PT3464361T - Anticorpos anti-cd40 e suas utilizações - Google Patents
Anticorpos anti-cd40 e suas utilizaçõesInfo
- Publication number
- PT3464361T PT3464361T PT177284114T PT17728411T PT3464361T PT 3464361 T PT3464361 T PT 3464361T PT 177284114 T PT177284114 T PT 177284114T PT 17728411 T PT17728411 T PT 17728411T PT 3464361 T PT3464361 T PT 3464361T
- Authority
- PT
- Portugal
- Prior art keywords
- antibodies
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A61K2039/507—Comprising a combination of two or more separate antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/524—CH2 domain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/71—Decreased effector function due to an Fc-modification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/74—Inducing cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/75—Agonist effect on antigen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662342417P | 2016-05-27 | 2016-05-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3464361T true PT3464361T (pt) | 2021-12-27 |
Family
ID=59014833
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT177284114T PT3464361T (pt) | 2016-05-27 | 2017-05-26 | Anticorpos anti-cd40 e suas utilizações |
Country Status (34)
| Country | Link |
|---|---|
| US (8) | US10519243B2 (pt) |
| EP (2) | EP3464361B1 (pt) |
| JP (2) | JP2019523221A (pt) |
| KR (2) | KR102366355B1 (pt) |
| CN (1) | CN109476750B (pt) |
| AR (2) | AR108611A1 (pt) |
| AU (1) | AU2017271602A1 (pt) |
| BR (1) | BR112018074468A2 (pt) |
| CA (1) | CA3025347A1 (pt) |
| CL (1) | CL2018003366A1 (pt) |
| CO (1) | CO2018012699A2 (pt) |
| CR (1) | CR20180605A (pt) |
| CY (1) | CY1124806T1 (pt) |
| DO (1) | DOP2018000258A (pt) |
| EC (1) | ECSP18094829A (pt) |
| ES (1) | ES2901722T3 (pt) |
| HR (1) | HRP20211882T1 (pt) |
| HU (1) | HUE056670T2 (pt) |
| IL (1) | IL263223B2 (pt) |
| LT (1) | LT3464361T (pt) |
| MX (1) | MX2018014630A (pt) |
| MY (1) | MY195442A (pt) |
| NZ (1) | NZ748644A (pt) |
| PE (1) | PE20190970A1 (pt) |
| PH (1) | PH12018502456A1 (pt) |
| PL (1) | PL3464361T3 (pt) |
| PT (1) | PT3464361T (pt) |
| RS (1) | RS62726B1 (pt) |
| RU (1) | RU2752049C2 (pt) |
| SG (2) | SG10201914132RA (pt) |
| SI (1) | SI3464361T1 (pt) |
| TW (2) | TWI814279B (pt) |
| UA (1) | UA123111C2 (pt) |
| WO (1) | WO2017205742A1 (pt) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3097926B1 (en) * | 2007-11-01 | 2019-10-02 | The Board of Trustees of the University of Arkansas | Compositions and methods of enhancing immune responses to eimeria |
| ES2901722T3 (es) | 2016-05-27 | 2022-03-23 | Abbvie Biotherapeutics Inc | Anticuerpos anti-CD40 y sus usos |
| AU2019255781A1 (en) * | 2018-04-20 | 2020-10-29 | Lyvgen Biopharma Holdings Limited | Anti-CD40 antibodies and uses thereof |
| JP2022513624A (ja) | 2018-11-23 | 2022-02-09 | ストライク ファーマ アクティエボラーグ | 二重特異性コンジュゲート |
| WO2020108611A1 (zh) * | 2018-11-30 | 2020-06-04 | 江苏恒瑞医药股份有限公司 | 抗cd40抗体、其抗原结合片段及其医药用途 |
| CN111454362B (zh) * | 2019-03-04 | 2021-03-02 | 北京天广实生物技术股份有限公司 | 特异结合cd40的抗体及其用途 |
| JP2022527506A (ja) | 2019-03-27 | 2022-06-02 | アンセルム（アンスティチュート・ナシオナル・ドゥ・ラ・サンテ・エ・ドゥ・ラ・ルシェルシュ・メディカル） | Ｃｄ４０活性化特性を有する組換えタンパク質 |
| AU2020256828A1 (en) * | 2019-04-10 | 2021-11-18 | Nankai University | Anti-CD40 antibody and use thereof |
| US20220370418A1 (en) | 2019-09-09 | 2022-11-24 | Basilea Pharmaceutica International AG | Pharmaceutical combinations comprising a furazanobenzimidazoles and a cd40 agonist for use in the treatment of neoplastic diseases |
| US20220332836A1 (en) * | 2019-09-11 | 2022-10-20 | Novartis Ag | A method for preventing human virus associated disorders in patients |
| EP4056592A4 (en) * | 2019-11-08 | 2024-03-20 | Jiangsu Simcere Pharm Co Ltd | ANTIBODY AGAINST HUMAN PROGRAMMED CELL DEATH LIGAND 1 (PD-L1) AND USE THEREOF |
| JP2023505168A (ja) * | 2019-12-03 | 2023-02-08 | エヴォテック・インターナショナル・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | インターフェロン会合抗原結合タンパク質及びこれらの使用 |
| GB202008003D0 (en) | 2020-05-28 | 2020-07-15 | Quine Medical Ab | Anti-CD40 antibody |
| US20230346966A1 (en) * | 2020-07-23 | 2023-11-02 | Dyne Therapeutics, Inc. | Muscle-targeting complexes and uses thereof in treating muscle atrophy |
| CN115403670A (zh) * | 2021-05-26 | 2022-11-29 | 安徽瀚海博兴生物技术有限公司 | 抗cd40抗体及其用途 |
| WO2024059899A1 (en) * | 2022-09-20 | 2024-03-28 | Currus Biologics Pty Ltd | Bispecific polypeptides and uses thereof |
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| US4444887A (en) | 1979-12-10 | 1984-04-24 | Sloan-Kettering Institute | Process for making human antibody producing B-lymphocytes |
| US4634665A (en) | 1980-02-25 | 1987-01-06 | The Trustees Of Columbia University In The City Of New York | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US4399216A (en) | 1980-02-25 | 1983-08-16 | The Trustees Of Columbia University | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US5179017A (en) | 1980-02-25 | 1993-01-12 | The Trustees Of Columbia University In The City Of New York | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US4716111A (en) | 1982-08-11 | 1987-12-29 | Trustees Of Boston University | Process for producing human antibodies |
| US4510245A (en) | 1982-11-18 | 1985-04-09 | Chiron Corporation | Adenovirus promoter system |
| GB8308235D0 (en) | 1983-03-25 | 1983-05-05 | Celltech Ltd | Polypeptides |
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| US5807715A (en) | 1984-08-27 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin |
| US5168062A (en) | 1985-01-30 | 1992-12-01 | University Of Iowa Research Foundation | Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence |
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| ES2108048T3 (es) | 1990-08-29 | 1997-12-16 | Genpharm Int | Produccion y utilizacion de animales inferiores transgenicos capaces de producir anticuerpos heterologos. |
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| AR039067A1 (es) | 2001-11-09 | 2005-02-09 | Pfizer Prod Inc | Anticuerpos para cd40 |
| US7217797B2 (en) | 2002-10-15 | 2007-05-15 | Pdl Biopharma, Inc. | Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis |
| PL1707627T3 (pl) * | 2003-12-25 | 2013-04-30 | Kyowa Hakko Kirin Co Ltd | Mutant antagonistycznego przeciwciała anty-CD40 |
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| CN106928362B (zh) | 2011-04-29 | 2021-10-26 | 埃派斯进有限公司 | 抗-cd40抗体及其使用方法 |
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-
2017
- 2017-05-26 ES ES17728411T patent/ES2901722T3/es active Active
- 2017-05-26 SG SG10201914132RA patent/SG10201914132RA/en unknown
- 2017-05-26 RS RS20211552A patent/RS62726B1/sr unknown
- 2017-05-26 AU AU2017271602A patent/AU2017271602A1/en active Pending
- 2017-05-26 NZ NZ748644A patent/NZ748644A/en unknown
- 2017-05-26 PE PE2018003115A patent/PE20190970A1/es unknown
- 2017-05-26 SG SG11201810522UA patent/SG11201810522UA/en unknown
- 2017-05-26 WO PCT/US2017/034681 patent/WO2017205742A1/en active Application Filing
- 2017-05-26 MX MX2018014630A patent/MX2018014630A/es unknown
- 2017-05-26 EP EP17728411.4A patent/EP3464361B1/en active Active
- 2017-05-26 UA UAA201812784A patent/UA123111C2/uk unknown
- 2017-05-26 BR BR112018074468-9A patent/BR112018074468A2/pt unknown
- 2017-05-26 RU RU2018146533A patent/RU2752049C2/ru active
- 2017-05-26 HU HUE17728411A patent/HUE056670T2/hu unknown
- 2017-05-26 HR HRP20211882TT patent/HRP20211882T1/hr unknown
- 2017-05-26 PT PT177284114T patent/PT3464361T/pt unknown
- 2017-05-26 KR KR1020187037322A patent/KR102366355B1/ko active IP Right Grant
- 2017-05-26 CR CR20180605A patent/CR20180605A/es unknown
- 2017-05-26 TW TW111109284A patent/TWI814279B/zh active
- 2017-05-26 TW TW106117521A patent/TWI761348B/zh active
- 2017-05-26 MY MYPI2018002113A patent/MY195442A/en unknown
- 2017-05-26 IL IL263223A patent/IL263223B2/en unknown
- 2017-05-26 LT LTEPPCT/US2017/034681T patent/LT3464361T/lt unknown
- 2017-05-26 SI SI201731001T patent/SI3464361T1/sl unknown
- 2017-05-26 CA CA3025347A patent/CA3025347A1/en active Pending
- 2017-05-26 CN CN201780046023.8A patent/CN109476750B/zh active Active
- 2017-05-26 AR ARP170101447A patent/AR108611A1/es unknown
- 2017-05-26 PL PL17728411T patent/PL3464361T3/pl unknown
- 2017-05-26 JP JP2018561225A patent/JP2019523221A/ja not_active Withdrawn
- 2017-05-26 KR KR1020227005372A patent/KR20220028143A/ko active Application Filing
- 2017-05-26 US US15/606,227 patent/US10519243B2/en active Active
- 2017-05-26 EP EP21200482.4A patent/EP3995511A1/en not_active Withdrawn
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2018
- 2018-02-21 US US15/901,560 patent/US10023645B1/en active Active
- 2018-07-16 US US16/036,691 patent/US10400041B2/en active Active
- 2018-11-22 PH PH12018502456A patent/PH12018502456A1/en unknown
- 2018-11-26 CL CL2018003366A patent/CL2018003366A1/es unknown
- 2018-11-26 CO CONC2018/0012699A patent/CO2018012699A2/es unknown
- 2018-11-26 DO DO2018000258A patent/DOP2018000258A/es unknown
- 2018-12-21 EC ECSENADI201894829A patent/ECSP18094829A/es unknown
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2019
- 2019-09-03 US US16/559,504 patent/US10844131B2/en active Active
- 2019-10-21 US US16/659,209 patent/US10597460B2/en active Active
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2020
- 2020-10-16 US US17/073,150 patent/US20210024642A1/en not_active Abandoned
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2021
- 2021-05-21 US US17/327,264 patent/US20210277137A1/en not_active Abandoned
- 2021-12-03 CY CY20211101058T patent/CY1124806T1/el unknown
- 2021-12-30 US US17/566,149 patent/US20220119542A1/en not_active Abandoned
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2022
- 2022-01-24 AR ARP220100135A patent/AR124692A2/es unknown
- 2022-02-18 JP JP2022023569A patent/JP7331179B2/ja active Active
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