MX2023007028A - Composiciones de proteínas y métodos para producir y usar las mismas. - Google Patents
Composiciones de proteínas y métodos para producir y usar las mismas.Info
- Publication number
- MX2023007028A MX2023007028A MX2023007028A MX2023007028A MX2023007028A MX 2023007028 A MX2023007028 A MX 2023007028A MX 2023007028 A MX2023007028 A MX 2023007028A MX 2023007028 A MX2023007028 A MX 2023007028A MX 2023007028 A MX2023007028 A MX 2023007028A
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- producing
- same
- compositions
- protein compositions
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 4
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 title abstract 2
- 239000000427 antigen Substances 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 238000004113 cell culture Methods 0.000 abstract 1
- 238000001742 protein purification Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/18—Ion-exchange chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
- C07K16/065—Purification, fragmentation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/32—Bonded phase chromatography
- B01D15/325—Reversed phase
- B01D15/327—Reversed phase with hydrophobic interaction
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
- B01D15/3804—Affinity chromatography
- B01D15/3809—Affinity chromatography of the antigen-antibody type, e.g. protein A, G, L chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente invención se refiere a composiciones que comprenden una proteína, por ejemplo, un anticuerpo, o una porción de unión a antígeno del mismo, por ejemplo, un anticuerpo anti-GM-CSFRa o una porción de unión a antígeno del mismo, y métodos, por ejemplo, métodos de cultivo de células y/o purificación de proteínas, para producir tales composiciones. También se proporcionan métodos para usar tales composiciones para tratar un trastorno, por ejemplo, un trastorno asociado a GM-CSFR.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063127973P | 2020-12-18 | 2020-12-18 | |
| PCT/US2021/063995 WO2022133191A2 (en) | 2020-12-18 | 2021-12-17 | Protein compositions and methods for producing and using the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2023007028A true MX2023007028A (es) | 2023-09-21 |
Family
ID=80168227
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2023007028A MX2023007028A (es) | 2020-12-18 | 2021-12-17 | Composiciones de proteínas y métodos para producir y usar las mismas. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20220281914A1 (es) |
| EP (1) | EP4263597A2 (es) |
| JP (1) | JP2024500747A (es) |
| KR (1) | KR20230132470A (es) |
| CN (1) | CN117043181A (es) |
| AU (1) | AU2021401316A1 (es) |
| CA (1) | CA3202339A1 (es) |
| MX (1) | MX2023007028A (es) |
| WO (1) | WO2022133191A2 (es) |
Family Cites Families (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USRE30985E (en) | 1978-01-01 | 1982-06-29 | Serum-free cell culture media | |
| US4399216A (en) | 1980-02-25 | 1983-08-16 | The Trustees Of Columbia University | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US4634665A (en) | 1980-02-25 | 1987-01-06 | The Trustees Of Columbia University In The City Of New York | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US5179017A (en) | 1980-02-25 | 1993-01-12 | The Trustees Of Columbia University In The City Of New York | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US4510245A (en) | 1982-11-18 | 1985-04-09 | Chiron Corporation | Adenovirus promoter system |
| US4560655A (en) | 1982-12-16 | 1985-12-24 | Immunex Corporation | Serum-free cell culture medium and process for making same |
| US4657866A (en) | 1982-12-21 | 1987-04-14 | Sudhir Kumar | Serum-free, synthetic, completely chemically defined tissue culture media |
| GB8308235D0 (en) | 1983-03-25 | 1983-05-05 | Celltech Ltd | Polypeptides |
| US4534972A (en) | 1983-03-29 | 1985-08-13 | Miles Laboratories, Inc. | Protein compositions substantially free from infectious agents |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| DD266710A3 (de) | 1983-06-06 | 1989-04-12 | Ve Forschungszentrum Biotechnologie | Verfahren zur biotechnischen Herstellung van alkalischer Phosphatase |
| US4767704A (en) | 1983-10-07 | 1988-08-30 | Columbia University In The City Of New York | Protein-free culture medium |
| US4879231A (en) | 1984-10-30 | 1989-11-07 | Phillips Petroleum Company | Transformation of yeasts of the genus pichia |
| US5168062A (en) | 1985-01-30 | 1992-12-01 | University Of Iowa Research Foundation | Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence |
| GB8516415D0 (en) | 1985-06-28 | 1985-07-31 | Celltech Ltd | Culture of animal cells |
| US4968615A (en) | 1985-12-18 | 1990-11-06 | Ciba-Geigy Corporation | Deoxyribonucleic acid segment from a virus |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| US4927762A (en) | 1986-04-01 | 1990-05-22 | Cell Enterprises, Inc. | Cell culture medium with antioxidant |
| GB8610600D0 (en) | 1986-04-30 | 1986-06-04 | Novo Industri As | Transformation of trichoderma |
| US5476996A (en) | 1988-06-14 | 1995-12-19 | Lidak Pharmaceuticals | Human immune system in non-human animal |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| ATE135397T1 (de) | 1988-09-23 | 1996-03-15 | Cetus Oncology Corp | Zellenzuchtmedium für erhöhtes zellenwachstum, zur erhöhung der langlebigkeit und expression der produkte |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| EP0402226A1 (en) | 1989-06-06 | 1990-12-12 | Institut National De La Recherche Agronomique | Transformation vectors for yeast yarrowia |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| JPH06508511A (ja) | 1990-07-10 | 1994-09-29 | ケンブリッジ アンティボディー テクノロジー リミティド | 特異的な結合ペアーの構成員の製造方法 |
| US5122469A (en) | 1990-10-03 | 1992-06-16 | Genentech, Inc. | Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins |
| WO1992009690A2 (en) | 1990-12-03 | 1992-06-11 | Genentech, Inc. | Enrichment method for variant proteins with altered binding properties |
| DK1279731T3 (da) | 1991-03-01 | 2007-09-24 | Dyax Corp | Fremgangsmåde til udvikling af bindende miniproteiner |
| DK1471142T3 (da) | 1991-04-10 | 2009-03-09 | Scripps Research Inst | Heterodimere receptor-biblioteker under anvendelse af fagemider |
| DE4122599C2 (de) | 1991-07-08 | 1993-11-11 | Deutsches Krebsforsch | Phagemid zum Screenen von Antikörpern |
| US6090382A (en) | 1996-02-09 | 2000-07-18 | Basf Aktiengesellschaft | Human antibodies that bind human TNFα |
| US6914128B1 (en) | 1999-03-25 | 2005-07-05 | Abbott Gmbh & Co. Kg | Human antibodies that bind human IL-12 and methods for producing |
| KR100583331B1 (ko) | 2001-05-11 | 2006-05-26 | 기린 비루 가부시키가이샤 | 인간 항체 λ 경쇄 유전자를 포함하는 인간 인공 염색체 및 자손 전달 가능한 상기 인간 인공 염색체를 포함하는 비인간 동물 |
| AU2003234090A1 (en) | 2002-04-11 | 2003-10-27 | Medimmune Vaccines, Inc. | Spray freeze dry of compositions for pulmonary administration |
| KR20050011741A (ko) | 2002-04-11 | 2005-01-29 | 메드이뮨 백신즈 인코포레이티드 | 분무 건조에 의한 생물학적 활성 물질의 보존 |
| CA2849556A1 (en) | 2002-04-11 | 2003-10-23 | Vu Truong-Le | Preservation of bioactive materials by freeze dried foam |
| WO2003086443A1 (en) | 2002-04-11 | 2003-10-23 | Medimmune Vaccines, Inc. | Spray freeze dry of compositions for intranasal administration |
| EP1581639A4 (en) | 2002-12-17 | 2006-03-08 | Medimmune Vaccines Inc | HIGH PRESSURE PULVISATION OF BIOACTIVE MATERIALS |
| CN103641916A (zh) | 2006-03-27 | 2014-03-19 | 医学免疫有限公司 | Gm-csf受体结合元件 |
| WO2013158275A1 (en) * | 2012-04-20 | 2013-10-24 | Abbvie Inc. | Cell culture methods to reduce acidic species |
| JP7290725B2 (ja) * | 2018-11-27 | 2023-06-13 | 舒泰神（北京）生物製薬股フン有限公司 | 顆粒球－マクロファージコロニー刺激因子受容体αを特異的に認識する抗体及びその使用 |
| JP7375027B2 (ja) * | 2019-02-14 | 2023-11-07 | メルス ナムローゼ フェンノートシャップ | ２つ以上の抗体を含む組成物の製造 |
-
2021
- 2021-12-17 MX MX2023007028A patent/MX2023007028A/es unknown
- 2021-12-17 JP JP2023536940A patent/JP2024500747A/ja active Pending
- 2021-12-17 KR KR1020237024236A patent/KR20230132470A/ko unknown
- 2021-12-17 CN CN202180093700.8A patent/CN117043181A/zh active Pending
- 2021-12-17 US US17/554,659 patent/US20220281914A1/en active Pending
- 2021-12-17 EP EP21852094.8A patent/EP4263597A2/en active Pending
- 2021-12-17 WO PCT/US2021/063995 patent/WO2022133191A2/en active Application Filing
- 2021-12-17 CA CA3202339A patent/CA3202339A1/en active Pending
- 2021-12-17 AU AU2021401316A patent/AU2021401316A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2021401316A9 (en) | 2023-08-24 |
| KR20230132470A (ko) | 2023-09-15 |
| AU2021401316A1 (en) | 2023-07-06 |
| CN117043181A (zh) | 2023-11-10 |
| JP2024500747A (ja) | 2024-01-10 |
| CA3202339A1 (en) | 2022-06-23 |
| WO2022133191A2 (en) | 2022-06-23 |
| US20220281914A1 (en) | 2022-09-08 |
| WO2022133191A3 (en) | 2022-07-28 |
| EP4263597A2 (en) | 2023-10-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| WO2021231237A3 (en) | Antibodies for sars-cov-2 and uses thereof | |
| AU2018338322A1 (en) | A33 antibody compositions and methods of using the same in radioimmunotherapy | |
| AU2009260320A8 (en) | Antibodies to IL-6 and their uses | |
| MX2009008608A (es) | Anticuerpos monoclonales anti-cxcl13. | |
| WO2021212049A3 (en) | Anti-sars-cov-2 monoclonal antibodies | |
| MX2010001237A (es) | Nuevos anticuerpos. | |
| MX2022001942A (es) | Moléculas de union a antígeno multiespecíficas para el direcciónamiento célular y usos de las mismas. | |
| SA522440646B1 (ar) | أجسام مضادة ترتبط بـ siglec15 واستخداماتها | |
| MX2023004054A (es) | Anticuerpos anti-dectina 1 y metodos de uso de los mismos. | |
| MX2022010665A (es) | Anticuerpos que se unen al receptor de interleucina 4 (il4r) y usos de los mismos. | |
| MX2023010499A (es) | Anticuerpos heterodimericos que se unen a cd3 y cldn6. | |
| MX2022014598A (es) | Anticuerpos anti-glicoproteína espicular sars-cov-2 y fragmentos de unión al antígeno. | |
| MX2023004275A (es) | Anticuerpos biespecificos anti-pd-1/cd40 y usos de los mismos. | |
| MX2023002194A (es) | Moleculas multiespecificas de union a antigenos dirigidas al vih y metodos de uso. | |
| PL439807A1 (pl) | Sposoby oczyszczania przeciwciał i ich kompozycje | |
| MX2022012628A (es) | Anticuerpos anti-phf-tau y usos de estos. | |
| CR20230581A (es) | Anticuerpos anti-CCR8 y usos de los mismos | |
| CO6382184A2 (es) | Proteinas fijadoras de receptores de interleukinas-21 | |
| MX2024000563A (es) | Anticuerpos y fragmentos de union al antigeno anti-glicoproteína de la espícula de sars-cov-2. | |
| MX2024003355A (es) | Anticuerpos anti-cd3. | |
| MX2023013392A (es) | Anticuerpos para tratar alfa-sinucleinopatias. | |
| MX2023011339A (es) | Anticuerpos anti-tau y usos de estos. | |
| CR20230245A (es) | Moléculas de unión a gucy2c y sus usos | |
| ZA202308896B (en) | Antibodies binding trop2 and uses thereof | |
| ATE370163T1 (de) | Antikörper zur isolierung und/oder identifizierung mesenchymaler stammzellen und verfahren zur isolierung und/oder identifizierung mesenchymaler stammzellen |