US8563573B2 - Azaindole derivatives as CFTR modulators - Google Patents

Azaindole derivatives as CFTR modulators Download PDF

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Publication number
US8563573B2
US8563573B2 US12/422,496 US42249609A US8563573B2 US 8563573 B2 US8563573 B2 US 8563573B2 US 42249609 A US42249609 A US 42249609A US 8563573 B2 US8563573 B2 US 8563573B2
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United States
Prior art keywords
1h
ml
mmol
nr
pyridin
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Active, expires
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US12/422,496
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US20090253736A1 (en
Inventor
Sara Hadida Ruah
Jinglan Zhou
Mark Miller
Brian Bear
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Vertex Pharmaceuticals Inc
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Vertex Pharmaceuticals Inc
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Priority to PCT/US2007/083464 priority Critical patent/WO2008127399A2/en
Application filed by Vertex Pharmaceuticals Inc filed Critical Vertex Pharmaceuticals Inc
Priority to US12/422,496 priority patent/US8563573B2/en
Publication of US20090253736A1 publication Critical patent/US20090253736A1/en
Assigned to VERTEX PHARMACEUTICALS INCORPORATED reassignment VERTEX PHARMACEUTICALS INCORPORATED ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: HADIDA RUAH, SARA, BEAR, BRIAN, MILLER, MARK, ZHOU, JINGLAN
Application granted granted Critical
Publication of US8563573B2 publication Critical patent/US8563573B2/en
Assigned to MACQUARIE US TRADING LLC reassignment MACQUARIE US TRADING LLC SECURITY INTEREST Assignors: VERTEX PHARMACEUTICALS (SAN DIEGO) LLC, VERTEX PHARMACEUTICALS INCORPORATED
Assigned to VERTEX PHARMACEUTICALS INCORPORATED, VERTEX PHARMACEUTICALS (SAN DIEGO) LLC reassignment VERTEX PHARMACEUTICALS INCORPORATED RELEASE BY SECURED PARTY (SEE DOCUMENT FOR DETAILS). Assignors: MACQUARIE US TRADING LLC
Assigned to VERTEX PHARAMCEUTICALS INCORPORATED reassignment VERTEX PHARAMCEUTICALS INCORPORATED CHANGE OF ADDRESS Assignors: VERTEX PHARMACEUTICALS INCORPORATED
Application status is Active legal-status Critical
Adjusted expiration legal-status Critical

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