ATE302282T1 - Erhöhte herstellung von sekretierten proteinen durch rekombinante hefezellen - Google Patents

Erhöhte herstellung von sekretierten proteinen durch rekombinante hefezellen

Info

Publication number
ATE302282T1
ATE302282T1 AT98933668T AT98933668T ATE302282T1 AT E302282 T1 ATE302282 T1 AT E302282T1 AT 98933668 T AT98933668 T AT 98933668T AT 98933668 T AT98933668 T AT 98933668T AT E302282 T1 ATE302282 T1 AT E302282T1
Authority
AT
Austria
Prior art keywords
yeast cells
recombinant yeast
increased production
secreted proteins
seb1
Prior art date
Application number
AT98933668T
Other languages
English (en)
Inventor
Sirkka Keraenen
Jaana Toikkanen
Ville Tieaho
Hans Soederlund
Original Assignee
Valtion Teknillinen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Valtion Teknillinen filed Critical Valtion Teknillinen
Application granted granted Critical
Publication of ATE302282T1 publication Critical patent/ATE302282T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Seeds, Soups, And Other Foods (AREA)
AT98933668T 1997-07-09 1998-07-08 Erhöhte herstellung von sekretierten proteinen durch rekombinante hefezellen ATE302282T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI972909A FI972909A0 (fi) 1997-07-09 1997-07-09 Oekad produktion av avsoendrade proteiner genom rekombinatjaestceller
PCT/FI1998/000576 WO1999002716A1 (en) 1997-07-09 1998-07-08 Increased production of secreted proteins by recombinant yeast cells

Publications (1)

Publication Number Publication Date
ATE302282T1 true ATE302282T1 (de) 2005-09-15

Family

ID=8549223

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98933668T ATE302282T1 (de) 1997-07-09 1998-07-08 Erhöhte herstellung von sekretierten proteinen durch rekombinante hefezellen

Country Status (11)

Country Link
US (1) US6344341B1 (de)
EP (1) EP0994955B1 (de)
JP (1) JP2001509392A (de)
AT (1) ATE302282T1 (de)
AU (1) AU734541B2 (de)
CA (1) CA2296084A1 (de)
DE (1) DE69831242T2 (de)
DK (1) DK0994955T3 (de)
ES (1) ES2247704T3 (de)
FI (1) FI972909A0 (de)
WO (1) WO1999002716A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4896013B2 (ja) * 2004-06-16 2012-03-14 ディーエスエム アイピー アセッツ ビー．ブイ． 改良された分泌によるポリペプチドの製造
EP2511372A1 (de) * 2006-11-02 2012-10-17 DSM IP Assets B.V. Verbesserte Herstellung von sekretierten Proteinen durch filamentöse Pilze
AR086200A1 (es) * 2011-04-22 2013-11-27 Danisco Us Inc Hongos filamentosos que tienen un fenotipo de viscosidad alterado
WO2015158800A1 (en) * 2014-04-17 2015-10-22 Boehringer Ingelheim Rcv Gmbh & Co Kg Recombinant host cell for expressing proteins of interest
US10865416B2 (en) * 2014-04-17 2020-12-15 Boehringer Ingelheim Rcv Gmbh & Co Kg Recombinant host cell engineered to overexpress helper proteins

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE103333T1 (de) 1987-03-23 1994-04-15 Zymogenetics Inc Hohe proteinsyntheserate in hefe.

Also Published As

Publication number Publication date
ES2247704T3 (es) 2006-03-01
FI972909A0 (fi) 1997-07-09
DK0994955T3 (da) 2005-11-28
EP0994955A1 (de) 2000-04-26
CA2296084A1 (en) 1999-01-21
AU8341098A (en) 1999-02-08
US6344341B1 (en) 2002-02-05
EP0994955B1 (de) 2005-08-17
DE69831242T2 (de) 2006-06-29
WO1999002716A1 (en) 1999-01-21
JP2001509392A (ja) 2001-07-24
AU734541B2 (en) 2001-06-14
DE69831242D1 (de) 2005-09-22

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