UY36692A - Anticuerpos anti-cd40 y usos de los mismos - Google Patents

Anticuerpos anti-cd40 y usos de los mismos

Info

Publication number
UY36692A
UY36692A UY0001036692A UY36692A UY36692A UY 36692 A UY36692 A UY 36692A UY 0001036692 A UY0001036692 A UY 0001036692A UY 36692 A UY36692 A UY 36692A UY 36692 A UY36692 A UY 36692A
Authority
UY
Uruguay
Prior art keywords
antibodies
activity
same
portions
human
Prior art date
Application number
UY0001036692A
Other languages
English (en)
Inventor
Bradford L Mcrae
Maria A Argiriadi
Chung-Ming Hsieh
Benatuil Lorenzo
Original Assignee
Abbvie Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbvie Inc filed Critical Abbvie Inc
Publication of UY36692A publication Critical patent/UY36692A/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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    • C—CHEMISTRY; METALLURGY
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    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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    • C07K—PEPTIDES
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    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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    • C07K2317/565—Complementarity determining region [CDR]
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Abstract

Anticuerpos anti-CD40 antagonistas y porciones de unión al antígeno de los mismos. Específicamente, la invención se relaciona con anticuerpos anti- CD40 humanizados. En determinadas formas de realización, los anticuerpos de la invención neutralizan la actividad del CD40 humano (hCD40). Los anticuerpos, o porciones de anticuerpo, de la invención son de utilidad para detectar el CD40 y para inhibir la actividad del CD40, por ejemplo, en un sujeto humano que sufre de un trastorno en el cual la actividad del CD40 es perjudicial.
UY0001036692A 2015-05-29 2016-05-27 Anticuerpos anti-cd40 y usos de los mismos UY36692A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201562168425P 2015-05-29 2015-05-29

Publications (1)

Publication Number Publication Date
UY36692A true UY36692A (es) 2016-12-30

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Application Number Title Priority Date Filing Date
UY0001036692A UY36692A (es) 2015-05-29 2016-05-27 Anticuerpos anti-cd40 y usos de los mismos

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US (3) US10174121B2 (es)
EP (3) EP4047022A1 (es)
JP (3) JP6518917B2 (es)
KR (2) KR20240056663A (es)
CN (2) CN113603782A (es)
AR (1) AR104809A1 (es)
AU (2) AU2016270640B2 (es)
BR (1) BR112017025693A2 (es)
CA (1) CA2987051A1 (es)
CL (1) CL2017003007A1 (es)
CO (1) CO2017012286A2 (es)
CR (1) CR20170592A (es)
CY (1) CY1122593T1 (es)
DK (1) DK3303395T3 (es)
DO (1) DOP2017000273A (es)
EC (1) ECSP17085333A (es)
ES (1) ES2774016T3 (es)
HK (1) HK1248718A1 (es)
HR (1) HRP20200262T1 (es)
HU (1) HUE048284T2 (es)
IL (1) IL255961B (es)
LT (1) LT3303395T (es)
MX (1) MX2017015143A (es)
PE (1) PE20180193A1 (es)
PH (1) PH12017502161A1 (es)
PL (1) PL3303395T3 (es)
PT (1) PT3303395T (es)
RS (1) RS59935B1 (es)
RU (1) RU2715597C2 (es)
SI (1) SI3303395T1 (es)
TW (2) TWI688574B (es)
UA (1) UA125208C2 (es)
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