SG10202010735PA - Tau-binding antibodies - Google Patents
Tau-binding antibodiesInfo
- Publication number
- SG10202010735PA SG10202010735PA SG10202010735PA SG10202010735PA SG10202010735PA SG 10202010735P A SG10202010735P A SG 10202010735PA SG 10202010735P A SG10202010735P A SG 10202010735PA SG 10202010735P A SG10202010735P A SG 10202010735PA SG 10202010735P A SG10202010735P A SG 10202010735PA
- Authority
- SG
- Singapore
- Prior art keywords
- tau
- binding antibodies
- antibodies
- binding
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/524—CH2 domain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/526—CH3 domain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hospice & Palliative Care (AREA)
- Animal Behavior & Ethology (AREA)
- Psychiatry (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP15175522 | 2015-07-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG10202010735PA true SG10202010735PA (en) | 2020-11-27 |
Family
ID=53524640
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10202010735PA SG10202010735PA (en) | 2015-07-06 | 2016-07-05 | Tau-binding antibodies |
Country Status (28)
Country | Link |
---|---|
US (4) | US10287343B2 (en) |
EP (1) | EP3319983A1 (en) |
JP (3) | JP6630426B2 (en) |
KR (1) | KR20180025962A (en) |
CN (1) | CN107849104B (en) |
AR (1) | AR105267A1 (en) |
AU (1) | AU2016289755C1 (en) |
BR (1) | BR112017028102A2 (en) |
CA (1) | CA2991451A1 (en) |
CL (1) | CL2018000043A1 (en) |
CO (1) | CO2017012971A2 (en) |
EA (1) | EA037092B1 (en) |
EC (1) | ECSP18000887A (en) |
HK (1) | HK1246804A1 (en) |
IL (1) | IL256685B (en) |
MA (2) | MA42377A (en) |
MX (1) | MX2017015817A (en) |
MY (1) | MY193677A (en) |
NZ (1) | NZ738058A (en) |
PE (1) | PE20180481A1 (en) |
PH (1) | PH12017502207A1 (en) |
SG (1) | SG10202010735PA (en) |
TN (1) | TN2017000539A1 (en) |
TW (1) | TWI745295B (en) |
UA (1) | UA124616C2 (en) |
UY (1) | UY36773A (en) |
WO (1) | WO2017005734A1 (en) |
ZA (1) | ZA201800027B (en) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2016270858B2 (en) | 2015-06-05 | 2022-04-28 | Ac Immune Sa | Anti-Tau antibodies and methods of use |
UA124616C2 (en) | 2015-07-06 | 2021-10-20 | Юсб Біофарма Срл | Tau-binding antibodies |
CA2991264C (en) | 2015-07-06 | 2023-10-10 | Ucb Biopharma Sprl | Tau-binding antibodies |
TW202328181A (en) | 2016-12-07 | 2023-07-16 | 美商建南德克公司 | Anti-tau antibodies and methods of use |
KR20240035636A (en) | 2016-12-07 | 2024-03-15 | 제넨테크, 인크. | Anti-tau antibodies and methods of their use |
CN110520440A (en) | 2017-02-17 | 2019-11-29 | 戴纳立制药公司 | Anti- τ antibody and its application method |
JP2018139530A (en) | 2017-02-27 | 2018-09-13 | 帝人ファーマ株式会社 | Humanized antibody for treating or preventing dementia and production method therefor and therapeutic agent or prophylactic agent for dementia using same |
KR102225178B1 (en) | 2017-10-16 | 2021-03-10 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | Anti-tau antibodies and uses thereof |
EP3894438A1 (en) * | 2018-12-13 | 2021-10-20 | INSERM (Institut National de la Santé et de la Recherche Médicale) | New anti tau svqivykpv epitope single domain antibody |
KR20220062287A (en) * | 2019-08-13 | 2022-05-16 | 워싱턴 유니버시티 | MTBR tau isoform detection method and use thereof |
WO2021163031A1 (en) | 2020-02-12 | 2021-08-19 | Eli Lilly And Company | Crystallization of antibodies or antigen-binding fragments |
US11702467B2 (en) | 2020-06-25 | 2023-07-18 | Merck Sharp & Dohme Llc | High affinity antibodies targeting tau phosphorylated at serine 413 |
WO2023092004A1 (en) | 2021-11-17 | 2023-05-25 | Voyager Therapeutics, Inc. | Compositions and methods for the treatment of tau-related disorders |
WO2024107745A1 (en) * | 2022-11-14 | 2024-05-23 | Washington University | Methods to detect csf mtbr-tau and uses thereof |
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GB8422238D0 (en) | 1984-09-03 | 1984-10-10 | Neuberger M S | Chimeric proteins |
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GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
GB8719042D0 (en) | 1987-08-12 | 1987-09-16 | Parker D | Conjugate compounds |
GB8720833D0 (en) | 1987-09-04 | 1987-10-14 | Celltech Ltd | Recombinant dna product |
GB8907617D0 (en) | 1989-04-05 | 1989-05-17 | Celltech Ltd | Drug delivery system |
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AT500379B8 (en) * | 2001-02-02 | 2009-08-15 | Axon Neuroscience | TAU PROTEINS |
US6908963B2 (en) | 2001-10-09 | 2005-06-21 | Nektar Therapeutics Al, Corporation | Thioester polymer derivatives and method of modifying the N-terminus of a polypeptide therewith |
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CA2874083C (en) * | 2014-12-05 | 2024-01-02 | Universite Laval | Tdp-43-binding polypeptides useful for the treatment of neurodegenerative diseases |
UA124616C2 (en) | 2015-07-06 | 2021-10-20 | Юсб Біофарма Срл | Tau-binding antibodies |
CA2991264C (en) | 2015-07-06 | 2023-10-10 | Ucb Biopharma Sprl | Tau-binding antibodies |
-
2016
- 2016-07-05 UA UAA201711739A patent/UA124616C2/en unknown
- 2016-07-05 MY MYPI2018700043A patent/MY193677A/en unknown
- 2016-07-05 MX MX2017015817A patent/MX2017015817A/en unknown
- 2016-07-05 CA CA2991451A patent/CA2991451A1/en active Pending
- 2016-07-05 WO PCT/EP2016/065813 patent/WO2017005734A1/en active Application Filing
- 2016-07-05 MA MA042377A patent/MA42377A/en unknown
- 2016-07-05 EP EP16734676.6A patent/EP3319983A1/en active Pending
- 2016-07-05 PE PE2017002750A patent/PE20180481A1/en unknown
- 2016-07-05 CN CN201680039795.4A patent/CN107849104B/en active Active
- 2016-07-05 BR BR112017028102A patent/BR112017028102A2/en active Search and Examination
- 2016-07-05 SG SG10202010735PA patent/SG10202010735PA/en unknown
- 2016-07-05 JP JP2018500423A patent/JP6630426B2/en active Active
- 2016-07-05 EA EA201890172A patent/EA037092B1/en not_active IP Right Cessation
- 2016-07-05 TN TNP/2017/000539A patent/TN2017000539A1/en unknown
- 2016-07-05 US US15/742,087 patent/US10287343B2/en active Active
- 2016-07-05 KR KR1020187003689A patent/KR20180025962A/en not_active Application Discontinuation
- 2016-07-05 AU AU2016289755A patent/AU2016289755C1/en active Active
- 2016-07-05 NZ NZ738058A patent/NZ738058A/en unknown
- 2016-07-05 MA MA41670A patent/MA41670A1/en unknown
- 2016-07-06 TW TW105121455A patent/TWI745295B/en active
- 2016-07-06 AR ARP160102045A patent/AR105267A1/en unknown
- 2016-07-06 UY UY0001036773A patent/UY36773A/en not_active Application Discontinuation
-
2017
- 2017-12-04 PH PH12017502207A patent/PH12017502207A1/en unknown
- 2017-12-18 CO CONC2017/0012971A patent/CO2017012971A2/en unknown
-
2018
- 2018-01-01 IL IL256685A patent/IL256685B/en unknown
- 2018-01-03 ZA ZA2018/00027A patent/ZA201800027B/en unknown
- 2018-01-05 EC ECIEPI2018887A patent/ECSP18000887A/en unknown
- 2018-01-05 CL CL2018000043A patent/CL2018000043A1/en unknown
- 2018-05-10 HK HK18106080.8A patent/HK1246804A1/en unknown
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2019
- 2019-05-13 US US16/409,945 patent/US10889640B2/en active Active
- 2019-12-06 JP JP2019220807A patent/JP7100008B2/en active Active
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2020
- 2020-12-29 US US17/136,189 patent/US11732034B2/en active Active
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2022
- 2022-06-30 JP JP2022105415A patent/JP7413448B2/en active Active
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2023
- 2023-06-30 US US18/344,945 patent/US20230416350A1/en active Pending
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