EA199900483A1 - δ-ЭНДОТОКСИНЫ ШИРОКОГО СПЕКТРА ДЕЙСТВИЯ - Google Patents

δ-ЭНДОТОКСИНЫ ШИРОКОГО СПЕКТРА ДЕЙСТВИЯ

Info

Publication number
EA199900483A1
EA199900483A1 EA199900483A EA199900483A EA199900483A1 EA 199900483 A1 EA199900483 A1 EA 199900483A1 EA 199900483 A EA199900483 A EA 199900483A EA 199900483 A EA199900483 A EA 199900483A EA 199900483 A1 EA199900483 A1 EA 199900483A1
Authority
EA
Eurasian Patent Office
Prior art keywords
presented
methods
host cells
endotoxins
action
Prior art date
Application number
EA199900483A
Other languages
English (en)
Inventor
Томас Малвар
Эми Джелен Гилмер
Original Assignee
Экоджен, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Экоджен, Инк. filed Critical Экоджен, Инк.
Priority claimed from PCT/US1997/021587 external-priority patent/WO1998022595A1/en
Publication of EA199900483A1 publication Critical patent/EA199900483A1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
    • C07K14/325—Bacillus thuringiensis crystal protein (delta-endotoxin)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8286—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for insect resistance
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Insects & Arthropods (AREA)
  • Pest Control & Pesticides (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Представлены новые, искусственно модифицированные химерные кристалловидные белки В.thuringiensis, характеризующиеся улучшенной инсектицидной активностью по отношению к жесткокрылым, двукрылым и чешуекрылым насекомым. Также представлены сегменты нуклеиновой кислоты, кодирующие эти новые пептиды. Представлены методы формирования и использования этих генов, так же, как и методы рекомбинантной экспрессии и трансформации подходящих клеток-хозяев. Также аспектами изобретения являются трансформированные клетки-хозяева и трансгенные растения, экспрессирующие модифицированный эндотоксин.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA199900483A 1996-11-20 1997-11-20 δ-ЭНДОТОКСИНЫ ШИРОКОГО СПЕКТРА ДЕЙСТВИЯ EA199900483A1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/754,490 US6017534A (en) 1996-11-20 1996-11-20 Hybrid Bacillus thuringiensis δ-endotoxins with novel broad-spectrum insecticidal activity
US08/922,505 US6110464A (en) 1996-11-20 1997-09-03 Broad-spectrum δ-endotoxins
PCT/US1997/021587 WO1998022595A1 (en) 1996-11-20 1997-11-20 Broad-spectrum delta-endotoxins

Publications (1)

Publication Number Publication Date
EA199900483A1 true EA199900483A1 (ru) 2000-06-26

Family

ID=25035035

Family Applications (1)

Application Number Title Priority Date Filing Date
EA199900483A EA199900483A1 (ru) 1996-11-20 1997-11-20 δ-ЭНДОТОКСИНЫ ШИРОКОГО СПЕКТРА ДЕЙСТВИЯ

Country Status (5)

Country Link
US (10) US6017534A (ru)
AR (2) AR011013A1 (ru)
CO (1) CO4700555A1 (ru)
EA (1) EA199900483A1 (ru)
ZA (1) ZA9710429B (ru)

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