MX357708B - Composicion y metodo para el diagnostico y tratamiento de trastornos relacionados con hierro. - Google Patents

Composicion y metodo para el diagnostico y tratamiento de trastornos relacionados con hierro.

Info

Publication number
MX357708B
MX357708B MX2014007177A MX2014007177A MX357708B MX 357708 B MX357708 B MX 357708B MX 2014007177 A MX2014007177 A MX 2014007177A MX 2014007177 A MX2014007177 A MX 2014007177A MX 357708 B MX357708 B MX 357708B
Authority
MX
Mexico
Prior art keywords
iron
related disorders
diagnosis
treatment
composition
Prior art date
Application number
MX2014007177A
Other languages
English (en)
Other versions
MX2014007177A (es
Inventor
Mueller Bernhard
Popp Andreas
M Perez Jennifer
Original Assignee
Abbvie Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbvie Deutschland filed Critical Abbvie Deutschland
Publication of MX2014007177A publication Critical patent/MX2014007177A/es
Publication of MX357708B publication Critical patent/MX357708B/es

Links

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención se refiere a métodos para utilizar los anticuerpos que se unen a RGMc para tratar y diagnosticar trastornos relacionados con hierro.
MX2014007177A 2011-12-14 2012-12-13 Composicion y metodo para el diagnostico y tratamiento de trastornos relacionados con hierro. MX357708B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161570715P 2011-12-14 2011-12-14
PCT/US2012/069586 WO2013090635A2 (en) 2011-12-14 2012-12-13 Composition and method for the diagnosis and treatment of iron-related disorders

Publications (2)

Publication Number Publication Date
MX2014007177A MX2014007177A (es) 2014-10-17
MX357708B true MX357708B (es) 2018-07-20

Family

ID=47436267

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2014007177A MX357708B (es) 2011-12-14 2012-12-13 Composicion y metodo para el diagnostico y tratamiento de trastornos relacionados con hierro.
MX2018008882A MX2018008882A (es) 2011-12-14 2014-06-13 Composicion y metodo para el diagnostico y tratamiento de trastornos relacionados con hierro.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2018008882A MX2018008882A (es) 2011-12-14 2014-06-13 Composicion y metodo para el diagnostico y tratamiento de trastornos relacionados con hierro.

Country Status (8)

Country Link
US (5) US10118958B2 (es)
EP (2) EP2791173B1 (es)
JP (6) JP6342812B2 (es)
CN (2) CN104144947B (es)
AU (5) AU2012352168C1 (es)
CA (2) CA2855840C (es)
MX (2) MX357708B (es)
WO (1) WO2013090635A2 (es)

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JP2022549506A (ja) * 2019-09-27 2022-11-25 ディスク・メディシン・インコーポレイテッド 骨髄線維症および関連状態を処置するための方法
JP7583401B2 (ja) 2020-04-13 2024-11-14 国立大学法人大阪大学 血液分析装置
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IL297494A (en) * 2020-05-13 2022-12-01 Disc Medicine Inc Anti-hemoglobin (hjv) antibodies for the treatment of anemia of chronic disease
KR20230012539A (ko) * 2020-05-13 2023-01-26 디스크 메디슨, 인크. 골수섬유증을 치료하기 위한 항-헤모주벨린 (hjv) 항체
WO2022098812A1 (en) 2020-11-04 2022-05-12 Keros Therapeutics, Inc. Methods of treating iron overload
AU2022394462A1 (en) 2021-11-17 2024-05-02 AbbVie Deutschland GmbH & Co. KG Methods for treating anemia of kidney disease
WO2025182763A1 (ja) * 2024-02-29 2025-09-04 富士レビオ株式会社 検出方法、検出装置、並びに、これらに用いる処理液及びキット

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