thickness of a layer on a silicon substrate |
SE520491C2 (sv) | 1999-04-07 | 2003-07-15 | Tetra Laval Holdings & Finance | Förpackningslaminat med barriäregenskaper mot gas och aromämnen |
US6645354B1 (en) | 2000-04-07 | 2003-11-11 | Vladimir I. Gorokhovsky | Rectangular cathodic arc source and method of steering an arc spot |
US6929727B2 (en) | 1999-04-12 | 2005-08-16 | G & H Technologies, Llc | Rectangular cathodic arc source and method of steering an arc spot |
DE59912579D1 (de) | 1999-04-28 | 2006-02-02 | Alcan Tech & Man Ag | Verfahren und Vorrichtung zur Herstellung von Packungen |
US6582823B1 (en) | 1999-04-30 | 2003-06-24 | North Carolina State University | Wear-resistant polymeric articles and methods of making the same |
DE19921303C1 (de) | 1999-05-07 | 2000-10-12 | Schott Glas | Glasbehälter für medizinische Zwecke |
ATE315527T1 (de) | 1999-05-28 | 2006-02-15 | Novo Nordisk As | Spritzgegossener stopfen für arzneimittelbehälter |
US6306132B1 (en) | 1999-06-17 | 2001-10-23 | Vivant Medical | Modular biopsy and microwave ablation needle delivery apparatus adapted to in situ assembly and method of use |
US6399944B1 (en) | 1999-07-09 | 2002-06-04 | Fei Company | Measurement of film thickness by inelastic electron scattering |
US6085927A (en) | 1999-07-12 | 2000-07-11 | Owens-Illinois Closure Inc. | Container with insert to reduce effective volume and package incorporating same |
DE19932082A1 (de) | 1999-07-12 | 2001-01-18 | Schott Glas | Interferenzoptisches Schmalbandfilter |
US6185992B1 (en) | 1999-07-15 | 2001-02-13 | Veeco Instruments Inc. | Method and system for increasing the accuracy of a probe-based instrument measuring a heated sample |
JP3226512B2 (ja) | 1999-07-19 | 2001-11-05 | 東洋ガラス株式会社 | ガラス容器のコーティング検査方法及び装置 |
US6083313A (en) | 1999-07-27 | 2000-07-04 | Advanced Refractory Technologies, Inc. | Hardcoats for flat panel display substrates |
US6054188A (en) | 1999-08-02 | 2000-04-25 | Becton Dickinson And Company | Non-ideal barrier coating architecture and process for applying the same to plastic substrates |
DE19938724A1 (de) | 1999-08-16 | 2001-02-22 | Tetra Laval Holdings & Finance | Vorrichtung zur Herstellung von Kunststoffbehältern mittels Streckblasformen |
US6143140A (en) | 1999-08-16 | 2000-11-07 | Applied Materials, Inc. | Method and apparatus to improve the side wall and bottom coverage in IMP process by using magnetic field |
EP1077086B1 (fr) | 1999-08-18 | 2004-10-27 | Becton Dickinson and Company | Dispositif de fermeture comportant un bouchon et un capuchon protecteur |
US6410926B1 (en) | 1999-10-01 | 2002-06-25 | Ppg Industries Ohio, Inc. | Coating with optical taggent |
CA2286414A1 (fr) | 1999-10-04 | 2001-04-04 | Zhibo Gan | Dosage heterogene et sans separation de substances biologiques |
US6959284B1 (en) | 1999-10-06 | 2005-10-25 | John L. Howes | Containerized liquid coating product supply business method |
US6413645B1 (en) | 2000-04-20 | 2002-07-02 | Battelle Memorial Institute | Ultrabarrier substrates |
US6623861B2 (en) | 2001-04-16 | 2003-09-23 | Battelle Memorial Institute | Multilayer plastic substrates |
US6322661B1 (en) | 1999-11-15 | 2001-11-27 | Lam Research Corporation | Method and apparatus for controlling the volume of a plasma |
SE521904C2 (sv) | 1999-11-26 | 2003-12-16 | Ladislav Bardos | Anordning för hybridplasmabehandling |
SE0004353L (sv) | 1999-12-06 | 2001-06-07 | Greiner Bio One Gmbh | Anordning i form av ett kärl och/eller förslutning |
US6308556B1 (en) | 1999-12-17 | 2001-10-30 | Atc, Inc. | Method and apparatus of nondestructive testing a sealed product for leaks |
US6584828B2 (en) | 1999-12-17 | 2003-07-01 | Atc, Inc. | Method and apparatus of nondestructive testing a sealed product for leaks |
DE19961574A1 (de) | 1999-12-21 | 2001-07-19 | Koenig & Bauer Ag | Zylinder einer Rollenrotationsdruckmaschine |
DE19963122A1 (de) | 1999-12-24 | 2001-06-28 | Tetra Laval Holdings & Finance | Anordnung zum Einkoppeln von Mikrowellenenergie in eine Behandlungskammer |
WO2001054816A1 (fr) | 2000-01-27 | 2001-08-02 | Greiner Bio-One Gmbh | Recipient pour contenir des liquides |
DE10004274A1 (de) | 2000-02-01 | 2001-08-02 | Tetra Laval Holdings & Finance | Vorrichtung zum Beschichten der inneren Oberfläche eines Hohlkörpers |
JP3697250B2 (ja) | 2000-02-24 | 2005-09-21 | 三菱重工業株式会社 | プラズマ処理装置及び炭素被覆形成プラスチック容器の製造方法 |
JP4492985B2 (ja) | 2000-02-24 | 2010-06-30 | 三菱商事プラスチック株式会社 | 液体医薬品用プラスチック容器及び液体医薬品の保存回収方法 |
DE60116284T2 (de) | 2000-03-01 | 2006-08-10 | Plastic Technologies, Inc., Holland | Messung der mittleren wandstärke eines kunststoffbehälters |
DE10010831A1 (de) | 2000-03-10 | 2001-09-13 | Pierre Flecher | Niederdruck-Mikrowellenplasmabehandlung von Kunststoffflaschen |
US20010038894A1 (en) | 2000-03-14 | 2001-11-08 | Minoru Komada | Gas barrier film |
DE10012446B4 (de) | 2000-03-15 | 2007-06-14 | Tetra Laval Holdings & Finance S.A. | Verfahren zum Messen der Gasdurchlässigkeit einer Beschichtung auf einer Kunststoffwandung und Vorrichtung zur Durchführung des Verfahrens |
US6853141B2 (en) | 2002-05-22 | 2005-02-08 | Daniel J. Hoffman | Capacitively coupled plasma reactor with magnetic plasma control |
AT414209B (de) | 2000-03-17 | 2006-10-15 | Greiner Bio One Gmbh | Sammelgefäss für flüssigkeiten |
US6382441B1 (en) | 2000-03-22 | 2002-05-07 | Becton, Dickinson And Company | Plastic tube and resealable closure having protective collar |
US7067034B2 (en) | 2000-03-27 | 2006-06-27 | Lam Research Corporation | Method and apparatus for plasma forming inner magnetic bucket to control a volume of a plasma |
WO2001073159A1 (fr) | 2000-03-27 | 2001-10-04 | Mitsubishi Heavy Industries, Ltd. | Procede et appareil permettant de former un film metallique |
US20030010454A1 (en) | 2000-03-27 | 2003-01-16 | Bailey Andrew D. | Method and apparatus for varying a magnetic field to control a volume of a plasma |
US20040039401A1 (en) | 2000-03-31 | 2004-02-26 | Chow Alan Y. | Implant instrument |
CA2305938C (fr) | 2000-04-10 | 2007-07-03 | Vladimir I. Gorokhovsky | Methode et appareillage de depot d'arc cathodique filtre |
DE10018015A1 (de) | 2000-04-11 | 2001-10-25 | Infineon Technologies Ag | Anordnung zur Durchführung eines plasmabasierten Verfahrens |
DE10019355A1 (de) | 2000-04-18 | 2001-10-31 | Schott Glas | Glaskörper mit erhöhter Festigkeit |
US6562189B1 (en) | 2000-05-19 | 2003-05-13 | Applied Materials Inc. | Plasma reactor with a tri-magnet plasma confinement apparatus |
GB0012170D0 (en) | 2000-05-20 | 2000-07-12 | Harcostar Drums Limited | Treatment of plastics containers |
JP2001338912A (ja) | 2000-05-29 | 2001-12-07 | Tokyo Electron Ltd | プラズマ処理装置および処理方法 |
US6213985B1 (en) | 2000-06-06 | 2001-04-10 | Bracco Diagnostics, Inc. | Tapered syringe barrel with tapered plunger |
EP1299461A2 (fr) | 2000-06-06 | 2003-04-09 | The Dow Chemical Company | Couche de protection de transmission pour polymeres et conteneurs |
US6394979B1 (en) | 2000-06-09 | 2002-05-28 | Inviro Medical Devices Ltd. | Cannula for use with a medical syringe |
AU2001268404A1 (en) | 2000-06-14 | 2001-12-24 | The Procter And Gamble Company | Long lasting coatings for modifying hard surfaces and processes for applying the same |
CN1240761C (zh) | 2000-06-20 | 2006-02-08 | 三井化学株式会社 | 可交联的橡胶组合物及其应用 |
US6375022B1 (en) | 2000-06-30 | 2002-04-23 | Becton, Dickinson And Company | Resealable closure for containers |
JP3860954B2 (ja) | 2000-07-07 | 2006-12-20 | 株式会社日立グローバルストレージテクノロジーズ | リアルタイムパーティクルフィルタを具備したプラズマ処理装置 |
US6352629B1 (en) | 2000-07-10 | 2002-03-05 | Applied Materials, Inc. | Coaxial electromagnet in a magnetron sputtering reactor |
US6346596B1 (en) | 2000-07-14 | 2002-02-12 | Valspar Corporation | Gas barrier polymer composition |
US6354452B1 (en) | 2000-07-25 | 2002-03-12 | Becton, Dickinson And Company | Collection container assembly |
US6749078B2 (en) | 2000-07-25 | 2004-06-15 | Becton, Dickinson And Company | Collection assembly |
JP2002107134A (ja) | 2000-07-27 | 2002-04-10 | Seiko Instruments Inc | 蛍光x線膜厚計 |
EP1178134A1 (fr) | 2000-08-04 | 2002-02-06 | Cold Plasma Applications C.P.A. | Procédé et dispositif pour traiter des substrats métalliques au défilé par plasma |
GB0100958D0 (en) | 2001-01-13 | 2001-02-28 | Surface Technology Systems Ltd | Plasma processing apparatus |
US20020185226A1 (en) | 2000-08-10 | 2002-12-12 | Lea Leslie Michael | Plasma processing apparatus |
US6720052B1 (en) | 2000-08-24 | 2004-04-13 | The Coca-Cola Company | Multilayer polymeric/inorganic oxide structure with top coat for enhanced gas or vapor barrier and method for making same |
JP2002086481A (ja) | 2000-09-14 | 2002-03-26 | Terumo Corp | ガスケットの製造方法 |
ATE489726T1 (de) | 2000-09-19 | 2010-12-15 | Mattson Tech Inc | Verfahren zur ausbildung dielektrischer filme |
US6806951B2 (en) | 2000-09-20 | 2004-10-19 | Kla-Tencor Technologies Corp. | Methods and systems for determining at least one characteristic of defects on at least two sides of a specimen |
CH694949A5 (de) | 2000-09-22 | 2005-09-30 | Tetra Laval Holdings & Finance | Verfahren und Vorrichtung zur Behandlung von Oberflaechen mit Hilfe eines Glimmentladungs-Plasmas. |
TR200400076T4 (tr) | 2000-10-04 | 2004-02-23 | Dow Corning Ireland Limited | Bir kılıf oluşturmaya yarayan metot ve aparat |
US6551267B1 (en) | 2000-10-18 | 2003-04-22 | Becton, Dickinson And Company | Medical article having blood-contacting surface |
FR2815954B1 (fr) | 2000-10-27 | 2003-02-21 | Commissariat Energie Atomique | Procede et dispositif de depot par plasma a la resonance cyclotron electronique de nanotubes de carbone monoparois et nanotubes ainsi obtenus |
KR20030051765A (ko) | 2000-11-01 | 2003-06-25 | 어플라이드 머티어리얼즈 인코포레이티드 | 기판내의 고 애스펙트 비 형성체의 에칭 |
US20070258894A1 (en) | 2000-11-08 | 2007-11-08 | Melker Richard J | System and Method for Real-Time Diagnosis, Treatment, and Therapeutic Drug Monitoring |
US20050054942A1 (en) | 2002-01-22 | 2005-03-10 | Melker Richard J. | System and method for therapeutic drug monitoring |
FR2816926B1 (fr) | 2000-11-20 | 2003-02-14 | Becton Dickinson France | Emballage multifonctionnels, et plus particulierement emballages destines a transporter des produits sterilises ou destines a etre sterilises |
US20020070647A1 (en) | 2000-12-11 | 2002-06-13 | Andrey Ginovker | Nanostructure plasma source |
JP4698020B2 (ja) | 2000-12-19 | 2011-06-08 | テルモ株式会社 | 薬剤収納容器 |
AU2001222223A1 (en) | 2000-12-21 | 2002-07-01 | Mitsubishi Shoji Plastics Corporation | Apparatus for manufacturing dlc-film-coated plastic container, method of manufacturing the same, and method for cleaning inner electrode |
JP2002206167A (ja) | 2000-12-28 | 2002-07-26 | Toshiba Corp | プラズマコーティング装置及びプラズマコーティング方法 |
BRPI0206669B8 (pt) | 2001-01-24 | 2021-06-22 | Becton Dickinson Co | dispositivo médico compreendendo revestimento lubrificante |
US6680621B2 (en) | 2001-01-26 | 2004-01-20 | Semiconductor Diagnostics, Inc. | Steady state method for measuring the thickness and the capacitance of ultra thin dielectric in the presence of substantial leakage current |
US6597193B2 (en) | 2001-01-26 | 2003-07-22 | Semiconductor Diagnostics, Inc. | Steady state method for measuring the thickness and the capacitance of ultra thin dielectric in the presence of substantial leakage current |
US6640615B1 (en) | 2001-01-26 | 2003-11-04 | Darrell R. Morrow | System for determining the integrity of a package or packaging material based on its transmission of a test gas |
EP1229068B1 (fr) | 2001-02-06 | 2005-09-14 | Shibuya Kogyo Co., Ltd. | Méthode et dispositif pour modifier la surface intérieure de récipients en plastique |
US6673199B1 (en) | 2001-03-07 | 2004-01-06 | Applied Materials, Inc. | Shaping a plasma with a magnetic field to control etch rate uniformity |
DE10112731A1 (de) | 2001-03-14 | 2002-10-02 | Schott Glas | Beschichtung von Substraten |
DE10114401B4 (de) | 2001-03-23 | 2005-03-17 | Tetra Laval Holdings & Finance S.A. | Verfahren zum Blasformen eines Behälters aus Kunststoff und zum Beschichten des Behälterinneren |
US20020182101A1 (en) | 2001-03-27 | 2002-12-05 | Pavel Koulik | Process and device for plasma surface treatment |
US7288293B2 (en) | 2001-03-27 | 2007-10-30 | Apit Corp. S.A. | Process for plasma surface treatment and device for realizing the process |
JP3954319B2 (ja) | 2001-03-28 | 2007-08-08 | 株式会社東芝 | 薄膜の膜厚モニタリング方法及び基板温度測定方法 |
JP3833900B2 (ja) | 2001-03-28 | 2006-10-18 | 株式会社東芝 | エッチング装置およびエッチング方法 |
JP4085593B2 (ja) | 2001-03-29 | 2008-05-14 | 日新電機株式会社 | 真空アーク蒸着装置 |
US20040161623A1 (en) | 2001-03-29 | 2004-08-19 | Domine Joseph D | Ionomer laminates and articles formed from ionomer laminates |
AT500247B1 (de) | 2001-03-30 | 2007-06-15 | Greiner Bio One Gmbh | Aufnahmeeinrichtung, insbesondere für körperflüssigkeiten, mit einer trennvorrichtung sowie trennvorrichtung hierzu |
US6595961B2 (en) | 2001-04-16 | 2003-07-22 | Becton, Dickinson And Company | Sterilizable transfer or storage device for medicaments, drugs and vaccines |
US20020150709A1 (en) | 2001-04-16 | 2002-10-17 | Hetzler Kevin George | Method of fusing a component to a medical storage or transfer device and container assembly |
US20020153103A1 (en) | 2001-04-20 | 2002-10-24 | Applied Process Technologies, Inc. | Plasma treatment apparatus |
WO2002086185A1 (fr) | 2001-04-20 | 2002-10-31 | Applied Process Technologies | Source de plasma de decharge de penning |
DE10119571C1 (de) | 2001-04-21 | 2002-11-28 | Schott Glas | Verfahren zum gleichmäßigen Beschichten von Hohlkörpern und deren Verwendung |
US20030119193A1 (en) | 2001-04-25 | 2003-06-26 | Robert Hess | System and method for high throughput screening of droplets |
ATE254192T1 (de) | 2001-04-27 | 2003-11-15 | Europ Economic Community | Verfahren und vorrichtung zur sequentiellen plasmabehandlung |
TW570876B (en) | 2001-05-11 | 2004-01-11 | Toyo Seikan Kaisha Ltd | Silicon oxide film |
JP4014440B2 (ja) | 2001-05-11 | 2007-11-28 | 松下電器産業株式会社 | 情報記録装置、情報記録方法及び情報記録システム |
US20020170495A1 (en) | 2001-05-17 | 2002-11-21 | Ngk Insulators, Ltd. | Method for fabricating a thin film and apparatus for fabricating a thin film |
US7362425B2 (en) | 2001-05-18 | 2008-04-22 | Meeks Steven W | Wide spatial frequency topography and roughness measurement |
US7180849B2 (en) | 2001-05-18 | 2007-02-20 | Sharp Kabushiki Kaisha | Optical storage medium enabling uniform light transmittance, optical read/write apparatus for same, and optical read/write method for same |
DE10124225B4 (de) | 2001-05-18 | 2006-03-02 | Tetra Laval Holdings & Finance S.A. | Verfahren und Vorrichtung zum Bestimmen der Permeation einer Barriereschicht |
US20030215652A1 (en) | 2001-06-04 | 2003-11-20 | O'connor Paul J. | Transmission barrier layer for polymers and containers |
US20030123302A1 (en) | 2001-06-05 | 2003-07-03 | Thompson Robert F. | Limited play optical devices with interstitial reactive layer and methods of making same |
JP3678361B2 (ja) | 2001-06-08 | 2005-08-03 | 大日本印刷株式会社 | ガスバリアフィルム |
US6397776B1 (en) | 2001-06-11 | 2002-06-04 | General Electric Company | Apparatus for large area chemical vapor deposition using multiple expanding thermal plasma generators |
WO2002100928A1 (fr) | 2001-06-12 | 2002-12-19 | North Carolina State University | Revetements d'arret pour materiaux elastomeres |
JP4774635B2 (ja) | 2001-06-15 | 2011-09-14 | 凸版印刷株式会社 | 3次元中空容器への薄膜成膜装置及びそれを用いた薄膜成膜方法 |
JP2004532756A (ja) | 2001-06-18 | 2004-10-28 | ベクトン・ディキンソン・アンド・カンパニー | 多層容器および多層容器の形成方法 |
WO2003006181A1 (fr) | 2001-07-10 | 2003-01-23 | 3M Innovative Properties Company | Dispositifs d'inhalation de medicaments et composants a revetement forme par depot chimique en phase vapeur thermique |
JP3932836B2 (ja) | 2001-07-27 | 2007-06-20 | 株式会社日立製作所 | 薄膜の膜厚計測方法及びその装置並びにそれを用いたデバイスの製造方法 |
DE10139305A1 (de) | 2001-08-07 | 2003-03-06 | Schott Glas | Verbundmaterial aus einem Substratmaterial und einem Barriereschichtmaterial |
DE10138696A1 (de) | 2001-08-07 | 2003-03-06 | Schott Glas | Verfahren und Vorrichtung zum gleichzeitigen Beschichten und Formen eines dreidimensionalen Körpers |
JP2003050115A (ja) | 2001-08-07 | 2003-02-21 | Seiko Instruments Inc | X線膜厚計 |
US20030029837A1 (en) | 2001-08-10 | 2003-02-13 | Applied Materials, Inc. | Dielectric etch plasma chamber utilizing a magnetic filter to optimize plasma characteristics |
JP2004537448A (ja) | 2001-08-20 | 2004-12-16 | ノバ−プラズマ インコーポレイテッド | 気体および蒸気に対する浸透度の低いコーティング |
JP4812991B2 (ja) | 2001-09-20 | 2011-11-09 | 東京エレクトロン株式会社 | プラズマ処理装置 |
WO2003025497A1 (fr) | 2001-09-21 | 2003-03-27 | Kmac | Procede et dispositif de mesure du profil d'epaisseur et de la repartition des indices de refraction de couches multiples de films minces par reflectometrie bidimensionnelle |
US20030058413A1 (en) | 2001-09-26 | 2003-03-27 | Barnhurst Jeffrey E. | Visible light modifier and method |
DE10150738C1 (de) | 2001-10-13 | 2003-05-22 | Schott Glas | Verfahren zur Herstellung eines Glasrohres mit strahlungsabsorbierender alterungsbeständiger Beschichtung sowie desssen Verwendung |
US6766682B2 (en) | 2001-10-19 | 2004-07-27 | Desert Cryogenics Llc | Precise measurement system for barrier materials |
EP1448807A4 (fr) | 2001-10-30 | 2005-07-13 | Massachusetts Inst Technology | Copolymeres de fluorocarbone-organosilicium et revetements prepares par depot chimique en phase vapeur par filament chaud |
US7569035B1 (en) | 2001-11-02 | 2009-08-04 | Meridian Medical Technologies, Inc. | Automatic injector with anti-coring needle |
DE10154404C1 (de) | 2001-11-06 | 2003-06-18 | Ovd Kinegram Ag Zug | Verfahren und Vorrichtung zur Messung physikalischer Kenngrößen von dünnen, optisch transparenten Schichten und Vorrichtung zur Durchführung des Verfahrens |
WO2003044240A1 (fr) | 2001-11-15 | 2003-05-30 | Ionic Fusion Corporation | Appareil de depot par plasma ionique |
US6948448B2 (en) | 2001-11-27 | 2005-09-27 | General Electric Company | Apparatus and method for depositing large area coatings on planar surfaces |
JP2003234331A (ja) | 2001-12-05 | 2003-08-22 | Tokyo Electron Ltd | プラズマエッチング方法およびプラズマエッチング装置 |
JP4067817B2 (ja) | 2001-12-07 | 2008-03-26 | 日精エー・エス・ビー機械株式会社 | 容器のコーティング装置 |
KR100782651B1 (ko) | 2001-12-13 | 2007-12-07 | 미츠비시 쥬고교 가부시키가이샤 | 플라스틱 용기 내면에의 탄소막 형성 장치 및 내면 탄소막 피복 플라스틱 용기의 제조 방법 |
US7348055B2 (en) | 2001-12-21 | 2008-03-25 | Surmodics, Inc. | Reagent and method for providing coatings on surfaces |
DE10201110B4 (de) | 2002-01-15 | 2006-09-28 | Schott Ag | Behälter für Parenteralia/Injectabila |
US6752899B1 (en) | 2002-01-16 | 2004-06-22 | Advanced Micro Devices, Inc. | Acoustic microbalance for in-situ deposition process monitoring and control |
JP3953821B2 (ja) | 2002-01-17 | 2007-08-08 | ファブソリューション株式会社 | 膜厚測定方法および膜厚測定装置 |
JP2003305121A (ja) | 2002-04-16 | 2003-10-28 | Jfe Steel Kk | 医療用セラミック被覆針の製造方法 |
WO2003061490A1 (fr) | 2002-01-22 | 2003-07-31 | Kawasaki Steel Corporation | Instruments a usage medical revetus de ceramique, instruments revetus de ceramique pour l'etude d'organismes vivants et procede de production |
DE10202311B4 (de) | 2002-01-23 | 2007-01-04 | Schott Ag | Vorrichtung und Verfahren zur Plasmabehandlung von dielektrischen Körpern |
AU2003207794A1 (en) | 2002-02-05 | 2003-09-02 | Dow Global Technologies Inc. | Corona-generated chemical vapor deposition on a substrate |
JP3863029B2 (ja) | 2002-02-07 | 2006-12-27 | 大成化工株式会社 | 肩部を有する容器内面への粉体塗装装置並びに粉体塗装方法 |
US6684683B2 (en) | 2002-02-27 | 2004-02-03 | General Electric Company | Method and apparatus for characterizing the barrier properties of members of combinatorial libraries |
US6816570B2 (en) | 2002-03-07 | 2004-11-09 | Kla-Tencor Corporation | Multi-technique thin film analysis tool |
JP4031654B2 (ja) | 2002-03-12 | 2008-01-09 | 三菱商事プラスチック株式会社 | Cvd成膜装置及びcvd成膜装置用内部電極の清掃方法 |
JP4124609B2 (ja) | 2002-04-03 | 2008-07-23 | エスアイアイ・ナノテクノロジー株式会社 | 半導体製造工程におけるパターン部膜厚の測定方法と測定装置 |
AU2003236307A1 (en) | 2002-04-08 | 2003-10-20 | Kabushiki Kaisha Toshiba | Plasma etching method and plasma etching device |
WO2003085717A1 (fr) | 2002-04-08 | 2003-10-16 | Tokyo Electron Limited | Procede de gravure au plasma |
US6876154B2 (en) | 2002-04-24 | 2005-04-05 | Trikon Holdings Limited | Plasma processing apparatus |
GB0209291D0 (en) | 2002-04-24 | 2002-06-05 | Trikon Technologies Ltd | Plasma processing apparatus |
US20050233091A1 (en) | 2002-05-08 | 2005-10-20 | Devendra Kumar | Plasma-assisted coating |
US20060228497A1 (en) | 2002-05-08 | 2006-10-12 | Satyendra Kumar | Plasma-assisted coating |
US20050223988A1 (en) | 2002-05-24 | 2005-10-13 | Stephen Behle | Coating device comprising a conveying device |
DE50303336D1 (de) | 2002-05-24 | 2006-06-22 | Schott Ag | Vorrichtung für CVD-Behandlungen |
US20060086320A1 (en) | 2002-05-24 | 2006-04-27 | Michael Lizenberg | Method and device for plasma treating workpieces |
WO2003100129A1 (fr) | 2002-05-24 | 2003-12-04 | Schott Ag | Machine tournante pour application de revetements par depot chimique en phase vapeur |
WO2003099688A1 (fr) | 2002-05-24 | 2003-12-04 | Sig Technology Ltd. | Procede et dispositif pour la manipulation de pieces |
MXPA04011663A (es) | 2002-05-24 | 2005-07-05 | Schott Ag | Dispositivo de recubrimiento multiestaciones y metodo para recubrimiento por plasma. |
AU2003232621A1 (en) | 2002-05-24 | 2003-12-12 | Sig Technology Ltd. | Method and device for plasma treating workpieces |
ATE322561T1 (de) | 2002-05-24 | 2006-04-15 | Schott Ag | Vorrichtung für cvd-beschichtungen |
US7810448B2 (en) | 2002-05-24 | 2010-10-12 | Schott Ag | Apparatus and method for the treating of workpieces |
AU2003229286A1 (en) | 2002-05-24 | 2003-12-12 | Sig Technology Ltd. | Method and device for the plasma treatment of workpieces |
CN2546041Y (zh) | 2002-05-28 | 2003-04-23 | 无锡市宇寿医疗器械有限公司 | 安全自毁式注射器 |
EP2052987B1 (fr) | 2002-05-28 | 2011-08-24 | Kirin Beer Kabushiki Kaisha | Récipient en plastique revêtu de film en DLC |
JP4168671B2 (ja) | 2002-05-31 | 2008-10-22 | 凸版印刷株式会社 | 3次元中空容器の薄膜成膜装置 |
JP3611324B2 (ja) | 2002-06-03 | 2005-01-19 | 信越化学工業株式会社 | マグネトロンプラズマ用磁場発生装置 |
AU2003242357A1 (en) | 2002-06-05 | 2003-12-22 | Kirin Brewery Company, Limited | Method and device for cleaning raw material gas introduction tube used in cvd film forming apparatus |
JP2004008509A (ja) | 2002-06-07 | 2004-01-15 | Terumo Corp | シリンジ用ガスケット、シリンジ及びシリンジ用ガスケットの製造方法 |
US6764714B2 (en) | 2002-06-11 | 2004-07-20 | Southwest Research Institute | Method for depositing coatings on the interior surfaces of tubular walls |
US7052736B2 (en) | 2002-06-11 | 2006-05-30 | Southwest Research Institute | Method for depositing coatings on the interior surfaces of tubular structures |
US20080090425A9 (en) | 2002-06-12 | 2008-04-17 | Christopher Olsen | Two-step post nitridation annealing for lower EOT plasma nitrided gate dielectrics |
JP4080799B2 (ja) | 2002-06-28 | 2008-04-23 | 三井金属鉱業株式会社 | 金属材表面への誘電体フィラー含有ポリイミド被膜の形成方法並びにプリント配線板用のキャパシタ層形成用の銅張積層板の製造方法及びその製造方法で得られた銅張積層板 |
TWI283899B (en) | 2002-07-09 | 2007-07-11 | Applied Materials Inc | Capacitively coupled plasma reactor with magnetic plasma control |
JP4385657B2 (ja) | 2002-07-15 | 2009-12-16 | 凸版印刷株式会社 | 成膜装置および成膜方法 |
KR100390540B1 (ko) | 2002-07-31 | 2003-07-04 | 에이엔 에스 주식회사 | 마그네트론 플라즈마 에칭장치 |
US6995377B2 (en) | 2002-08-02 | 2006-02-07 | Plastipak Packaging, Inc. | Process and apparatus for testing bottles |
US7399500B2 (en) | 2002-08-07 | 2008-07-15 | Schott Ag | Rapid process for the production of multilayer barrier layers |
EP1388594B1 (fr) | 2002-08-07 | 2010-01-06 | Schott Ag | Matériau composite avec une couche barrière lisse et procédé de sa production |
EP1388593B1 (fr) | 2002-08-07 | 2015-12-30 | Schott AG | Méthode rapide de production de revêtements de barrière multicouche |
US7109070B2 (en) | 2002-08-07 | 2006-09-19 | Schot Glas | Production of a composite material having a biodegradable plastic substrate and at least one coating |
EP2284087B1 (fr) | 2002-08-20 | 2017-05-17 | Becton, Dickinson and Company | Methode pour collecter un échantillon |
WO2004019398A1 (fr) | 2002-08-21 | 2004-03-04 | Shin-Etsu Chemical Co., Ltd. | Dispositif servant a generer un champ magnetique mettant en application un magnetron plasmique |
US20040040372A1 (en) | 2002-08-30 | 2004-03-04 | George Plester | Method for determining the permeation of gases into or out of plastic packages and for determination of shelf-life with respect to gas permeation |
US7959866B2 (en) | 2002-09-04 | 2011-06-14 | Becton, Dickinson And Company | Collection assembly |
US6758949B2 (en) | 2002-09-10 | 2004-07-06 | Applied Materials, Inc. | Magnetically confined metal plasma sputter source with magnetic control of ion and neutral densities |
US7015640B2 (en) | 2002-09-11 | 2006-03-21 | General Electric Company | Diffusion barrier coatings having graded compositions and devices incorporating the same |
DE10242086A1 (de) | 2002-09-11 | 2004-04-15 | Sig Technology Ltd. | Behälter zur Verpackung von Produkten, Vorrichtung zur Verarbeitung von Kunstoff sowie Verfahren zur Behälterherstellung |
DE10242698B3 (de) | 2002-09-13 | 2004-03-25 | Fresenius Hemocare Gmbh | Siliziumoxid-beschichtetes Behältnis |
US7713638B2 (en) | 2002-09-14 | 2010-05-11 | Schott Ag | Layer system |
DE10246181A1 (de) | 2002-10-02 | 2004-04-15 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Verfahren und Einrichtung zum plasmaaktivierten Bedampfen von konkav geformten Substraten |
AT413648B (de) | 2002-10-02 | 2006-04-15 | Greiner Bio One Gmbh | Aufnahmevorrichtung mit verstellbarem abdeckelement |
CH707466B1 (de) | 2002-10-03 | 2014-07-15 | Tetra Laval Holdings & Finance | Vorrichtung zur Durchführung eines Plasma-unterstützten Prozesses. |
US6863731B2 (en) | 2002-10-18 | 2005-03-08 | Controls Corporation Of America | System for deposition of inert barrier coating to increase corrosion resistance |
JP2004156444A (ja) | 2002-11-01 | 2004-06-03 | Mitsubishi Heavy Ind Ltd | 遮熱コーティング劣化診断方法 |
WO2004044039A2 (fr) | 2002-11-12 | 2004-05-27 | Dow Global Technologies Inc. | Procede et dispositif permettant de deposer un revetement plasma sur un contenant |
US6965221B2 (en) | 2002-11-12 | 2005-11-15 | O2Micro International Limited | Controller for DC to DC converter |
CN100347229C (zh) | 2002-11-12 | 2007-11-07 | 陶氏环球技术公司 | 在容器中沉积等离子体涂层的方法和设备 |
DE10353540A1 (de) | 2002-11-15 | 2004-05-27 | Laure, Stefan, Dr. | Verfahren und Vorrichtung zum Beschichten von röhrenförmigen Bauteilen |
JP4238015B2 (ja) | 2002-11-19 | 2009-03-11 | 大日本印刷株式会社 | プラスチック製容器の製造法 |
JP3970169B2 (ja) | 2002-11-20 | 2007-09-05 | 三菱商事プラスチック株式会社 | Dlc膜コーティングプラスチック容器の製造方法 |
JP2004200646A (ja) | 2002-12-05 | 2004-07-15 | Advanced Lcd Technologies Development Center Co Ltd | プラズマ処理装置およびプラズマ処理方法 |
US8066854B2 (en) | 2002-12-18 | 2011-11-29 | Metascape Llc | Antimicrobial coating methods |
US7059268B2 (en) | 2002-12-20 | 2006-06-13 | Tokyo Electron Limited | Method, apparatus and magnet assembly for enhancing and localizing a capacitively coupled plasma |
JP2004203682A (ja) | 2002-12-25 | 2004-07-22 | Sumitomo Electric Ind Ltd | 光ファイバプリフォームの製造方法および製造装置 |
US6800852B2 (en) | 2002-12-27 | 2004-10-05 | Revera Incorporated | Nondestructive characterization of thin films using measured basis spectra |
US6891158B2 (en) | 2002-12-27 | 2005-05-10 | Revera Incorporated | Nondestructive characterization of thin films based on acquired spectrum |
US7344832B2 (en) | 2003-01-02 | 2008-03-18 | Bioforce Nanosciences, Inc. | Method and apparatus for molecular analysis in small sample volumes |
US7252651B2 (en) | 2003-01-07 | 2007-08-07 | Becton, Dickinson And Company | Disposable injection device |
AT413947B (de) | 2003-01-27 | 2006-07-15 | Greiner Bio One Gmbh | Medizinische baugruppe sowie eine schutzvorrichtung, ein einstichelement und eine handhabungsvorrichtung für diese baugruppe |
JP2004229750A (ja) | 2003-01-28 | 2004-08-19 | Nipro Corp | プレフィルドシリンジ及びそのバレルの製造方法 |
US6989675B2 (en) | 2003-03-13 | 2006-01-24 | Multimetrixs Llc | Method and apparatus for precision measurement of film thickness |
US7288311B2 (en) | 2003-02-10 | 2007-10-30 | Dai Nippon Printing Co., Ltd. | Barrier film |
JP4233085B2 (ja) | 2003-02-17 | 2009-03-04 | 日本碍子株式会社 | 薄膜作製方法および装置 |
US7303789B2 (en) | 2003-02-17 | 2007-12-04 | Ngk Insulators, Ltd. | Methods for producing thin films on substrates by plasma CVD |
JP2004253683A (ja) | 2003-02-21 | 2004-09-09 | Komatsu Ltd | レジストアウトガス計測装置 |
JP2006519070A (ja) | 2003-02-27 | 2006-08-24 | バクスター・インターナショナル・インコーポレイテッド | 注射器のためのピストンアセンブリ |
JP3699474B2 (ja) | 2003-02-28 | 2005-09-28 | 鹿毛 剛 | プラスチック成形体のガスバリア性測定方法 |
US7332227B2 (en) | 2003-03-14 | 2008-02-19 | Becton, Dickinson And Company | Non-volatile lubricant system for medical devices |
WO2004087247A2 (fr) | 2003-03-25 | 2004-10-14 | Becton, Dickinson And Company | Catheter et ensemble aiguille et procede associe |
US6946164B2 (en) | 2003-03-26 | 2005-09-20 | E.I. Du Pont Nemours And Company | Thin nanometer-controlled polymer film gradient |
EP1630250B1 (fr) | 2003-03-28 | 2013-03-06 | Toyo Seikan Kaisha, Ltd. | Film de depot chimique en phase vapeur forme par un procede cvd a plasma et methode de formation de ce film |
US6864773B2 (en) | 2003-04-04 | 2005-03-08 | Applied Materials, Inc. | Variable field magnet apparatus |
JP4252347B2 (ja) | 2003-04-07 | 2009-04-08 | 三菱商事プラスチック株式会社 | ガスバリア性薄膜コーティングプラスチック容器の製造方法 |
US7972467B2 (en) | 2003-04-17 | 2011-07-05 | Applied Materials Inc. | Apparatus and method to confine plasma and reduce flow resistance in a plasma reactor |
AT500525A1 (de) | 2003-04-17 | 2006-01-15 | Greiner Bio One Gmbh | Aufnahmevorrichtung sowie aus einer dichtungsvorrichtung und kappe gebildete verschlussvorrichtung |
US7431989B2 (en) | 2003-05-06 | 2008-10-07 | Tribofilm Research, Inc. | Article with lubricated surface and method |
KR100509298B1 (ko) | 2003-05-31 | 2005-08-22 | 한국과학기술연구원 | 무기질 박막이 코팅된 직접메탄올 연료전지용 복합고분자 전해질막의 제조 방법 |
JP4202841B2 (ja) | 2003-06-30 | 2008-12-24 | 株式会社Sumco | 表面研磨装置 |
JP2005029855A (ja) | 2003-07-08 | 2005-02-03 | Fuji Electric Device Technology Co Ltd | 真空アーク蒸着装置、真空アーク蒸着法、および磁気記録媒体 |
US20050057754A1 (en) | 2003-07-08 | 2005-03-17 | Smith David E. A. | Measurement of thin film properties using plasmons |
DE10330981B4 (de) | 2003-07-09 | 2010-04-01 | Medion Diagnostics Ag | Vorrichtung und Verfahren zur simultanen Durchführung von Blutgruppenbestimmung, Serumgegenprobe und Antikörpersuch-Test |
JP2005035597A (ja) | 2003-07-14 | 2005-02-10 | Fuji Seal International Inc | プラスチック製容器におけるガスバリア性薄膜の保護方法 |
JP4437647B2 (ja) | 2003-07-17 | 2010-03-24 | 三菱商事プラスチック株式会社 | ガスバリア膜コーティングプラスチック容器の製造方法 |
JP4179941B2 (ja) | 2003-07-24 | 2008-11-12 | 独立行政法人科学技術振興機構 | 薄膜状試料用x線回折測定容器 |
US7189218B2 (en) | 2003-08-07 | 2007-03-13 | Edward Lichtenberg | Needle apparatus with quick/safe release mechanism |
US20050037331A1 (en) | 2003-08-13 | 2005-02-17 | William Galbraith | Apparatuses and methods for reducing albumin in samples |
JP3811150B2 (ja) | 2003-09-05 | 2006-08-16 | 株式会社東芝 | 膜厚測定方法、膜厚測定システム、半導体装置の製造方法及び膜厚測定システム制御プログラム |
US7029803B2 (en) | 2003-09-05 | 2006-04-18 | Schott Ag | Attenuating phase shift mask blank and photomask |
WO2005024518A2 (fr) | 2003-09-05 | 2005-03-17 | Schott Ag | Ebauche de masque a decalage de phase attenue et photomasque |
WO2005028697A1 (fr) | 2003-09-12 | 2005-03-31 | Applied Process Technologies, Inc. | Source de plasma a miroir magnetique et son procede de production |
US7150299B2 (en) | 2003-09-12 | 2006-12-19 | Air Products And Chemicals, Inc. | Assembly and method for containing, receiving and storing fluids and for dispensing gas from a fluid control and gas delivery assembly having an integrated fluid flow restrictor |
US7087437B2 (en) | 2003-09-16 | 2006-08-08 | Vici Gig Harbor Group, Inc. | Direct vial surface sorbent micro extraction device and method |
JP4000373B2 (ja) | 2003-09-26 | 2007-10-31 | 独立行政法人物質・材料研究機構 | イオンの共注入による酸化亜鉛結晶中での硫化亜鉛の合成方法 |
US20070017870A1 (en) | 2003-09-30 | 2007-01-25 | Belov Yuri P | Multicapillary device for sample preparation |
US20050075611A1 (en) | 2003-10-01 | 2005-04-07 | Hetzler Kevin G. | Low extractable, thermoplastic syringe and tip cap |
US20050075612A1 (en) | 2003-10-03 | 2005-04-07 | Baxter International Inc. | Parylene coated fluid flow regulator |
US6844075B1 (en) | 2003-10-06 | 2005-01-18 | General Electric Company | Environmental barrier coating |
JP2005114461A (ja) | 2003-10-06 | 2005-04-28 | Hitachi Industries Co Ltd | 薄膜厚さ測定方法及び装置 |
JP4000374B2 (ja) | 2003-10-10 | 2007-10-31 | 独立行政法人物質・材料研究機構 | 半導体金属酸化物光触媒およびそれを用いた有害化学物質の分解方法 |
DE10347338A1 (de) | 2003-10-11 | 2005-05-19 | Schott Ag | Dünnstsubstrathalter |
US7381311B2 (en) | 2003-10-21 | 2008-06-03 | The United States Of America As Represented By The Secretary Of The Air Force | Filtered cathodic-arc plasma source |
FR2861386B1 (fr) | 2003-10-23 | 2006-02-17 | Saint Gobain | Substrat, notamment substrat verrier, portant une couche a propriete photocatalytique revetue d'une couche mince protectrice. |
JP2005132416A (ja) | 2003-10-30 | 2005-05-26 | Toppan Printing Co Ltd | 酸化珪素薄膜コーティング中空容器 |
US6981403B2 (en) | 2003-10-31 | 2006-01-03 | Mocon, Inc. | Method and apparatus for measuring gas transmission rates of deformable or brittle materials |
DE10351467B4 (de) | 2003-11-04 | 2011-07-07 | Schott Ag, 55122 | Gegenstand mit leicht reinigbarer Oberfläche und Verfahren zu seiner Herstellung |
JP4000375B2 (ja) | 2003-11-19 | 2007-10-31 | 独立行政法人産業技術総合研究所 | 誘導散乱容器 |
US7815864B2 (en) | 2003-11-20 | 2010-10-19 | Sigma-Aldrich Co. | Polysilazane thermosetting polymers for use in chromatographic systems and applications |
KR100802990B1 (ko) | 2003-11-20 | 2008-02-14 | 가부시키가이샤 히다치 고쿠사이 덴키 | 반도체장치의 제조 방법 및 기판처리장치 |
DE10354625A1 (de) | 2003-11-22 | 2005-06-30 | Sig Technology Ltd. | Verfahren zur Bestimmung der Gasdurchlässigkeit von Behälterwandungen, Behälter mit Oberflächenbeschichtung sowie Beschichtungseinrichtung mit Messvorrichtung |
US7513953B1 (en) | 2003-11-25 | 2009-04-07 | Nano Scale Surface Systems, Inc. | Continuous system for depositing films onto plastic bottles and method |
WO2005051525A1 (fr) | 2003-11-25 | 2005-06-09 | Polyvalor, Limited Partnership | Revetement ou couche de protection contre la penetration presentant des proprietes modulees et procedes de fabrication |
JP2005160888A (ja) | 2003-12-05 | 2005-06-23 | Terumo Corp | シリンジ用ガスケット、シリンジ及びシリンジ用ガスケットの製造方法 |
ZA200605822B (en) | 2003-12-16 | 2009-05-27 | Genentech Inc | Novel gene disruptions, compositions and methods relating thereto |
WO2005061222A1 (fr) | 2003-12-22 | 2005-07-07 | Novo Nordisk A/S | Contenant en plastique transparent, souple et impermeable, destine a stocker des liquides pharmaceutiques |
US8110043B2 (en) | 2004-01-08 | 2012-02-07 | University Of Virginia Patent Foundation | Apparatus and method for applying coatings onto the interior surfaces of components and related structures produced therefrom |
DE102004001603B4 (de) | 2004-01-09 | 2009-03-05 | Schott Ag | Behälter mit Innendekor |
JP2005200044A (ja) | 2004-01-14 | 2005-07-28 | Dainippon Printing Co Ltd | プラスチック製容器およびその製造法 |
KR20050076827A (ko) | 2004-01-22 | 2005-07-28 | 쇼오트 아게 | 초 고투과율 위상편이 마스크 블랭크 |
AT500459B1 (de) | 2004-01-23 | 2010-08-15 | Greiner Bio One Gmbh | Verfahren zum zusammenbau einer kappe mit einem aufnahmebehälter |
JP3914925B2 (ja) | 2004-01-28 | 2007-05-16 | 株式会社リガク | 膜厚測定方法及び装置 |
US20070031457A1 (en) | 2004-02-06 | 2007-02-08 | Dubensky Thomas W Jr | Modified Bacillus anthracis, vaccine compositions and methods of use thereof |
CN1946819A (zh) | 2004-02-12 | 2007-04-11 | 瓦尔斯帕供应公司 | 涂覆容器内表面的方法及含有内涂层的容器 |
US7534733B2 (en) | 2004-02-23 | 2009-05-19 | Corning Incorporated | Synthetic silica glass optical material having high resistance to laser induced damage |
JP2005241524A (ja) | 2004-02-27 | 2005-09-08 | Sii Nanotechnology Inc | 走査型プローブ顕微鏡および該顕微鏡による測定方法 |
CN1946874A (zh) | 2004-03-09 | 2007-04-11 | 埃克阿泰克有限责任公司 | 用于非平面基材的等离子体涂覆体系 |
EP1725698A1 (fr) | 2004-03-09 | 2006-11-29 | Exatec, LLC. | Systeme de depot par plasma thermique a expansion |
JP4323991B2 (ja) | 2004-03-19 | 2009-09-02 | 大日本スクリーン製造株式会社 | 分光反射率測定装置、膜厚測定装置および分光反射率測定方法 |
JP2005271997A (ja) | 2004-03-22 | 2005-10-06 | Kazuo Saito | ペットボトルの内壁保護膜 |
DE102004017236B4 (de) | 2004-04-05 | 2012-10-25 | Schott Ag | Verbundmaterial mit verbesserter chemischer Beständigkeit und Verfahren zu dessen Herstellung |
JP4527431B2 (ja) | 2004-04-08 | 2010-08-18 | 東京エレクトロン株式会社 | プラズマ処理装置 |
US20050260504A1 (en) | 2004-04-08 | 2005-11-24 | Hans Becker | Mask blank having a protection layer |
US7378054B2 (en) | 2004-04-16 | 2008-05-27 | Savvipharm Inc | Specimen collecting, processing and analytical assembly |
WO2005103605A1 (fr) | 2004-04-22 | 2005-11-03 | Opo Sprl | Instrument pour mesurer l'epaisseur d'un revetement sur des bouteilles |
US7232038B2 (en) | 2004-04-27 | 2007-06-19 | Whitney Steven G | Disposable test tube rack |
US7867366B1 (en) | 2004-04-28 | 2011-01-11 | Alameda Applied Sciences Corp. | Coaxial plasma arc vapor deposition apparatus and method |
US8038858B1 (en) | 2004-04-28 | 2011-10-18 | Alameda Applied Sciences Corp | Coaxial plasma arc vapor deposition apparatus and method |
US20080131638A1 (en) | 2004-05-04 | 2008-06-05 | Becton, Dickinson And Company | Multilayer barrier containers having increased adhesion and durability |
US7112541B2 (en) | 2004-05-06 | 2006-09-26 | Applied Materials, Inc. | In-situ oxide capping after CVD low k deposition |
WO2006085898A1 (fr) | 2004-05-14 | 2006-08-17 | Becton, Dickinson & Company | Articles presentant des surfaces bioactives et procedes de preparation desdits articles sans solvant |
GB0410749D0 (en) | 2004-05-14 | 2004-06-16 | Dow Corning Ireland Ltd | Coating apparatus |
US7444955B2 (en) | 2004-05-19 | 2008-11-04 | Sub-One Technology, Inc. | Apparatus for directing plasma flow to coat internal passageways |
ATE371470T1 (de) | 2004-05-29 | 2007-09-15 | Gerresheimer Buende Gmbh | Spritzenverschluss und verfahren zum herstellen eines spritzenverschlusses |
DE102004028369B4 (de) | 2004-06-11 | 2007-05-31 | Schott Ag | Verfahren und Vorrichtung zum Behandeln von Substraten in einer Rundläuferanlage |
JP4918857B2 (ja) | 2004-06-11 | 2012-04-18 | 株式会社豊田中央研究所 | 金属酸化物ナノ多孔体、それを得るための被覆組成物、及びそれらの製造方法 |
US7220687B2 (en) | 2004-06-25 | 2007-05-22 | Applied Materials, Inc. | Method to improve water-barrier performance by changing film surface morphology |
US7421885B2 (en) | 2004-06-28 | 2008-09-09 | Air Products And Chemicals, Inc. | Method for characterizing porous low dielectric constant films |
US20060079848A1 (en) | 2004-06-29 | 2006-04-13 | Becton, Dickinson And Company | Non-skin penetrating reconstituting syringe |
US20060079839A1 (en) | 2004-06-29 | 2006-04-13 | Becton, Dickinson And Company | Single-use syringe |
US7246551B2 (en) | 2004-07-09 | 2007-07-24 | Protedyne Corporation | Liquid handling device with surface features at a seal |
US20060014309A1 (en) | 2004-07-13 | 2006-01-19 | Sachdev Krishna G | Temporary chip attach method using reworkable conductive adhesive interconnections |
DE102004034417B4 (de) | 2004-07-15 | 2007-09-27 | Schott Ag | Verfahren zur Herstellung eines beschichteten Substrats mit gewölbter Oberfläche |
DE102004034418B4 (de) | 2004-07-15 | 2009-06-25 | Schott Ag | Verfahren zur Herstellung struktuierter optischer Filterschichten auf Substraten |
US7300684B2 (en) | 2004-07-15 | 2007-11-27 | Sub-One Technology, Inc. | Method and system for coating internal surfaces of prefabricated process piping in the field |
US7118538B2 (en) | 2004-07-19 | 2006-10-10 | Greiner Bio-One Gmbh | Holding device for a medical device |
DE102004035335A1 (de) | 2004-07-21 | 2006-02-16 | Schott Ag | Reinraumfähige Beschichtungsanlage |
DE102004035336A1 (de) | 2004-07-21 | 2006-02-16 | Schott Ag | Reinraumfähige Beschichtungsanlage |
DE102004036170B4 (de) | 2004-07-26 | 2007-10-11 | Schott Ag | Vakuumbeschichtungsanlage und Verfahren zur Vakuumbeschichtung und deren Verwendung |
US7238382B2 (en) | 2004-07-30 | 2007-07-03 | Tokyo Electron Limited | Method and system for characterizing porous materials |
EP1626278A3 (fr) | 2004-08-03 | 2006-06-21 | OnChip Cellomics Consortium | Système de cellomics |
DE102004037542A1 (de) | 2004-08-03 | 2006-02-23 | Chemetall Gmbh | Verfahren zum Schützen einer metallischen Oberfläche mit einer korrosionsinhibierenden Beschichtung |
US7736728B2 (en) | 2004-08-18 | 2010-06-15 | Dow Corning Corporation | Coated substrates and methods for their preparation |
JP2006064416A (ja) | 2004-08-24 | 2006-03-09 | Takeshi Kage | プラスチック成形体のガスバリア性測定方法及びそのガスバリア性測定装置。 |
FR2874606B1 (fr) | 2004-08-26 | 2006-10-13 | Saint Gobain | Procede de transfert d'une molecule organique fonctionnelle sur un substrat transparent |
US20060042755A1 (en) | 2004-08-30 | 2006-03-02 | Plasmamed, Llc | Large surface area dry etcher |
DE102004042431B4 (de) | 2004-08-31 | 2008-07-03 | Schott Ag | Verfahren und Vorrichtung zur Plasmabeschichtung von Werkstücken mit spektraler Auswertung der Prozessparameter und Verwendung der Vorrichtung |
US20060046006A1 (en) | 2004-08-31 | 2006-03-02 | Bastion Bradley J | Multilayer polymeric barrier film, flexible packaging made therewith, and methods |
GB0419772D0 (en) | 2004-09-07 | 2004-10-06 | Scalar Technologies Ltd | Method and apparatus for thin film metrology |
WO2006029387A1 (fr) | 2004-09-09 | 2006-03-16 | Microfluidic Systems Inc. | Dispositif microfluidique manuel et portable servant a la preparation automatique d'acides nucleiques pour analyse |
JP2006083408A (ja) | 2004-09-14 | 2006-03-30 | Shin Meiwa Ind Co Ltd | 真空成膜装置 |
US20070048456A1 (en) | 2004-09-14 | 2007-03-01 | Keshner Marvin S | Plasma enhanced chemical vapor deposition apparatus and method |
DE602005008839D1 (de) | 2004-09-14 | 2008-09-25 | Daikyo Seiko Ltd | Behälter für Medikamente und Gummiverschluss |
US7480363B2 (en) | 2004-09-15 | 2009-01-20 | Ge Betz, Inc. | Converting a digital radiograph to an absolute thickness map |
DE102004045046B4 (de) | 2004-09-15 | 2007-01-04 | Schott Ag | Verfahren und Vorrichtung zum Aufbringen einer elektrisch leitfähigen transparenten Beschichtung auf ein Substrat |
JP4545073B2 (ja) | 2004-09-17 | 2010-09-15 | 三菱重工業株式会社 | ガスバリア膜及び容器 |
EP2436410A1 (fr) | 2004-09-28 | 2012-04-04 | Mallinckrodt LLC | Récipient doté d'un agent de maintien d'une qualité restreinte |
US7648487B2 (en) | 2004-09-28 | 2010-01-19 | Nipro Corporation | Syringe |
FR2876094B1 (fr) | 2004-10-04 | 2009-01-09 | Saint Gobain | Substrat en verre pour ecran de visualisation. |
JP4838255B2 (ja) | 2004-10-05 | 2011-12-14 | ジェンザイム・コーポレーション | 階段状カニューレ |
US7520965B2 (en) | 2004-10-12 | 2009-04-21 | Southwest Research Institute | Magnetron sputtering apparatus and method for depositing a coating using same |
US20060076231A1 (en) | 2004-10-12 | 2006-04-13 | Southwest Research Institute | Method for magnetron sputter deposition |
WO2006044254A1 (fr) | 2004-10-13 | 2006-04-27 | Dow Global Technologies Inc. | Procédé de traitement de surface au plasma |
JP4412661B2 (ja) | 2004-10-15 | 2010-02-10 | 信越化学工業株式会社 | プラズマ処理装置及びプラズマ処理方法 |
JP4171452B2 (ja) | 2004-10-18 | 2008-10-22 | 三菱重工食品包装機械株式会社 | バリア膜形成用内部電極及び成膜装置 |
BE1016251A3 (fr) | 2004-10-27 | 2006-06-06 | Ct Rech Metallurgiques Asbl | Procede ameliore et appareil pour la mesure de l'epaisseur d'une couche d'oxyde. |
DE102004053707B8 (de) | 2004-11-03 | 2008-08-28 | Schott Ag | Verfahren zur Herstellung eines Glaskeramik-Artikels mit Diffusionsbarriere und Verwendung eines verfahrensgemäß hergestellten Glaskeramik-Artikels |
DE102004053708A1 (de) | 2004-11-03 | 2006-05-04 | Schott Ag | Verfahren zur Herstellung eines Erzeugnisses mit Antibeschlag-Beschichtung, sowie verfahrensgemäß herstellbares Erzeugnis |
DE102004053706A1 (de) | 2004-11-03 | 2006-05-04 | Schott Ag | Gegenstand mit Barrierebeschichtung und Verfahren zur Herstellung eines solchen Gegenstandes |
EA010367B1 (ru) | 2004-11-05 | 2008-08-29 | Дау Корнинг Айэлэнд Лимитед | Плазменная система |
AT414322B (de) | 2004-11-29 | 2007-03-15 | Greiner Bio One Gmbh | Trennvorrichtung, insbesondere für körperflüssigkeiten, sowie aufnahmeeinrichtung mit einer derartigen trennvorrichtung |
JP2006153770A (ja) | 2004-11-30 | 2006-06-15 | Omron Corp | 分光計測装置 |
JP4566719B2 (ja) | 2004-12-02 | 2010-10-20 | 麒麟麦酒株式会社 | 炭素膜コーティングプラスチック容器の製造方法、プラズマcvd成膜装置及びそのプラスチック容器 |
US8097725B2 (en) | 2004-12-03 | 2012-01-17 | Roche Diagnostics Operations, Inc. | Luminescent indicator dye and optical sensor |
US7534615B2 (en) | 2004-12-03 | 2009-05-19 | Cryovac, Inc. | Process for detecting leaks in sealed packages |
CN2766863Y (zh) | 2004-12-23 | 2006-03-29 | 许亮 | 无痛注射针 |
CN101091101A (zh) | 2004-12-27 | 2007-12-19 | 新科实业有限公司 | 通过俄歇电子能谱测量纳米薄膜厚度的方法 |
JP2006181027A (ja) | 2004-12-27 | 2006-07-13 | Daikyo Seiko Ltd | 注射器用ピストン |
DE102004063703A1 (de) | 2004-12-28 | 2006-07-06 | Schott Ag | Vakuumbeschichtungssystem |
US7297640B2 (en) | 2005-01-13 | 2007-11-20 | Chartered Semiconductor Manufacturing Ltd. | Method for reducing argon diffusion from high density plasma films |
JP4929727B2 (ja) | 2005-02-14 | 2012-05-09 | 東洋製罐株式会社 | プラズマ処理用ガス供給管 |
US7202564B2 (en) * | 2005-02-16 | 2007-04-10 | International Business Machines Corporation | Advanced low dielectric constant organosilicon plasma chemical vapor deposition films |
JP4515280B2 (ja) | 2005-02-17 | 2010-07-28 | 麒麟麦酒株式会社 | ガスバリア薄膜が成膜されたプラスチック容器の製造装置及びその製造方法 |
US7339682B2 (en) | 2005-02-25 | 2008-03-04 | Verity Instruments, Inc. | Heterodyne reflectometer for film thickness monitoring and method for implementing |
US7608151B2 (en) | 2005-03-07 | 2009-10-27 | Sub-One Technology, Inc. | Method and system for coating sections of internal surfaces |
US7541069B2 (en) | 2005-03-07 | 2009-06-02 | Sub-One Technology, Inc. | Method and system for coating internal surfaces using reverse-flow cycling |
CN101184983A (zh) | 2005-03-16 | 2008-05-21 | 雅拓晶科生物系统(私人)有限公司 | 用于传输、封闭和分析流体样品的方法和装置 |
US20060210425A1 (en) | 2005-03-21 | 2006-09-21 | Laura Mirkarimi | Inorganic coatings for optical and other applications |
US8822272B2 (en) | 2005-03-28 | 2014-09-02 | Semiconductor Energy Laboratory Co., Ltd. | Semiconductor device, manufacturing method thereof, and measuring method thereof |
US7682816B2 (en) | 2005-04-07 | 2010-03-23 | 454 Life Sciences Corporation | Thin film coated microwell arrays and methods of using same |
US7785862B2 (en) | 2005-04-07 | 2010-08-31 | 454 Life Sciences Corporation | Thin film coated microwell arrays |
JP4122011B2 (ja) | 2005-04-15 | 2008-07-23 | 株式会社アルバック | ダイヤモンド状炭素膜の形成方法 |
US8642285B2 (en) | 2005-04-15 | 2014-02-04 | Luxcel Biosciences Limited | Assessment of consumption or release of a gaseous analyte from biological or chemical samples |
EP1715289A1 (fr) | 2005-04-21 | 2006-10-25 | Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno | Procédé à reflection optique lumineuse |
EP1882007B1 (fr) | 2005-05-06 | 2011-12-14 | Dow Global Technologies LLC | Procede de revetement par projection plasma d'un objet en polypropylene |
DE102005023582B4 (de) | 2005-05-18 | 2009-04-16 | Schott Ag | Verfahren zur Herstellung von innenvergüteten Glasrohren |
CH697471B1 (de) * | 2005-05-20 | 2008-10-31 | Tetra Laval Holdings & Finance | Kunststofffilm, Kunststofffolie oder Kunststoffbehà lter mit Barriereschicht. |
WO2006128564A1 (fr) | 2005-05-31 | 2006-12-07 | Baxter International Inc. | Cylindre creux en polypropylene pourvu d'un piston en caoutchouc coulissant |
US20070005024A1 (en) | 2005-06-10 | 2007-01-04 | Jan Weber | Medical devices having superhydrophobic surfaces, superhydrophilic surfaces, or both |
WO2007003502A2 (fr) | 2005-07-01 | 2007-01-11 | Siemens Aktiengesellschaft | Revetement de parylene et procede pour produire un revetement de parylene |
US20070009673A1 (en) | 2005-07-06 | 2007-01-11 | Asm Japan K.K. | Insulation film and method for manufacturing same |
FR2889204B1 (fr) | 2005-07-26 | 2007-11-30 | Sidel Sas | Appareil pour le depot pecvd d'une couche barriere interne sur un recipient, comprenant une ligne de gaz isolee par electrovanne |
US8475886B2 (en) | 2005-08-05 | 2013-07-02 | Corning Incorporated | Methods for producing surfaces that resist non-specific protein binding and cell attachment |
US7745547B1 (en) | 2005-08-05 | 2010-06-29 | Becton, Dickinson And Company | Multi-arm cyclic or cubic siloxane-based formulations for drug delivery |
JP2007050898A (ja) | 2005-08-17 | 2007-03-01 | Toppan Printing Co Ltd | 成膜容器の製造方法およびその製造装置 |
EP1915639B1 (fr) | 2005-08-17 | 2015-10-28 | Siemens Aktiengesellschaft | Procede de determination de l'epaisseur de couche d'un revetement tbc d'au moins une aube d'une turbomachine, dispositif correspondant de mesure de l'epaisseur de couches tbc permettant la mise en oeuvre dudit procede et utilisation de ce procede et de ce dispositif de mesure |
WO2007023292A2 (fr) | 2005-08-24 | 2007-03-01 | Southside Thermal Sciences (Sts) Limited | Systeme et procede, respectivement pour la mesure, le revetement et le controle |
DE102005040266A1 (de) | 2005-08-24 | 2007-03-01 | Schott Ag | Verfahren und Vorrichtung zur innenseitigen Plasmabehandlung von Hohlkörpern |
JP5275543B2 (ja) | 2005-08-31 | 2013-08-28 | 株式会社吉野工業所 | 高いバリア性を有する合成樹脂製容器 |
US20070049048A1 (en) | 2005-08-31 | 2007-03-01 | Shahid Rauf | Method and apparatus for improving nitrogen profile during plasma nitridation |
WO2007089216A1 (fr) | 2005-09-01 | 2007-08-09 | Gorokhovsky Vladimir I | Procédé de dépôt en phase vapeur à plasma et appareil utilisant une commande polarisée bipolaire |
US8786439B2 (en) | 2005-09-02 | 2014-07-22 | Wg Security Products | Active antenna |
KR101263700B1 (ko) | 2005-09-05 | 2013-05-13 | 후쿠와우치 테크놀로지스 가부시키가이샤 | Dlc 제막장치 |
US20070051629A1 (en) | 2005-09-08 | 2007-03-08 | Vladislav Dolnik | Poly(amino saccharide) wall coating for electrophoretic separations in capillaries and microchannels |
EP1941072A2 (fr) | 2005-09-20 | 2008-07-09 | Dow Global Technologies Inc. | Procede de revetement au plasma d'un objet nanocomposite |
JP5103184B2 (ja) | 2005-09-20 | 2012-12-19 | 三菱樹脂株式会社 | ガスバリア性積層フィルム |
FR2891279B1 (fr) | 2005-09-27 | 2007-12-14 | Centre Nat Rech Scient | Nouvelles puces pour la detection par le plasmon de surface (spr) |
AT502522A3 (de) | 2005-10-04 | 2007-12-15 | Greiner Bio One Gmbh | Trennvorrichtung, aufnahmeeinrichtung sowie verfahren zum trennen |
DE102005050432A1 (de) | 2005-10-21 | 2007-05-03 | Rap.Id Particle Systems Gmbh | Vorrichtung und Verfahren zur Charakterisierung von Gleitmittel und Hydrophobierungsfilmen in pharmazeutischen Behältnissen bezüglich Dicke und Homogenität |
US20090117389A1 (en) | 2005-11-07 | 2009-05-07 | Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung | Coating Materials with Oxygen Scavenger and/or Oxygen Indicator Function for Coating or Bonding and Products Produced Therewith |
DE102005058133A1 (de) | 2005-11-30 | 2007-05-31 | Schott Ag | Spritze mit Verschluss |
EP1960279B1 (fr) | 2005-12-01 | 2011-10-19 | CSP Technologies, Inc. | Recipient en forme de bouteille |
US7409313B2 (en) | 2005-12-16 | 2008-08-05 | General Electric Company | Method and apparatus for nondestructive evaluation of insulative coating |
US20070148326A1 (en) | 2005-12-28 | 2007-06-28 | Hastings Mitchell R | Syringe |
KR100730414B1 (ko) | 2005-12-29 | 2007-06-19 | 제일모직주식회사 | 항균 및 대전방지 복합 기능성 하드코팅 조성물, 이의 코팅방법 및 이를 이용한 하드코팅 투명시트 |
US8025915B2 (en) | 2006-01-11 | 2011-09-27 | Schott Ag | Method of preparing a macromolecule deterrent surface on a pharmaceutical package |
US20070168187A1 (en) | 2006-01-13 | 2007-07-19 | Samuel Fletcher | Real time voice analysis and method for providing speech therapy |
US20070166187A1 (en) | 2006-01-18 | 2007-07-19 | Song Jing F | Stabilization of paricalcitol using chlorobutyl or chlorinated butyl stoppers |
EP1987127A4 (fr) | 2006-02-08 | 2011-03-30 | Becton Dickinson Co | Dispositifs de prélèvement et de stockage de spécimen |
US20070184657A1 (en) | 2006-02-09 | 2007-08-09 | Tokyo Electron Limited | Etching method |
US20080045880A1 (en) | 2006-02-11 | 2008-02-21 | Rune Kjeken | Device and method for single-needle in vivo electroporation |
KR101385865B1 (ko) | 2006-02-11 | 2014-04-17 | 제네트로닉스, 인코포레이티드 | 싱글-니들 생체내 일렉트로포레이션용 장치 |
JP2006179948A (ja) | 2006-02-14 | 2006-07-06 | Renesas Technology Corp | 半導体装置の製造方法および半導体装置 |
DE502006001489D1 (de) | 2006-02-14 | 2008-10-16 | Gerresheimer Buende Gmbh | Verfahren zum Herstellen von vorfüllbaren Spritzen |
WO2007095205A2 (fr) | 2006-02-14 | 2007-08-23 | Advanced Electron Beams, Inc. | Emetteur de faisceau electronique |
DE102006009822B4 (de) | 2006-03-01 | 2013-04-18 | Schott Ag | Verfahren zur Plasmabehandlung von Glasoberflächen, dessen Verwendung sowie Glassubstrat und dessen Verwendung |
JP2007231386A (ja) | 2006-03-02 | 2007-09-13 | Toppan Printing Co Ltd | プラズマを使用した容器処理装置 |
US20070205096A1 (en) | 2006-03-06 | 2007-09-06 | Makoto Nagashima | Magnetron based wafer processing |
JP4693120B2 (ja) | 2006-03-15 | 2011-06-01 | 国立大学法人 長崎大学 | 極細長軸体へのコーティング方法および極細長軸体へのコーティング装置 |
WO2007109198A2 (fr) | 2006-03-17 | 2007-09-27 | Applied Process Technologies, Inc. | source de plasma DE miroir ET DE magnétron |
US8545865B2 (en) | 2006-03-24 | 2013-10-01 | Boston Scientific Scimed, Inc. | Medical devices having polymer brushes |
WO2007112328A2 (fr) | 2006-03-24 | 2007-10-04 | University Of Utah Research Foundation | Mesure de l'épaisseur de films diélectriques sur des surfaces |
US8075995B2 (en) | 2006-03-30 | 2011-12-13 | Becton, Dickinson And Company | Coating system, articles and assembly using the same and methods of reducing sticktion |
US7943242B2 (en) | 2006-03-30 | 2011-05-17 | Becton, Dickinson And Company | Sealing members, articles using the same and methods of reducing sticktion |
US8916001B2 (en) | 2006-04-05 | 2014-12-23 | Gvd Corporation | Coated molds and related methods and components |
US20070243618A1 (en) | 2006-04-11 | 2007-10-18 | Oxysense, Inc. | Device and method for non-invasive oxygen sensing of sealed packages |
US20070259184A1 (en) | 2006-05-04 | 2007-11-08 | Commonwealth Scientific And Industrial Research Organisation | Method of mounting objects for chemical vapour deposition |
WO2007133378A1 (fr) | 2006-05-11 | 2007-11-22 | Dow Global Technologies Inc. | Feuille plastique multi-paroi ä revêtement interne obtenu par dépôt chimique en phase vapeur activé par plasma et son procédé de fabrication |
US8273222B2 (en) | 2006-05-16 | 2012-09-25 | Southwest Research Institute | Apparatus and method for RF plasma enhanced magnetron sputter deposition |
DE102006023018A1 (de) | 2006-05-17 | 2007-11-22 | Strämke, Siegfried, Dr. | Plasmaverfahren zur Oberflächenbehandlung von Werkstücken |
AT503747B1 (de) | 2006-05-18 | 2009-05-15 | Greiner Bio One Gmbh | Aufnahmeeinrichtung für eine medizinische vorrichtung |
ITRM20060277A1 (it) | 2006-05-24 | 2007-11-25 | Sipa Societa Industrializzazio | Impianto e processo di verniciatura di contenitori |
US7624622B1 (en) | 2006-05-26 | 2009-12-01 | Mocon, Inc. | Method of measuring the transmission rate of a permeant through a container and determining shelf life of a packaged product within the container |
US7825038B2 (en) | 2006-05-30 | 2010-11-02 | Applied Materials, Inc. | Chemical vapor deposition of high quality flow-like silicon dioxide using a silicon containing precursor and atomic oxygen |
US20070281117A1 (en) | 2006-06-02 | 2007-12-06 | Xtent, Inc. | Use of plasma in formation of biodegradable stent coating |
JP2008000287A (ja) | 2006-06-21 | 2008-01-10 | Terumo Corp | 医療用具コーティング用摺動性組成物および摺動性被膜保有医療用具 |
US7645696B1 (en) | 2006-06-22 | 2010-01-12 | Novellus Systems, Inc. | Deposition of thin continuous PVD seed layers having improved adhesion to the barrier layer |
FR2903622B1 (fr) | 2006-07-17 | 2008-10-03 | Sidel Participations | Dispositif pour le depot d'un revetement sur une face interne d'un recipient |
US8197452B2 (en) | 2006-07-28 | 2012-06-12 | Becton, Dickinson And Company | Vascular access device non-adhering surfaces |
JP5127180B2 (ja) | 2006-07-31 | 2013-01-23 | 株式会社大協精工 | 医療用容器および該医療用容器の処理方法 |
US20080033370A1 (en) | 2006-08-03 | 2008-02-07 | Becton, Dickinson And Company | Binary needle attachment mechanisms |
US7740792B2 (en) | 2006-08-03 | 2010-06-22 | Medrad, Inc. | Methods of molding a syringe |
US20080050932A1 (en) | 2006-08-23 | 2008-02-28 | Applied Materials, Inc. | Overall defect reduction for PECVD films |
DE102006061585B4 (de) | 2006-08-23 | 2013-11-28 | Singulus Technologies Ag | Verfahren und Vorrichtung zur Rotationsbeschichtung von Substraten |
US7552620B2 (en) | 2006-09-07 | 2009-06-30 | 3M Innovative Properties Company | Fluid permeation testing method employing mass spectrometry |
US7555934B2 (en) | 2006-09-07 | 2009-07-07 | 3M Innovative Properties Company | Fluid permeation testing apparatus employing mass spectrometry |
US20080069970A1 (en) | 2006-09-15 | 2008-03-20 | Becton, Dickinson And Company | Medical Components Having Coated Surfaces Exhibiting Low Friction and Methods of Reducing Sticktion |
JP5498790B2 (ja) | 2006-09-15 | 2014-05-21 | ベクトン・ディキンソン・アンド・カンパニー | 低摩擦を示すコーティングされた面を有する医療部品およびスティクションを低下させる方法 |
JP2008086855A (ja) | 2006-09-29 | 2008-04-17 | Fujifilm Corp | 生化学用器具 |
JP5257915B2 (ja) | 2006-09-29 | 2013-08-07 | 国立大学法人東北大学 | 膜塗布装置および膜塗布方法 |
WO2008040531A1 (fr) | 2006-10-05 | 2008-04-10 | Greiner Bio-One Gmbh | Élastomères thermoplastiques contenant des argiles organiques |
US8062266B2 (en) | 2006-10-11 | 2011-11-22 | Becton, Dickinson And Company | Vascular access device including a tear-resistant septum |
DE102006048658B4 (de) | 2006-10-14 | 2014-03-27 | Khs Corpoplast Gmbh | PICVD-Beschichtung für Kunststoffbehälter und Verfahren zu deren Herstellung |
US20080139003A1 (en) | 2006-10-26 | 2008-06-12 | Shahid Pirzada | Barrier coating deposition for thin film devices using plasma enhanced chemical vapor deposition process |
US20080102206A1 (en) | 2006-11-01 | 2008-05-01 | Sigurd Wagner | Multilayered coatings for use on electronic devices or other articles |
EP2096191B1 (fr) | 2006-11-02 | 2015-04-01 | Asahi Glass Company, Limited | Produit moulé en copolymère d'éthylène et de tétrafluoroéthylène et son procédé de production |
EP1918966A1 (fr) | 2006-11-02 | 2008-05-07 | Dow Corning Corporation | Procédé de formation d'une couche à intervalle de bande graduel par déposition d'un matériau amorphe à partir d'un plasma |
US9492596B2 (en) * | 2006-11-06 | 2016-11-15 | Atrium Medical Corporation | Barrier layer with underlying medical device and one or more reinforcing support structures |
DE102006053366A1 (de) | 2006-11-10 | 2008-05-15 | Schott Ag | Verfahren und Vorrichtung zur plasmaunterstützten chemischen Dampfphasenabscheidung |
DE102007037527B4 (de) | 2006-11-10 | 2013-05-08 | Schott Ag | Verfahren zum Beschichten von Gegenständen mit Wechselschichten |
US7780866B2 (en) | 2006-11-15 | 2010-08-24 | Applied Materials, Inc. | Method of plasma confinement for enhancing magnetic control of plasma radial distribution |
US7744567B2 (en) | 2006-11-22 | 2010-06-29 | Becton, Dickinson And Company | Reducing withdrawal force in a safety IV catheter |
US8092605B2 (en) | 2006-11-28 | 2012-01-10 | Applied Materials, Inc. | Magnetic confinement of a plasma |
US8115326B2 (en) | 2006-11-30 | 2012-02-14 | Corning Incorporated | Flexible substrates having a thin-film barrier |
AT504533A1 (de) | 2006-12-05 | 2008-06-15 | Greiner Bio One Gmbh | Probenbehältnis |
DE102006058771B4 (de) | 2006-12-12 | 2018-03-01 | Schott Ag | Behälter mit verbesserter Restentleerbarkeit und Verfahren zu dessen Herstellung |
US7813047B2 (en) | 2006-12-15 | 2010-10-12 | Hand Held Products, Inc. | Apparatus and method comprising deformable lens element |
US20080145271A1 (en) * | 2006-12-19 | 2008-06-19 | Kidambi Srikanth S | Method of using sulfur-based corrosion inhibitors for galvanized metal surfaces |
FR2911071A1 (fr) | 2007-01-09 | 2008-07-11 | Becton Dickinson France Soc Pa | Procede et equipement pour la decontamination par rayonnement d'un produit tel qu'un emballage contenant des dispositifs medicaux. |
CN201002786Y (zh) | 2007-01-12 | 2008-01-09 | 石家庄第一橡胶股份有限公司 | 镀膜瓶塞 |
JP2008174793A (ja) | 2007-01-18 | 2008-07-31 | Nanotec Corp | 成膜装置及び成膜方法。 |
CN101715393B (zh) | 2007-01-29 | 2014-04-30 | 格林科特以色列有限公司 | 制备薄的多金属扩散涂层的方法 |
US20080202414A1 (en) | 2007-02-23 | 2008-08-28 | General Electric Company | Methods and devices for coating an interior surface of a plastic container |
US8409441B2 (en) | 2007-02-27 | 2013-04-02 | Deka Products Limited Partnership | Blood treatment systems and methods |
DE102007011589A1 (de) | 2007-03-08 | 2008-09-11 | Schott Ag | Fördereinrichtung für Precursor |
EP2137338A2 (fr) | 2007-03-28 | 2009-12-30 | Dow Corning Corporation | Procédé de dépôt chimique en phase vapeur amélioré par plasma de rouleau à rouleau de couches barrières comprenant du silicium et du carbone |
US20080260966A1 (en) | 2007-04-22 | 2008-10-23 | Applied Materials, Inc. | Plasma processing method |
US8790312B2 (en) | 2007-04-26 | 2014-07-29 | Daikyo Seiko Ltd. | Needle-equipped syringe barrel and needle-equipped syringe |
US20080277332A1 (en) | 2007-05-11 | 2008-11-13 | Becton, Dickinson And Company | Micromachined membrane filter device for a glaucoma implant and method for making the same |
MY154004A (en) | 2007-05-23 | 2015-04-30 | Southwest Res Inst | Plasma immersion ion processing fro coating of hollow substrates |
US7922880B1 (en) | 2007-05-24 | 2011-04-12 | Novellus Systems, Inc. | Method and apparatus for increasing local plasma density in magnetically confined plasma |
KR20080105617A (ko) | 2007-05-31 | 2008-12-04 | 삼성모바일디스플레이주식회사 | 화학기상증착장치 및 플라즈마강화 화학기상증착장치 |
CN201056331Y (zh) | 2007-05-31 | 2008-05-07 | 许奕新 | 一种带涂层的包装瓶 |
US8723332B2 (en) | 2007-06-11 | 2014-05-13 | Invensas Corporation | Electrically interconnected stacked die assemblies |
KR20080111801A (ko) | 2007-06-20 | 2008-12-24 | 삼성전자주식회사 | 플라즈마 공정장치 및 그 방법 |
EP2173408A1 (fr) | 2007-06-27 | 2010-04-14 | Medingo Ltd. | Tube pour dispositif de distribution de liquide |
US7563425B2 (en) | 2007-06-28 | 2009-07-21 | Korea Advanced Institute Of Science And Technology | Carbonnitride nanotubes with nano-sized pores on their stems, their preparation method and control method of size and quantity of pore thereof |
FR2918301B1 (fr) | 2007-07-06 | 2011-06-24 | Sidel Participations | Revetement barriere depose par plasma comprenant au moins trois couches, procede d'obtention d'un tel revetement et recipient revetu d'un tel revetement |
CH702317B1 (it) | 2007-08-02 | 2011-06-15 | Stevanato Group Internat As | Struttura di confezione di flaconi in vetro ad uso farmaceutico. |
US20100159011A1 (en) | 2007-08-03 | 2010-06-24 | University Of Massachusetts Medical School | Compositions For Biomedical Applications |
US9232618B2 (en) | 2007-08-06 | 2016-01-05 | Immunolight, Llc | Up and down conversion systems for production of emitted light from various energy sources including radio frequency, microwave energy and magnetic induction sources for upconversion |
US8389958B2 (en) | 2009-03-18 | 2013-03-05 | Duke University | Up and down conversion systems for production of emitted light from various energy sources |
CN101785088B (zh) | 2007-08-08 | 2013-06-05 | 株式会社爱发科 | 等离子处理方法和等离子处理装置 |
WO2009021257A1 (fr) | 2007-08-13 | 2009-02-19 | Greiner Bio-One Gmbh | Dispositif médical de séparation |
US20090061237A1 (en) | 2007-08-28 | 2009-03-05 | International Business Machines Corporation | LOW k POROUS SiCOH DIELECTRIC AND INTEGRATION WITH POST FILM FORMATION TREATMENT |
WO2009032117A2 (fr) | 2007-08-31 | 2009-03-12 | Corning Incorporated | Surface réactive sur un substrat polymère |
WO2009030974A1 (fr) | 2007-09-03 | 2009-03-12 | Becton Dickinson France | Dispositif médical et revêtement lubrifiant pour ce dispositif |
WO2009030975A1 (fr) | 2007-09-03 | 2009-03-12 | Becton Dickinson France | Dispositif médical comprenant une chambre siliconée et un moyen de fermeture pourvu d'un revêtement |
WO2009030976A1 (fr) | 2007-09-03 | 2009-03-12 | Becton Dickinson France | Dispositif médical et revêtement lisse pour ce dispositif |
KR100917913B1 (ko) | 2007-09-05 | 2009-09-16 | 한국표준과학연구원 | Cars 현미경을 이용한 유기 박막의 화학종 및 두께동시 광학분석장치 |
US20090069790A1 (en) | 2007-09-07 | 2009-03-12 | Edward Maxwell Yokley | Surface properties of polymeric materials with nanoscale functional coating |
DE102007045455A1 (de) | 2007-09-24 | 2009-04-09 | Schott Ag | Verfahren zur Herstellung von Wafern aus Ingots |
JP5711868B2 (ja) | 2007-09-28 | 2015-05-07 | テルモ株式会社 | 安定なエダラボン含有水性製剤 |
US8231568B2 (en) | 2007-10-16 | 2012-07-31 | Nordson Corporation | Syringes with a reduced susceptibility to freeze-thaw void formation and methods of manufacturing such syringes |
CN106443002A (zh) | 2007-10-22 | 2017-02-22 | 贝克顿·迪金森公司 | 评价在含有机基聚硅氧烷的悬浮液中蛋白质聚集的方法 |
WO2009053947A2 (fr) | 2007-10-22 | 2009-04-30 | Becton Dickinson France | Revêtement de surface pour empêcher la lixiviation cationique |
CN100566764C (zh) | 2007-10-26 | 2009-12-09 | 哈尔滨医科大学 | 一种用于药物涂层血管支架的药物涂层载体及药物涂层血管支架的制备方法 |
US8227025B2 (en) | 2007-11-02 | 2012-07-24 | Gvd Corporation | Conductive polymer coatings and methods of forming the same |
DE102007056240A1 (de) | 2007-11-22 | 2009-05-28 | Henke-Sass, Wolf Gmbh | Spritze |
KR100935976B1 (ko) | 2007-12-07 | 2010-01-08 | 삼성전기주식회사 | 무선랜 시스템에서 다중 목적지 데이터 전송 방법 |
JP5230185B2 (ja) | 2007-12-13 | 2013-07-10 | 富士フイルム株式会社 | 反応性スパッタリング装置および反応性スパッタリングの方法 |
CA2707035A1 (fr) | 2007-12-19 | 2009-09-24 | Ajjer Llc | Procede a haut rendement pour analyse de contamination sur des echantillons preleves dans l'environnement |
DE102007062977B4 (de) | 2007-12-21 | 2018-07-19 | Schott Ag | Verfahren zur Herstellung von Prozessgasen für die Dampfphasenabscheidung |
US8277025B2 (en) | 2008-01-16 | 2012-10-02 | Zamtec Limited | Printhead cartridge with no paper path obstructions |
JP5286553B2 (ja) | 2008-02-05 | 2013-09-11 | 東洋製罐株式会社 | 高周波プラズマ処理装置及び高周波プラズマ処理方法 |
RU2476953C2 (ru) | 2008-03-12 | 2013-02-27 | Алитус Корпорейшн, С.А. | Плазменная система |
US8173221B2 (en) | 2008-03-18 | 2012-05-08 | MCT Research & Development | Protective coatings for metals |
FR2929295A1 (fr) | 2008-03-25 | 2009-10-02 | Becton Dickinson France Soc Pa | Appareil pour le traitement par plasma de corps creux |
JP5463573B2 (ja) | 2008-03-31 | 2014-04-09 | 国立大学法人 琉球大学 | プラズマ生成装置及び方法 |
US20090263668A1 (en) | 2008-04-21 | 2009-10-22 | 3M Innovative Properties Company | Durable coating of an oligomer and methods of applying |
US7632549B2 (en) | 2008-05-05 | 2009-12-15 | Asm Japan K.K. | Method of forming a high transparent carbon film |
JP2011519695A (ja) | 2008-05-08 | 2011-07-14 | リプレニッシュ パンプス, エルエルシー | 植設可能な薬物送達デバイスおよびそのデバイスを充填する装置および方法 |
DE102008023027B4 (de) | 2008-05-09 | 2012-06-28 | Von Ardenne Anlagentechnik Gmbh | Elektrodenanordnung für magnetfeldgeführte plasmagestützte Prozesse im Vakuum |
US8062470B2 (en) | 2008-05-12 | 2011-11-22 | Yuri Glukhoy | Method and apparatus for application of thin coatings from plasma onto inner surfaces of hollow containers |
US7967945B2 (en) | 2008-05-30 | 2011-06-28 | Yuri Glukhoy | RF antenna assembly for treatment of inner surfaces of tubes with inductively coupled plasma |
WO2009158613A1 (fr) | 2008-06-26 | 2009-12-30 | West Pharmaceutical Services, Inc. | Procédé de revêtement de polyxylylène sur des surfaces fluoropolymères et dispositifs ainsi enduits |
US20090326517A1 (en) * | 2008-06-27 | 2009-12-31 | Toralf Bork | Fluidic capillary chip for regulating drug flow rates of infusion pumps |
KR100995700B1 (ko) | 2008-07-14 | 2010-11-22 | 한국전기연구원 | 3차원 표면형상을 갖는 원통형 가공물을 위한 유도 결합형플라즈마 공정 챔버 및 방법 |
US7796844B2 (en) | 2008-07-22 | 2010-09-14 | The Hong Kong Polytechnic University | Temperature-compensated fibre optic strain gauge |
WO2010009724A1 (fr) | 2008-07-25 | 2010-01-28 | Dr. Laure Plasmatechnologie Gmbh | Dispositif pour une application de revêtement assistée par plasma sur le côté intérieur de pièces tubulaires |
US8288513B2 (en) | 2008-07-25 | 2012-10-16 | Becton, Dickinson And Company | Defined cell culturing surfaces and methods of use |
EA020763B9 (ru) | 2008-08-04 | 2015-05-29 | Эй-Джи-Си Флет Гласс Норт Эмерике, Инк. | Источник плазмы и способы нанесения тонкопленочных покрытий с использованием плазменно-химического осаждения из газовой фазы |
DE102008037159A1 (de) | 2008-08-08 | 2010-02-11 | Krones Ag | Vorrichtung und Verfahren zur Plasmabehandlung von Hohlkörpern |
JP5914907B2 (ja) | 2008-08-11 | 2016-05-11 | 株式会社オートネットワーク技術研究所 | 防錆剤および表面処理金属材 |
JP5093686B2 (ja) | 2008-08-27 | 2012-12-12 | 富士電機株式会社 | 磁気記録媒体用保護膜の形成方法 |
ES2731135T3 (es) | 2008-09-22 | 2019-11-14 | Becton Dickinson Co | Sistemas para revestir el interior de un recipiente |
DE102008051614B4 (de) | 2008-10-09 | 2012-09-20 | Schott Ag | Verfahren zur Herstellung von Packmitteln aus Glas für Pharmaprodukte |
US9018098B2 (en) | 2008-10-23 | 2015-04-28 | Lam Research Corporation | Silicon etch with passivation using chemical vapor deposition |
WO2010047825A1 (fr) | 2008-10-24 | 2010-04-29 | Gvd Corporation | Procédés de revêtement, systèmes et articles associés |
US20100104770A1 (en) | 2008-10-27 | 2010-04-29 | Asm Japan K.K. | Two-step formation of hydrocarbon-based polymer film |
JP5012762B2 (ja) | 2008-10-30 | 2012-08-29 | 大日本印刷株式会社 | プラスチック製容器の製造法 |
JP5012761B2 (ja) | 2008-10-30 | 2012-08-29 | 大日本印刷株式会社 | プラスチック製容器の製造法 |
WO2010065564A1 (fr) * | 2008-12-02 | 2010-06-10 | Georgia Tech Research Corporation | Revêtement de protection contre l'environnement pour dispositifs à semi-conducteurs organiques et procédés associés |
DE102008062881B4 (de) | 2008-12-16 | 2021-04-08 | Schott Ag | Verfahren zur Herstellung eines hohlen Glasformkörpers |
US20100174245A1 (en) | 2009-01-08 | 2010-07-08 | Ward Dean Halverson | System for pretreating the lumen of a catheter |
US20100190036A1 (en) | 2009-01-27 | 2010-07-29 | Kyriakos Komvopoulos | Systems and Methods for Surface Modification by Filtered Cathodic Vacuum Arc |
EP2218465A1 (fr) | 2009-02-02 | 2010-08-18 | KHS GmbH | Appareil pour stériliser un récipient |
US8574203B2 (en) | 2009-02-11 | 2013-11-05 | Becton, Dickinson And Company | Systems and methods for providing a flushable catheter assembly |
US8469928B2 (en) | 2009-02-11 | 2013-06-25 | Becton, Dickinson And Company | Systems and methods for providing a flushable catheter assembly |
US8388583B2 (en) | 2009-08-20 | 2013-03-05 | Becton, Dickinson And Company | Systems and methods for providing a flushable catheter assembly |
US8679063B2 (en) | 2009-02-11 | 2014-03-25 | Becton, Dickinson And Company | Systems and methods for providing a catheter assembly |
KR101660557B1 (ko) | 2009-02-18 | 2016-09-27 | 카운슬 오브 사이언티픽 앤드 인더스트리얼 리서치 | 성형 물품의 내부 표면 상에 보호 코팅으로서 다이아몬드상 카본을 증착하는 방법 |
DE102009011960B4 (de) | 2009-03-10 | 2013-06-13 | Schott Ag | Verfahren zur Überwachung von Plasma-Entladungen |
KR20100104119A (ko) | 2009-03-16 | 2010-09-29 | 삼성전자주식회사 | 박막 형성 장치 및 그의 박막 형성 방법 |
US8197910B2 (en) | 2009-04-27 | 2012-06-12 | Becton, Dickinson And Company | Methods for producing synthetic surfaces that mimic collagen coated surfaces for cell culture |
FR2944982B1 (fr) | 2009-04-30 | 2011-10-14 | Commissariat Energie Atomique | Procede de preparation d'un substrat metallise,ledit substrat et ses utilisations |
MX345403B (es) | 2009-05-13 | 2017-01-30 | Sio2 Medical Products Inc | Revestimiento por pecvd utilizando un precursor organosilícico. |
JP2012526922A (ja) | 2009-05-13 | 2012-11-01 | エスアイオーツー・メディカル・プロダクツ・インコーポレイテッド | 有機ケイ素前駆体を使用するpecvd被覆材 |
US7985188B2 (en) | 2009-05-13 | 2011-07-26 | Cv Holdings Llc | Vessel, coating, inspection and processing apparatus |
SG176008A1 (en) | 2009-05-13 | 2011-12-29 | Cv Holdings Llc | Pecvd coating using an organosilicon precursor |
KR20100126208A (ko) | 2009-05-21 | 2010-12-01 | 조지아 테크 리서치 코포레이션 | 항미생물성 자외선 역변환 조성물 |
US9458536B2 (en) | 2009-07-02 | 2016-10-04 | Sio2 Medical Products, Inc. | PECVD coating methods for capped syringes, cartridges and other articles |
FR2948177B1 (fr) | 2009-07-16 | 2011-08-05 | Inst Francais Du Petrole | Procede de combustion en boucle chimique avec controle independant de la circulation des solides |
JP5373905B2 (ja) | 2009-07-17 | 2013-12-18 | 株式会社アルバック | 成膜装置及び成膜方法 |
KR20110020186A (ko) | 2009-08-21 | 2011-03-02 | 한양대학교 산학협력단 | 고분자 전해질형 연료 전지용 고분자 전해질 막, 이의 제조 방법 및 이를 포함하는 고분자 전해질형 연료 전지 시스템 |
JP2011060885A (ja) | 2009-09-08 | 2011-03-24 | Tokyo Electron Ltd | プラズマ処理装置及びプラズマ処理方法 |
DE102009041132B4 (de) | 2009-09-14 | 2014-08-14 | Schott Ag | Verfahren zur Herstellung einer Gleitschicht und pharmazeutisches Packmittel mit Gleitschicht |
US20110065798A1 (en) | 2009-09-17 | 2011-03-17 | Becton, Dickinson And Company | Anti-infective lubricant for medical devices and methods for preparing the same |
EP2480271A2 (fr) | 2009-09-22 | 2012-08-01 | Medmix Systems AG | Contenant scellé pourvu d'un piston coulissant |
CN102725202B (zh) | 2009-10-09 | 2015-03-25 | 西氏制药服务德国有限公司及两合公司 | 具有阻挡层的弹性封罩及其制造方法 |
US9597458B2 (en) | 2009-10-29 | 2017-03-21 | W. L. Gore & Associates, Inc. | Fluoropolymer barrier materials for containers |
EP3556412B1 (fr) | 2009-10-29 | 2021-04-14 | W.L. Gore & Associates Inc. | Piston de seringue revêtu d'eptfe |
US20110111132A1 (en) | 2009-11-09 | 2011-05-12 | Electric Power Research Institute, Inc. | System and method for depositing coatings on inner surface of tubular structure |
JP5357710B2 (ja) | 2009-11-16 | 2013-12-04 | 東京エレクトロン株式会社 | 基板処理方法,基板処理装置,プログラムを記録した記録媒体 |
US20110152820A1 (en) | 2009-12-22 | 2011-06-23 | Medtronic Minimed, Inc. | Barrier coatings for fluids contacting medical devices |
FR2954326B1 (fr) | 2009-12-23 | 2013-01-18 | Valois Sas | Procede de traitement de surface d'un dispositif de distribution de produit fluide. |
WO2011090717A1 (fr) | 2009-12-28 | 2011-07-28 | Gvd Corporation | Procédés de revêtement, systèmes et articles apparentés |
WO2011082296A1 (fr) | 2009-12-31 | 2011-07-07 | Surmodics, Inc. | Polymères hydrophiles à modification d'ester silylique et utilisations pour articles médicaux |
WO2011080543A1 (fr) | 2009-12-31 | 2011-07-07 | Becton Dickinson France | Composants médicaux à surfaces revêtues présentant un frottement réduit et/ou une faible perméabilité au gaz/liquide |
JP6150523B2 (ja) | 2010-02-05 | 2017-06-21 | デカ・プロダクツ・リミテッド・パートナーシップ | 注入ポンプ装置、方法およびシステム |
US8747631B2 (en) | 2010-03-15 | 2014-06-10 | Southwest Research Institute | Apparatus and method utilizing a double glow discharge plasma for sputter cleaning |
JP5226031B2 (ja) | 2010-04-13 | 2013-07-03 | テルモ株式会社 | 薬剤収容容器 |
EP2381246A1 (fr) | 2010-04-26 | 2011-10-26 | Becton Dickinson France | Dispositif, kit et procédé pour inspection d'un article |
JP2013525013A (ja) | 2010-04-30 | 2013-06-20 | バイエル ファーマ アクチエンゲゼルシャフト | 置換式シリンジ |
EP3437743A1 (fr) | 2010-05-12 | 2019-02-06 | SiO2 Medical Products, Inc. | Seringue avec revêtement à pouvoir lubrifiant |
WO2011148718A1 (fr) | 2010-05-28 | 2011-12-01 | 太陽化学工業株式会社 | Pochoir de sérigraphie ayant des films de carbone amorphe et procédé de fabrication de ce dernier |
US8802603B2 (en) | 2010-06-17 | 2014-08-12 | Becton, Dickinson And Company | Medical components having coated surfaces exhibiting low friction and low reactivity |
WO2011161044A1 (fr) | 2010-06-22 | 2011-12-29 | Novo Nordisk A/S | Récipient médical protégé contre les fissures |
US8628475B2 (en) | 2010-06-24 | 2014-01-14 | Cdw Investments, Llc | Hyperechogenic needles |
WO2012003221A1 (fr) | 2010-06-29 | 2012-01-05 | Cv Holdings, Llc | Seringue dotée d'une aiguille intégrée |
US9475225B2 (en) | 2010-07-16 | 2016-10-25 | SiO2 Medical Produts, Inc. | Injection molding process and product produced using the same |
US20120021136A1 (en) | 2010-07-20 | 2012-01-26 | Varian Semiconductor Equipment Associates, Inc. | System and method for controlling plasma deposition uniformity |
US8623324B2 (en) | 2010-07-21 | 2014-01-07 | Aat Bioquest Inc. | Luminescent dyes with a water-soluble intramolecular bridge and their biological conjugates |
US9145874B2 (en) | 2010-08-09 | 2015-09-29 | Msnw Llc | Apparatus, systems and methods for establishing plasma and using plasma in a rotating magnetic field |
US8932259B2 (en) | 2010-09-13 | 2015-01-13 | Becton, Dickinson And Company | Catheter assembly |
IT1402399B1 (it) | 2010-10-21 | 2013-09-04 | Protec Surface Technologies S R L | Canna perfezionata. |
US8773020B2 (en) | 2010-10-22 | 2014-07-08 | Applied Materials, Inc. | Apparatus for forming a magnetic field and methods of use thereof |
US8476162B2 (en) | 2010-10-27 | 2013-07-02 | Applied Materials, Inc. | Methods of forming layers on substrates |
UA97584C2 (ru) | 2010-11-08 | 2012-02-27 | Национальный Научный Центр "Харьковский Физико-Технический Институт" | СПОСОБ ТРАНСПОРТИРОВКИ Вакуумно-дуговой Катодной ПЛАЗМЫ С фильтрованием От макрочастиц И УСТРОЙСТВО ДЛЯ ЕГО ОСУЩЕСТВЛЕНИЯ |
US9878101B2 (en) | 2010-11-12 | 2018-01-30 | Sio2 Medical Products, Inc. | Cyclic olefin polymer vessels and vessel coating methods |
US8921516B2 (en) | 2010-12-08 | 2014-12-30 | Corning Incorporated | Synthetic, defined fibronectin mimetic peptides and surfaces modified with the same |
DE102010055155A1 (de) | 2010-12-15 | 2012-06-21 | Khs Corpoplast Gmbh | Verfahren zur Plasmabehandlung von Werkstücken sowie Werkstück mit Gasbarriereschicht |
JP2012149278A (ja) | 2011-01-17 | 2012-08-09 | Mitsui Chemicals Inc | シリコン含有膜の製造方法 |
CN103703085B (zh) | 2011-01-19 | 2016-09-28 | 哈佛学院院长等 | 光滑注液多孔表面和其生物学应用 |
DE102011009057B4 (de) | 2011-01-20 | 2015-12-10 | Schott Ag | Plasma-Behandlungsvorrichtung zur Herstellung von Beschichtungen und Verfahren zur innenseitigen Plasmabehandlung von Behältern |
EP2683836B1 (fr) | 2011-03-10 | 2021-02-17 | Kaiatech, Inc. | Procédé et appareil de traitement de contenants |
JP5801586B2 (ja) | 2011-03-31 | 2015-10-28 | テルモ株式会社 | 脂肪乳剤プレフィルドシリンジ製剤 |
US9272095B2 (en) | 2011-04-01 | 2016-03-01 | Sio2 Medical Products, Inc. | Vessels, contact surfaces, and coating and inspection apparatus and methods |
US8871319B2 (en) | 2011-04-12 | 2014-10-28 | The Procter & Gamble Company | Flexible barrier packaging derived from renewable resources |
DE102011076754A1 (de) | 2011-05-31 | 2012-12-06 | Schott Ag | Substratelement für die Beschichtung mit einer Easy-to-clean Beschichtung |
US20140190846A1 (en) | 2011-07-29 | 2014-07-10 | Dsm Ip Assets B.V | Medical device comprising a wetted hydrophilic coating |
US20130046375A1 (en) | 2011-08-17 | 2013-02-21 | Meng Chen | Plasma modified medical devices and methods |
US10388493B2 (en) | 2011-09-16 | 2019-08-20 | Lam Research Corporation | Component of a substrate support assembly producing localized magnetic fields |
CN103957966B (zh) | 2011-09-27 | 2017-09-29 | 贝克顿迪金森法国公司 | 等离子体处理过的硅油作为医用注射装置中的涂层的用途 |
FR2980789B1 (fr) | 2011-09-29 | 2013-10-25 | Commissariat Energie Atomique | Procede de fabrication d'un objet a partir d'une solution sol-gel |
SE1250261A1 (sv) | 2011-10-31 | 2013-05-01 | Billerudkorsnaes Gaevle Froevi Ab | Bestrykningskomposition, ett förfarande för bestrykning av ett substrat, ettbestruket substrat, ett förpackningsmaterial och vätskeförpackning |
EP2776603B1 (fr) | 2011-11-11 | 2019-03-06 | SiO2 Medical Products, Inc. | Revêtement de passivation, de protection de ph ou à pouvoir lubrifiant pour conditionnement pharmaceutique, processus et appareil de revêtement |
FR2982914B1 (fr) | 2011-11-22 | 2014-01-17 | Snecma | Propulseur a effet de hall |
JP2013116289A (ja) | 2011-12-05 | 2013-06-13 | Daikyo Seiko Ltd | 医薬品用注射器 |
EP2602354A1 (fr) | 2011-12-05 | 2013-06-12 | Pivot a.s. | Appareil et procédé de dépôt sous vide par arc cathodique filtré et procédé |
CN104254579B (zh) | 2012-01-10 | 2018-05-29 | 哈佛学院院长等 | 用于流体和固体排斥性的表面的改性 |
DE102012201955A1 (de) | 2012-02-09 | 2013-08-14 | Krones Ag | Powerlanze und plasmaunterstützte Beschichtung mit Hochfrequenzeinkopplung |
CN102581274B (zh) | 2012-03-08 | 2014-06-11 | 中国工程物理研究院化工材料研究所 | 一种化学气相沉积包覆微纳米金属粉的方法 |
US9068565B2 (en) | 2012-05-03 | 2015-06-30 | Becton, Dickinson And Company | Container and method for storing a pharmaceutical agent |
JP5899044B2 (ja) | 2012-05-08 | 2016-04-06 | 三菱樹脂株式会社 | ガスバリア性フィルム |
CA2887352A1 (fr) | 2012-05-09 | 2013-11-14 | Sio2 Medical Products, Inc. | Enrobage protecteur en saccharide pour conditionnement pharmaceutique |
CA2887367A1 (fr) | 2012-05-09 | 2013-11-14 | Sio2 Medical Products, Inc. | Procedes d'inspection pour des revetements pecvd |
US9993597B2 (en) | 2012-05-29 | 2018-06-12 | Becton Dickinson France | Lubricant coating and medical injection device comprising such a coating |
AU2013269594C1 (en) | 2012-06-01 | 2020-12-17 | Novartis Ag | Syringe |
US9034442B2 (en) | 2012-11-30 | 2015-05-19 | Corning Incorporated | Strengthened borosilicate glass containers with improved damage tolerance |
JP6488232B2 (ja) | 2012-07-03 | 2019-03-20 | エスアイオーツー・メディカル・プロダクツ・インコーポレイテッド | 薬剤パッケージのSiOxバリア及び被覆プロセス |
JOP20200175A1 (ar) | 2012-07-03 | 2017-06-16 | Novartis Ag | حقنة |
US9133412B2 (en) | 2012-07-09 | 2015-09-15 | Tribofilm Research, Inc. | Activated gaseous species for improved lubrication |
WO2014012078A2 (fr) | 2012-07-13 | 2014-01-16 | President And Fellows Of Harvard College | Surfaces de transport et de mouillage sélectifs |
US9630224B2 (en) | 2012-07-13 | 2017-04-25 | President And Fellows Of Harvard College | Slippery liquid-infused porous surfaces having improved stability |
EP2872574A1 (fr) | 2012-07-13 | 2015-05-20 | President and Fellows of Harvard College | Surface slips à base de composé contenant un métal |
CA2879732A1 (fr) | 2012-07-20 | 2014-01-23 | Lbp Manufacturing, Inc. | Chauffage par micro-ondes de materiaux thermo-expansibles servant a fabriquer des substrats et produits d'encapsulation |
TWI501441B (zh) | 2012-08-24 | 2015-09-21 | Ind Tech Res Inst | 非連續複合阻障層、其形成方法及包含其之封裝結構 |
FR2994851B1 (fr) | 2012-09-04 | 2015-08-21 | Rexam Healthcare La Verpillier | Dispositif d'injection de liquide pharmaceutique configure pour etre pre-rempli |
WO2014059012A1 (fr) | 2012-10-12 | 2014-04-17 | Sio2 Medical Products, Inc. | Procédé pour le revêtement intérieur de corps creux |
EP2914762B1 (fr) | 2012-11-01 | 2020-05-13 | SiO2 Medical Products, Inc. | Procédé d'inspection de revêtement |
US9903782B2 (en) | 2012-11-16 | 2018-02-27 | Sio2 Medical Products, Inc. | Method and apparatus for detecting rapid barrier coating integrity characteristics |
US10117806B2 (en) | 2012-11-30 | 2018-11-06 | Corning Incorporated | Strengthened glass containers resistant to delamination and damage |
WO2014085348A2 (fr) | 2012-11-30 | 2014-06-05 | Sio2 Medical Products, Inc. | Contrôle de l'uniformité de dépôt chimique en phase vapeur activé par plasma (pecvd) sur des seringues médicales, des cartouches et analogues |
US9662450B2 (en) | 2013-03-01 | 2017-05-30 | Sio2 Medical Products, Inc. | Plasma or CVD pre-treatment for lubricated pharmaceutical package, coating process and apparatus |
KR102472240B1 (ko) | 2013-03-11 | 2022-11-30 | 에스아이오2 메디컬 프로덕츠, 인크. | 코팅된 패키징 |
WO2014144926A1 (fr) | 2013-03-15 | 2014-09-18 | Sio2 Medical Products, Inc. | Procédé de revêtement |
DE102013103676A1 (de) | 2013-04-11 | 2014-10-30 | Schott Ag | Behälter mit geringer Partikelemission und reibkontrollierter Trockengleitoberfläche, sowie Verfahren zu dessen Herstellung |
JP6274213B2 (ja) | 2013-08-07 | 2018-02-07 | コニカミノルタ株式会社 | ガスバリア性フィルム |
JP6317086B2 (ja) | 2013-10-02 | 2018-04-25 | 住友ゴム工業株式会社 | プレフィルドシリンジ用ガスケット |
JP2017531812A (ja) | 2014-10-06 | 2017-10-26 | ゼブラシー インコーポレイテッド | 注射筒潤滑被覆の品質管理 |
DE102014223398A1 (de) | 2014-11-17 | 2016-05-19 | Henkel Ag & Co. Kgaa | Mittel und Verfahren zur temporären Verformung keratinhaltiger Fasern |
US10765811B2 (en) | 2014-12-08 | 2020-09-08 | Genentech, Inc. | Versatile syringe platform |
JP6289401B2 (ja) | 2015-02-24 | 2018-03-07 | 沖電気工業株式会社 | スポットサイズ変換器 |
WO2016135755A1 (fr) | 2015-02-27 | 2016-09-01 | Mylan Laboratories Limited | Aprémilast amorphe, pré-mélanges correspondant et nouvelles formes cristallines d'aprémilast |
JP7041579B2 (ja) | 2018-04-19 | 2022-03-24 | 文化シヤッター株式会社 | シャッター装置のシャッターカーテン施工装置及びその施工方法 |
JP7068614B2 (ja) | 2018-09-24 | 2022-05-17 | 株式会社ニコン | エンコーダ、駆動装置、ロボット装置、制御システム及びその制御方法 |
JP7126419B2 (ja) | 2018-09-26 | 2022-08-26 | 株式会社エクセディ | 動力伝達装置 |
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US11709156B2 (en) | 2017-09-18 | 2023-07-25 | Waters Technologies Corporation | Use of vapor deposition coated flow paths for improved analytical analysis |
US11918936B2 (en) | 2020-01-17 | 2024-03-05 | Waters Technologies Corporation | Performance and dynamic range for oligonucleotide bioanalysis through reduction of non specific binding |
Also Published As
Publication number | Publication date |
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JP6095678B2 (ja) | 2017-03-15 |
US11724860B2 (en) | 2023-08-15 |
EP2776603A1 (fr) | 2014-09-17 |
CN103930595A (zh) | 2014-07-16 |
US10577154B2 (en) | 2020-03-03 |
US10189603B2 (en) | 2019-01-29 |
US20230150727A1 (en) | 2023-05-18 |
WO2013071138A1 (fr) | 2013-05-16 |
US11148856B2 (en) | 2021-10-19 |
CA2855353A1 (fr) | 2013-05-16 |
US11884446B2 (en) | 2024-01-30 |
AU2012318242A1 (en) | 2013-05-30 |
US20150021339A1 (en) | 2015-01-22 |
EP2776603A4 (fr) | 2015-08-19 |
US20190233167A1 (en) | 2019-08-01 |
US20220161969A1 (en) | 2022-05-26 |
JP2014533177A (ja) | 2014-12-11 |
US20200270025A1 (en) | 2020-08-27 |
EP2776603B1 (fr) | 2019-03-06 |
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