ATE546531T1 - Transaktivierungssystem für säugerzellen - Google Patents
Transaktivierungssystem für säugerzellenInfo
- Publication number
- ATE546531T1 ATE546531T1 AT04815827T AT04815827T ATE546531T1 AT E546531 T1 ATE546531 T1 AT E546531T1 AT 04815827 T AT04815827 T AT 04815827T AT 04815827 T AT04815827 T AT 04815827T AT E546531 T1 ATE546531 T1 AT E546531T1
- Authority
- AT
- Austria
- Prior art keywords
- mammal cells
- methods
- host cell
- desired polypeptide
- transactivation system
- Prior art date
Links
- 241000124008 Mammalia Species 0.000 title 1
- 230000023603 positive regulation of transcription initiation, DNA-dependent Effects 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 abstract 1
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 abstract 1
- 108091023040 Transcription factor Proteins 0.000 abstract 1
- 102000040945 Transcription factor Human genes 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 108091006106 transcriptional activators Proteins 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
Landscapes
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53391703P | 2003-12-31 | 2003-12-31 | |
| PCT/US2004/043830 WO2005065348A2 (en) | 2003-12-31 | 2004-12-30 | Transactivation system for mammalian cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE546531T1 true ATE546531T1 (de) | 2012-03-15 |
Family
ID=34748979
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04815827T ATE546531T1 (de) | 2003-12-31 | 2004-12-30 | Transaktivierungssystem für säugerzellen |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US8354251B2 (de) |
| EP (1) | EP1702071B1 (de) |
| AT (1) | ATE546531T1 (de) |
| WO (1) | WO2005065348A2 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7537930B2 (en) | 2004-07-23 | 2009-05-26 | Immunomedics, Inc. | Mammalian cell lines for increasing longevity and protein yield from a cell culture |
| DE602005027738D1 (de) * | 2004-11-18 | 2011-06-09 | Univ Hiroshima Nat Univ Corp | Verfahren und kit zur expression von protein unter regulation der expression von einer durch genamplifikation gebildeten wiederholungssequenz und transformant |
| AU2006249087B2 (en) | 2005-05-20 | 2012-05-17 | Lonza Biologics Plc | High-level expression of recombinant antibody in a mammalian host cell |
| US8357781B2 (en) | 2006-06-01 | 2013-01-22 | Janssen Alzheimer Immunotherapy | Neuroactive fragments of APP |
| EP2118270A2 (de) * | 2007-01-08 | 2009-11-18 | Millipore Corporation | Zellkulturverfahren für die produktion rekombinanter proteine bei verminderter konzentration von einem oder mehreren kontaminanten |
| JO3076B1 (ar) | 2007-10-17 | 2017-03-15 | Janssen Alzheimer Immunotherap | نظم العلاج المناعي المعتمد على حالة apoe |
| BR112012002974B1 (pt) | 2009-08-11 | 2022-06-07 | Genentech, Inc | Processo para produzir um anticorpo em uma célula hospedeira de célula ovário de hamster chinês (cho) expressando o referido polipeptídeo |
| CN105315370A (zh) | 2010-02-18 | 2016-02-10 | 加利福尼亚大学董事会 | 整合素αVβ8中和抗体 |
| KR102089121B1 (ko) * | 2013-03-14 | 2020-03-13 | 더 솔크 인스티튜트 포 바이올로지칼 스터디즈 | 종양살상형 아데노바이러스 조성물 |
| EP3198009B1 (de) * | 2014-09-24 | 2021-09-08 | Salk Institute for Biological Studies | Onkolytische tumorviren und verfahren zur verwendung |
| EP3390428B1 (de) | 2016-02-23 | 2019-09-25 | Salk Institute for Biological Studies | Test mit hohem durchsatz zur messung der adenovirusreplikationskinetik |
| JP7015551B2 (ja) | 2016-02-23 | 2022-02-15 | ソーク インスティテュート フォー バイオロジカル スタディーズ | ウイルス動態への影響を最小限にするための治療用アデノウイルスにおける外因性遺伝子発現 |
| JP7794421B2 (ja) | 2016-12-12 | 2026-01-06 | ソーク インスティテュート フォー バイオロジカル スタディーズ | 腫瘍を標的にする合成アデノウイルスおよびその使用 |
| BR112020019942A2 (pt) | 2018-04-09 | 2021-01-26 | Salk Institute For Biological Studies | composições de adenovírus oncolítico com propriedades de replicação aprimoradas |
| US20220193266A1 (en) * | 2019-04-30 | 2022-06-23 | Chan Zuckerberg Biohub, Inc. | A novel chromatin-opening element for stable long term gene expression |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8900483D0 (en) | 1989-01-10 | 1989-03-08 | Celltech Ltd | Recombinant dna method |
| US6274341B1 (en) | 1997-10-09 | 2001-08-14 | James E. Bailey | Cytostatic process increases the productivity of cultured cells |
| JP4220673B2 (ja) * | 1998-07-21 | 2009-02-04 | ミリポア・コーポレイション | 遍在性クロマチンオープニングエレメント（ｕｃｏｅ）を含むポリヌクレオチド |
| US6689606B2 (en) | 1998-07-21 | 2004-02-10 | M.L. Laboratories Plc | Polynucleotide |
| US6780639B1 (en) * | 1999-08-24 | 2004-08-24 | Universite Libre De Bruxelles | Antibiotic inducible/repressible genetic construct for gene therapy or gene immunization |
| AU2001259759A1 (en) * | 2000-05-12 | 2001-11-26 | Erik A. Whitehorn | Methods and compositions for amplifying intracellular signal transduction |
| ATE443131T1 (de) | 2001-07-10 | 2009-10-15 | Biogen Idec Inc | Hemmung des apoptoseprozesses und verbesserung der zelleistung |
-
2004
- 2004-12-30 AT AT04815827T patent/ATE546531T1/de active
- 2004-12-30 WO PCT/US2004/043830 patent/WO2005065348A2/en not_active Ceased
- 2004-12-30 EP EP04815827A patent/EP1702071B1/de not_active Expired - Lifetime
- 2004-12-30 US US10/585,149 patent/US8354251B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1702071B1 (de) | 2012-02-22 |
| WO2005065348A2 (en) | 2005-07-21 |
| EP1702071A2 (de) | 2006-09-20 |
| US20090111144A1 (en) | 2009-04-30 |
| EP1702071A4 (de) | 2007-07-25 |
| WO2005065348A3 (en) | 2005-10-27 |
| US8354251B2 (en) | 2013-01-15 |
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