JP2000502324A - 異種抗体を産生することができるトランスジェニック非ヒト動物 - Google Patents
異種抗体を産生することができるトランスジェニック非ヒト動物Info
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- JP2000502324A JP2000502324A JP9515285A JP51528597A JP2000502324A JP 2000502324 A JP2000502324 A JP 2000502324A JP 9515285 A JP9515285 A JP 9515285A JP 51528597 A JP51528597 A JP 51528597A JP 2000502324 A JP2000502324 A JP 2000502324A
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Applications Claiming Priority (3)
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| US08/544,404 | 1995-10-10 | ||
| US08/544,404 US5770429A (en) | 1990-08-29 | 1995-10-10 | Transgenic non-human animals capable of producing heterologous antibodies |
| PCT/US1996/016433 WO1997013852A1 (en) | 1995-10-10 | 1996-10-10 | Transgenic non-human animals capable of producing heterologous antibodies |
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| JP2007198202A Division JP2007332152A (ja) | 1995-10-10 | 2007-07-30 | 異種抗体を産生することができるトランスジェニック非ヒト動物 |
| JP2008121728A Division JP4897736B2 (ja) | 1995-10-10 | 2008-05-07 | 異種抗体を産生することができるトランスジェニック非ヒト動物 |
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| JP2008113242A Withdrawn JP2008189691A (ja) | 1995-10-10 | 2008-04-23 | 異種抗体を産生することができるトランスジェニック非ヒト動物 |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006523433A (ja) * | 2002-11-15 | 2006-10-19 | ゲンマブ エー/エス | Cd25に対するヒトモノクローナル抗体 |
| JP2007332152A (ja) * | 1995-10-10 | 2007-12-27 | Genpharm Internatl Inc | 異種抗体を産生することができるトランスジェニック非ヒト動物 |
| JP2013090631A (ja) * | 2001-02-16 | 2013-05-16 | Regeneron Pharmaceuticals Inc | 真核生物細胞を改変する方法 |
| JP2017104125A (ja) * | 2000-10-31 | 2017-06-15 | リジェネロン・ファーマシューティカルズ・インコーポレイテッドRegeneron Pharmaceuticals, Inc. | 真核生物細胞を改変する方法 |
| JP2019030307A (ja) * | 2008-08-11 | 2019-02-28 | イー・アール・スクイブ・アンド・サンズ・リミテッド・ライアビリティ・カンパニーE.R. Squibb & Sons, L.L.C. | リンパ球活性化遺伝子−3(lag−3)へ結合するヒト抗体およびその使用 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US7084260B1 (en) * | 1996-10-10 | 2006-08-01 | Genpharm International, Inc. | High affinity human antibodies and human antibodies against human antigens |
| US6300129B1 (en) * | 1990-08-29 | 2001-10-09 | Genpharm International | Transgenic non-human animals for producing heterologous antibodies |
| US7041871B1 (en) | 1995-10-10 | 2006-05-09 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US7105159B1 (en) | 1992-11-05 | 2006-09-12 | Sloan-Kettering Institute For Cancer Research | Antibodies to prostate-specific membrane antigen |
| US6090382A (en) | 1996-02-09 | 2000-07-18 | Basf Aktiengesellschaft | Human antibodies that bind human TNFα |
| DE69721548T2 (de) | 1996-02-09 | 2004-04-01 | Abbott Laboratories(Bermuda)Ltd. | HUMANE ANTIKÖRPER WELCHE AN HUMANEN TNFalpha BINDEN |
| US20050136066A1 (en) * | 1996-06-12 | 2005-06-23 | Yajun Guo | Cellular vaccines and immunotherapeutics and methods for their preparation |
| US6805869B2 (en) | 1996-06-12 | 2004-10-19 | Shanghai Cp Guojian Pharmaceutical Co., Ltd. | Cellular vaccines and immunotherapeutics and methods for their preparation |
| US7910096B2 (en) | 1996-11-15 | 2011-03-22 | Trustees Of Tufts College | Human neutralizing antibodies against hemolytic uremic syndrome |
| US7049101B1 (en) * | 1997-08-06 | 2006-05-23 | Diversa Corporation | Enzymes having high temperature polymerase activity and methods of use thereof |
| US7964192B1 (en) | 1997-12-02 | 2011-06-21 | Janssen Alzheimer Immunotherapy | Prevention and treatment of amyloidgenic disease |
| US7179892B2 (en) | 2000-12-06 | 2007-02-20 | Neuralab Limited | Humanized antibodies that recognize beta amyloid peptide |
| EP1520588B1 (en) | 1998-07-13 | 2014-12-24 | Board Of Regents, The University Of Texas System | Uses of antibodies to aminophospholipids for cancer treatment |
| BR9911882A (pt) | 1998-07-13 | 2005-02-15 | Univ Texas | Processo de tratamento de câncer empregando anticorpos a aminofosfolipìdios |
| US7109003B2 (en) | 1998-12-23 | 2006-09-19 | Abgenix, Inc. | Methods for expressing and recovering human monoclonal antibodies to CTLA-4 |
| EE05627B1 (et) * | 1998-12-23 | 2013-02-15 | Pfizer Inc. | CTLA-4 vastased inimese monoklonaalsed antikehad |
| WO2000037504A2 (en) | 1998-12-23 | 2000-06-29 | Pfizer Inc. | Human monoclonal antibodies to ctla-4 |
| US6914128B1 (en) | 1999-03-25 | 2005-07-05 | Abbott Gmbh & Co. Kg | Human antibodies that bind human IL-12 and methods for producing |
| UA81216C2 (en) | 1999-06-01 | 2007-12-25 | Prevention and treatment of amyloid disease | |
| US6833268B1 (en) | 1999-06-10 | 2004-12-21 | Abgenix, Inc. | Transgenic animals for producing specific isotypes of human antibodies via non-cognate switch regions |
| EP1212422B1 (en) | 1999-08-24 | 2007-02-21 | Medarex, Inc. | Human ctla-4 antibodies and their uses |
| US7605238B2 (en) | 1999-08-24 | 2009-10-20 | Medarex, Inc. | Human CTLA-4 antibodies and their uses |
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- 1996-10-10 AU AU11149/97A patent/AU729290B2/en not_active Expired
- 1996-10-10 WO PCT/US1996/016433 patent/WO1997013852A1/en not_active Ceased
- 1996-10-10 CN CN201210119281.3A patent/CN102827283B/zh not_active Expired - Lifetime
- 1996-10-10 CA CA2232813A patent/CA2232813C/en not_active Expired - Lifetime
- 1996-10-10 CN CN2006101318430A patent/CN101002549B/zh not_active Expired - Lifetime
- 1996-10-10 EP EP07075027A patent/EP1813672A3/en not_active Withdrawn
- 1996-10-10 JP JP9515285A patent/JP2000502324A/ja not_active Withdrawn
- 1996-10-10 IL IL12404396A patent/IL124043A/xx not_active IP Right Cessation
- 1996-10-10 CN CNB961975547A patent/CN1286975C/zh not_active Expired - Lifetime
- 1996-10-10 EP EP96941938A patent/EP0854917B1/en not_active Expired - Lifetime
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009201524A (ja) * | 1995-10-10 | 2009-09-10 | Genpharm Internatl Inc | 異種抗体を産生することができるトランスジェニック非ヒト動物 |
| JP2007332152A (ja) * | 1995-10-10 | 2007-12-27 | Genpharm Internatl Inc | 異種抗体を産生することができるトランスジェニック非ヒト動物 |
| JP2008239630A (ja) * | 1995-10-10 | 2008-10-09 | Genpharm Internatl Inc | 異種抗体を産生することができるトランスジェニック非ヒト動物 |
| JP2017104125A (ja) * | 2000-10-31 | 2017-06-15 | リジェネロン・ファーマシューティカルズ・インコーポレイテッドRegeneron Pharmaceuticals, Inc. | 真核生物細胞を改変する方法 |
| JP2017123855A (ja) * | 2000-10-31 | 2017-07-20 | リジェネロン・ファーマシューティカルズ・インコーポレイテッドRegeneron Pharmaceuticals, Inc. | 真核生物細胞を改変する方法 |
| JP2013090631A (ja) * | 2001-02-16 | 2013-05-16 | Regeneron Pharmaceuticals Inc | 真核生物細胞を改変する方法 |
| JP2016189796A (ja) * | 2001-02-16 | 2016-11-10 | リジェネロン・ファーマシューティカルズ・インコーポレイテッドRegeneron Pharmaceuticals, Inc. | 真核生物細胞を改変する方法 |
| JP2018108115A (ja) * | 2001-02-16 | 2018-07-12 | リジェネロン・ファーマシューティカルズ・インコーポレイテッドRegeneron Pharmaceuticals, Inc. | 真核生物細胞を改変する方法 |
| US8182812B2 (en) | 2002-11-15 | 2012-05-22 | Genmab A/S | Human monoclonal antibodies against CD25 |
| US8961968B2 (en) | 2002-11-15 | 2015-02-24 | Genmab A/S | Human monoclonal antibodies against CD25 |
| US9598493B2 (en) | 2002-11-15 | 2017-03-21 | Genmab A/S | Human monoclonal antibodies against CD25 |
| JP2006523433A (ja) * | 2002-11-15 | 2006-10-19 | ゲンマブ エー/エス | Cd25に対するヒトモノクローナル抗体 |
| US10703818B2 (en) | 2002-11-15 | 2020-07-07 | Genmab A/S | Human monoclonal antibodies against CD25 |
| JP2019030307A (ja) * | 2008-08-11 | 2019-02-28 | イー・アール・スクイブ・アンド・サンズ・リミテッド・ライアビリティ・カンパニーE.R. Squibb & Sons, L.L.C. | リンパ球活性化遺伝子−3(lag−3)へ結合するヒト抗体およびその使用 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2186888A1 (en) | 2010-05-19 |
| JP2008239630A (ja) | 2008-10-09 |
| JP2011236257A (ja) | 2011-11-24 |
| JP2007332152A (ja) | 2007-12-27 |
| CN1199422A (zh) | 1998-11-18 |
| EP0854917A4 (en) | 2002-07-24 |
| CN102827283A (zh) | 2012-12-19 |
| EP0854917A1 (en) | 1998-07-29 |
| ES2345580T3 (es) | 2010-09-27 |
| ATE466936T1 (de) | 2010-05-15 |
| EP1813672A3 (en) | 2008-05-28 |
| CA2232813C (en) | 2013-12-17 |
| JP4897736B2 (ja) | 2012-03-14 |
| US5770429A (en) | 1998-06-23 |
| CN101002549B (zh) | 2012-05-30 |
| DK0854917T3 (da) | 2010-08-30 |
| JP2008189691A (ja) | 2008-08-21 |
| CN102827283B (zh) | 2014-11-12 |
| EP0854917B1 (en) | 2010-05-05 |
| AU1114997A (en) | 1997-04-30 |
| JP2009201524A (ja) | 2009-09-10 |
| AU729290B2 (en) | 2001-02-01 |
| DE69638184D1 (de) | 2010-06-17 |
| CN1286975C (zh) | 2006-11-29 |
| IL168028A (en) | 2011-11-30 |
| CN101002549A (zh) | 2007-07-25 |
| IL124043A (en) | 2005-08-31 |
| EP1813672A2 (en) | 2007-08-01 |
| NZ324076A (en) | 2000-05-26 |
| WO1997013852A1 (en) | 1997-04-17 |
| CA2232813A1 (en) | 1997-04-17 |
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