SG11201505713YA - B cell lineage based immunogen design with humanized animals - Google Patents
B cell lineage based immunogen design with humanized animalsInfo
- Publication number
- SG11201505713YA SG11201505713YA SG11201505713YA SG11201505713YA SG11201505713YA SG 11201505713Y A SG11201505713Y A SG 11201505713YA SG 11201505713Y A SG11201505713Y A SG 11201505713YA SG 11201505713Y A SG11201505713Y A SG 11201505713YA SG 11201505713Y A SG11201505713Y A SG 11201505713YA
- Authority
- SG
- Singapore
- Prior art keywords
- cell lineage
- humanized animals
- immunogen design
- based immunogen
- lineage based
- Prior art date
Links
- 241001465754 Metazoa Species 0.000 title 1
- 210000003719 b-lymphocyte Anatomy 0.000 title 1
- 230000002163 immunogen Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1036—Retroviridae, e.g. leukemia viruses
- C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
- A01K67/0278—Knock-in vertebrates, e.g. humanised vertebrates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1018—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/07—Animals genetically altered by homologous recombination
- A01K2217/072—Animals genetically altered by homologous recombination maintaining or altering function, i.e. knock in
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/105—Murine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/01—Animal expressing industrially exogenous proteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Environmental Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biodiversity & Conservation Biology (AREA)
- Zoology (AREA)
- Animal Husbandry (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Biotechnology (AREA)
- Pulmonology (AREA)
- AIDS & HIV (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Communicable Diseases (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361761419P | 2013-02-06 | 2013-02-06 | |
| PCT/US2014/015133 WO2014124156A1 (en) | 2013-02-06 | 2014-02-06 | B cell lineage based immunogen design with humanized animals |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201505713YA true SG11201505713YA (en) | 2015-08-28 |
Family
ID=50150835
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201505713YA SG11201505713YA (en) | 2013-02-06 | 2014-02-06 | B cell lineage based immunogen design with humanized animals |
| SG10201706190PA SG10201706190PA (en) | 2013-02-06 | 2014-02-06 | B cell lineage based immunogen design with humanized animals |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201706190PA SG10201706190PA (en) | 2013-02-06 | 2014-02-06 | B cell lineage based immunogen design with humanized animals |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US9963501B2 (en) |
| EP (1) | EP2953452A1 (en) |
| KR (1) | KR20150115775A (en) |
| AU (2) | AU2014214863B2 (en) |
| CA (1) | CA2899740A1 (en) |
| HK (1) | HK1218866A1 (en) |
| IL (1) | IL240114B (en) |
| MX (1) | MX357061B (en) |
| RU (1) | RU2664187C2 (en) |
| SG (2) | SG11201505713YA (en) |
| WO (1) | WO2014124156A1 (en) |
| ZA (1) | ZA201505307B (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013006688A2 (en) | 2011-07-05 | 2013-01-10 | Duke University | N-terminal deleted gp120 immunogens |
| US10092638B2 (en) | 2011-10-03 | 2018-10-09 | Duke University | GP120 immunogens and methods inducing neutralizing antibodies to human immunodeficiency virus |
| MX357061B (en) | 2013-02-06 | 2018-06-25 | Regeneron Pharma | B cell lineage based immunogen design with humanized animals. |
| CA3014208A1 (en) * | 2016-02-16 | 2017-08-24 | Regeneron Pharamaceuticals, Inc. | Non-human animals having a mutant kynureninase gene |
| KR20210133234A (en) | 2019-02-18 | 2021-11-05 | 바이오사이토젠 파마슈티컬스 (베이징) 컴퍼니 리미티드 | Genetically Modified Non-Human Animals Having Humanized Immunoglobulin Locus |
| IL298632A (en) | 2020-06-02 | 2023-01-01 | Biocytogen Pharmaceuticals Beijing Co Ltd | Genetically modified non-human animals with common light chain immunoglobulin locus |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2322108A (en) | 1939-04-21 | 1943-06-15 | Molins Machine Co Ltd | Weighing apparatus |
| US5770429A (en) * | 1990-08-29 | 1998-06-23 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US6596541B2 (en) | 2000-10-31 | 2003-07-22 | Regeneron Pharmaceuticals, Inc. | Methods of modifying eukaryotic cells |
| US7105348B2 (en) | 2000-10-31 | 2006-09-12 | Regeneron Pharmaceuticals, Inc. | Methods of modifying eukaryotic cells |
| JP4720065B2 (en) | 2001-09-04 | 2011-07-13 | 日本電気株式会社 | Film outer battery and battery pack |
| US20120204278A1 (en) * | 2009-07-08 | 2012-08-09 | Kymab Limited | Animal models and therapeutic molecules |
| EP2738258B2 (en) | 2011-02-25 | 2023-02-01 | Regeneron Pharmaceuticals, Inc. | ADAM6 mice |
| US10092638B2 (en) | 2011-10-03 | 2018-10-09 | Duke University | GP120 immunogens and methods inducing neutralizing antibodies to human immunodeficiency virus |
| MX357061B (en) | 2013-02-06 | 2018-06-25 | Regeneron Pharma | B cell lineage based immunogen design with humanized animals. |
-
2014
- 2014-02-06 MX MX2015010110A patent/MX357061B/en active IP Right Grant
- 2014-02-06 EP EP14705679.0A patent/EP2953452A1/en not_active Ceased
- 2014-02-06 SG SG11201505713YA patent/SG11201505713YA/en unknown
- 2014-02-06 US US14/174,563 patent/US9963501B2/en active Active
- 2014-02-06 WO PCT/US2014/015133 patent/WO2014124156A1/en active Application Filing
- 2014-02-06 CA CA2899740A patent/CA2899740A1/en not_active Abandoned
- 2014-02-06 SG SG10201706190PA patent/SG10201706190PA/en unknown
- 2014-02-06 AU AU2014214863A patent/AU2014214863B2/en not_active Ceased
- 2014-02-06 RU RU2015137173A patent/RU2664187C2/en not_active IP Right Cessation
- 2014-02-06 KR KR1020157021156A patent/KR20150115775A/en not_active Application Discontinuation
-
2015
- 2015-07-22 ZA ZA2015/05307A patent/ZA201505307B/en unknown
- 2015-07-23 IL IL240114A patent/IL240114B/en not_active IP Right Cessation
-
2016
- 2016-06-15 HK HK16106896.4A patent/HK1218866A1/en unknown
-
2018
- 2018-03-29 US US15/940,523 patent/US10626168B2/en active Active
-
2019
- 2019-06-20 AU AU2019204329A patent/AU2019204329A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| MX2015010110A (en) | 2016-06-21 |
| EP2953452A1 (en) | 2015-12-16 |
| US20140221625A1 (en) | 2014-08-07 |
| AU2014214863B2 (en) | 2019-03-21 |
| US20180298082A1 (en) | 2018-10-18 |
| ZA201505307B (en) | 2016-07-27 |
| AU2019204329A1 (en) | 2019-07-11 |
| WO2014124156A1 (en) | 2014-08-14 |
| US9963501B2 (en) | 2018-05-08 |
| RU2664187C2 (en) | 2018-08-15 |
| IL240114B (en) | 2019-08-29 |
| IL240114A0 (en) | 2015-09-24 |
| KR20150115775A (en) | 2015-10-14 |
| HK1218866A1 (en) | 2017-03-17 |
| US10626168B2 (en) | 2020-04-21 |
| RU2015137173A (en) | 2017-03-13 |
| CA2899740A1 (en) | 2014-08-14 |
| MX357061B (en) | 2018-06-25 |
| AU2014214863A1 (en) | 2015-09-24 |
| SG10201706190PA (en) | 2017-09-28 |
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