SG11201910066QA - Antibodies recognizing tau - Google Patents

Antibodies recognizing tau

Info

Publication number
SG11201910066QA
SG11201910066QA SG11201910066QA SG11201910066QA SG 11201910066Q A SG11201910066Q A SG 11201910066QA SG 11201910066Q A SG11201910066Q A SG 11201910066QA SG 11201910066Q A SG11201910066Q A SG 11201910066QA
Authority
SG
Singapore
Prior art keywords
california
international
rule
sunnyvale
applicant
Prior art date
Application number
Inventor
Robin Barbour
Svetlana Alexander
Mark E Renz
Shuning Gai
Philip James Dolan
Tarlochan S Nijjar
Philip Payne
Original Assignee
Prothena Biosciences Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prothena Biosciences Ltd filed Critical Prothena Biosciences Ltd
Publication of SG11201910066QA publication Critical patent/SG11201910066QA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/567—Framework region [FR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Developing Agents For Electrophotography (AREA)

Abstract

WO 18/ 20 45 46 A3 (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 08 November 2018 (08.11.2018) WIPO I PCT ill~~~~~~~~ 011101010VIIIOH olo oi olo Immoomi (10) International Publication Number WO 2018/204546 A3 (51) International Patent Classification: C07K 16/18 (2006.01) A61K 39/00 (2006.01) (21) International Application Number: PCT/US2018/030739 (22) International Filing Date: 02 May 2018 (02.05.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/500,427 02 May 2017 (02.05.2017) US 62/580,408 01 November 2017 (01.11.2017) US (71) Applicant: PROTHENA BIOSCIENCES LIMITED [IE/IE]; Adelphi Plaza, Upper George's Street, Dun Laoghaire Co. Dublin, A96 T927 (IE). (71) Applicants US only): BARBOUR, Robin [US/US]; 250 Normandy Lane, Walnut Creek, California 94598 (US). ALEXANDER, Svetlana [US/US]; 913 Hollenbeck Ave., Sunnyvale, California 94087 (US). RENZ, Mark E. [US/US]; 808 Murchison Dr., Millbrae, California 94030 (US). GAI, Shuning [US/US]; 1098 Solana Drive, Moun- tain View, California 94040 (US). NIJJAR, Tarlochan S. [US/US]; 712 Ironbark Court, Orinda, California 94563 (US). DOLAN, Philip James [US/US]; 622 Edgewater Blvd. #303, Foster City, California 94404 (US). (72) Inventor; and (71) Applicant: PAYNE, Philip [US/US]; 660 Santa Paula Av- enue, Sunnyvale, California 94085 (US). (72) Inventors: BARBOUR, Robin; 250 Normandy Lane, Wal- nut Creek, California 94598 (US). ALEXANDER, Svet- lana; 913 Hollenbeck Ave., Sunnyvale, California 94087 (US). RENZ, Mark E.; 808 Murchison Dr., Millbrae, Cal- ifornia 94030 (US). GAI, Shuning; 1098 Solana Drive, Mountain View, California 94040 (US). DOLAN, Philip James; 622 Edgewater Blvd. #303, Foster City, California 94404 (US). NIJJAR, Tarlochan S.; 712 Ironbark Court, Orinda, California 94563 (US). (74) Agent: SATHER, Susan et al.; Alston & Bird LLP, 101 South Tryon Street, Bank of America Plaza, Suite 4000, Charlotte, North Carolina 28280-4000 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). (54) Title: ANTIBODIES RECOGNIZING TAU In HASA (Ns-4a (57) : The invention provides antibodies that specifically bind tau. The antibodies inhibit or delay tau-associated pathologies and associated symptomatic deterioration. [Continued on next page] WO 2018/204546 A3 MIDEDIMOMOIDIONDERIO 010 IIIIIIIIII IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIII Declarations under Rule 4.17: as to the identity of the inventor (Rule 4.17(i)) as to applicant's entitlement to apply for and be granted a patent (Rule 4.170) Published: with international search report (Art. 21(3)) before the expiration of the time limit for amending the claims and to be republished in the event of receipt of amendments (Rule 48.2(h)) with sequence listing part of description (Rule 5.2(a)) (88) Date of publication of the international search report: 13 December 2018 (13.12.2018)
SG11201910066Q 2017-05-02 2018-05-02 Antibodies recognizing tau SG11201910066QA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762500427P 2017-05-02 2017-05-02
US201762580408P 2017-11-01 2017-11-01
PCT/US2018/030739 WO2018204546A2 (en) 2017-05-02 2018-05-02 Antibodies recognizing tau

Publications (1)

Publication Number Publication Date
SG11201910066QA true SG11201910066QA (en) 2019-11-28

Family

ID=64016242

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201910066Q SG11201910066QA (en) 2017-05-02 2018-05-02 Antibodies recognizing tau

Country Status (16)

Country Link
US (1) US11958896B2 (en)
EP (1) EP3619233A4 (en)
JP (2) JP7442790B2 (en)
KR (1) KR20200030029A (en)
CN (1) CN110881274A (en)
AU (1) AU2018263935A1 (en)
BR (1) BR112019022906A2 (en)
CA (1) CA3061516A1 (en)
CO (1) CO2019013265A2 (en)
CU (1) CU24636B1 (en)
IL (1) IL270375B1 (en)
MX (1) MX2019013045A (en)
PE (1) PE20200695A1 (en)
SG (1) SG11201910066QA (en)
WO (1) WO2018204546A2 (en)
ZA (1) ZA201907819B (en)

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MX2018013386A (en) 2016-05-02 2019-02-28 Prothena Biosciences Ltd Antibodies recognizing tau.
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IL270375B1 (en) 2017-05-02 2024-08-01 Prothena Biosciences Ltd Antibodies recognizing tau
KR20200071740A (en) 2017-09-28 2020-06-19 임팩트-바이오 리미티드. Universal platform for the production of inhibitory chimeric antigen receptors (ICAR)
MA50397A (en) 2017-10-16 2020-08-26 Eisai R&D Man Co Ltd ANTI-BODY ANTI-TAU AND THEIR USES
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