SE8300693L - Sett att framstella och isolera proteiner och polypeptider samt en hybridvektor for detta - Google Patents

Sett att framstella och isolera proteiner och polypeptider samt en hybridvektor for detta

Info

Publication number
SE8300693L
SE8300693L SE8300693A SE8300693A SE8300693L SE 8300693 L SE8300693 L SE 8300693L SE 8300693 A SE8300693 A SE 8300693A SE 8300693 A SE8300693 A SE 8300693A SE 8300693 L SE8300693 L SE 8300693L
Authority
SE
Sweden
Prior art keywords
polypeptide
protein
fusion protein
igg
host
Prior art date
Application number
SE8300693A
Other languages
Unknown language ( )
English (en)
Other versions
SE8300693D0 (sv
Inventor
Sven Lofdahl
Mathias Uhlen
Martin Lindberg
John Sjoquist
Original Assignee
Sven Lofdahl
Mathias Uhlen
Martin Lindberg
John Sjoquist
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sven Lofdahl, Mathias Uhlen, Martin Lindberg, John Sjoquist filed Critical Sven Lofdahl
Priority to SE8300693A priority Critical patent/SE8300693L/sv
Publication of SE8300693D0 publication Critical patent/SE8300693D0/sv
Priority to JP59500885A priority patent/JPH0634742B2/ja
Priority to EP84900773A priority patent/EP0135532B1/en
Priority to AT84900773T priority patent/ATE36348T1/de
Priority to DE8484900773T priority patent/DE3473298D1/de
Priority to PCT/SE1984/000046 priority patent/WO1984003103A1/en
Publication of SE8300693L publication Critical patent/SE8300693L/sv
Priority to US07/196,846 priority patent/US5100788A/en
Priority to JP7117618A priority patent/JPH07265078A/ja

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/65—Insulin-like growth factors (Somatomedins), e.g. IGF-1, IGF-2
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/66—General methods for inserting a gene into a vector to form a recombinant vector using cleavage and ligation; Use of non-functional linkers or adaptors, e.g. linkers containing the sequence for a restriction endonuclease
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/036—Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/61—Fusion polypeptide containing an enzyme fusion for detection (lacZ, luciferase)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/705—Fusion polypeptide containing domain for protein-protein interaction containing a protein-A fusion
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
SE8300693A 1983-02-09 1983-02-09 Sett att framstella och isolera proteiner och polypeptider samt en hybridvektor for detta SE8300693L (sv)

Priority Applications (8)

Application Number Priority Date Filing Date Title
SE8300693A SE8300693L (sv) 1983-02-09 1983-02-09 Sett att framstella och isolera proteiner och polypeptider samt en hybridvektor for detta
JP59500885A JPH0634742B2 (ja) 1983-02-09 1984-02-09 蛋白質とポリペプチドを製造及び分離する方法
EP84900773A EP0135532B1 (en) 1983-02-09 1984-02-09 Method of producing and selectively isolating proteins and polypeptides, recombinant and expression vector therefor and fusion protein able to bind to the constant region of immunoglobulins
AT84900773T ATE36348T1 (de) 1983-02-09 1984-02-09 Herstellungsverfahren und selektive isolierung von proteinen und polypeptiden, rekombinant und expressionsvektor dazu und schmelzprotein das zum konstanten teil von immoglobulinen binden kann.
DE8484900773T DE3473298D1 (en) 1983-02-09 1984-02-09 Method of producing and selectively isolating proteins and polypeptides, recombinant and expression vector therefor and fusion protein able to bind to the constant region of immunoglobulins
PCT/SE1984/000046 WO1984003103A1 (en) 1983-02-09 1984-02-09 Method of producing and selectively isolating proteins and polypeptides, recombinant and expression vector therefor and fusion protein able to bind to the constant region of immunoglobulins
US07/196,846 US5100788A (en) 1983-02-09 1988-05-09 Method of producing and isolating igg-binding protein a fusion peptides and a vector therefor
JP7117618A JPH07265078A (ja) 1983-02-09 1995-04-20 蛋白質とポリペプチドを製造するための組換えベクター

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8300693A SE8300693L (sv) 1983-02-09 1983-02-09 Sett att framstella och isolera proteiner och polypeptider samt en hybridvektor for detta

Publications (2)

Publication Number Publication Date
SE8300693D0 SE8300693D0 (sv) 1983-02-09
SE8300693L true SE8300693L (sv) 1984-08-10

Family

ID=20349966

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8300693A SE8300693L (sv) 1983-02-09 1983-02-09 Sett att framstella och isolera proteiner och polypeptider samt en hybridvektor for detta

Country Status (6)

Country Link
US (1) US5100788A (sv)
EP (1) EP0135532B1 (sv)
JP (2) JPH0634742B2 (sv)
DE (1) DE3473298D1 (sv)
SE (1) SE8300693L (sv)
WO (1) WO1984003103A1 (sv)

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Also Published As

Publication number Publication date
EP0135532A1 (en) 1985-04-03
SE8300693D0 (sv) 1983-02-09
JPS60500480A (ja) 1985-04-11
JPH0634742B2 (ja) 1994-05-11
US5100788A (en) 1992-03-31
EP0135532B1 (en) 1988-08-10
JPH07265078A (ja) 1995-10-17
WO1984003103A1 (en) 1984-08-16
DE3473298D1 (en) 1988-09-15

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