ATE91716T1 - Verfahren zur herstellung vielkettige polypeptide oder proteine. - Google Patents

Verfahren zur herstellung vielkettige polypeptide oder proteine.

Info

Publication number
ATE91716T1
ATE91716T1 AT84301996T AT84301996T ATE91716T1 AT E91716 T1 ATE91716 T1 AT E91716T1 AT 84301996 T AT84301996 T AT 84301996T AT 84301996 T AT84301996 T AT 84301996T AT E91716 T1 ATE91716 T1 AT E91716T1
Authority
AT
Austria
Prior art keywords
host cell
processes
proteins
transformed
production
Prior art date
Application number
AT84301996T
Other languages
English (en)
Inventor
Michael Alan Boss
John Henry Kenten
John Spencer Emtage
Clive Ross Wood
Original Assignee
Celltech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10540204&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE91716(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Celltech Ltd filed Critical Celltech Ltd
Application granted granted Critical
Publication of ATE91716T1 publication Critical patent/ATE91716T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46Hybrid immunoglobulins
    • C07K16/461Igs containing Ig-regions, -domains or -residues form different species
    • C07K16/462Igs containing a variable region (Fv) from one specie and a constant region (Fc) from another
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B01D15/3804Affinity chromatography
    • B01D15/3809Affinity chromatography of the antigen-antibody type, e.g. protein A, G, L chromatography
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT84301996T 1983-03-25 1984-03-23 Verfahren zur herstellung vielkettige polypeptide oder proteine. ATE91716T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB838308235A GB8308235D0 (en) 1983-03-25 1983-03-25 Polypeptides
EP84301996A EP0120694B2 (de) 1983-03-25 1984-03-23 Verfahren zur Herstellung von Immunglobulinen

Publications (1)

Publication Number Publication Date
ATE91716T1 true ATE91716T1 (de) 1993-08-15

Family

ID=10540204

Family Applications (1)

Application Number Title Priority Date Filing Date
AT84301996T ATE91716T1 (de) 1983-03-25 1984-03-23 Verfahren zur herstellung vielkettige polypeptide oder proteine.

Country Status (7)

Country Link
US (1) US4816397A (de)
EP (2) EP0120694B2 (de)
JP (4) JP2594900B2 (de)
AT (1) ATE91716T1 (de)
DE (1) DE3486179T3 (de)
GB (2) GB8308235D0 (de)
WO (1) WO1984003712A2 (de)

Families Citing this family (1950)

* Cited by examiner, † Cited by third party
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EP0120694B1 (de) 1993-07-21
DE3486179D1 (de) 1993-08-26
EP0120694A2 (de) 1984-10-03
JP3186463B2 (ja) 2001-07-11
EP0120694B2 (de) 2002-04-24
GB2137631A (en) 1984-10-10
GB2137631B (en) 1986-11-12
JPH07173200A (ja) 1995-07-11
WO1984003712A2 (en) 1984-09-27
DE3486179T2 (de) 1993-11-04
JP2001286291A (ja) 2001-10-16
EP0120694A3 (en) 1985-07-03
JPH1080296A (ja) 1998-03-31
GB8407571D0 (en) 1984-05-02
US4816397A (en) 1989-03-28
WO1984003712A3 (en) 1984-11-22
GB8308235D0 (en) 1983-05-05
JP2594900B2 (ja) 1997-03-26
JPS60500892A (ja) 1985-06-20
EP0526953A1 (de) 1993-02-10
DE3486179T3 (de) 2004-03-04

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