HK1248718A1 - 抗cd40抗體及其用途 - Google Patents

抗cd40抗體及其用途

Info

Publication number
HK1248718A1
HK1248718A1 HK18108161.6A HK18108161A HK1248718A1 HK 1248718 A1 HK1248718 A1 HK 1248718A1 HK 18108161 A HK18108161 A HK 18108161A HK 1248718 A1 HK1248718 A1 HK 1248718A1
Authority
HK
Hong Kong
Prior art keywords
antibodies
Prior art date
Application number
HK18108161.6A
Other languages
English (en)
Inventor
Lorenzo Benatuil
Maria A Argiriadi
Bradford L Mcrae
Chung-Ming Hsieh
Original Assignee
Abbvie Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbvie Inc filed Critical Abbvie Inc
Publication of HK1248718A1 publication Critical patent/HK1248718A1/zh

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
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    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
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    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
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    • C07K2317/567Framework region [FR]
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    • C07ORGANIC CHEMISTRY
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    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/75Agonist effect on antigen
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    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
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HK18108161.6A 2015-05-29 2018-06-26 抗cd40抗體及其用途 HK1248718A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562168425P 2015-05-29 2015-05-29
PCT/US2016/034716 WO2016196314A1 (en) 2015-05-29 2016-05-27 Anti-cd40 antibodies and uses thereof

Publications (1)

Publication Number Publication Date
HK1248718A1 true HK1248718A1 (zh) 2018-10-19

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US (3) US10174121B2 (zh)
EP (3) EP3626744A1 (zh)
JP (3) JP6518917B2 (zh)
KR (2) KR102661078B1 (zh)
CN (2) CN113603782A (zh)
AR (1) AR104809A1 (zh)
AU (2) AU2016270640B2 (zh)
BR (1) BR112017025693A2 (zh)
CA (1) CA2987051A1 (zh)
CL (1) CL2017003007A1 (zh)
CO (1) CO2017012286A2 (zh)
CR (1) CR20170592A (zh)
CY (1) CY1122593T1 (zh)
DK (1) DK3303395T3 (zh)
DO (1) DOP2017000273A (zh)
EC (1) ECSP17085333A (zh)
ES (1) ES2774016T3 (zh)
HK (1) HK1248718A1 (zh)
HR (1) HRP20200262T1 (zh)
HU (1) HUE048284T2 (zh)
IL (1) IL255961B (zh)
LT (1) LT3303395T (zh)
MX (1) MX2017015143A (zh)
PE (1) PE20180193A1 (zh)
PH (1) PH12017502161A1 (zh)
PL (1) PL3303395T3 (zh)
PT (1) PT3303395T (zh)
RS (1) RS59935B1 (zh)
RU (1) RU2715597C2 (zh)
SI (1) SI3303395T1 (zh)
TW (2) TWI740384B (zh)
UA (1) UA125208C2 (zh)
UY (1) UY36692A (zh)
WO (1) WO2016196314A1 (zh)
ZA (1) ZA201707903B (zh)

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CR20170096A (es) 2014-08-12 2017-06-15 Alligator Bioscience Ab Tratamientos conjuntos con anticuerpos anti cd40
KR102661078B1 (ko) * 2015-05-29 2024-05-23 애브비 인코포레이티드 항-cd40 항체 및 그의 용도
WO2017189964A2 (en) 2016-04-29 2017-11-02 Voyager Therapeutics, Inc. Compositions for the treatment of disease
US11326182B2 (en) 2016-04-29 2022-05-10 Voyager Therapeutics, Inc. Compositions for the treatment of disease
US10519243B2 (en) * 2016-05-27 2019-12-31 Abbvie Biotherapeutics Inc. Anti-CD40 antibodies
EP3471754A1 (en) 2016-06-20 2019-04-24 Kymab Limited Anti-pd-l1 antibodies
ES2923143T3 (es) 2017-05-25 2022-09-23 Bristol Myers Squibb Co Anticuerpos monoclonales antagonistas contra CD40 y sus usos
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