AU2013243955B2 - Modified polynucleotides for the production of oncology-related proteins and peptides - Google Patents

Modified polynucleotides for the production of oncology-related proteins and peptides Download PDF

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Publication number
AU2013243955B2
AU2013243955B2 AU2013243955A AU2013243955A AU2013243955B2 AU 2013243955 B2 AU2013243955 B2 AU 2013243955B2 AU 2013243955 A AU2013243955 A AU 2013243955A AU 2013243955 A AU2013243955 A AU 2013243955A AU 2013243955 B2 AU2013243955 B2 AU 2013243955B2
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Australia
Prior art keywords
oncology
pct
mrna
composition
mmrna
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AU2013243955A
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AU2013243955A1 (en
Inventor
Stephane Bancel
Tirtha Chakraborty
Antonin De Fougerolles
Kenechi Ejebe
Sayda M. ELBASHIR
Jeff Lynn Ellsworth
Justin Guild
Paul Hatala
Matthias John
Atanu Roy
Jason P. SCHRUM
Susan Whoriskey
Kristy M. WOOD
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ModernaTx Inc
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ModernaTx Inc
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Application filed by ModernaTx Inc filed Critical ModernaTx Inc
Publication of AU2013243955A1 publication Critical patent/AU2013243955A1/en
Priority to AU2018200377A priority Critical patent/AU2018200377A1/en
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Assigned to MODERNATX, INC. reassignment MODERNATX, INC. Alteration of Name(s) of Applicant(s) under S113 Assignors: MODERNA THERAPEUTICS, INC.
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    • A61K48/0066Manipulation of the nucleic acid to modify its expression pattern, e.g. enhance its duration of expression, achieved by the presence of particular introns in the delivered nucleic acid
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