DE69839553D1 - Verfahren zur herstellung von proteinen - Google Patents
Verfahren zur herstellung von proteinenInfo
- Publication number
- DE69839553D1 DE69839553D1 DE69839553T DE69839553T DE69839553D1 DE 69839553 D1 DE69839553 D1 DE 69839553D1 DE 69839553 T DE69839553 T DE 69839553T DE 69839553 T DE69839553 T DE 69839553T DE 69839553 D1 DE69839553 D1 DE 69839553D1
- Authority
- DE
- Germany
- Prior art keywords
- methods
- host cells
- present
- proteins
- polypeptides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/24—Extraction; Separation; Purification by electrochemical means
- C07K1/26—Electrophoresis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/13—Labelling of peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
- C12N9/0036—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Electrochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3465897P | 1997-01-08 | 1997-01-08 | |
PCT/US1998/000492 WO1998030684A1 (en) | 1997-01-08 | 1998-01-08 | Methods for production of proteins |
Publications (1)
Publication Number | Publication Date |
---|---|
DE69839553D1 true DE69839553D1 (de) | 2008-07-10 |
Family
ID=21877792
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69839553T Expired - Lifetime DE69839553D1 (de) | 1997-01-08 | 1998-01-08 | Verfahren zur herstellung von proteinen |
Country Status (8)
Country | Link |
---|---|
US (8) | US6703484B2 (de) |
EP (3) | EP2336313A1 (de) |
JP (2) | JP2001512306A (de) |
AT (1) | ATE397061T1 (de) |
AU (1) | AU6020998A (de) |
DE (1) | DE69839553D1 (de) |
ES (1) | ES2308800T3 (de) |
WO (1) | WO1998030684A1 (de) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69839553D1 (de) | 1997-01-08 | 2008-07-10 | Invitrogen Corp | Verfahren zur herstellung von proteinen |
JP3432158B2 (ja) * | 1998-12-04 | 2003-08-04 | 日立ソフトウエアエンジニアリング株式会社 | 電気泳動方法、電気泳動装置及びそれに用いるマーカー試料 |
WO2001002588A2 (en) * | 1999-07-02 | 2001-01-11 | Morphosys Ag | Generation of specific binding partners binding to (poly)peptides encoded by genomic dna fragments or ests |
US20030157720A1 (en) * | 2002-02-06 | 2003-08-21 | Expression Technologies Inc. | Protein standard for estimating size and mass |
CA2485835C (en) | 2002-05-24 | 2018-03-06 | Restoragen, Inc. | Methods and dna constructs for high yield production of polypeptides |
EP1572720A4 (de) * | 2002-05-24 | 2008-12-24 | Nps Allelix Corp | Verfahren zur enzymatischen herstellung von glp-2-(1-33)- und glp-2-(1-34)-peptiden |
AU2003231862A1 (en) * | 2002-05-24 | 2003-12-12 | Restoragen, Inc. | Methods and dna constructs for high yield production of polypeptides |
DE10244502B4 (de) * | 2002-09-25 | 2006-06-01 | Universität Gesamthochschule Kassel | Molekulargewichtsmarker für Proteine und Verfahren zu dessen Herstellung |
WO2004035169A2 (en) * | 2002-10-15 | 2004-04-29 | The Regents Of The University Of Michigan | Multidimensional protein separation system |
WO2004072236A2 (en) * | 2003-02-06 | 2004-08-26 | The Board Of Trustees Of The University Of Illinois | Methods and compositions for 3-d sodium dodecyl sulfate-polyacrylamide cube gel electrophoresis |
US7781173B2 (en) | 2003-09-25 | 2010-08-24 | Life Technologies Corporation | Homogeneous populations of molecules |
EP1704234B1 (de) * | 2003-11-21 | 2012-01-18 | NPS Pharmaceuticals, Inc. | Herstellung von glucagonähnlichem peptid 2 und analogen |
US20050202405A1 (en) | 2003-11-28 | 2005-09-15 | Amshey Joseph W. | Methods, compositions, and kits for protein crystallization |
WO2005114220A2 (en) * | 2004-05-17 | 2005-12-01 | Invitrogen Corporation | Compositions, kits, and methods for calibration in mass spectrometry |
US8728759B2 (en) * | 2004-10-04 | 2014-05-20 | National Research Council Of Canada | Reverse cumate repressor mutant |
US7935788B2 (en) * | 2004-10-04 | 2011-05-03 | National Research Council Of Canada | Reverse cumate repressor mutant |
WO2006096704A2 (en) | 2005-03-07 | 2006-09-14 | Invitrogen Corporation | Isotopically-labeled proteome standards |
WO2008042495A2 (en) * | 2006-07-21 | 2008-04-10 | Life Technologies Corporation | Sharply resolving labeled protein molecular weight standards |
US7951559B2 (en) * | 2007-07-25 | 2011-05-31 | E.I. Du Pont De Nemours And Company | Recombinant peptide production using a cross-linkable solubility tag |
GB0718012D0 (en) * | 2007-09-14 | 2007-10-24 | Lab901 Ltd | Method for protein staining prior to electrophoresis |
KR101016766B1 (ko) | 2009-01-15 | 2011-02-25 | 한국과학기술연구원 | 티오레독신이 융합된 단백질 발현용 플라스미드 및 이를 이용한 목적 단백질의 생산방법 |
WO2011151721A1 (en) * | 2010-06-04 | 2011-12-08 | Lupin Limited | Process for production of fusion proteins using truncated e. coli thioredoxin |
WO2012149180A2 (en) | 2011-04-26 | 2012-11-01 | Life Technologies Corporation | Fluorescent tracking dye |
CN104471395B (zh) | 2012-06-28 | 2017-05-03 | 生物辐射实验室股份有限公司 | 多重蛋白质定量标准物 |
CN105143860B (zh) | 2013-03-14 | 2019-03-08 | 生物辐射实验室股份有限公司 | 蛋白质标准品 |
US9663554B2 (en) * | 2014-09-19 | 2017-05-30 | Li-Cor, Inc. | Multifunctional protein molecular weight ladders |
US11124555B2 (en) | 2017-01-27 | 2021-09-21 | Abera Bioscience Ab | Fusion polypeptides comprising one or more inclusion body tags, methods and uses |
Family Cites Families (87)
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---|---|---|---|---|
US3980540A (en) * | 1975-03-28 | 1976-09-14 | Hoefer Scientific Instruments | Vertical gel slab electrophoresis apparatus and method |
JPS5292590A (en) | 1976-01-30 | 1977-08-04 | Oriental Yeast Co Ltd | Isoelectric point marker for separation of isoelectric points of gel |
US4403036A (en) | 1980-12-02 | 1983-09-06 | University Of Iowa Research Foundation | Genetic reagents for generating plasmids containing multiple copies of DNA segments |
US4405720A (en) * | 1981-03-04 | 1983-09-20 | The United States Of America As Represented By The Department Of Health And Human Services | Silver stains for protein in gels |
US4507233A (en) | 1981-04-22 | 1985-03-26 | Oriental Yeast Co., Ltd. | Colored molecular weight marker |
US4499782A (en) | 1981-10-05 | 1985-02-19 | National Research Development Corporation | Transmission units of the toroidal race rolling friction type |
US4468466A (en) | 1982-02-16 | 1984-08-28 | The United States Of America As Represented By The Department Of Health And Human Services | Silver stains for protein in gels--a modified procedure |
SE8300693L (sv) | 1983-02-09 | 1984-08-10 | Sven Lofdahl | Sett att framstella och isolera proteiner och polypeptider samt en hybridvektor for detta |
US4518584A (en) | 1983-04-15 | 1985-05-21 | Cetus Corporation | Human recombinant interleukin-2 muteins |
US5279792A (en) | 1984-06-22 | 1994-01-18 | Janssen Pharmaceutica N.V. | Staining kit for proteins and nucleic acids |
GB8415998D0 (en) | 1984-06-22 | 1984-07-25 | Janssen Pharmaceutica Nv | Staining method |
US4791069A (en) | 1984-09-21 | 1988-12-13 | Ortho Diagnostic Systems Inc. | Methods for attaching ligands or anti-ligands to a solid phase |
US4575452A (en) | 1984-09-21 | 1986-03-11 | E. I. Du Pont De Nemours And Company | Kit for silver staining proteins and nucleic acids |
US4569794A (en) | 1984-12-05 | 1986-02-11 | Eli Lilly And Company | Process for purifying proteins and compounds useful in such process |
SE459503B (sv) | 1985-05-03 | 1989-07-10 | Excorim Kommanditbolag | Hybrid-dna-molekyl innefattande dna-sekvens som kodar foer protein g samt foerfarande foer framstaellning av protein g |
US4766224A (en) * | 1985-08-19 | 1988-08-23 | International Minerals & Chemical Corp. | Purification and activation of proteins from insoluble inclusion bodies |
US4677196A (en) * | 1985-09-06 | 1987-06-30 | International Minerals & Chemical Corp. | Purification and activation of proteins from insoluble inclusion bodies |
US5082773A (en) * | 1986-02-14 | 1992-01-21 | Pharmacia Lkb Biotechnology Ab | Cloned streptococcal genes encoding protein G and their use to construct recombinant microorganisms to produce protein G |
US4782027A (en) * | 1987-01-22 | 1988-11-01 | President And Fellows Of Harvard College | Protein detection by negative staining |
US5643758A (en) * | 1987-03-10 | 1997-07-01 | New England Biolabs, Inc. | Production and purification of a protein fused to a binding protein |
US5215896A (en) | 1987-03-20 | 1993-06-01 | Creative Biomolecules, Inc. | Leader sequences for the production of recombinant proteins |
DE3884529T2 (de) | 1987-03-20 | 1994-04-28 | Creative Biomolecules Inc | Leader-anteile zur produktion von rekombinanten proteinen. |
US6150503A (en) * | 1988-10-28 | 2000-11-21 | Pestka Biomedical Laboratories, Inc. | Phosphorylated fusion proteins |
EP0413440B1 (de) * | 1989-07-19 | 1995-08-09 | Tonen Corporation | Peptidyl prolyl-cis, trans-Isomerase |
US5594115A (en) | 1990-04-09 | 1997-01-14 | Pharmacia & Upjohn Company | Process of purifying recombinant proteins and compounds useful in such process |
US5316908A (en) * | 1990-07-13 | 1994-05-31 | Life Technologies, Inc. | Size markers for electrophoretic analysis of DNA |
US5595887A (en) | 1990-07-16 | 1997-01-21 | Bionebraska, Inc. | Purification directed cloning of peptides using carbonic anhydrase as the affinity binding segment |
US5273906A (en) * | 1990-11-19 | 1993-12-28 | Promega Corporation | Protein staining compositions and methods |
US5132439A (en) | 1990-11-19 | 1992-07-21 | Promega Corporation | Protein staining compositions and methods |
US5714326A (en) * | 1991-01-24 | 1998-02-03 | Dawson; Elliott P. | Method for the multiplexed preparation of nucleic acid molecular weight markers and resultant products |
US5292646A (en) * | 1991-02-06 | 1994-03-08 | Genetics Institute, Inc. | Peptide and protein fusions to thioredoxin and thioredoxin-like molecules |
US5270181A (en) | 1991-02-06 | 1993-12-14 | Genetics Institute, Inc. | Peptide and protein fusions to thioredoxin and thioredoxin-like molecules |
JPH04271800A (ja) * | 1991-02-28 | 1992-09-28 | Hitachi Ltd | 電気泳動装置 |
US5139630A (en) * | 1991-05-31 | 1992-08-18 | Beckman Instruments, Inc. | Identification of sample constituents utilizing capillary electrophoresis |
US6060296A (en) | 1991-07-03 | 2000-05-09 | The Salk Institute For Biological Studies | Protein kinases |
EP0863210A3 (de) | 1991-07-25 | 1999-09-22 | Oriental Yeast Co., Ltd. | Künstliches Immunglobulinkombinierendes Protein |
KR100242093B1 (ko) | 1991-09-20 | 2000-02-01 | 그레고리 아보트 | 신경교 유도 신경 영양성 인자 |
DK1023900T3 (da) * | 1991-11-14 | 2005-06-06 | Brigham & Womens Hospital | Farmaceutisk præparat indeholdende S-nitroso-lipoproteiner og anvendelse deraf |
ATE227307T1 (de) * | 1992-04-07 | 2002-11-15 | Scripps Research Inst | Verfahren zur herstellung modifizierten proteine |
US5439812A (en) | 1992-04-08 | 1995-08-08 | The Pennsylvania Research Corporation | Antibodies catalyzing deamidation of proteins |
US5705649A (en) * | 1992-07-20 | 1998-01-06 | Promega Corporation | Protein staining compositions and methods |
EP0655890B1 (de) * | 1992-07-31 | 2005-01-26 | AB Enzymes GmbH | Rekombinante zelle, dna-konstruktionen, vektoren und methoden zur expression von phytatabbauenden enzymen in gewünschten verhältnissen |
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KR100260632B1 (ko) * | 1992-12-28 | 2000-07-01 | 성재갑 | 이식형 소마토트로핀 조성물 |
US5801005A (en) | 1993-03-17 | 1998-09-01 | University Of Washington | Immune reactivity to HER-2/neu protein for diagnosis of malignancies in which the HER-2/neu oncogene is associated |
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ES2118534T3 (es) * | 1993-10-28 | 1998-09-16 | Life Technologies Inc | Escalera de marcadores de acido nucleico para estimacion de la masa. |
US6680378B1 (en) * | 1993-10-28 | 2004-01-20 | Invitrogen Corporation | Nucleic acid marker ladder for estimating mass |
US5449758A (en) | 1993-12-02 | 1995-09-12 | Life Technologies, Inc. | Protein size marker ladder |
DE69533544T2 (de) | 1994-01-11 | 2006-02-23 | Dyax Corp., Cambridge | Inhibitoren des humanplasmins, die sich von den kunitz domänen ableiten |
US5578180A (en) | 1994-03-31 | 1996-11-26 | Novel Experimental Technology | System for PH-neutral longlife precast electrophoresis gel |
US5643722A (en) * | 1994-05-11 | 1997-07-01 | Trustees Of Boston University | Methods for the detection and isolation of proteins |
US5891993A (en) * | 1994-08-11 | 1999-04-06 | The Scripps Research Institute | Template assembled synthetic protein |
US5541087A (en) | 1994-09-14 | 1996-07-30 | Fuji Immunopharmaceuticals Corporation | Expression and export technology of proteins as immunofusins |
EP0796335A1 (de) | 1994-12-07 | 1997-09-24 | Bionebraska, Inc. | Herstellung von peptiden mittles rekombinanter fusionsprotein-konstruktionen |
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AU711451B2 (en) | 1995-05-04 | 1999-10-14 | Scripps Research Institute, The | Synthesis of proteins by native chemical ligation |
US6184344B1 (en) | 1995-05-04 | 2001-02-06 | The Scripps Research Institute | Synthesis of proteins by native chemical ligation |
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JP2004506221A (ja) | 2000-08-11 | 2004-02-26 | インヴィトロジェン コーポレーション | 高度に均一な電気泳動用分子マーカー |
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WO2006138366A2 (en) | 2005-06-16 | 2006-12-28 | New England Biolabs, Inc. | Protein markers |
WO2008042495A2 (en) | 2006-07-21 | 2008-04-10 | Life Technologies Corporation | Sharply resolving labeled protein molecular weight standards |
-
1998
- 1998-01-08 DE DE69839553T patent/DE69839553D1/de not_active Expired - Lifetime
- 1998-01-08 WO PCT/US1998/000492 patent/WO1998030684A1/en active Application Filing
- 1998-01-08 AT AT98903438T patent/ATE397061T1/de not_active IP Right Cessation
- 1998-01-08 US US09/004,068 patent/US6703484B2/en not_active Expired - Lifetime
- 1998-01-08 ES ES98903438T patent/ES2308800T3/es not_active Expired - Lifetime
- 1998-01-08 EP EP10174765A patent/EP2336313A1/de not_active Withdrawn
- 1998-01-08 AU AU60209/98A patent/AU6020998A/en not_active Abandoned
- 1998-01-08 EP EP98903438A patent/EP0963435B1/de not_active Expired - Lifetime
- 1998-01-08 EP EP09180307A patent/EP2196536A1/de not_active Withdrawn
- 1998-01-08 JP JP53117798A patent/JP2001512306A/ja not_active Ceased
-
2003
- 2003-12-08 US US10/728,766 patent/US7223566B2/en not_active Expired - Fee Related
-
2006
- 2006-01-11 US US11/329,401 patent/US7259242B2/en not_active Expired - Fee Related
- 2006-01-11 US US11/329,418 patent/US7265206B2/en not_active Expired - Fee Related
- 2006-12-29 US US11/618,725 patent/US8389681B2/en not_active Expired - Fee Related
- 2006-12-29 US US11/618,723 patent/US8012715B2/en not_active Expired - Fee Related
-
2007
- 2007-11-29 JP JP2007308538A patent/JP4791436B2/ja not_active Expired - Lifetime
-
2011
- 2011-01-13 US US13/006,354 patent/US8519099B2/en not_active Expired - Fee Related
-
2013
- 2013-07-25 US US13/951,285 patent/US9409942B2/en not_active Expired - Fee Related
Also Published As
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US20060269992A1 (en) | 2006-11-30 |
JP2001512306A (ja) | 2001-08-21 |
ATE397061T1 (de) | 2008-06-15 |
EP2196536A1 (de) | 2010-06-16 |
US7265206B2 (en) | 2007-09-04 |
JP4791436B2 (ja) | 2011-10-12 |
EP0963435B1 (de) | 2008-05-28 |
WO1998030684A1 (en) | 1998-07-16 |
US20020065392A1 (en) | 2002-05-30 |
US20040204563A1 (en) | 2004-10-14 |
US7223566B2 (en) | 2007-05-29 |
US20070190606A1 (en) | 2007-08-16 |
US20060286633A1 (en) | 2006-12-21 |
US8389681B2 (en) | 2013-03-05 |
ES2308800T3 (es) | 2008-12-01 |
JP2008119000A (ja) | 2008-05-29 |
US8012715B2 (en) | 2011-09-06 |
US20070184527A1 (en) | 2007-08-09 |
US8519099B2 (en) | 2013-08-27 |
AU6020998A (en) | 1998-08-03 |
EP0963435A4 (de) | 2004-09-22 |
US7259242B2 (en) | 2007-08-21 |
US20110108420A1 (en) | 2011-05-12 |
EP2336313A1 (de) | 2011-06-22 |
US6703484B2 (en) | 2004-03-09 |
US9409942B2 (en) | 2016-08-09 |
EP0963435A1 (de) | 1999-12-15 |
US20140097086A1 (en) | 2014-04-10 |
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