DK3303395T3 - Anti-cd40-antistoffer og anvendelser deraf - Google Patents

Anti-cd40-antistoffer og anvendelser deraf Download PDF

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Publication number
DK3303395T3
DK3303395T3 DK16728520.4T DK16728520T DK3303395T3 DK 3303395 T3 DK3303395 T3 DK 3303395T3 DK 16728520 T DK16728520 T DK 16728520T DK 3303395 T3 DK3303395 T3 DK 3303395T3
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antibodies
applications
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DK16728520.4T
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Inventor
Lorenzo Benatuil
Maria A Argiriadi
Bradford L Mcrae
Chung-Ming Hsieh
David A Egan
John E Harlan
Russell A Judge
Rui Wang
Gillian A Kingsbury
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Abbvie Inc
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    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • AHUMAN NECESSITIES
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    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
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    • C07K2317/00Immunoglobulins specific features
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    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
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    • C07ORGANIC CHEMISTRY
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    • C07K2317/00Immunoglobulins specific features
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    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/567Framework region [FR]
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/75Agonist effect on antigen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
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    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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    • C07ORGANIC CHEMISTRY
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    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • GPHYSICS
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    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70578NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30 CD40 or CD95

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  • Biophysics (AREA)
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DK16728520.4T 2015-05-29 2016-05-27 Anti-cd40-antistoffer og anvendelser deraf DK3303395T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562168425P 2015-05-29 2015-05-29
PCT/US2016/034716 WO2016196314A1 (en) 2015-05-29 2016-05-27 Anti-cd40 antibodies and uses thereof

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US (3) US10174121B2 (da)
EP (3) EP3303395B1 (da)
JP (3) JP6518917B2 (da)
KR (1) KR20180010265A (da)
CN (2) CN113603782A (da)
AR (1) AR104809A1 (da)
AU (2) AU2016270640B2 (da)
BR (1) BR112017025693A2 (da)
CA (1) CA2987051A1 (da)
CL (1) CL2017003007A1 (da)
CO (1) CO2017012286A2 (da)
CR (1) CR20170592A (da)
CY (1) CY1122593T1 (da)
DK (1) DK3303395T3 (da)
DO (1) DOP2017000273A (da)
EC (1) ECSP17085333A (da)
ES (1) ES2774016T3 (da)
HK (1) HK1248718A1 (da)
HR (1) HRP20200262T1 (da)
HU (1) HUE048284T2 (da)
IL (1) IL255961B (da)
LT (1) LT3303395T (da)
MX (1) MX2017015143A (da)
PE (1) PE20180193A1 (da)
PH (1) PH12017502161A1 (da)
PL (1) PL3303395T3 (da)
PT (1) PT3303395T (da)
RS (1) RS59935B1 (da)
RU (1) RU2715597C2 (da)
SI (1) SI3303395T1 (da)
TW (2) TWI740384B (da)
UA (1) UA125208C2 (da)
UY (1) UY36692A (da)
WO (1) WO2016196314A1 (da)
ZA (1) ZA201707903B (da)

Families Citing this family (33)

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DK3180087T3 (da) 2014-08-12 2019-05-13 Alligator Bioscience Ab Kombinationsterapier med anti cd40-antistoffer
RU2715597C2 (ru) * 2015-05-29 2020-03-02 Эббви Инк. Антитела к cd40 и способы их применения
US11299751B2 (en) 2016-04-29 2022-04-12 Voyager Therapeutics, Inc. Compositions for the treatment of disease
EP3448874A4 (en) 2016-04-29 2020-04-22 Voyager Therapeutics, Inc. COMPOSITIONS FOR TREATING A DISEASE
SG10201914132RA (en) * 2016-05-27 2020-03-30 Abbvie Biotherapeutics Inc Anti-cd40 antibodies and their uses
CN109475603B (zh) 2016-06-20 2023-06-13 科马布有限公司 抗pd-l1抗体
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US10174121B2 (en) 2019-01-08
PT3303395T (pt) 2020-02-20
US20220289858A1 (en) 2022-09-15
US20160347850A1 (en) 2016-12-01
AR104809A1 (es) 2017-08-16
JP6842488B2 (ja) 2021-03-17
KR20180010265A (ko) 2018-01-30
TWI688574B (zh) 2020-03-21
UY36692A (es) 2016-12-30
US20190359725A1 (en) 2019-11-28
SI3303395T1 (sl) 2020-03-31
CN113603782A (zh) 2021-11-05
CY1122593T1 (el) 2021-01-27
CO2017012286A2 (es) 2018-02-28
RU2017145554A (ru) 2019-07-02
AU2016270640B2 (en) 2022-03-10
CL2017003007A1 (es) 2018-04-27
ZA201707903B (en) 2021-06-30
ES2774016T3 (es) 2020-07-16
CN107810198A (zh) 2018-03-16
PE20180193A1 (es) 2018-01-26
BR112017025693A2 (pt) 2018-08-14
IL255961B (en) 2022-02-01
HK1248718A1 (zh) 2018-10-19
RU2715597C2 (ru) 2020-03-02
RS59935B1 (sr) 2020-03-31
HRP20200262T1 (hr) 2020-05-29
EP4047022A1 (en) 2022-08-24

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