CO4700555A1 - Endotoxinas de amplio espectro - Google Patents

Endotoxinas de amplio espectro

Info

Publication number
CO4700555A1
CO4700555A1 CO97067618A CO97067618A CO4700555A1 CO 4700555 A1 CO4700555 A1 CO 4700555A1 CO 97067618 A CO97067618 A CO 97067618A CO 97067618 A CO97067618 A CO 97067618A CO 4700555 A1 CO4700555 A1 CO 4700555A1
Authority
CO
Colombia
Prior art keywords
seq
polypeptide
nucleic acid
acid segment
cell
Prior art date
Application number
CO97067618A
Other languages
English (en)
Inventor
Thomas Malvar
Gilmer Amy Jelen
Original Assignee
Ecogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ecogen Inc filed Critical Ecogen Inc
Publication of CO4700555A1 publication Critical patent/CO4700555A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
    • C07K14/325—Bacillus thuringiensis crystal peptides, i.e. delta-endotoxins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8286—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for insect resistance
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Insects & Arthropods (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Un segmento de ácido nucleico aislado que codifica unpolipéptido, caracterizado porque comprende las secuencias de aminoácidos de la SEQ ID No. 10, SEQ ID No. 12, SEQ ID No. 14, SEQ ID No. 26, SEQ ID No. 28, SEQ ID No. 30 o SEQ ID No. 34. El segmento de ácido nucleico de la cláusula 1, caracterizado porque dicho segmento de ácido nucléico codifica un polipéptido que presenta actividad insecticida contra Spodoptera frugiperda, Spodoptera exigua, Heliothis virescens, Helicoverpa Zea u Ostrinia nubilalis. 1Una célula huésped, caracterizada porque comprende un segmento de ácido nucléico acorde con cualquiera de las cláusulas 1 a 12. 3Una composición que contiene un polipéptido que se puede preparar por un proceso que comprende los pasos de: (a) cultivar una célula de la cepa NRRL B-21579, NRRL B-21580, EG11768, EG11090, EG11063, EG11074, EG11092, EG11735 o EG 11751 de B.thuringiensis bajo condiciones efectivas como para producir una composición que contenga un polipéptido de B.thuringiensis; y (b) obtener dicha composición a partir de dicha célula. 4Una planta transgénica que incorporó en su genoma un transgen que codifica un polipéptido, caracterizada porque comprende la secuencia de aminoácidos de la SEQ ID No. 10, SEQ ID No. 12, SEQ ID No. 14, SEQ ID No. 26, SEQ ID No. 28, SEQ ID No. 30 o SEQ ID No. 34.
CO97067618A 1996-11-20 1997-11-19 Endotoxinas de amplio espectro CO4700555A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/754,490 US6017534A (en) 1996-11-20 1996-11-20 Hybrid Bacillus thuringiensis δ-endotoxins with novel broad-spectrum insecticidal activity
US08/922,505 US6110464A (en) 1996-11-20 1997-09-03 Broad-spectrum δ-endotoxins

Publications (1)

Publication Number Publication Date
CO4700555A1 true CO4700555A1 (es) 1998-12-29

Family

ID=25035035

Family Applications (1)

Application Number Title Priority Date Filing Date
CO97067618A CO4700555A1 (es) 1996-11-20 1997-11-19 Endotoxinas de amplio espectro

Country Status (5)

Country Link
US (10) US6017534A (es)
AR (2) AR011013A1 (es)
CO (1) CO4700555A1 (es)
EA (1) EA199900483A1 (es)
ZA (1) ZA9710429B (es)

Families Citing this family (176)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6017534A (en) * 1996-11-20 2000-01-25 Ecogen, Inc. Hybrid Bacillus thuringiensis δ-endotoxins with novel broad-spectrum insecticidal activity
BR9713373A (pt) * 1996-11-20 2001-06-19 Ecogen Inc Delta-endotoxinas de amplo espectro
US6713063B1 (en) * 1996-11-20 2004-03-30 Monsanto Technology, Llc Broad-spectrum δ-endotoxins
WO2001083825A2 (en) * 2000-05-04 2001-11-08 The Center For Blood Research, Inc. Colloid compositions for solid phase biomolecular analytical systems
EP1988099B1 (en) 2001-01-09 2012-11-14 Bayer CropScience NV Bacillus thuringiensis insecticidal proteins
JP4775929B2 (ja) * 2002-02-13 2011-09-21 ピーピージー インダストリーズ オハイオ，インコーポレイテッド 基材上に多層複合コーティングを形成するためのコーティングラインおよびプロセス
CN100497378C (zh) 2002-03-22 2009-06-10 拜尔生物科学公司 新的苏云金芽孢杆菌杀昆虫蛋白质
US7053266B2 (en) * 2002-03-27 2006-05-30 Council Of Scientfic And Industrial Research Chimeric cry1E δendotoxin and methods of controlling insects
CN100403028C (zh) * 2002-05-31 2008-07-16 印度农业研究委员会 Bt-cry毒素的迅速检测
CA2851035C (en) 2002-07-18 2018-05-29 Stanislaw Flasinski Methods for using artificial polynucleotides and compositions thereof to reduce transgene silencing
CN102586285B (zh) * 2003-02-20 2016-01-13 阿则耐克斯公司 δ-内毒素基因及其使用方法
US7297678B2 (en) * 2003-03-12 2007-11-20 Genencor International, Inc. Use of repeat sequence protein polymers in personal care compositions
WO2004080426A2 (en) * 2003-03-12 2004-09-23 Dow Corning Corporation Use of repeat sequence protein polymers in personal care compositions
EP2116606B1 (en) 2003-03-28 2012-12-19 Monsanto Technology, LLC Novel plant promoters for use in early seed development
CO5450254A1 (es) * 2003-04-01 2004-10-29 Corporacion Para Investigacion Peptido sintetico que posee una actividad ionorfica y antimicrobiana
US7511130B2 (en) 2003-08-25 2009-03-31 Monsanto Technology Llc Chimeric rice Os-TubA-3 promoter and methods of use
US7393922B2 (en) * 2003-08-29 2008-07-01 The Ohio State University Research Foundation Insecticidal Cry4Ba proteins with enhanced toxicity
AR046991A1 (es) * 2003-12-23 2006-01-04 Maharashtra Hybrid Seeds Compa Metodo para la preparacion de un soporte solido listo para usar para ensayo inmunosorbente ligado a enzima (elisa) rapido
US7371848B2 (en) 2004-01-20 2008-05-13 Monsanto Technology Llc Chimeric promoters comprising a caulimovirus promoter enhancer for use in plants
WO2005094340A2 (en) * 2004-03-29 2005-10-13 Pioneer Hi-Bred International, Inc. Method of reducing insect resistant pests in transgenic crops
EP1788861B1 (en) 2004-08-24 2017-04-12 Monsanto Technology, LLC Adenylate translocator protein gene non-coding regulatory elements for use in plants
EP2003206A1 (en) 2004-09-14 2008-12-17 Monsanto Technology, LLC Promoter molecules for use in plants
KR100657013B1 (ko) 2004-11-25 2006-12-12 이동현 살충성과 항진균성을 동시에 갖는 신규한 바실러스 츄린겐시스 아종 소또 00-fz46-12(kctc10717bp) 및 이를 이용한 살충 및 살진균 방법
EP1856264B1 (en) 2005-02-26 2014-07-23 BASF Plant Science GmbH Expression cassettes for seed-preferential expression in plants
CA2606220A1 (en) 2005-04-19 2006-12-21 Basf Plant Science Gmbh Starchy-endosperm and/or germinating embryo-specific expression in mono-cotyledonous plants
AU2006245701B2 (en) 2005-05-10 2011-04-28 Basf Plant Science Gmbh Expression cassettes for seed-preferential expression in plants
US8173871B2 (en) 2005-07-08 2012-05-08 Universidad Nacional Autonoma De Mexico Bacterial proteins with pesticidal activity
KR101156893B1 (ko) 2005-08-31 2012-06-21 몬산토 테크놀로지 엘엘씨 살충 단백질을 암호화하는 뉴클레오티드 서열들
US8993846B2 (en) 2005-09-06 2015-03-31 Monsanto Technology Llc Vectors and methods for improved plant transformation efficiency
US7294768B1 (en) 2005-09-27 2007-11-13 Monsanto Technology Llc Soybean variety 0384279
PL1947926T3 (pl) 2005-10-28 2015-08-31 Dow Agrosciences Llc Nowe geny odporności na herbicydy
CA2637588A1 (en) 2006-02-17 2007-08-30 Monsanto Technology Llc Chimeric regulatory sequences comprising introns from dicotyledons for plant gene expression
EP2021476B1 (en) 2006-05-26 2014-07-09 Monsanto Technology, LLC Corn plant and seed corresponding to transgenic event mon89034 and methods for detection and use thereof
US20110035840A1 (en) 2007-02-16 2011-02-10 Basf Plant Science Gmbh Nucleic acid sequences for regulation of embryo-specific expression in monocotyledoneous plants
US7838729B2 (en) 2007-02-26 2010-11-23 Monsanto Technology Llc Chloroplast transit peptides for efficient targeting of DMO and uses thereof
US8260783B2 (en) * 2007-02-27 2012-09-04 Siemens Aktiengesellschaft Storage of multiple, related time-series data streams
MX2009010062A (es) * 2007-03-28 2009-10-13 Syngenta Participations Ag Proteinas insecticidas.
US8609936B2 (en) 2007-04-27 2013-12-17 Monsanto Technology Llc Hemipteran-and coleopteran active toxin proteins from Bacillus thuringiensis
ES2457218T3 (es) 2008-04-07 2014-04-25 Monsanto Technology Llc Elementos reguladores de plantas y usos de los mismos
WO2009132850A1 (en) * 2008-05-01 2009-11-05 Bayer Bioscience N.V. Armyworm insect resistance management in transgenic plants
CA3008307C (en) * 2008-06-25 2020-12-15 Athenix Corp. Toxin genes and methods for their use
EP2315527A4 (en) * 2008-08-13 2013-03-06 James Messina WIDE SPECTRUM ANIMAL REPELLENT AND METHOD
US8216997B2 (en) 2008-08-14 2012-07-10 Acceleron Pharma, Inc. Methods for increasing red blood cell levels and treating anemia using a combination of GDF traps and erythropoietin receptor activators
TWI784538B (zh) 2008-08-14 2022-11-21 美商艾瑟勒朗法瑪公司 使用ｇｄｆ阱以增加紅血球水平
WO2010099431A2 (en) 2009-02-27 2010-09-02 Monsanto Technology Llc Hydroponic apparatus and methods of use
EP2405834B1 (en) 2009-03-10 2016-07-20 Stryker European Holdings I, LLC External fixation system
ES2532145T3 (es) * 2009-04-17 2015-03-24 Dow Agrosciences Llc Toxinas Cry insecticidas DIG-3
WO2011003901A1 (en) 2009-07-10 2011-01-13 Basf Plant Science Company Gmbh Expression cassettes for endosperm-specific expression in plants
US8937214B2 (en) 2009-10-23 2015-01-20 Monsanto Technology Llc Methods and compositions for expression of transgenes in plants
AU2010325720A1 (en) 2009-12-03 2012-07-19 Basf Plant Science Company Gmbh Expression cassettes for embryo-specific expression in plants
UA112286C2 (uk) 2009-12-16 2016-08-25 ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі МОДИФІКОВАНИЙ ІНСЕКТИЦИДНИЙ БІЛОК CRY1Са ТА СПОСІБ БОРОТЬБИ З ЛУСКОКРИЛИМИ КОМАХАМИ З ЙОГО ВИКОРИСТАННЯМ
BR112012015697A2 (pt) 2009-12-23 2015-08-25 Bayer Intelectual Property Gmbh Plantas tolerantes a herbicidas inibidores de hppd.
AR079972A1 (es) 2009-12-23 2012-03-07 Bayer Cropscience Ag Plantas tolerantes a herbicidas inhibidores de las hppd
EA201290560A1 (ru) 2009-12-23 2014-05-30 Байер Интеллектуэль Проперти Гмбх Растения, устойчивые к гербицидам - ингибиторам hppd
ES2668198T3 (es) 2009-12-23 2018-05-17 Bayer Intellectual Property Gmbh Plantas tolerantes a herbicidas inhibidores de HPPD
CA2785225C (en) 2009-12-23 2019-01-22 Bayer Intellectual Property Gmbh Plants tolerant to hppd inhibitor herbicides.
ES2736037T3 (es) 2010-01-14 2019-12-23 Monsanto Technology Llc Elementos reguladores de las plantas y usos de los mismos
US8735560B1 (en) 2010-03-02 2014-05-27 Monsanto Technology Llc Multiple domain lepidopteran active toxin proteins
US9234208B1 (en) 2010-05-10 2016-01-12 Dow Agrosciences Llc DIG-13 insecticidal cry toxins
AU2011296209B2 (en) 2010-08-30 2015-07-02 Dow Agrosciences Llc Sugarcane bacilliform viral (SCBV) enhancer and its use in plant functional genomics
EP2669373B1 (en) 2010-11-10 2016-06-01 Bayer CropScience AG HPPD variants and methods of use
MX2011000894A (es) * 2010-12-17 2012-06-18 Ct De Investigacion Cientifica Y De Educacion Superior De Ensenada B C Proteinas cry insecticidas de bacilus thuringiensis con actividad anticancerígena.
AU2012234449B2 (en) 2011-03-25 2016-05-12 Bayer Intellectual Property Gmbh Use of N-(tetrazol-4-yl)- or N-(triazol-3-yl)arylcarboxamides or their salts for controlling unwanted plants in areas of transgenic crop plants being tolerant to hppd inhibitor herbicides
CA3004022C (en) 2011-03-25 2020-07-28 Monsanto Technology Llc Plant regulatory elements and uses thereof
WO2012130684A1 (en) 2011-03-25 2012-10-04 Bayer Cropscience Ag Use of n-(1,2,5-oxadiazol-3-yl)benzamides for controlling unwanted plants in areas of transgenic crop plants being tolerant to hppd inhibitor herbicides
KR102080055B1 (ko) 2011-05-13 2020-02-24 몬산토 테크놀로지 엘엘씨 식물 조절 요소 및 그의 용도
BR102012019434B1 (pt) * 2011-07-26 2021-11-09 Dow Agrosciences Llc Métodos de controle de pestes, de insetos, molécula e sequência de dna diagnóstica para o evento de soja 9582.814.19.1
US9271486B2 (en) 2011-11-10 2016-03-01 James J. Messina Combination animal repellents
EP2820136B1 (en) 2012-02-29 2018-03-28 Dow AgroSciences LLC Sugarcane bacilliform viral (scbv) enhancer and its use in plant functional genomics
US9567381B2 (en) 2012-03-09 2017-02-14 Vestaron Corporation Toxic peptide production, peptide expression in plants and combinations of cysteine rich peptides
US11692016B2 (en) 2012-03-09 2023-07-04 Vestaron Corporation High gene expression yeast strain
US9663793B2 (en) 2012-04-20 2017-05-30 Monsanto Technology, Llc Plant regulatory elements and uses thereof
US20150211019A1 (en) 2012-08-13 2015-07-30 University Of Georgia Research Foundation, Inc. Compositions and Methods for Increasing Pest Resistance in Plants
US10793872B2 (en) 2012-09-14 2020-10-06 BASF Agricultural Solutions Seed US LLC HPPD variants and methods of use
US9783820B2 (en) 2012-10-15 2017-10-10 Pioneer Hi-Bred International, Inc. Methods and compositions to enhance activity of Cry endotoxins
WO2014071182A1 (en) 2012-11-01 2014-05-08 Massachusetts Institute Of Technology Directed evolution of synthetic gene cluster
AP2015008825A0 (en) 2012-12-19 2015-10-31 Monsanto Technology Llc Plant regulatory elements and uses thereof
AU2014225732B2 (en) 2013-03-07 2020-03-19 BASF Agricultural Solutions Seed US LLC Toxin genes and methods for their use
BR122020011572B1 (pt) 2013-03-14 2021-10-13 Monsanto Technology Llc Cassete de expressão compreendendo elemento regulador de planta e método para produzir uma planta transgênica
CN107699563B (zh) 2013-03-14 2022-02-22 孟山都技术有限公司 植物调控元件和其用途
CA3200166A1 (en) 2013-03-14 2014-09-25 Pioneer Hi-Bred International, Inc. Compositions and methods to control insect pests
CA2901316A1 (en) 2013-03-15 2014-09-25 Pioneer Hi-Bred International, Inc. Phi-4 polypeptides and methods for their use
EP3296403A1 (en) 2013-06-14 2018-03-21 Monsanto Technology LLC Soybean transgenic event mon87751 and methods for detection and use thereof
WO2015023846A2 (en) 2013-08-16 2015-02-19 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
ES2937045T3 (es) 2013-09-13 2023-03-23 Pioneer Hi Bred Int Proteínas insecticidas y métodos para su uso
WO2015120270A1 (en) 2014-02-07 2015-08-13 Pioneer Hi Bred International, Inc. Insecticidal proteins and methods for their use
MX2016010187A (es) 2014-02-07 2017-07-11 Pioneer Hi Bred Int Proteinas insecticidas y metodos para su uso.
MX2016011745A (es) 2014-03-11 2017-09-01 Bayer Cropscience Lp Variantes de hppd y metodos de uso.
WO2015148976A1 (en) 2014-03-28 2015-10-01 Monsanto Technology Llc Pesticidal toxin proteins active against coleopteran insects
CA2946848A1 (en) * 2014-04-29 2015-11-05 Dow Agrosciences Llc Monoclonal antibodies specific for cry1ca and related detection methods
WO2016000237A1 (en) 2014-07-03 2016-01-07 Pioneer Overseas Corporation Plants having enhanced tolerance to insect pests and related constructs and methods involving insect tolerance genes
US20170247719A1 (en) 2014-09-17 2017-08-31 Pioneer Hi-Bred International, Inc. Compositions and methods to control insect pests
US10487123B2 (en) 2014-10-16 2019-11-26 Monsanto Technology Llc Chimeric insecticidal proteins toxic or inhibitory to lepidopteran pests
BR112017007932A2 (pt) 2014-10-16 2018-01-23 Du Pont proteínas inseticidas e métodos para uso das mesmas
EP3207049B1 (en) 2014-10-16 2021-01-27 Monsanto Technology LLC Novel chimeric insecticidal proteins toxic or inhibitory to lepidopteran pests
WO2016061392A1 (en) 2014-10-16 2016-04-21 Monsanto Technology Llc Proteins toxic or inhibitory to lepidopteran insects
UA123036C2 (uk) 2014-10-16 2021-02-03 Монсанто Текнолоджі Ллс Сконструйований інсектицидний білок, який має активність проти лускокрилих
WO2016077052A2 (en) 2014-10-22 2016-05-19 President And Fellows Of Harvard College Evolution of proteases
TW201615095A (zh) 2014-10-31 2016-05-01 陶氏農業科學公司 Ｄｉｇ－３０３殺蟲ｃｒｙ毒素
BR122020006739B1 (pt) 2014-11-20 2024-01-23 Monsanto Technology Llc Cassete de expressão, célula hospedeira bacteriana, composição inibidora de inseto, método para controlar uma praga de espécie coleoptera, e vetor recombinante
US11130964B2 (en) 2014-11-20 2021-09-28 Monsanto Technology Llc Insect inhibitory proteins
CA2977026A1 (en) 2015-03-11 2016-09-15 E.I. Du Pont De Nemours And Company Insecticidal combinations of pip-72 and methods of use
EP3274462A4 (en) 2015-03-26 2018-12-26 The Texas A&M University System Conversion of lignin into bioplastics and lipid fuels
WO2016168631A1 (en) 2015-04-17 2016-10-20 President And Fellows Of Harvard College Vector-based mutagenesis system
CN116333064A (zh) 2015-05-19 2023-06-27 先锋国际良种公司 杀昆虫蛋白及其使用方法
WO2016205445A1 (en) 2015-06-16 2016-12-22 Pioneer Hi-Bred International, Inc. Compositions and methods to control insect pests
KR102594707B1 (ko) 2015-07-13 2023-10-26 피벗 바이오, 인크. 식물 형질 개선을 위한 방법 및 조성물
US11524983B2 (en) 2015-07-23 2022-12-13 President And Fellows Of Harvard College Evolution of Bt toxins
WO2017019895A1 (en) 2015-07-30 2017-02-02 President And Fellows Of Harvard College Evolution of talens
EP3943602A1 (en) 2015-08-06 2022-01-26 Pioneer Hi-Bred International, Inc. Plant derived insecticidal proteins and methods for their use
US10155960B2 (en) 2015-08-27 2018-12-18 Monsanto Technology Llc Insect inhibitory proteins
CA2992488A1 (en) 2015-08-28 2017-03-09 Pioneer Hi-Bred International, Inc. Ochrobactrum-mediated transformation of plants
EP3347475B1 (en) 2015-09-11 2022-11-16 BASF Agricultural Solutions Seed US LLC Hppd variants and methods of use
BR112018006800A2 (pt) 2015-10-05 2018-10-23 Massachusetts Inst Technology fixação de nitrogênio usando agrupamento (cluster)s nif reestruturados
US20180325119A1 (en) 2015-12-18 2018-11-15 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
SG10202006263UA (en) 2016-03-11 2020-08-28 Monsanto Technology Llc Plant regulatory elements and uses thereof
US11781151B2 (en) 2016-04-14 2023-10-10 Pioneer Hi-Bred International, Inc. Insecticidal CRY1B variants having improved activity spectrum and uses thereof
CN109072249B (zh) 2016-04-19 2023-08-18 先锋国际良种公司 具有改善的活性谱的多肽的杀昆虫组合及其用途
EP3960863A1 (en) 2016-05-04 2022-03-02 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
KR102374017B1 (ko) 2016-05-24 2022-03-14 몬산토 테크놀로지 엘엘씨 식물 조절 요소 및 이들의 용도
CA3022858A1 (en) 2016-06-16 2017-12-21 Pioneer Hi-Bred International, Inc. Compositions and methods to control insect pests
EP4083215A1 (en) 2016-06-24 2022-11-02 Pioneer Hi-Bred International, Inc. Plant regulatory elements and methods of use thereof
CA3029271A1 (en) 2016-06-28 2018-01-04 Cellectis Altering expression of gene products in plants through targeted insertion of nucleic acid sequences
MX2018015906A (es) 2016-07-01 2019-04-04 Pioneer Hi Bred Int Proteinas insecticidas de plantas y metodos para sus usos.
US20210292778A1 (en) 2016-07-12 2021-09-23 Pioneer Hi-Bred International, Inc. Compositions and methods to control insect pests
KR20190085514A (ko) 2016-10-21 2019-07-18 베스타론 코포레이션 절단성 펩타이드 및 이를 포함하는 살충 및 살선충 단백질
EP3535285B1 (en) 2016-11-01 2022-04-06 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
CA3043493A1 (en) 2016-11-23 2018-05-31 BASF Agricultural Solutions Seed US LLC Axmi669 and axmi991 toxin genes and methods for their use
CN110088123B (zh) 2016-12-14 2023-10-20 先锋国际良种公司 杀昆虫蛋白及其使用方法
JP2020504609A (ja) 2016-12-22 2020-02-13 ビーエーエスエフ アグリカルチュラル ソリューションズ シード ユーエス エルエルシー 有害線虫の防除のためのｃｒｙ１４の使用
US11213028B2 (en) 2016-12-22 2022-01-04 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
UY37566A (es) 2017-01-12 2018-07-31 Pivot Bio Inc Métodos y composiciones para mejorar características en plantas
UY37570A (es) 2017-01-18 2018-08-31 Bayer Cropscience Lp Uso de bp005 para el control de patógenos de planta
CA3049775A1 (en) 2017-01-18 2018-07-26 BASF Agricultural Solutions Seed US LLC Bp005 toxin gene and methods for its use
WO2018140214A1 (en) 2017-01-24 2018-08-02 Pioneer Hi-Bred International, Inc. Nematicidal protein from pseudomonas
MX2019009371A (es) 2017-02-08 2019-09-23 Pionner Hi Bred Int Inc Combinaciones insecticidas de proteinas insecticidas derivadas de plantas y metodos para su uso.
WO2018165091A1 (en) 2017-03-07 2018-09-13 Bayer Cropscience Lp Hppd variants and methods of use
MX2019013321A (es) 2017-05-11 2020-02-10 Pioneer Hi Bred Int Proteinas insecticidas y metodos para su uso.
WO2018217333A1 (en) 2017-05-26 2018-11-29 Pioneer Hi-Bred International, Inc. Insecticidal polypeptides having improved activity spectrum and uses thereof
US11447809B2 (en) 2017-07-06 2022-09-20 President And Fellows Of Harvard College Evolution of tRNA synthetases
US11624130B2 (en) 2017-09-18 2023-04-11 President And Fellows Of Harvard College Continuous evolution for stabilized proteins
US20200165626A1 (en) 2017-10-13 2020-05-28 Pioneer Hi-Bred International, Inc. Virus-induced gene silencing technology for insect control in maize
US20210032651A1 (en) 2017-10-24 2021-02-04 Basf Se Improvement of herbicide tolerance to hppd inhibitors by down-regulation of putative 4-hydroxyphenylpyruvate reductases in soybean
US11279944B2 (en) 2017-10-24 2022-03-22 BASF Agricultural Solutions Seed US LLC Of herbicide tolerance to 4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibitors by down-regulation of HPPD expression in soybean
AU2018354221A1 (en) 2017-10-25 2020-05-14 Pivot Bio, Inc. Methods and compositions for improving engineered microbes that fix nitrogen
CA3085324A1 (en) 2017-12-15 2019-06-20 Syngenta Participations Ag Non-antibody ligands for detecting target proteins
WO2019139616A1 (en) 2018-01-12 2019-07-18 The Texas A&M University System Increasing plant bioproduct yield
KR20200123144A (ko) 2018-02-22 2020-10-28 지머젠 인코포레이티드 바실러스가 농축된 게놈 라이브러리를 생성하고 새로운 cry 독소를 동정하기 위한 방법
JP2021514643A (ja) 2018-03-02 2021-06-17 ザイマージェン インコーポレイテッド 殺虫タンパク質発見プラットフォームおよびそこから発見される殺虫タンパク質
WO2019169150A1 (en) 2018-03-02 2019-09-06 Pioneer Hi-Bred International, Inc. Plant health assay
US11702668B2 (en) 2018-05-22 2023-07-18 Pioneer Hi-Bred International, Inc. Plant regulatory elements and methods of use thereof
WO2019241649A1 (en) 2018-06-14 2019-12-19 President And Fellows Of Harvard College Evolution of cytidine deaminases
BR112020026771A2 (pt) 2018-06-27 2021-03-30 Pivot Bio, Inc. Composições agrícolas que compreendem micróbios de fixação de nitrogênio remodelados
MX2021002290A (es) 2018-08-29 2021-04-28 Pioneer Hi Bred Int Proteinas insecticidas y metodos para su uso.
EP3927168A4 (en) * 2019-02-20 2023-02-08 Syngenta Crop Protection AG ENGINEERED PESTICIDE PROTEINS AND METHODS TO CONTROL PLANT PESTS
WO2021076346A1 (en) 2019-10-18 2021-04-22 Pioneer Hi-Bred International, Inc. Maize event dp-202216-6 and dp-023211-2 stack
WO2021221690A1 (en) 2020-05-01 2021-11-04 Pivot Bio, Inc. Modified bacterial strains for improved fixation of nitrogen
TW202142114A (zh) 2020-02-04 2021-11-16 美商陶氏農業科學公司 具有殺有害生物效用之組成物及與其相關之方法
CA3172322A1 (en) 2020-05-01 2021-11-04 Karsten TEMME Modified bacterial strains for improved fixation of nitrogen
US20230235352A1 (en) 2020-07-14 2023-07-27 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
CN116096903A (zh) 2020-08-10 2023-05-09 先锋国际良种公司 植物调节元件及其使用方法
WO2022125639A1 (en) 2020-12-08 2022-06-16 Monsanto Technology Llc Modified plant-associated bacteria and methods of their use
US11825850B2 (en) 2020-12-21 2023-11-28 Monsanto Technology Llc Insect inhibitory proteins
UY39585A (es) 2020-12-23 2022-07-29 Monsanto Technology Llc Proteínas que exhiben actividad inhibidora de insectos frente a plagas con importancia agrícola de plantas de cultivo y semillas
WO2022146874A1 (en) 2020-12-31 2022-07-07 Monsanto Technology Llc Novel insect inhibitory proteins
TW202305130A (zh) 2021-03-26 2023-02-01 美商旗艦先鋒創新有限責任（Ｖｉｉ）公司 原核系統中環狀多核糖核苷酸之產生
TW202305129A (zh) 2021-03-26 2023-02-01 美商旗艦先鋒創新有限責任（Ｖｉｉ）公司 用於產生環狀多核糖核苷酸之組成物及方法
US20240181079A1 (en) 2021-03-26 2024-06-06 Flagship Pioneering Innovations Vii, Llc Production of circular polyribonucleotides in a eukaryotic system
CN118302038A (zh) 2021-07-02 2024-07-05 皮沃特生物股份有限公司 用于改良固氮的基因工程化细菌菌株
WO2023077118A1 (en) 2021-11-01 2023-05-04 Flagship Pioneering Innovations Vii, Llc Polynucleotides for modifying organisms
WO2023141540A2 (en) 2022-01-20 2023-07-27 Flagship Pioneering Innovations Vii, Llc Polynucleotides for modifying organisms
TW202345696A (zh) 2022-05-18 2023-12-01 美商科迪華農業科技有限責任公司 具有殺有害生物效用之組成物及與其相關的方法
WO2024052856A1 (en) 2022-09-09 2024-03-14 Friedrich Alexander Universität Erlangen-Nürnberg Plant regulatory elements and uses thereof
WO2024137446A1 (en) 2022-12-19 2024-06-27 BASF Agricultural Solutions Seed US LLC Methods of identifying and evaluating genes for insect control
WO2024137438A2 (en) 2022-12-19 2024-06-27 BASF Agricultural Solutions Seed US LLC Insect toxin genes and methods for their use
WO2024137445A1 (en) 2022-12-20 2024-06-27 BASF Agricultural Solutions Seed US LLC Methods of identifying and evaluating genes for insect control

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US632010A (en) * 1899-06-23 1899-08-29 Henry Emmett Gamble Steam-engine.
JPH0714349B2 (ja) * 1983-01-17 1995-02-22 モンサント カンパニ− 植物細胞での発現に適したキメラ遺伝子
US5380831A (en) * 1986-04-04 1995-01-10 Mycogen Plant Science, Inc. Synthetic insecticidal crystal protein gene
BR8600161A (pt) * 1985-01-18 1986-09-23 Plant Genetic Systems Nv Gene quimerico,vetores de plasmidio hibrido,intermediario,processo para controlar insetos em agricultura ou horticultura,composicao inseticida,processo para transformar celulas de plantas para expressar uma toxina de polipeptideo produzida por bacillus thuringiensis,planta,semente de planta,cultura de celulas e plasmidio
US4771131A (en) * 1985-08-16 1988-09-13 Mycogen Corporation Cloning and expression of Bacillus thuringiensis toxin gene encoding a protein toxic to beetles of the order Coleoptera
CA1341092C (en) * 1985-12-12 2000-09-05 David L. Edwards Process for altering the host range of bacillus thuringiensis toxins, and novel toxins produced thereby
TR27832A (tr) 1987-04-29 1995-08-31 Monsanto Co Zararli ucucu hasarata mukavim bitkiler.
DK240088A (da) * 1987-05-05 1988-11-06 Sandoz Ag Fremgangsmaade til transformation af et plantecellematerale
ES2121803T3 (es) * 1987-05-20 1998-12-16 Novartis Ag Plantas de zea mays y plantas transgenicas de zea mays generadas a partir de protoplastos o celulas derivadas de protoplastos.
US5128130A (en) * 1988-01-22 1992-07-07 Mycogen Corporation Hybrid Bacillus thuringiensis gene, plasmid and transformed Pseudomonas fluorescens
US5055294A (en) * 1988-03-03 1991-10-08 Mycogen Corporation Chimeric bacillus thuringiensis crystal protein gene comprising hd-73 and berliner 1715 toxin genes, transformed and expressed in pseudomonas fluorescens
ES2077589T3 (es) * 1988-04-25 1995-12-01 Monsanto Co Plantas de lechuga resistentes a insectos.
NZ230375A (en) * 1988-09-09 1991-07-26 Lubrizol Genetics Inc Synthetic gene encoding b. thuringiensis insecticidal protein
BR9007159A (pt) * 1989-02-24 1991-12-10 Monsanto Co Genes sinteticos de plantas e processo para a preparacao dos mesmos
US5143905A (en) * 1990-05-03 1992-09-01 The Regents Of The University Of California Method and means for extending the host range of insecticidal proteins
US5384253A (en) * 1990-12-28 1995-01-24 Dekalb Genetics Corporation Genetic transformation of maize cells by electroporation of cells pretreated with pectin degrading enzymes
UA48104C2 (uk) 1991-10-04 2002-08-15 Новартіс Аг Фрагмент днк, який містить послідовність,що кодує інсектицидний протеїн, оптимізовану для кукурудзи,фрагмент днк, який забезпечує направлену бажану для серцевини стебла експресію зв'язаного з нею структурного гена в рослині, фрагмент днк, який забезпечує специфічну для пилку експресію зв`язаного з нею структурного гена в рослині, рекомбінантна молекула днк, спосіб одержання оптимізованої для кукурудзи кодуючої послідовності інсектицидного протеїну, спосіб захисту рослин кукурудзи щонайменше від однієї комахи-шкідника
US5449681A (en) * 1992-12-30 1995-09-12 Eli Lilly And Company Use of disulfonyl methanes for the control of parasites
US5441884A (en) * 1993-07-08 1995-08-15 Ecogen Inc. Bacillus thuringiensis transposon TN5401
US5843744A (en) * 1993-07-08 1998-12-01 Ecogen Inc. Bacillus thuringiensis Tn5401 proteins
GB9318207D0 (en) 1993-09-02 1993-10-20 Sandoz Ltd Improvements in or relating to organic compounds
US5593881A (en) * 1994-05-06 1997-01-14 Mycogen Corporation Bacillus thuringiensis delta-endotoxin
US5527883A (en) * 1994-05-06 1996-06-18 Mycogen Corporation Delta-endotoxin expression in pseudomonas fluorescens
US5508264A (en) * 1994-12-06 1996-04-16 Mycogen Corporation Pesticidal compositions
US5804180A (en) * 1996-07-17 1998-09-08 Ecogen, Inc. Bacillus thuringiensis strains showing improved production of certain lepidopteran-toxic crystal proteins
US6713063B1 (en) * 1996-11-20 2004-03-30 Monsanto Technology, Llc Broad-spectrum δ-endotoxins
US6017534A (en) * 1996-11-20 2000-01-25 Ecogen, Inc. Hybrid Bacillus thuringiensis δ-endotoxins with novel broad-spectrum insecticidal activity
BR9713373A (pt) 1996-11-20 2001-06-19 Ecogen Inc Delta-endotoxinas de amplo espectro

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