ATE442041T1 - Medium für transplantat - Google Patents

Medium für transplantat

Info

Publication number
ATE442041T1
ATE442041T1 AT01957315T AT01957315T ATE442041T1 AT E442041 T1 ATE442041 T1 AT E442041T1 AT 01957315 T AT01957315 T AT 01957315T AT 01957315 T AT01957315 T AT 01957315T AT E442041 T1 ATE442041 T1 AT E442041T1
Authority
AT
Austria
Prior art keywords
media
transplant
medium
defensins
preservation
Prior art date
Application number
AT01957315T
Other languages
English (en)
Inventor
Christopher Murphy
Ted Reid
Jonathan Mcanulty
Original Assignee
Murphy Christopher J
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Murphy Christopher J filed Critical Murphy Christopher J
Application granted granted Critical
Publication of ATE442041T1 publication Critical patent/ATE442041T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A01N1/125—Freeze protecting agents, e.g. cryoprotectants or osmolarity regulators
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A01N1/124—Disinfecting agents, e.g. antimicrobials

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Reciprocating, Oscillating Or Vibrating Motors (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
AT01957315T 2000-07-28 2001-07-27 Medium für transplantat ATE442041T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US22163200P 2000-07-28 2000-07-28
US24960200P 2000-11-17 2000-11-17
US29093201P 2001-05-15 2001-05-15
PCT/US2001/023785 WO2002009738A1 (en) 2000-07-28 2001-07-27 Transplant media

Publications (1)

Publication Number Publication Date
ATE442041T1 true ATE442041T1 (de) 2009-09-15

Family

ID=27396971

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01957315T ATE442041T1 (de) 2000-07-28 2001-07-27 Medium für transplantat

Country Status (7)

Country Link
US (3) US6696238B2 (de)
EP (1) EP1305040B1 (de)
AT (1) ATE442041T1 (de)
AU (2) AU7907301A (de)
CA (1) CA2417331C (de)
DE (1) DE60139874D1 (de)
WO (1) WO2002009738A1 (de)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8409846B2 (en) 1997-09-23 2013-04-02 The United States Of America As Represented By The Department Of Veteran Affairs Compositions, methods and devices for maintaining an organ
US6809181B2 (en) 2000-06-01 2004-10-26 University Of Iowa Research Foundation Human beta-defensin-3 (HBD-3), a highly cationic beta-defensin antimicrobial peptide
AU2002227925A1 (en) * 2000-11-14 2002-05-27 Ipf Pharmaceuticals Gmbh Human beta-defensin-3
CA2451517C (en) 2001-06-22 2011-05-03 Pioneer Hi-Bred International, Inc. Defensin polynucleotides and methods of use
CU23043A1 (es) * 2001-12-20 2005-05-20 Ct Ingenieria Genetica Biotech Composicion farmaceutica que contiene factor de crecimiento epidrmico (egf) para la prevencion de la amputacion de pie diabetico.
US7354900B2 (en) 2002-05-03 2008-04-08 The Board Of Regents Of The University Of Oklahoma Treatment and inhibition of ocular infections and wounds by CAP37 and CAP37 peptides
FR2839311A1 (fr) * 2002-05-06 2003-11-07 Entomed Peptides antibacteriens, genes codant les peptides, vecteurs, organismes transformes, leurs preparations et les compositions les contenant
FR2841556B1 (fr) 2002-07-01 2007-07-20 Centre Nat Rech Scient Peptides ayant des proprietes antimicrobiennes et les compositions les contenant notamment pour la conservation des aliments
WO2004005338A1 (en) * 2002-07-08 2004-01-15 Genova, Ltd. Secreted peptides
EP1475434A1 (de) * 2003-05-09 2004-11-10 Oncoscience AG Verfahren zur Lagerung von Tumorzellen
US7776815B2 (en) 2004-02-24 2010-08-17 Wisconsin Alumni Research Foundation Use of neuropeptides for ligament healing
US7928059B2 (en) * 2004-02-24 2011-04-19 Wisconsin Alumni Research Foundation Use of neuropeptides for traumatic cartilage injury
US20070207209A1 (en) * 2004-08-27 2007-09-06 Murphy Christopher J Trophic factor combinations for nervous system treatment
US9301519B2 (en) * 2004-10-07 2016-04-05 Transmedics, Inc. Systems and methods for ex-vivo organ care
US12010987B2 (en) 2004-10-07 2024-06-18 Transmedics, Inc. Systems and methods for ex-vivo organ care and for using lactate as an indication of donor organ status
DK1768490T3 (da) 2004-10-07 2010-10-11 Transmedics Inc Systemer og fremgangsmåder til ex-vivo-organpleje
US8304181B2 (en) 2004-10-07 2012-11-06 Transmedics, Inc. Method for ex-vivo organ care and for using lactate as an indication of donor organ status
US9078428B2 (en) 2005-06-28 2015-07-14 Transmedics, Inc. Systems, methods, compositions and solutions for perfusing an organ
WO2007087570A2 (en) * 2006-01-24 2007-08-02 Northfield Laboratories, Inc. Polymerized hemoglobin media and its use in isolation and transplantation of islet cells
US8535934B2 (en) * 2006-04-19 2013-09-17 Transmedics, Inc. Systems and methods for ex vivo organ care
US9457179B2 (en) 2007-03-20 2016-10-04 Transmedics, Inc. Systems for monitoring and applying electrical currents in an organ perfusion system
US8114668B2 (en) 2007-05-14 2012-02-14 Cardiac Pacemakers, Inc. Composition for cold storage of stem cells
US7960098B2 (en) * 2007-07-12 2011-06-14 Warsaw Orthoperic, Inc. Methods and compositions for the preservation of cells and tissues
US7892724B2 (en) 2007-07-12 2011-02-22 Warsaw Orthopedic, Inc Method for enhancing the viability of mammalian cells, tissues and organs using a solution comprising two low molecular weight PEGs
US20090156488A1 (en) * 2007-09-12 2009-06-18 Zensun (Shanghai) Science & Technology Limited Use of neuregulin for organ preservation
AT505156B1 (de) * 2007-09-28 2008-11-15 Christoph Schreiber Ein neues defensin
US9462802B2 (en) 2008-01-31 2016-10-11 Transmedics, Inc. Systems and methods for ex vivo lung care
CN102089236B (zh) 2008-05-08 2013-09-18 雀巢产品技术援助有限公司 设定与饮料分配机一起使用的杯子的填充液位
US20100233669A1 (en) * 2009-03-11 2010-09-16 Cryolife, Inc. Bioburden-reducing antibiotic composition and method of use
KR101320472B1 (ko) 2010-06-16 2013-10-23 주식회사 나이벡 항균 또는 항염증 활성을 가지는 펩타이드 및 이를 유효성분으로 함유하는 약제학적 조성물
CN102295694B (zh) * 2010-06-28 2013-06-12 中国农业大学 一种抗菌多肽及其制备方法和应用
DK2704560T3 (da) 2011-04-14 2022-05-23 Transmedics Inc Organbehandlingsopløsning til maskinperfusion ex-vivo af donorlunger
EP3384938A1 (de) 2011-09-12 2018-10-10 Moderna Therapeutics, Inc. Manipulierte nukleinsäuren und verfahren zur verwendung davon
EP2834259A4 (de) 2012-04-02 2016-08-24 Moderna Therapeutics Inc Modifizierte polynukleotide
HK1206612A1 (en) 2012-04-02 2016-01-15 Moderna Therapeutics, Inc. Modified polynucleotides for the production of secreted proteins
AR089615A1 (es) 2012-12-28 2014-09-03 Consejo Nac Invest Cient Tec Peptidos antimicrobianos, composiciones que los comprenden y usos
US9707271B2 (en) 2013-03-08 2017-07-18 University Of Vermont And State Agriculture College Methods for enhancing cardiac function with the combination of CTGF and insulin or IGF-1
US9556226B2 (en) 2013-03-15 2017-01-31 The Board Of Trustees Of The University Of Arkansas Peptides with antifungal activity and methods of using the peptides
EP3086793B1 (de) 2013-12-24 2022-05-11 Virginia Commonwealth University Verwendung von oxygenierten cholesterinsulfaten (ocs) zur behandlung von nierenstörungen
CN106659151B (zh) 2014-06-02 2021-06-08 特兰斯迈迪茨公司 离体器官护理系统
ES3030496T3 (en) 2014-12-12 2025-06-30 Transmedics Inc Apparatus and method for organ perfusion
CN107949419B (zh) 2015-09-09 2021-03-05 特兰斯迈迪茨公司 离体器官护理系统用的主动脉插管
EP3374391B1 (de) 2015-11-10 2024-04-17 Visterra, Inc. Antikörpermolekülarzneimittelkonjugate die an lipopolysaccharide binden und verwendungen davon
CA3025673A1 (en) 2016-05-30 2017-12-07 Tevosol, Inc. Apparatus and method for ex vivo lung ventilation with a varying exterior pressure
WO2018081524A1 (en) * 2016-10-28 2018-05-03 Vital Therapies, Inc. Use of conditioned media from extracorporeal blood detoxifying system to supplement organ perfusion solutions
JP7303110B2 (ja) 2017-01-18 2023-07-04 ビステラ， インコーポレイテッド 抗体分子－薬物コンジュゲートおよびその使用
BR112020005121A2 (pt) * 2017-09-14 2020-09-24 Alere San Diego Inc. detecção de amplificação pela polimerase recombinase usando sonda de duplo hapteno
FR3072246B1 (fr) * 2017-10-13 2020-06-12 Biodesiv Efnium Polymere antimicrobien pour semences animales
US11969476B2 (en) 2020-04-03 2024-04-30 Visterra, Inc. Antibody molecule-drug conjugates and uses thereof
WO2023288115A1 (en) * 2021-07-15 2023-01-19 Sio2 Medical Products, Inc. Preservative composition for nucleic acids and biological samples and methods of use
US12471592B2 (en) * 2021-08-18 2025-11-18 Reelabs Private Limited Cytoprotective compositions for short-term cells storage and transportation without cryopreservation and deep freezing

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4543252A (en) 1982-01-21 1985-09-24 The Regents Of The University Of California Cationic oligopeptides having microbicidal activity
US4659692A (en) 1982-11-19 1987-04-21 The Regents Of The University Of California Cationic oligopeptides having microbicidal activity
JPS6038329A (ja) * 1983-08-11 1985-02-27 Lion Corp う蝕予防剤
US4705777A (en) 1985-02-25 1987-11-10 The Regents Of The University Of California Cationic oligopeptides having microbicidal activity
US4798824A (en) 1985-10-03 1989-01-17 Wisconsin Alumni Research Foundation Perfusate for the preservation of organs
US5410019A (en) 1987-09-24 1995-04-25 The Administrators Of The Tulane-Educational Fund Therapeutic peptides
US5470828A (en) 1987-12-24 1995-11-28 Gropep Pty. Ltd. Peptide analogs of insulin-like growth factor II
IT1219874B (it) 1988-03-18 1990-05-24 Fidia Farmaceutici Utilizzazione del fattore di crescita nervoso umano e sue composizioni farmaceutiche
US5218093A (en) 1989-03-01 1993-06-08 Allelix Biopharmaceuticals, Inc. EGF variants and pharmaceutical use thereof
US5130298A (en) 1989-05-16 1992-07-14 Ethicon, Inc. Stabilized compositions containing epidermal growth factor
IT1238348B (it) 1989-11-16 1993-07-13 Processo per la preparazione di costrutti genetici per l'espressione del fattore di crescita nervoso in cellule eucariote.
US5792831A (en) 1990-02-08 1998-08-11 Magainin Pharmaceuticals Inc. Analogues of magainin peptides containing D-amino acids
US5183805A (en) 1990-08-13 1993-02-02 Board Of Regents, The University Of Texas System Bioactive egf peptides for promotion of tissue regeneration and cancer therapy
DE69220259T2 (de) * 1991-02-18 1997-11-13 Takeda Chemical Industries Ltd Verfahren zur Herstellung von menschlichem NGF-2
US5552267A (en) * 1992-04-03 1996-09-03 The Trustees Of Columbia University In The City Of New York Solution for prolonged organ preservation
RU2142282C1 (ru) * 1993-06-04 1999-12-10 Биотайм, Инк Раствор кровезаменителя на водной основе и способ его получения
DE9422008U1 (de) * 1993-06-07 1997-08-28 Mayer, Berndt, Priv.-Doz. Dr.med., 10585 Berlin Vorrichtung zur Konservierung von Organen, Extremitäten und Gewebelappen
US5405742A (en) 1993-07-16 1995-04-11 Cyromedical Sciences, Inc. Solutions for tissue preservation and bloodless surgery and methods using same
WO1995011670A1 (en) * 1993-10-25 1995-05-04 The Liposome Company, Inc. Liposomal defensins
US5656420A (en) * 1995-02-24 1997-08-12 University Of Kentucky Research Foundation Method for employing the delta opioid dadle to extend tissue survival time during ischemia
US6258341B1 (en) * 1995-04-14 2001-07-10 Inhale Therapeutic Systems, Inc. Stable glassy state powder formulations
US5650496A (en) 1995-04-14 1997-07-22 Cephalon, Inc. IGF-I purification process
US5780429A (en) * 1995-12-22 1998-07-14 Marine Biological Laboratory Anti-LPS factor from horseshoe crabs and methods of use
US5696152A (en) 1996-05-07 1997-12-09 Wisconsin Alumni Research Foundation Taxol composition for use as organ preservation and cardioplegic agents
US5945508A (en) 1996-07-23 1999-08-31 Witten; Mark L. Substance P treatment for immunostimulation
US6642045B1 (en) * 1997-04-14 2003-11-04 Breonics, Inc. System for exsanguinous metabolic support of an organ or tissue
AU6493598A (en) * 1997-04-16 1998-11-11 White Spot Ag Biodegradable osteosynthesis implant
IT1291892B1 (it) * 1997-04-24 1999-01-21 Alessandro Lambiase Uso del nerve growth factor nella conservazione di cornee in coltura, nella produzione di tessuti corneali e congiuntivali in vitro e nella
US5834178C1 (en) * 1997-07-09 2002-04-23 Univ Wayne State Flush-storage solution for donor organs
US6576755B1 (en) * 1997-09-10 2003-06-10 Zymogenetics, Inc. Beta-defensins
US6172185B1 (en) * 1998-05-20 2001-01-09 University Of British Columbia Antimicrobial cationic peptide derivatives of bactenecin
US6045990A (en) 1998-07-09 2000-04-04 Baust; John M. Inclusion of apoptotic regulators in solutions for cell storage at low temperature

Also Published As

Publication number Publication date
US20100143876A1 (en) 2010-06-10
DE60139874D1 (de) 2009-10-22
US20020090369A1 (en) 2002-07-11
WO2002009738A1 (en) 2002-02-07
AU2001279073B2 (en) 2006-08-24
EP1305040A1 (de) 2003-05-02
US20050089836A1 (en) 2005-04-28
CA2417331A1 (en) 2002-02-07
AU7907301A (en) 2002-02-13
EP1305040B1 (de) 2009-09-09
CA2417331C (en) 2011-03-22
EP1305040A4 (de) 2004-08-18
US6696238B2 (en) 2004-02-24
US7592023B2 (en) 2009-09-22

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