SG10201913677SA - Antibody agents directed against lymphocyte activation gene-3 (lag-3) and uses thereof - Google Patents

Antibody agents directed against lymphocyte activation gene-3 (lag-3) and uses thereof

Info

Publication number
SG10201913677SA
SG10201913677SA SG10201913677SA SG10201913677SA SG10201913677SA SG 10201913677S A SG10201913677S A SG 10201913677SA SG 10201913677S A SG10201913677S A SG 10201913677SA SG 10201913677S A SG10201913677S A SG 10201913677SA SG 10201913677S A SG10201913677S A SG 10201913677SA
Authority
SG
Singapore
Prior art keywords
lag
directed against
lymphocyte activation
antibody agents
activation gene
Prior art date
Application number
SG10201913677SA
Inventor
Helen Jun
Marilyn Kehry
Peter Bowers
David King
Dmitri Bobilev
Srimoyee Ghosh
Baochuan Huang
David Jenkins
Original Assignee
Tesaro Inc
Anaptysbio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tesaro Inc, Anaptysbio Inc filed Critical Tesaro Inc
Publication of SG10201913677SA publication Critical patent/SG10201913677SA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507—Comprising a combination of two or more separate antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
    • C07K2317/41—Glycosylation, sialylation, or fucosylation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
SG10201913677SA 2017-04-27 2018-04-27 Antibody agents directed against lymphocyte activation gene-3 (lag-3) and uses thereof SG10201913677SA (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762491221P 2017-04-27 2017-04-27
US201762578215P 2017-10-27 2017-10-27
US201862614998P 2018-01-08 2018-01-08
US201862625276P 2018-02-01 2018-02-01
US201862657384P 2018-04-13 2018-04-13

Publications (1)

Publication Number Publication Date
SG10201913677SA true SG10201913677SA (en) 2020-03-30

Family

ID=63919287

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201913677SA SG10201913677SA (en) 2017-04-27 2018-04-27 Antibody agents directed against lymphocyte activation gene-3 (lag-3) and uses thereof
SG11201909395T SG11201909395TA (en) 2017-04-27 2018-04-27 Antibody agents directed against lymphocyte activation gene-3 (lag-3) and uses thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201909395T SG11201909395TA (en) 2017-04-27 2018-04-27 Antibody agents directed against lymphocyte activation gene-3 (lag-3) and uses thereof

Country Status (12)

Country Link
US (1) US20220135670A1 (en)
EP (1) EP3615572A1 (en)
JP (2) JP2020517695A (en)
KR (1) KR20200003843A (en)
CN (1) CN110799541A (en)
AU (1) AU2018256934B2 (en)
BR (1) BR112019022515A2 (en)
CA (1) CA3059468A1 (en)
MX (1) MX2019012793A (en)
SG (2) SG10201913677SA (en)
TW (1) TWI791519B (en)
WO (1) WO2018201096A1 (en)

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BR112023003427A2 (en) 2020-08-28 2023-03-21 Bristol Myers Squibb Co LAG-3 ANTAGONIST THERAPY FOR HEPATOCELLULAR CARCINOMA
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US20230364084A1 (en) * 2020-10-28 2023-11-16 The Regents Of The University Of Michigan Methods for preventing or treating conditions related to pikfyve activity
CN114621344B (en) * 2020-12-10 2022-08-30 北京东方百泰生物科技股份有限公司 Purification method of anti-LAG-3 monoclonal antibody
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WO2018201096A1 (en) 2018-11-01
SG11201909395TA (en) 2019-11-28
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