IN2014DN05885A - - Google Patents
Info
- Publication number
- IN2014DN05885A IN2014DN05885A IN5885DEN2014A IN2014DN05885A IN 2014DN05885 A IN2014DN05885 A IN 2014DN05885A IN 5885DEN2014 A IN5885DEN2014 A IN 5885DEN2014A IN 2014DN05885 A IN2014DN05885 A IN 2014DN05885A
- Authority
- IN
- India
- Prior art keywords
- making
- methods
- same
- provides anti
- lrp5 antibodies
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6849—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a receptor, a cell surface antigen or a cell surface determinant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/567—Framework region [FR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/75—Agonist effect on antigen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Abstract
The invention provides anti LRP5 antibodies and methods of making and using the same.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261588100P | 2012-01-18 | 2012-01-18 | |
PCT/US2013/022045 WO2013109819A1 (en) | 2012-01-18 | 2013-01-18 | Anti-lrp5 antibodies and methods of use |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2014DN05885A true IN2014DN05885A (en) | 2015-06-05 |
Family
ID=47604271
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN5885DEN2014 IN2014DN05885A (en) | 2012-01-18 | 2013-01-18 |
Country Status (25)
Country | Link |
---|---|
US (4) | US9200072B2 (en) |
EP (1) | EP2804629A1 (en) |
JP (1) | JP6242813B2 (en) |
KR (1) | KR20140116490A (en) |
CN (1) | CN104066449B (en) |
AR (1) | AR089752A1 (en) |
AU (1) | AU2013209707A1 (en) |
BR (1) | BR112014017518A2 (en) |
CA (1) | CA2862422A1 (en) |
CL (1) | CL2014001888A1 (en) |
CO (1) | CO7000747A2 (en) |
CR (1) | CR20140382A (en) |
EA (1) | EA028202B1 (en) |
HK (1) | HK1197187A1 (en) |
IL (1) | IL233317A0 (en) |
IN (1) | IN2014DN05885A (en) |
MA (1) | MA35898B1 (en) |
MX (1) | MX2014008157A (en) |
NZ (1) | NZ626520A (en) |
PE (1) | PE20141561A1 (en) |
PH (1) | PH12014501605A1 (en) |
SG (2) | SG11201404198TA (en) |
TW (1) | TW201335187A (en) |
WO (1) | WO2013109819A1 (en) |
ZA (1) | ZA201404675B (en) |
Families Citing this family (15)
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EP2334702A2 (en) * | 2008-09-10 | 2011-06-22 | Genentech, Inc. | Methods for inhibiting ocular angiogenesis |
JP5861469B2 (en) * | 2012-01-23 | 2016-02-16 | 日本電気硝子株式会社 | Glass tube clean cutting device and clean cutting method |
MX2017000363A (en) | 2014-07-11 | 2017-04-27 | Genentech Inc | Notch pathway inhibition. |
US11142577B2 (en) | 2014-09-12 | 2021-10-12 | The Board Of Trustees Of The Leland Stanford Junior University | WNT signaling agonist molecules |
CN108289966A (en) * | 2015-09-24 | 2018-07-17 | 北卡罗来纳-查佩尔山大学 | Method and composition for reducing transfer |
CN106367517A (en) * | 2016-09-28 | 2017-02-01 | 湖北工业大学 | Low-density lipoprotein receptor-related protein 5 (LRP5) gene mutation detection reagents and application thereof |
WO2018204909A2 (en) * | 2017-05-05 | 2018-11-08 | Wendelin Dailey | Norrin induced expression of genes and use thereof to treat disease |
EA201992808A1 (en) | 2017-05-31 | 2020-05-14 | Бёрингер Ингельхайм Интернациональ Гмбх | POLYPEPTIDES HINDERING THE TRANSMISSION OF Wnt SIGNALS IN TUMOR CELLS |
CN111699003A (en) | 2017-12-19 | 2020-09-22 | 瑟罗泽恩公司 | anti-LRP 5/6 antibodies and methods of use |
EP3732201A4 (en) * | 2017-12-19 | 2022-04-20 | Surrozen Operating, Inc. | Wnt surrogate molecules and uses thereof |
JP2022544308A (en) * | 2019-08-14 | 2022-10-17 | モッドマブ セラピューティクス インコーポレイテッド | Antibodies that bind to LRP5 protein and methods of use |
US11834512B2 (en) | 2020-05-04 | 2023-12-05 | The Regents Of The University Of California | Inhibiting anti-ENPP1 antibodies |
CN111909935B (en) * | 2020-07-17 | 2022-11-15 | 武汉纽福斯生物科技有限公司 | Expression vector of recombinant human frizzled protein receptor 4 (FZD 4) and application thereof |
KR102536092B1 (en) * | 2020-09-29 | 2023-05-24 | 조선대학교산학협력단 | Pharmaceutical composition for the prevention or treatment of ischemic heart disease containing an inhibitor of LRP5 expression or activity |
WO2023250402A2 (en) * | 2022-06-22 | 2023-12-28 | Antlera Therapeutics Inc. | Tetravalent fzd and wnt co-receptor binding antibody molecules and uses thereof |
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-
2013
- 2013-01-18 SG SG11201404198TA patent/SG11201404198TA/en unknown
- 2013-01-18 JP JP2014553427A patent/JP6242813B2/en not_active Expired - Fee Related
- 2013-01-18 AR ARP130100154A patent/AR089752A1/en unknown
- 2013-01-18 MX MX2014008157A patent/MX2014008157A/en unknown
- 2013-01-18 CA CA2862422A patent/CA2862422A1/en not_active Abandoned
- 2013-01-18 NZ NZ626520A patent/NZ626520A/en not_active IP Right Cessation
- 2013-01-18 BR BR112014017518A patent/BR112014017518A2/en not_active IP Right Cessation
- 2013-01-18 CN CN201380006007.8A patent/CN104066449B/en not_active Expired - Fee Related
- 2013-01-18 TW TW102102128A patent/TW201335187A/en unknown
- 2013-01-18 WO PCT/US2013/022045 patent/WO2013109819A1/en active Application Filing
- 2013-01-18 SG SG10201601747XA patent/SG10201601747XA/en unknown
- 2013-01-18 EP EP13701352.0A patent/EP2804629A1/en not_active Withdrawn
- 2013-01-18 PE PE2014001118A patent/PE20141561A1/en not_active Application Discontinuation
- 2013-01-18 KR KR1020147022497A patent/KR20140116490A/en not_active Application Discontinuation
- 2013-01-18 US US13/744,766 patent/US9200072B2/en active Active
- 2013-01-18 IN IN5885DEN2014 patent/IN2014DN05885A/en unknown
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2014
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2015
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2016
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