DE18203666T1 - Modifizierte polynukleotide zur herstellung von sekretierten proteinen - Google Patents

Modifizierte polynukleotide zur herstellung von sekretierten proteinen Download PDF

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Publication number
DE18203666T1
DE18203666T1 DE18203666.5T DE18203666T DE18203666T1 DE 18203666 T1 DE18203666 T1 DE 18203666T1 DE 18203666 T DE18203666 T DE 18203666T DE 18203666 T1 DE18203666 T1 DE 18203666T1
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DE
Germany
Prior art keywords
polynucleotide
composition
methylpseudouridine
interaction partner
toll
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE18203666.5T
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German (de)
English (en)
Inventor
Stephane Bancel
Tirtha Chakraborty
Antonin De Fougerolles
Sayda M. ELBASHIR
Matthias John
Atanu Roy
Susan Whoriskey
Kristy M. WOOD
Paul Hatala
Jason P. SCHRUM
Kenechi Ejebe
Jeff Lynn Ellsworth
Justin Guild
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ModernaTx Inc
Original Assignee
ModernaTx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Application filed by ModernaTx Inc filed Critical ModernaTx Inc
Publication of DE18203666T1 publication Critical patent/DE18203666T1/de
Pending legal-status Critical Current

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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DE18203666.5T 2012-04-02 2013-03-09 Modifizierte polynukleotide zur herstellung von sekretierten proteinen Pending DE18203666T1 (de)

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