DK0854917T3 - Transgene ikke-humane dyr, som kan producere heterologe antistoffer - Google Patents

Transgene ikke-humane dyr, som kan producere heterologe antistoffer

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Publication number
DK0854917T3
DK0854917T3 DK96941938.1T DK96941938T DK0854917T3 DK 0854917 T3 DK0854917 T3 DK 0854917T3 DK 96941938 T DK96941938 T DK 96941938T DK 0854917 T3 DK0854917 T3 DK 0854917T3
Authority
DK
Denmark
Prior art keywords
transgenic non
human animals
animals capable
heterologous antibodies
producing heterologous
Prior art date
Application number
DK96941938.1T
Other languages
Danish (da)
English (en)
Inventor
Nils Lonberg
Robert M Kay
Diane M Fishwild
Original Assignee
Genpharm Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24172033&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0854917(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genpharm Int filed Critical Genpharm Int
Application granted granted Critical
Publication of DK0854917T3 publication Critical patent/DK0854917T3/da

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    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
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    • A01K67/0276—Knock-out vertebrates
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    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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    • C07K16/4241—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig
    • C07K16/4258—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig against anti-receptor Ig
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    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
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    • C12N5/10—Cells modified by introduction of foreign genetic material
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    • C12N5/16—Animal cells
    • C12N5/163—Animal cells one of the fusion partners being a B or a T lymphocyte
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DK96941938.1T 1995-10-10 1996-10-10 Transgene ikke-humane dyr, som kan producere heterologe antistoffer DK0854917T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/544,404 US5770429A (en) 1990-08-29 1995-10-10 Transgenic non-human animals capable of producing heterologous antibodies
PCT/US1996/016433 WO1997013852A1 (en) 1995-10-10 1996-10-10 Transgenic non-human animals capable of producing heterologous antibodies

Publications (1)

Publication Number Publication Date
DK0854917T3 true DK0854917T3 (da) 2010-08-30

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Application Number Title Priority Date Filing Date
DK96941938.1T DK0854917T3 (da) 1995-10-10 1996-10-10 Transgene ikke-humane dyr, som kan producere heterologe antistoffer

Country Status (13)

Country Link
US (1) US5770429A (enExample)
EP (3) EP2186888A1 (enExample)
JP (6) JP2000502324A (enExample)
CN (3) CN102827283B (enExample)
AT (1) ATE466936T1 (enExample)
AU (1) AU729290B2 (enExample)
CA (1) CA2232813C (enExample)
DE (1) DE69638184D1 (enExample)
DK (1) DK0854917T3 (enExample)
ES (1) ES2345580T3 (enExample)
IL (2) IL124043A (enExample)
NZ (1) NZ324076A (enExample)
WO (1) WO1997013852A1 (enExample)

Families Citing this family (1639)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7041871B1 (en) * 1995-10-10 2006-05-09 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
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