BR112022024629A2 - Construtos anti-cd93 e seus usos - Google Patents

Construtos anti-cd93 e seus usos

Info

Publication number
BR112022024629A2
BR112022024629A2 BR112022024629A BR112022024629A BR112022024629A2 BR 112022024629 A2 BR112022024629 A2 BR 112022024629A2 BR 112022024629 A BR112022024629 A BR 112022024629A BR 112022024629 A BR112022024629 A BR 112022024629A BR 112022024629 A2 BR112022024629 A2 BR 112022024629A2
Authority
BR
Brazil
Prior art keywords
constructs
construct
vectors
methods
nucleic acid
Prior art date
Application number
BR112022024629A
Other languages
English (en)
Inventor
Chen Zirong
Guerrette Roxann
Jones Gregory
Komaba Shigeru
Li Jian
Norton Angela
Wu Lihua
Xia Zhinan
Original Assignee
Dynamicure Biotechnology Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dynamicure Biotechnology Llc filed Critical Dynamicure Biotechnology Llc
Publication of BR112022024629A2 publication Critical patent/BR112022024629A2/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

CONSTRUTOS ANTI-CD93 E USOS DOS MESMOS. A presente invenção refere-se a construtos anti-CD93 que se ligam a CD93 (etileno glicol, anticorpos anti-CD93), moléculas de ácido nucleico codificando uma sequência de aminoácidos dos vetores anti-CD93, compreendendo as moléculas de ácido nucleico, células hospedeiras contendo os vetores, métodos de preparação da construto anti-CD93, composições farmacêuticas contendo a construto anti-CD93 e métodos de utilização da construto ou composições anti-CD93.
BR112022024629A 2020-06-02 2021-06-02 Construtos anti-cd93 e seus usos BR112022024629A2 (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US202063033755P 2020-06-02 2020-06-02
US202063058359P 2020-07-29 2020-07-29
US202063084474P 2020-09-28 2020-09-28
PCT/US2021/035542 WO2021247769A1 (en) 2020-06-02 2021-06-02 Anti-cd93 constructs and uses thereof

Publications (1)

Publication Number Publication Date
BR112022024629A2 true BR112022024629A2 (pt) 2023-02-23

Family

ID=76695831

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112022024629A BR112022024629A2 (pt) 2020-06-02 2021-06-02 Construtos anti-cd93 e seus usos

Country Status (12)

Country Link
US (1) US20230235075A1 (pt)
EP (1) EP4157462A1 (pt)
JP (1) JP2023529842A (pt)
KR (1) KR20230037532A (pt)
AU (1) AU2021283345A1 (pt)
BR (1) BR112022024629A2 (pt)
CA (1) CA3185858A1 (pt)
CO (1) CO2022019183A2 (pt)
IL (1) IL298735A (pt)
MX (1) MX2022015376A (pt)
TW (1) TW202210515A (pt)
WO (1) WO2021247769A1 (pt)

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Also Published As

Publication number Publication date
WO2021247769A1 (en) 2021-12-09
KR20230037532A (ko) 2023-03-16
CO2022019183A2 (es) 2023-05-19
US20230235075A1 (en) 2023-07-27
CA3185858A1 (en) 2021-12-09
JP2023529842A (ja) 2023-07-12
IL298735A (en) 2023-02-01
AU2021283345A1 (en) 2023-02-02
MX2022015376A (es) 2023-04-14
TW202210515A (zh) 2022-03-16
EP4157462A1 (en) 2023-04-05

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