SG10201601747XA - Anti-LRP5 Antibodies And Methods Of Use - Google Patents
Anti-LRP5 Antibodies And Methods Of UseInfo
- Publication number
- SG10201601747XA SG10201601747XA SG10201601747XA SG10201601747XA SG10201601747XA SG 10201601747X A SG10201601747X A SG 10201601747XA SG 10201601747X A SG10201601747X A SG 10201601747XA SG 10201601747X A SG10201601747X A SG 10201601747XA SG 10201601747X A SG10201601747X A SG 10201601747XA
- Authority
- SG
- Singapore
- Prior art keywords
- methods
- lrp5 antibodies
- lrp5
- antibodies
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6849—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a receptor, a cell surface antigen or a cell surface determinant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/567—Framework region [FR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/75—Agonist effect on antigen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Cell Biology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Ophthalmology & Optometry (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261588100P | 2012-01-18 | 2012-01-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10201601747XA true SG10201601747XA (en) | 2016-04-28 |
Family
ID=47604271
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201601747XA SG10201601747XA (en) | 2012-01-18 | 2013-01-18 | Anti-LRP5 Antibodies And Methods Of Use |
| SG11201404198TA SG11201404198TA (en) | 2012-01-18 | 2013-01-18 | Anti-lrp5 antibodies and methods of use |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201404198TA SG11201404198TA (en) | 2012-01-18 | 2013-01-18 | Anti-lrp5 antibodies and methods of use |
Country Status (25)
| Country | Link |
|---|---|
| US (4) | US9200072B2 (en) |
| EP (1) | EP2804629A1 (en) |
| JP (1) | JP6242813B2 (en) |
| KR (1) | KR20140116490A (en) |
| CN (1) | CN104066449B (en) |
| AR (1) | AR089752A1 (en) |
| AU (1) | AU2013209707A1 (en) |
| BR (1) | BR112014017518A2 (en) |
| CA (1) | CA2862422A1 (en) |
| CL (1) | CL2014001888A1 (en) |
| CO (1) | CO7000747A2 (en) |
| CR (1) | CR20140382A (en) |
| EA (1) | EA028202B1 (en) |
| HK (1) | HK1197187A1 (en) |
| IL (1) | IL233317A0 (en) |
| IN (1) | IN2014DN05885A (en) |
| MA (1) | MA35898B1 (en) |
| MX (1) | MX2014008157A (en) |
| NZ (1) | NZ626520A (en) |
| PE (1) | PE20141561A1 (en) |
| PH (1) | PH12014501605A1 (en) |
| SG (2) | SG10201601747XA (en) |
| TW (1) | TW201335187A (en) |
| WO (1) | WO2013109819A1 (en) |
| ZA (1) | ZA201404675B (en) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20110051245A (en) * | 2008-09-10 | 2011-05-17 | 제넨테크, 인크. | Methods for inhibiting ocular angiogenesis |
| JP5861469B2 (en) * | 2012-01-23 | 2016-02-16 | 日本電気硝子株式会社 | Glass tube clean cutting device and clean cutting method |
| US9914774B2 (en) | 2014-07-11 | 2018-03-13 | Genentech, Inc. | Notch pathway inhibition |
| AU2015314771B2 (en) | 2014-09-12 | 2021-04-01 | The Board Of Trustees Of The Leland Stanford Junior University | Wnt signaling agonist molecules |
| US11219694B2 (en) * | 2015-09-24 | 2022-01-11 | The University Of North Carolina At Chapel Hill | Methods and compositions for reducing metastases |
| CN106367517A (en) * | 2016-09-28 | 2017-02-01 | 湖北工业大学 | Low-density lipoprotein receptor-related protein 5 (LRP5) gene mutation detection reagents and application thereof |
| JP2020518675A (en) * | 2017-05-05 | 2020-06-25 | レチナール ソリューションズ エルエルシー | Norrin-induced gene expression and its use for treating diseases |
| TW201906858A (en) * | 2017-05-31 | 2019-02-16 | 德商百靈佳殷格翰國際股份有限公司 | Antagonizing polypeptides of WNT signaling in tumor cells |
| US11773171B2 (en) | 2017-12-19 | 2023-10-03 | Surrozen Operating, Inc. | WNT surrogate molecules and uses thereof |
| US11746150B2 (en) | 2017-12-19 | 2023-09-05 | Surrozen Operating, Inc. | Anti-LRP5/6 antibodies and methods of use |
| CN117946267A (en) | 2017-12-19 | 2024-04-30 | 瑟罗泽恩奥普瑞汀公司 | Anti-frizzled antibodies and methods of use |
| AU2020329092A1 (en) * | 2019-08-14 | 2022-03-31 | Antlera Therapeutics Inc. | Antibodies that bind to LRP5 proteins and methods of use |
| WO2021225954A1 (en) * | 2020-05-04 | 2021-11-11 | The Regents Of The University Of California | Inhibiting anti-enpp1 antibodies |
| CN111909935B (en) * | 2020-07-17 | 2022-11-15 | 武汉纽福斯生物科技有限公司 | Expression vector of recombinant human frizzled protein receptor 4 (FZD 4) and application thereof |
| KR102536092B1 (en) * | 2020-09-29 | 2023-05-24 | 조선대학교산학협력단 | Pharmaceutical composition for the prevention or treatment of ischemic heart disease containing an inhibitor of LRP5 expression or activity |
| WO2023250402A2 (en) * | 2022-06-22 | 2023-12-28 | Antlera Therapeutics Inc. | Tetravalent fzd and wnt co-receptor binding antibody molecules and uses thereof |
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2013
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- 2013-01-18 IN IN5885DEN2014 patent/IN2014DN05885A/en unknown
- 2013-01-18 EP EP13701352.0A patent/EP2804629A1/en not_active Withdrawn
- 2013-01-18 CA CA2862422A patent/CA2862422A1/en not_active Abandoned
- 2013-01-18 SG SG10201601747XA patent/SG10201601747XA/en unknown
- 2013-01-18 KR KR1020147022497A patent/KR20140116490A/en not_active Application Discontinuation
- 2013-01-18 CN CN201380006007.8A patent/CN104066449B/en not_active Expired - Fee Related
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- 2013-01-18 WO PCT/US2013/022045 patent/WO2013109819A1/en active Application Filing
- 2013-01-18 TW TW102102128A patent/TW201335187A/en unknown
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- 2013-01-18 US US13/744,766 patent/US9200072B2/en active Active
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- 2014-07-11 PH PH12014501605A patent/PH12014501605A1/en unknown
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- 2014-08-06 MA MA37268A patent/MA35898B1/en unknown
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- 2014-10-28 HK HK14110783.4A patent/HK1197187A1/en not_active IP Right Cessation
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2015
- 2015-10-09 US US14/879,702 patent/US9522954B2/en not_active Expired - Fee Related
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