ATE546531T1 - Transaktivierungssystem für säugerzellen - Google Patents
Transaktivierungssystem für säugerzellenInfo
- Publication number
- ATE546531T1 ATE546531T1 AT04815827T AT04815827T ATE546531T1 AT E546531 T1 ATE546531 T1 AT E546531T1 AT 04815827 T AT04815827 T AT 04815827T AT 04815827 T AT04815827 T AT 04815827T AT E546531 T1 ATE546531 T1 AT E546531T1
- Authority
- AT
- Austria
- Prior art keywords
- mammal cells
- methods
- host cell
- desired polypeptide
- transactivation system
- Prior art date
Links
- 241000124008 Mammalia Species 0.000 title 1
- 230000023603 positive regulation of transcription initiation, DNA-dependent Effects 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 abstract 1
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 abstract 1
- 108091023040 Transcription factor Proteins 0.000 abstract 1
- 102000040945 Transcription factor Human genes 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 108091006106 transcriptional activators Proteins 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
Landscapes
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53391703P | 2003-12-31 | 2003-12-31 | |
| PCT/US2004/043830 WO2005065348A2 (en) | 2003-12-31 | 2004-12-30 | Transactivation system for mammalian cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE546531T1 true ATE546531T1 (de) | 2012-03-15 |
Family
ID=34748979
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04815827T ATE546531T1 (de) | 2003-12-31 | 2004-12-30 | Transaktivierungssystem für säugerzellen |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US8354251B2 (de) |
| EP (1) | EP1702071B1 (de) |
| AT (1) | ATE546531T1 (de) |
| WO (1) | WO2005065348A2 (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7537930B2 (en) | 2004-07-23 | 2009-05-26 | Immunomedics, Inc. | Mammalian cell lines for increasing longevity and protein yield from a cell culture |
| EP1820856B1 (de) * | 2004-11-18 | 2011-04-27 | National University of Corporation Hiroshima University | Verfahren und kit zur expression von protein unter regulation der expression von einer durch genamplifikation gebildeten wiederholungssequenz und transformant |
| ES2864039T3 (es) | 2005-05-20 | 2021-10-13 | Lonza Biologics Plc | Expresión de alto nivel de un anticuerpo recombinante en una célula huésped de mamífero |
| JP2009538924A (ja) | 2006-06-01 | 2009-11-12 | エラン ファーマシューティカルズ，インコーポレイテッド | Ａｐｐの神経活性断片 |
| US8058027B2 (en) | 2007-01-08 | 2011-11-15 | Millipore Corporation | Cell culture methods for producing recombinant proteins in the presence of reduced levels of one or more contaminants |
| JO3076B1 (ar) | 2007-10-17 | 2017-03-15 | Janssen Alzheimer Immunotherap | نظم العلاج المناعي المعتمد على حالة apoe |
| KR20200111282A (ko) | 2009-08-11 | 2020-09-28 | 제넨테크, 인크. | 글루타민-비함유 세포 배양 배지에서의 단백질의 생성 |
| SG183356A1 (en) | 2010-02-18 | 2012-09-27 | Univ California | INTEGRIN aVß8 NEUTRALIZING ANTIBODY |
| AU2014236207B2 (en) | 2013-03-14 | 2019-05-23 | Salk Institute For Biological Studies | Oncolytic adenovirus compositions |
| PL3198009T3 (pl) * | 2014-09-24 | 2022-01-24 | Salk Institute For Biological Studies | Onkolityczne wirusy nowotworowe i sposoby zastosowania |
| JP7054527B2 (ja) | 2016-02-23 | 2022-04-14 | ソーク インスティテュート フォー バイオロジカル スタディーズ | アデノウイルスの複製動態を測定するための高スループットアッセイ |
| KR20220163505A (ko) | 2016-02-23 | 2022-12-09 | 솔크 인스티튜트 포 바이올로지칼 스터디즈 | 바이러스 동역학에 미치는 영향 최소화를 위한 치료용 아데노바이러스의 외인성 유전자 발현 |
| EP3532082A4 (de) | 2016-12-12 | 2020-08-26 | Salk Institute for Biological Studies | Auf tumoren gerichtete synthetische adenoviren und verwendungen davon |
| US20220193266A1 (en) * | 2019-04-30 | 2022-06-23 | Chan Zuckerberg Biohub, Inc. | A novel chromatin-opening element for stable long term gene expression |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8900483D0 (en) | 1989-01-10 | 1989-03-08 | Celltech Ltd | Recombinant dna method |
| US6274341B1 (en) | 1997-10-09 | 2001-08-14 | James E. Bailey | Cytostatic process increases the productivity of cultured cells |
| ES2375266T3 (es) * | 1998-07-21 | 2012-02-28 | Millipore Corporation | Un polinucleótido que comprende un elemento de apertura de cromatina ubicuo (ucoe). |
| AU771111B2 (en) * | 1998-07-21 | 2004-03-11 | Emd Millipore Corporation | A polynucleotide comprising a ubiquitous chromatin opening element (UCOE) |
| US6780639B1 (en) * | 1999-08-24 | 2004-08-24 | Universite Libre De Bruxelles | Antibiotic inducible/repressible genetic construct for gene therapy or gene immunization |
| AU2001259759A1 (en) * | 2000-05-12 | 2001-11-26 | Erik A. Whitehorn | Methods and compositions for amplifying intracellular signal transduction |
| AU2002315534B2 (en) | 2001-07-10 | 2008-05-22 | Biogen Idec Inc. | Inhibition of apoptosis process and improvement of cell performance |
-
2004
- 2004-12-30 US US10/585,149 patent/US8354251B2/en not_active Expired - Fee Related
- 2004-12-30 EP EP04815827A patent/EP1702071B1/de not_active Not-in-force
- 2004-12-30 AT AT04815827T patent/ATE546531T1/de active
- 2004-12-30 WO PCT/US2004/043830 patent/WO2005065348A2/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US20090111144A1 (en) | 2009-04-30 |
| EP1702071A2 (de) | 2006-09-20 |
| US8354251B2 (en) | 2013-01-15 |
| EP1702071B1 (de) | 2012-02-22 |
| WO2005065348A2 (en) | 2005-07-21 |
| WO2005065348A3 (en) | 2005-10-27 |
| EP1702071A4 (de) | 2007-07-25 |
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