EP1804795A4 - Enantiomeric compositions of cicletanine, alone and in combination with other agents, for the treatment of disease - Google Patents
Enantiomeric compositions of cicletanine, alone and in combination with other agents, for the treatment of diseaseInfo
- Publication number
- EP1804795A4 EP1804795A4 EP05800096A EP05800096A EP1804795A4 EP 1804795 A4 EP1804795 A4 EP 1804795A4 EP 05800096 A EP05800096 A EP 05800096A EP 05800096 A EP05800096 A EP 05800096A EP 1804795 A4 EP1804795 A4 EP 1804795A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- cicletanine
- disease
- agents
- alone
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4355—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4741—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having oxygen as a ring hetero atom, e.g. tubocuraran derivatives, noscapine, bicuculline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US61232304P | 2004-09-22 | 2004-09-22 | |
US61236904P | 2004-09-22 | 2004-09-22 | |
US11/035,231 US20060154971A1 (en) | 2005-01-13 | 2005-01-13 | Combination therapies of cicletanine and lacidipine |
US11/035,308 US20060153934A1 (en) | 2005-01-13 | 2005-01-13 | Combination therapies of cicletanine and magnesium |
US11/035,328 US20060154959A1 (en) | 2005-01-13 | 2005-01-13 | Combination therapies of cicletanine and carvedilol |
US68468405P | 2005-05-26 | 2005-05-26 | |
US11/232,724 US20060089374A1 (en) | 2003-07-17 | 2005-09-21 | Enantiomeric compositions of cicletanine, alone and in combination with other agents, for the treatment of disease |
PCT/US2005/034763 WO2006034510A2 (en) | 2004-09-22 | 2005-09-22 | Enantiomeric compositions of cicletanine, alone and in combination with other agents, for the treatment of disease |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1804795A2 EP1804795A2 (en) | 2007-07-11 |
EP1804795A4 true EP1804795A4 (en) | 2007-11-07 |
Family
ID=36090724
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP05800096A Ceased EP1804795A4 (en) | 2004-09-22 | 2005-09-22 | Enantiomeric compositions of cicletanine, alone and in combination with other agents, for the treatment of disease |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP1804795A4 (en) |
CA (1) | CA2581337A1 (en) |
WO (1) | WO2006034510A2 (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20080096915A1 (en) * | 2005-01-13 | 2008-04-24 | Greenberg Traurig LLP | Compositions for the treatment of metabolic disorders |
KR101701943B1 (en) | 2009-11-13 | 2017-02-02 | 도레이 카부시키가이샤 | Therapeutic or prophylactic agent for diabetes |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5661147A (en) * | 1993-09-03 | 1997-08-26 | Kyowa Hakko Kogyo Co., Ltd. | Imidazoquinazoline derivatives |
WO2004091612A1 (en) * | 2003-04-15 | 2004-10-28 | SynoSens Kutató és Fejlesztő Kft. | A synergistic pharmaceutical combination comprising cicletanine for the prevention or treatment of diabetes |
WO2005009446A1 (en) * | 2003-07-17 | 2005-02-03 | Cotherix, Inc. | Combination therapies for treatment of hypertension and complications in patients with diabetes or metabolic syndrome |
WO2005021039A1 (en) * | 2003-08-29 | 2005-03-10 | Cotherix, Inc. | Combination of cicletanine and an oral antidiabetic and/or blood lipid-lowering agent for treating diabetes and metabolic syndrome |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IN156817B (en) * | 1981-02-10 | 1985-11-09 | Scras |
-
2005
- 2005-09-22 WO PCT/US2005/034763 patent/WO2006034510A2/en active Application Filing
- 2005-09-22 EP EP05800096A patent/EP1804795A4/en not_active Ceased
- 2005-09-22 CA CA002581337A patent/CA2581337A1/en not_active Abandoned
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5661147A (en) * | 1993-09-03 | 1997-08-26 | Kyowa Hakko Kogyo Co., Ltd. | Imidazoquinazoline derivatives |
WO2004091612A1 (en) * | 2003-04-15 | 2004-10-28 | SynoSens Kutató és Fejlesztő Kft. | A synergistic pharmaceutical combination comprising cicletanine for the prevention or treatment of diabetes |
WO2005009446A1 (en) * | 2003-07-17 | 2005-02-03 | Cotherix, Inc. | Combination therapies for treatment of hypertension and complications in patients with diabetes or metabolic syndrome |
WO2005021039A1 (en) * | 2003-08-29 | 2005-03-10 | Cotherix, Inc. | Combination of cicletanine and an oral antidiabetic and/or blood lipid-lowering agent for treating diabetes and metabolic syndrome |
Non-Patent Citations (3)
Title |
---|
BUCHHOLZ, R.A. ET AL.: "Natriuretic and diuretic effects of cicletanine in conscious, hydrated, normotensive rats", DRUG DEVELOPMENT RESEARCH, vol. 25, 1992, pages 125 - 137, XP002452886 * |
KOHZUKI, M. ET AL.: "Renal-protective effect of nondepressor dose of cicletanine in diabetic rats with hypertension", AMERICAN JOURNAL OF HYPERTENSION, vol. 13, 2000, pages 298 - 306, XP002452885 * |
PASSA, P.: "Etude de la tolérance du ciclétanine chez des patients hypertendus présentant des troubles métaboliques", ARCH MAL COEUR, vol. 824, 1989, pages 135 - 138, XP009090138 * |
Also Published As
Publication number | Publication date |
---|---|
WO2006034510A2 (en) | 2006-03-30 |
EP1804795A2 (en) | 2007-07-11 |
CA2581337A1 (en) | 2006-03-30 |
WO2006034510A3 (en) | 2006-06-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20070420 |
|
AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR |
|
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: CORNETT, GLENN Inventor name: PAGE, JIM |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20071010 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61P 3/00 20060101ALI20071001BHEP Ipc: A61P 9/12 20060101ALI20071001BHEP Ipc: A01N 25/00 20060101ALI20071001BHEP Ipc: A61K 31/4355 20060101AFI20071001BHEP |
|
DAX | Request for extension of the european patent (deleted) | ||
17Q | First examination report despatched |
Effective date: 20090929 |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R003 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED |
|
18R | Application refused |
Effective date: 20141124 |