MX2018003044A - Variantes de hppd y metodos de uso. - Google Patents

Variantes de hppd y metodos de uso.

Info

Publication number
MX2018003044A
MX2018003044A MX2018003044A MX2018003044A MX2018003044A MX 2018003044 A MX2018003044 A MX 2018003044A MX 2018003044 A MX2018003044 A MX 2018003044A MX 2018003044 A MX2018003044 A MX 2018003044A MX 2018003044 A MX2018003044 A MX 2018003044A
Authority
MX
Mexico
Prior art keywords
hppd
inhibitors
inhibitor herbicides
polypeptides
mutant
Prior art date
Application number
MX2018003044A
Other languages
English (en)
Inventor
Lange Gudrun
Laber Bernd
Strerath Michael
Dubald Manuel
Tebbe Jan
LINKA Marc
Poree Fabien
Coco Wayne
Weber Ernst
Pawlowski Nikolaus
Geske Sandra
Balven-Ross Heike
Wobst Mina
Thies Christina
Original Assignee
Bayer Cropscience Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Cropscience Ag filed Critical Bayer Cropscience Ag
Publication of MX2018003044A publication Critical patent/MX2018003044A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8274—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for herbicide resistance
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0069—Oxidoreductases (1.) acting on single donors with incorporation of molecular oxygen, i.e. oxygenases (1.13)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y113/00—Oxidoreductases acting on single donors with incorporation of molecular oxygen (oxygenases) (1.13)
    • C12Y113/11—Oxidoreductases acting on single donors with incorporation of molecular oxygen (oxygenases) (1.13) with incorporation of two atoms of oxygen (1.13.11)
    • C12Y113/11027—4-Hydroxyphenylpyruvate dioxygenase (1.13.11.27)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Catching Or Destruction (AREA)

Abstract

En la presente invención, se describen polipéptidos de HPPD y las plantas que los contienen que muestran una tolerancia plena contra uno o más herbicidas inhibidores de HPPD que pertenecen a varias clases químicas. Se diseñan un conjunto de polipéptidos de HPPD mutante que tienen nula o solamente una afinidad significativamente reducida a los herbicidas inhibidores de HPPD y, al mismo tiempo, la velocidad de disociación de los inhibidores de HPPD del polipéptido de HPPD mutante aumenta en tal medida que los inhibidores de HPPD ya no actúan como inhibidores de unión lenta o de unión lenta y fuerte, sino que en lugar de esto, se han convertido en inhibidores completamente reversibles. En particular, se proporcionan polinucleótidos aislados que codifican polipéptidos de HPPD mutante que otorgan tolerancia a los herbicidas inhibidores de HPPD que pertenecen a distintas clases químicas. Adicionalmente, se comprenden secuencias de aminoácidos que corresponden a los polinucleótidos.
MX2018003044A 2015-09-11 2016-09-08 Variantes de hppd y metodos de uso. MX2018003044A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15184866 2015-09-11
PCT/EP2016/071159 WO2017042259A1 (en) 2015-09-11 2016-09-08 Hppd variants and methods of use

Publications (1)

Publication Number Publication Date
MX2018003044A true MX2018003044A (es) 2018-04-11

Family

ID=54140322

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018003044A MX2018003044A (es) 2015-09-11 2016-09-08 Variantes de hppd y metodos de uso.

Country Status (17)

Country Link
US (1) US10597674B2 (es)
EP (1) EP3347475B1 (es)
JP (1) JP6873979B2 (es)
KR (1) KR20180043838A (es)
CN (1) CN108884470B (es)
AR (1) AR105984A1 (es)
AU (1) AU2016319093B2 (es)
BR (1) BR112018004779A8 (es)
CA (1) CA2998036A1 (es)
EA (1) EA201890696A1 (es)
ES (1) ES2933673T3 (es)
HK (1) HK1258349A1 (es)
MX (1) MX2018003044A (es)
UA (1) UA126550C2 (es)
UY (1) UY36898A (es)
WO (1) WO2017042259A1 (es)
ZA (1) ZA201802329B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11180770B2 (en) * 2017-03-07 2021-11-23 BASF Agricultural Solutions Seed US LLC HPPD variants and methods of use
US11708565B2 (en) * 2017-03-07 2023-07-25 BASF Agricultural Solutions Seesi US LLC HPPD variants and methods of use
US11371056B2 (en) * 2017-03-07 2022-06-28 BASF Agricultural Solutions Seed US LLC HPPD variants and methods of use
CN107794263B (zh) * 2017-09-30 2019-10-11 河北大学 一种提高黑色素产率的基因及其应用
WO2019227036A1 (en) * 2018-05-25 2019-11-28 BASF Agricultural Solutions Seed US LLC Plants containing elite event ee-gm5 and methods and kits for identifying such event in biological samples, and treatment thereof
MX2020012704A (es) * 2018-05-25 2021-04-13 BASF Agricultural Solutions Seed US LLC Plantas que contienen el evento elite ee-gm4, y metodos y kits para identificar dicho evento en muestras biologicas, y tratamiento de estas.
CN116064430B (zh) * 2021-09-14 2023-08-11 山东舜丰生物科技有限公司 突变的hppd多肽及其应用
WO2023114849A2 (en) * 2021-12-14 2023-06-22 Colorado State University Research Foundation Cyp72a219 genes conferring herbicide tolerance
WO2024138014A1 (en) * 2022-12-22 2024-06-27 Syngenta Crop Protection Ag Herbicidal compositions
WO2024160989A1 (en) 2023-02-03 2024-08-08 Syngenta Crop Protection Ag Herbicide resistant plants

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EP3347475A1 (en) 2018-07-18
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