|
US6096318A
(en)
|
1973-05-07 |
2000-08-01 |
The Ohio State University |
Antigenically modified HCG polypeptides
|
|
US4902506A
(en)
|
1983-07-05 |
1990-02-20 |
The University Of Rochester |
Immunogenic conjugates
|
|
GB8308235D0
(en)
*
|
1983-03-25 |
1983-05-05 |
Celltech Ltd |
Polypeptides
|
|
US4816567A
(en)
*
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
US5158769A
(en)
*
|
1984-03-07 |
1992-10-27 |
New York Blood Center, Inc. |
Pre-S gene coded peptide hepatitis B immunogens, vaccines, diagnostics, and synthetic lipid vesicle carriers
|
|
US5417986A
(en)
*
|
1984-03-16 |
1995-05-23 |
The United States Of America As Represented By The Secretary Of The Army |
Vaccines against diseases caused by enteropathogenic organisms using antigens encapsulated within biodegradable-biocompatible microspheres
|
|
US5208036A
(en)
*
|
1985-01-07 |
1993-05-04 |
Syntex (U.S.A.) Inc. |
N-(ω, (ω-1)-dialkyloxy)- and N-(ω, (ω-1)-dialkenyloxy)-alk-1-yl-N,N,N-tetrasubstituted ammonium lipids and uses therefor
|
|
US4666829A
(en)
|
1985-05-15 |
1987-05-19 |
University Of California |
Polypeptide marker for Alzheimer's disease and its use for diagnosis
|
|
DE3521994A1
(de)
|
1985-06-20 |
1987-01-02 |
Bayer Ag |
N-(2-aminoacylamido-2-desoxy-hexosyl)-amide-, -carbamate und -harnstoffe, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln
|
|
EP0247091B1
(en)
|
1985-11-01 |
1993-09-29 |
Xoma Corporation |
Modular assembly of antibody genes, antibodies prepared thereby and use
|
|
US5618920A
(en)
*
|
1985-11-01 |
1997-04-08 |
Xoma Corporation |
Modular assembly of antibody genes, antibodies prepared thereby and use
|
|
US4713366A
(en)
|
1985-12-04 |
1987-12-15 |
The Ohio State University Research Foundation |
Antigenic modification of polypeptides
|
|
US5096706A
(en)
*
|
1986-03-25 |
1992-03-17 |
National Research Development Corporation |
Antigen-based treatment for adiposity
|
|
US6548640B1
(en)
*
|
1986-03-27 |
2003-04-15 |
Btg International Limited |
Altered antibodies
|
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
JPS62267297A
(ja)
|
1986-05-15 |
1987-11-19 |
Tokyo Met Gov Seishin Igaku Sogo Kenkyusho |
老人斑反応性モノクロ−ナル抗体、それを産生する細胞株及び該モノクロ−ナル抗体の製造方法
|
|
US5278049A
(en)
*
|
1986-06-03 |
1994-01-11 |
Incyte Pharmaceuticals, Inc. |
Recombinant molecule encoding human protease nexin
|
|
US5231170A
(en)
|
1986-08-27 |
1993-07-27 |
Paul Averback |
Antibodies to dense microspheres
|
|
US5187153A
(en)
*
|
1986-11-17 |
1993-02-16 |
Scios Nova Inc. |
Methods of treatment using Alzheimer's amyloid polypeptide derivatives
|
|
US5223482A
(en)
|
1986-11-17 |
1993-06-29 |
Scios Nova Inc. |
Recombinant Alzheimer's protease inhibitory amyloid protein and method of use
|
|
US5220013A
(en)
|
1986-11-17 |
1993-06-15 |
Scios Nova Inc. |
DNA sequence useful for the detection of Alzheimer's disease
|
|
US4879213A
(en)
|
1986-12-05 |
1989-11-07 |
Scripps Clinic And Research Foundation |
Synthetic polypeptides and antibodies related to Epstein-Barr virus early antigen-diffuse
|
|
DE3702789A1
(de)
|
1987-01-30 |
1988-08-18 |
Bayer Ag |
Vorlaeuferprotein des apc-polypeptids, dafuer codierende dna und diagnostische verwendung der dna und des proteins
|
|
US4912206A
(en)
*
|
1987-02-26 |
1990-03-27 |
The United States Of America As Represented By The Department Of Health And Human Services |
CDNA clone encoding brain amyloid of alzheimer's disease
|
|
EP0307434B2
(en)
|
1987-03-18 |
1998-07-29 |
Scotgen Biopharmaceuticals, Inc. |
Altered antibodies
|
|
JPS63245689A
(ja)
|
1987-03-31 |
1988-10-12 |
Suntory Ltd |
ヒトアミロイド関連蛋白モノクロ−ナル抗体
|
|
US4883666A
(en)
|
1987-04-29 |
1989-11-28 |
Massachusetts Institute Of Technology |
Controlled drug delivery system for treatment of neural disorders
|
|
US5258498A
(en)
|
1987-05-21 |
1993-11-02 |
Creative Biomolecules, Inc. |
Polypeptide linkers for production of biosynthetic proteins
|
|
US5245015A
(en)
|
1991-04-26 |
1993-09-14 |
Tanox Biosystems, Inc. |
Monoclonal antibodies which neutralize HIV-1 through reaction with a conformational epitope in vitro
|
|
US5583112A
(en)
|
1987-05-29 |
1996-12-10 |
Cambridge Biotech Corporation |
Saponin-antigen conjugates and the use thereof
|
|
US5057540A
(en)
|
1987-05-29 |
1991-10-15 |
Cambridge Biotech Corporation |
Saponin adjuvant
|
|
US5641474A
(en)
|
1987-06-24 |
1997-06-24 |
Autoimmune, Inc. |
Prevention of autoimmune diseases by aerosol administration of autoantigens
|
|
US5571500A
(en)
|
1987-06-24 |
1996-11-05 |
Autoimmune, Inc. |
Treatment of autoimmune diseases through administration by inhalation of autoantigens
|
|
EP0359783B2
(en)
|
1987-06-24 |
2002-04-17 |
Autoimmune, Inc. |
Treatment of autoimmune diseases by oral administration of autoantigens
|
|
US5571499A
(en)
|
1987-06-24 |
1996-11-05 |
Autoimmune, Inc. |
Treatment of autoimmune diseases by aerosol administration of autoantigens
|
|
US5849298A
(en)
*
|
1987-06-24 |
1998-12-15 |
Autoimmune Inc. |
Treatment of multiple sclerosis by oral administration of bovine myelin
|
|
US5645820A
(en)
|
1987-06-24 |
1997-07-08 |
Autoimmune, Inc. |
Treatment of autoimmune diseases by aerosol administration of autoantigens
|
|
US5869054A
(en)
*
|
1987-06-24 |
1999-02-09 |
Autoimmune Inc. |
Treatment of multiple sclerosis by oral administration of autoantigens
|
|
US5004697A
(en)
*
|
1987-08-17 |
1991-04-02 |
Univ. Of Ca |
Cationized antibodies for delivery through the blood-brain barrier
|
|
US4966753A
(en)
|
1987-08-18 |
1990-10-30 |
Molecular Rx, Inc. |
Immunotherapeutic methods and compositions employing antigens characteristic of malignant neoplasms
|
|
US5677425A
(en)
|
1987-09-04 |
1997-10-14 |
Celltech Therapeutics Limited |
Recombinant antibody
|
|
US5336603A
(en)
|
1987-10-02 |
1994-08-09 |
Genentech, Inc. |
CD4 adheson variants
|
|
US5231000A
(en)
|
1987-10-08 |
1993-07-27 |
The Mclean Hospital |
Antibodies to A4 amyloid peptide
|
|
CA1339014C
(en)
|
1987-10-08 |
1997-03-25 |
Ronald E. Majocha |
Antibodies to a4 amyloid peptide
|
|
AU2728588A
(en)
|
1987-10-23 |
1989-05-23 |
Genetics Institute Inc. |
Composition and method for treating cancers characterized by over-expression of the c-fms proto-oncogene
|
|
US5089603A
(en)
*
|
1989-06-21 |
1992-02-18 |
Tanox Biosystems, Inc. |
Antigenic epitopes present on membrane-bound but not secreted iga
|
|
WO1989006689A1
(en)
|
1988-01-13 |
1989-07-27 |
The Mclean Hospital Corporation |
Genetic constructs containing the alzheimer brain amyloid gene
|
|
US4912094B1
(en)
|
1988-06-29 |
1994-02-15 |
Ribi Immunochem Research Inc. |
Modified lipopolysaccharides and process of preparation
|
|
US5576184A
(en)
|
1988-09-06 |
1996-11-19 |
Xoma Corporation |
Production of chimeric mouse-human antibodies with specificity to human tumor antigens
|
|
KR900005995A
(ko)
|
1988-10-31 |
1990-05-07 |
우메모또 요시마사 |
변형 인터류킨-2 및 그의 제조방법
|
|
WO1990005142A1
(en)
|
1988-11-10 |
1990-05-17 |
Imperial Cancer Research Technology Ltd. |
Polypeptides
|
|
IL162181A
(en)
|
1988-12-28 |
2006-04-10 |
Pdl Biopharma Inc |
A method of producing humanized immunoglubulin, and polynucleotides encoding the same
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
US5227159A
(en)
|
1989-01-31 |
1993-07-13 |
Miller Richard A |
Anti-idiotype antibodies reactive with shared idiotopes expressed by B cell lymphomas and autoantibodies
|
|
US5262332A
(en)
|
1989-04-05 |
1993-11-16 |
Brigham And Women's Hospital |
Diagnostic method for Alzheimer's disease: examination of non-neural tissue
|
|
AU5525090A
(en)
|
1989-04-14 |
1990-11-16 |
Research Foundation For Mental Hygiene, Inc. |
Monoclonal antibody to amyloid peptide
|
|
WO1990012871A1
(en)
|
1989-04-14 |
1990-11-01 |
Research Foundation For Mental Hygiene, Inc. |
Cerebrovascular amyloid protein-specific monoclonal antibody sv17-6e10
|
|
EP0394827A1
(en)
|
1989-04-26 |
1990-10-31 |
F. Hoffmann-La Roche Ag |
Chimaeric CD4-immunoglobulin polypeptides
|
|
CA2017507C
(en)
|
1989-05-25 |
1996-11-12 |
Gary Van Nest |
Adjuvant formulation comprising a submicron oil droplet emulsion
|
|
JPH0319929A
(ja)
|
1989-06-14 |
1991-01-29 |
Asahi Chem Ind Co Ltd |
オープンエンド紡績の糸
|
|
US5112946A
(en)
|
1989-07-06 |
1992-05-12 |
Repligen Corporation |
Modified pf4 compositions and methods of use
|
|
ES2144398T3
(es)
|
1989-12-20 |
2000-06-16 |
Autoimmune Inc |
Tratamiento mejorado de enfermedades autoinmunes mediante la administracion en aerosol de autoantigenos.
|
|
GB8928874D0
(en)
|
1989-12-21 |
1990-02-28 |
Celltech Ltd |
Humanised antibodies
|
|
US5859205A
(en)
*
|
1989-12-21 |
1999-01-12 |
Celltech Limited |
Humanised antibodies
|
|
EP1690935A3
(en)
|
1990-01-12 |
2008-07-30 |
Abgenix, Inc. |
Generation of xenogeneic antibodies
|
|
AU651097B2
(en)
|
1990-03-02 |
1994-07-14 |
Autoimmune, Inc. |
Enhancement of the down-regulation of autoimmune diseases by oral administration of autoantigens
|
|
EP0451700A1
(en)
|
1990-04-10 |
1991-10-16 |
Miles Inc. |
Recombinant APP minigenes for expression in transgenic mice as models for Alzheimers's disease
|
|
JPH05506990A
(ja)
|
1990-04-24 |
1993-10-14 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
プロテアーゼ ネキシン―２の精製、検出、及び使用方法
|
|
JP2703096B2
(ja)
|
1990-04-26 |
1998-01-26 |
三菱重工業株式会社 |
コンベア付きロボットシステムの教示方法
|
|
JP2980677B2
(ja)
|
1990-04-27 |
1999-11-22 |
マクマイケル，ジョン |
不正常なアミロイドβタンパク質と関連する中枢神経系疾患状態の治療のための方法および組成物
|
|
US5753624A
(en)
|
1990-04-27 |
1998-05-19 |
Milkhaus Laboratory, Inc. |
Materials and methods for treatment of plaquing disease
|
|
GB9009548D0
(en)
|
1990-04-27 |
1990-06-20 |
Celltech Ltd |
Chimeric antibody and method
|
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
|
JPH0415492A
(ja)
|
1990-05-10 |
1992-01-20 |
Mitsubishi Electric Corp |
磁石発電機の冷却ファンおよびその製造方法
|
|
US5349053A
(en)
|
1990-06-01 |
1994-09-20 |
Protein Design Labs, Inc. |
Chimeric ligand/immunoglobulin molecules and their uses
|
|
JPH06507782A
(ja)
*
|
1990-06-15 |
1994-09-08 |
サイオス ノバ インコーポレイテッド |
アルツハイマー病のアミロイド形成開症状を示すヒト以外の組換え哺乳動物
|
|
CA2085897A1
(en)
|
1990-06-19 |
1991-12-20 |
George Pieczenik |
Nonpathogenic variant virus
|
|
GB9014932D0
(en)
|
1990-07-05 |
1990-08-22 |
Celltech Ltd |
Recombinant dna product and method
|
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
|
US5780587A
(en)
|
1990-08-24 |
1998-07-14 |
President And Fellows Of Harvard College |
Compounds and methods for inhibiting β-protein filament formation and neurotoxicity
|
|
US5877397A
(en)
|
1990-08-29 |
1999-03-02 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
|
US5789650A
(en)
|
1990-08-29 |
1998-08-04 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5770429A
(en)
|
1990-08-29 |
1998-06-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5633425A
(en)
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
|
US5625126A
(en)
|
1990-08-29 |
1997-04-29 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5661016A
(en)
|
1990-08-29 |
1997-08-26 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
|
WO1993012227A1
(en)
|
1991-12-17 |
1993-06-24 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
JP2938569B2
(ja)
|
1990-08-29 |
1999-08-23 |
ジェンファーム インターナショナル，インコーポレイティド |
異種免疫グロブリンを作る方法及びトランスジェニックマウス
|
|
US5814318A
(en)
|
1990-08-29 |
1998-09-29 |
Genpharm International Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5874299A
(en)
|
1990-08-29 |
1999-02-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
NZ239643A
(en)
|
1990-09-17 |
1996-05-28 |
North American Vaccine Inc |
Vaccine containing bacterial polysaccharide protein conjugate and adjuvant (c-nd-che-a-co-b-r) with a long chain alkyl group.
|
|
US5702906A
(en)
|
1990-09-25 |
1997-12-30 |
Genentech, Inc. |
Antibodies to neurotrophic factor-4 (NT-4)
|
|
WO1992006187A1
(en)
|
1990-09-28 |
1992-04-16 |
The Upjohn Company |
Transgenic animals with alzheimer's amyloid precursor gene
|
|
EP0553244B8
(en)
|
1990-10-05 |
2005-06-08 |
Celldex Therapeutics, Inc. |
Targeted immunostimulation with bispecific reagents
|
|
AU9023791A
(en)
|
1990-10-15 |
1992-05-20 |
Brigham And Women's Hospital |
Treatment of autoimmune diseases by oral administration of autoantigens
|
|
GB9023352D0
(en)
|
1990-10-26 |
1990-12-05 |
Lynxvale Ltd |
Vaccinia vectors,vaccinia genes and expression products thereof
|
|
WO1992010591A1
(en)
|
1990-12-14 |
1992-06-25 |
Cell Genesys, Inc. |
Chimeric chains for receptor-associated signal transduction pathways
|
|
JP3510244B2
(ja)
|
1991-01-21 |
2004-03-22 |
エラン ファーマシューティカルス，インコーポレイテッド |
アルツハイマー病に関するテストおよびモデル
|
|
ATE194625T1
(de)
|
1991-03-01 |
2000-07-15 |
Merial Sas |
Verfahren zur immunoneutralisierung von nichtkastrierten männlichen haustieren gegen lmrh und peptide dafür
|
|
US5192753A
(en)
*
|
1991-04-23 |
1993-03-09 |
Mcgeer Patrick L |
Anti-rheumatoid arthritic drugs in the treatment of dementia
|
|
DE69229703T2
(de)
|
1991-05-08 |
2000-04-27 |
Schweiz Serum & Impfinst |
Wiederhergestellte Influenza-Virosomen mit immunostimulierenden und immunoverstärkenden Eigenschaften und diese enthaltende Impfstoffe
|
|
WO1994004679A1
(en)
*
|
1991-06-14 |
1994-03-03 |
Genentech, Inc. |
Method for making humanized antibodies
|
|
CA2103059C
(en)
|
1991-06-14 |
2005-03-22 |
Paul J. Carter |
Method for making humanized antibodies
|
|
US5844095A
(en)
|
1991-06-27 |
1998-12-01 |
Bristol-Myers Squibb Company |
CTLA4 Ig fusion proteins
|
|
US5672805A
(en)
|
1991-07-18 |
1997-09-30 |
The Regents Of The University Of California |
Transgenic mice expressing the neurotoxic C-terminus of β-amyloid precursor protein
|
|
JP2966592B2
(ja)
|
1991-07-20 |
1999-10-25 |
萩原 義秀 |
安定化されたヒトモノクローナル抗体製剤
|
|
US5434050A
(en)
|
1991-08-13 |
1995-07-18 |
Regents Of The University Of Minnesota |
Labelled β-amyloid peptide and methods of screening for Alzheimer's disease
|
|
US5837268A
(en)
|
1991-10-16 |
1998-11-17 |
University Of Saskatchewan |
GnRH-leukotoxin chimeras
|
|
ATE243746T1
(de)
|
1992-01-07 |
2003-07-15 |
Elan Pharm Inc |
Transgene tiermodelle fur alzheimer-krankheit
|
|
US5622929A
(en)
|
1992-01-23 |
1997-04-22 |
Bristol-Myers Squibb Company |
Thioether conjugates
|
|
US5679348A
(en)
|
1992-02-03 |
1997-10-21 |
Cedars-Sinai Medical Center |
Immunotherapy for recurrent HSV infections
|
|
EP1958646A1
(en)
|
1992-02-11 |
2008-08-20 |
Henry M. Jackson Foundation For The Advancement Of Military Medicine |
Dual carrier immunogenic construct
|
|
ES2190784T3
(es)
|
1992-02-28 |
2003-08-16 |
Autoimmune Inc |
Supresion de enfermedades autoinmunes por antigenos espectadores.
|
|
US5714350A
(en)
|
1992-03-09 |
1998-02-03 |
Protein Design Labs, Inc. |
Increasing antibody affinity by altering glycosylation in the immunoglobulin variable region
|
|
EP0561087B1
(en)
|
1992-03-20 |
1999-08-04 |
N.V. Innogenetics S.A. |
Mutated form of the beta-amyloid precursor protein gene
|
|
US5447851B1
(en)
|
1992-04-02 |
1999-07-06 |
Univ Texas System Board Of |
Dna encoding a chimeric polypeptide comprising the extracellular domain of tnf receptor fused to igg vectors and host cells
|
|
US5604102A
(en)
*
|
1992-04-15 |
1997-02-18 |
Athena Neurosciences, Inc. |
Methods of screening for β-amyloid peptide production inhibitors
|
|
US5441870A
(en)
*
|
1992-04-15 |
1995-08-15 |
Athena Neurosciences, Inc. |
Methods for monitoring cellular processing of β-amyloid precursor protein
|
|
US5851787A
(en)
*
|
1992-04-20 |
1998-12-22 |
The General Hospital Corporation |
Nucleic acid encoding amyloid precursor-like protein and uses thereof
|
|
CA2118508A1
(en)
|
1992-04-24 |
1993-11-11 |
Elizabeth S. Ward |
Recombinant production of immunoglobulin-like domains in prokaryotic cells
|
|
GB9209118D0
(en)
|
1992-04-28 |
1992-06-10 |
Sb 120 Amsterdam Bv |
Vaccine compositions
|
|
ATE188508T1
(de)
*
|
1992-06-18 |
2000-01-15 |
Harvard College |
Impfstoffe gegen diphtherietoxin
|
|
EP0671948B1
(en)
|
1992-06-25 |
1997-08-13 |
SMITHKLINE BEECHAM BIOLOGICALS s.a. |
Vaccine composition containing adjuvants
|
|
US5766846A
(en)
*
|
1992-07-10 |
1998-06-16 |
Athena Neurosciences |
Methods of screening for compounds which inhibit soluble β-amyloid peptide production
|
|
US6610493B1
(en)
|
1993-06-17 |
2003-08-26 |
Brigham And Women's Hospital |
Screening compounds for the ability to alter the production of amyloid-β peptide
|
|
US5837672A
(en)
|
1992-07-10 |
1998-11-17 |
Athena Neurosciences, Inc. |
Methods and compositions for the detection of soluble β-amyloid peptide
|
|
WO1994001772A1
(en)
|
1992-07-13 |
1994-01-20 |
The Children's Medical Center Corporation |
SCREEN FOR ALZHEIMER'S DISEASE THERAPEUTICS BASED ON β-AMYLOID PRODUCTION
|
|
IL102687A
(en)
|
1992-07-30 |
1997-06-10 |
Yeda Res & Dev |
Conjugates of poorly immunogenic antigens and synthetic pepide carriers and vaccines comprising them
|
|
CA2141427C
(en)
|
1992-07-31 |
2008-07-22 |
Mohammed Anjam Khan |
Expression of recombinant fusion proteins in attenuated bacteria
|
|
DE69333397T2
(de)
|
1992-08-27 |
2004-12-09 |
Bioclones (Proprietary) Ltd., Sandton |
Retro-, inverso-, und retro-inverso synthetische peptidanaloge
|
|
US5958883A
(en)
|
1992-09-23 |
1999-09-28 |
Board Of Regents Of The University Of Washington Office Of Technology |
Animal models of human amyloidoses
|
|
WO1994009364A1
(en)
|
1992-10-13 |
1994-04-28 |
Duke University |
Method of inhibiting binding of amyloid precursor protein to beta-amyloid protein
|
|
ES2346852T3
(es)
|
1992-10-26 |
2010-10-21 |
Elan Pharmaceuticals, Inc. |
Metodos para la identificacion de los compuestos inhibidores de la liberacion del peptido beta-amiloide (betaap).
|
|
US5605811A
(en)
*
|
1992-10-26 |
1997-02-25 |
Athena Neurosciences, Inc. |
Methods and compositions for monitoring cellular processing of beta-amyloid precursor protein
|
|
US5972336A
(en)
|
1992-11-03 |
1999-10-26 |
Oravax Merieux Co. |
Urease-based vaccine against helicobacter infection
|
|
US6210671B1
(en)
*
|
1992-12-01 |
2001-04-03 |
Protein Design Labs, Inc. |
Humanized antibodies reactive with L-selectin
|
|
ES2196024T3
(es)
|
1993-01-22 |
2003-12-16 |
Sloan Kettering Inst Cancer |
Vacunas conjugadas de gangliosido-klh con qs-21.
|
|
US5955317A
(en)
|
1993-01-25 |
1999-09-21 |
Takeda Chemical Industries, Ltd. |
Antibodies to β-amyloids or their derivatives and use thereof
|
|
ATE239797T1
(de)
|
1993-01-25 |
2003-05-15 |
Takeda Chemical Industries Ltd |
Antikörper gegen beta-amyloid oder derivative davon und seine verwendung
|
|
US5358708A
(en)
|
1993-01-29 |
1994-10-25 |
Schering Corporation |
Stabilization of protein formulations
|
|
US5472693A
(en)
|
1993-02-16 |
1995-12-05 |
The Dow Chemical Company |
Family of anti-carcinoembryonic antigen chimeric antibodies
|
|
CA2115811A1
(en)
*
|
1993-02-17 |
1994-08-18 |
Claus Krebber |
A method for in vivo selection of ligand-binding proteins
|
|
CA2115900A1
(en)
|
1993-02-22 |
1994-08-23 |
Gerald W. Becker |
Pharmaceutical screens and antibodies
|
|
DE69435075T2
(de)
*
|
1993-03-17 |
2009-02-19 |
The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services |
Immunogene chimäre umfassend nucleinsäuresequenzen, die signalsequenzpeptide des endoplasmatischen reticulums und mindestens ein anderes peptid codieren, deren verwendung in impfstoffen und zur behandlung von krankheiten
|
|
JP3880063B2
(ja)
|
1993-03-18 |
2007-02-14 |
シティミューン サイエンシーズ，インコーポレイテッド |
生物学的に活性な因子の毒性を低減させる組成物および方法
|
|
ES2109685T5
(es)
|
1993-03-23 |
2005-09-01 |
Smithkline Beecham Biologicals S.A. |
Composiciones para vacunas que contienen monofosforil-lipido a 3-o-desacilado.
|
|
CA2119090A1
(en)
|
1993-03-26 |
1994-09-27 |
Wayne R. Gombotz |
Compositions for controlled release of biologically active tgf-.beta.
|
|
ES2162863T3
(es)
|
1993-04-29 |
2002-01-16 |
Unilever Nv |
Produccion de anticuerpos o fragmentos (funcionalizados) de los mismos derivados de inmunoglobulinas de cadena pesada de camelidae.
|
|
IT1270939B
(it)
|
1993-05-11 |
1997-05-26 |
Angeletti P Ist Richerche Bio |
Procedimento per la preparazione di immunogeni e reagenti diagnostici,e immunogeni e reagenti diagnostici cosi' ottenibili.
|
|
ATE196737T1
(de)
*
|
1993-05-25 |
2000-10-15 |
American Cyanamid Co |
Adjuvantien für impfstoffe gegen das respiratorische synzitialvirus
|
|
WO1994028412A1
(en)
|
1993-05-28 |
1994-12-08 |
The Miriam Hospital |
Composition and method for in vivo imaging of amyloid deposits
|
|
ATE212378T1
(de)
|
1993-06-04 |
2002-02-15 |
Whitehead Biomedical Inst |
Stressproteine und ihre verwendung
|
|
GR1001607B
(el)
|
1993-06-10 |
1994-06-30 |
Lucet Beatrice Yvette Michele |
Πλωτό σύστημα υποστήριξης φραγμάτων με απορροφητικά υλικά για την αντιρρυπαντική προστασία κλειστών ή ημίκλειστων υδάτινων συστημάτων από επιπλέοντες υδρογονάν?ρακες.
|
|
US5464823A
(en)
|
1993-07-20 |
1995-11-07 |
The Regents Of The University Of California |
Mammalian antibiotic peptides
|
|
AU7235794A
(en)
|
1993-07-30 |
1995-02-28 |
Medeva Holdings B.V. |
Vaccine compositions
|
|
WO1995005393A2
(en)
|
1993-08-18 |
1995-02-23 |
Morphosys Gesellschaft Für Proteinoptimierung Mbh |
Lipopolysaccharide-binding and neutralizing peptides
|
|
US6538624B1
(en)
*
|
1993-08-20 |
2003-03-25 |
Seiko Epson Corporation |
Head-mounted image display apparatus
|
|
DK96493D0
(da)
|
1993-08-26 |
1993-08-26 |
Mouritsen Og Elsner Aps |
Fremgangsmaade til at inducere antistofresponser mod selvproteiner og autovaccine fremstillet ved fremgangsmaaden
|
|
CA2169635C
(en)
|
1993-08-26 |
2002-11-12 |
Dennis A. Carson |
Method, compositions and devices for administration of naked polynucleotides which encode biologically active peptides
|
|
WO1995006407A1
(en)
|
1993-08-30 |
1995-03-09 |
The Regents Of The University Of California |
Novel component of amyloid in alzheimer's disease and methods for use of same
|
|
AP583A
(en)
|
1993-09-07 |
1997-04-14 |
Smithkline Beecham Corp |
Recombination IL4 antibodies useful in treatment of IL4 mediated disorders.
|
|
US5652334A
(en)
|
1993-09-08 |
1997-07-29 |
City Of Hope |
Method for design of substances that enhance memory and improve the quality of life
|
|
US5385887A
(en)
*
|
1993-09-10 |
1995-01-31 |
Genetics Institute, Inc. |
Formulations for delivery of osteogenic proteins
|
|
PT735893E
(pt)
*
|
1993-09-14 |
2009-03-06 |
Pharmexa Inc |
Péptidos que se ligam aos alelos pan dr para aumentar a resposta imunitária
|
|
US5470951A
(en)
|
1993-09-29 |
1995-11-28 |
City Of Hope |
Peptides for antagonizing the effects of amyloid βprotein
|
|
US5858981A
(en)
*
|
1993-09-30 |
1999-01-12 |
University Of Pennsylvania |
Method of inhibiting phagocytosis
|
|
EP0728215B1
(en)
|
1993-10-20 |
2002-02-20 |
Duke University |
METHOD OF BINDING MATERIAL TO THE Beta-AMYLOID PEPTIDE
|
|
JP3504963B2
(ja)
|
1993-10-22 |
2004-03-08 |
智靖 羅 |
抗ヒト高親和性ＩｇＥ受容体モノクローナル抗体に係るアミノ酸配列をコードするＤＮＡ断片
|
|
AU7979094A
(en)
|
1993-10-22 |
1995-05-08 |
Genentech Inc. |
Methods and compositions for microencapsulation of adjuvants
|
|
US5744368A
(en)
|
1993-11-04 |
1998-04-28 |
Research Foundation Of State University Of New York |
Methods for the detection of soluble amyloid β-protein (βAP) or soluble transthyretin (TTR)
|
|
JPH07132033A
(ja)
|
1993-11-12 |
1995-05-23 |
Hoechst Japan Ltd |
アルツハイマー病モデルトランスジェニック動物
|
|
US5827690A
(en)
|
1993-12-20 |
1998-10-27 |
Genzyme Transgenics Corporatiion |
Transgenic production of antibodies in milk
|
|
US5434170A
(en)
|
1993-12-23 |
1995-07-18 |
Andrulis Pharmaceuticals Corp. |
Method for treating neurocognitive disorders
|
|
GB9326253D0
(en)
|
1993-12-23 |
1994-02-23 |
Smithkline Beecham Biolog |
Vaccines
|
|
US5877399A
(en)
*
|
1994-01-27 |
1999-03-02 |
Johns Hopkins University |
Transgenic mice expressing APP-Swedish mutation develop progressive neurologic disease
|
|
DE69533583T2
(de)
|
1994-01-27 |
2005-10-06 |
Regents of the University of Minnesota, Southeast, Minneapolis |
Nicht humane, transgenische säugetiere mit sich entwickelnder neurologischer krankheit
|
|
CA2182731A1
(en)
|
1994-02-03 |
1995-08-10 |
Michael P. Vitek |
Compositions and methods for advanced glycosylation endproduct-mediated modulation of amyloidosis
|
|
AUPM411994A0
(en)
|
1994-02-25 |
1994-03-24 |
Deakin Research Limited |
Epitopes
|
|
US5795954A
(en)
|
1994-03-04 |
1998-08-18 |
Genentech, Inc. |
Factor VIIa inhibitors from Kunitz domain proteins
|
|
US6270757B1
(en)
|
1994-04-21 |
2001-08-07 |
Genetics Institute, Inc. |
Formulations for IL-11
|
|
US6372716B1
(en)
|
1994-04-26 |
2002-04-16 |
Genetics Institute, Inc. |
Formulations for factor IX
|
|
AU686818B2
(en)
|
1994-05-25 |
1998-02-12 |
John Mcmichael |
Materials and methods for treatment of plaquing diseases
|
|
US5622701A
(en)
*
|
1994-06-14 |
1997-04-22 |
Protein Design Labs, Inc. |
Cross-reacting monoclonal antibodies specific for E- and P-selectin
|
|
US5798100A
(en)
|
1994-07-06 |
1998-08-25 |
Immunomedics, Inc. |
Multi-stage cascade boosting vaccine
|
|
US6417178B1
(en)
|
1994-07-19 |
2002-07-09 |
University Of Pittsburgh |
Amyloid binding nitrogen-linked compounds for the antemortem diagnosis of alzheimer's disease, in vivo imaging and prevention of amyloid deposits
|
|
NZ290089A
(en)
|
1994-07-27 |
1999-05-28 |
Queensland Inst Med Res |
Recombinant polyepitope cytotoxic t lymphocyte (ctl) vaccines
|
|
GB9415379D0
(en)
|
1994-07-29 |
1994-09-21 |
Smithkline Beecham Plc |
Novel compounds
|
|
EP0784684B8
(en)
|
1994-09-16 |
2008-03-26 |
Cancer Research Institute of Contra Costa |
RECOMBINANT PEPTIDES DERIVED FROM THE Mc3 ANTI-BA46 ANTIBODY, METHODS OF USE THEREOF, AND METHODS OF HUMANIZING ANTIBODY PEPTIDES
|
|
US5872005A
(en)
|
1994-11-03 |
1999-02-16 |
Cell Genesys Inc. |
Packaging cell lines for adeno-associated viral vectors
|
|
US6114133A
(en)
|
1994-11-14 |
2000-09-05 |
Elan Pharmaceuticals, Inc. |
Methods for aiding in the diagnosis of Alzheimer's disease by measuring amyloid-β peptide (x-≧41)
|
|
US5589154A
(en)
|
1994-11-22 |
1996-12-31 |
Rutgers, The State University Of New Jersey |
Methods for the prevention or treatment of vascular hemorrhaging and Alzheimer's disease
|
|
US5688651A
(en)
|
1994-12-16 |
1997-11-18 |
Ramot University Authority For Applied Research And Development Ltd. |
Prevention of protein aggregation
|
|
US5612030A
(en)
|
1995-01-17 |
1997-03-18 |
University Of Kentucky Research Foundation |
Anti-idiotype monoclonal antibody 1A7 and use for the treatment of melanoma and small cell carcinoma
|
|
DE69620877T2
(de)
*
|
1995-02-06 |
2002-12-12 |
Genetics Institute, Inc. |
Arzneimittelformulierungen für il-12
|
|
US5786180A
(en)
|
1995-02-14 |
1998-07-28 |
Bayer Corporation |
Monoclonal antibody 369.2B specific for β A4 peptide
|
|
US5624937A
(en)
*
|
1995-03-02 |
1997-04-29 |
Eli Lilly And Company |
Chemical compounds as inhibitors of amyloid beta protein production
|
|
US5854215A
(en)
|
1995-03-14 |
1998-12-29 |
Praecis Pharmaceuticals Incorporated |
Modulators of β-amyloid peptide aggregation
|
|
CA2214247C
(en)
|
1995-03-14 |
2004-02-10 |
Praecis Pharmaceuticals Incorporated |
Modulators of amyloid aggregation
|
|
US5817626A
(en)
|
1995-03-14 |
1998-10-06 |
Praecis Pharmaceuticals Incorporated |
Modulators of beta-amyloid peptide aggregation
|
|
US6303567B1
(en)
|
1995-03-14 |
2001-10-16 |
Praecis Pharmaceuticals, Inc . |
Modulators of β-amyloid peptide aggregation comprising D-amino acids
|
|
EP0871755A1
(en)
|
1995-03-23 |
1998-10-21 |
Cantab Pharmaceuticals Research Limited |
Vectors for gene delivery
|
|
US6121022A
(en)
|
1995-04-14 |
2000-09-19 |
Genentech, Inc. |
Altered polypeptides with increased half-life
|
|
US5869046A
(en)
*
|
1995-04-14 |
1999-02-09 |
Genentech, Inc. |
Altered polypeptides with increased half-life
|
|
UA56132C2
(uk)
|
1995-04-25 |
2003-05-15 |
Смітклайн Бічем Байолоджікалс С.А. |
Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини
|
|
CA2222055A1
(en)
|
1995-05-23 |
1996-11-28 |
Morphosys Gesellschaft Fur Proteinoptimierung Mbh |
Multimeric proteins
|
|
WO1996039176A1
(en)
|
1995-06-05 |
1996-12-12 |
Brigham & Women's Hospital |
USE OF ORAL TOLERANCE TO SUPPRESS BOTH Th1 AND Th2 IMMUNE RESPONSES AND TO SUPPRESS ANTIBODY PRODUCTION
|
|
CA2221986A1
(en)
|
1995-06-07 |
1996-12-19 |
Athena Neurosciences, Inc. |
Method for identifying alzheimer's disease therapeutics using transgenic animal models
|
|
US5948763A
(en)
|
1995-06-07 |
1999-09-07 |
New York University |
Peptides and pharmaceutical compositions thereof for treatment of disorders or diseases associated with abnormal protein folding into amyloid or amyloid-like deposits
|
|
US5910427A
(en)
|
1995-06-22 |
1999-06-08 |
La Jolla Institute For Allergy And Immunology |
Antigen non-specific glycosylation inhibiting factor derivatives
|
|
PT750907E
(pt)
|
1995-06-30 |
2002-08-30 |
American Cyanamid Co |
Formulacoes de vacinas estaveis para administracao parenterica metodo para a sua utilizacao e processo para a sua preparacao
|
|
JP4073955B2
(ja)
|
1995-07-07 |
2008-04-09 |
ダーウィン モレキュラー コーポレイション |
アルツハイマー病に関連する第１染色体の遺伝子および遺伝子産物
|
|
US6267958B1
(en)
|
1995-07-27 |
2001-07-31 |
Genentech, Inc. |
Protein formulation
|
|
US6685940B2
(en)
|
1995-07-27 |
2004-02-03 |
Genentech, Inc. |
Protein formulation
|
|
AUPN443995A0
(en)
|
1995-07-27 |
1995-08-17 |
Csl Limited |
Papillomavirus polyprotein
|
|
ES2176484T3
(es)
|
1995-08-18 |
2002-12-01 |
Morphosys Ag |
Bancos de proteinas/(poli)peptidos.
|
|
AU6898996A
(en)
|
1995-08-21 |
1997-03-12 |
Cytrx Corporation |
Compositions and methods for growth promotion
|
|
DE852011T1
(de)
|
1995-09-14 |
2001-10-11 |
Scripps Res Inst La Jolla |
Für natives prp-sc spezifische antikörper
|
|
US5731284A
(en)
*
|
1995-09-28 |
1998-03-24 |
Amgen Inc. |
Method for treating Alzheimer's disease using glial line-derived neurotrophic factor (GDNF) protein product
|
|
AU3804995A
(en)
|
1995-10-10 |
1997-04-30 |
Novartis Ag |
Melanoma-associated protein
|
|
US5985242A
(en)
|
1995-10-27 |
1999-11-16 |
Praecis Pharmaceuticals, Inc. |
Modulators of β-amyloid peptide aggregation comprising D-amino acids
|
|
US5750361A
(en)
*
|
1995-11-02 |
1998-05-12 |
The Regents Of The University Of California |
Formation and use of prion protein (PRP) complexes
|
|
CA2234685A1
(en)
|
1995-11-10 |
1997-05-15 |
Elan Corporation, Plc |
Peptides which enhance transport across tissues and methods of identifying and using the same
|
|
WO1997018855A1
(en)
|
1995-11-21 |
1997-05-29 |
Eduard Naumovich Lerner |
Device for enhanced delivery of biologically active substances and compounds in an organism
|
|
AU1072897A
(en)
|
1995-12-12 |
1997-07-03 |
Karolinska Innovations Ab |
Peptide binding the klvff-sequence of amyloid beta
|
|
JPH09178743A
(ja)
|
1995-12-27 |
1997-07-11 |
Oriental Yeast Co Ltd |
可溶性ａｐｐの定量法
|
|
US5723125A
(en)
|
1995-12-28 |
1998-03-03 |
Tanox Biosystems, Inc. |
Hybrid with interferon-alpha and an immunoglobulin Fc linked through a non-immunogenic peptide
|
|
US6015662A
(en)
*
|
1996-01-23 |
2000-01-18 |
Abbott Laboratories |
Reagents for use as calibrators and controls
|
|
US5770700A
(en)
|
1996-01-25 |
1998-06-23 |
Genetics Institute, Inc. |
Liquid factor IX formulations
|
|
ZA97452B
(en)
*
|
1996-01-25 |
1997-08-15 |
Trinity College Dublin |
Streptococcus equi vaccine.
|
|
JPH09208485A
(ja)
|
1996-01-31 |
1997-08-12 |
Teijin Ltd |
ペプチド・蛋白質性薬物の水難溶性組成物
|
|
US6096313A
(en)
|
1996-02-09 |
2000-08-01 |
Ludwig Institute For Cancer Research |
Compositions containing immunogenic molecules and granulocyte-macrophage colony stimulating factor, as an adjuvant
|
|
WO1997032017A1
(en)
|
1996-02-26 |
1997-09-04 |
Morphosys Gesellschaft Für Proteinoptimierung Mbh |
Novel method for the identification of nucleic acid sequences encoding two or more interacting (poly)peptides
|
|
US6150091A
(en)
|
1996-03-06 |
2000-11-21 |
Baylor College Of Medicine |
Direct molecular diagnosis of Friedreich ataxia
|
|
EP0845270B1
(en)
|
1996-03-23 |
2004-10-27 |
The Research Foundation For Microbial Diseases Of Osaka University |
Functional fragment antigen of tetanus toxin and tetanus vaccine
|
|
CN1217751A
(zh)
|
1996-03-29 |
1999-05-26 |
奥塔戈大学 |
副痘病毒载体
|
|
US5837829A
(en)
|
1996-04-02 |
1998-11-17 |
Abbott Laboratories |
9-oximesilyl erythromycin a derivatives
|
|
CA2250814A1
(en)
|
1996-04-03 |
1997-10-09 |
Anergen, Inc. |
Cyclic peptide vaccines for treatment and prevention of diabetes
|
|
EP0904365A1
(en)
|
1996-04-19 |
1999-03-31 |
The Government of the United States Of America, as represented by The Secretary, Department of Health and Human Services |
Antigenically reactive regions of the hepatitis-a virus polyprotein
|
|
US6284533B1
(en)
|
1996-05-01 |
2001-09-04 |
Avant Immunotherapeutics, Inc. |
Plasmid-based vaccine for treating atherosclerosis
|
|
CA2267620A1
(en)
|
1996-07-16 |
1998-01-22 |
Andreas Pluckthun |
Immunoglobulin superfamily domains and fragments with increased solubility
|
|
CA2262006A1
(en)
|
1996-07-26 |
1998-02-05 |
Sloan-Kettering Institute For Cancer Research |
Method and reagents for genetic immunization
|
|
US7147851B1
(en)
|
1996-08-15 |
2006-12-12 |
Millennium Pharmaceuticals, Inc. |
Humanized immunoglobulin reactive with α4β7 integrin
|
|
CA2183901A1
(en)
|
1996-08-22 |
1998-02-23 |
Johanna E. Bergmann |
Targets for therapy and diagnosis of alzheimer's disease and down syndrome in humans
|
|
GB9617616D0
(en)
|
1996-08-22 |
1996-10-02 |
Osteometer Biotech As |
Assaying protein fragments in body fluids
|
|
ATE298765T1
(de)
|
1996-08-27 |
2005-07-15 |
Praecis Pharm Inc |
Beta-amyloid peptidaggregation regulierende peptide mit d-aminosäuren
|
|
US6057367A
(en)
*
|
1996-08-30 |
2000-05-02 |
Duke University |
Manipulating nitrosative stress to kill pathologic microbes, pathologic helminths and pathologically proliferating cells or to upregulate nitrosative stress defenses
|
|
US6797495B2
(en)
|
1996-11-05 |
2004-09-28 |
The Regents Of The University Of California |
Somatic cells with ablated PrP gene and methods of use
|
|
US6022859A
(en)
*
|
1996-11-15 |
2000-02-08 |
Wisconsin Alumni Research Foundation |
Inhibitors of β-amyloid toxicity
|
|
AU5508798A
(en)
|
1996-11-19 |
1998-06-10 |
Trustees Of The University Of Pennsylvania, The |
Diagnostic and therapeutic reagents for alzheimer's disease
|
|
AUPO390396A0
(en)
|
1996-11-29 |
1996-12-19 |
Csl Limited |
Novel promiscuous T helper cell epitopes
|
|
US6962984B2
(en)
|
1996-12-05 |
2005-11-08 |
Nihon University |
IgA nephropathy-related DNA
|
|
US20030068316A1
(en)
|
1997-02-05 |
2003-04-10 |
Klein William L. |
Anti-ADDL antibodies and uses thereof
|
|
US6218506B1
(en)
*
|
1997-02-05 |
2001-04-17 |
Northwestern University |
Amyloid β protein (globular assembly and uses thereof)
|
|
US6277375B1
(en)
|
1997-03-03 |
2001-08-21 |
Board Of Regents, The University Of Texas System |
Immunoglobulin-like domains with increased half-lives
|
|
SK117499A3
(en)
|
1997-03-03 |
2000-05-16 |
Boehringer Ingelheim Pharma |
Small molecules useful in the treatment of inflammatory and immune cell-mediated diseases, small molecules and pharmaceutical composition with their content
|
|
US5798102A
(en)
|
1997-03-04 |
1998-08-25 |
Milkhaus Laboratory, Inc. |
Treatment of cardiomyopathy
|
|
EP2172216A3
(en)
|
1997-03-10 |
2010-11-24 |
Ottawa Hospital Research Institute |
Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant
|
|
US6057098A
(en)
*
|
1997-04-04 |
2000-05-02 |
Biosite Diagnostics, Inc. |
Polyvalent display libraries
|
|
US20020086847A1
(en)
|
1997-04-09 |
2002-07-04 |
Mindset Biopharmaceuticals (Usa) |
Recombinant antibodies specific for beta-amyloid ends, DNA encoding and methods of use thereof
|
|
WO1998044955A1
(en)
|
1997-04-09 |
1998-10-15 |
Mindset Ltd. |
Recombinant antibodies specific for beta-amyloid ends, dna encoding and methods of use thereof
|
|
US8173127B2
(en)
|
1997-04-09 |
2012-05-08 |
Intellect Neurosciences, Inc. |
Specific antibodies to amyloid beta peptide, pharmaceutical compositions and methods of use thereof
|
|
WO1998046642A1
(en)
|
1997-04-15 |
1998-10-22 |
Farmaceutisk Laboratorium Ferring A/S |
MODIFIED TNFα MOLECULES, DNA ENCODING SUCH MODIFIED TNFα MOLECULES AND VACCINES COMPRISING SUCH MODIFIED TNFα MOLECULES AND DNA
|
|
US6787319B2
(en)
|
1997-04-16 |
2004-09-07 |
American Home Products Corp. |
β-amyloid peptide-binding proteins and polynucleotides encoding the same
|
|
ATE370740T1
(de)
*
|
1997-05-20 |
2007-09-15 |
Ottawa Health Research Inst |
Verfahren zur herstellung von nukleinsäurekonstrukten
|
|
EP0999853B1
(en)
|
1997-06-13 |
2003-01-02 |
Genentech, Inc. |
Stabilized antibody formulation
|
|
AU8269898A
(en)
|
1997-06-27 |
1999-01-19 |
Regents Of The University Of California, The |
Drug targeting of a peptide radiopharmaceutical through the primate blood-brain barrier in vivo with a monoclonal antibody to the human insulin receptor
|
|
IT1293511B1
(it)
|
1997-07-30 |
1999-03-01 |
Gentili Ist Spa |
Anticorpi monoclonali catalitici ad attivita' proteasica per la lisi selettiva della componente proteica di placche e aggregati correlati
|
|
IT1293510B1
(it)
|
1997-07-30 |
1999-03-01 |
Gentili Ist Spa |
Anticorpi monoclonali catalitici per la trasformazione in vivo di profarmaci di corticosteroidi
|
|
JP2002501721A
(ja)
|
1997-08-01 |
2002-01-22 |
モルフォシス・アクチェンゲゼルシャフト |
多量体（ポリ）ペプチドコンプレックスのメンバーをコードする核酸配列を同定するための新規方法およびファージ
|
|
DE69842048D1
(de)
|
1997-08-01 |
2011-01-27 |
Max Planck Gesellschaft |
Zusammensetzung und verfahren zum nachweis von krankheiten in zusammenhang mit der bildung von amyloid-ähnlichen fibrillen oder protein-aggregaten
|
|
AU734180B2
(en)
|
1997-08-29 |
2001-06-07 |
Antigenics Llc |
Compositions comprising the adjuvant qs-21 and polysorbate or cyclodextrin as excipient
|
|
US6175057B1
(en)
*
|
1997-10-08 |
2001-01-16 |
The Regents Of The University Of California |
Transgenic mouse model of alzheimer's disease and cerebral amyloid angiopathy
|
|
CA2251263A1
(en)
|
1997-11-14 |
1999-05-14 |
Hajime Karasuyama |
Transgenic animal allergy models and methods for their use
|
|
US6743427B1
(en)
*
|
1997-12-02 |
2004-06-01 |
Neuralab Limited |
Prevention and treatment of amyloidogenic disease
|
|
US7179892B2
(en)
*
|
2000-12-06 |
2007-02-20 |
Neuralab Limited |
Humanized antibodies that recognize beta amyloid peptide
|
|
US6710226B1
(en)
*
|
1997-12-02 |
2004-03-23 |
Neuralab Limited |
Transgenic mouse assay to determine the effect of Aβ antibodies and Aβ Fragments on alzheimer's disease characteristics
|
|
US6750324B1
(en)
|
1997-12-02 |
2004-06-15 |
Neuralab Limited |
Humanized and chimeric N-terminal amyloid beta-antibodies
|
|
US6923964B1
(en)
|
1997-12-02 |
2005-08-02 |
Neuralab Limited |
Active immunization of AScr for prion disorders
|
|
US20080050367A1
(en)
*
|
1998-04-07 |
2008-02-28 |
Guriq Basi |
Humanized antibodies that recognize beta amyloid peptide
|
|
TWI239847B
(en)
*
|
1997-12-02 |
2005-09-21 |
Elan Pharm Inc |
N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease
|
|
US6787523B1
(en)
|
1997-12-02 |
2004-09-07 |
Neuralab Limited |
Prevention and treatment of amyloidogenic disease
|
|
US7790856B2
(en)
|
1998-04-07 |
2010-09-07 |
Janssen Alzheimer Immunotherapy |
Humanized antibodies that recognize beta amyloid peptide
|
|
US7588766B1
(en)
*
|
2000-05-26 |
2009-09-15 |
Elan Pharma International Limited |
Treatment of amyloidogenic disease
|
|
US6913745B1
(en)
*
|
1997-12-02 |
2005-07-05 |
Neuralab Limited |
Passive immunization of Alzheimer's disease
|
|
US7964192B1
(en)
|
1997-12-02 |
2011-06-21 |
Janssen Alzheimer Immunotherapy |
Prevention and treatment of amyloidgenic disease
|
|
US6761888B1
(en)
*
|
2000-05-26 |
2004-07-13 |
Neuralab Limited |
Passive immunization treatment of Alzheimer's disease
|
|
AU742970C
(en)
|
1997-12-03 |
2003-03-20 |
Janssen Alzheimer Immunotherapy |
Method of suppressing beta-amyloid-related changes in Alzheimer's disease
|
|
IL136251A0
(en)
|
1997-12-03 |
2001-05-20 |
Fujisawa Pharmaceutical Co |
Soft pellet drug composition and methods for the preparation thereof
|
|
FR2777015B3
(fr)
|
1998-02-23 |
2000-09-15 |
Financ De Biotechnologie |
Procede et moyens pour l'obtention de modeles cellulaires et animaux de maladies neurodegeneratives
|
|
US6194551B1
(en)
|
1998-04-02 |
2001-02-27 |
Genentech, Inc. |
Polypeptide variants
|
|
US6528624B1
(en)
*
|
1998-04-02 |
2003-03-04 |
Genentech, Inc. |
Polypeptide variants
|
|
US20050059802A1
(en)
|
1998-04-07 |
2005-03-17 |
Neuralab Ltd |
Prevention and treatment of amyloidogenic disease
|
|
US20050059591A1
(en)
*
|
1998-04-07 |
2005-03-17 |
Neuralab Limited |
Prevention and treatment of amyloidogenic disease
|
|
DE69920897T2
(de)
|
1998-04-28 |
2005-10-13 |
Smithkline Beecham Corp. |
Monoklonale antikörper mit verringerter immunisierungsfähigkeit
|
|
NO314086B1
(no)
|
1998-05-08 |
2003-01-27 |
Gemvax As |
Peptider og farmasöytiske sammensetninger inneholdende disse, nukleinsyresekvenser som koder for slike peptider, plasmider og virusvektoreromfattende slike DNA-sekvenser samt anvendelse av disse for fremstilling avfarmasöytiske preparater til
|
|
GB9809951D0
(en)
|
1998-05-08 |
1998-07-08 |
Univ Cambridge Tech |
Binding molecules
|
|
WO1999060021A2
(en)
|
1998-05-19 |
1999-11-25 |
Yeda Research And Development Co. Ltd. |
Use of activated t cells, nervous system-specific antigens for treating disorders of the nevrous system
|
|
WO1999060024A1
(en)
|
1998-05-21 |
1999-11-25 |
The University Of Tennessee Research Corporation |
Methods for amyloid removal using anti-amyloid antibodies
|
|
US20030147882A1
(en)
|
1998-05-21 |
2003-08-07 |
Alan Solomon |
Methods for amyloid removal using anti-amyloid antibodies
|
|
US6432710B1
(en)
|
1998-05-22 |
2002-08-13 |
Isolagen Technologies, Inc. |
Compositions for regenerating tissue that has deteriorated, and methods for using such compositions
|
|
US6727349B1
(en)
*
|
1998-07-23 |
2004-04-27 |
Millennium Pharmaceuticals, Inc. |
Recombinant anti-CCR2 antibodies and methods of use therefor
|
|
PL202399B1
(pl)
|
1998-10-05 |
2009-06-30 |
Pharmexa As |
Zastosowanie adiuwanta i pierwszego analogu polipeptydowego antygenu związanego z komórką lub co najmniej jednego fragmentu kwasu nukleinowego kodującego epitop CTL pochodzący z antygenu polipeptydowego związanego z komórką lub niepatogennego mikroorganizmu lub wirusa, który niesie fragment kwasu nukleinowego, który koduje i wyraża co najmniej jeden epitop CTL pochodzący z antygenu polipeptydowego związanego z komórką, sposób selekcji immunogennego analogu antygenu polipeptydowego związanego z komórką, sposób wytwarzania komórki wytwarzającej analog an
|
|
CA2354862A1
(en)
|
1998-10-19 |
2000-04-27 |
Yeda Research And Development Co. Ltd. |
Treatment of systemic lupus erythematosus by down-regulating the autoimmune response to autoantigens
|
|
US7112661B1
(en)
|
1998-10-30 |
2006-09-26 |
The Research Foundation Of State University Of New York |
Variable heavy chain and variable light chain regions of antibodies to human platelet glycoprotein Ib alpha
|
|
GB2348203B
(en)
|
1998-11-04 |
2002-06-19 |
Imp College Innovations Ltd |
Solube beta-forms of prion proteins, methods of preparation and use
|
|
PT1148891E
(pt)
|
1999-01-19 |
2004-08-31 |
Upjohn Co |
Metodo para embalar uma substancia medicinal sensivel a oxidacao
|
|
CA2361124A1
(en)
|
1999-01-22 |
2000-07-27 |
Matthew John During |
Vaccine-mediated treatment of neurological disorders
|
|
ATE371231T1
(de)
|
1999-02-05 |
2007-09-15 |
Samsung Electronics Co Ltd |
Verfahren und vorrichtung zur wiederauffindung von texturbildern
|
|
US7629311B2
(en)
*
|
1999-02-24 |
2009-12-08 |
Edward Lewis Tobinick |
Methods to facilitate transmission of large molecules across the blood-brain, blood-eye, and blood-nerve barriers
|
|
US20040038317A1
(en)
|
1999-03-15 |
2004-02-26 |
Kalobios, Inc. |
Breakpoint fusion fragment complementation system
|
|
US7282570B2
(en)
*
|
1999-04-20 |
2007-10-16 |
Genentech, Inc. |
Compositions and methods for the treatment of immune related diseases
|
|
IL146009A0
(en)
|
1999-05-05 |
2002-07-25 |
Neurochem Inc |
Stereoselective antifibrillogenic peptides and peptidomimetics thereof
|
|
US6787637B1
(en)
*
|
1999-05-28 |
2004-09-07 |
Neuralab Limited |
N-Terminal amyloid-β antibodies
|
|
UA81216C2
(en)
|
1999-06-01 |
2007-12-25 |
|
Prevention and treatment of amyloid disease
|
|
PE20010212A1
(es)
|
1999-06-01 |
2001-02-22 |
Neuralab Ltd |
Composiciones del peptido a-beta y procesos para producir las mismas
|
|
US7510824B2
(en)
*
|
1999-06-02 |
2009-03-31 |
Nono Inc. |
Method of screening peptides useful in treating traumatic injury to the brain or spinal cord
|
|
ATE405636T1
(de)
|
1999-06-16 |
2008-09-15 |
Boston Biomedical Res Inst |
Immunologische kontrolle des beta-amyloid gehaltes in vivo
|
|
CA2377382A1
(en)
|
1999-07-01 |
2001-01-11 |
Scios, Inc. |
Prevention and treatment of amyloid-associated disorders
|
|
WO2001005355A2
(en)
|
1999-07-15 |
2001-01-25 |
Genetics Institute, Inc. |
Formulations for il-11
|
|
EP1200470B1
(en)
|
1999-08-04 |
2004-11-24 |
The University Of Southern California |
Globular assembly of amyloid beta protein and uses thereof
|
|
CA2349434A1
(en)
|
1999-09-03 |
2001-03-15 |
Ramot University Authority For Applied Research & Industrial Development Ltd. |
Agents and compositions and methods utilizing same useful in diagnosing and/or treating or preventing plaque forming diseases
|
|
US6294171B2
(en)
|
1999-09-14 |
2001-09-25 |
Milkhaus Laboratory, Inc. |
Methods for treating disease states comprising administration of low levels of antibodies
|
|
US6824780B1
(en)
|
1999-10-29 |
2004-11-30 |
Genentech, Inc. |
Anti-tumor antibody compositions and methods of use
|
|
WO2001039796A2
(en)
|
1999-11-29 |
2001-06-07 |
Neurochem Inc. |
Vaccine for the prevention and treatment of alzheimer's and amyloid related diseases
|
|
US20020094335A1
(en)
|
1999-11-29 |
2002-07-18 |
Robert Chalifour |
Vaccine for the prevention and treatment of alzheimer's and amyloid related diseases
|
|
ES2275570T3
(es)
|
1999-12-08 |
2007-06-16 |
Intellect Neurosciences, Inc. |
Peptidos amiloides beta quimericos.
|
|
US6399314B1
(en)
|
1999-12-29 |
2002-06-04 |
American Cyanamid Company |
Methods of detection of amyloidogenic proteins
|
|
AU783144B2
(en)
|
2000-02-21 |
2005-09-29 |
H. Lundbeck A/S |
Novel method for down-regulation of amyloid
|
|
ES2248283T3
(es)
|
2000-02-21 |
2006-03-16 |
Pharmexa A/S |
Nuevo procedimiento para reducir los niveles de amiloide.
|
|
WO2001062801A2
(en)
|
2000-02-24 |
2001-08-30 |
Washington University |
Humanized antibodies that sequester amyloid beta peptide
|
|
EP1353944A2
(en)
|
2000-04-05 |
2003-10-22 |
The University Of Tennessee Research Corporation |
Methods of investigating, diagnosing, and treating amyloidosis
|
|
ATE398463T1
(de)
|
2000-04-13 |
2008-07-15 |
Corixa Corp |
Immunostimulierende zusammnensetzungen die aminoalkyl glucosaminidephosphat und qs-21 enthalten
|
|
ES2238049T3
(es)
|
2000-05-22 |
2005-08-16 |
New York University |
Peptidos sinteticos inmunogenicos pero no amiloidogenicos homologos a los beta amiloides para la induccion de una respuesta inmunitaria a los depositos amiloides y beta-amiloides.
|
|
CA2413354C
(en)
|
2000-06-28 |
2014-04-01 |
Prana Biotechnology Limited |
Neurotoxic a.beta. oligomers in alzheimer's disease
|
|
EP1309341A2
(en)
|
2000-07-07 |
2003-05-14 |
Lars Lannfelt |
Prevention and treatment of alzheimer's disease
|
|
EP1172378A1
(en)
|
2000-07-12 |
2002-01-16 |
Richard Dr. Dodel |
Human beta-amyloid antibody and use thereof for treatment of alzheimer's disease
|
|
US20020009445A1
(en)
*
|
2000-07-12 |
2002-01-24 |
Yansheng Du |
Human beta-amyloid antibody and use thereof for treatment of alzheimer's disease
|
|
DE10038237A1
(de)
|
2000-08-04 |
2002-02-14 |
Aventis Res & Tech Gmbh & Co |
Verfahren zum Nachweis von Mutationen in Nucleotidsequenzen
|
|
US20030092145A1
(en)
|
2000-08-24 |
2003-05-15 |
Vic Jira |
Viral vaccine composition, process, and methods of use
|
|
AU2001290638C1
(en)
|
2000-09-06 |
2009-04-30 |
Aventis Pharma S.A. |
Methods and compositions for diseases associated with amyloidosis
|
|
IT1319277B1
(it)
|
2000-10-24 |
2003-09-26 |
Chiesi Farma Spa |
Proteine di fusione utili per il trattamento di immunizzazione dellamalattia di alzheimer.
|
|
IL139308A0
(en)
|
2000-10-26 |
2001-11-25 |
Marikovsky Moshe |
Peptides from amyloid precursor protein which inhibit tumor growth and metastasis
|
|
WO2002064084A2
(en)
*
|
2000-11-02 |
2002-08-22 |
Cornell Research Foundation, Inc. |
In vivo multiphoton diagnostic detection and imaging of a neurodegenerative disease
|
|
PT1346041E
(pt)
|
2000-11-27 |
2007-06-05 |
Praecis Pharm Inc |
Agentes terapêuticos e métodos para a sua utilização no tratamento de uma doença amiloidogénica.
|
|
US7700751B2
(en)
|
2000-12-06 |
2010-04-20 |
Janssen Alzheimer Immunotherapy |
Humanized antibodies that recognize β-amyloid peptide
|
|
TWI255272B
(en)
*
|
2000-12-06 |
2006-05-21 |
Guriq Basi |
Humanized antibodies that recognize beta amyloid peptide
|
|
WO2002060920A2
(en)
|
2000-12-27 |
2002-08-08 |
Board Of Regents, University Of Texas System |
Prion isomers, methods of making, methods of using, and compositions and products comprising prion isomers
|
|
US20020160394A1
(en)
|
2001-01-24 |
2002-10-31 |
Bayer Corporation |
Regulation of transthyretin to treat obesity
|
|
DE60121729T2
(de)
|
2001-04-19 |
2007-11-29 |
Dr. Hermann Schätzl |
Prion Proteindimere für Impfungen
|
|
US7318923B2
(en)
|
2001-04-30 |
2008-01-15 |
Eli Lilly And Company |
Humanized anti-βantibodies
|
|
AU2002257162A1
(en)
|
2001-04-30 |
2002-11-11 |
Eli Lilly And Company |
Humanized antibodies
|
|
US6906169B2
(en)
*
|
2001-05-25 |
2005-06-14 |
United Biomedical, Inc. |
Immunogenic peptide composition comprising measles virus Fprotein Thelper cell epitope (MUFThl-16) and N-terminus of β-amyloid peptide
|
|
GB0113179D0
(en)
|
2001-05-31 |
2001-07-25 |
Novartis Ag |
Organic compounds
|
|
WO2003000714A2
(en)
|
2001-06-22 |
2003-01-03 |
Panacea Pharmaceuticals, Inc. |
Compositions and methods for preventing protein aggregation in neurodegenerative diseases
|
|
JP4317010B2
(ja)
|
2001-07-25 |
2009-08-19 |
ピーディーエル バイオファーマ，インコーポレイティド |
ＩｇＧ抗体の安定な凍結乾燥医薬製剤
|
|
US20030135035A1
(en)
|
2001-08-09 |
2003-07-17 |
Mark Shannon |
Human ZZAP1 protein
|
|
CA2452104A1
(en)
|
2001-08-17 |
2003-02-27 |
Eli Lilly And Company |
Use of antibodies having high affinity for soluble ass to treat conditions and diseases related to ass
|
|
WO2003015691A2
(en)
|
2001-08-17 |
2003-02-27 |
Eli Lilly And Company |
RAPID IMPROVEMENT OF COGNITION IN CONDITIONS RELATED TO A$g(b)
|
|
EP1432444A4
(en)
|
2001-08-17 |
2005-11-02 |
Lilly Co Eli |
ANTI-BETA ANTIBODIES
|
|
US20030082191A1
(en)
|
2001-08-29 |
2003-05-01 |
Poduslo Joseph F. |
Treatment for central nervous system disorders
|
|
JP4411068B2
(ja)
*
|
2001-09-10 |
2010-02-10 |
アンチキャンサー インコーポレーテッド |
腫瘍転移の解像度の向上
|
|
US6907297B2
(en)
|
2001-09-28 |
2005-06-14 |
Ethicon, Inc. |
Expandable intracardiac return electrode and method of use
|
|
US7781413B2
(en)
|
2001-10-31 |
2010-08-24 |
Board Of Regents, The University Of Texas System |
SEMA3B inhibits tumor growth and induces apoptosis in cancer cells
|
|
ATE556591T1
(de)
|
2001-11-08 |
2012-05-15 |
Abbott Biotherapeutics Corp |
Stabile pharmazeutische flüssigformulierung von igg-antikörpern
|
|
US7479482B2
(en)
|
2001-11-21 |
2009-01-20 |
New York University |
Synthetic immunogenic but non-deposit-forming polypeptides and peptides homologous to amyloid β, prion protein, amylin, α-synuclein, or polyglutamine repeats for induction of an immune response thereto
|
|
WO2003051374A2
(en)
|
2001-12-17 |
2003-06-26 |
New York State Office Of Mental Health |
SEQUESTRATION OF Aβ IN THE PERIPHERY IN THE ABSENCE OF IMMUNOMODULATING AGENT AS A THERAPEUTIC APPROACH FOR THE TREATMENT OR PREVENTION OF BETA-AMYLOID RELATED DISEASES
|
|
US7432063B2
(en)
|
2002-02-14 |
2008-10-07 |
Kalobios Pharmaceuticals, Inc. |
Methods for affinity maturation
|
|
US7335478B2
(en)
|
2002-04-18 |
2008-02-26 |
Kalobios Pharmaceuticals, Inc. |
Reactivation-based molecular interaction sensors
|
|
US20030157579A1
(en)
|
2002-02-14 |
2003-08-21 |
Kalobios, Inc. |
Molecular sensors activated by disinhibition
|
|
AR038568A1
(es)
|
2002-02-20 |
2005-01-19 |
Hoffmann La Roche |
Anticuerpos anti-a beta y su uso
|
|
JP2005526501A
(ja)
|
2002-02-21 |
2005-09-08 |
デューク・ユニヴァーシティ |
自己免疫疾患用の試薬および治療方法
|
|
MY139983A
(en)
|
2002-03-12 |
2009-11-30 |
Janssen Alzheimer Immunotherap |
Humanized antibodies that recognize beta amyloid peptide
|
|
US20040038304A1
(en)
|
2002-03-28 |
2004-02-26 |
Gala Design, Inc. |
Antibody libraries
|
|
US7132100B2
(en)
|
2002-06-14 |
2006-11-07 |
Medimmune, Inc. |
Stabilized liquid anti-RSV antibody formulations
|
|
DK1524994T3
(da)
|
2002-07-19 |
2011-08-15 |
Cytos Biotechnology Ag |
Vaccinesammensætninger indeholdende amyloid beta 1-6-antigen-arrays
|
|
AU2003250102B2
(en)
|
2002-07-24 |
2009-09-17 |
Innogenetics N.V. |
Fragments of beta-amyloid as targets for vaccination against alzheimer disease
|
|
US6827524B2
(en)
*
|
2002-07-26 |
2004-12-07 |
Ingersoll-Rand Company |
Controller for a compacting vehicle wetting system
|
|
AU2003266967B2
(en)
*
|
2002-08-07 |
2006-11-16 |
Novartis Ag |
Methods for the treatment of dementia based on Apo E genotype
|
|
US6802134B2
(en)
|
2002-08-09 |
2004-10-12 |
Patrick J. Allen |
Tapered sliding dovetail tool and kit including such tool
|
|
WO2004029629A1
(en)
|
2002-09-27 |
2004-04-08 |
Janssen Pharmaceutica N.V. |
N-11 truncated amyloid-beta nomoclonal antibodies, compositions, methods and uses
|
|
CA2501091A1
(en)
|
2002-10-01 |
2004-04-15 |
Northwestern University |
Amyloid beta-derived diffusible ligands (addls), addl-surrogates, addl-binding molecules, and uses thereof
|
|
CA2501945A1
(en)
|
2002-10-09 |
2004-04-22 |
Rinat Neuroscience Corp. |
Methods of treating alzheimer's disease using antibodies directed against amyloid beta peptide and compositions thereof
|
|
US7365168B2
(en)
|
2002-10-15 |
2008-04-29 |
Pdl Biopharma, Inc. |
Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
|
|
US20060019850A1
(en)
*
|
2002-10-31 |
2006-01-26 |
Korzenski Michael B |
Removal of particle contamination on a patterned silicon/silicon dioxide using dense fluid/chemical formulations
|
|
FR2846667B1
(fr)
|
2002-11-06 |
2004-12-31 |
Pasteur Institut |
Fragments variables d'anticorps de camelides a chaine unique diriges contre le peptide beta-amyloide 1-42 et leurs applications pour le diagnostic et le traitement des maladies neuroagregatives
|
|
US20040191243A1
(en)
|
2002-12-13 |
2004-09-30 |
Bei Chen |
System and method for stabilizing antibodies with histidine
|
|
US6787129B1
(en)
|
2003-01-13 |
2004-09-07 |
Zenitech Llc |
Castor polyester as gloss agents in anionic systems
|
|
MXPA05008156A
(es)
|
2003-02-01 |
2005-09-30 |
Neuralab Ltd |
Inmunizacion activa para generar anticuerpos para beta-a soluble.
|
|
WO2004071408A2
(en)
|
2003-02-10 |
2004-08-26 |
Applied Molecular Evolution, Inc. |
Aβ BINDING MOLECULES
|
|
US20050008625A1
(en)
|
2003-02-13 |
2005-01-13 |
Kalobios, Inc. |
Antibody affinity engineering by serial epitope-guided complementarity replacement
|
|
US20040242845A1
(en)
|
2003-02-21 |
2004-12-02 |
Nicolau Yves Claude |
Methods and compositions comprising supramolecular antigenic constructs and antibodies elicited against them
|
|
US8663650B2
(en)
|
2003-02-21 |
2014-03-04 |
Ac Immune Sa |
Methods and compositions comprising supramolecular constructs
|
|
KR20060054174A
(ko)
|
2003-03-28 |
2006-05-22 |
센토코 인코포레이티드 |
항-아밀로이드 항체, 조성물, 방법 및 용도
|
|
HRP20050934B1
(hr)
|
2003-04-04 |
2014-09-26 |
Genentech, Inc. |
Formulacije s visokom koncentracijom antitijela i proteina
|
|
EP1480041A1
(en)
|
2003-05-22 |
2004-11-24 |
Innogenetics N.V. |
Method for the prediction, diagnosis and differential diagnosis of Alzheimer's disease
|
|
WO2004106375A1
(en)
|
2003-05-30 |
2004-12-09 |
Merus Biopharmaceuticals B.V. I.O. |
Fab library for the preparation of anti vegf and anti rabies virus fabs
|
|
TWI306458B
(en)
|
2003-05-30 |
2009-02-21 |
Elan Pharma Int Ltd |
Humanized antibodies that recognize beta amyloid peptide
|
|
WO2005002444A1
(en)
|
2003-07-07 |
2005-01-13 |
Agency For Science, Technology And Research |
Method and apparatus for extracting third ventricle information
|
|
WO2005014041A2
(en)
|
2003-07-24 |
2005-02-17 |
Novartis Ag |
Use of an amyloid beta dna vaccine for the treatment and/or prevention of amyloid diseases
|
|
US20050123553A1
(en)
|
2003-07-30 |
2005-06-09 |
Alon Monsonego |
Amyloid beta-peptide and methods of use
|
|
US20060233788A1
(en)
|
2003-09-05 |
2006-10-19 |
Heiman Mark L |
Anti-ghrelin antibodies
|
|
CA2445743A1
(en)
|
2003-10-08 |
2005-04-08 |
The University Of British Columbia |
Methods for modulating neuronal responses
|
|
AU2003271174A1
(en)
|
2003-10-10 |
2005-04-27 |
Chugai Seiyaku Kabushiki Kaisha |
Double specific antibodies substituting for functional protein
|
|
AR046960A1
(es)
|
2003-12-17 |
2006-01-04 |
Wyeth Corp |
Metodos para producir los conjugados portadores de peptidos inmunogenicos
|
|
KR101201120B1
(ko)
|
2003-12-17 |
2012-12-03 |
와이어쓰 엘엘씨 |
Ａβ 면역원성 펩티드 캐리어 컨쥬게이트 및 이의 제조 방법
|
|
EP1702071B1
(en)
|
2003-12-31 |
2012-02-22 |
Kalobios Inc. |
Transactivation system for mammalian cells
|
|
AU2005207003C1
(en)
|
2004-01-20 |
2013-06-13 |
Humanigen, Inc. |
Antibody specificity transfer using minimal essential binding determinants
|
|
US20050214222A1
(en)
|
2004-02-13 |
2005-09-29 |
Mckinnon Stuart J |
In vivo imaging of amyloid plaques in glaucoma using intravenous injectable dyes
|
|
JP4824547B2
(ja)
|
2004-02-20 |
2011-11-30 |
インテレクト ニュウロサイエンシス，インク． |
モノクローナル抗体およびその利用
|
|
UA86053C2
(ru)
|
2004-03-15 |
2009-03-25 |
Янссен Фармацевтика Н.В. |
Соединения как модуляторы опиоидных рецепторов
|
|
FR2871633A1
(fr)
|
2004-06-10 |
2005-12-16 |
France Telecom |
Procede de reduction du bruit de phase lors de la reception d'un signal ofdm, recepteur, programme et support
|
|
SE0401601D0
(sv)
|
2004-06-21 |
2004-06-21 |
Bioarctic Neuroscience Ab |
Protofibril specific antibodies and uses thereof
|
|
CN101137397A
(zh)
|
2004-07-02 |
2008-03-05 |
匹兹堡大学高等教育联邦体系 |
淀粉样蛋白成像作为抗淀粉样蛋白疗法的功效的替代标记物
|
|
AT413946B
(de)
|
2004-07-13 |
2006-07-15 |
Mattner Frank Dr |
Impfstoff gegen die alzheimer-krankheit
|
|
JPWO2006006604A1
(ja)
|
2004-07-13 |
2008-04-24 |
株式会社フジクラ |
孔アシスト型ホーリーファイバおよび低曲げ損失マルチモードホーリーファイバ
|
|
CA2575663C
(en)
*
|
2004-07-30 |
2013-04-23 |
Rinat Neuroscience Corp. |
Antibodies directed against amyloid-beta peptide and methods using same
|
|
RU2007108716A
(ru)
*
|
2004-09-10 |
2008-10-20 |
Вайет (Us) |
Гуманизированные антитела к антигену 5т4 и конъюгаты гуманизированного антитела к антигену 5т4 с калихеамицином
|
|
CN101027674A
(zh)
|
2004-09-23 |
2007-08-29 |
诺和诺德公司 |
自我照管支持设备
|
|
CN1276024C
(zh)
|
2004-09-30 |
2006-09-20 |
北京科技大学 |
含缺陷管道修复补强的碳纤维复合材料和方法
|
|
US20090285806A1
(en)
|
2004-10-05 |
2009-11-19 |
Martin Sinacore |
Methods and compositions for improving recombinant protein production
|
|
WO2006047670A2
(en)
|
2004-10-26 |
2006-05-04 |
Wyeth |
Methods for assessing antibodies to neurodegenerative disease-associated antigens
|
|
AU2005306502B2
(en)
|
2004-11-16 |
2012-11-15 |
Humanigen, Inc. |
Immunoglobulin variable region cassette exchange
|
|
PE20061401A1
(es)
|
2004-12-15 |
2006-12-23 |
Neuralab Ltd |
ANTICUERPOS Aß PARA MEJORAR LA COGNICION
|
|
WO2006066233A1
(en)
*
|
2004-12-15 |
2006-06-22 |
Neuralab Limited |
An immunoprecipitation-based assay for predicting in vivo efficacy of beta-amyloid antibodies
|
|
WO2006066118A2
(en)
|
2004-12-15 |
2006-06-22 |
Neuralab Limited |
Contextual fear test for predicting efficacy of alzheimer immunotherapeutic treatment
|
|
ES2434732T3
(es)
*
|
2004-12-15 |
2013-12-17 |
Janssen Alzheimer Immunotherapy |
Anticuerpos para beta-amiloide humanizados para su uso en mejorar la cognición
|
|
ES2396555T3
(es)
|
2004-12-15 |
2013-02-22 |
Janssen Alzheimer Immunotherapy |
Anticuerpos que reconocen péptido beta amiloide
|
|
WO2006081171A1
(en)
|
2005-01-24 |
2006-08-03 |
Amgen Inc. |
Humanized anti-amyloid antibody
|
|
JP2008528638A
(ja)
*
|
2005-01-28 |
2008-07-31 |
ワイス |
ポリペプチドの安定化液体処方
|
|
GT200600031A
(es)
*
|
2005-01-28 |
2006-08-29 |
|
Formulacion anticuerpo anti a beta
|
|
US7731962B2
(en)
|
2005-02-14 |
2010-06-08 |
Merck & Co., Inc. |
Anti-ADDL monoclonal antibody and use thereof
|
|
UY29504A1
(es)
|
2005-04-29 |
2006-10-31 |
Rinat Neuroscience Corp |
Anticuerpos dirigidos contra el péptido amiloide beta y métodos que utilizan los mismos.
|
|
MX2007013825A
(es)
|
2005-05-05 |
2008-01-18 |
Merck & Co Inc |
Composiciones de un conjugado peptidico y metodos para la prevencion y tratamiento de la enfermedad de alzheimer.
|
|
CA2611815A1
(en)
*
|
2005-06-17 |
2006-12-28 |
Elan Pharma International Limited |
Methods of purifying anti a beta antibodies
|
|
ATE550338T1
(de)
*
|
2005-07-18 |
2012-04-15 |
Merck Sharp & Dohme |
Spiropiperidininhibitoren von beta-secretase zur behandlung von alzheimer-krankheit
|
|
US8211648B2
(en)
|
2005-07-22 |
2012-07-03 |
Kalobios Pharmaceuticals, Inc. |
Secretion of antibodies without signal peptides from bacteria
|
|
EP1928916A2
(en)
|
2005-09-29 |
2008-06-11 |
Viral Logic Systems Technology Corp. |
Immunomodulatory compositions and uses therefor
|
|
EP1981305B1
(en)
|
2005-10-04 |
2013-06-26 |
Sharp Kabushiki Kaisha |
A paging method, a mobile station device and a base station device for executing the same
|
|
EP1951750A4
(en)
*
|
2005-11-10 |
2009-12-09 |
Roskamp Res Llc |
MODULATION OF THE ANGIOGENESIS BY A-BETA PEPTIDE FRAGMENTS
|
|
WO2007062088A1
(en)
|
2005-11-22 |
2007-05-31 |
The Trustees Of The University Of Pennsylvania |
Antibody treatment of alzheimer's and related diseases
|
|
MX358175B
(es)
|
2005-12-12 |
2018-08-08 |
Ac Immune Sa |
Anticuerpos monoclonales especificos 1-42 beta con propiedades terapeuticas.
|
|
EP1996621B1
(en)
|
2006-03-30 |
2009-12-09 |
Glaxo Group Limited |
Antibodies against amyloid-beta peptide
|
|
WO2010044803A1
(en)
|
2008-10-17 |
2010-04-22 |
Elan Pharma International Limited |
Treatment of amyloidogenic diseases
|
|
US8784810B2
(en)
|
2006-04-18 |
2014-07-22 |
Janssen Alzheimer Immunotherapy |
Treatment of amyloidogenic diseases
|
|
TWI305843B
(en)
*
|
2006-04-24 |
2009-02-01 |
Young Optics Inc |
Dlp projection apparatus
|
|
PL2468770T3
(pl)
|
2006-07-14 |
2018-07-31 |
Ac Immune S.A. |
Humanizowane przeciwciało przeciw amyloidowi beta
|
|
JP2010521651A
(ja)
|
2007-03-12 |
2010-06-24 |
独立行政法人放射線医学総合研究所 |
脳内のアミロイド関連神経炎症の画像化
|
|
US8003097B2
(en)
*
|
2007-04-18 |
2011-08-23 |
Janssen Alzheimer Immunotherapy |
Treatment of cerebral amyloid angiopathy
|
|
US20080292625A1
(en)
*
|
2007-04-18 |
2008-11-27 |
Sally Schroeter |
Prevention and treatment of cerebral amyloid angiopathy
|
|
SI2182983T1
(sl)
|
2007-07-27 |
2014-09-30 |
Janssen Alzheimer Immunotherapy |
Zdravljenje amiloidogenih bolezni s humaniziranimi protitelesi proti abeta
|
|
JO3076B1
(ar)
|
2007-10-17 |
2017-03-15 |
Janssen Alzheimer Immunotherap |
نظم العلاج المناعي المعتمد على حالة apoe
|
|
CN102016059B
(zh)
*
|
2007-12-28 |
2014-10-22 |
依兰制药公司 |
淀粉样变性的治疗和预防
|
|
MX349711B
(es)
|
2008-09-18 |
2017-08-09 |
Cedars Sinai Medical Center |
Método óptico para la detección de la enfermedad de alzheimer.
|
|
JP2013521233A
(ja)
|
2010-02-25 |
2013-06-10 |
ヤンセン アルツハイマー イミュノセラピー |
Ａβを標的とする免疫療法のＰＥＴモニタリング
|
|
EP2560681A4
(en)
|
2010-04-22 |
2013-09-25 |
Janssen Alzheimer Immunotherap |
USE OF TAU FOR MONITORING IMMUNOTHERAPY
|
|
US8689528B1
(en)
|
2011-11-08 |
2014-04-08 |
Seda Gaspari |
Method of packaging a plurality of tissues for dispensing
|