MX2013002048A - Conjugados, particulas, composiciones y metodos relacionados. - Google Patents

Conjugados, particulas, composiciones y metodos relacionados.

Info

Publication number
MX2013002048A
MX2013002048A MX2013002048A MX2013002048A MX2013002048A MX 2013002048 A MX2013002048 A MX 2013002048A MX 2013002048 A MX2013002048 A MX 2013002048A MX 2013002048 A MX2013002048 A MX 2013002048A MX 2013002048 A MX2013002048 A MX 2013002048A
Authority
MX
Mexico
Prior art keywords
conjugates
particles
compositions
related methods
methods
Prior art date
Application number
MX2013002048A
Other languages
English (en)
Inventor
Sonke Svenson
Scott Eliasof
Oliver S Fetzer
Jungyeon Hwang
Patrick Lim Soo
Pei-Sze Ng
Donald E Bergstrom
Original Assignee
Cerulean Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cerulean Pharma Inc filed Critical Cerulean Pharma Inc
Publication of MX2013002048A publication Critical patent/MX2013002048A/es

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    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/713—Double-stranded nucleic acids or oligonucleotides
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    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/593—Polyesters, e.g. PLGA or polylactide-co-glycolide
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
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    • C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
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  • Bioinformatics & Cheminformatics (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • Wood Science & Technology (AREA)
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  • Epidemiology (AREA)
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  • Biophysics (AREA)
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Abstract

Partículas y conjugados para administrar agentes de ácido nucleico. Composiciones que contienen las partículas, los conjugados o a ambos. Métodos para utilizar las partículas, los conjugados y las composiciones.
MX2013002048A 2010-08-20 2011-08-18 Conjugados, particulas, composiciones y metodos relacionados. MX2013002048A (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US37578310P 2010-08-20 2010-08-20
US38788210P 2010-09-29 2010-09-29
US201161443972P 2011-02-17 2011-02-17
US201161475923P 2011-04-15 2011-04-15
PCT/US2011/048305 WO2012024526A2 (en) 2010-08-20 2011-08-18 Conjugates, particles, compositions, and related methods

Publications (1)

Publication Number Publication Date
MX2013002048A true MX2013002048A (es) 2013-07-03

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013002048A MX2013002048A (es) 2010-08-20 2011-08-18 Conjugados, particulas, composiciones y metodos relacionados.

Country Status (10)

Country Link
US (4) US20120225129A1 (es)
EP (1) EP2605799A4 (es)
JP (1) JP5756858B2 (es)
CN (1) CN103080313A (es)
AU (1) AU2011291582A1 (es)
BR (1) BR112013003825A2 (es)
CA (1) CA2808901A1 (es)
EA (1) EA201390145A1 (es)
MX (1) MX2013002048A (es)
WO (1) WO2012024526A2 (es)

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JP5848127B2 (ja) 2008-08-13 2016-01-27 カリフォルニア インスティテュート オブ テクノロジー 担体ナノ粒子ならびに関連する組成物、方法およびシステム
EP3578205A1 (en) 2010-08-06 2019-12-11 ModernaTX, Inc. A pharmaceutical formulation comprising engineered nucleic acids and medical use thereof
US20120237975A1 (en) 2010-10-01 2012-09-20 Jason Schrum Engineered nucleic acids and methods of use thereof
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