ATE518007T1 - Verfahren und vorrichtung zur korrelierung der ebenen von biomarker-produkten mit erkrankungen - Google Patents
Verfahren und vorrichtung zur korrelierung der ebenen von biomarker-produkten mit erkrankungenInfo
- Publication number
- ATE518007T1 ATE518007T1 AT06836517T AT06836517T ATE518007T1 AT E518007 T1 ATE518007 T1 AT E518007T1 AT 06836517 T AT06836517 T AT 06836517T AT 06836517 T AT06836517 T AT 06836517T AT E518007 T1 ATE518007 T1 AT E518007T1
- Authority
- AT
- Austria
- Prior art keywords
- colorectal
- products
- test individual
- correling
- diseases
- Prior art date
Links
- 239000000090 biomarker Substances 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 230000007170 pathology Effects 0.000 abstract 6
- 238000012360 testing method Methods 0.000 abstract 3
- 206010009944 Colon cancer Diseases 0.000 abstract 1
- 208000001333 Colorectal Neoplasms Diseases 0.000 abstract 1
- 238000012544 monitoring process Methods 0.000 abstract 1
- 238000010998 test method Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/30—Detection of binding sites or motifs
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/50—Mutagenesis
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
- G16B25/10—Gene or protein expression profiling; Expression-ratio estimation or normalisation
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
- G16B40/10—Signal processing, e.g. from mass spectrometry [MS] or from PCR
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
- G16B40/20—Supervised data analysis
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
- G16B40/30—Unsupervised data analysis
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
- G16B5/20—Probabilistic models
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/30—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
- Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medical Informatics (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Evolutionary Biology (AREA)
- Theoretical Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Data Mining & Analysis (AREA)
- Public Health (AREA)
- Databases & Information Systems (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Pathology (AREA)
- Artificial Intelligence (AREA)
- Evolutionary Computation (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Software Systems (AREA)
- Bioethics (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Wood Science & Technology (AREA)
- Physiology (AREA)
- Microbiology (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Probability & Statistics with Applications (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72905505P | 2005-10-21 | 2005-10-21 | |
| US75841806P | 2006-01-12 | 2006-01-12 | |
| PCT/US2006/041600 WO2007048074A1 (en) | 2005-10-21 | 2006-10-23 | Method and apparatus for correlating levels of biomarker products with disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE518007T1 true ATE518007T1 (de) | 2011-08-15 |
Family
ID=37734038
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06836517T ATE518007T1 (de) | 2005-10-21 | 2006-10-23 | Verfahren und vorrichtung zur korrelierung der ebenen von biomarker-produkten mit erkrankungen |
Country Status (9)
| Country | Link |
|---|---|
| US (4) | US8239136B2 (de) |
| EP (2) | EP1945816B1 (de) |
| JP (2) | JP5237817B2 (de) |
| CN (2) | CN101370946B (de) |
| AT (1) | ATE518007T1 (de) |
| AU (2) | AU2006304883A1 (de) |
| CA (1) | CA2626604A1 (de) |
| TW (1) | TW200730825A (de) |
| WO (1) | WO2007048074A1 (de) |
Families Citing this family (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1945816B1 (de) * | 2005-10-21 | 2011-07-27 | GeneNews Inc. | Verfahren und vorrichtung zur korrelierung der ebenen von biomarker-produkten mit erkrankungen |
| JP4661640B2 (ja) * | 2006-03-09 | 2011-03-30 | 株式会社日立製作所 | 空調制御システム |
| EP1849878A1 (de) * | 2006-04-24 | 2007-10-31 | DKFZ Deutsches Krebsforschungszentrum | Mittel und Verfahren zur Diagnose und Behandlung von Krebs, basierend auf dem FRMD3-Gen |
| US7844609B2 (en) | 2007-03-16 | 2010-11-30 | Expanse Networks, Inc. | Attribute combination discovery |
| EP2130028A1 (de) * | 2007-03-29 | 2009-12-09 | Response Biomedical Corporation | Modulares testlesersystem und gerät |
| WO2009037572A2 (en) | 2007-06-04 | 2009-03-26 | Diagnoplex | Biomarker combinations for colorectal cancer |
| EP2215112A1 (de) | 2007-11-26 | 2010-08-11 | Merck Serono S.A. | Neue bank1-spleissvariante |
| US8921074B2 (en) | 2008-04-10 | 2014-12-30 | Genenews, Inc. | Method and apparatus for determining a probability of colorectal cancer in a subject |
| US8108406B2 (en) | 2008-12-30 | 2012-01-31 | Expanse Networks, Inc. | Pangenetic web user behavior prediction system |
| EP2370929A4 (de) | 2008-12-31 | 2016-11-23 | 23Andme Inc | Suche nach verwandten in einer datenbank |
| WO2010100113A1 (en) * | 2009-03-03 | 2010-09-10 | Merck Serono S.A. | Bank1 related snps and sle and/or ms susceptibility |
| WO2011040133A1 (ja) * | 2009-10-02 | 2011-04-07 | 学校法人 東京女子医科大学 | ヒト血清アミロイドa3抗体およびその利用 |
| CA2777417A1 (en) * | 2009-10-21 | 2011-04-28 | Basf Plant Science Company Gmbh | Method for generating biomarker reference patterns |
| US20110161257A1 (en) * | 2009-12-24 | 2011-06-30 | Bell Stephen S | Method, simulator assembly, and storage device for interacting with a regression model |
| EP2348131A1 (de) * | 2010-01-22 | 2011-07-27 | Institut Curie | Niedrige Mengen von Cytidindeaminase als Marker für genetische Prädisposition zur Entwicklung von Krebs |
| WO2011118655A1 (ja) * | 2010-03-23 | 2011-09-29 | オリンパス株式会社 | 幹細胞の分化状態をモニタリングする方法 |
| EP2388336A1 (de) | 2010-05-19 | 2011-11-23 | Signature Diagnostics AG | Verfahren und Kits zur Diagnostizierung eines kolorektalen Karzinoms |
| EP2598874B1 (de) * | 2010-07-28 | 2018-10-24 | Janssen Diagnostics, LLC | Verfahren zur bestimmung des ansprechens auf eine behandlung akuter myeloischer leukämie mit farnesyltransferaseinhibitoren |
| US11559540B2 (en) | 2010-07-28 | 2023-01-24 | Janssen Pharmaceutica Nv | Method of determining acute myeloid leukemia response to treatment with farnesyltransferase inhibitors |
| US9208405B2 (en) | 2010-08-06 | 2015-12-08 | Sony Corporation | Systems and methods for digital image analysis |
| JP6126012B2 (ja) * | 2010-12-17 | 2017-05-10 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | 定量試料分析のための分離および検出処理の複数の装置の自動制御 |
| CN103403543B9 (zh) | 2011-01-25 | 2017-05-17 | 阿尔玛克诊断有限公司 | 结肠癌基因表达签名及使用方法 |
| EP2524968A1 (de) * | 2011-05-19 | 2012-11-21 | Signature Diagnostics AG | Verfahren und Kits zur Diagnostizierung eines kolorektalen Karzinoms |
| EP2524967A1 (de) * | 2011-05-19 | 2012-11-21 | Signature Diagnostics AG | Verfahren und Kits zur Diagnostizierung eines kolorektalen Karzinoms |
| WO2013045464A1 (en) * | 2011-09-26 | 2013-04-04 | Roche Diagnostics Gmbh | Cdna biomarkers in whole blood for colorectal cancer assessment |
| CA2852098C (en) * | 2011-10-21 | 2023-05-02 | Chronix Biomedical | Colorectal cancer associated circulating nucleic acid biomarkers |
| US9476882B2 (en) | 2011-12-29 | 2016-10-25 | The Brigham And Women's Hospital, Inc. | Methods and compositions for diagnosing and treating cancer |
| DE102012209059B4 (de) | 2012-05-30 | 2024-05-02 | Siemens Healthineers Ag | Verfahren und Vorrichtung zur Bestimmung einer zeitlichen Änderung eines Biomarkers in einem Untersuchungsgebiet |
| TWI485252B (zh) * | 2012-09-17 | 2015-05-21 | Cathay General Hospital | 一種以糞便中細胞基因套組偵測大腸直腸癌可能性的方法 |
| CA2892587A1 (en) * | 2012-12-14 | 2014-06-19 | Mindera Corporation | Methods and devices for detection and acquisition of biomarkers |
| WO2014183013A2 (en) * | 2013-05-10 | 2014-11-13 | Luminescent MD, LLC | Guanine chemiluminescence compound and applications |
| AU2015277059B2 (en) | 2014-06-18 | 2021-06-17 | Clear Gene, Inc. | Methods, compositions, and devices for rapid analysis of biological markers |
| JP6270221B2 (ja) * | 2015-02-13 | 2018-01-31 | 国立研究開発法人産業技術総合研究所 | バイオマーカー探索方法、バイオマーカー探索装置、及びプログラム |
| RU2017140779A (ru) * | 2015-04-24 | 2019-05-24 | Дзе Дженерал Хоспитал Корпорейшн | Композиции для лечения рака |
| US10861151B2 (en) * | 2015-08-07 | 2020-12-08 | The Arizona Board Of Regents On Behalf Of Arizona State University | Methods, systems, and media for simultaneously monitoring colonoscopic video quality and detecting polyps in colonoscopy |
| RS60075B1 (sr) | 2015-10-27 | 2020-05-29 | Pharmassist Ltd | Postupak za kvantifikaciju pd-l1 |
| EP3389481A4 (de) | 2015-12-18 | 2019-05-22 | Clear Gene, Inc. | Verfahren, zusammensetzungen, kits und vorrichtungen zur schnellanalyse von biologischen markern |
| EP3181700A1 (de) * | 2015-12-18 | 2017-06-21 | Safeguard Biosystems Holdings Ltd. | Dreidimensionales polymer netzwerk mit darin befindlichen kanälen |
| CN109863503B (zh) | 2016-09-02 | 2023-05-23 | 英维特公司 | 用于单分子定量的系统和方法 |
| US20200190585A1 (en) * | 2017-02-15 | 2020-06-18 | Checkpoint Sciences, Inc. | Data Processing and Classification for Determining a Likelihood Score for Immune-Related Adverse Events |
| US10546237B2 (en) * | 2017-03-30 | 2020-01-28 | Atomwise Inc. | Systems and methods for correcting error in a first classifier by evaluating classifier output in parallel |
| US12275994B2 (en) | 2017-06-22 | 2025-04-15 | Clear Gene, Inc. | Methods and compositions for the analysis of cancer biomarkers |
| CN108300771B (zh) * | 2018-02-13 | 2021-07-20 | 广州海关技术中心 | 一种狐源性成分定量检测的双重数字pcr方法 |
| US20190332947A1 (en) * | 2018-04-30 | 2019-10-31 | International Business Machines Corporation | Estimating errors in predictive models |
| KR20210100115A (ko) | 2018-12-03 | 2021-08-13 | 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 | 올리고-벤즈아미드 유사체 및 암 치료에서의 이의 용도 |
| CN109800790B (zh) * | 2018-12-24 | 2022-08-19 | 厦门大学 | 一种面向高维数据的特征选择方法 |
| JP7652762B2 (ja) * | 2019-08-28 | 2025-03-27 | ベンタナ メディカル システムズ, インコーポレイテッド | 振動分光法によるバイオマーカー発現の無標識評価 |
| CN111261230B (zh) * | 2020-01-17 | 2023-09-15 | 中南大学湘雅三医院 | 基因组合确定方法和装置 |
| CN111489788B (zh) * | 2020-03-27 | 2022-05-20 | 北京航空航天大学 | 解释复杂疾病遗传关系的深度关联核学习系统 |
| WO2022108778A1 (en) * | 2020-11-18 | 2022-05-27 | Kiromic BioPharma, Inc. | Disease-associated isoform identifier |
| US20240229157A1 (en) * | 2021-05-03 | 2024-07-11 | The Regents Of The University Of California | Compositions comprising nullomers and methods of using the same for cancer detection and diagnosis |
| CN113538615B (zh) * | 2021-06-29 | 2024-01-09 | 中国海洋大学 | 基于双流生成器深度卷积对抗生成网络的遥感图像上色方法 |
| CN115948529A (zh) * | 2022-08-01 | 2023-04-11 | 湖南家辉生物技术有限公司 | 一种Cornelia de Lange综合征1型的致病基因、引物对及其应用 |
| CN116243253B (zh) * | 2022-12-15 | 2026-03-24 | 浪潮(山东)计算机科技有限公司 | 一种实现雷达干扰的方法及相关组件 |
| CN118067993B (zh) * | 2024-04-17 | 2024-07-05 | 弗雷米德生物医药技术(天津)有限公司 | 一种用于肠息肉检测的联检试剂盒及其制备方法、检测方法和应用 |
| CN119193863B (zh) * | 2024-11-11 | 2025-07-18 | 武汉轻工大学 | 大白猪初生窝重性状的snp分子标记及其应用 |
Family Cites Families (125)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3654090A (en) | 1968-09-24 | 1972-04-04 | Organon | Method for the determination of antigens and antibodies |
| NL154598B (nl) | 1970-11-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking. |
| US3817837A (en) | 1971-05-14 | 1974-06-18 | Syva Corp | Enzyme amplification assay |
| US3939350A (en) | 1974-04-29 | 1976-02-17 | Board Of Trustees Of The Leland Stanford Junior University | Fluorescent immunoassay employing total reflection for activation |
| US3996345A (en) | 1974-08-12 | 1976-12-07 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| US4016043A (en) | 1975-09-04 | 1977-04-05 | Akzona Incorporated | Enzymatic immunological method for the determination of antigens and antibodies |
| US4196265A (en) | 1977-06-15 | 1980-04-01 | The Wistar Institute | Method of producing antibodies |
| US4277437A (en) | 1978-04-05 | 1981-07-07 | Syva Company | Kit for carrying out chemically induced fluorescence immunoassay |
| US4275149A (en) | 1978-11-24 | 1981-06-23 | Syva Company | Macromolecular environment control in specific receptor assays |
| US4444887A (en) | 1979-12-10 | 1984-04-24 | Sloan-Kettering Institute | Process for making human antibody producing B-lymphocytes |
| US4634665A (en) | 1980-02-25 | 1987-01-06 | The Trustees Of Columbia University In The City Of New York | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US4399216A (en) | 1980-02-25 | 1983-08-16 | The Trustees Of Columbia University | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US5179017A (en) | 1980-02-25 | 1993-01-12 | The Trustees Of Columbia University In The City Of New York | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US4366241A (en) | 1980-08-07 | 1982-12-28 | Syva Company | Concentrating zone method in heterogeneous immunoassays |
| US4411993A (en) | 1981-04-29 | 1983-10-25 | Steven Gillis | Hybridoma antibody which inhibits interleukin 2 activity |
| USRE32011E (en) | 1981-12-14 | 1985-10-22 | Scripps Clinic And Research Foundation | Ultrapurification of factor VIII using monoclonal antibodies |
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| US4716111A (en) | 1982-08-11 | 1987-12-29 | Trustees Of Boston University | Process for producing human antibodies |
| US4543439A (en) | 1982-12-13 | 1985-09-24 | Massachusetts Institute Of Technology | Production and use of monoclonal antibodies to phosphotyrosine-containing proteins |
| GB8308235D0 (en) | 1983-03-25 | 1983-05-05 | Celltech Ltd | Polypeptides |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US5807715A (en) | 1984-08-27 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin |
| US4902614A (en) | 1984-12-03 | 1990-02-20 | Teijin Limited | Monoclonal antibody to human protein C |
| US4980286A (en) | 1985-07-05 | 1990-12-25 | Whitehead Institute For Biomedical Research | In vivo introduction and expression of foreign genetic material in epithelial cells |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| US4902505A (en) | 1986-07-30 | 1990-02-20 | Alkermes | Chimeric peptides for neuropeptide delivery through the blood-brain barrier |
| US5116742A (en) | 1986-12-03 | 1992-05-26 | University Patents, Inc. | RNA ribozyme restriction endoribonucleases and methods |
| US4987071A (en) | 1986-12-03 | 1991-01-22 | University Patents, Inc. | RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods |
| AU622104B2 (en) | 1987-03-11 | 1992-04-02 | Sangtec Molecular Diagnostics Ab | Method of assaying of nucleic acids, a reagent combination and kit therefore |
| US4904582A (en) | 1987-06-11 | 1990-02-27 | Synthetic Genetics | Novel amphiphilic nucleic acid conjugates |
| IL86724A (en) | 1987-06-19 | 1995-01-24 | Siska Diagnostics Inc | Methods and kits for amplification and testing of nucleic acid sequences |
| US5080891A (en) | 1987-08-03 | 1992-01-14 | Ddi Pharmaceuticals, Inc. | Conjugates of superoxide dismutase coupled to high molecular weight polyalkylene glycols |
| AU622426B2 (en) | 1987-12-11 | 1992-04-09 | Abbott Laboratories | Assay using template-dependent nucleic acid probe reorganization |
| AU624601B2 (en) | 1988-01-21 | 1992-06-18 | Genentech Inc. | Amplification and detection of nucleic acid sequences |
| CA1340807C (en) | 1988-02-24 | 1999-11-02 | Lawrence T. Malek | Nucleic acid amplification process |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| EP1997891A1 (de) | 1988-09-02 | 2008-12-03 | Dyax Corporation | Herstellung und Auswahl von Rekombinantproteinen mit verschiedenen Bindestellen |
| US5750373A (en) | 1990-12-03 | 1998-05-12 | Genentech, Inc. | Enrichment method for variant proteins having altered binding properties, M13 phagemids, and growth hormone variants |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US6551784B2 (en) | 1989-06-07 | 2003-04-22 | Affymetrix Inc | Method of comparing nucleic acid sequences |
| US5413923A (en) | 1989-07-25 | 1995-05-09 | Cell Genesys, Inc. | Homologous recombination for universal donor cells and chimeric mammalian hosts |
| US5436146A (en) | 1989-09-07 | 1995-07-25 | The Trustees Of Princeton University | Helper-free stocks of recombinant adeno-associated virus vectors |
| GB8928874D0 (en) | 1989-12-21 | 1990-02-28 | Celltech Ltd | Humanised antibodies |
| US5780225A (en) | 1990-01-12 | 1998-07-14 | Stratagene | Method for generating libaries of antibody genes comprising amplification of diverse antibody DNAs and methods for using these libraries for the production of diverse antigen combining molecules |
| AU7247191A (en) | 1990-01-11 | 1991-08-05 | Molecular Affinities Corporation | Production of antibodies using gene libraries |
| JP3068180B2 (ja) | 1990-01-12 | 2000-07-24 | アブジェニックス インコーポレイテッド | 異種抗体の生成 |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| DE69133476T2 (de) | 1990-08-29 | 2006-01-05 | GenPharm International, Inc., Palo Alto | Transgene Mäuse fähig zur Produktion heterologer Antikörper |
| US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5814318A (en) | 1990-08-29 | 1998-09-29 | Genpharm International Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| US5698426A (en) | 1990-09-28 | 1997-12-16 | Ixsys, Incorporated | Surface expression libraries of heteromeric receptors |
| WO1992006180A1 (en) | 1990-10-01 | 1992-04-16 | University Of Connecticut | Targeting viruses and cells for selective internalization by cells |
| US5455166A (en) | 1991-01-31 | 1995-10-03 | Becton, Dickinson And Company | Strand displacement amplification |
| WO1992018619A1 (en) | 1991-04-10 | 1992-10-29 | The Scripps Research Institute | Heterodimeric receptor libraries using phagemids |
| JPH06510524A (ja) | 1991-05-14 | 1994-11-24 | ユニバーシティ オブ コネチカット | 免疫原性タンパク質をコードする遺伝子の標的への配達 |
| DE69233482T2 (de) | 1991-05-17 | 2006-01-12 | Merck & Co., Inc. | Verfahren zur Verminderung der Immunogenität der variablen Antikörperdomänen |
| AU2160992A (en) | 1991-06-05 | 1993-01-12 | Board Of Regents Acting For And On Behalf Of The University Of Michigan, The | Targeted delivery of genes encoding secretory proteins |
| ES2206447T3 (es) | 1991-06-14 | 2004-05-16 | Genentech, Inc. | Anticuerpo humanizado para heregulina. |
| EP0590067A1 (de) | 1991-06-14 | 1994-04-06 | Xoma Corporation | Mikrobiell hergestellte antikörper-fragmente und deren konjugate |
| US5565332A (en) | 1991-09-23 | 1996-10-15 | Medical Research Council | Production of chimeric antibodies - a combinatorial approach |
| ES2341666T3 (es) | 1991-12-02 | 2010-06-24 | Medimmune Limited | Produccion de autoanticuerpos de repertorios de segmentos de anticue rpos expresados en la superficie de fagos. |
| ES2202310T3 (es) | 1991-12-13 | 2004-04-01 | Xoma Corporation | Metodos y materiales para la preparacion de dominios variables de anticuerpos modificados y sus usos terapeuticos. |
| AU3434393A (en) | 1992-01-17 | 1993-08-03 | Regents Of The University Of Michigan, The | Targeted virus |
| GB9203459D0 (en) | 1992-02-19 | 1992-04-08 | Scotgen Ltd | Antibodies with germ-line variable regions |
| US5733743A (en) | 1992-03-24 | 1998-03-31 | Cambridge Antibody Technology Limited | Methods for producing members of specific binding pairs |
| JPH07505773A (ja) | 1992-04-03 | 1995-06-29 | ヤング アレキサンダー ティー | 標的化されたウイルスベクターを用いた遺伝子治療 |
| US6005079A (en) | 1992-08-21 | 1999-12-21 | Vrije Universiteit Brussels | Immunoglobulins devoid of light chains |
| PT1498427E (pt) | 1992-08-21 | 2010-03-22 | Univ Bruxelles | Imunoglobulinas desprovidas de cadeias leves |
| US5639641A (en) | 1992-09-09 | 1997-06-17 | Immunogen Inc. | Resurfacing of rodent antibodies |
| PT671923E (pt) | 1992-10-09 | 2001-10-30 | Advanced Tissue Sciences Inc | Celulas de reserva do figado |
| DE69333366T2 (de) | 1992-10-30 | 2004-09-16 | The General Hospital Corp., Boston | Ein neues zellzyklus kontrollprotein |
| CA2145641C (en) | 1992-12-03 | 2008-05-27 | Richard J. Gregory | Pseudo-adenovirus vectors |
| US5279721A (en) | 1993-04-22 | 1994-01-18 | Peter Schmid | Apparatus and method for an automated electrophoresis system |
| DE69427974T2 (de) | 1993-04-29 | 2001-12-06 | Unilever N.V., Rotterdam | Herstellung von antikörpern oder funktionstüchtig gemachten teilen davon, abgeleitet von schweren ketten von immunglobulinen von camelidae |
| US6004534A (en) | 1993-07-23 | 1999-12-21 | Massachusetts Institute Of Technology | Targeted polymerized liposomes for improved drug delivery |
| WO1995003035A1 (en) | 1993-07-23 | 1995-02-02 | Massachusetts Institute Of Technology | Polymerized liposomes with enhanced stability for oral delivery |
| WO1995015982A2 (en) | 1993-12-08 | 1995-06-15 | Genzyme Corporation | Process for generating specific antibodies |
| US5827690A (en) | 1993-12-20 | 1998-10-27 | Genzyme Transgenics Corporatiion | Transgenic production of antibodies in milk |
| AU1736495A (en) | 1994-01-31 | 1995-08-15 | Trustees Of Boston University | Polyclonal antibody libraries |
| EP0754240B1 (de) | 1994-02-07 | 2003-08-20 | Beckman Coulter, Inc. | Ligase/polymerase-vermittelte analyse genetischer elemente von einzelnukleotid-polymorphismen und ihre verwendung in der genetischen analyse |
| US5648211A (en) | 1994-04-18 | 1997-07-15 | Becton, Dickinson And Company | Strand displacement amplification using thermophilic enzymes |
| US5516637A (en) | 1994-06-10 | 1996-05-14 | Dade International Inc. | Method involving display of protein binding pairs on the surface of bacterial pili and bacteriophage |
| DE69637481T2 (de) | 1995-04-27 | 2009-04-09 | Amgen Fremont Inc. | Aus immunisierten Xenomäusen stammende menschliche Antikörper gegen IL-8 |
| AU2466895A (en) | 1995-04-28 | 1996-11-18 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| GB9601081D0 (en) | 1995-10-06 | 1996-03-20 | Cambridge Antibody Tech | Specific binding members for human transforming growth factor beta;materials and methods |
| EP0774464B1 (de) | 1995-10-17 | 2004-07-28 | Combichem, Inc. | Matrize für die Synthese kombinatorischer Bibliotheken in Lösung |
| JP2978435B2 (ja) | 1996-01-24 | 1999-11-15 | チッソ株式会社 | アクリロキシプロピルシランの製造方法 |
| DE69739909D1 (de) | 1996-03-26 | 2010-07-29 | Michael S Kopreski | Methoden aus plasma oder serum extrahierte extrazelluraere rna zur diagnoseüberwachung oder evaluation von krebs verwenden |
| US5916771A (en) | 1996-10-11 | 1999-06-29 | Abgenix, Inc. | Production of a multimeric protein by cell fusion method |
| JP4215172B2 (ja) | 1996-12-03 | 2009-01-28 | アムジェン フレモント インク. | 複数のV▲下H▼およびV▲下κ▼領域を含むヒトIg遺伝子座を有するトランスジェニック哺乳動物、ならびにそれから産生される抗体 |
| EP0970126B1 (de) | 1997-04-14 | 2001-04-18 | Micromet AG | Neues verfahren zur herstellung von anti-humanen antigenrezeptoren und deren verwendungen |
| US6235883B1 (en) | 1997-05-05 | 2001-05-22 | Abgenix, Inc. | Human monoclonal antibodies to epidermal growth factor receptor |
| US6190619B1 (en) | 1997-06-11 | 2001-02-20 | Argonaut Technologies, Inc. | Systems and methods for parallel synthesis of compounds |
| WO1999051773A1 (en) | 1998-04-03 | 1999-10-14 | Phylos, Inc. | Addressable protein arrays |
| WO1999052563A1 (en) | 1998-04-16 | 1999-10-21 | The Regents Of The University Of California | A method for the targeting of proteins produced by yersinia into the cytosol of eukaryotic cells |
| US6132969A (en) * | 1998-06-19 | 2000-10-17 | Rosetta Inpharmatics, Inc. | Methods for testing biological network models |
| US6406921B1 (en) | 1998-07-14 | 2002-06-18 | Zyomyx, Incorporated | Protein arrays for high-throughput screening |
| US6221592B1 (en) | 1998-10-20 | 2001-04-24 | Wisconsin Alumi Research Foundation | Computer-based methods and systems for sequencing of individual nucleic acid molecules |
| ATE331811T1 (de) | 1999-04-09 | 2006-07-15 | Exact Sciences Corp | Verfahren zur detektion von nukleinsäuren, welche auf krebs hinweisen |
| US6245527B1 (en) | 1999-06-30 | 2001-06-12 | Millennium Pharmaceuticals, Inc. | Nucleic acid molecules encoding glycoprotein VI and recombinant uses thereof |
| DK1233987T3 (da) | 1999-11-29 | 2009-09-28 | Bac Ip B V | Immobiliserede enkelt-domæne antigenbindende molekyler |
| GB9928787D0 (en) | 1999-12-03 | 2000-02-02 | Medical Res Council | Direct screening method |
| US6602718B1 (en) | 2000-11-08 | 2003-08-05 | Becton, Dickinson And Company | Method and device for collecting and stabilizing a biological sample |
| WO2002044403A2 (en) | 2000-11-29 | 2002-06-06 | Mcgill University | Markers for testing analogs of vitamin d and therapeutical uses |
| US20030190602A1 (en) * | 2001-03-12 | 2003-10-09 | Monogen, Inc. | Cell-based detection and differentiation of disease states |
| US6638722B2 (en) | 2001-06-13 | 2003-10-28 | Invitrogen Corporation | Method for rapid amplification of DNA |
| WO2003040397A2 (en) | 2001-10-25 | 2003-05-15 | Gorilla Genomics, Inc. | Asymmetric pcr with nuclease-free polymerase or nuclease-resistant molecular beacons |
| US20030186303A1 (en) * | 2002-03-29 | 2003-10-02 | Yixin Wang | Colorectal cancer diagnostics |
| US7425618B2 (en) | 2002-06-14 | 2008-09-16 | Medimmune, Inc. | Stabilized anti-respiratory syncytial virus (RSV) antibody formulations |
| WO2004002294A2 (en) * | 2002-06-28 | 2004-01-08 | Hong Kong University Of Science & Technology | Plasma or serum marker and process for detection of cancer |
| WO2004005891A2 (en) * | 2002-07-10 | 2004-01-15 | The Regents Of The University Of Michigan | Expression profile of lung cancer |
| CN1685235A (zh) * | 2002-09-26 | 2005-10-19 | 里格舒斯匹塔里特医院 | 一种用于检测、筛选和/或监控个体内癌症的方法 |
| EP1601969A2 (de) | 2003-03-08 | 2005-12-07 | Auvation Ltd | Marker für dickdarmkrebs |
| US20040265833A1 (en) | 2003-06-23 | 2004-12-30 | Cathy Lofton-Day | Methods and nucleic acids for the analysis of colorectal cell proliferative disorders |
| WO2005024054A1 (en) | 2003-09-05 | 2005-03-17 | Royal Women's Hospital | Diagnostic marker for ovarian cancer |
| WO2005077065A2 (en) | 2004-02-09 | 2005-08-25 | The Regents Of The University Of California | Selective high-affinity polydentate ligands and methods of making such |
| US7575928B2 (en) * | 2004-02-26 | 2009-08-18 | Kaohsiung Medical University | Genes for diagnosing colorectal cancer |
| EP1945816B1 (de) | 2005-10-21 | 2011-07-27 | GeneNews Inc. | Verfahren und vorrichtung zur korrelierung der ebenen von biomarker-produkten mit erkrankungen |
| US8312249B1 (en) | 2008-10-10 | 2012-11-13 | Apple Inc. | Dynamic trampoline and structured code generation in a signed code environment |
| FR2957821B1 (fr) | 2010-03-24 | 2014-08-29 | Inst Francais Du Petrole | Nouvelle zone de regeneration du catalyseur divisee en secteurs pour unites catalytiques regeneratives |
-
2006
- 2006-10-23 EP EP06836517A patent/EP1945816B1/de not_active Not-in-force
- 2006-10-23 CN CN2006800488076A patent/CN101370946B/zh not_active Expired - Fee Related
- 2006-10-23 CA CA002626604A patent/CA2626604A1/en not_active Abandoned
- 2006-10-23 US US11/585,666 patent/US8239136B2/en not_active Expired - Fee Related
- 2006-10-23 US US12/091,049 patent/US8249814B2/en not_active Expired - Fee Related
- 2006-10-23 WO PCT/US2006/041600 patent/WO2007048074A1/en not_active Ceased
- 2006-10-23 CN CN2011101964034A patent/CN102260742A/zh active Pending
- 2006-10-23 JP JP2008536621A patent/JP5237817B2/ja not_active Expired - Fee Related
- 2006-10-23 TW TW095138974A patent/TW200730825A/zh unknown
- 2006-10-23 AU AU2006304883A patent/AU2006304883A1/en not_active Abandoned
- 2006-10-23 AT AT06836517T patent/ATE518007T1/de not_active IP Right Cessation
- 2006-10-23 EP EP11150414A patent/EP2319941A3/de not_active Withdrawn
-
2012
- 2012-08-03 US US13/566,394 patent/US20130013214A1/en not_active Abandoned
-
2013
- 2013-02-25 JP JP2013034252A patent/JP2013150612A/ja not_active Ceased
- 2013-05-16 AU AU2013205891A patent/AU2013205891A1/en not_active Abandoned
-
2015
- 2015-01-14 US US14/597,200 patent/US20150191796A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2013205891A1 (en) | 2013-06-06 |
| US20150191796A1 (en) | 2015-07-09 |
| CN101370946B (zh) | 2011-07-20 |
| EP2319941A3 (de) | 2011-08-17 |
| US20130013214A1 (en) | 2013-01-10 |
| US8249814B2 (en) | 2012-08-21 |
| JP5237817B2 (ja) | 2013-07-17 |
| US20070213939A1 (en) | 2007-09-13 |
| CN101370946A (zh) | 2009-02-18 |
| TW200730825A (en) | 2007-08-16 |
| EP1945816B1 (de) | 2011-07-27 |
| HK1128310A1 (en) | 2009-10-23 |
| WO2007048074B1 (en) | 2007-06-28 |
| JP2009512440A (ja) | 2009-03-26 |
| US8239136B2 (en) | 2012-08-07 |
| AU2006304883A1 (en) | 2007-04-26 |
| US20090208942A1 (en) | 2009-08-20 |
| EP1945816A1 (de) | 2008-07-23 |
| JP2013150612A (ja) | 2013-08-08 |
| WO2007048074A1 (en) | 2007-04-26 |
| CA2626604A1 (en) | 2007-04-26 |
| CN102260742A (zh) | 2011-11-30 |
| EP2319941A2 (de) | 2011-05-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE518007T1 (de) | Verfahren und vorrichtung zur korrelierung der ebenen von biomarker-produkten mit erkrankungen | |
| NO20091389L (no) | Fremgangsmate for benyttelse av malinger av smerteterskel | |
| AR066368A1 (es) | Metodo y aparato para medir el ph de soluciones de baja alcalinidad | |
| EP3953374A4 (de) | Zusammensetzungen und verfahren zur detektion von analyten mittels biolumineszenz | |
| ATE523777T1 (de) | System und verfahren zur bestimmung der analytkonzentration mittels zeitaufgelöster amperometrie | |
| BRPI0603066A (pt) | simulação de procedimento invasivos | |
| BR112015005989A2 (pt) | método, sistema, aparelho e mídia não-transitória legível por computador | |
| NO20080783L (no) | Diagnostisk remsekodingssystem og relaterte anvendelsesmetoder | |
| TW200623232A (en) | Alignment information display method, program thereof, alignment method, exposure method, device manufacturing method, display system, display device, program, and measurement/inspection device | |
| JP2016500110A5 (de) | ||
| ATE520979T1 (de) | Biomarker und verfahren zur bestimmung der empfindlichkeit gegenüber modulatoren des egf(epidermal growth factor)-rezeptors | |
| DE602004012974D1 (de) | Abtastungverfahren und -vorrichtung zur abtastung von korrosion und oberflächenfehlern | |
| EP2883037A4 (de) | Verfahren und vorrichtung zur durchführung und quantifizierung von farbveränderungen durch spezifische konzentrationen von biologischen analyten in einer automatisch kalibrierten umgebung | |
| ATE536553T1 (de) | Verfahren zum nachweis grösserer ungünstiger kardiovaskulärer und zerebrovaskulärer ereignisse | |
| DE602006016397D1 (de) | Analytisches Verfahren und Instrument | |
| ATE541216T1 (de) | Fluoreszenztestverfahren | |
| BR112022011676A2 (pt) | Kit para detectar um analito de interesse em uma pluralidade de amostras líquidas biológicas, método para detectá-lo e /ou quantificá-lo e cartucho para realizar tal método | |
| BR112015018213A8 (pt) | métodos para determinar a síndrome da angústia respiratória aguda (ards) e para monitorar o desenvolvimento desta e kit para diagnóstico". | |
| EA201490946A1 (ru) | Способ количественной оценки лечения рака | |
| WO2008132464A3 (en) | Mek5 and related proteins as biomarkers of neurodegenerative diseases | |
| DE60315715D1 (de) | Verwendung von nicotinamide n-methyltransferase zur diagnose von kolorektalem krebs | |
| ATE550668T1 (de) | Verfahren zur identifizierung von patienten mit erhöhtem risiko für ein unerwünschtes herz- kreislauf-ereignis | |
| BR112012024175A2 (pt) | hbf e a1m como marcadores de estágio precoce para preeclampsia | |
| ATE503846T1 (de) | Verfahren zur diagnose eines ovarialkarzinoms | |
| DE602004025430D1 (de) | Verfahren und Vorrichtungen zur Messung von Kenngrössen von Linsen |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |