MX2007004479A - Compuestoss para supresion sin sentido y metodos para su uso. - Google Patents
Compuestoss para supresion sin sentido y metodos para su uso.Info
- Publication number
- MX2007004479A MX2007004479A MX2007004479A MX2007004479A MX2007004479A MX 2007004479 A MX2007004479 A MX 2007004479A MX 2007004479 A MX2007004479 A MX 2007004479A MX 2007004479 A MX2007004479 A MX 2007004479A MX 2007004479 A MX2007004479 A MX 2007004479A
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- MX
- Mexico
- Prior art keywords
- compounds
- methods
- compositions
- present
- nonsense suppression
- Prior art date
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- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
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- C07F9/65306—Five-membered rings containing two nitrogen atoms
Abstract
La presente invencion se relaciona con metodos, compuestos y composiciones para tratar o prevenir enfermedades asociadas con mutaciones sin sentido en un ARNm al administrar los compuestos o composiciones de la presente invencion; mas en particular, la presente invencion se relaciona con metodos, compuestos y composiciones para suprimir la terminacion de traduccion prematura asociada con una mutacion sin sentido en un ARNm.
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US61767004P | 2004-10-13 | 2004-10-13 | |
US61765304P | 2004-10-13 | 2004-10-13 | |
US61763304P | 2004-10-13 | 2004-10-13 | |
US61765504P | 2004-10-13 | 2004-10-13 | |
US62417004P | 2004-11-03 | 2004-11-03 | |
PCT/US2005/036673 WO2006044456A1 (en) | 2004-10-13 | 2005-10-13 | Compounds for nonsense suppression, and methods for their use |
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MX2007004479A true MX2007004479A (es) | 2007-06-18 |
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MX2007004487A MX2007004487A (es) | 2004-10-13 | 2005-10-13 | Compuestos para supresion sin sentido, y metodos para su uso. |
MX2007004479A MX2007004479A (es) | 2004-10-13 | 2005-10-13 | Compuestoss para supresion sin sentido y metodos para su uso. |
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MX2007004484A MX2007004484A (es) | 2004-10-13 | 2005-10-13 | Compuestos de pirazol o triazol y su uso para la fabricacion de un medicamento para tratar las enfermedades relacionadas con la mutacion somatica. |
MX2007004487A MX2007004487A (es) | 2004-10-13 | 2005-10-13 | Compuestos para supresion sin sentido, y metodos para su uso. |
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US (10) | US9611230B2 (es) |
EP (13) | EP2316452A1 (es) |
JP (3) | JP2008515985A (es) |
KR (3) | KR20070065429A (es) |
AU (3) | AU2005295727A1 (es) |
BR (2) | BRPI0516110A (es) |
CA (5) | CA2583177A1 (es) |
IL (3) | IL182461A0 (es) |
MX (3) | MX2007004484A (es) |
SG (2) | SG156641A1 (es) |
WO (5) | WO2006044503A2 (es) |
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