DE60139874D1 - Medium für transplantat - Google Patents

Medium für transplantat

Info

Publication number
DE60139874D1
DE60139874D1 DE60139874T DE60139874T DE60139874D1 DE 60139874 D1 DE60139874 D1 DE 60139874D1 DE 60139874 T DE60139874 T DE 60139874T DE 60139874 T DE60139874 T DE 60139874T DE 60139874 D1 DE60139874 D1 DE 60139874D1
Authority
DE
Germany
Prior art keywords
media
transplant
defensins
preservation
cell surface
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60139874T
Other languages
English (en)
Inventor
Christopher J Murphy
Ted W Reid
Jonathan F Mcanulty
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of DE60139874D1 publication Critical patent/DE60139874D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0221—Freeze-process protecting agents, i.e. substances protecting cells from effects of the physical process, e.g. cryoprotectants, osmolarity regulators like oncotic agents
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0215—Disinfecting agents, e.g. antimicrobials for preserving living parts

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Reciprocating, Oscillating Or Vibrating Motors (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
DE60139874T 2000-07-28 2001-07-27 Medium für transplantat Expired - Lifetime DE60139874D1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US22163200P 2000-07-28 2000-07-28
US24960200P 2000-11-17 2000-11-17
US29093201P 2001-05-15 2001-05-15
PCT/US2001/023785 WO2002009738A1 (en) 2000-07-28 2001-07-27 Transplant media

Publications (1)

Publication Number Publication Date
DE60139874D1 true DE60139874D1 (de) 2009-10-22

Family

ID=27396971

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60139874T Expired - Lifetime DE60139874D1 (de) 2000-07-28 2001-07-27 Medium für transplantat

Country Status (7)

Country Link
US (3) US6696238B2 (de)
EP (1) EP1305040B1 (de)
AT (1) ATE442041T1 (de)
AU (2) AU2001279073B2 (de)
CA (1) CA2417331C (de)
DE (1) DE60139874D1 (de)
WO (1) WO2002009738A1 (de)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8409846B2 (en) 1997-09-23 2013-04-02 The United States Of America As Represented By The Department Of Veteran Affairs Compositions, methods and devices for maintaining an organ
US6809181B2 (en) 2000-06-01 2004-10-26 University Of Iowa Research Foundation Human beta-defensin-3 (HBD-3), a highly cationic beta-defensin antimicrobial peptide
AU2002227925A1 (en) * 2000-11-14 2002-05-27 Ipf Pharmaceuticals Gmbh Human beta-defensin-3
MXPA03011890A (es) 2001-06-22 2004-06-03 Du Pont Polinucleotidos de defensina y metodos de uso.
HK1077740A1 (en) * 2001-12-20 2006-02-24 Ct Ingenieria Genetica Biotech Use of epidermal growth factor in the manufacture of a pharmaceutical injection composition for preventing diabetic limb amputation
US7354900B2 (en) * 2002-05-03 2008-04-08 The Board Of Regents Of The University Of Oklahoma Treatment and inhibition of ocular infections and wounds by CAP37 and CAP37 peptides
FR2839311A1 (fr) * 2002-05-06 2003-11-07 Entomed Peptides antibacteriens, genes codant les peptides, vecteurs, organismes transformes, leurs preparations et les compositions les contenant
FR2841556B1 (fr) 2002-07-01 2007-07-20 Centre Nat Rech Scient Peptides ayant des proprietes antimicrobiennes et les compositions les contenant notamment pour la conservation des aliments
US20060148690A1 (en) * 2002-07-08 2006-07-06 Lydie Bougueleret Secreted peptides
EP1475434A1 (de) * 2003-05-09 2004-11-10 Oncoscience AG Verfahren zur Lagerung von Tumorzellen
US7776815B2 (en) 2004-02-24 2010-08-17 Wisconsin Alumni Research Foundation Use of neuropeptides for ligament healing
US7928059B2 (en) * 2004-02-24 2011-04-19 Wisconsin Alumni Research Foundation Use of neuropeptides for traumatic cartilage injury
US20070207209A1 (en) * 2004-08-27 2007-09-06 Murphy Christopher J Trophic factor combinations for nervous system treatment
AU2005294206B2 (en) 2004-10-07 2012-06-14 Transmedics, Inc. Systems and methods for Ex-Vivo organ care
US9301519B2 (en) * 2004-10-07 2016-04-05 Transmedics, Inc. Systems and methods for ex-vivo organ care
US8304181B2 (en) 2004-10-07 2012-11-06 Transmedics, Inc. Method for ex-vivo organ care and for using lactate as an indication of donor organ status
US12010987B2 (en) 2004-10-07 2024-06-18 Transmedics, Inc. Systems and methods for ex-vivo organ care and for using lactate as an indication of donor organ status
US9078428B2 (en) 2005-06-28 2015-07-14 Transmedics, Inc. Systems, methods, compositions and solutions for perfusing an organ
WO2007087570A2 (en) * 2006-01-24 2007-08-02 Northfield Laboratories, Inc. Polymerized hemoglobin media and its use in isolation and transplantation of islet cells
DK3178319T3 (da) * 2006-04-19 2020-02-03 Transmedics Inc Systemer til ex vivo-organpleje
US9457179B2 (en) * 2007-03-20 2016-10-04 Transmedics, Inc. Systems for monitoring and applying electrical currents in an organ perfusion system
US8114668B2 (en) * 2007-05-14 2012-02-14 Cardiac Pacemakers, Inc. Composition for cold storage of stem cells
US7892724B2 (en) * 2007-07-12 2011-02-22 Warsaw Orthopedic, Inc Method for enhancing the viability of mammalian cells, tissues and organs using a solution comprising two low molecular weight PEGs
US7960098B2 (en) * 2007-07-12 2011-06-14 Warsaw Orthoperic, Inc. Methods and compositions for the preservation of cells and tissues
US20090156488A1 (en) * 2007-09-12 2009-06-18 Zensun (Shanghai) Science & Technology Limited Use of neuregulin for organ preservation
AT505156B1 (de) * 2007-09-28 2008-11-15 Christoph Schreiber Ein neues defensin
US9247728B2 (en) * 2008-01-31 2016-02-02 Transmedics, Inc. Systems and methods for ex vivo lung care
EP2303761B1 (de) 2008-05-08 2011-08-24 Nestec S.A. Einstellen der füllmenge in einem bei einem getränkespender verwendeten becher
EP2405742A2 (de) * 2009-03-11 2012-01-18 CryoLife, Inc. Biobelastungsreduzierende antibiotikazusammensetzung und verfahren zu ihrer verwendung
KR101257228B1 (ko) 2010-06-16 2013-04-29 주식회사 나이벡 항균 또는 항염증 활성을 가지는 펩타이드 및 이를 유효성분으로 함유하는 약제학적 조성물
CN102295694B (zh) * 2010-06-28 2013-06-12 中国农业大学 一种抗菌多肽及其制备方法和应用
CA3106469A1 (en) 2011-04-14 2012-10-18 Transmedics, Inc. Organ care solution for ex-vivo machine perfusion of donor lungs
EP3384938A1 (de) 2011-09-12 2018-10-10 Moderna Therapeutics, Inc. Manipulierte nukleinsäuren und verfahren zur verwendung davon
DE18200782T1 (de) 2012-04-02 2021-10-21 Modernatx, Inc. Modifizierte polynukleotide zur herstellung von proteinen im zusammenhang mit erkrankungen beim menschen
JP2015518705A (ja) 2012-04-02 2015-07-06 モデルナ セラピューティクス インコーポレイテッドＭｏｄｅｒｎａ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． ヒト疾患に関連する生物製剤およびタンパク質の産生のための修飾ポリヌクレオチド
AR089615A1 (es) 2012-12-28 2014-09-03 Consejo Nac Invest Cient Tec Peptidos antimicrobianos, composiciones que los comprenden y usos
EP2964330B1 (de) * 2013-03-08 2022-01-12 The University of Vermont and State Agriculture College Zusammensetzungen und verfahren zur herzgewebereparatur
WO2014144004A1 (en) 2013-03-15 2014-09-18 The Board Of Trustees Of The University Of Arkansas Peptides with antifungal activity and methods of using the peptides
SI3086793T1 (sl) 2013-12-24 2022-10-28 Virginia Commonwealth University Uporaba oksigeniranih holesterol sulfatov (OCS) za zdravljenje ledvične disfunkcije
CN113287600B (zh) 2014-06-02 2022-08-19 特兰斯迈迪茨公司 对离体肝脏灌注的灌注回路和系统以及对其保存的系统
BR112017010520B1 (pt) 2014-12-12 2022-08-30 Tevosol, Inc Aparelho e método para perfusão de órgãos
IL310004A (en) 2015-09-09 2024-03-01 Transmedics Inc A tube and a catheter for a system to treat organs outside the body
AU2016353073A1 (en) 2015-11-10 2018-06-07 Visterra, Inc. Antibody molecule-drug conjugates that specifically binds to lipopolysaccharide and uses thereof
US20190350192A1 (en) * 2016-10-28 2019-11-21 Vital Therapies, Inc. Use of conditioned media from extracorporeal blood detoxifying system to supplement organ perfusion solutions
US11890319B2 (en) 2017-01-18 2024-02-06 Visterra, Inc. Antibody molecule-drug conjugates and uses thereof
FR3072246B1 (fr) * 2017-10-13 2020-06-12 Biodesiv Efnium Polymere antimicrobien pour semences animales
US11969476B2 (en) 2020-04-03 2024-04-30 Visterra, Inc. Antibody molecule-drug conjugates and uses thereof
WO2023288115A1 (en) * 2021-07-15 2023-01-19 Sio2 Medical Products, Inc. Preservative composition for nucleic acids and biological samples and methods of use
US20230056314A1 (en) * 2021-08-18 2023-02-23 Reelabs Private Limited, a Company Incorporated Under Provisions of The Companies Act 1956 Cytoprotective compositions for short-term cells storage and transportation without cryopreservation and deep freezing

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4543252A (en) 1982-01-21 1985-09-24 The Regents Of The University Of California Cationic oligopeptides having microbicidal activity
US4659692A (en) 1982-11-19 1987-04-21 The Regents Of The University Of California Cationic oligopeptides having microbicidal activity
JPS6038329A (ja) * 1983-08-11 1985-02-27 Lion Corp う蝕予防剤
US4705777A (en) 1985-02-25 1987-11-10 The Regents Of The University Of California Cationic oligopeptides having microbicidal activity
US4798824A (en) 1985-10-03 1989-01-17 Wisconsin Alumni Research Foundation Perfusate for the preservation of organs
US5410019A (en) 1987-09-24 1995-04-25 The Administrators Of The Tulane-Educational Fund Therapeutic peptides
US5470828A (en) 1987-12-24 1995-11-28 Gropep Pty. Ltd. Peptide analogs of insulin-like growth factor II
IT1219874B (it) 1988-03-18 1990-05-24 Fidia Farmaceutici Utilizzazione del fattore di crescita nervoso umano e sue composizioni farmaceutiche
US5218093A (en) 1989-03-01 1993-06-08 Allelix Biopharmaceuticals, Inc. EGF variants and pharmaceutical use thereof
US5130298A (en) 1989-05-16 1992-07-14 Ethicon, Inc. Stabilized compositions containing epidermal growth factor
IT1238348B (it) 1989-11-16 1993-07-13 Processo per la preparazione di costrutti genetici per l'espressione del fattore di crescita nervoso in cellule eucariote.
US5792831A (en) 1990-02-08 1998-08-11 Magainin Pharmaceuticals Inc. Analogues of magainin peptides containing D-amino acids
US5183805A (en) 1990-08-13 1993-02-02 Board Of Regents, The University Of Texas System Bioactive egf peptides for promotion of tissue regeneration and cancer therapy
DK0499993T3 (da) * 1991-02-18 1997-12-01 Takeda Chemical Industries Ltd Fremgangsmåde til fremstilling af human nervevækstfaktor-2
US5552267A (en) * 1992-04-03 1996-09-03 The Trustees Of Columbia University In The City Of New York Solution for prolonged organ preservation
DK0701455T3 (da) * 1993-06-04 2001-06-18 Biotime Inc Plasmalignende opløsning
DE9422008U1 (de) * 1993-06-07 1997-08-28 Mayer, Berndt, Priv.-Doz. Dr.med., 10585 Berlin Vorrichtung zur Konservierung von Organen, Extremitäten und Gewebelappen
US5405742A (en) 1993-07-16 1995-04-11 Cyromedical Sciences, Inc. Solutions for tissue preservation and bloodless surgery and methods using same
WO1995011670A1 (en) * 1993-10-25 1995-05-04 The Liposome Company, Inc. Liposomal defensins
US5656420A (en) * 1995-02-24 1997-08-12 University Of Kentucky Research Foundation Method for employing the delta opioid dadle to extend tissue survival time during ischemia
US5650496A (en) 1995-04-14 1997-07-22 Cephalon, Inc. IGF-I purification process
US6258341B1 (en) * 1995-04-14 2001-07-10 Inhale Therapeutic Systems, Inc. Stable glassy state powder formulations
US5780429A (en) * 1995-12-22 1998-07-14 Marine Biological Laboratory Anti-LPS factor from horseshoe crabs and methods of use
US5696152A (en) 1996-05-07 1997-12-09 Wisconsin Alumni Research Foundation Taxol composition for use as organ preservation and cardioplegic agents
US5945508A (en) 1996-07-23 1999-08-31 Witten; Mark L. Substance P treatment for immunostimulation
US6642045B1 (en) * 1997-04-14 2003-11-04 Breonics, Inc. System for exsanguinous metabolic support of an organ or tissue
US6214008B1 (en) * 1997-04-16 2001-04-10 White Spot Ag Biodegradable osteosynthesis implant
IT1291892B1 (it) * 1997-04-24 1999-01-21 Alessandro Lambiase Uso del nerve growth factor nella conservazione di cornee in coltura, nella produzione di tessuti corneali e congiuntivali in vitro e nella
US5834178C1 (en) * 1997-07-09 2002-04-23 Univ Wayne State Flush-storage solution for donor organs
US6576755B1 (en) * 1997-09-10 2003-06-10 Zymogenetics, Inc. Beta-defensins
US6172185B1 (en) * 1998-05-20 2001-01-09 University Of British Columbia Antimicrobial cationic peptide derivatives of bactenecin
US6045990A (en) 1998-07-09 2000-04-04 Baust; John M. Inclusion of apoptotic regulators in solutions for cell storage at low temperature

Also Published As

Publication number Publication date
US20020090369A1 (en) 2002-07-11
CA2417331C (en) 2011-03-22
AU7907301A (en) 2002-02-13
AU2001279073B2 (en) 2006-08-24
US20050089836A1 (en) 2005-04-28
US7592023B2 (en) 2009-09-22
US6696238B2 (en) 2004-02-24
EP1305040A4 (de) 2004-08-18
ATE442041T1 (de) 2009-09-15
US20100143876A1 (en) 2010-06-10
WO2002009738A1 (en) 2002-02-07
CA2417331A1 (en) 2002-02-07
EP1305040A1 (de) 2003-05-02
EP1305040B1 (de) 2009-09-09

Similar Documents

Publication Publication Date Title
DE60139874D1 (de) Medium für transplantat
DE69940019D1 (de) Einschluss apoptotischer regulatoren in lösungen zur aufbewahrung von zellen bei niedrigtemperatur
DE60122896D1 (de) Konservierungs- und lagerungsmedium für biologische materialien
ATE330467T1 (de) Lagerung von zellen, gewebe und organen in medien auf gel-basis
WO2004046308A3 (en) Methods and compositions for the preservation of cells, tissues or organs in the vitreous state
MX2007010272A (es) Inhibidores de moleculas pequenas de mdm2 y usos de los mismos.
PT1411118E (pt) Inibidores da proliferação celular contendo um anticorpo anti-glipicano 3
WO2000001231A8 (en) Improved methods for storing neural cells
UA66837C2 (uk) Похідні 3-гідроксі-4-арил-5-оксопіразоліну, які проявляють гербіцидну активність
LV12496A (en) Novel guanidine mimics as factor xa inhibitors
HK1080470B (zh) 雜環化合物
MXPA04001685A (es) Derivados de sulfonilamino empleados como herbicida.
EA200700042A1 (ru) РАСПЫЛЯЕМЫЕ В ВИДЕ АЭРОЗОЛЯ СУСПЕНЗИОННЫЕ КОМПОЗИЦИИ С TG 227ea ИЛИ TG 134a В КАЧЕСТВЕ ПРОПЕЛЛЕНТА
NO20082482L (no) Karbonylamino pyrrolpyrazoler, samt anvendelse som kinase inhibitorer
WO2000034308A3 (en) Protein transduction system and methods of use thereof
ES2133543T3 (es) Derivados de pirrolidina y oxazolidina, su preparacion y su uso como inhibidores de la agregacion de trombocitos.
WO2006060309A3 (en) Compositions and methods for ex vivo preservations of organs
MX2009002787A (es) Composiciones y métodos para prevenir el cáncer con cupredoxinas.
ES2079068T3 (es) 2-amino-6-fenil-4h-piran-4-onas antiateroscleroticas y antitromboticas.
DE50015987D1 (de) Konjugat zur vermittlung eines zell-, kompartimenttanzen
EA200701789A1 (ru) Устойчивый при хранении концентрат топлива
EP1503770A4 (de) Verfahren für die ausgedehnte lagerung von blut und blutbestandteilen
DK1423007T3 (da) Bioregulatorisk aktivstofkombination
DE60215354D1 (de) Flaschenträger
EA200100150A1 (ru) Биспиперидины в качестве противотромботических агентов

Legal Events

Date Code Title Description
8364 No opposition during term of opposition