|
US7030219B2
(en)
|
2000-04-28 |
2006-04-18 |
Johns Hopkins University |
B7-DC, Dendritic cell co-stimulatory molecules
|
|
ATE481985T1
(de)
|
2002-07-03 |
2010-10-15 |
Ono Pharmaceutical Co |
Immunpotenzierende zusammensetzungen
|
|
AR045563A1
(es)
|
2003-09-10 |
2005-11-02 |
Warner Lambert Co |
Anticuerpos dirigidos a m-csf
|
|
DE10347710B4
(de)
|
2003-10-14 |
2006-03-30 |
Johannes-Gutenberg-Universität Mainz |
Rekombinante Impfstoffe und deren Verwendung
|
|
KR101498834B1
(ko)
|
2005-05-09 |
2015-03-05 |
오노 야꾸힝 고교 가부시키가이샤 |
예정 사멸 인자 1(pd-1)에 대한 인간 모노클로날 항체, 및 항-pd-1 항체를 단독 사용하거나 기타 면역 요법제와 병용한 암 치료 방법
|
|
PL2397156T3
(pl)
|
2005-06-08 |
2017-07-31 |
Dana-Farber Cancer Institute, Inc. |
Sposoby i kompozycje do leczenia uporczywych infekcji i nowotworu poprzez hamowanie ścieżki zaprogramowanej śmierci komórki 1 (PD-1)
|
|
HRP20080053A2
(hr)
|
2005-07-01 |
2009-08-31 |
Medarex |
Ljudska monoklonska protutijela na ligand 1 za programiranu smrt stanice (pd-l1)
|
|
DE102005046490A1
(de)
|
2005-09-28 |
2007-03-29 |
Johannes-Gutenberg-Universität Mainz |
Modifikationen von RNA, die zu einer erhöhten Transkriptstabilität und Translationseffizienz führen
|
|
US7700567B2
(en)
|
2005-09-29 |
2010-04-20 |
Supergen, Inc. |
Oligonucleotide analogues incorporating 5-aza-cytosine therein
|
|
WO2008085562A2
(en)
*
|
2006-09-20 |
2008-07-17 |
The Johns Hopkins University |
Combinatorieal therapy of cancer and infectious diseases with anti-b7-h1 antibodies
|
|
AU2007331672A1
(en)
|
2006-12-15 |
2008-06-19 |
Ablynx N.V. |
Amino acid sequences that modulate the interaction between cells of the immune system
|
|
AU2013200388B2
(en)
*
|
2006-12-27 |
2014-10-23 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for the treatment of infections and tumors
|
|
EP2132229B1
(en)
*
|
2007-03-01 |
2016-05-11 |
Symphogen A/S |
Recombinant anti-epidermal growth factor receptor antibody compositions
|
|
CN104945508B
(zh)
|
2007-06-18 |
2019-02-22 |
默沙东有限责任公司 |
针对人程序性死亡受体pd-1的抗体
|
|
WO2009005673A1
(en)
*
|
2007-06-28 |
2009-01-08 |
Schering Corporation |
Anti-igf1r
|
|
ME02345B
(me)
*
|
2007-07-17 |
2016-08-31 |
Squibb & Sons Llc |
MONOKLONSKA ANTlTELA PROTIV GLIPIKANA-3
|
|
US8062852B2
(en)
|
2007-10-01 |
2011-11-22 |
The Children's Hospital And Regional Medical Center |
Detection and treatment of autoimmune disorders
|
|
CN105001333B
(zh)
*
|
2007-12-14 |
2019-05-17 |
诺沃—诺迪斯克有限公司 |
抗人nkg2d抗体及其用途
|
|
ES2848323T3
(es)
|
2008-01-31 |
2021-08-06 |
Inst Nat Sante Rech Med |
Anticuerpos contra CD39 humano y uso de los mismos para inhibir la actividad de las células T reguladoras
|
|
US8168757B2
(en)
|
2008-03-12 |
2012-05-01 |
Merck Sharp & Dohme Corp. |
PD-1 binding proteins
|
|
PL3208612T3
(pl)
|
2008-04-09 |
2020-03-31 |
Genentech, Inc. |
Kompozycje i sposoby leczenia chorób o podłożu immunologicznym
|
|
US20110129499A1
(en)
|
2008-05-19 |
2011-06-02 |
Paulo Maciag |
Dual delivery system for heterologous antigens
|
|
US9650639B2
(en)
|
2008-05-19 |
2017-05-16 |
Advaxis, Inc. |
Dual delivery system for heterologous antigens
|
|
US9017660B2
(en)
|
2009-11-11 |
2015-04-28 |
Advaxis, Inc. |
Compositions and methods for prevention of escape mutation in the treatment of Her2/neu over-expressing tumors
|
|
AR072999A1
(es)
|
2008-08-11 |
2010-10-06 |
Medarex Inc |
Anticuerpos humanos que se unen al gen 3 de activacion linfocitaria (lag-3) y los usos de estos
|
|
EP2662383A1
(en)
*
|
2008-08-25 |
2013-11-13 |
Amplimmune, Inc. |
PD-I antagonists and methods for treating infectious disease
|
|
JP5798919B2
(ja)
|
2008-08-25 |
2015-10-21 |
アンプリミューン、インコーポレーテッドAmplimmune, Inc. |
Pd−1アンタゴニストの組成物および使用方法
|
|
EP3133086B1
(en)
*
|
2008-09-26 |
2018-08-01 |
Dana-Farber Cancer Institute, Inc. |
Human anti-pd-1, pd-l1, and pd-l2 antibodies and uses thereof
|
|
AU2013204861B2
(en)
*
|
2008-09-26 |
2016-05-12 |
Dana-Farber Cancer Institute, Inc. |
Human anti-PD-1, PD-L1, and PD-L2 antibodies and uses therefor
|
|
CN102282265B
(zh)
|
2008-11-28 |
2020-07-24 |
埃默里大学 |
用于治疗传染病和肿瘤的方法
|
|
CA3120172A1
(en)
*
|
2008-12-09 |
2010-07-08 |
Genentech, Inc. |
Anti-pd-l1 antibodies and their use to enhance t-cell function
|
|
US8741295B2
(en)
|
2009-02-09 |
2014-06-03 |
Universite De La Mediterranee |
PD-1 antibodies and PD-L1 antibodies and uses thereof
|
|
PE20120923A1
(es)
|
2009-03-30 |
2012-08-27 |
Eisai Randd Man Co Ltd |
Composiciones farmaceuticas comprendiendo liposomas que contiene eribulina o una sal del mismo
|
|
CN102459342B
(zh)
|
2009-04-27 |
2015-01-07 |
协和发酵麒麟株式会社 |
用于治疗血液肿瘤的抗il-3ra抗体
|
|
BRPI1012675A2
(pt)
|
2009-06-26 |
2016-04-05 |
Soricimed Biopharma Inc |
compostos e métodos para a detecção de cânceres expressando trpv-6 e liberação de fármacos
|
|
CN104826106B
(zh)
|
2009-09-30 |
2019-01-11 |
斯隆凯特林防癌纪念中心 |
用于治疗癌症的组合免疫疗法
|
|
US10016617B2
(en)
|
2009-11-11 |
2018-07-10 |
The Trustees Of The University Of Pennsylvania |
Combination immuno therapy and radiotherapy for the treatment of Her-2-positive cancers
|
|
HUE037159T2
(hu)
*
|
2009-11-24 |
2018-08-28 |
Medimmune Ltd |
Targetált kötõdõ ágensek B7-H1 ellen
|
|
US20110280877A1
(en)
*
|
2010-05-11 |
2011-11-17 |
Koji Tamada |
Inhibition of B7-H1/CD80 interaction and uses thereof
|
|
CA3113343C
(en)
|
2010-06-03 |
2024-10-08 |
Pharmacyclics Llc |
USE OF BRUTON'S TYROSINE KINASE INHIBITORS IN THE TREATMENT OF FOLLICULAR LYMPHOMA
|
|
US9783578B2
(en)
|
2010-06-25 |
2017-10-10 |
Aurigene Discovery Technologies Limited |
Immunosuppression modulating compounds
|
|
US8907053B2
(en)
|
2010-06-25 |
2014-12-09 |
Aurigene Discovery Technologies Limited |
Immunosuppression modulating compounds
|
|
US9226958B2
(en)
|
2010-10-01 |
2016-01-05 |
University Of Georgia Research Foundation, Inc. |
Use of Listeria vaccine vectors to reverse vaccine unresponsiveness in parasitically infected individuals
|
|
CA2860170C
(en)
|
2010-12-22 |
2022-06-14 |
The Board Of Trustees Of The Leland Stanford Junior University |
Superagonists and antagonists of interleukin-2
|
|
WO2012125551A1
(en)
|
2011-03-11 |
2012-09-20 |
Advaxis |
Listeria-based adjuvants
|
|
US8722044B2
(en)
|
2011-03-15 |
2014-05-13 |
Janssen Biotech, Inc. |
Human tissue factor antibody and uses thereof
|
|
EP3403672A1
(en)
|
2011-04-20 |
2018-11-21 |
Medlmmune, LLC |
Antibodies and other molecules that bind b7-h1 and pd-1
|
|
WO2012149540A1
(en)
|
2011-04-28 |
2012-11-01 |
The Broad Institute Inc |
Inhibitors of histone deacetylase
|
|
HRP20230443T1
(hr)
|
2011-05-24 |
2023-09-15 |
BioNTech SE |
Individualizirana cjepiva protiv raka
|
|
CN103732238A
(zh)
|
2011-06-08 |
2014-04-16 |
奥瑞基尼探索技术有限公司 |
用于免疫调节的治疗性化合物
|
|
US11492383B2
(en)
|
2011-06-24 |
2022-11-08 |
Stephen D. Gillies |
Light chain immunoglobulin fusion proteins and methods of use thereof
|
|
EP3409278B8
(en)
|
2011-07-21 |
2020-11-04 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Heterocyclic protein kinase inhibitors
|
|
TWI835048B
(zh)
|
2011-08-01 |
2024-03-11 |
美商建南德克公司 |
利用pd-1軸結合拮抗劑及mek抑制劑治療癌症之方法
|
|
PL2750768T3
(pl)
|
2011-08-30 |
2019-05-31 |
Astex Pharmaceuticals Inc |
Formulacje pochodnej decytabiny
|
|
WO2013059740A1
(en)
|
2011-10-21 |
2013-04-25 |
Foundation Medicine, Inc. |
Novel alk and ntrk1 fusion molecules and uses thereof
|
|
MX349096B
(es)
|
2011-11-28 |
2017-07-11 |
Merck Patent Gmbh |
Anticuerpos anti-pd-l1 y sus usos.
|
|
CN104427992B
(zh)
*
|
2012-01-25 |
2017-12-19 |
德那翠丝有限公司 |
生物标志物及使用溶瘤病毒和免疫调节剂的组合疗法
|
|
SG11201405605VA
(en)
|
2012-03-12 |
2014-10-30 |
Advaxis Inc |
SUPPRESSOR CELL FUNCTION INHIBITION FOLLOWING <i>LISTERIA</i> VACCINE TREATMENT
|
|
WO2013143555A1
(en)
|
2012-03-26 |
2013-10-03 |
Biontech Ag |
Rna formulation for immunotherapy
|
|
CA2869748C
(en)
|
2012-04-12 |
2017-10-24 |
Yale University |
Vehicles for controlled delivery of different pharmaceutical agents
|
|
WO2013173223A1
(en)
|
2012-05-15 |
2013-11-21 |
Bristol-Myers Squibb Company |
Cancer immunotherapy by disrupting pd-1/pd-l1 signaling
|
|
AU2013267161A1
(en)
*
|
2012-05-31 |
2014-11-20 |
Sorrento Therapeutics, Inc. |
Antigen binding proteins that bind PD-L1
|
|
SG10201603055WA
(en)
*
|
2012-05-31 |
2016-05-30 |
Genentech Inc |
Methods Of Treating Cancer Using PD-L1 Axis Binding Antagonists And VEGF Antagonists
|
|
HUE042374T2
(hu)
|
2012-06-13 |
2019-06-28 |
Incyte Holdings Corp |
Szubsztituált triciklusos vegyületek mint FGFR inhibitorok
|
|
UY34887A
(es)
|
2012-07-02 |
2013-12-31 |
Bristol Myers Squibb Company Una Corporacion Del Estado De Delaware |
Optimización de anticuerpos que se fijan al gen de activación de linfocitos 3 (lag-3) y sus usos
|
|
CN112587658A
(zh)
|
2012-07-18 |
2021-04-02 |
博笛生物科技有限公司 |
癌症的靶向免疫治疗
|
|
US10954567B2
(en)
|
2012-07-24 |
2021-03-23 |
Pharmacyclics Llc |
Mutations associated with resistance to inhibitors of Bruton's Tyrosine Kinase (BTK)
|
|
WO2014018979A1
(en)
|
2012-07-27 |
2014-01-30 |
The Broad Institute, Inc. |
Inhibitors of histone deacetylase
|
|
WO2014022758A1
(en)
*
|
2012-08-03 |
2014-02-06 |
Dana-Farber Cancer Institute, Inc. |
Single agent anti-pd-l1 and pd-l2 dual binding antibodies and methods of use
|
|
KR101594032B1
(ko)
*
|
2012-08-23 |
2016-02-15 |
강원대학교산학협력단 |
염증 또는 피부노화의 예방 또는 치료용 약학 조성물 및 염증 또는 피부노화 개선용 화장료 조성물
|
|
AU2013308595C1
(en)
|
2012-08-30 |
2019-01-17 |
Amgen Inc. |
A method for treating melanoma using a herpes simplex virus and an immune checkpoint inhibitor
|
|
US20150290316A1
(en)
|
2012-10-02 |
2015-10-15 |
Bristol-Myers Squibb Company |
Combination of anti-kir antibodies and anti-pd-1 antibodies to treat cancer
|
|
CN107892719B
(zh)
*
|
2012-10-04 |
2022-01-14 |
达纳-法伯癌症研究所公司 |
人单克隆抗-pd-l1抗体和使用方法
|
|
EP4223770A3
(en)
|
2012-11-05 |
2023-10-18 |
Foundation Medicine, Inc. |
Novel fusion molecules and uses thereof
|
|
EP2914621B1
(en)
|
2012-11-05 |
2023-06-07 |
Foundation Medicine, Inc. |
Novel ntrk1 fusion molecules and uses thereof
|
|
AU2013351542B2
(en)
|
2012-11-28 |
2018-08-09 |
BioNTech SE |
Individualized vaccines for cancer
|
|
WO2014113729A2
(en)
|
2013-01-18 |
2014-07-24 |
Foundation Mecicine, Inc. |
Methods of treating cholangiocarcinoma
|
|
WO2014121085A1
(en)
|
2013-01-31 |
2014-08-07 |
Thomas Jefferson University |
Pd-l1 and pd-l2-based fusion proteins and uses thereof
|
|
WO2014122271A1
(en)
|
2013-02-07 |
2014-08-14 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting the survival time of patients suffering from diffuse large b-cell lymphomas
|
|
EP2958942B1
(en)
|
2013-02-20 |
2020-06-03 |
Novartis AG |
Effective targeting of primary human leukemia using anti-cd123 chimeric antigen receptor engineered t cells
|
|
KR102685501B1
(ko)
|
2013-02-20 |
2024-07-17 |
노파르티스 아게 |
인간화 항-EGFRvIII 키메라 항원 수용체를 사용한 암의 치료
|
|
EP3292873B1
(en)
|
2013-02-22 |
2019-05-01 |
CureVac AG |
Combination of vaccination and inhibition of the pd-1 pathway
|
|
AU2014220957A1
(en)
|
2013-02-22 |
2015-07-30 |
Curevac Ag |
Combination of vaccination and inhibition of the PD-1 pathway
|
|
RU2708246C2
(ru)
|
2013-03-01 |
2019-12-05 |
Астекс Фармасьютикалз, Инк. |
Комбинации лекарственных средств
|
|
RU2656597C2
(ru)
|
2013-03-06 |
2018-06-06 |
Астразенека Аб |
Хиназолиновые ингибиторы активирующих мутированных форм рецептора эпидермального фактора роста
|
|
PL2970473T3
(pl)
|
2013-03-14 |
2018-01-31 |
Bristol Myers Squibb Co |
Kombinacja agonisty dr5 i antagonisty anty-pd-1 oraz metody stosowania
|
|
WO2014151006A2
(en)
*
|
2013-03-15 |
2014-09-25 |
Genentech, Inc. |
Biomarkers and methods of treating pd-1 and pd-l1 related conditions
|
|
US9308236B2
(en)
|
2013-03-15 |
2016-04-12 |
Bristol-Myers Squibb Company |
Macrocyclic inhibitors of the PD-1/PD-L1 and CD80(B7-1)/PD-L1 protein/protein interactions
|
|
UY35468A
(es)
|
2013-03-16 |
2014-10-31 |
Novartis Ag |
Tratamiento de cáncer utilizando un receptor quimérico de antígeno anti-cd19
|
|
EP2981821B2
(en)
|
2013-04-02 |
2021-11-03 |
Merck Sharp & Dohme Corp. |
Immunohistochemical assay for detecting expression of programmed death ligand 1 (pd-l1) in tumor tissue
|
|
AU2014251087B2
(en)
|
2013-04-09 |
2019-05-02 |
Lixte Biotechnology, Inc. |
Formulations of oxabicycloheptanes and oxabicycloheptenes
|
|
SG11201508358RA
(en)
|
2013-04-09 |
2015-11-27 |
Boston Biomedical Inc |
2-acetylnaphtho[2,3-b]furan -4,9-dione for use on treating cancer
|
|
HUE036571T2
(hu)
|
2013-04-19 |
2018-07-30 |
Incyte Holdings Corp |
Biciklusos heterociklusok mint FGFR inhibitorok
|
|
WO2014180490A1
(en)
|
2013-05-10 |
2014-11-13 |
Biontech Ag |
Predicting immunogenicity of t cell epitopes
|
|
WO2014194293A1
(en)
|
2013-05-30 |
2014-12-04 |
Amplimmune, Inc. |
Improved methods for the selection of patients for pd-1 or b7-h4 targeted therapies, and combination therapies thereof
|
|
CA3175360C
(en)
*
|
2013-05-31 |
2024-05-28 |
Sorrento Therapeutics, Inc. |
Antigen binding proteins that bind pd-1
|
|
JP2016520643A
(ja)
|
2013-06-03 |
2016-07-14 |
ノバルティス アーゲー |
抗pd−l1抗体とmek阻害薬および/またはbraf阻害薬の組み合わせ物
|
|
MX384142B
(es)
|
2013-07-16 |
2025-03-14 |
Genentech Inc |
Antagonista de unión al eje pd-1 e inhibidores de tigit para usarse en el tratamiento de cáncer.
|
|
CA2920539C
(en)
|
2013-08-08 |
2024-01-02 |
Cytune Pharma |
Combined pharmaceutical composition
|
|
CN105612175B
(zh)
|
2013-08-08 |
2023-05-09 |
赛腾制药 |
基于IL-15和IL-15Rαsushi结构域的调节因子
|
|
AR097306A1
(es)
|
2013-08-20 |
2016-03-02 |
Merck Sharp & Dohme |
Modulación de la inmunidad tumoral
|
|
JP6586087B2
(ja)
|
2013-08-20 |
2019-10-02 |
メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. |
Pd−1アンタゴニストとジナシクリブとの組合せでの癌治療
|
|
EA034666B1
(ru)
|
2013-09-13 |
2020-03-04 |
Бейджин Свитзерланд Гмбх |
Антитело против pd-1 и его применение для лечения рака или вирусной инфекции и фрагмент антитела
|
|
KR20160055269A
(ko)
|
2013-09-20 |
2016-05-17 |
브리스톨-마이어스 스큅 컴퍼니 |
종양을 치료하기 위한 항-lag-3 항체 및 항-pd-1 항체의 조합물
|
|
CA2925421C
(en)
|
2013-09-24 |
2023-08-29 |
Medicenna Therapeutics, Inc. |
Interleukin-2 fusion proteins and uses thereof
|
|
WO2015048312A1
(en)
|
2013-09-26 |
2015-04-02 |
Costim Pharmaceuticals Inc. |
Methods for treating hematologic cancers
|
|
CA2926856A1
(en)
*
|
2013-10-25 |
2015-04-30 |
Dana-Farber Cancer Institute, Inc. |
Anti-pd-l1 monoclonal antibodies and fragments thereof
|
|
CN105848680A
(zh)
*
|
2013-10-25 |
2016-08-10 |
药品循环有限责任公司 |
使用布鲁顿酪氨酸激酶抑制剂和免疫疗法的治疗
|
|
WO2015066413A1
(en)
|
2013-11-01 |
2015-05-07 |
Novartis Ag |
Oxazolidinone hydroxamic acid compounds for the treatment of bacterial infections
|
|
CN105848649B
(zh)
|
2013-11-01 |
2019-08-02 |
耶鲁大学 |
用于免疫疗法的模块化粒子
|
|
AU2014348657A1
(en)
|
2013-11-13 |
2016-05-19 |
Novartis Ag |
mTOR inhibitors for enhancing the immune response
|
|
US10801070B2
(en)
|
2013-11-25 |
2020-10-13 |
The Broad Institute, Inc. |
Compositions and methods for diagnosing, evaluating and treating cancer
|
|
WO2015081158A1
(en)
|
2013-11-26 |
2015-06-04 |
Bristol-Myers Squibb Company |
Method of treating hiv by disrupting pd-1/pd-l1 signaling
|
|
WO2015085147A1
(en)
|
2013-12-05 |
2015-06-11 |
The Broad Institute Inc. |
Polymorphic gene typing and somatic change detection using sequencing data
|
|
US10241115B2
(en)
|
2013-12-10 |
2019-03-26 |
Merck Sharp & Dohme Corp. |
Immunohistochemical proximity assay for PD-1 positive cells and PD-ligand positive cells in tumor tissue
|
|
DE202014010499U1
(de)
|
2013-12-17 |
2015-10-20 |
Kymab Limited |
Targeting von humaner PCSK9 zur Cholesterinbehandlung
|
|
US9067998B1
(en)
*
|
2014-07-15 |
2015-06-30 |
Kymab Limited |
Targeting PD-1 variants for treatment of cancer
|
|
MX2016007965A
(es)
|
2013-12-17 |
2016-10-28 |
Genentech Inc |
Terapia de combinacion que comprende agonistas de union a ox40 y antagonistas de union al eje pd-1.
|
|
FI3083686T4
(fi)
*
|
2013-12-17 |
2023-05-09 |
|
Menetelmiä syöpien hoitamiseksi käyttäen pd-1-akselia sitovia antagonisteja ja taksaaneja
|
|
WO2015094992A1
(en)
|
2013-12-17 |
2015-06-25 |
Merck Sharp & Dohme Corp. |
Ifn-gamma gene signature biomarkers of tumor response to pd-1 antagonists
|
|
US9045545B1
(en)
*
|
2014-07-15 |
2015-06-02 |
Kymab Limited |
Precision medicine by targeting PD-L1 variants for treatment of cancer
|
|
SG10201809385RA
(en)
*
|
2013-12-17 |
2018-11-29 |
Genentech Inc |
Anti-cd3 antibodies and methods of use
|
|
US20150210772A1
(en)
|
2013-12-17 |
2015-07-30 |
Genentech, Inc. |
Methods of treating cancer using pd-1 axis binding antagonists and an anti-cd20 antibody
|
|
CA3225456A1
(en)
|
2013-12-19 |
2015-06-25 |
Novartis Ag |
Human mesothelin chimeric antigen receptors and uses thereof
|
|
KR20230076867A
(ko)
|
2013-12-20 |
2023-05-31 |
더 브로드 인스티튜트, 인코퍼레이티드 |
신생항원 백신과의 병용 요법
|
|
SI3466949T1
(sl)
|
2013-12-24 |
2021-03-31 |
Bristol-Myers Squibb Company |
Triciklična spojina kot sredstvo proti raku
|
|
US10835595B2
(en)
*
|
2014-01-06 |
2020-11-17 |
The Trustees Of The University Of Pennsylvania |
PD1 and PDL1 antibodies and vaccine combinations and use of same for immunotherapy
|
|
SG11201605296SA
(en)
|
2014-01-10 |
2016-07-28 |
Birdie Biopharmaceuticals Inc |
Compounds and compositions for treating her2 positive tumors
|
|
PT3094351T
(pt)
*
|
2014-01-15 |
2022-02-22 |
Kadmon Corp Llc |
Agentes imunomoduladores
|
|
JO3517B1
(ar)
|
2014-01-17 |
2020-07-05 |
Novartis Ag |
ان-ازاسبيرو الكان حلقي كبديل مركبات اريل-ان مغايرة وتركيبات لتثبيط نشاط shp2
|
|
TWI681969B
(zh)
|
2014-01-23 |
2020-01-11 |
美商再生元醫藥公司 |
針對pd-1的人類抗體
|
|
TWI680138B
(zh)
|
2014-01-23 |
2019-12-21 |
美商再生元醫藥公司 |
抗pd-l1之人類抗體
|
|
JOP20200094A1
(ar)
|
2014-01-24 |
2017-06-16 |
Dana Farber Cancer Inst Inc |
جزيئات جسم مضاد لـ pd-1 واستخداماتها
|
|
EP3575312A1
(en)
|
2014-01-27 |
2019-12-04 |
Molecular Templates, Inc. |
De-immunized shiga toxin a subunit effector polypeptides for applications in mammals
|
|
JOP20200096A1
(ar)
|
2014-01-31 |
2017-06-16 |
Children’S Medical Center Corp |
جزيئات جسم مضاد لـ tim-3 واستخداماتها
|
|
TW201613635A
(en)
|
2014-02-04 |
2016-04-16 |
Pfizer |
Combination of a PD-1 antagonist and a 4-1BB agonist for treating cancer
|
|
ES2856330T3
(es)
|
2014-02-04 |
2021-09-27 |
Incyte Corp |
Combinación de un antagonista de PD-1 y un inhibidor de IDO1 para el tratamiento del cáncer
|
|
CN118286440A
(zh)
|
2014-02-04 |
2024-07-05 |
辉瑞大药厂 |
用于治疗癌症的pd-1拮抗剂和vegfr抑制剂的组合
|
|
NZ721364A
(en)
|
2014-02-10 |
2023-04-28 |
Merck Patent Gmbh |
Targeted tgfβ inhibition
|
|
GB201403775D0
(en)
|
2014-03-04 |
2014-04-16 |
Kymab Ltd |
Antibodies, uses & methods
|
|
WO2015134605A1
(en)
|
2014-03-05 |
2015-09-11 |
Bristol-Myers Squibb Company |
Treatment of renal cancer using a combination of an anti-pd-1 antibody and another anti-cancer agent
|
|
US11142584B2
(en)
|
2014-03-11 |
2021-10-12 |
Molecular Templates, Inc. |
CD20-binding proteins comprising Shiga toxin A subunit effector regions for inducing cellular internalization and methods using same
|
|
EP3590529A1
(en)
|
2014-03-12 |
2020-01-08 |
CureVac AG |
Combination of vaccination and ox40 agonists
|
|
US10618963B2
(en)
|
2014-03-12 |
2020-04-14 |
Yeda Research And Development Co. Ltd |
Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS
|
|
CN106687125B
(zh)
|
2014-03-12 |
2021-12-14 |
耶达研究与开发有限公司 |
降低系统性调节性t细胞水平或活性来治疗cns疾病和损伤
|
|
US10519237B2
(en)
|
2014-03-12 |
2019-12-31 |
Yeda Research And Development Co. Ltd |
Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS
|
|
ES2770684T3
(es)
|
2014-03-14 |
2020-07-02 |
Novartis Ag |
Moléculas de anticuerpos contra LAG-3 y usos de los mismos
|
|
CN106163547A
(zh)
|
2014-03-15 |
2016-11-23 |
诺华股份有限公司 |
使用嵌合抗原受体治疗癌症
|
|
JP2017509336A
(ja)
|
2014-03-20 |
2017-04-06 |
ファーマサイクリックス エルエルシー |
ホスホリパーゼcガンマ2及び耐性に関連した変異
|
|
SI3122745T1
(sl)
|
2014-03-24 |
2019-05-31 |
Novartis Ag |
Organske spojine monobaktama za zdravljenje bakterijskih infekcij
|
|
EP3122884B1
(en)
*
|
2014-03-26 |
2019-12-25 |
Tocagen Inc. |
A retroviral vector having immune-stimulating activity
|
|
JP6637439B2
(ja)
|
2014-03-31 |
2020-01-29 |
ジェネンテック, インコーポレイテッド |
抗ox40抗体及び使用方法
|
|
CA2943834A1
(en)
|
2014-03-31 |
2015-10-08 |
Genentech, Inc. |
Combination therapy comprising anti-angiogenesis agents and ox40 binding agonists
|
|
US9987258B2
(en)
|
2014-04-06 |
2018-06-05 |
H. Lee Moffitt Cancer Center And Research Institute, Inc. |
Histone deacetylase as a modulator of PDL1 expression and activity
|
|
CN111514283B
(zh)
|
2014-04-07 |
2025-10-14 |
诺华股份有限公司 |
使用抗cd19嵌合抗原受体治疗癌症
|
|
US20170044496A1
(en)
|
2014-04-10 |
2017-02-16 |
H. Lee Moffitt Cancer Center And Research Institute, Inc. |
Enhanced Expansion of Tumor-Infiltrating Lymphocytes for Adoptive Cell Therapy
|
|
EP3134102B1
(en)
|
2014-04-24 |
2019-07-03 |
The Board of Trustees of The Leland Stanford Junior University |
Superagonists, partial agonists and antagonists of interleukin-2
|
|
KR20230165876A
(ko)
*
|
2014-05-13 |
2023-12-05 |
메디뮨 리미티드 |
비-소세포 폐암을 치료하기 위한 항-b7-h1 및 항-ctla-4 항체
|
|
CA2949121A1
(en)
|
2014-05-15 |
2015-11-19 |
Bristol-Myers Squibb Company |
Treatment of lung cancer using a combination of an anti-pd-1 antibody and another anti-cancer agent
|
|
US20170182003A1
(en)
|
2014-05-23 |
2017-06-29 |
Eisai R&D Management Co., Ltd. |
Combination therapies for the treatment of cancer
|
|
KR20170005492A
(ko)
|
2014-05-28 |
2017-01-13 |
아이데닉스 파마슈티칼스 엘엘씨 |
암의 치료를 위한 뉴클레오시드 유도체
|
|
WO2015184061A2
(en)
*
|
2014-05-28 |
2015-12-03 |
Dana-Farber Cancer Institute, Inc. |
Activating jak kinase biomarkers predictive of anti-immune checkpoint inhibitor response
|
|
RU2016149812A
(ru)
|
2014-06-06 |
2018-07-17 |
Флексус Байосайенсиз, Инк. |
Иммунорегулирующие средства
|
|
SG10201810507WA
(en)
|
2014-06-06 |
2018-12-28 |
Bristol Myers Squibb Co |
Antibodies against glucocorticoid-induced tumor necrosis factor receptor (gitr) and uses thereof
|
|
CA2947048C
(en)
|
2014-06-11 |
2023-10-17 |
Molecular Templates, Inc. |
Protease-cleavage resistant, shiga toxin a subunit effector polypeptides and cell-targeted molecules comprising the same
|
|
TWI693232B
(zh)
|
2014-06-26 |
2020-05-11 |
美商宏觀基因股份有限公司 |
與pd-1和lag-3具有免疫反應性的共價結合的雙抗體和其使用方法
|
|
KR102130600B1
(ko)
*
|
2014-07-03 |
2020-07-08 |
베이진 엘티디 |
Pd-l1 항체와 이를 이용한 치료 및 진단
|
|
CN107074958A
(zh)
|
2014-07-09 |
2017-08-18 |
博笛生物科技有限公司 |
用于治疗肿瘤的抗‑pd‑l1组合
|
|
MY188940A
(en)
*
|
2014-07-11 |
2022-01-13 |
Ventana Med Syst Inc |
Anti-pd-l1 antibodies and diagnostic uses thereof
|
|
SG11201700074YA
(en)
|
2014-07-15 |
2017-02-27 |
Genentech Inc |
Compositions for treating cancer using pd-1 axis binding antagonists and mek inhibitors
|
|
US9139648B1
(en)
|
2014-07-15 |
2015-09-22 |
Kymab Limited |
Precision medicine by targeting human NAV1.9 variants for treatment of pain
|
|
MX2017000857A
(es)
|
2014-07-18 |
2017-10-11 |
Advaxis Inc |
Combinación de un antagonista de la proteina de muerte programada (pd-1) y una vacuna basada en listeria para tratar el cáncer de próstata.
|
|
US11542488B2
(en)
|
2014-07-21 |
2023-01-03 |
Novartis Ag |
Sortase synthesized chimeric antigen receptors
|
|
MX2017001011A
(es)
|
2014-07-21 |
2018-05-28 |
Novartis Ag |
Tratamiento de cancer de usando un receptor quimerico de antigeno anti-bcma.
|
|
EP3172234B1
(en)
|
2014-07-21 |
2020-04-08 |
Novartis AG |
Treatment of cancer using a cd33 chimeric antigen receptor
|
|
WO2016014530A1
(en)
|
2014-07-21 |
2016-01-28 |
Novartis Ag |
Combinations of low, immune enhancing. doses of mtor inhibitors and cars
|
|
CA2955788C
(en)
|
2014-07-22 |
2024-01-16 |
Ziyong Sun |
Anti-pd-1 antibodies
|
|
WO2016019300A1
(en)
|
2014-07-31 |
2016-02-04 |
Novartis Ag |
Subset-optimized chimeric antigen receptor-containing t-cells
|
|
SG10201901057UA
(en)
*
|
2014-08-05 |
2019-03-28 |
Cb Therapeutics Inc |
Anti-pd-l1 antibodies
|
|
CN107001316A
(zh)
|
2014-08-06 |
2017-08-01 |
诺华股份有限公司 |
作为抗菌剂的喹诺酮衍生物
|
|
CN106794246B
(zh)
*
|
2014-08-08 |
2021-10-15 |
OncoQuest制药有限公司 |
肿瘤抗原特异性抗体和tlr3刺激以增强检查点干扰癌症疗法的性能
|
|
DK3177640T3
(da)
*
|
2014-08-08 |
2020-08-10 |
Univ Leland Stanford Junior |
Pd-1-midler med høj affinitet og anvendelsesfremgangsmåder
|
|
US10166273B2
(en)
|
2014-08-12 |
2019-01-01 |
The Board Of Trustees Of The Leland Stanford Junior University |
Synergistic tumor treatment with antibodies targeting PD-1, PD-L1 or CTLA4 and integrin-binding-Fc-fusion protein
|
|
WO2016025645A1
(en)
|
2014-08-12 |
2016-02-18 |
Massachusetts Institute Of Technology |
Synergistic tumor treatment with il-2, a therapeutic antibody, and an immune checkpoint blocker
|
|
CA2958200A1
(en)
|
2014-08-14 |
2016-02-18 |
Novartis Ag |
Treatment of cancer using a gfr alpha-4 chimeric antigen receptor
|
|
AU2015305531B2
(en)
|
2014-08-19 |
2021-05-20 |
Novartis Ag |
Anti-CD123 chimeric antigen receptor (CAR) for use in cancer treatment
|
|
JP2017530950A
(ja)
|
2014-08-25 |
2017-10-19 |
ファイザー・インコーポレイテッド |
癌を処置するためのpd−1アンタゴニストおよびalk阻害剤の併用
|
|
WO2016030455A1
(en)
*
|
2014-08-28 |
2016-03-03 |
Medimmune Limited |
Anti-b7-h1 and anti-ctla-4 antibodies for treating non-small lung cancer
|
|
PT3186281T
(pt)
|
2014-08-28 |
2019-07-10 |
Halozyme Inc |
Terapia de combinação com uma enzima de degradação de hialuronano e um inibidor de pontos de verificação imunológica
|
|
CN112546238A
(zh)
|
2014-09-01 |
2021-03-26 |
博笛生物科技有限公司 |
用于治疗肿瘤的抗-pd-l1结合物
|
|
US9535074B2
(en)
|
2014-09-08 |
2017-01-03 |
Merck Sharp & Dohme Corp. |
Immunoassay for soluble PD-L1
|
|
RU2718914C2
(ru)
|
2014-09-13 |
2020-04-15 |
Новартис Аг |
Сочетанные способы лечения с использованием ингибиторов alk
|
|
KR20250007689A
(ko)
|
2014-09-16 |
2025-01-14 |
이나뜨 파르마 에스.에이. |
림프구에서의 억제 경로의 중화
|
|
ES2891332T3
(es)
|
2014-09-17 |
2022-01-27 |
Novartis Ag |
Direccionamiento a células citotóxicas con receptores quiméricos para la inmunoterapia adoptiva
|
|
US20160082120A1
(en)
|
2014-09-23 |
2016-03-24 |
Genentech, Inc. |
METHODS OF USING ANTI-CD79b IMMUNOCONJUGATES
|
|
WO2016045732A1
(en)
|
2014-09-25 |
2016-03-31 |
Biontech Rna Pharmaceuticals Gmbh |
Stable formulations of lipids and liposomes
|
|
ES2853823T3
(es)
*
|
2014-09-30 |
2021-09-17 |
Intervet Int Bv |
Anticuerpos de PD-L1 que se unen a PD-L1 canino
|
|
EP3200775B1
(en)
|
2014-10-03 |
2019-11-20 |
Novartis AG |
Combination therapies
|
|
MA41044A
(fr)
|
2014-10-08 |
2017-08-15 |
Novartis Ag |
Compositions et procédés d'utilisation pour une réponse immunitaire accrue et traitement contre le cancer
|
|
US10774388B2
(en)
|
2014-10-08 |
2020-09-15 |
Novartis Ag |
Biomarkers predictive of therapeutic responsiveness to chimeric antigen receptor therapy and uses thereof
|
|
KR102536786B1
(ko)
|
2014-10-10 |
2023-05-26 |
이나뜨 파르마 에스.에이. |
Cd73 차단
|
|
KR20170072244A
(ko)
|
2014-10-10 |
2017-06-26 |
이데라 파마슈티칼즈, 인코포레이티드 |
관문 억제제를 가지는 tlr9 효능제를 이용한 암 치료
|
|
US9732119B2
(en)
|
2014-10-10 |
2017-08-15 |
Bristol-Myers Squibb Company |
Immunomodulators
|
|
BR112017007765B1
(pt)
|
2014-10-14 |
2023-10-03 |
Halozyme, Inc |
Composições de adenosina deaminase-2 (ada2), variantes do mesmo e métodos de usar o mesmo
|
|
US9988452B2
(en)
|
2014-10-14 |
2018-06-05 |
Novartis Ag |
Antibody molecules to PD-L1 and uses thereof
|
|
WO2016062722A1
(en)
|
2014-10-24 |
2016-04-28 |
Astrazeneca Ab |
Combination
|
|
DK3215518T3
(da)
|
2014-10-29 |
2021-05-25 |
Bicyclerd Ltd |
Bicykliske peptidligander, der er specifikke for mt1-mmp
|
|
PL3212670T3
(pl)
|
2014-10-29 |
2021-06-14 |
Five Prime Therapeutics, Inc. |
Leczenie skojarzone nowotworów
|
|
JP7372728B2
(ja)
|
2014-10-31 |
2023-11-01 |
ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア |
改変t細胞に関する方法および組成物
|
|
MX382902B
(es)
*
|
2014-10-31 |
2025-03-13 |
Oncomed Pharm Inc |
Inhibidor de la vía noth en combinación con un agente inmunoterapéutico para usarse en el tratamiento de cáncer.
|
|
RU2017119009A
(ru)
|
2014-11-03 |
2018-12-05 |
Дженентек, Инк. |
Анализы для обнаружения субпопуляций иммунных т-клеток и способы их применения
|
|
JP2017536842A
(ja)
|
2014-11-03 |
2017-12-14 |
ジェネンテック, インコーポレイテッド |
Ox40アゴニスト治療薬の有効性及び評価を予測するための方法及びバイオマーカー
|
|
AR102537A1
(es)
|
2014-11-05 |
2017-03-08 |
Flexus Biosciences Inc |
Agentes inmunomoduladores
|
|
EA201790806A1
(ru)
|
2014-11-05 |
2017-11-30 |
Флексус Байосайенсиз, Инк. |
Иммунорегулирующие средства
|
|
US11236139B2
(en)
|
2014-11-05 |
2022-02-01 |
The Regents Of The University Of California |
Combination immunotherapy
|
|
UY36390A
(es)
|
2014-11-05 |
2016-06-01 |
Flexus Biosciences Inc |
Compuestos moduladores de la enzima indolamina 2,3-dioxigenasa (ido), sus métodos de síntesis y composiciones farmacéuticas que los contienen
|
|
SG11201703464UA
(en)
|
2014-11-14 |
2017-05-30 |
Novartis Ag |
Antibody drug conjugates
|
|
US9856292B2
(en)
|
2014-11-14 |
2018-01-02 |
Bristol-Myers Squibb Company |
Immunomodulators
|
|
JP2017537090A
(ja)
|
2014-11-17 |
2017-12-14 |
ジェネンテック, インコーポレイテッド |
Ox40結合アゴニスト及びpd−1軸結合アンタゴニストを含む併用療法
|
|
WO2016081854A1
(en)
|
2014-11-20 |
2016-05-26 |
Promega Corporation |
Systems and methods for assessing modulators of immune checkpoints
|
|
JP6944369B2
(ja)
|
2014-11-20 |
2021-10-06 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
T細胞活性化二重特異性抗原結合分子cd3 abd葉酸受容体1(folr1)及びpd−1軸結合アンタゴニストの併用療法
|
|
HUE050596T2
(hu)
|
2014-11-21 |
2020-12-28 |
Bristol Myers Squibb Co |
Antitestek CD73 ellen és azok felhasználásai
|
|
HUE052526T2
(hu)
|
2014-11-21 |
2021-05-28 |
Bristol Myers Squibb Co |
Antitestek, amelyek tartalmaznak módosított nehéz konstans régiókat
|
|
CN114591420A
(zh)
|
2014-11-25 |
2022-06-07 |
百时美施贵宝公司 |
用于成像的新型pd-l1结合多肽
|
|
EP4218832A3
(en)
|
2014-11-25 |
2023-08-23 |
Bristol-Myers Squibb Company |
Methods and compositions for 18f-radiolabeling of the fibronectin type (iii) domain
|
|
WO2016086200A1
(en)
|
2014-11-27 |
2016-06-02 |
Genentech, Inc. |
4,5,6,7-tetrahydro-1 h-pyrazolo[4,3-c]pyridin-3-amine compounds as cbp and/or ep300 inhibitors
|
|
WO2016090034A2
(en)
|
2014-12-03 |
2016-06-09 |
Novartis Ag |
Methods for b cell preconditioning in car therapy
|
|
WO2016090070A1
(en)
|
2014-12-04 |
2016-06-09 |
Bristol-Myers Squibb Company |
Combination of anti-cs1 and anti-pd1 antibodies to treat cancer (myeloma)
|
|
JP2017537929A
(ja)
|
2014-12-05 |
2017-12-21 |
ジェネンテック, インコーポレイテッド |
Pd−1軸アンタゴニスト及びhpk1アンタゴニストを用いたがん治療のための方法及び組成物
|
|
US10442819B2
(en)
|
2014-12-05 |
2019-10-15 |
Merck Sharp & Dohme Corp. |
Tricyclic compounds as inhibitors of mutant IDH enzymes
|
|
EP3226690B1
(en)
|
2014-12-05 |
2020-05-20 |
Merck Sharp & Dohme Corp. |
Novel tricyclic compounds as inhibitors of mutant idh enzymes
|
|
US10508108B2
(en)
|
2014-12-05 |
2019-12-17 |
Merck Sharp & Dohme Corp. |
Tricyclic compounds as inhibitors of mutant IDH enzymes
|
|
EP3230498B1
(en)
|
2014-12-09 |
2023-01-18 |
Merck Sharp & Dohme LLC |
System and methods for deriving gene signature biomarkers of response to pd-1 antagonists
|
|
WO2016094481A1
(en)
*
|
2014-12-09 |
2016-06-16 |
Regeneron Pharmaceuticals, Inc. |
Non-human animals having a humanized cluster of differentiation 274 gene
|
|
MA41185B1
(fr)
|
2014-12-16 |
2019-12-31 |
Novartis Ag |
Composés d'acide isoxazole hydroxamique comme inhibiteurs de lpxc
|
|
US9861680B2
(en)
|
2014-12-18 |
2018-01-09 |
Bristol-Myers Squibb Company |
Immunomodulators
|
|
MX2017008013A
(es)
|
2014-12-18 |
2018-03-06 |
Amgen Inc |
Formulacion congelada estable de virus de herpes simple.
|
|
US10975442B2
(en)
|
2014-12-19 |
2021-04-13 |
Massachusetts Institute Of Technology |
Molecular biomarkers for cancer immunotherapy
|
|
WO2016100977A1
(en)
|
2014-12-19 |
2016-06-23 |
The Broad Institute Inc. |
Methods for profiling the t-cel- receptor repertoire
|
|
US20170340733A1
(en)
|
2014-12-19 |
2017-11-30 |
Novartis Ag |
Combination therapies
|
|
US9944678B2
(en)
|
2014-12-19 |
2018-04-17 |
Bristol-Myers Squibb Company |
Immunomodulators
|
|
AR103232A1
(es)
|
2014-12-22 |
2017-04-26 |
Bristol Myers Squibb Co |
ANTAGONISTAS DE TGFbR
|
|
MX389267B
(es)
|
2014-12-23 |
2025-03-20 |
Bristol Myers Squibb Co |
Anticuerpos contra el inmunorreceptor de células t con dominios de inmunoglobulina y de porción inhibidora con base en tirosina del inmumorreceptor (tigit).
|
|
AU2015374385B2
(en)
|
2014-12-31 |
2020-08-06 |
Checkmate Pharmaceuticals, Inc. |
Combination tumor immunotherapy
|
|
GB201500319D0
(en)
|
2015-01-09 |
2015-02-25 |
Agency Science Tech & Res |
Anti-PD-L1 antibodies
|
|
PE20171185A1
(es)
|
2015-01-14 |
2017-08-22 |
Bristol Myers Squibb Co |
Dimeros de benzodiazepina unidos con puentes de heteroarileno, conjugados de estos, y sus metodos de preparacion y uso
|
|
MA41414A
(fr)
|
2015-01-28 |
2017-12-05 |
Centre Nat Rech Scient |
Protéines de liaison agonistes d' icos
|
|
WO2016123573A1
(en)
|
2015-01-30 |
2016-08-04 |
President And Fellows Of Harvard College |
Peritumoral and intratumoral materials for cancer therapy
|
|
ES2947589T3
(es)
*
|
2015-01-31 |
2023-08-11 |
Univ Pennsylvania |
Composiciones y métodos para el suministro de moléculas terapéuticas a linfocitos T
|
|
WO2016126608A1
(en)
|
2015-02-02 |
2016-08-11 |
Novartis Ag |
Car-expressing cells against multiple tumor antigens and uses thereof
|
|
MA41460A
(fr)
|
2015-02-03 |
2017-12-12 |
Oncomed Pharm Inc |
Agents de liaison à la tnfrsf et leurs utilisations
|
|
US20160222060A1
(en)
|
2015-02-04 |
2016-08-04 |
Bristol-Myers Squibb Company |
Immunomodulators
|
|
WO2016127052A1
(en)
|
2015-02-05 |
2016-08-11 |
Bristol-Myers Squibb Company |
Cxcl11 and smica as predictive biomarkers for efficacy of anti-ctla4 immunotherapy
|
|
CN108064247B
(zh)
*
|
2015-02-05 |
2022-06-03 |
分子模板公司 |
包含志贺毒素a亚基效应物区域的多价cd20结合分子及其富集组合物
|
|
WO2016128060A1
(en)
|
2015-02-12 |
2016-08-18 |
Biontech Ag |
Predicting t cell epitopes useful for vaccination
|
|
MX388991B
(es)
|
2015-02-20 |
2025-03-20 |
Incyte Corp |
Heterociclos biciclicos como inhibidores de receptores del factor de crecimiento fibroblastico (fgfr)
|
|
MA41551A
(fr)
|
2015-02-20 |
2017-12-26 |
Incyte Corp |
Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4
|
|
RU2742312C1
(ru)
*
|
2015-02-26 |
2021-02-04 |
Мерк Патент Гмбх |
Ингибиторы pd-1 / pd-l1 для лечения рака
|
|
IL278423B2
(en)
|
2015-02-26 |
2024-04-01 |
Merck Patent Gmbh |
Pd-1 / pd-l1 inhibitors for the treatment of cancer
|
|
PE20171789A1
(es)
|
2015-03-02 |
2017-12-28 |
Bristol Myers Squibb Co |
Inhibidores del factor beta de crecimiento de transformacion (tgf-beta)
|
|
AU2015384801B2
(en)
|
2015-03-04 |
2022-01-06 |
Eisai R&D Management Co., Ltd. |
Combination of a PD-1 antagonist and a VEGFR/FGFR/RET tyrosine kinase inhibitor for treating cancer
|
|
WO2016141209A1
(en)
|
2015-03-04 |
2016-09-09 |
Merck Sharp & Dohme Corp. |
Combination of a pd-1 antagonist and eribulin for treating cancer
|
|
AU2016229294B2
(en)
|
2015-03-06 |
2021-11-04 |
Beyondspring Pharmaceuticals, Inc. |
Method of treating cancer associated with a RAS mutation
|
|
MX385914B
(es)
|
2015-03-06 |
2025-03-18 |
Beyondspring Pharmaceuticals Inc |
Método para tratar un tumor cerebral
|
|
US20180044429A1
(en)
|
2015-03-09 |
2018-02-15 |
Celldex Therapeutics, Inc. |
Cd27 agonists
|
|
BR112017018908A2
(pt)
|
2015-03-10 |
2018-04-17 |
Aduro Biotech, Inc. |
composições e métodos para ativar a sinalização dependente do "estimulador do gene de interferon
|
|
EP3067062A1
(en)
|
2015-03-13 |
2016-09-14 |
Ipsen Pharma S.A.S. |
Combination of tasquinimod or a pharmaceutically acceptable salt thereof and a pd1 and/or pdl1 inhibitor, for use as a medicament
|
|
SG11201707383PA
(en)
*
|
2015-03-13 |
2017-10-30 |
Cytomx Therapeutics Inc |
Anti-pdl1 antibodies, activatable anti-pdl1 antibodies, and methods of use thereof
|
|
US9809625B2
(en)
|
2015-03-18 |
2017-11-07 |
Bristol-Myers Squibb Company |
Immunomodulators
|
|
RU2739163C2
(ru)
|
2015-03-23 |
2020-12-21 |
Байер Фарма Акциенгезельшафт |
Анти-сеасам6 антитела и их применения
|
|
CA2981584A1
(en)
|
2015-04-03 |
2016-10-06 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase for the treatment of cancer
|
|
WO2016161410A2
(en)
|
2015-04-03 |
2016-10-06 |
Xoma Technology Ltd. |
Treatment of cancer using inhibitors of tgf-beta and pd-1
|
|
US10478494B2
(en)
|
2015-04-03 |
2019-11-19 |
Astex Therapeutics Ltd |
FGFR/PD-1 combination therapy for the treatment of cancer
|
|
EP3280795B1
(en)
|
2015-04-07 |
2021-03-24 |
Novartis AG |
Combination of chimeric antigen receptor therapy and amino pyrimidine derivatives
|
|
JP6955445B2
(ja)
|
2015-04-07 |
2021-10-27 |
ジェネンテック, インコーポレイテッド |
アゴニスト性の活性を有する抗原結合複合体及びその使用方法
|
|
ES2899227T3
(es)
|
2015-04-07 |
2022-03-10 |
Alector Llc |
Anticuerpos anti sortilina y métodos de uso de los mismos
|
|
WO2016162505A1
(en)
|
2015-04-08 |
2016-10-13 |
F-Star Biotechnology Limited |
Her2 binding agent therapies
|
|
GB201506411D0
(en)
|
2015-04-15 |
2015-05-27 |
Bergenbio As |
Humanized anti-axl antibodies
|
|
US11326211B2
(en)
|
2015-04-17 |
2022-05-10 |
Merck Sharp & Dohme Corp. |
Blood-based biomarkers of tumor sensitivity to PD-1 antagonists
|
|
WO2016168595A1
(en)
|
2015-04-17 |
2016-10-20 |
Barrett David Maxwell |
Methods for improving the efficacy and expansion of chimeric antigen receptor-expressing cells
|
|
SG10201912035YA
(en)
|
2015-04-17 |
2020-02-27 |
Bristol Myers Squibb Co |
Compositions comprising a combination of an anti-pd-1 antibody and another antibody
|
|
WO2016172583A1
(en)
|
2015-04-23 |
2016-10-27 |
Novartis Ag |
Treatment of cancer using chimeric antigen receptor and protein kinase a blocker
|
|
JP2018515474A
(ja)
|
2015-04-28 |
2018-06-14 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
抗pd−1抗体を使用するpd−l1陽性黒色腫の処置
|
|
WO2016176503A1
(en)
|
2015-04-28 |
2016-11-03 |
Bristol-Myers Squibb Company |
Treatment of pd-l1-negative melanoma using an anti-pd-1 antibody and an anti-ctla-4 antibody
|
|
ES2815683T3
(es)
|
2015-05-11 |
2021-03-30 |
Bristol Myers Squibb Co |
Compuestos tricíclicos como agentes antineoplásicos
|
|
US10174024B2
(en)
|
2015-05-12 |
2019-01-08 |
Bristol-Myers Squibb Company |
5H-pyrido[3,2-B]indole compounds as anticancer agents
|
|
US9725449B2
(en)
|
2015-05-12 |
2017-08-08 |
Bristol-Myers Squibb Company |
Tricyclic compounds as anticancer agents
|
|
IL295002A
(en)
|
2015-05-12 |
2022-09-01 |
Genentech Inc |
Therapeutic and diagnostic methods for cancer containing a pd–l1 binding antagonist
|
|
PT3298021T
(pt)
|
2015-05-18 |
2019-08-05 |
Tolero Pharmaceuticals Inc |
Pró-fármacos de alvocidib possuindo biodisponibilidade aumentada
|
|
EP3297672B1
(en)
|
2015-05-21 |
2021-09-01 |
Harpoon Therapeutics, Inc. |
Trispecific binding proteins and methods of use
|
|
CN108368147A
(zh)
|
2015-05-27 |
2018-08-03 |
南方研究院 |
用于治疗癌症的核苷酸
|
|
US20180155429A1
(en)
|
2015-05-28 |
2018-06-07 |
Bristol-Myers Squibb Company |
Treatment of pd-l1 positive lung cancer using an anti-pd-1 antibody
|
|
HRP20201031T1
(hr)
|
2015-05-29 |
2020-10-16 |
Agenus Inc. |
Anti-ctla-4 protutijela i postupci njihove upotrebe
|
|
CA2987410A1
(en)
|
2015-05-29 |
2016-12-08 |
Bristol-Myers Squibb Company |
Antibodies against ox40 and uses thereof
|
|
ES2789500T5
(es)
|
2015-05-29 |
2023-09-20 |
Hoffmann La Roche |
Procedimientos terapéuticos y de diagnóstico para el cáncer
|
|
WO2016196389A1
(en)
|
2015-05-29 |
2016-12-08 |
Bristol-Myers Squibb Company |
Treatment of renal cell carcinoma
|
|
HK1255200A1
(zh)
|
2015-05-29 |
2019-08-09 |
F. Hoffmann-La Roche Ag |
癌症中pd-l1启动子甲基化
|
|
US10751412B2
(en)
|
2015-05-29 |
2020-08-25 |
Merck Sharp & Dohme Corp. |
Combination of a PD-1 antagonist and CPG-C type oligonucleotide for treating cancer
|
|
EP3303373B1
(en)
|
2015-05-30 |
2020-04-08 |
Molecular Templates, Inc. |
De-immunized, shiga toxin a subunit scaffolds and cell-targeting molecules comprising the same
|
|
EP3302467A4
(en)
|
2015-05-31 |
2019-01-02 |
Curegenix Corporation |
Combination compositions for immunotherapy
|
|
MX2017015618A
(es)
|
2015-06-03 |
2018-08-15 |
Boston Biomedical Inc |
Composiciones que comprenden un inhibidor de la autorrenovación y diferenciación de células madre cancerosas y un agente inmunoterapéutico para su uso en el tratamiento del cáncer.
|
|
AU2016274584A1
(en)
|
2015-06-08 |
2018-01-04 |
Genentech, Inc. |
Methods of treating cancer using anti-OX40 antibodies and PD-1 axis binding antagonists
|
|
CN107810011A
(zh)
|
2015-06-08 |
2018-03-16 |
豪夫迈·罗氏有限公司 |
使用抗ox40抗体治疗癌症的方法
|
|
EP3307777A4
(en)
|
2015-06-11 |
2019-02-13 |
Wuxi Biologics (Shanghai) Co. Ltd. |
NOVEL ANTI-PD-L1 ANTIBODIES
|
|
EA201792522A1
(ru)
|
2015-06-12 |
2018-05-31 |
Бристол-Майерс Сквибб Компани |
Лечение злокачественной опухоли с помощью комбинированной блокады сигнальных путей pd-1 и cxcr4
|
|
TWI870335B
(zh)
|
2015-06-12 |
2025-01-21 |
美商宏觀基因股份有限公司 |
變異的嵌合4d5抗體及其與抗pd-1抗體聯合用於治療癌症的應用
|
|
RU2766890C2
(ru)
|
2015-06-16 |
2022-03-16 |
Мерк Патент Гмбх |
Комбинированные способы лечения антагонистами pd-l1
|
|
CN116327953A
(zh)
|
2015-06-17 |
2023-06-27 |
豪夫迈·罗氏有限公司 |
使用pd-1轴结合拮抗剂和紫杉烷治疗局部晚期或转移性乳腺癌的方法
|
|
US20190194315A1
(en)
|
2015-06-17 |
2019-06-27 |
Novartis Ag |
Antibody drug conjugates
|
|
MX2017016502A
(es)
|
2015-06-29 |
2018-03-12 |
Univ Rockefeller |
Anticuerpos contra cd40 con actividad agonista mejorada.
|
|
BR112017028530A2
(pt)
|
2015-07-02 |
2018-08-28 |
Celgene Corp |
terapia combinada para tratamento de cânceres hematológicos e tumores sólidos
|
|
HK1254645A1
(zh)
|
2015-07-02 |
2019-07-26 |
Otsuka Pharmaceutical Co., Ltd. |
冻乾药物组合物
|
|
GB201511790D0
(en)
|
2015-07-06 |
2015-08-19 |
Iomet Pharma Ltd |
Pharmaceutical compound
|
|
ES2910035T3
(es)
|
2015-07-13 |
2022-05-11 |
Beyondspring Pharmaceuticals Inc |
Composiciones de plinabulina
|
|
RS61532B1
(sr)
|
2015-07-14 |
2021-04-29 |
Bristol Myers Squibb Co |
Postupak lečenja kancera primenom inhibitora imunološke kontrolne tačke; antitelo koje se vezuje za receptor programirane smrti-1 (pd-1) ili ligand programirane smrti-1 (pd-l1)
|
|
JP7032311B2
(ja)
|
2015-07-16 |
2022-03-08 |
バイオエクセル セラピューティクス,インコーポレイテッド |
免疫調節を使用してがんを処置するための新規手法
|
|
BR112018000903A2
(pt)
|
2015-07-16 |
2018-09-11 |
Biokine Therapeutics Ltd. |
composições e métodos para o tratamento de câncer
|
|
AU2016297014B2
(en)
|
2015-07-21 |
2021-06-17 |
Novartis Ag |
Methods for improving the efficacy and expansion of immune cells
|
|
US10399987B2
(en)
|
2015-07-28 |
2019-09-03 |
Bristol-Myer Squibb Company |
TGF beta receptor antagonists
|
|
EP3878465A1
(en)
|
2015-07-29 |
2021-09-15 |
Novartis AG |
Combination therapies comprising antibody molecules to tim-3
|
|
US20180222982A1
(en)
|
2015-07-29 |
2018-08-09 |
Novartis Ag |
Combination therapies comprising antibody molecules to pd-1
|
|
BR112018001640A2
(pt)
|
2015-07-29 |
2018-09-18 |
Novartis Ag |
combinação de antagonista da pd-1 com um inibidor de egfr
|
|
HRP20211058T8
(hr)
|
2015-07-29 |
2021-11-26 |
Novartis Ag |
Kombinirane terapije koje sadrže molekule antitijela protiv lag-3
|
|
KR102761886B1
(ko)
|
2015-07-30 |
2025-02-06 |
마크로제닉스, 인크. |
Pd-1-결합 분자 및 그것의 사용 방법
|
|
CN106397592A
(zh)
*
|
2015-07-31 |
2017-02-15 |
苏州康宁杰瑞生物科技有限公司 |
针对程序性死亡配体(pd-l1)的单域抗体及其衍生蛋白
|
|
WO2017020291A1
(en)
|
2015-08-06 |
2017-02-09 |
Wuxi Biologics (Shanghai) Co. Ltd. |
Novel anti-pd-l1 antibodies
|
|
WO2017025498A1
(en)
|
2015-08-07 |
2017-02-16 |
Pieris Pharmaceuticals Gmbh |
Novel fusion polypeptide specific for lag-3 and pd-1
|
|
WO2017025871A1
(en)
|
2015-08-07 |
2017-02-16 |
Glaxosmithkline Intellectual Property Development Limited |
Combination therapy comprising anti ctla-4 antibodies
|
|
PL3334763T3
(pl)
|
2015-08-11 |
2024-12-02 |
WuXi Biologics Ireland Limited |
Nowe przeciwciała anty-pd-1
|
|
US11453697B1
(en)
|
2015-08-13 |
2022-09-27 |
Merck Sharp & Dohme Llc |
Cyclic di-nucleotide compounds as sting agonists
|
|
CN108137641B
(zh)
|
2015-08-13 |
2022-04-01 |
默沙东公司 |
作为sting激动剂的环状双核苷酸化合物
|
|
AR105654A1
(es)
|
2015-08-24 |
2017-10-25 |
Lilly Co Eli |
Anticuerpos pd-l1 (ligando 1 de muerte celular programada)
|
|
KR20180042370A
(ko)
|
2015-08-25 |
2018-04-25 |
브리스톨-마이어스 스큅 컴퍼니 |
Tgf 베타 수용체 길항제
|
|
US11385231B2
(en)
|
2015-08-27 |
2022-07-12 |
Inserm (Institut National De La Sante Et De La Recherche Scientifique) |
Methods for predicting the survival time of patients suffering from a lung cancer
|
|
CN108348571B
(zh)
|
2015-09-03 |
2022-03-22 |
艾瑞朗医疗公司 |
拟肽大环化合物及其用途
|
|
JP6156604B1
(ja)
*
|
2015-09-03 |
2017-07-05 |
小野薬品工業株式会社 |
Allergin−1アンタゴニストによるがん免疫増強剤
|
|
WO2017040930A2
(en)
|
2015-09-03 |
2017-03-09 |
The Trustees Of The University Of Pennsylvania |
Biomarkers predictive of cytokine release syndrome
|
|
CN114230571B
(zh)
|
2015-09-14 |
2025-07-08 |
无限药品股份有限公司 |
异喹啉酮的固体形式、其制备方法、包含其的组合物及其使用方法
|
|
MA44909A
(fr)
|
2015-09-15 |
2018-07-25 |
Acerta Pharma Bv |
Association thérapeutique d'un inhibiteur du cd19 et d'un inhibiteur de la btk
|
|
WO2017055322A1
(en)
|
2015-09-29 |
2017-04-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for quantifying the population of neutrophils in a tissue sample
|
|
WO2017055326A1
(en)
|
2015-09-29 |
2017-04-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for quantifying the population of myeloid dendritic cells in a tissue sample
|
|
ES2839212T3
(es)
|
2015-09-29 |
2021-07-05 |
Inst Nat Sante Rech Med |
Métodos para determinar el estado metabólico de linfomas B
|
|
WO2017055320A1
(en)
|
2015-09-29 |
2017-04-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for quantifying the population of cytotoxic lymphocytes in a tissue sample
|
|
WO2017055325A1
(en)
|
2015-09-29 |
2017-04-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for quantifying the population of nk cells in a tissue sample
|
|
WO2017055324A1
(en)
|
2015-09-29 |
2017-04-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for quantifying the population of cells of monocytic origin in a tissue sample
|
|
WO2017055321A1
(en)
|
2015-09-29 |
2017-04-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for quantifying the population of fibroblasts in a tissue sample
|
|
WO2017055319A1
(en)
|
2015-09-29 |
2017-04-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for quantifying the population of b cells in a tissue sample
|
|
WO2017055327A1
(en)
|
2015-09-29 |
2017-04-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for quantifying the population of endothelial cells in a tissue sample
|
|
JP2018529719A
(ja)
|
2015-09-30 |
2018-10-11 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングMerck Patent Gesellschaft mit beschraenkter Haftung |
Alk陰性がんを処置するためのpd−1系結合アンタゴニストおよびalk阻害剤の組合せ
|
|
WO2017059224A2
(en)
|
2015-10-01 |
2017-04-06 |
Gilead Sciences, Inc. |
Combination of a btk inhibitor and a checkpoint inhibitor for treating cancers
|
|
CN108137699B
(zh)
|
2015-10-02 |
2022-05-27 |
豪夫迈·罗氏有限公司 |
对pd1和tim3特异性的双特异性抗体
|
|
ES2895034T3
(es)
|
2015-10-02 |
2022-02-17 |
Hoffmann La Roche |
Anticuerpos anti-PD1 y procedimientos de uso
|
|
WO2017059902A1
(en)
|
2015-10-07 |
2017-04-13 |
Biontech Rna Pharmaceuticals Gmbh |
3' utr sequences for stabilization of rna
|
|
US11174315B2
(en)
|
2015-10-08 |
2021-11-16 |
Macrogenics, Inc. |
Combination therapy for the treatment of cancer
|
|
WO2017060397A1
(en)
|
2015-10-09 |
2017-04-13 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting the survival time of subjects suffering from melanoma metastases
|
|
WO2017064043A1
(en)
|
2015-10-12 |
2017-04-20 |
Innate Pharma |
Cd73 blocking agents
|
|
CN108135934B
(zh)
|
2015-10-19 |
2024-09-10 |
永恒生物科技股份有限公司 |
通过组合疗法治疗实体或淋巴肿瘤的方法
|
|
US10149887B2
(en)
|
2015-10-23 |
2018-12-11 |
Canbas Co., Ltd. |
Peptides and peptidomimetics in combination with t cell activating and/or checkpoint inhibiting agents for cancer treatment
|
|
MA44334A
(fr)
|
2015-10-29 |
2018-09-05 |
Novartis Ag |
Conjugués d'anticorps comprenant un agoniste du récepteur de type toll
|
|
DK3370768T3
(da)
|
2015-11-03 |
2022-03-21 |
Janssen Biotech Inc |
Antistoffer som specifikt binder pd-1 og anvendelser deraf
|
|
WO2017077382A1
(en)
|
2015-11-06 |
2017-05-11 |
Orionis Biosciences Nv |
Bi-functional chimeric proteins and uses thereof
|
|
WO2017087280A1
(en)
|
2015-11-16 |
2017-05-26 |
Genentech, Inc. |
Methods of treating her2-positive cancer
|
|
EP3378871A4
(en)
*
|
2015-11-17 |
2019-08-07 |
Suzhou Suncadia Biopharmaceuticals Co., Ltd. |
PD-L1 ANTIBODY, ANTIGEN FRAGMENT FOR BINDING THEREOF AND PHARMACEUTICAL USE THEREOF
|
|
EP3377534B1
(en)
|
2015-11-18 |
2025-06-18 |
Bristol-Myers Squibb Company |
Treatment of lung cancer using a combination of an anti-pd-1 antibody and an anti-ctla-4 antibody
|
|
CA3004748C
(en)
|
2015-11-18 |
2021-11-16 |
Merck Sharp & Dohme Corp. |
Pd1 and/or lag3 binders
|
|
EP3377532B1
(en)
|
2015-11-19 |
2022-07-27 |
Bristol-Myers Squibb Company |
Antibodies against glucocorticoid-induced tumor necrosis factor receptor (gitr) and uses thereof
|
|
JP6952691B2
(ja)
|
2015-11-19 |
2021-10-20 |
ジェネンテック, インコーポレイテッド |
B−raf阻害剤及び免疫チェックポイント阻害剤を使用してがんを治療する方法
|
|
ES2913208T3
(es)
|
2015-12-01 |
2022-06-01 |
Glaxosmithkline Ip Dev Ltd |
Tratamientos de combinación y usos y métodos de los mismos
|
|
RU2020113165A
(ru)
|
2015-12-03 |
2020-06-09 |
Глэксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед |
Циклические пуриновые динуклеотиды в качестве модуляторов sting
|
|
WO2017098421A1
(en)
|
2015-12-08 |
2017-06-15 |
Glaxosmithkline Intellectual Property Development Limited |
Benzothiadiazine compounds
|
|
EP3178848A1
(en)
|
2015-12-09 |
2017-06-14 |
F. Hoffmann-La Roche AG |
Type ii anti-cd20 antibody for reducing formation of anti-drug antibodies
|
|
PL3387015T3
(pl)
|
2015-12-09 |
2022-02-14 |
F. Hoffmann-La Roche Ag |
Przeciwciało anty-CD20 typu II do ograniczania tworzenia przeciwciał przeciwlekowych
|
|
MA44082A
(fr)
|
2015-12-14 |
2018-10-24 |
Macrogenics Inc |
Molécules bispécifiques présentant une immunoréactivité par rapport à pd-1 et à ctla-4 et leurs procédés d'utilisation
|
|
LT3389699T
(lt)
|
2015-12-15 |
2024-06-10 |
OncoC4, Inc. |
Chimeriniai ir humanizuoti monokloniniai antikūnai prieš žmogaus ctla4 ir jų panaudojimas
|
|
WO2017106062A1
(en)
|
2015-12-15 |
2017-06-22 |
Merck Sharp & Dohme Corp. |
Novel compounds as indoleamine 2,3-dioxygenase inhibitors
|
|
US10450318B2
(en)
|
2015-12-15 |
2019-10-22 |
Bristol-Myers Squibb Company |
CXCR4 receptor antagonists
|
|
GB201522309D0
(en)
|
2015-12-17 |
2016-02-03 |
Photocure Asa |
Use
|
|
MA44075A
(fr)
|
2015-12-17 |
2021-05-19 |
Incyte Corp |
Dérivés de n-phényl-pyridine-2-carboxamide et leur utilisation en tant que modulateurs des interactions protéine/protéine pd-1/pd-l1
|
|
US10392442B2
(en)
|
2015-12-17 |
2019-08-27 |
Bristol-Myers Squibb Company |
Use of anti-PD-1 antibody in combination with anti-CD27 antibody in cancer treatment
|
|
BR112018012138A2
(pt)
|
2015-12-17 |
2018-12-04 |
Novartis Ag |
moléculas de anticorpo para pd-1 e usos das mesmas
|
|
WO2017106453A1
(en)
|
2015-12-17 |
2017-06-22 |
University Of Maryland, Baltimore County |
A recombinant bi-specific polypeptide for coordinately activating tumor-reactive t-cells and neutralizing immune suppression
|
|
UY37030A
(es)
|
2015-12-18 |
2017-07-31 |
Novartis Ag |
Anticuerpos dirigidos a cd32b y métodos de uso de los mismos
|
|
EP3389720A1
(en)
|
2015-12-18 |
2018-10-24 |
The General Hospital Corporation |
Polyacetal polymers, conjugates, particles and uses thereof
|
|
AU2016377371A1
(en)
|
2015-12-21 |
2018-08-09 |
Bristol-Myers Squibb Company |
Variant antibodies for site-specific conjugation
|
|
BR112018012801B1
(pt)
|
2015-12-22 |
2024-03-12 |
Regeneron Pharmaceuticals, Inc |
Usos de uma combinação de anticorpos anti-pd-1 e anticorpos biespecíficos anti-cd20/anti-cd3 e de uma composição farmacêutica
|
|
EP4643874A2
(en)
|
2015-12-22 |
2025-11-05 |
Novartis AG |
Mesothelin chimeric antigen receptor (car) and antibody against pd-l1 inhibitor for combined use in anticancer therapy
|
|
ES2844374T3
(es)
|
2015-12-22 |
2021-07-22 |
Incyte Corp |
Compuestos heterocíclicos como inmunomoduladores
|
|
PT3394093T
(pt)
|
2015-12-23 |
2022-05-30 |
Modernatx Inc |
Métodos de utilização de polinucleotídeos que codificam ligandos ox40
|
|
CN105461808B
(zh)
*
|
2015-12-24 |
2019-03-19 |
长春金赛药业股份有限公司 |
单克隆抗体及其应用
|
|
WO2017118634A1
(en)
|
2016-01-04 |
2017-07-13 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of pd-1 and tim-3 as a measure for cd8+ cells in predicting and treating renal cell carcinoma
|
|
CN106939047B
(zh)
|
2016-01-04 |
2021-08-31 |
江苏怀瑜药业有限公司 |
一种pd-l1抗体及其制备方法
|
|
CN106943596A
(zh)
|
2016-01-07 |
2017-07-14 |
博笛生物科技(北京)有限公司 |
用于治疗肿瘤的抗-cd20组合
|
|
CN106943598A
(zh)
|
2016-01-07 |
2017-07-14 |
博笛生物科技(北京)有限公司 |
用于治疗肿瘤的抗-her2组合
|
|
CN115252792A
(zh)
|
2016-01-07 |
2022-11-01 |
博笛生物科技有限公司 |
用于治疗肿瘤的抗-egfr组合
|
|
HRP20201789T1
(hr)
|
2016-01-08 |
2021-01-22 |
Celgene Corporation |
Antiproliferativni spojevi, te njihovi farmaceutski pripravci i uporabe
|
|
JP6949030B2
(ja)
|
2016-01-08 |
2021-10-13 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
Pd−1軸結合アンタゴニスト及び抗cea/抗cd3二重特異性抗体を用いたcea陽性がんの治療方法
|
|
EP3399979B9
(en)
|
2016-01-08 |
2023-10-04 |
Celgene Corporation |
Formulations of 2-(4-chlorophenyl)-n-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)methyl)-2,2-difluoroacetamide
|
|
ES2959267T3
(es)
|
2016-01-08 |
2024-02-22 |
Celgene Corp |
Formas sólidas de 2-(4-clorofenil)-n-((2-2,6-dioxopiperidin-3-il)-1-oxoisoindolin-5-il)metil)-2,2-difluoroacetamida y sus composiciones farmacéuticas y usos
|
|
HUE052893T2
(hu)
|
2016-01-13 |
2021-05-28 |
Acerta Pharma Bv |
Antifolát és BTK-gátló terápiás kombinációi
|
|
SI3405495T1
(sl)
|
2016-01-21 |
2021-08-31 |
Innate Pharma |
Nevtralizacija inhibitornih poti v limfocitih
|
|
FI3964529T3
(fi)
*
|
2016-01-22 |
2025-06-13 |
MabQuest SA |
Ei-estäviä PD1-spesifisiä vasta-aineita
|
|
MA43660A
(fr)
|
2016-01-22 |
2018-11-28 |
Adimab Llc |
Anticorps anti-facteur xi de coagulation
|
|
ES2924741T3
(es)
|
2016-01-28 |
2022-10-10 |
Inst Nat Sante Rech Med |
Métodos para incrementar la potencia de los inhibidores del punto de control inmunitario
|
|
ES2924775T3
(es)
|
2016-01-28 |
2022-10-10 |
Inst Nat Sante Rech Med |
Métodos y composición farmacéutica para el tratamiento del cáncer
|
|
WO2017129763A1
(en)
|
2016-01-28 |
2017-08-03 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for the treatment of signet ring cell gastric cancer
|
|
CA3013558C
(en)
|
2016-02-05 |
2024-11-12 |
Universiteit Gent |
CD8 LIAISON OFFICERS
|
|
KR102185867B1
(ko)
|
2016-02-06 |
2020-12-02 |
에피맙 바이오테라퓨틱스 인코포레이티드 |
Fabs-인-탠덤 면역글로불린 및 이의 용도
|
|
CN108778267A
(zh)
|
2016-02-08 |
2018-11-09 |
万春药业公司 |
包含妥卡雷琐或其类似物的组合物
|
|
EA038098B1
(ru)
|
2016-02-19 |
2021-07-06 |
Новартис Аг |
Тетрациклические пиридоновые соединения в качестве противовирусных средств
|
|
MX2018010295A
(es)
|
2016-02-26 |
2019-06-06 |
Inst Nat Sante Rech Med |
Anticuerpos que tienen especificidad para atenuador de linfocitos b y t (btla) y usos de los mismos.
|
|
MX2018010361A
(es)
|
2016-02-29 |
2019-07-08 |
Genentech Inc |
Métodos terapéuticos y de diagnóstico para el cáncer.
|
|
JP2019509282A
(ja)
|
2016-02-29 |
2019-04-04 |
ファウンデーション・メディシン・インコーポレイテッド |
癌の治療方法
|
|
JP2019514844A
(ja)
|
2016-03-04 |
2019-06-06 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
抗cd73抗体を用いた併用療法
|
|
US10143746B2
(en)
|
2016-03-04 |
2018-12-04 |
Bristol-Myers Squibb Company |
Immunomodulators
|
|
KR20180118175A
(ko)
|
2016-03-04 |
2018-10-30 |
노파르티스 아게 |
다중 키메라 항원 수용체 (car) 분자를 발현하는 세포 및 그에 따른 용도
|
|
WO2017148424A1
(zh)
*
|
2016-03-04 |
2017-09-08 |
四川科伦博泰生物医药股份有限公司 |
一种pdl-1抗体、其药物组合物及其用途
|
|
US20170252417A1
(en)
|
2016-03-07 |
2017-09-07 |
Massachusetts Institute Of Technology |
Protein-chaperoned t-cell vaccines
|
|
AU2017230850B2
(en)
|
2016-03-08 |
2024-04-18 |
Innate Pharma |
Siglec neutralizing antibodies
|
|
JP7208492B2
(ja)
|
2016-03-10 |
2023-01-19 |
シージー オンコロジー, インコーポレイテッド |
併用療法によって固形腫瘍又はリンパ系腫瘍を処置する方法
|
|
WO2017153952A1
(en)
|
2016-03-10 |
2017-09-14 |
Glaxosmithkline Intellectual Property Development Limited |
5-sulfamoyl-2-hydroxybenzamide derivatives
|
|
WO2017160599A1
(en)
|
2016-03-14 |
2017-09-21 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Use of cd300b antagonists to treat sepsis and septic shock
|
|
US11767362B1
(en)
|
2016-03-15 |
2023-09-26 |
Chugai Seiyaku Kabushiki Kaisha |
Methods of treating cancers using PD-1 axis binding antagonists and anti-GPC3 antibodies
|
|
AU2017234163B2
(en)
|
2016-03-15 |
2023-01-19 |
Mersana Therapeutics, Inc. |
NaPi2b-targeted antibody-drug conjugates and methods of use thereof
|
|
WO2017161976A1
(en)
*
|
2016-03-23 |
2017-09-28 |
Mabspace Biosciences (Suzhou) Co., Ltd |
Novel anti-pd-l1 antibodies
|
|
US11549099B2
(en)
|
2016-03-23 |
2023-01-10 |
Novartis Ag |
Cell secreted minibodies and uses thereof
|
|
MA44483A
(fr)
|
2016-03-24 |
2019-01-30 |
Millennium Pharm Inc |
Procédés pour traiter des événements indésirables gastro-intestinaux d'origine immunitaire dans des traitements oncologiques immunitaires
|
|
WO2017163186A1
(en)
|
2016-03-24 |
2017-09-28 |
Novartis Ag |
Alkynyl nucleoside analogs as inhibitors of human rhinovirus
|
|
WO2017165742A1
(en)
|
2016-03-24 |
2017-09-28 |
Millennium Pharmaceuticals, Inc. |
Methods of treating gastrointestinal immune-related adverse events in anti-ctla4 anti-pd-1 combination treatments
|
|
US11542332B2
(en)
|
2016-03-26 |
2023-01-03 |
Bioatla, Inc. |
Anti-CTLA4 antibodies, antibody fragments, their immunoconjugates and uses thereof
|
|
KR102584300B1
(ko)
|
2016-03-29 |
2023-10-05 |
유니버시티 오브 써던 캘리포니아 |
암을 표적하는 키메라 항원 수용체
|
|
WO2017167921A1
(en)
|
2016-03-30 |
2017-10-05 |
Centre Léon-Bérard |
Lymphocytes expressing cd73 in cancerous patient dictates therapy
|
|
WO2017173334A1
(en)
|
2016-04-01 |
2017-10-05 |
Checkmate Pharmaceuticals, Inc. |
Fc receptor-mediated drug delivery
|
|
WO2017176925A1
(en)
|
2016-04-05 |
2017-10-12 |
Bristol-Myers Squibb Company |
Cytokine profiling analysis for predicting prognosis of a patient in need of an anti-cancer treatment
|
|
US10358463B2
(en)
|
2016-04-05 |
2019-07-23 |
Bristol-Myers Squibb Company |
Immunomodulators
|
|
MX2018012266A
(es)
|
2016-04-07 |
2019-05-30 |
Glaxosmithkline Ip Dev Ltd |
Amidas heterociclicas como moduladores de proteinas.
|
|
HUE058932T2
(hu)
|
2016-04-07 |
2022-09-28 |
Glaxosmithkline Ip Dev Ltd |
Fehérjemodulátorokként hasznos heterociklikus amidok
|
|
EP3440113A1
(en)
|
2016-04-08 |
2019-02-13 |
Gilead Sciences, Inc. |
Compositions and methods for treating cancer, inflammatory diseases and autoimmune diseases
|
|
KR102418765B1
(ko)
|
2016-04-12 |
2022-07-08 |
일라이 릴리 앤드 캄파니 |
암 치료를 위한 Notch 및 CDK4/6 억제제의 조합 요법
|
|
US11564929B2
(en)
|
2016-04-12 |
2023-01-31 |
Eli Lilly And Company |
Combination therapy with Notch and PI3K/mTOR inhibitors for use in treating cancer
|
|
IL295538B2
(en)
|
2016-04-13 |
2024-02-01 |
Vivia Biotech Sl |
In vitro bite-activated T cells
|
|
WO2017180713A1
(en)
|
2016-04-13 |
2017-10-19 |
Orimabs Ltd. |
Anti-psma antibodies and use thereof
|
|
MX2018012434A
(es)
|
2016-04-14 |
2019-06-06 |
Ose Immunotherapeutics |
Nuevos anticuerpos anti-sirpa y sus aplicaciones terapeuticas.
|
|
WO2017181111A2
(en)
|
2016-04-15 |
2017-10-19 |
Genentech, Inc. |
Methods for monitoring and treating cancer
|
|
AU2017248766A1
(en)
|
2016-04-15 |
2018-11-01 |
Genentech, Inc. |
Methods for monitoring and treating cancer
|
|
US12297266B2
(en)
|
2016-04-18 |
2025-05-13 |
Celldex Therapeutics, Inc. |
Agonistic antibodies that bind human CD40 and uses thereof
|
|
WO2017188350A1
(ja)
|
2016-04-28 |
2017-11-02 |
エーザイ・アール・アンド・ディー・マネジメント株式会社 |
腫瘍の成長を抑制する方法
|
|
PL3448364T3
(pl)
|
2016-04-29 |
2022-08-16 |
Icahn School Of Medicine At Mount Sinai |
Celowanie we wrodzony układ immunologiczny dla wywołania długotrwałej tolerancji i wyeliminowania akumulacji makrofagów w miażdżycy naczyń
|
|
US10544099B2
(en)
|
2016-05-04 |
2020-01-28 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
|
WO2017192813A1
(en)
|
2016-05-04 |
2017-11-09 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
|
JP2019516682A
(ja)
|
2016-05-04 |
2019-06-20 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
インドールアミン2,3−ジオキシゲナーゼ阻害剤およびその使用方法
|
|
WO2017192874A1
(en)
|
2016-05-04 |
2017-11-09 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Albumin-binding immunomodulatory compositions and methods of use thereof
|
|
KR20190003685A
(ko)
|
2016-05-04 |
2019-01-09 |
브리스톨-마이어스 스큅 컴퍼니 |
인돌아민 2,3-디옥시게나제의 억제제 및 그의 사용 방법
|
|
EP3452452A4
(en)
|
2016-05-04 |
2019-10-30 |
Bristol-Myers Squibb Company |
INHIBITORS OF INDOLEAMINE-2,3-DIOXYGENASE AND METHOD FOR THEIR USE
|
|
US10604531B2
(en)
|
2016-05-05 |
2020-03-31 |
Glaxosmithkline Intellectual Property (No.2) Limited |
Enhancer of zeste homolog 2 inhibitors
|
|
JP2019518013A
(ja)
|
2016-05-10 |
2019-06-27 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
安定性が向上したツブリシン類似体の抗体薬物結合体
|
|
EP3243832A1
(en)
|
2016-05-13 |
2017-11-15 |
F. Hoffmann-La Roche AG |
Antigen binding molecules comprising a tnf family ligand trimer and pd1 binding moiety
|
|
TWI755395B
(zh)
|
2016-05-13 |
2022-02-21 |
美商再生元醫藥公司 |
抗-pd-1抗體與輻射治療癌症之組合
|
|
EP3455245A2
(en)
|
2016-05-13 |
2019-03-20 |
Orionis Biosciences NV |
Therapeutic targeting of non-cellular structures
|
|
WO2017194783A1
(en)
|
2016-05-13 |
2017-11-16 |
Orionis Biosciences Nv |
Targeted mutant interferon-beta and uses thereof
|
|
EP4137509A1
(en)
|
2016-05-18 |
2023-02-22 |
ModernaTX, Inc. |
Combinations of mrnas encoding immune modulating polypeptides and uses thereof
|
|
US11414491B2
(en)
|
2016-05-18 |
2022-08-16 |
Mayo Foundation For Medical Education And Research |
Targeting PD-L1 on tumor cells
|
|
SG11201809381XA
(en)
|
2016-05-18 |
2018-12-28 |
Modernatx Inc |
Polynucleotides encoding interleukin-12 (il12) and uses thereof
|
|
US11623958B2
(en)
|
2016-05-20 |
2023-04-11 |
Harpoon Therapeutics, Inc. |
Single chain variable fragment CD3 binding proteins
|
|
KR102463617B1
(ko)
|
2016-05-20 |
2022-11-03 |
일라이 릴리 앤드 캄파니 |
Notch 및 PD-1 또는 PD-L1 억제제를 이용한 조합 요법
|
|
CN109890387B
(zh)
|
2016-05-20 |
2022-06-14 |
拜尔哈文制药股份有限公司 |
谷氨酸调节剂与免疫疗法用以治疗癌症的用途
|
|
CN105968200B
(zh)
*
|
2016-05-20 |
2019-03-15 |
瑞阳(苏州)生物科技有限公司 |
抗人pd-l1人源化单克隆抗体及其应用
|
|
MA45122A
(fr)
|
2016-05-24 |
2019-04-10 |
Constellation Pharmaceuticals Inc |
Inhibiteurs hétérocycliques de cbp/ep300 et leur utilisation dans le traitement du cancer
|
|
EP3463452A1
(en)
|
2016-05-24 |
2019-04-10 |
Institut National de la Sante et de la Recherche Medicale (INSERM) |
Methods and pharmaceutical compositions for the treatment of non small cell lung cancer (nsclc) that coexists with chronic obstructive pulmonary disease (copd)
|
|
CN109476663B
(zh)
|
2016-05-24 |
2021-11-09 |
基因泰克公司 |
用于治疗癌症的吡唑并吡啶衍生物
|
|
CN116376812A
(zh)
|
2016-05-25 |
2023-07-04 |
国家医疗保健研究所 |
治疗癌症的方法和组合物
|
|
TWI781934B
(zh)
|
2016-05-27 |
2022-11-01 |
美商艾吉納斯公司 |
抗-tim-3抗體及其使用方法
|
|
US10994033B2
(en)
|
2016-06-01 |
2021-05-04 |
Bristol-Myers Squibb Company |
Imaging methods using 18F-radiolabeled biologics
|
|
WO2017210302A1
(en)
|
2016-06-01 |
2017-12-07 |
Bristol-Myers Squibb Company |
Pet imaging with pd-l1 binding polypeptides
|
|
DK3463457T3
(da)
|
2016-06-02 |
2023-10-02 |
Bristol Myers Squibb Co |
Pd-1-blokade med nivolumab ved refraktært hodgkins lymfom
|
|
EP3252078A1
(en)
|
2016-06-02 |
2017-12-06 |
F. Hoffmann-La Roche AG |
Type ii anti-cd20 antibody and anti-cd20/cd3 bispecific antibody for treatment of cancer
|
|
FI3464368T3
(fi)
|
2016-06-02 |
2023-09-12 |
Bristol Myers Squibb Co |
Anti-pd-1-vasta-aineen käyttö yhdistelmänä anti-cd30-vasta-aineen kanssa lymfooman hoitamisessa
|
|
TW201902512A
(zh)
|
2016-06-02 |
2019-01-16 |
瑞士商赫孚孟拉羅股份公司 |
治療方法
|
|
RS65007B1
(sr)
|
2016-06-02 |
2024-01-31 |
Ultimovacs Asa |
Vakcina u kombinaciji sa inhibitorom imunološke kontrolne tačke za primenu u lečenju kancera
|
|
JP2019517498A
(ja)
|
2016-06-03 |
2019-06-24 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
再発性小細胞肺癌の処置方法において使用するための抗pd−1抗体
|
|
WO2017210637A1
(en)
|
2016-06-03 |
2017-12-07 |
Bristol-Myers Squibb Company |
Use of anti-pd-1 antibody in the treatment of patients with colorectal cancer
|
|
WO2017210624A1
(en)
|
2016-06-03 |
2017-12-07 |
Bristol-Myers Squibb Company |
Anti-pd-1 antibody for use in a method of treating a tumor
|
|
RU2760348C2
(ru)
|
2016-06-06 |
2021-11-24 |
Бейондспринг Фармасьютикалс, Инк. |
Способ уменьшения нейтропении
|
|
WO2017212423A1
(en)
|
2016-06-08 |
2017-12-14 |
Glaxosmithkline Intellectual Property Development Limited |
Chemcical compounds
|
|
AU2017279029A1
(en)
|
2016-06-08 |
2018-12-20 |
Glaxosmithkline Intellectual Property Development Limited |
Chemical compounds as ATF4 pathway inhibitors
|
|
PE20190510A1
(es)
*
|
2016-06-13 |
2019-04-10 |
I Mab |
Anticuerpos anti-pd-l1 y usos de los mismos
|
|
CN109715196A
(zh)
|
2016-06-13 |
2019-05-03 |
转矩医疗股份有限公司 |
用于促进免疫细胞功能的组合物和方法
|
|
CN107488229B
(zh)
*
|
2016-06-13 |
2020-11-17 |
天境生物科技(上海)有限公司 |
Pd-l1抗体及其用途
|
|
GEAP202114983A
(en)
|
2016-06-14 |
2021-12-10 |
Merck Sharp & Dohme Corp |
Anti-coagulation factor xi antibodies
|
|
PL3468957T3
(pl)
|
2016-06-14 |
2021-01-25 |
Novartis Ag |
Krystaliczna postać (r)-4-(5-(cyklopropyloetynylo)izoksa-zol-3- ilo)- n-hydroksy-2-metylo-2-(metylosulfonylo)butano-amidu jako środek przeciwbakteryjny
|
|
WO2017216685A1
(en)
|
2016-06-16 |
2017-12-21 |
Novartis Ag |
Pentacyclic pyridone compounds as antivirals
|
|
WO2017216686A1
(en)
|
2016-06-16 |
2017-12-21 |
Novartis Ag |
8,9-fused 2-oxo-6,7-dihydropyrido-isoquinoline compounds as antivirals
|
|
US9567399B1
(en)
|
2016-06-20 |
2017-02-14 |
Kymab Limited |
Antibodies and immunocytokines
|
|
TW201803905A
(zh)
|
2016-06-20 |
2018-02-01 |
克馬伯有限公司 |
用於免疫腫瘤學之多重專一性抗體
|
|
PL3472207T3
(pl)
*
|
2016-06-20 |
2021-07-12 |
F-Star Delta Limited |
Wiążące cząsteczki wiążące się z PD-L1 i LAG-3
|
|
HUE060256T2
(hu)
|
2016-06-20 |
2023-02-28 |
Incyte Corp |
Heterociklusos vegyületek mint immunmodulátorok
|
|
WO2018029474A2
(en)
|
2016-08-09 |
2018-02-15 |
Kymab Limited |
Anti-icos antibodies
|
|
JP7085708B2
(ja)
|
2016-06-20 |
2022-06-17 |
エフ-スター セラピューティクス リミテッド |
Lag-3結合要素
|
|
JP7267014B2
(ja)
|
2016-06-21 |
2023-05-01 |
アイオー バイオテック エーピーエス |
癌ワクチンにおける使用のためのpdl1ペプチド
|
|
US11147818B2
(en)
|
2016-06-24 |
2021-10-19 |
Infinity Pharmaceuticals, Inc. |
Combination therapies
|
|
IL276515B2
(en)
|
2016-06-29 |
2025-11-01 |
Checkpoint Therapeutics Inc |
Pd-l1-specific antibodies and methods of using the same
|
|
RU2021127872A
(ru)
|
2016-06-30 |
2021-11-09 |
Онкорус, Инк. |
Доставка терапевтических полипептидов посредством псевдотипированных онколитических вирусов
|
|
EP3507367A4
(en)
|
2016-07-05 |
2020-03-25 |
Aduro BioTech, Inc. |
CYCLIC DINUCLEOTID COMPOUNDS WITH INCLUDED NUCLEIC ACIDS AND USES THEREOF
|
|
CN109475536B
(zh)
|
2016-07-05 |
2022-05-27 |
百济神州有限公司 |
用于治疗癌症的PD-l拮抗剂和RAF抑制剂的组合
|
|
EP3481866B1
(en)
|
2016-07-06 |
2024-07-24 |
Bristol-Myers Squibb Company |
Combination of tim-4 antagonist and pd-1 antagonist and methods of use
|
|
ES3000676T3
(en)
|
2016-07-07 |
2025-03-03 |
Iovance Biotherapeutics Inc |
Programmed death 1 ligand 1 (pd-l1) binding proteins and methods of use thereof
|
|
WO2018011166A2
(en)
|
2016-07-12 |
2018-01-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for quantifying the population of myeloid dendritic cells in a tissue sample
|
|
US20190248893A1
(en)
|
2016-07-14 |
2019-08-15 |
Bristol-Myers Squibb Company |
Antibodies against tim3 and uses thereof
|
|
GB201612520D0
(en)
|
2016-07-19 |
2016-08-31 |
F-Star Beta Ltd |
Binding molecules
|
|
CA3031542A1
(en)
|
2016-07-20 |
2018-01-25 |
University Of Utah Research Foundation |
Cd229 car t cells and methods of use thereof
|
|
CA3031047A1
(en)
|
2016-07-20 |
2018-01-25 |
Glaxosmithkline Intellectual Property Development Limited |
Isoquinoline derivatives as perk inhibitors
|
|
WO2018017633A1
(en)
|
2016-07-21 |
2018-01-25 |
Bristol-Myers Squibb Company |
TGF Beta RECEPTOR ANTAGONISTS
|
|
CN109562282A
(zh)
|
2016-07-29 |
2019-04-02 |
伊莱利利公司 |
用于治疗癌症的使用merestinib和抗-pd-l1或抗-pd-1抑制剂的组合疗法
|
|
EP3490548A4
(en)
|
2016-08-01 |
2020-04-15 |
Molecular Templates, Inc. |
ADMINISTRATION OF HYPOXIA-ACTIVATED DRUGS IN COMBINATION WITH IMMUNOMODULATORS FOR THE TREATMENT OF CANCER
|
|
AU2017306560B2
(en)
|
2016-08-03 |
2024-08-22 |
Nextcure, Inc. |
Compositions and methods for modulating lair signal transduction
|
|
WO2018026249A1
(ko)
*
|
2016-08-05 |
2018-02-08 |
주식회사 와이바이오로직스 |
프로그램화된 세포 사멸 단백질 리간드-1 (pd-l1)에 대한 항체 및 이의 용도
|
|
RU2721582C1
(ru)
*
|
2016-08-05 |
2020-05-20 |
И-Байолоджикс Инк. |
Антитела против лиганда-1 запрограммированной смерти (PD-L1) и их применение
|
|
JP2019530434A
(ja)
|
2016-08-05 |
2019-10-24 |
ジェネンテック, インコーポレイテッド |
アゴニスト活性を有する多価及び多重エピトープ抗体ならびに使用方法
|
|
EP3497129A1
(en)
|
2016-08-08 |
2019-06-19 |
H. Hoffnabb-La Roche Ag |
Therapeutic and diagnostic methods for cancer
|
|
KR102604433B1
(ko)
|
2016-08-09 |
2023-11-24 |
키맵 리미티드 |
항-icos 항체
|
|
MX386014B
(es)
|
2016-08-10 |
2025-03-18 |
Univ Ajou Ind Academic Coop Found |
Citocina fusionada a fc heterodimérico, y composición farmacéutica que comprende la misma.
|
|
WO2018029336A1
(en)
|
2016-08-12 |
2018-02-15 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for determining whether a subject was administered with an activator of the ppar beta/delta pathway.
|
|
AU2017311585A1
(en)
|
2016-08-12 |
2019-02-28 |
Genentech, Inc. |
Combination therapy with a MEK inhibitor, a PD-1 axis inhibitor, and a VEGF inhibitor
|
|
US20180118832A1
(en)
|
2016-08-12 |
2018-05-03 |
Merck Patent Gmbh |
Combination therapy for cancer
|
|
KR102569068B1
(ko)
|
2016-08-15 |
2023-08-21 |
국립대학법인 홋가이도 다이가쿠 |
항pd-l1 항체
|
|
FI3500299T3
(fi)
|
2016-08-19 |
2024-02-14 |
Beigene Switzerland Gmbh |
Tsanubrutinibin yhdistelmä cd20-tai pd-1-vasta-aineen kanssa käytettäväksi syövän hoidossa
|
|
KR102493853B1
(ko)
|
2016-08-19 |
2023-01-30 |
브리스톨-마이어스 스큅 컴퍼니 |
세코-시클로프로파피롤로인돌 화합물, 그의 항체-약물 접합체, 및 제조 및 사용 방법
|
|
EP3500294A4
(en)
|
2016-08-22 |
2020-07-29 |
Arbutus Biopharma Corporation |
ANTI-PD-1 ANTIBODIES, OR THEIR FRAGMENTS, FOR THE TREATMENT OF HEPATITIS B
|
|
CN109843322A
(zh)
|
2016-08-26 |
2019-06-04 |
百时美施贵宝公司 |
吲哚胺2,3-双加氧酶的抑制剂及其使用方法
|
|
JP7045378B2
(ja)
|
2016-09-01 |
2022-03-31 |
キメラ・バイオエンジニアリング,インコーポレーテッド |
Gold最適化CAR T細胞
|
|
CN106248955A
(zh)
*
|
2016-09-03 |
2016-12-21 |
长春工业大学 |
一种检测人源化pd‑l1抗体的试剂盒
|
|
EP3509604A4
(en)
|
2016-09-07 |
2020-08-26 |
Trustees of Tufts College |
POLYTHERAPIES USING IMMUNO-DASH INHIBITORS AND PGE2 ANTAGONISTS
|
|
US20190218294A1
(en)
|
2016-09-09 |
2019-07-18 |
Bristol-Myers Squibb Company |
Use of an anti-pd-1 antibody in combination with an anti-mesothelin antibody in cancer treatment
|
|
JP2019526595A
(ja)
|
2016-09-09 |
2019-09-19 |
ティージー セラピューティクス,インコーポレイテッド |
血液癌を治療するための抗cd20抗体、pi3キナーゼ−デルタ阻害剤および抗pd−1抗体または抗pd−l1抗体の組み合わせ
|
|
TW201811788A
(zh)
|
2016-09-09 |
2018-04-01 |
瑞士商諾華公司 |
作為抗病毒劑之多環吡啶酮化合物
|
|
WO2018046736A1
(en)
|
2016-09-12 |
2018-03-15 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting the survival time of patients suffering from cancer
|
|
WO2018046738A1
(en)
|
2016-09-12 |
2018-03-15 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting the survival time of patients suffering from cancer
|
|
DK4339615T3
(da)
|
2016-09-16 |
2025-12-22 |
Shanghai Henlius Biotech Inc |
Anti-PD-1-antistof til anvendelse i behandlingen af kræft
|
|
WO2018053434A1
(en)
|
2016-09-16 |
2018-03-22 |
The Johns Hopkins University |
Protein nanocages with enhanced mucus penetration for targeted tissue and intracellular delivery
|
|
AU2017329780B2
(en)
*
|
2016-09-20 |
2024-11-14 |
Merck Patent Gmbh |
Diagnostic anti-PD-L1 antibody and use thereof
|
|
AU2017330346C1
(en)
|
2016-09-21 |
2025-03-06 |
Nextcure, Inc. |
Antibodies for Siglec-15 and methods of use thereof
|
|
EP4360714A3
(en)
|
2016-09-21 |
2024-07-24 |
Nextcure, Inc. |
Antibodies for siglec-15 and methods of use thereof
|
|
US11077178B2
(en)
|
2016-09-21 |
2021-08-03 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Chimeric antigen receptor (CAR) that targets chemokine receptor CCR4 and its use
|
|
WO2018055080A1
(en)
|
2016-09-22 |
2018-03-29 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for reprograming immune environment in a subject in need thereof
|
|
WO2018057955A1
(en)
|
2016-09-23 |
2018-03-29 |
Elstar Therapeutics, Inc. |
Multispecific antibody molecules comprising lambda and kappa light chains
|
|
WO2018055145A1
(en)
|
2016-09-26 |
2018-03-29 |
F. Hoffmann-La Roche Ag |
Predicting response to pd-1 axis inhibitors
|
|
CN109863402A
(zh)
|
2016-09-27 |
2019-06-07 |
鼎航医药股份有限公司 |
基于β2-糖蛋白1水平的用巴维昔单抗治疗癌症的方法和其测定
|
|
JOP20190061A1
(ar)
|
2016-09-28 |
2019-03-26 |
Novartis Ag |
مثبطات بيتا-لاكتاماز
|
|
CN109862917A
(zh)
|
2016-09-29 |
2019-06-07 |
基因泰克公司 |
Mek抑制剂,pd-1轴抑制剂,和紫杉烷的组合疗法
|
|
RS62410B1
(sr)
|
2016-10-04 |
2021-10-29 |
Merck Sharp & Dohme |
Benzo[b]tiofenska jedinjenja kao agonisti sting
|
|
CA3039451A1
(en)
|
2016-10-06 |
2018-04-12 |
Pfizer Inc. |
Dosing regimen of avelumab for the treatment of cancer
|
|
KR102804118B1
(ko)
|
2016-10-06 |
2025-05-09 |
제넨테크, 인크. |
암에 대한 치료 및 진단 방법
|
|
CN110225927B
(zh)
|
2016-10-07 |
2024-01-12 |
诺华股份有限公司 |
用于治疗癌症的嵌合抗原受体
|
|
AU2017342176A1
(en)
|
2016-10-10 |
2019-05-02 |
The National Institute for Biotechnology in the Negev Ltd. |
Non-cytotoxic modified cells and use thereof
|
|
MX2019003683A
(es)
|
2016-10-11 |
2019-08-22 |
Agenus Inc |
Anticuerpos anti gen 3 de activación linfocítica (lag 3 ) y métodos para usarlos.
|
|
EP3525796A1
(en)
|
2016-10-12 |
2019-08-21 |
Eli Lilly and Company |
Targeted treatment of mature t-cell lymphoma
|
|
EP3525818A1
(en)
|
2016-10-14 |
2019-08-21 |
Merck Sharp & Dohme Corp. |
Combination of a pd-1 antagonist and eribulin for treating urothelial cancer
|
|
WO2018071576A1
(en)
|
2016-10-14 |
2018-04-19 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Treatment of tumors by inhibition of cd300f
|
|
WO2018073753A1
(en)
|
2016-10-18 |
2018-04-26 |
Novartis Ag |
Fused tetracyclic pyridone compounds as antivirals
|
|
WO2018075447A1
(en)
|
2016-10-19 |
2018-04-26 |
The Trustees Of Columbia University In The City Of New York |
Combination of braf inhibitor, talimogene laherparepvec, and immune checkpoint inhibitor for use in the treatment cancer (melanoma)
|
|
WO2018075842A1
(en)
|
2016-10-20 |
2018-04-26 |
Bristol-Myers Squibb Company |
Condensed benzodiazepine derivatives and conjugates made therefrom
|
|
WO2018077893A1
(en)
|
2016-10-24 |
2018-05-03 |
Orionis Biosciences Nv |
Targeted mutant interferon-gamma and uses thereof
|
|
KR20240150531A
(ko)
|
2016-10-26 |
2024-10-15 |
이오반스 바이오테라퓨틱스, 인크. |
냉동보존된 종양 침윤 림프구의 재자극
|
|
CN107987153A
(zh)
*
|
2016-10-27 |
2018-05-04 |
广东香雪精准医疗技术有限公司 |
高亲和力的可溶性pd-1分子
|
|
CN106478819B
(zh)
*
|
2016-10-27 |
2018-12-07 |
常州费洛斯药业科技有限公司 |
一种针对pd-l1的单克隆抗体或抗体片段
|
|
JP7258747B2
(ja)
|
2016-10-28 |
2023-04-17 |
ブリストル-マイヤーズ スクイブ カンパニー |
抗pd-1抗体を用いた尿路上皮癌の処置方法
|
|
WO2018081531A2
(en)
|
2016-10-28 |
2018-05-03 |
Ariad Pharmaceuticals, Inc. |
Methods for human t-cell activation
|
|
WO2018081648A2
(en)
|
2016-10-29 |
2018-05-03 |
Genentech, Inc. |
Anti-mic antibidies and methods of use
|
|
WO2018080812A1
(en)
*
|
2016-10-30 |
2018-05-03 |
Henlix, Inc. |
Anti-pd-l1 antibodies and variants
|
|
TWI788307B
(zh)
|
2016-10-31 |
2023-01-01 |
美商艾歐凡斯生物治療公司 |
用於擴增腫瘤浸潤性淋巴細胞之工程化人造抗原呈現細胞
|
|
EP4295918A3
(en)
|
2016-11-02 |
2024-03-20 |
Bristol-Myers Squibb Company |
Bispecific antibody against bcma and cd3 and an immunological drug for combined use in treating multiple myeloma
|
|
EP3534947A1
(en)
|
2016-11-03 |
2019-09-11 |
Kymab Limited |
Antibodies, combinations comprising antibodies, biomarkers, uses & methods
|
|
KR102584340B1
(ko)
|
2016-11-03 |
2023-10-10 |
브리스톨-마이어스 스큅 컴퍼니 |
활성화가능한 항-ctla-4 항체 및 그의 용도
|
|
US10342785B2
(en)
|
2016-11-04 |
2019-07-09 |
Askat Inc. |
Use of EP4 receptor antagonists for the treatment of NASH-associated liver cancer
|
|
EP3535280B1
(en)
|
2016-11-07 |
2022-03-16 |
Bristol-Myers Squibb Company |
Immunomodulators
|
|
EP3538140A1
(en)
|
2016-11-14 |
2019-09-18 |
Institut National de la Sante et de la Recherche Medicale (INSERM) |
Methods and pharmaceutical compositions for modulating stem cells proliferation or differentiation
|
|
WO2018093821A1
(en)
|
2016-11-15 |
2018-05-24 |
Genentech, Inc. |
Dosing for treatment with anti-cd20/anti-cd3 bispecific antibodies
|
|
US10660909B2
(en)
|
2016-11-17 |
2020-05-26 |
Syntrix Biosystems Inc. |
Method for treating cancer using chemokine antagonists
|
|
WO2018094167A1
(en)
|
2016-11-17 |
2018-05-24 |
Iovance Biotherapeutics, Inc. |
Remnant tumor infiltrating lymphocytes and methods of preparing and using the same
|
|
US11279694B2
(en)
|
2016-11-18 |
2022-03-22 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Alvocidib prodrugs and their use as protein kinase inhibitors
|
|
CN106496327B
(zh)
*
|
2016-11-18 |
2019-01-15 |
昆山百尔泰生物科技有限公司 |
针对pd-l1胞外段的人源抗体或抗体片段和用途、核苷酸序列和载体
|
|
EP3541825A1
(en)
|
2016-11-21 |
2019-09-25 |
Idenix Pharmaceuticals LLC. |
Cyclic phosphate substituted nucleoside derivatives for the treatment of liver diseases
|
|
WO2018098352A2
(en)
|
2016-11-22 |
2018-05-31 |
Jun Oishi |
Targeting kras induced immune checkpoint expression
|
|
US11135307B2
(en)
|
2016-11-23 |
2021-10-05 |
Mersana Therapeutics, Inc. |
Peptide-containing linkers for antibody-drug conjugates
|
|
JP7106563B2
(ja)
|
2016-11-29 |
2022-07-26 |
スミトモ ファーマ オンコロジー, インコーポレイテッド |
ナフトフラン誘導体、その調製、および使用方法
|
|
CN110662552A
(zh)
|
2016-11-30 |
2020-01-07 |
昂科梅德制药有限公司 |
包含tigit结合剂的癌症治疗方法
|
|
JP2020511407A
(ja)
|
2016-12-01 |
2020-04-16 |
グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited |
併用療法
|
|
MY191926A
(en)
|
2016-12-01 |
2022-07-18 |
Regeneron Pharma |
Radiolabeled anti-pd-l1 antibodies for immuno-pet imaging
|
|
EP3548069A1
(en)
|
2016-12-01 |
2019-10-09 |
GlaxoSmithKline Intellectual Property Development Limited |
Combination therapy
|
|
WO2018102786A1
(en)
|
2016-12-03 |
2018-06-07 |
Juno Therapeutics, Inc. |
Methods for modulation of car-t cells
|
|
WO2018106738A1
(en)
|
2016-12-05 |
2018-06-14 |
Massachusetts Institute Of Technology |
Brush-arm star polymers, conjugates and particles, and uses thereof
|
|
EP3551645A1
(en)
|
2016-12-07 |
2019-10-16 |
Molecular Templates, Inc. |
Shiga toxin a subunit effector polypeptides, shiga toxin effector scaffolds, and cell-targeting molecules for site-specific conjugation
|
|
AU2017373944B2
(en)
|
2016-12-07 |
2022-02-03 |
Agenus Inc. |
Anti-CTLA-4 antibodies and methods of use thereof
|
|
AU2017373945B2
(en)
|
2016-12-07 |
2025-01-23 |
Agenus Inc. |
Antibodies and methods of use thereof
|
|
DK3551629T3
(da)
|
2016-12-08 |
2024-02-12 |
Lixte Biotechnology Inc |
Oxabicycloheptaner til modulering af immunrespons
|
|
AU2017375946A1
(en)
|
2016-12-12 |
2019-06-20 |
Genentech, Inc. |
Methods of treating cancer using anti-PD-l1 antibodies and antiandrogens
|
|
EP3554561B1
(en)
|
2016-12-14 |
2023-06-28 |
Janssen Biotech, Inc. |
Cd137 binding fibronectin type iii domains
|
|
JP7104703B2
(ja)
|
2016-12-14 |
2022-07-21 |
ヤンセン バイオテツク,インコーポレーテツド |
Cd8a結合フィブロネクチンiii型ドメイン
|
|
WO2018111976A1
(en)
|
2016-12-14 |
2018-06-21 |
Janssen Biotech, Inc. |
Pd-l1 binding fibronectin type iii domains
|
|
US20200095301A1
(en)
|
2016-12-14 |
2020-03-26 |
The Board Of Trustees Of The Leland Stanford Junior University |
Il-13 superkine: immune cell targeting constructs and methods of use thereof
|
|
WO2018112360A1
(en)
|
2016-12-16 |
2018-06-21 |
Evelo Biosciences, Inc. |
Combination therapies for treating cancer
|
|
WO2018112364A1
(en)
|
2016-12-16 |
2018-06-21 |
Evelo Biosciences, Inc. |
Combination therapies for treating melanoma
|
|
CN110526973A
(zh)
*
|
2016-12-21 |
2019-12-03 |
南京金斯瑞生物科技有限公司 |
高亲和力、高特异性、多抗原识别表位的具有更高功能性的抗人ctla4抗体
|
|
GEP20227428B
(en)
|
2016-12-22 |
2022-10-25 |
Incyte Corp |
Heterocyclic compounds as immunomodulators
|
|
WO2018119286A1
(en)
|
2016-12-22 |
2018-06-28 |
Incyte Corporation |
Bicyclic heteroaromatic compounds as immunomodulators
|
|
WO2018115458A1
(en)
|
2016-12-23 |
2018-06-28 |
Virttu Biologics Limited |
Treatment of cancer
|
|
EP3559032A1
(en)
|
2016-12-23 |
2019-10-30 |
Innate Pharma |
Heterodimeric antigen binding proteins
|
|
RU2766582C2
(ru)
*
|
2016-12-23 |
2022-03-15 |
Ремд Биотерапьютикс, Инк. |
Иммунотерапия с применением антител, связывающих лиганд 1 белка программируемой смерти клеток (PD-L1)
|
|
WO2018122249A1
(en)
|
2016-12-28 |
2018-07-05 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting the survival time of patients suffering from a microsatellite stable colorectal cancer
|
|
WO2018122245A1
(en)
|
2016-12-28 |
2018-07-05 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods of predicting the survival time of patients suffering from cms3 colorectal cancer
|
|
US10961239B2
(en)
|
2017-01-05 |
2021-03-30 |
Bristol-Myers Squibb Company |
TGF beta receptor antagonists
|
|
US12162932B2
(en)
|
2017-01-05 |
2024-12-10 |
Netris Pharma |
Combined treatment with Netrin-1 interfering drug and immune checkpoint inhibitors drugs
|
|
JP7664020B2
(ja)
|
2017-01-06 |
2025-04-17 |
アイオバンス バイオセラピューティクス,インコーポレイテッド |
カリウムチャネルアゴニストによる腫瘍浸潤リンパ球の増殖及びその治療的使用
|
|
CN110431135A
(zh)
|
2017-01-06 |
2019-11-08 |
大连万春布林医药有限公司 |
微管蛋白结合化合物及其治疗用途
|
|
US11584733B2
(en)
|
2017-01-09 |
2023-02-21 |
Shuttle Pharmaceuticals, Inc. |
Selective histone deacetylase inhibitors for the treatment of human disease
|
|
ES2914123T3
(es)
|
2017-01-09 |
2022-06-07 |
Shuttle Pharmaceuticals Inc |
Inhibidores selectivos de la histona desacetilasa para el tratamiento de una enfermedad humana
|
|
EP3565560B1
(en)
|
2017-01-09 |
2024-05-29 |
OnkosXcel Therapeutics, LLC |
Predictive and diagnostic methods for prostate cancer
|
|
WO2018132427A1
(en)
|
2017-01-10 |
2018-07-19 |
The General Hospital Corporation |
Targeted t cells with cytotoxicity toward immunosuppressive cells
|
|
JP2020503883A
(ja)
|
2017-01-13 |
2020-02-06 |
アジェナス インコーポレイテッド |
Ny−eso−1に結合するt細胞受容体およびその使用方法
|
|
WO2018134279A1
(en)
|
2017-01-18 |
2018-07-26 |
Pieris Pharmaceuticals Gmbh |
Novel fusion polypeptides specific for lag-3 and pd-1
|
|
HRP20231157T1
(hr)
|
2017-01-20 |
2024-01-05 |
Arcus Biosciences, Inc. |
Azolopirimidin za liječenje poremećaja povezanih s rakom
|
|
EP3573989A4
(en)
|
2017-01-25 |
2020-11-18 |
Beigene, Ltd. |
CRYSTALLINE FORMS OF (S) -7- (1- (BUT-2-YNOYL) PIPERIDIN-4-YL) -2- (4-PHENOXYPHENYL) -4, 5, 6, 7-TETRAHY DROPYRAZOLO [1, 5-A ] PYRIMIDINE-3-CARBOXAMIDE, PREPARATION AND ASSOCIATED USES
|
|
JP7082424B2
(ja)
|
2017-01-25 |
2022-06-08 |
モレキュラー テンプレーツ,インク. |
脱免疫化された志賀毒素aサブユニットエフェクター及びcd8+t細胞エピトープを含む細胞標的化分子
|
|
JP7275031B2
(ja)
|
2017-01-27 |
2023-05-17 |
ヤンセン バイオテツク,インコーポレーテツド |
Stingアゴニストとしての環状ジヌクレオチド
|
|
JP7062010B2
(ja)
|
2017-01-27 |
2022-05-02 |
セルジーン コーポレイション |
3-(1-オキソ-4-((4-((3-オキソモルホリノ)メチル)ベンジル)オキシ)イソインドリン-2-イル)ピペリジン-2,6-ジオン及びそのアイソトポログ
|
|
US11021511B2
(en)
|
2017-01-27 |
2021-06-01 |
Janssen Biotech, Inc. |
Cyclic dinucleotides as sting agonists
|
|
US11400086B2
(en)
|
2017-02-01 |
2022-08-02 |
Beyondspring Pharmaceuticals, Inc. |
Method of reducing chemotherapy-induced neutropenia
|
|
JOP20190187A1
(ar)
|
2017-02-03 |
2019-08-01 |
Novartis Ag |
مترافقات عقار جسم مضاد لـ ccr7
|
|
KR102642385B1
(ko)
|
2017-02-06 |
2024-03-04 |
오리오니스 바이오사이언시스 엔브이 |
표적화된 키메라 단백질 및 이의 용도
|
|
CN110573172A
(zh)
|
2017-02-06 |
2019-12-13 |
奥里尼斯生物科学有限公司 |
靶向的工程化干扰素及其用途
|
|
WO2018141959A1
(en)
|
2017-02-06 |
2018-08-09 |
Innate Pharma |
Immunomodulatory antibody drug conjugates binding to a human mica polypeptide
|
|
WO2018146148A1
(en)
|
2017-02-07 |
2018-08-16 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
A method for predicting the response to checkpoint blockade cancer immunotherapy
|
|
WO2018146128A1
(en)
|
2017-02-07 |
2018-08-16 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Detection of kit polymorphism for predicting the response to checkpoint blockade cancer immunotherapy
|
|
EP3580237B1
(en)
|
2017-02-08 |
2025-05-14 |
Novartis AG |
Fgf21 mimetic antibodies and uses thereof
|
|
JP7161481B2
(ja)
|
2017-02-10 |
2022-10-26 |
ノバルティス アーゲー |
1-(4-アミノ-5-ブロモ-6-(1h-ピラゾール-1-イル)ピリミジン-2-イル)-1h-ピラゾール-4-オール及びがんの治療におけるその使用
|
|
US20200291089A1
(en)
|
2017-02-16 |
2020-09-17 |
Elstar Therapeutics, Inc. |
Multifunctional molecules comprising a trimeric ligand and uses thereof
|
|
US11325976B2
(en)
|
2017-02-16 |
2022-05-10 |
Ying Zhang |
Anti-programmed death-ligand 1 (PD-L1) antibodies and therapeutic uses thereof
|
|
KR20190116420A
(ko)
|
2017-02-17 |
2019-10-14 |
프레드 헛친슨 켄서 리서치 센터 |
Bcma 관련 암 및 자가면역 장애의 치료를 위한 조합 요법
|
|
TWI674261B
(zh)
|
2017-02-17 |
2019-10-11 |
美商英能腫瘤免疫股份有限公司 |
Nlrp3 調節劑
|
|
CN108456251A
(zh)
*
|
2017-02-21 |
2018-08-28 |
上海君实生物医药科技股份有限公司 |
抗pd-l1抗体及其应用
|
|
KR20240011262A
(ko)
|
2017-02-21 |
2024-01-25 |
리제너론 파아마슈티컬스, 인크. |
폐암의 치료를 위한 항-pd-1 항체
|
|
KR102585848B1
(ko)
|
2017-02-24 |
2023-10-11 |
마크로제닉스, 인크. |
Cd137 및 종양 항원에 결합할 수 있는 이중특이적 결합 분자, 및 그것의 용도
|
|
WO2018154529A1
(en)
|
2017-02-27 |
2018-08-30 |
Novartis Ag |
Dosing schedule for a combination of ceritinib and an anti-pd-1 antibody molecule
|
|
US20200062735A1
(en)
|
2017-02-27 |
2020-02-27 |
Glaxosmithkline Intellectual Property Development Limited |
Heterocyclic amides as kinase inhibitors
|
|
EP3366703B1
(en)
|
2017-02-28 |
2019-04-03 |
Ralf Kleef |
Immune checkpoint therapy with hyperthermia
|
|
TW201834697A
(zh)
|
2017-02-28 |
2018-10-01 |
美商梅爾莎納醫療公司 |
Her2標靶抗體-藥物結合物之組合療法
|
|
PL3589754T3
(pl)
|
2017-03-01 |
2023-10-09 |
F. Hoffmann-La Roche Ag |
Sposoby diagnostyczne i terapeutyczne w chorobach nowotworowych
|
|
EP3372615A1
(en)
*
|
2017-03-06 |
2018-09-12 |
Merck Patent GmbH |
Composition comprising avelumab
|
|
EP3592769B1
(en)
|
2017-03-09 |
2024-05-08 |
Genmab A/S |
Antibodies against pd-l1
|
|
DK3595668T3
(da)
|
2017-03-15 |
2021-10-18 |
Silverback Therapeutics Inc |
Benzazepinforbindelser, konjugater og anvendelser deraf
|
|
WO2018167147A1
(en)
|
2017-03-15 |
2018-09-20 |
F. Hoffmann-La Roche Ag |
Azaindoles as inhibitors of hpk1
|
|
CN110461346A
(zh)
|
2017-03-15 |
2019-11-15 |
美国安进公司 |
溶瘤病毒单独或与检查点抑制剂组合用于治疗癌症的用途
|
|
EP3596124A1
(en)
|
2017-03-16 |
2020-01-22 |
Innate Pharma |
Compositions and methods for treating cancer
|
|
KR20190129094A
(ko)
*
|
2017-03-17 |
2019-11-19 |
난토믹스, 엘엘씨 |
cfRNA에 대한 액체 생검(LIQUID BIOPSY FOR cfRNA)
|
|
EP3600427A1
(en)
|
2017-03-24 |
2020-02-05 |
INSERM - Institut National de la Santé et de la Recherche Médicale |
Methods and compositions for treating melanoma
|
|
CN108623686A
(zh)
|
2017-03-25 |
2018-10-09 |
信达生物制药(苏州)有限公司 |
抗ox40抗体及其用途
|
|
JOP20190224A1
(ar)
|
2017-03-29 |
2019-09-26 |
Iovance Biotherapeutics Inc |
عمليات من أجل إنتاج الخلايا اللمفاوية المرتشحة للأورام واستخداماتها في العلاج المناعي
|
|
US11254913B1
(en)
|
2017-03-29 |
2022-02-22 |
Iovance Biotherapeutics, Inc. |
Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy
|
|
US10407424B2
(en)
|
2017-03-30 |
2019-09-10 |
Genentech, Inc. |
Naphthyridines as inhibitors of HPK1
|
|
RU2765997C2
(ru)
|
2017-03-30 |
2022-02-07 |
Мерк Патент Гмбх |
Комбинация анти-pd-l1 антитела и ингибитора днк-пк для лечения злокачественного новообразования
|
|
BR112019019555A2
(pt)
|
2017-03-30 |
2020-04-22 |
Hoffmann La Roche |
composto de fórmula i, composição farmacêutica, método de inibição de hpk1, método para melhorar uma resposta imune, método para tratar um distúrbio e uso do composto
|
|
SG10202110594UA
(en)
|
2017-03-31 |
2021-11-29 |
Bristol Myers Squibb Co |
Methods of treating tumor
|
|
MX2019011858A
(es)
|
2017-04-03 |
2019-11-21 |
Oncologie Inc |
Metodos para tratar el cancer con anticuerpos dirigidos a ps con agentes inmunooncologicos.
|
|
MX2019011770A
(es)
|
2017-04-03 |
2020-01-09 |
Hoffmann La Roche |
Inmunoconjugados de un anticuerpo anti-pd-1 con un mutante il-2 o con il-15.
|
|
EP4516809A3
(en)
|
2017-04-05 |
2025-09-03 |
F. Hoffmann-La Roche AG |
Bispecific antibodies specifically binding to pd1 and lag3
|
|
IL269801B2
(en)
*
|
2017-04-05 |
2024-02-01 |
Korea Res Inst Bioscience & Biotechnology |
A fusion protein that activates NK cells, an NK cell, and a pharmaceutical preparation that includes them
|
|
US11603407B2
(en)
|
2017-04-06 |
2023-03-14 |
Regeneron Pharmaceuticals, Inc. |
Stable antibody formulation
|
|
TWI788340B
(zh)
|
2017-04-07 |
2023-01-01 |
美商必治妥美雅史谷比公司 |
抗icos促效劑抗體及其用途
|
|
WO2018191502A2
(en)
|
2017-04-13 |
2018-10-18 |
Agenus Inc. |
Anti-cd137 antibodies and methods of use thereof
|
|
JP2020516638A
(ja)
|
2017-04-13 |
2020-06-11 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
がんを処置する方法における使用のための、インターロイキン2イムノコンジュゲート、cd40アゴニスト、および任意選択のpd−1軸結合アンタゴニスト
|
|
MX2019012192A
(es)
|
2017-04-14 |
2020-01-21 |
Genentech Inc |
Métodos de diagnóstico y terapéuticos para el cáncer.
|
|
RU2665790C1
(ru)
|
2017-04-17 |
2018-09-04 |
Закрытое Акционерное Общество "Биокад" |
Моноклональное антитело к pd-l1
|
|
CN108728444A
(zh)
|
2017-04-18 |
2018-11-02 |
长春华普生物技术股份有限公司 |
免疫调节性多核苷酸及其应用
|
|
US12460208B2
(en)
|
2017-04-18 |
2025-11-04 |
Parr Biotechnology Co., Ltd. |
Immunomodulatory polynucleotides and uses thereof
|
|
AU2018255300B2
(en)
|
2017-04-18 |
2021-10-28 |
Tempest Therapeutics, Inc. |
Bicyclic compounds and their use in the treatment of cancer
|
|
JP2020517256A
(ja)
|
2017-04-19 |
2020-06-18 |
エルスター セラピューティクス, インコーポレイテッド |
多重特異性分子およびその使用
|
|
JOP20180040A1
(ar)
|
2017-04-20 |
2019-01-30 |
Gilead Sciences Inc |
مثبطات pd-1/pd-l1
|
|
CN106939049B
(zh)
|
2017-04-20 |
2019-10-01 |
苏州思坦维生物技术股份有限公司 |
拮抗抑制人pd-1抗原与其配体结合的单克隆抗体及其制备方法与应用
|
|
BR112019021680A2
(pt)
|
2017-04-20 |
2020-05-12 |
Adc Therapeutics Sa |
Terapia de combinação com conjugado anticorpo-fármaco anti-cd25??
|
|
ES2977788T3
(es)
|
2017-04-20 |
2024-08-30 |
Adc Therapeutics Sa |
Terapia combinada con un conjugado de anticuerpo anti-AXL y fármaco
|
|
CA3059939A1
(en)
|
2017-04-21 |
2018-10-25 |
Kyn Therapeutics |
Indole ahr inhibitors and uses thereof
|
|
EP3615070A1
(en)
|
2017-04-26 |
2020-03-04 |
Bristol-Myers Squibb Company |
Methods of antibody production that minimize disulfide bond reduction
|
|
AR111419A1
(es)
|
2017-04-27 |
2019-07-10 |
Novartis Ag |
Compuestos fusionados de indazol piridona como antivirales
|
|
CN108794467A
(zh)
|
2017-04-27 |
2018-11-13 |
博笛生物科技有限公司 |
2-氨基-喹啉衍生物
|
|
EP3615934A1
(en)
|
2017-04-28 |
2020-03-04 |
Merck Sharp & Dohme Corp. |
Biomarkers for cancer therapeutics
|
|
WO2018201051A1
(en)
|
2017-04-28 |
2018-11-01 |
Novartis Ag |
Bcma-targeting agent, and combination therapy with a gamma secretase inhibitor
|
|
AR111651A1
(es)
|
2017-04-28 |
2019-08-07 |
Novartis Ag |
Conjugados de anticuerpos que comprenden agonistas del receptor de tipo toll y terapias de combinación
|
|
UY37695A
(es)
|
2017-04-28 |
2018-11-30 |
Novartis Ag |
Compuesto dinucleótido cíclico bis 2’-5’-rr-(3’f-a)(3’f-a) y usos del mismo
|
|
WO2018201056A1
(en)
|
2017-04-28 |
2018-11-01 |
Novartis Ag |
Cells expressing a bcma-targeting chimeric antigen receptor, and combination therapy with a gamma secretase inhibitor
|
|
US20200385472A1
(en)
|
2017-04-28 |
2020-12-10 |
Elstar Therapeutics, Inc. |
Multispecific molecules comprising a non-immunoglobulin heterodimerization domain and uses thereof
|
|
WO2018204363A1
(en)
|
2017-05-01 |
2018-11-08 |
Agenus Inc. |
Anti-tigit antibodies and methods of use thereof
|
|
UY37718A
(es)
|
2017-05-05 |
2018-11-30 |
Novartis Ag |
2-quinolinonas triciclicas como agentes antibacteriales
|
|
TWI816673B
(zh)
|
2017-05-08 |
2023-10-01 |
大陸商上海津曼特生物科技有限公司 |
雙特異性重組蛋白及其應用
|
|
WO2018209049A1
(en)
|
2017-05-12 |
2018-11-15 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
|
IL300964A
(en)
|
2017-05-12 |
2023-04-01 |
Harpoon Therapeutics Inc |
mesothelin binding proteins
|
|
US11466047B2
(en)
|
2017-05-12 |
2022-10-11 |
Merck Sharp & Dohme Llc |
Cyclic di-nucleotide compounds as sting agonists
|
|
WO2018210230A1
(zh)
*
|
2017-05-16 |
2018-11-22 |
江苏恒瑞医药股份有限公司 |
一种pd-l1抗体药物组合物及其用途
|
|
US11359014B2
(en)
*
|
2017-05-16 |
2022-06-14 |
Alector Llc |
Anti-siglec-5 antibodies and methods of use thereof
|
|
KR20200006115A
(ko)
|
2017-05-16 |
2020-01-17 |
브리스톨-마이어스 스큅 컴퍼니 |
항-gitr 효능제 항체에 의한 암의 치료
|
|
WO2018213377A1
(en)
|
2017-05-17 |
2018-11-22 |
Arcus Biosciences, Inc. |
Quinazoline-pyrazole derivatives for the treatment of cancer-related disorders
|
|
WO2018213424A1
(en)
|
2017-05-17 |
2018-11-22 |
Boston Biomedical, Inc. |
Methods for treating cancer
|
|
JP7285220B2
(ja)
|
2017-05-18 |
2023-06-01 |
モデルナティエックス インコーポレイテッド |
連結したインターロイキン-12(il12)ポリペプチドをコードするポリヌクレオチドを含む脂質ナノ粒子
|
|
WO2018215936A1
(en)
|
2017-05-24 |
2018-11-29 |
Novartis Ag |
Antibody-cytokine engrafted proteins and methods of use in the treatment of cancer
|
|
SG10201913206RA
(en)
|
2017-05-25 |
2020-02-27 |
Bristol Myers Squibb Co |
Antibodies comprising modified heavy constant regions
|
|
AR111960A1
(es)
|
2017-05-26 |
2019-09-04 |
Incyte Corp |
Formas cristalinas de un inhibidor de fgfr y procesos para su preparación
|
|
CA3065304A1
(en)
|
2017-05-30 |
2018-12-06 |
Bristol-Myers Squibb Company |
Compositions comprising an anti-lag-3 antibody or an anti-lag-3 antibody and an anti-pd-1 or anti-pd-l1 antibody
|
|
AU2018277559A1
(en)
|
2017-05-30 |
2019-10-17 |
Bristol-Myers Squibb Company |
Compositions comprising a combination of an anti-LAG-3 antibody, a PD-1 pathway inhibitor, and an immunotherapeutic agent
|
|
HUE065242T2
(hu)
|
2017-05-30 |
2024-05-28 |
Bristol Myers Squibb Co |
LAG-3-pozitív tumorok kezelése
|
|
WO2018222685A1
(en)
|
2017-05-31 |
2018-12-06 |
Stcube & Co., Inc. |
Methods of treating cancer using antibodies and molecules that immunospecifically bind to btn1a1
|
|
JOP20190279A1
(ar)
|
2017-05-31 |
2019-11-28 |
Novartis Ag |
الصور البلورية من 5-برومو -2، 6-داي (1h-بيرازول -1-يل) بيريميدين -4- أمين وأملاح جديدة
|
|
US20210246227A1
(en)
|
2017-05-31 |
2021-08-12 |
Elstar Therapeutics, Inc. |
Multispecific molecules that bind to myeloproliferative leukemia (mpl) protein and uses thereof
|
|
EP3630838A1
(en)
|
2017-06-01 |
2020-04-08 |
CytomX Therapeutics, Inc. |
Activatable anti-pdl1 antibodies, and methods of use thereof
|
|
WO2018223004A1
(en)
|
2017-06-01 |
2018-12-06 |
Xencor, Inc. |
Bispecific antibodies that bind cd20 and cd3
|
|
CA3065929A1
(en)
|
2017-06-01 |
2018-12-06 |
Michael Wayne SAVILLE |
Bispecific antibodies that bind cd123 and cd3
|
|
JP7780857B2
(ja)
|
2017-06-01 |
2025-12-05 |
ブリストル-マイヤーズ スクイブ カンパニー |
抗pd-1抗体を用いる腫瘍の治療方法
|
|
US11413310B2
(en)
|
2017-06-02 |
2022-08-16 |
Juno Therapeutics, Inc. |
Articles of manufacture and methods for treatment using adoptive cell therapy
|
|
TW201919662A
(zh)
|
2017-06-05 |
2019-06-01 |
美商艾歐凡斯生物治療公司 |
對雙重難治性黑色素瘤使用腫瘤浸潤性淋巴細胞之方法
|
|
WO2018226671A1
(en)
|
2017-06-06 |
2018-12-13 |
Stcube & Co., Inc. |
Methods of treating cancer using antibodies and molecules that bind to btn1a1 or btn1a1-ligands
|
|
WO2018225093A1
(en)
|
2017-06-07 |
2018-12-13 |
Glaxosmithkline Intellectual Property Development Limited |
Chemical compounds as atf4 pathway inhibitors
|
|
WO2018224166A1
(en)
|
2017-06-09 |
2018-12-13 |
Biontech Rna Pharmaceuticals Gmbh |
Methods for predicting the usefulness of disease specific amino acid modifications for immunotherapy
|
|
CA3066048A1
(en)
|
2017-06-09 |
2018-12-13 |
Glaxosmithkline Intellectual Property Development Limited |
Combination therapy
|
|
US11572541B2
(en)
|
2017-06-09 |
2023-02-07 |
Providence Health & Services—Oregon |
Utilization of CD39 and CD103 for identification of human tumor reactive T cells for treatment of cancer
|
|
US11318211B2
(en)
|
2017-06-14 |
2022-05-03 |
Adc Therapeutics Sa |
Dosage regimes for the administration of an anti-CD19 ADC
|
|
WO2018229715A1
(en)
|
2017-06-16 |
2018-12-20 |
Novartis Ag |
Compositions comprising anti-cd32b antibodies and methods of use thereof
|
|
WO2018234862A1
(en)
|
2017-06-19 |
2018-12-27 |
Medicenna Therapeutics Inc. |
Uses and methods for il-2 superagonists, agonists, and fusions thereof
|
|
GB201709808D0
(en)
|
2017-06-20 |
2017-08-02 |
Kymab Ltd |
Antibodies
|
|
JP2020524157A
(ja)
|
2017-06-20 |
2020-08-13 |
アンスティテュート キュリー |
がん併用療法における使用のためのsuv39h1ヒストンメチルトランスフェラーゼの阻害剤
|
|
TW201904993A
(zh)
|
2017-06-22 |
2019-02-01 |
瑞士商諾華公司 |
IL-1β 結合抗體之用途
|
|
CA3066774A1
(en)
|
2017-06-22 |
2018-12-27 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
|
BR112019027402A2
(pt)
|
2017-06-22 |
2020-07-07 |
Celgene Corporation |
tratamento de carcinoma hepatocelular caracterizado por infecção pelo vírus da hepatite b
|
|
EP3642240A1
(en)
|
2017-06-22 |
2020-04-29 |
Novartis AG |
Antibody molecules to cd73 and uses thereof
|
|
WO2018235056A1
(en)
|
2017-06-22 |
2018-12-27 |
Novartis Ag |
Il-1beta binding antibodies for use in treating cancer
|
|
EP3641771A4
(en)
|
2017-06-23 |
2020-12-16 |
Birdie Biopharmaceuticals, Inc. |
PHARMACEUTICAL COMPOSITIONS
|
|
EP3642220A1
(en)
|
2017-06-23 |
2020-04-29 |
Bristol-Myers Squibb Company |
Immunomodulators acting as antagonists of pd-1
|
|
US11597768B2
(en)
|
2017-06-26 |
2023-03-07 |
Beigene, Ltd. |
Immunotherapy for hepatocellular carcinoma
|
|
CN111050791A
(zh)
|
2017-06-27 |
2020-04-21 |
诺华股份有限公司 |
用于抗tim-3抗体的给药方案及其用途
|
|
KR20220031738A
(ko)
|
2017-06-27 |
2022-03-11 |
주식회사 뉴라클사이언스 |
암 치료를 위한 항-fam19a5 항체의 용도
|
|
JP2020526194A
(ja)
|
2017-06-29 |
2020-08-31 |
ジュノー セラピューティクス インコーポレイテッド |
免疫療法薬と関連する毒性を評価するためのマウスモデル
|
|
US20190030018A1
(en)
|
2017-06-30 |
2019-01-31 |
Celgene Corporation |
Compositions and methods of use of 2-(4-chlorophenyl)-n-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)methyl)-2,2-difluoroacetamide
|
|
MX391848B
(es)
|
2017-06-30 |
2025-03-19 |
Bristol Myers Squibb Co |
Formas amorfas y cristalinas de inhibidores de indolamina 2,3-dioxigenasa (ido)
|
|
JP2020525513A
(ja)
|
2017-07-03 |
2020-08-27 |
グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited |
癌および他の疾患を治療するためのatf4阻害剤としてのn−(3−(2−(4−クロロフェノキシ)アセトアミドビシクロ[1.1.1]ペンタン−1−イル)−2−シクロブタン−1−カルボキサミド誘導体および関連化合物
|
|
JP2020525512A
(ja)
|
2017-07-03 |
2020-08-27 |
グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited |
癌および他の疾患を処置するためのATF4阻害剤としての2−(4−クロロフェノキシ)−N−((1−(2−(4−クロロフェノキシ)エチンアゼチジン(ethynazetidin)−3−イル)メチル)アセトアミド誘導体および関連化合物
|
|
GB201710973D0
(en)
|
2017-07-07 |
2017-08-23 |
Avacta Life Sciences Ltd |
Scaffold proteins
|
|
KR102656934B1
(ko)
|
2017-07-10 |
2024-04-16 |
셀진 코포레이션 |
항증식성 화합물 및 이의 사용 방법
|
|
BR112019027365A2
(pt)
|
2017-07-10 |
2020-07-14 |
Innate Pharma |
anticorpos, agentes, composição farmacêutica, kit, ácido nucleico, célula hospedeira, métodos de tratamento ou prevenção de doenças, de modulação de células, identificação de linfócitos e de seleção de pacientes e métodos in vitro de modulação e de determinação
|
|
CN107266572A
(zh)
*
|
2017-07-13 |
2017-10-20 |
无锡傲锐东源生物科技有限公司 |
抗pd‑l1蛋白单克隆抗体及其用途
|
|
CN110914258A
(zh)
|
2017-07-14 |
2020-03-24 |
先天肿瘤免疫公司 |
Nlrp3调节剂
|
|
WO2019016174A1
(en)
|
2017-07-18 |
2019-01-24 |
Institut Gustave Roussy |
METHOD FOR ASSESSING RESPONSE TO TARGETING DRUG PD-1 / PDL-1 MEDICINES
|
|
US20200172617A1
(en)
|
2017-07-20 |
2020-06-04 |
Novartis Ag |
Dosage regimens of anti-lag-3 antibodies and uses thereof
|
|
KR20240006698A
(ko)
|
2017-07-21 |
2024-01-15 |
제넨테크, 인크. |
암에 대한 치료 및 진단 방법
|
|
US11926664B2
(en)
|
2017-07-25 |
2024-03-12 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for modulating monocytopoiesis
|
|
WO2019021208A1
(en)
|
2017-07-27 |
2019-01-31 |
Glaxosmithkline Intellectual Property Development Limited |
USEFUL INDAZOLE DERIVATIVES AS PERK INHIBITORS
|
|
WO2019023624A1
(en)
|
2017-07-28 |
2019-01-31 |
Bristol-Myers Squibb Company |
PREDICTIVE PERIPHERAL BLOOD BIOMARKER FOR INHIBITORS OF CONTROL POINTS
|
|
EP3661522A2
(en)
|
2017-08-03 |
2020-06-10 |
Otsuka Pharmaceutical Co., Ltd. |
Drug compound and purification methods thereof
|
|
CA3071538A1
(en)
|
2017-08-04 |
2019-02-07 |
Merck Sharp & Dohme Corp. |
Benzo[b]thiophene sting agonists for cancer treatment
|
|
MA49773A
(fr)
|
2017-08-04 |
2021-04-21 |
Merck Sharp & Dohme |
Combinaisons d'antagonistes de pd-1 et d'agonistes de sting benzo[b
|
|
KR20250020679A
(ko)
|
2017-08-04 |
2025-02-11 |
젠맵 에이/에스 |
Pd-l1 및 cd137에 결합하는 결합제 및 그의 용도
|
|
JP7670481B2
(ja)
|
2017-08-04 |
2025-04-30 |
バイスクルテクス・リミテッド |
Cd137に対して特異的な二環式ペプチドリガンド
|
|
AU2018314227A1
(en)
|
2017-08-07 |
2020-02-06 |
Amgen Inc. |
Treatment of triple negative breast cancer or colorectal cancer with liver metastases with an anti PD-L1 antibody and an oncolytic virus
|
|
US10508115B2
(en)
|
2017-08-16 |
2019-12-17 |
Bristol-Myers Squibb Company |
Toll-like receptor 7 (TLR7) agonists having heteroatom-linked aromatic moieties, conjugates thereof, and methods and uses therefor
|
|
US10472361B2
(en)
|
2017-08-16 |
2019-11-12 |
Bristol-Myers Squibb Company |
Toll-like receptor 7 (TLR7) agonists having a benzotriazole moiety, conjugates thereof, and methods and uses therefor
|
|
US10494370B2
(en)
|
2017-08-16 |
2019-12-03 |
Bristol-Myers Squibb Company |
Toll-like receptor 7 (TLR7) agonists having a pyridine or pyrazine moiety, conjugates thereof, and methods and uses therefor
|
|
WO2019035938A1
(en)
|
2017-08-16 |
2019-02-21 |
Elstar Therapeutics, Inc. |
MULTISPECIFIC MOLECULES BINDING TO BCMA AND USES THEREOF
|
|
US10457681B2
(en)
|
2017-08-16 |
2019-10-29 |
Bristol_Myers Squibb Company |
Toll-like receptor 7 (TLR7) agonists having a tricyclic moiety, conjugates thereof, and methods and uses therefor
|
|
US10487084B2
(en)
|
2017-08-16 |
2019-11-26 |
Bristol-Myers Squibb Company |
Toll-like receptor 7 (TLR7) agonists having a heterobiaryl moiety, conjugates thereof, and methods and uses therefor
|
|
EP3668496A4
(en)
|
2017-08-17 |
2021-07-14 |
Ikena Oncology, Inc. |
AHR INHIBITORS AND THEIR USES
|
|
BR112020003533A2
(pt)
|
2017-08-25 |
2020-11-17 |
Five Prime Therapeutics, Inc. |
anticorpos b7-h4 e métodos de uso dos mesmos
|
|
SG11202001211TA
(en)
|
2017-08-28 |
2020-03-30 |
Bristol Myers Squibb Co |
Tim-3 antagonists for the treatment and diagnosis of cancers
|
|
WO2019046856A1
(en)
|
2017-09-04 |
2019-03-07 |
Agenus Inc. |
T-CELL RECEPTORS THAT BIND TO SPECIFIC PHOSPHOPEPTIDES OF MIXED LINEAR LEUKEMIA (MLL) AND METHODS OF USE THEREOF
|
|
TW201922721A
(zh)
|
2017-09-07 |
2019-06-16 |
英商葛蘭素史克智慧財產發展有限公司 |
化學化合物
|
|
WO2019051164A1
(en)
|
2017-09-07 |
2019-03-14 |
Augusta University Research Institute, Inc. |
ANTIBODIES AGAINST PROTEIN 1 OF PROGRAMMED CELL DEATH
|
|
WO2019053617A1
(en)
|
2017-09-12 |
2019-03-21 |
Glaxosmithkline Intellectual Property Development Limited |
CHEMICAL COMPOUNDS
|
|
JP7196160B2
(ja)
|
2017-09-12 |
2022-12-26 |
スミトモ ファーマ オンコロジー, インコーポレイテッド |
Mcl-1阻害剤アルボシジブを用いた、bcl-2阻害剤に対して非感受性である癌の治療レジメン
|
|
EP3684410A1
(en)
|
2017-09-19 |
2020-07-29 |
Institut Curie |
Agonist of aryl hydrocarbon receptor for use in cancer combination therapy
|
|
JP7382922B2
(ja)
|
2017-09-20 |
2023-11-17 |
中外製薬株式会社 |
Pd-1系結合アンタゴニストおよびgpc3標的化剤を使用する併用療法のための投与レジメン
|
|
WO2019060693A1
(en)
|
2017-09-22 |
2019-03-28 |
Kymera Therapeutics, Inc. |
CRBN LIGANDS AND USES THEREOF
|
|
AU2018338314B2
(en)
|
2017-09-22 |
2024-12-12 |
Kymera Therapeutics, Inc |
Protein degraders and uses thereof
|
|
EA039662B1
(ru)
|
2017-10-03 |
2022-02-24 |
Закрытое Акционерное Общество "Биокад" |
Антитела, специфичные к cd47 и pd-l1
|
|
US11492375B2
(en)
|
2017-10-03 |
2022-11-08 |
Bristol-Myers Squibb Company |
Cyclic peptide immunomodulators
|
|
WO2019069269A1
(en)
|
2017-10-05 |
2019-04-11 |
Glaxosmithkline Intellectual Property Development Limited |
INTERFERON GENE STIMULATOR MODULATORS USEFUL IN THE TREATMENT OF HIV
|
|
WO2019069270A1
(en)
|
2017-10-05 |
2019-04-11 |
Glaxosmithkline Intellectual Property Development Limited |
GENERATOR STIMULATOR MODULATORS (STING) INTERFERON
|
|
CN111542539B
(zh)
|
2017-10-06 |
2023-10-20 |
先天制药公司 |
通过cd39/cd73轴恢复t细胞活性
|
|
WO2019074822A1
(en)
|
2017-10-09 |
2019-04-18 |
Bristol-Myers Squibb Company |
INDOLEAMINE 2,3-DIOXYGENASE INHIBITORS AND METHODS OF USE
|
|
WO2019074824A1
(en)
|
2017-10-09 |
2019-04-18 |
Bristol-Myers Squibb Company |
INDOLEAMINE 2,3-DIOXYGENASE INHIBITORS AND METHODS OF USE
|
|
EP3694880A1
(en)
|
2017-10-10 |
2020-08-19 |
Numab Therapeutics AG |
Antibodies targeting cd137 and methods of use thereof
|
|
EP3470426A1
(en)
|
2017-10-10 |
2019-04-17 |
Numab Therapeutics AG |
Multispecific antibody
|
|
BR112020006999A2
(pt)
|
2017-10-10 |
2020-10-06 |
Numab Therapeutics AG |
anticorpo multiespecífico, composição farmacêutica e método de produção
|
|
US11525002B2
(en)
|
2017-10-11 |
2022-12-13 |
Board Of Regents, The University Of Texas System |
Human PD-L1 antibodies and methods of use therefor
|
|
US11713356B2
(en)
|
2017-10-13 |
2023-08-01 |
Ose Immunotherapeutics |
Modified bifunctional anti-human signal regulatory protein alpha (SIRPa) antibody and method of use thereof for treating cancer
|
|
IL315737A
(en)
|
2017-10-13 |
2024-11-01 |
Harpoon Therapeutics Inc |
B-cell maturation antigen-binding proteins
|
|
CN111630070B
(zh)
|
2017-10-13 |
2024-07-30 |
哈普恩治疗公司 |
三特异性蛋白质及使用方法
|
|
WO2019075468A1
(en)
|
2017-10-15 |
2019-04-18 |
Bristol-Myers Squibb Company |
TUMOR TREATMENT METHODS
|
|
US20200283500A1
(en)
|
2017-10-18 |
2020-09-10 |
Alpine Immune Sciences, Inc. |
Variant icos ligand immunomodulatory proteins and related compositions and methods
|
|
CA3079310A1
(en)
|
2017-10-18 |
2019-04-25 |
Vivia Biotech, S.L. |
Bite-activated car-t cells
|
|
CA3078155A1
(en)
|
2017-10-19 |
2019-04-25 |
Debiopharm International S.A. |
Combination product for the treatment of cancer
|
|
WO2019081983A1
(en)
|
2017-10-25 |
2019-05-02 |
Novartis Ag |
CD32B TARGETING ANTIBODIES AND METHODS OF USE
|
|
WO2019089753A2
(en)
|
2017-10-31 |
2019-05-09 |
Compass Therapeutics Llc |
Cd137 antibodies and pd-1 antagonists and uses thereof
|
|
KR20200074997A
(ko)
|
2017-11-01 |
2020-06-25 |
주노 쎄러퓨티크스 인코퍼레이티드 |
B-세포 성숙 항원에 특이적인 항체 및 키메릭 항원 수용체
|
|
EP3703692B1
(en)
|
2017-11-01 |
2025-07-23 |
Merck Sharp & Dohme LLC |
Novel substituted tetrahydroquinolin compounds as indoleamine 2,3-dioxygenase (ido) inhibitors
|
|
TW201932482A
(zh)
|
2017-11-01 |
2019-08-16 |
美商奇諾治療有限公司 |
對b細胞成熟抗原具特異性之嵌合抗原受體及編碼聚核苷酸
|
|
KR20200074214A
(ko)
|
2017-11-01 |
2020-06-24 |
브리스톨-마이어스 스큅 컴퍼니 |
암을 치료하는데 사용하기 위한 면역자극 효능작용 항체
|
|
WO2019089858A2
(en)
|
2017-11-01 |
2019-05-09 |
Juno Therapeutics, Inc. |
Methods of assessing or monitoring a response to a cell therapy
|
|
EP3707138B1
(en)
|
2017-11-06 |
2022-07-13 |
Bristol-Myers Squibb Company |
Isofuranone compounds useful as hpk1 inhibitors
|
|
AU2018360790A1
(en)
|
2017-11-06 |
2020-06-11 |
Bristol-Myers Squibb Company |
Methods of treating a tumor
|
|
PL3707510T3
(pl)
|
2017-11-06 |
2024-09-30 |
F. Hoffmann-La Roche Ag |
Sposoby diagnostyczne i terapeutyczne w chorobach nowotworowych
|
|
CN111886012A
(zh)
|
2017-11-06 |
2020-11-03 |
朱诺治疗学股份有限公司 |
细胞疗法与γ分泌酶抑制剂的组合
|
|
CN111315398A
(zh)
|
2017-11-10 |
2020-06-19 |
阿尔莫生物科技股份有限公司 |
白介素-10与免疫检查点途径抑制剂的组合的组合物和使用方法
|
|
US10647705B2
(en)
|
2017-11-14 |
2020-05-12 |
Merck Sharp & Dohme Corp. |
Substituted biaryl compounds as indoleamine 2,3-dioxygenase (IDO) inhibitors
|
|
KR20200088386A
(ko)
|
2017-11-14 |
2020-07-22 |
화이자 인코포레이티드 |
Ezh2 억제제 병용 요법
|
|
WO2019099294A1
(en)
|
2017-11-14 |
2019-05-23 |
Merck Sharp & Dohme Corp. |
Novel substituted biaryl compounds as indoleamine 2,3-dioxygenase (ido) inhibitors
|
|
EP3710455A1
(en)
|
2017-11-17 |
2020-09-23 |
Novartis AG |
Novel dihydroisoxazole compounds and their use for the treatment of hepatitis b
|
|
AU2018368786B2
(en)
|
2017-11-17 |
2025-05-22 |
Iovance Biotherapeutics, Inc. |
TIL expansion from fine needle aspirates and small biopsies
|
|
JOP20200131A1
(ar)
|
2017-11-17 |
2020-05-28 |
Merck Sharp & Dohme |
أجسام مضادة خاصة بنسخة تشبه جلوبيولين مناعي 3 (ilt3) واستخدامتها
|
|
EP3713596A1
(en)
|
2017-11-24 |
2020-09-30 |
Institut National de la Santé Et de la Recherche Médicale |
Methods and compositions for treating cancers
|
|
EP3717021A1
(en)
|
2017-11-27 |
2020-10-07 |
Mersana Therapeutics, Inc. |
Pyrrolobenzodiazepine antibody conjugates
|
|
US11786529B2
(en)
|
2017-11-29 |
2023-10-17 |
Beigene Switzerland Gmbh |
Treatment of indolent or aggressive B-cell lymphomas using a combination comprising BTK inhibitors
|
|
RU2020121458A
(ru)
|
2017-11-30 |
2021-12-30 |
Новартис Аг |
Химерный антигенный рецептор, нацеливающийся на bcma, и его пути применения
|
|
CN111356702B
(zh)
*
|
2017-12-06 |
2022-07-26 |
正大天晴药业集团南京顺欣制药有限公司 |
抗pd-l1抗体及其抗原结合片段
|
|
JP7348899B2
(ja)
|
2017-12-08 |
2023-09-21 |
マレンゴ・セラピューティクス,インコーポレーテッド |
多重特異性分子及びその使用
|
|
US11946094B2
(en)
|
2017-12-10 |
2024-04-02 |
Augusta University Research Institute, Inc. |
Combination therapies and methods of use thereof
|
|
EP3724205B1
(en)
|
2017-12-15 |
2022-06-22 |
Janssen Biotech, Inc. |
Cyclic dinucleotides as sting agonists
|
|
CN112204048A
(zh)
|
2017-12-15 |
2021-01-08 |
朱诺治疗学股份有限公司 |
抗cct5结合分子及其使用方法
|
|
EP3728316B1
(en)
|
2017-12-19 |
2025-02-26 |
invoX Pharma Limited |
Fc binding fragments comprising a pd-l1 antigen-binding site
|
|
GB201721338D0
(en)
|
2017-12-19 |
2018-01-31 |
Kymab Ltd |
Anti-icos Antibodies
|
|
EP3728314A1
(en)
|
2017-12-19 |
2020-10-28 |
Kymab Limited |
Bispecific antibody for icos and pd-l1
|
|
AU2018388791B2
(en)
|
2017-12-19 |
2025-04-03 |
The Rockefeller University |
Human IgG Fc domain variants with improved effector function
|
|
EP3728266A1
(en)
|
2017-12-20 |
2020-10-28 |
Novartis AG |
Fused tricyclic pyrazolo-dihydropyrazinyl-pyridone compounds as antivirals
|
|
WO2019125974A1
(en)
|
2017-12-20 |
2019-06-27 |
Merck Sharp & Dohme Corp. |
Cyclic di-nucleotide compounds as sting agonists
|
|
CN111757757A
(zh)
|
2017-12-21 |
2020-10-09 |
梅尔莎纳医疗公司 |
吡咯并苯并二氮呯抗体共轭物
|
|
IL315310A
(en)
|
2017-12-26 |
2024-10-01 |
Kymera Therapeutics Inc |
Irak degraders and uses thereof
|
|
CN109970856B
(zh)
|
2017-12-27 |
2022-08-23 |
信达生物制药(苏州)有限公司 |
抗lag-3抗体及其用途
|
|
WO2019129137A1
(zh)
|
2017-12-27 |
2019-07-04 |
信达生物制药(苏州)有限公司 |
抗lag-3抗体及其用途
|
|
WO2019129054A1
(zh)
|
2017-12-27 |
2019-07-04 |
信达生物制药(苏州)有限公司 |
三链抗体、其制备方法及其用途
|
|
CN115925943A
(zh)
*
|
2017-12-27 |
2023-04-07 |
信达生物制药(苏州)有限公司 |
抗pd-l1抗体及其用途
|
|
CN111788227B
(zh)
|
2017-12-27 |
2025-02-25 |
百时美施贵宝公司 |
抗cd40抗体及其用途
|
|
CN111770759A
(zh)
|
2017-12-28 |
2020-10-13 |
通用医疗公司 |
靶向cbm信号体复合物诱导调节性t细胞使肿瘤微环境发炎
|
|
SG11202003893UA
(en)
|
2017-12-29 |
2020-05-28 |
Ap Biosciences Inc |
Monospecific and bispecific proteins with immune checkpoint regulation for cancer therapy
|
|
EP3731850A4
(en)
|
2017-12-29 |
2021-12-01 |
Oncorus, Inc. |
ONCOLYTIC VIRUS DELIVERY OF THERAPEUTIC POLYPEPTIDES
|
|
WO2019134946A1
(en)
|
2018-01-04 |
2019-07-11 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma resistant
|
|
US11324774B2
(en)
|
2018-01-05 |
2022-05-10 |
Augusta University Research Institute, Inc. |
Compositions of oral alkaline salts and metabolic acid inducers and uses thereof
|
|
US11447449B2
(en)
|
2018-01-05 |
2022-09-20 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
|
TW201930591A
(zh)
|
2018-01-08 |
2019-08-01 |
瑞士商諾華公司 |
用於與嵌合抗原受體療法併用之免疫增強rna
|
|
MX2020007046A
(es)
|
2018-01-08 |
2020-09-07 |
Iovance Biotherapeutics Inc |
Procesos para generar productos de linfocitos infiltrantes de tumores (til) enriquecidos para celulas t especificas de antigenos tumorales.
|
|
US11713446B2
(en)
|
2018-01-08 |
2023-08-01 |
Iovance Biotherapeutics, Inc. |
Processes for generating TIL products enriched for tumor antigen-specific T-cells
|
|
WO2019136459A1
(en)
|
2018-01-08 |
2019-07-11 |
Iovance Biotherapeutics, Inc. |
Processes for generating til products enriched for tumor antigen-specific t-cells
|
|
WO2019139987A1
(en)
|
2018-01-09 |
2019-07-18 |
Elstar Therapeutics, Inc. |
Calreticulin binding constructs and engineered t cells for the treatment of diseases
|
|
ES2983284T3
(es)
|
2018-01-09 |
2024-10-22 |
Shuttle Pharmaceuticals Inc |
Inhibidores selectivos de histona deacetilasa para el tratamiento de enfermedades humanas
|
|
MX2020007406A
(es)
*
|
2018-01-10 |
2020-09-14 |
Jiangsu Hengrui Medicine Co |
Anticuerpo pd-l1, fragmento de union al antigeno del mismo y uso farmaceutico del mismo.
|
|
EP3737700A1
(en)
|
2018-01-12 |
2020-11-18 |
Bristol-Myers Squibb Company |
Antibodies against tim3 and uses thereof
|
|
EP3737675A4
(en)
|
2018-01-12 |
2022-01-05 |
Kymera Therapeutics, Inc. |
Crbn ligands and uses thereof
|
|
CN112135610A
(zh)
|
2018-01-12 |
2020-12-25 |
KDAc治疗股份有限公司 |
用于治疗癌症的选择性组蛋白去乙酰酶3(hdac3)抑制剂及免疫治疗剂的组合
|
|
EP3737666A4
(en)
|
2018-01-12 |
2022-01-05 |
Kymera Therapeutics, Inc. |
PROTEIN DEGRADATION AGENTS AND ASSOCIATED USES
|
|
CN111770936A
(zh)
|
2018-01-12 |
2020-10-13 |
百时美施贵宝公司 |
抗il-8抗体和抗pd-1抗体联合治疗用于治疗癌症
|
|
CN111868091A
(zh)
|
2018-01-16 |
2020-10-30 |
百时美施贵宝公司 |
用抗tim3抗体治疗癌症的方法
|
|
WO2019143884A1
(en)
*
|
2018-01-19 |
2019-07-25 |
Vanderbilt University |
Conserved hiv antibody clonotypes and methods of use
|
|
US12398209B2
(en)
|
2018-01-22 |
2025-08-26 |
Janssen Biotech, Inc. |
Methods of treating cancers with antagonistic anti-PD-1 antibodies
|
|
MX2020007526A
(es)
|
2018-01-22 |
2020-09-09 |
Bristol Myers Squibb Co |
Composiciones y metodos para tratar el cancer.
|
|
EP3743061A1
(en)
|
2018-01-22 |
2020-12-02 |
Pascal Biosciences Inc. |
Cannabinoids and derivatives for promoting immunogenicity of tumor and infected cells
|
|
JP2021512151A
(ja)
|
2018-01-23 |
2021-05-13 |
ネクストキュア インコーポレイテッド |
B7−h4抗体およびその使用方法
|
|
WO2019147615A1
(en)
|
2018-01-24 |
2019-08-01 |
Beyondspring Pharmaceuticals, Inc. |
Composition and method for reducing thrombocytopenia via the administration of plinabulin
|
|
WO2019148089A1
(en)
|
2018-01-26 |
2019-08-01 |
Orionis Biosciences Inc. |
Xcr1 binding agents and uses thereof
|
|
EP4616913A3
(en)
|
2018-01-29 |
2025-12-10 |
Merck Patent GmbH |
Gcn2 inhibitors and uses thereof
|
|
CN111867581B
(zh)
|
2018-01-29 |
2023-12-26 |
默克专利股份有限公司 |
Gcn2抑制剂及其用途
|
|
JP2021511793A
(ja)
|
2018-01-31 |
2021-05-13 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
Lag3に結合する抗原結合部位を含む二重特異性抗体
|
|
US20210038659A1
(en)
|
2018-01-31 |
2021-02-11 |
Novartis Ag |
Combination therapy using a chimeric antigen receptor
|
|
US20210069246A1
(en)
|
2018-01-31 |
2021-03-11 |
Celgene Corporation |
Combination therapy using adoptive cell therapy and checkpoint inhibitor
|
|
JP2021513512A
(ja)
|
2018-02-05 |
2021-05-27 |
シェンチェン イオノヴァ ライフ サイエンス カンパニー リミテッドShenzhen Ionova Life Science Co., Ltd. |
癌または炎症性疾患の治療のためのヘテロ二環式カルボキシ酸
|
|
JP2021513361A
(ja)
|
2018-02-05 |
2021-05-27 |
オリオニス バイオサイエンシーズ,インコーポレイテッド |
線維芽細胞結合物質およびその使用
|
|
US20200405806A1
(en)
|
2018-02-08 |
2020-12-31 |
Bristol-Myers Squibb Company |
Combination of a tetanus toxoid, anti-ox40 antibody and/or anti-pd-1 antibody to treat tumors
|
|
NL2020422B1
(en)
|
2018-02-12 |
2019-08-19 |
Stichting Het Nederlands Kanker Inst Antoni Van Leeuwenhoek Ziekenhuis |
Methods for Predicting Treatment Outcome and/or for Selecting a Subject Suitable for Immune Checkpoint Therapy.
|
|
EP3752203A1
(en)
|
2018-02-13 |
2020-12-23 |
Novartis AG |
Chimeric antigen receptor therapy in combination with il-15r and il15
|
|
WO2019160866A2
(en)
|
2018-02-13 |
2019-08-22 |
Checkmate Pharmaceuticals, Inc. |
Compositions and methods for tumor immunotherapy
|
|
UA126458C2
(uk)
|
2018-02-13 |
2022-10-05 |
Гіліад Сайєнсіз, Інк. |
Інгібітори pd-1/pd-l1
|
|
AU2019222747B2
(en)
|
2018-02-16 |
2024-09-05 |
Arcus Biosciences, Inc. |
Dosing with an azolopyrimidine compound
|
|
BR112020016986A2
(pt)
|
2018-02-21 |
2021-03-02 |
Five Prime Therapeutics, Inc. |
formulações de anticorpo contra b7-h4
|
|
EP3756012A1
(en)
|
2018-02-21 |
2020-12-30 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of sk1 as biomarker for predicting response to immunecheckpoint inhibitors
|
|
CA3091775A1
(en)
|
2018-02-23 |
2019-08-29 |
Bicycletx Limited |
Multimeric bicyclic peptide ligands
|
|
WO2019165315A1
(en)
|
2018-02-23 |
2019-08-29 |
Syntrix Biosystems Inc. |
Method for treating cancer using chemokine antagonists alone or in combination
|
|
MX2020008882A
(es)
|
2018-02-26 |
2021-01-08 |
Genentech Inc |
Dosificación para tratamiento con anticuerpos antagonistas anti-tigit y anti-pd-l1.
|
|
PE20211001A1
(es)
|
2018-02-27 |
2021-06-01 |
Incyte Corp |
Imidazopirimidinas y triazolopirimidinas como inhibidores de a2a / a2b
|
|
WO2019166951A1
(en)
|
2018-02-28 |
2019-09-06 |
Novartis Ag |
Indole-2-carbonyl compounds and their use for the treatment of hepatitis b
|
|
WO2019169229A1
(en)
|
2018-03-01 |
2019-09-06 |
Nextcure, Inc. |
Klrg1 binding compositions and methods of use thereof
|
|
WO2019166650A1
(en)
|
2018-03-02 |
2019-09-06 |
Cdr-Life Ag |
Trispecific antigen binding proteins
|
|
EP3759142A1
(en)
|
2018-03-02 |
2021-01-06 |
Five Prime Therapeutics, Inc. |
B7-h4 antibodies and methods of use thereof
|
|
CR20200445A
(es)
|
2018-03-05 |
2021-04-27 |
Arcus Biosciences Inc |
Inhibidores de la arginasa
|
|
EP3762105A1
(en)
|
2018-03-06 |
2021-01-13 |
Institut Curie |
Inhibitor of setdb1 histone methyltransferase for use in cancer combination therapy
|
|
US20210030703A1
(en)
|
2018-03-12 |
2021-02-04 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of caloric restriction mimetics for potentiating chemo-immunotherapy for the treatment of cancers
|
|
US12215116B2
(en)
|
2018-03-13 |
2025-02-04 |
Merck Sharp & Dohme Llc |
Arginase inhibitors and methods of use
|
|
JP2021517130A
(ja)
|
2018-03-13 |
2021-07-15 |
オーセ イミュノセラピューティクスOse Immunotherapeutics |
抗ヒトSIRPav1抗体の使用および抗v1抗体を製造する方法
|
|
SG11202008390SA
(en)
|
2018-03-14 |
2020-09-29 |
Surface Oncology Inc |
Antibodies that bind cd39 and uses thereof
|
|
WO2019178364A2
(en)
|
2018-03-14 |
2019-09-19 |
Elstar Therapeutics, Inc. |
Multifunctional molecules and uses thereof
|
|
US12152073B2
(en)
|
2018-03-14 |
2024-11-26 |
Marengo Therapeutics, Inc. |
Multifunctional molecules that bind to calreticulin and uses thereof
|
|
AU2019233596A1
(en)
|
2018-03-14 |
2020-10-08 |
Merck Patent Gmbh |
Compounds and uses thereof to treat tumors in a subject
|
|
JP2021518380A
(ja)
*
|
2018-03-19 |
2021-08-02 |
アベオメ コーポレーション |
プログラム細胞死リガンド1(pd−l1)に対する高親和性中和モノクローナル抗体、及びその使用
|
|
US11458171B2
(en)
*
|
2018-03-21 |
2022-10-04 |
China Medical University |
Engineering stem cells for cancer therapy
|
|
TW201945393A
(zh)
|
2018-03-21 |
2019-12-01 |
美商戊瑞治療有限公司 |
在酸性pH結合至VISTA之抗體
|
|
MA52094A
(fr)
|
2018-03-22 |
2021-01-27 |
Adimab Llc |
Anticorps anti-il-27 et leurs utilisations
|
|
AU2019239568B2
(en)
|
2018-03-23 |
2025-09-11 |
Board Of Regents, The University Of Texas System |
Dual specificity antibodies to human PD-L1 and PD-L2 and methods of use therefor
|
|
EP4501355A3
(en)
|
2018-03-23 |
2025-04-30 |
Board Of Regents, The University Of Texas System |
Dual specificity antibodies to pd-l1 and pd-l2 and methods of use therefor
|
|
US11976128B2
(en)
|
2018-03-23 |
2024-05-07 |
Board Of Regents, The University Of Texas System |
Human PD-L2 antibodies and methods of use therefor
|
|
US11242393B2
(en)
|
2018-03-23 |
2022-02-08 |
Bristol-Myers Squibb Company |
Antibodies against MICA and/or MICB and uses thereof
|
|
WO2019184909A1
(zh)
|
2018-03-27 |
2019-10-03 |
信达生物制药(苏州)有限公司 |
新型抗体分子、其制备方法及其用途
|
|
JP2021519284A
(ja)
*
|
2018-03-27 |
2021-08-10 |
ラボラトリー コーポレイション オブ アメリカ ホールディングス |
治療薬による処置から利益を受けうる被験体を特定するためのサンドウィッチelisa
|
|
CN110305210B
(zh)
|
2018-03-27 |
2023-02-28 |
信达生物制药(苏州)有限公司 |
新型抗体分子、其制备方法及其用途
|
|
WO2019185792A1
(en)
|
2018-03-29 |
2019-10-03 |
Philogen S.P.A |
Cancer treatment using immunoconjugates and immune check-point inhibitors
|
|
WO2019185035A1
(en)
*
|
2018-03-29 |
2019-10-03 |
Adagene Inc. |
Anti-pd-l1 antibodies and use thereof
|
|
PT3775165T
(pt)
|
2018-03-29 |
2024-07-17 |
Iovance Biotherapeutics Inc |
Processos para produção de linfócitos infiltrantes de tumor e utilizações dos mesmos em imunoterapia
|
|
CN111971306A
(zh)
|
2018-03-30 |
2020-11-20 |
百时美施贵宝公司 |
治疗肿瘤的方法
|
|
FI4212529T3
(fi)
|
2018-03-30 |
2025-04-23 |
Incyte Corp |
Heterosyklisiä yhdisteitä immunomodulaattoreina
|
|
EP3774764A1
(en)
|
2018-04-03 |
2021-02-17 |
Merck Sharp&Dohme Corp. |
Benzothiophenes and related compounds as sting agonists
|
|
US11702430B2
(en)
|
2018-04-03 |
2023-07-18 |
Merck Sharp & Dohme Llc |
Aza-benzothiophene compounds as STING agonists
|
|
EP3774903A1
(en)
|
2018-04-04 |
2021-02-17 |
Bristol-Myers Squibb Company |
Anti-cd27 antibodies and uses thereof
|
|
US11874276B2
(en)
|
2018-04-05 |
2024-01-16 |
Dana-Farber Cancer Institute, Inc. |
STING levels as a biomarker for cancer immunotherapy
|
|
WO2019193541A1
(en)
|
2018-04-06 |
2019-10-10 |
Glaxosmithkline Intellectual Property Development Limited |
Bicyclic aromatic ring derivatives of formula (i) as atf4 inhibitors
|
|
WO2019193540A1
(en)
|
2018-04-06 |
2019-10-10 |
Glaxosmithkline Intellectual Property Development Limited |
Heteroaryl derivatives of formula (i) as atf4 inhibitors
|
|
IL297847B2
(en)
*
|
2018-04-09 |
2024-02-01 |
Origincell Therapeutics Co Ltd |
Anti-PD-L1 antibody and its use
|
|
JP7511478B2
(ja)
|
2018-04-09 |
2024-07-05 |
チェックメイト ファーマシューティカルズ |
ウイルス様粒子中へのオリゴヌクレオチドのパッケージ化
|
|
BR112020020826A2
(pt)
|
2018-04-12 |
2021-01-19 |
Bristol-Myers Squibb Company |
Terapia de combinação anticâncer com anticorpo antagonista de cd73 e anticorpo antagonista do eixo pd-1/pd-l1
|
|
US20210147547A1
(en)
|
2018-04-13 |
2021-05-20 |
Novartis Ag |
Dosage Regimens For Anti-Pd-L1 Antibodies And Uses Thereof
|
|
JP7054573B2
(ja)
*
|
2018-04-15 |
2022-04-14 |
イムヴィラ・カンパニー・リミテッド |
Pd-1結合抗体及びその用途
|
|
CA3096546A1
(en)
|
2018-04-16 |
2019-10-24 |
Arrys Therapeutics, Inc. |
Ep4 inhibitors and use thereof
|
|
CN113975264A
(zh)
|
2018-04-16 |
2022-01-28 |
上海岸阔医药科技有限公司 |
预防或治疗肿瘤疗法副作用的方法
|
|
CA3096894A1
(en)
|
2018-04-17 |
2019-10-24 |
Tempest Therapeutics, Inc. |
Bicyclic carboxamides and methods of use thereof
|
|
MX2019009726A
(es)
|
2018-04-17 |
2020-02-05 |
Molecular Templates Inc |
Moleculas con direccion hacia her2 que comprenden andamiajes de la sub-unidad a de la toxina shiga desinmunizados.
|
|
JP7466459B2
(ja)
|
2018-04-17 |
2024-04-12 |
セルデックス セラピューティクス インコーポレイテッド |
抗cd27および抗pd-l1抗体ならびに二重特異性構築物
|
|
JP2021521784A
(ja)
|
2018-04-18 |
2021-08-30 |
ゼンコア インコーポレイテッド |
IL−15/IL−15RaFc融合タンパク質とPD−1抗原結合ドメインを含むPD−1標的化ヘテロダイマー融合タンパク質およびそれらの使用
|
|
TWI851572B
(zh)
|
2018-04-18 |
2024-08-11 |
美商山可爾股份有限公司 |
IL-15/IL-15Rα異二聚體Fc融合蛋白及其用途
|
|
CA3093715A1
(en)
|
2018-04-19 |
2019-10-24 |
Checkmate Pharmaceuticals, Inc. |
Synthetic rig-i-like receptor agonists
|
|
US10899735B2
(en)
|
2018-04-19 |
2021-01-26 |
Gilead Sciences, Inc. |
PD-1/PD-L1 inhibitors
|
|
EP3781687A4
(en)
|
2018-04-20 |
2022-02-09 |
Merck Sharp & Dohme Corp. |
NEW RIG-I SUBSTITUTED AGONISTS: COMPOSITIONS AND METHODS THEREOF
|
|
US11485741B2
(en)
|
2018-04-24 |
2022-11-01 |
Bristol-Myers Squibb Company |
Macrocyclic toll-like receptor 7 (TLR7) agonists
|
|
MX2020011234A
(es)
|
2018-04-25 |
2020-11-11 |
Innate Tumor Immunity Inc |
Moduladores de receptor similar al dominio de oligomerizacion de union a nucleotidos que contiene dominio de pirina 3 (nlrp3).
|
|
WO2019207030A1
(en)
|
2018-04-26 |
2019-10-31 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting a response with an immune checkpoint inhibitor in a patient suffering from a lung cancer
|
|
WO2019210055A2
(en)
|
2018-04-26 |
2019-10-31 |
Agenus Inc. |
Heat shock protein-binding peptide compositions and methods of use thereof
|
|
MA52533A
(fr)
|
2018-04-27 |
2021-03-03 |
Iovance Biotherapeutics Inc |
Procédé en circuit fermé pour l'amplification et l'edition de gènes de lymphocytes d'infiltration des tumeurs et leurs utilisations en immunothérapie
|
|
WO2019210153A1
(en)
|
2018-04-27 |
2019-10-31 |
Novartis Ag |
Car t cell therapies with enhanced efficacy
|
|
US12048745B2
(en)
|
2018-05-01 |
2024-07-30 |
Augusta University Research Institute, Inc. |
Methods for detecting and reversing immune therapy resistance
|
|
EP3788369A1
(en)
|
2018-05-01 |
2021-03-10 |
Novartis Ag |
Biomarkers for evaluating car-t cells to predict clinical outcome
|
|
US12037323B2
(en)
|
2018-05-03 |
2024-07-16 |
Bristol-Myers Squibb Company |
Uracil derivatives as Mer-AXL inhibitors
|
|
EP3788079A4
(en)
|
2018-05-03 |
2022-12-21 |
Shanghai Epimab Biotherapeutics Co., Ltd. |
High affinity antibodies to pd-1 and lag-3 and bispecific binding proteins made therefrom
|
|
WO2019211489A1
(en)
|
2018-05-04 |
2019-11-07 |
Merck Patent Gmbh |
COMBINED INHIBITION OF PD-1/PD-L1, TGFβ AND DNA-PK FOR THE TREATMENT OF CANCER
|
|
BR112020022373A2
(pt)
|
2018-05-04 |
2021-02-02 |
Incyte Corporation |
sais de um inibidor de fgfr
|
|
CN112352052A
(zh)
|
2018-05-04 |
2021-02-09 |
托利斯有限公司 |
激活上皮细胞和髓样细胞的tlr3配体
|
|
EP3788047B1
(en)
|
2018-05-04 |
2024-09-04 |
Incyte Corporation |
Solid forms of an fgfr inhibitor and processes for preparing the same
|
|
US12473532B2
(en)
|
2018-05-10 |
2025-11-18 |
Iovance Biotherapeutics, Inc. |
Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy
|
|
SMT202300127T1
(it)
|
2018-05-11 |
2023-05-12 |
Incyte Corp |
Derivati di tetraidro-imidazo[4,5-c]piridina come immunomodulatori di pd-l1
|
|
PL3793565T3
(pl)
|
2018-05-14 |
2022-05-02 |
Gilead Sciences, Inc. |
Inhibitory MCL-1
|
|
KR102885515B1
(ko)
|
2018-05-15 |
2025-11-12 |
메디뮨 리미티드 |
암의 치료
|
|
GB201807924D0
(en)
|
2018-05-16 |
2018-06-27 |
Ctxt Pty Ltd |
Compounds
|
|
US11136394B2
(en)
*
|
2018-05-17 |
2021-10-05 |
Nanjing Leads Biolabs Co., Ltd. |
Antibody binding PD-1 and use thereof
|
|
MA52940A
(fr)
|
2018-05-18 |
2021-04-28 |
Incyte Corp |
Dérivés de pyrimidine fusionnés utilisés en tant qu'inhibiteurs de a2a/a2b
|
|
CN112492874A
(zh)
|
2018-05-23 |
2021-03-12 |
细胞基因公司 |
治疗多发性骨髓瘤以及生物标志物对于4-(4-(4-(((2-(2,6-二氧代哌啶-3-基)-1-氧代异吲哚啉-4-基)氧基)甲基)苄基)哌嗪-1-基)-3-氟苄腈的用途
|
|
SG11202010469QA
(en)
|
2018-05-23 |
2020-11-27 |
Adc Therapeutics Sa |
Molecular adjuvant
|
|
PL3796912T3
(pl)
|
2018-05-23 |
2023-09-11 |
Celgene Corporation |
Związki przeciwproliferacyjne i przeciwciało bispecyficzne przeciwko bcma i cd3 do zastosowania kombinowanego
|
|
CN112188902A
(zh)
|
2018-05-29 |
2021-01-05 |
百时美施贵宝公司 |
用于前药和缀合物的经修饰的自消灭部分以及使用和制造方法
|
|
UY38247A
(es)
|
2018-05-30 |
2019-12-31 |
Novartis Ag |
Anticuerpos frente a entpd2, terapias de combinación y métodos de uso de los anticuerpos y las terapias de combinación
|
|
EP3810116B1
(en)
|
2018-05-31 |
2023-11-15 |
Merck Sharp & Dohme LLC |
Novel substituted [1.1.1] bicyclo compounds as indoleamine 2,3-dioxygenase inhibitors
|
|
US12331068B2
(en)
|
2018-05-31 |
2025-06-17 |
Peloton Therapeutics, Inc. |
Compositions and methods for inhibiting CD73
|
|
JP7490574B2
(ja)
|
2018-05-31 |
2024-05-27 |
ノバルティス アーゲー |
B型肝炎抗体
|
|
US20210214459A1
(en)
|
2018-05-31 |
2021-07-15 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
|
SG11202011651SA
(en)
|
2018-05-31 |
2020-12-30 |
Ono Pharmaceutical Co |
Biomarkers for determining the effectiveness of immune checkpoint inhibitors
|
|
EP3818085A4
(en)
*
|
2018-06-01 |
2022-03-09 |
Tayu Huaxia Biotech Medical Group Co., Ltd. |
COMPOSITIONS AND THEIR USES FOR TREATING A DISEASE OR CONDITION
|
|
US20210205449A1
(en)
|
2018-06-01 |
2021-07-08 |
Novartis Ag |
Dosing of a bispecific antibody that bind cd123 and cd3
|
|
WO2019227490A1
(en)
*
|
2018-06-01 |
2019-12-05 |
Tayu Huaxia Biotech Medical Group Co., Ltd. |
Compositions and methods for imaging
|
|
CA3102097A1
(en)
|
2018-06-01 |
2019-12-05 |
The Board Of Trustees Of The Leland Stanford Junior Unversity |
Il-13/il-4 superkines: immune cell targeting constructs and methods of use thereof
|
|
CA3098420A1
(en)
|
2018-06-01 |
2019-12-05 |
Novartis Ag |
Binding molecules against bcma and uses thereof
|
|
CA3102398A1
(en)
|
2018-06-03 |
2019-12-12 |
Lamkap Bio Beta Ltd. |
Bispecific antibodies against ceacam5 and cd47
|
|
CN110563842B
(zh)
|
2018-06-06 |
2022-07-29 |
浙江博锐生物制药有限公司 |
针对程序性死亡配体(pd-l1)的抗体及其应用
|
|
MX2020013443A
(es)
|
2018-06-13 |
2021-02-26 |
Novartis Ag |
Receptores de antigeno quimerico de bcma y usos de los mismos.
|
|
EP3806848A2
(en)
|
2018-06-15 |
2021-04-21 |
Flagship Pioneering Innovations V, Inc. |
Increasing immune activity through modulation of postcellular signaling factors
|
|
CN112334486B
(zh)
|
2018-06-18 |
2025-02-18 |
先天制药公司 |
用于治疗癌症的组合物和方法
|
|
US20210347842A1
(en)
|
2018-06-19 |
2021-11-11 |
Eli Lilly And Company |
Compositions and methods of use of il-10 agents in conjunction with chimeric antigen receptor cell therapy
|
|
JP2021527714A
(ja)
|
2018-06-20 |
2021-10-14 |
インサイト・コーポレイションIncyte Corporation |
抗pd−1抗体及びその使用
|
|
EP3810615A4
(en)
|
2018-06-20 |
2022-03-30 |
Merck Sharp & Dohme Corp. |
ARGINASE INHIBITORS AND METHODS OF USE
|
|
US11180531B2
(en)
|
2018-06-22 |
2021-11-23 |
Bicycletx Limited |
Bicyclic peptide ligands specific for Nectin-4
|
|
TWI890148B
(zh)
|
2018-06-23 |
2025-07-11 |
美商建南德克公司 |
以pd-1軸結合拮抗劑、鉑劑及拓撲異構酶ii抑制劑治療肺癌之方法
|
|
HUE064531T2
(hu)
|
2018-06-27 |
2024-04-28 |
Bristol Myers Squibb Co |
Szubsztituált naftiridinon vegyületek mint T-sejt aktivátorok
|
|
DK3814347T3
(da)
|
2018-06-27 |
2023-08-07 |
Bristol Myers Squibb Co |
Naphthyridinonforbindelse, der er nyttige som t-celleaktivatorer
|
|
CN112955465A
(zh)
|
2018-07-03 |
2021-06-11 |
马伦戈治疗公司 |
抗tcr抗体分子及其用途
|
|
GEP20237560B
(en)
|
2018-07-05 |
2023-10-25 |
Incyte Corp |
Fused pyrazine derivatives as a2a / a2b inhibitors
|
|
EP3817748A4
(en)
|
2018-07-06 |
2022-08-24 |
Kymera Therapeutics, Inc. |
TRICYCLIC CRBN LIGANDS AND USES THEREOF
|
|
WO2020010227A1
(en)
|
2018-07-06 |
2020-01-09 |
Kymera Therapeutics, Inc. |
Protein degraders and uses thereof
|
|
CN112424167A
(zh)
|
2018-07-09 |
2021-02-26 |
葛兰素史密斯克莱知识产权发展有限公司 |
化学化合物
|
|
TW202428604A
(zh)
|
2018-07-09 |
2024-07-16 |
美商戊瑞治療有限公司 |
結合至ilt4的抗體
|
|
TW202035448A
(zh)
*
|
2018-07-09 |
2020-10-01 |
中國大陸商上海岸邁生物科技有限公司 |
有效表現之egfr及pd-l1雙特異性結合蛋白
|
|
CA3103385A1
(en)
|
2018-07-10 |
2020-01-16 |
Novartis Ag |
3-(5-hydroxy-1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and their use in the treatment of ikaros family zinc finger 2 (ikzf2)-dependent diseases
|
|
AR116109A1
(es)
|
2018-07-10 |
2021-03-31 |
Novartis Ag |
Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos
|
|
AU2019301699C1
(en)
|
2018-07-11 |
2024-10-10 |
Actym Therapeutics, Inc. |
Engineered immunostimulatory bacterial strains and uses thereof
|
|
US12091462B2
(en)
|
2018-07-11 |
2024-09-17 |
Five Prime Therapeutics, Inc. |
Antibodies binding to vista at acidic pH
|
|
GB201811410D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Beta Ltd |
OX40 Binding molecules
|
|
EP3820898B1
(en)
|
2018-07-12 |
2025-09-03 |
invoX Pharma Limited |
Antibody molecules that bind cd137 and ox40
|
|
GB201811450D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Delta Ltd |
Mesothelin and CD137 binding molecules
|
|
GB201811403D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Beta Ltd |
Antibody molecules
|
|
GB201811408D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Beta Ltd |
CD137 Binding Molecules
|
|
GB201811415D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Beta Ltd |
Anti-Mesothelin Anti bodies
|
|
US12344672B2
(en)
|
2018-07-12 |
2025-07-01 |
Invox Pharma Limited |
Antibody molecules that bind PD-L1 and CD137
|
|
KR102530517B1
(ko)
|
2018-07-13 |
2023-05-09 |
알렉터 엘엘씨 |
항-소틸린 항체 및 이들의 사용 방법
|
|
US20210277135A1
(en)
|
2018-07-13 |
2021-09-09 |
Bristol-Myers Squibb Company |
Ox-40 agonist, pd-1 pathway inhibitor and ctla-4 inhibitor combination for use in a method of treating a cancer or a solid tumor
|
|
EP3820572B1
(en)
|
2018-07-13 |
2023-08-16 |
Gilead Sciences, Inc. |
Pd-1/pd-l1 inhibitors
|
|
JP7522720B2
(ja)
|
2018-07-18 |
2024-07-25 |
アーカス バイオサイエンシズ インコーポレイティド |
アゾロピリミジン化合物の固体形態
|
|
CN112839644A
(zh)
|
2018-07-18 |
2021-05-25 |
豪夫迈·罗氏有限公司 |
用pd-1轴结合拮抗剂、抗代谢物和铂剂治疗肺癌的方法
|
|
EP3823673A4
(en)
|
2018-07-20 |
2022-05-11 |
Surface Oncology, Inc. |
Anti-cd112r compositions and methods
|
|
US12059420B2
(en)
|
2018-07-23 |
2024-08-13 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
|
WO2020023356A1
(en)
|
2018-07-23 |
2020-01-30 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
|
CN112601584A
(zh)
|
2018-07-24 |
2021-04-02 |
豪夫迈·罗氏有限公司 |
异喹啉化合物及其用途
|
|
JP7386842B2
(ja)
|
2018-07-24 |
2023-11-27 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
ナフチリジン化合物およびその使用
|
|
EP3827020A1
(en)
|
2018-07-24 |
2021-06-02 |
Amgen Inc. |
Combination of lilrb1/2 pathway inhibitors and pd-1 pathway inhibitors
|
|
CN112041348B
(zh)
|
2018-07-25 |
2023-09-22 |
天境生物科技(上海)有限公司 |
抗cd73抗pd-l1双特异性抗体
|
|
JP2021530243A
(ja)
|
2018-07-25 |
2021-11-11 |
アスクジーン・ファーマ・インコーポレイテッドAskGene Pharma, Inc. |
新規il−21プロドラッグおよびそれを使用する方法
|
|
US20210238287A1
(en)
|
2018-07-26 |
2021-08-05 |
Bristol-Myers Squibb Company |
LAG-3 Combination Therapy for the Treatment of Cancer
|
|
WO2020021061A1
(en)
|
2018-07-26 |
2020-01-30 |
Pieris Pharmaceuticals Gmbh |
Humanized anti-pd-1 antibodies and uses thereof
|
|
US11554120B2
(en)
|
2018-08-03 |
2023-01-17 |
Bristol-Myers Squibb Company |
1H-pyrazolo[4,3-d]pyrimidine compounds as toll-like receptor 7 (TLR7) agonists and methods and uses therefor
|
|
US20210236633A1
(en)
|
2018-08-06 |
2021-08-05 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating cancers
|
|
WO2020031107A1
(en)
|
2018-08-08 |
2020-02-13 |
Glaxosmithkline Intellectual Property Development Limited |
Chemical compounds
|
|
JP2021534101A
(ja)
|
2018-08-09 |
2021-12-09 |
ヴェルソー セラピューティクス, インコーポレイテッド |
Ccr2及びcsf1rを標的とするためのオリゴヌクレオチド組成物ならびにその使用
|
|
CN113307872B
(zh)
*
|
2018-08-11 |
2022-12-06 |
广东天科雅生物医药科技有限公司 |
一种工程化核酸、t细胞及其应用和产生方法
|
|
ES2930171T3
(es)
|
2018-08-16 |
2022-12-07 |
Innate Tumor Immunity Inc |
Moduladores de NLRP3 derivados de imidazo[4,5-C]quinolina
|
|
EP3837015B1
(en)
|
2018-08-16 |
2024-02-14 |
Innate Tumor Immunity, Inc. |
Imidazo[4,5-c]quinoline derived nlrp3-modulators
|
|
WO2020037094A1
(en)
|
2018-08-16 |
2020-02-20 |
Innate Tumor Immunity, Inc. |
Substitued 4-amino-1h-imidazo[4,5-c]quinoline compounds and improved methods for their preparation
|
|
AU2019324388A1
(en)
*
|
2018-08-20 |
2021-03-18 |
1Globe Biomedical Co., Ltd. |
Novel cancer immunotherapy antibody compositions
|
|
CA3106881A1
(en)
|
2018-08-27 |
2020-03-05 |
Pieris Pharmaceuticals Gmbh |
Combination therapies comprising cd137/her2 bispecific agents and pd-1 axis inhibitors and uses thereof
|
|
WO2020044206A1
(en)
|
2018-08-29 |
2020-03-05 |
Glaxosmithkline Intellectual Property Development Limited |
Heterocyclic amides as kinase inhibitors for use in the treatment cancer
|
|
US11253525B2
(en)
|
2018-08-29 |
2022-02-22 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
|
US10959986B2
(en)
|
2018-08-29 |
2021-03-30 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
|
TW202031273A
(zh)
|
2018-08-31 |
2020-09-01 |
美商艾歐凡斯生物治療公司 |
抗pd-1抗體難治療性之非小細胞肺癌(nsclc)病患的治療
|
|
US20210340279A1
(en)
|
2018-08-31 |
2021-11-04 |
Yale University |
Compositions and methods of using cell-penetrating antibodies in combination with immune checkpoint modulators
|
|
JP7535500B2
(ja)
|
2018-09-03 |
2024-08-16 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
Teadモジュレーターとして有用なカルボキサミドおよびスルホンアミド誘導体
|
|
WO2020048942A1
(en)
|
2018-09-04 |
2020-03-12 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for enhancing cytotoxic t lymphocyte-dependent immune responses
|
|
AU2019336197A1
(en)
|
2018-09-07 |
2021-02-18 |
Pfizer Inc. |
Anti-avb8 antibodies and compositions and uses thereof
|
|
WO2020051424A1
(en)
|
2018-09-07 |
2020-03-12 |
Pic Therapeutics |
Eif4e inhibitors and uses thereof
|
|
WO2020053742A2
(en)
|
2018-09-10 |
2020-03-19 |
Novartis Ag |
Anti-hla-hbv peptide antibodies
|
|
EA202190748A1
(ru)
|
2018-09-11 |
2021-07-22 |
Кьюрис Инк. |
Комбинированная терапия ингибитором фосфоинозитид-3-киназы с цинк-связывающей группировкой
|
|
WO2020056194A1
(en)
|
2018-09-12 |
2020-03-19 |
Silverback Therapeutics, Inc. |
Benzazepine compounds, conjugates, and uses thereof
|
|
WO2020053654A1
(en)
|
2018-09-12 |
2020-03-19 |
Novartis Ag |
Antiviral pyridopyrazinedione compounds
|
|
AU2019337652A1
(en)
|
2018-09-12 |
2021-03-18 |
Silverback Therapeutics, Inc. |
Antibody conjugates of toll-like receptor agonists
|
|
KR20210081332A
(ko)
|
2018-09-12 |
2021-07-01 |
실버백 테라퓨틱스, 인크. |
면역 자극성 접합체를 사용한 질환의 치료를 위한 조성물
|
|
CN113166113A
(zh)
|
2018-09-12 |
2021-07-23 |
希沃尔拜克治疗公司 |
取代的苯并氮杂䓬化合物、缀合物及其用途
|
|
AU2019337547A1
(en)
|
2018-09-13 |
2021-03-18 |
Merck Sharp & Dohme Llc |
Combination of PD-1 antagonist and LAG3 antagonist for treating non-microsatellite instablity-high/proficient mismatch repair colorectal cancer
|
|
EP3853611A1
(en)
|
2018-09-19 |
2021-07-28 |
F. Hoffmann-La Roche AG |
Therapeutic and diagnostic methods for bladder cancer
|
|
KR20210089146A
(ko)
|
2018-09-19 |
2021-07-15 |
알파인 이뮨 사이언시즈, 인코포레이티드 |
변이체 cd80 단백질 및 관련 구축물의 방법 및 용도
|
|
CN113015526A
(zh)
|
2018-09-19 |
2021-06-22 |
豪夫迈·罗氏有限公司 |
螺环2,3-二氢-7-氮杂吲哚化合物及其用途
|
|
JP7618950B2
(ja)
|
2018-09-19 |
2025-01-22 |
インサーム (インスティテュート ナショナル デ ラ サンテ エ デ ラ ルシェルシェ メディカル) |
免疫チェックポイント治療に抵抗性のある癌の治療のための方法および医薬組成物
|
|
CA3112599A1
(en)
|
2018-09-20 |
2020-03-26 |
Iovance Biotherapeutics, Inc. |
Expansion of tils from cryopreserved tumor samples
|
|
MX2021003213A
(es)
|
2018-09-21 |
2021-05-12 |
Genentech Inc |
Metodos de diagnostico para cancer de mama triple negativo.
|
|
US12195544B2
(en)
|
2018-09-21 |
2025-01-14 |
Harpoon Therapeutics, Inc. |
EGFR binding proteins and methods of use
|
|
IL297931B2
(en)
|
2018-09-25 |
2025-03-01 |
Harpoon Therapeutics Inc |
DLL3 binding proteins and methods of use
|
|
CN113286614A
(zh)
|
2018-09-26 |
2021-08-20 |
默克专利股份有限公司 |
用于治疗癌症的pd-1拮抗剂、atr抑制剂和铂化物质的组合
|
|
JP7465272B2
(ja)
|
2018-09-27 |
2024-04-10 |
マレンゴ・セラピューティクス,インコーポレーテッド |
Csf1r/ccr2多特異性抗体
|
|
US20210347851A1
(en)
|
2018-09-28 |
2021-11-11 |
Novartis Ag |
Cd19 chimeric antigen receptor (car) and cd22 car combination therapies
|
|
WO2020069405A1
(en)
|
2018-09-28 |
2020-04-02 |
Novartis Ag |
Cd22 chimeric antigen receptor (car) therapies
|
|
US20200102370A1
(en)
|
2018-09-28 |
2020-04-02 |
Massachusetts Institute Of Technology |
Collagen-localized immunomodulatory molecules and methods thereof
|
|
KR102820455B1
(ko)
|
2018-09-29 |
2025-06-16 |
노파르티스 아게 |
Shp2 활성 억제용 화합물의 제조 방법
|
|
EP3856724A1
(en)
|
2018-09-30 |
2021-08-04 |
F. Hoffmann-La Roche AG |
Cinnoline compounds and for the treatment of hpk1-dependent disorders such as cancer
|
|
EP3860578A1
(en)
|
2018-10-01 |
2021-08-11 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Use of inhibitors of stress granule formation for targeting the regulation of immune responses
|
|
TW202024053A
(zh)
|
2018-10-02 |
2020-07-01 |
美商建南德克公司 |
異喹啉化合物及其用途
|
|
CN113166062A
(zh)
|
2018-10-03 |
2021-07-23 |
豪夫迈·罗氏有限公司 |
8-氨基异喹啉化合物及其用途
|
|
MA53822A
(fr)
|
2018-10-03 |
2021-08-11 |
Xencor Inc |
Protéines de fusion fc hétérodimères d'il -12
|
|
JP2022512642A
(ja)
|
2018-10-09 |
2022-02-07 |
ブリストル-マイヤーズ スクイブ カンパニー |
がんを治療するための抗MerTK抗体
|
|
US11066404B2
(en)
|
2018-10-11 |
2021-07-20 |
Incyte Corporation |
Dihydropyrido[2,3-d]pyrimidinone compounds as CDK2 inhibitors
|
|
TW202446772A
(zh)
|
2018-10-11 |
2024-12-01 |
日商小野藥品工業股份有限公司 |
Sting促效化合物
|
|
WO2020077170A1
(en)
|
2018-10-12 |
2020-04-16 |
University Of Pittsburgh- Of The Commonwealth System Of Higher Education |
Small polymeric carriers for delivery of agents
|
|
PE20211055A1
(es)
|
2018-10-12 |
2021-06-07 |
Xencor Inc |
Proteinas de fusion il-15 / il-15 ralpha f c dirigidas a pd-1 y usos en terapias de combinacion de las mismas
|
|
US20210348238A1
(en)
|
2018-10-16 |
2021-11-11 |
Novartis Ag |
Tumor mutation burden alone or in combination with immune markers as biomarkers for predicting response to targeted therapy
|
|
WO2020081493A1
(en)
|
2018-10-16 |
2020-04-23 |
Molecular Templates, Inc. |
Pd-l1 binding proteins
|
|
WO2020081381A1
(en)
|
2018-10-17 |
2020-04-23 |
Merck Sharp & Dohme Corp. |
Novel arylalkyl pyrazole compounds as indoleamine 2,3-dioxygenase inhibitors
|
|
EP3867269A1
(en)
|
2018-10-18 |
2021-08-25 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Combination of a big-h3 antagonist and an immune checkpoint inhibitor for the treatment of solid tumor
|
|
EP3867646A1
(en)
|
2018-10-18 |
2021-08-25 |
F. Hoffmann-La Roche AG |
Diagnostic and therapeutic methods for sarcomatoid kidney cancer
|
|
LT3866850T
(lt)
|
2018-10-19 |
2024-09-10 |
Bristol-Myers Squibb Company |
Kompleksinė melanomos terapija
|
|
US20210324081A1
(en)
|
2018-10-22 |
2021-10-21 |
Glaxosmithkline Intellectual Property Development Limited |
Dosing
|
|
EP3870609A1
(en)
|
2018-10-23 |
2021-09-01 |
Bristol-Myers Squibb Company |
Methods of treating tumor
|
|
EP3870598A1
(en)
|
2018-10-23 |
2021-09-01 |
Dragonfly Therapeutics, Inc. |
Heterodimeric fc-fused proteins
|
|
AU2019366355B2
(en)
|
2018-10-24 |
2022-10-13 |
Gilead Sciences, Inc. |
PD-1/PD-L1 inhibitors
|
|
CN113365664A
(zh)
|
2018-10-29 |
2021-09-07 |
梅尔莎纳医疗公司 |
具有含肽接头的半胱氨酸工程化的抗体-药物缀合物
|
|
AU2019369299A1
(en)
|
2018-10-29 |
2021-05-20 |
Wisconsin Alumni Research Foundation |
Dendritic polymers complexed with immune checkpoint inhibitors for enhanced cancer immunotherapy
|
|
US11564995B2
(en)
|
2018-10-29 |
2023-01-31 |
Wisconsin Alumni Research Foundation |
Peptide-nanoparticle conjugates
|
|
EP3873532A1
(en)
|
2018-10-31 |
2021-09-08 |
Novartis AG |
Dc-sign antibody drug conjugates
|
|
BR112021007626A2
(pt)
|
2018-11-01 |
2021-10-13 |
Juno Therapeutics, Inc. |
Receptores antigênicos quiméricos específicos pa-ra receptor acoplado à proteína g receptor de classe c, grupo 5, membro d (gprc5d)
|
|
EP3873464B1
(en)
|
2018-11-01 |
2025-07-30 |
Merck Sharp & Dohme LLC |
Novel substituted pyrazole compounds as indoleamine 2,3-dioxygenase inhibitors
|
|
SG11202104188VA
(en)
|
2018-11-01 |
2021-05-28 |
Juno Therapeutics Inc |
Methods for treatment using chimeric antigen receptors specific for b-cell maturation antigen
|
|
SG11202104615VA
(en)
|
2018-11-05 |
2021-06-29 |
Iovance Biotherapeutics Inc |
Processes for production of tumor infiltrating lymphocytes and uses of the same in immunotherapy
|
|
SG11202104630PA
(en)
|
2018-11-05 |
2021-06-29 |
Iovance Biotherapeutics Inc |
Selection of improved tumor reactive t-cells
|
|
US12065438B2
(en)
|
2018-11-06 |
2024-08-20 |
Merck Sharp & Dohme Llc |
Substituted tricyclic compounds as indoleamine 2,3-dioxygenase inhibitors
|
|
WO2020094744A1
(en)
|
2018-11-06 |
2020-05-14 |
Genmab A/S |
Antibody formulation
|
|
WO2020097409A2
(en)
|
2018-11-08 |
2020-05-14 |
Modernatx, Inc. |
Use of mrna encoding ox40l to treat cancer in human patients
|
|
US12410225B2
(en)
|
2018-11-08 |
2025-09-09 |
Orionis Biosciences, Inc |
Modulation of dendritic cell lineages
|
|
CN120594829A
(zh)
|
2018-11-09 |
2025-09-05 |
皮埃里亚生物科学有限责任公司 |
用于测定肿瘤微环境组成的方法和组合物
|
|
TWI840442B
(zh)
|
2018-11-13 |
2024-05-01 |
美商坎伯斯治療有限責任公司 |
對抗檢查點分子之多特異性結合構築體及其用途
|
|
WO2020099230A1
(en)
|
2018-11-14 |
2020-05-22 |
Bayer Aktiengesellschaft |
Pharmaceutical combination of anti-ceacam6 and either anti-pd-1 or anti-pd-l1 antibodies for the treatment of cancer
|
|
HUE067601T2
(hu)
|
2018-11-14 |
2024-10-28 |
Regeneron Pharma |
PD-1 inhibitorok intraléziós beadása a bõrrák kezelésére
|
|
TW202028222A
(zh)
|
2018-11-14 |
2020-08-01 |
美商Ionis製藥公司 |
Foxp3表現之調節劑
|
|
NZ777032A
(en)
|
2018-11-16 |
2024-07-26 |
Bristol Myers Squibb Co |
Anti-nkg2a antibodies and uses thereof
|
|
WO2020102646A2
(en)
|
2018-11-16 |
2020-05-22 |
Arcus Biosciences, Inc. |
Inhibitors of arg1 and/or arg2
|
|
BR112021009411A2
(pt)
|
2018-11-16 |
2021-08-17 |
Arqule, Inc. |
combinação farmacêutica para tratamento de câncer
|
|
JP2022507606A
(ja)
|
2018-11-16 |
2022-01-18 |
ネオイミューンテック, インコーポレイテッド |
Il-7タンパク質と免疫チェックポイント阻害剤の組み合わせで腫瘍を治療する方法
|
|
SG11202105084VA
(en)
|
2018-11-16 |
2021-06-29 |
Juno Therapeutics Inc |
Methods of dosing engineered t cells for the treatment of b cell malignancies
|
|
WO2020104496A1
(en)
|
2018-11-20 |
2020-05-28 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Bispecific antibody targeting transferrin receptor 1 and soluble antigen
|
|
WO2020104479A1
(en)
|
2018-11-20 |
2020-05-28 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating cancers and resistant cancers with anti transferrin receptor 1 antibodies
|
|
CA3119774A1
(en)
|
2018-11-20 |
2020-05-28 |
Merck Sharp & Dohme Corp. |
Substituted amino triazolopyrimidine and amino triazolopyrazine adenosine receptor antagonists, pharmaceutical compositions and their use
|
|
US12414952B2
(en)
|
2018-11-20 |
2025-09-16 |
Merck Sharp & Dohme Llc |
Substituted amino triazolopyrimidine and amino triazolopyrazine adenosine receptor antagonists, pharmaceutical compositions and their use
|
|
JP2022511437A
(ja)
|
2018-11-26 |
2022-01-31 |
デバイオファーム インターナショナル エス.エー. |
Hiv感染の組み合わせ治療
|
|
WO2020111018A1
(ja)
|
2018-11-27 |
2020-06-04 |
小野薬品工業株式会社 |
免疫チェックポイント阻害薬およびfolfirinox療法との併用によるがん治療
|
|
EP3887397A1
(en)
|
2018-11-28 |
2021-10-06 |
Bristol-Myers Squibb Company |
Antibodies comprising modified heavy constant regions
|
|
US20220018828A1
(en)
|
2018-11-28 |
2022-01-20 |
Inserm (Institut National De La Santé Et La Recherche Médicale |
Methods and kit for assaying lytic potential of immune effector cells
|
|
EP3886845B1
(en)
|
2018-11-28 |
2024-09-04 |
Merck Sharp & Dohme LLC |
Novel substituted piperazine amide compounds as indoleamine 2, 3-dioxygenase (ido) inhibitors
|
|
SG11202105424PA
(en)
|
2018-11-30 |
2021-06-29 |
Kymera Therapeutics Inc |
Irak degraders and uses thereof
|
|
FI3886875T3
(fi)
|
2018-11-30 |
2024-07-23 |
Juno Therapeutics Inc |
Adoptiivista soluterapiaa käyttäviä hoitomenetelmiä
|
|
JOP20210117A1
(ar)
|
2018-11-30 |
2023-01-30 |
Merck Sharp & Dohme |
مشتقات أمينو ترايازولو كوينازولين بها استبدال في الموضع-9 كمضادات مستقبل أدينوزين، تركيبات صيدلانية واستخدامها
|
|
AU2019386945B9
(en)
|
2018-11-30 |
2025-10-23 |
Bristol-Myers Squibb Company |
Antibody comprising a glutamine-containing light chain C-terminal extension, conjugates thereof, and methods and uses
|
|
CA3121140A1
(en)
|
2018-11-30 |
2020-06-04 |
Glaxosmithkline Intellectual Property Development Limited |
Compounds useful in hiv therapy
|
|
CN113677364B
(zh)
|
2018-12-03 |
2024-07-05 |
艾更斯司股份有限公司 |
包含抗191p4d12抗体药物偶联物的药物组合物及其使用方法
|
|
EP3891508A1
(en)
|
2018-12-04 |
2021-10-13 |
Bristol-Myers Squibb Company |
Methods of analysis using in-sample calibration curve by multiple isotopologue reaction monitoring
|
|
KR20210099066A
(ko)
|
2018-12-04 |
2021-08-11 |
스미토모 다이니폰 파마 온콜로지, 인크. |
암의 치료를 위한 작용제로서 사용하기 위한 cdk9 억제제 및 그의 다형체
|
|
WO2020117952A2
(en)
|
2018-12-05 |
2020-06-11 |
Genentech, Inc. |
Diagnostic methods and compositions for cancer immunotherapy
|
|
US20220018835A1
(en)
|
2018-12-07 |
2022-01-20 |
INSERM (Institut National de la Santé et de la Recherche Médicale |
Use of cd26 and cd39 as new phenotypic markers for assessing maturation of foxp3+ t cells and uses thereof for diagnostic purposes
|
|
WO2020115261A1
(en)
|
2018-12-07 |
2020-06-11 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma
|
|
US10952996B2
(en)
|
2018-12-11 |
2021-03-23 |
Theravance Biopharma R&D Ip, Llc |
ALK5 inhibitors
|
|
KR20210102334A
(ko)
|
2018-12-12 |
2021-08-19 |
브리스톨-마이어스 스큅 컴퍼니 |
트랜스글루타미나제 접합을 위해 변형된 항체, 그의 접합체, 및 방법 및 용도
|
|
WO2020120592A1
(en)
|
2018-12-12 |
2020-06-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for predicting and treating melanoma
|
|
GB201820295D0
(en)
|
2018-12-13 |
2019-01-30 |
Bicyclerd Ltd |
Bicyclic peptide ligands specific for MT1-MMP
|
|
BR112021011393A2
(pt)
|
2018-12-13 |
2021-08-31 |
Surface Oncology, Inc. |
Anticorpos anti-il-27 e usos dos mesmos
|
|
GB201820325D0
(en)
|
2018-12-13 |
2019-01-30 |
Bicyclerd Ltd |
Bicyclic peptide ligands specific for psma
|
|
GB201820288D0
(en)
|
2018-12-13 |
2019-01-30 |
Bicycle Tx Ltd |
Bicycle peptide ligaands specific for MT1-MMP
|
|
WO2020127059A1
(en)
|
2018-12-17 |
2020-06-25 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of sulconazole as a furin inhibitor
|
|
US12240867B2
(en)
|
2018-12-18 |
2025-03-04 |
Merck Sharp & Dohme Llc |
Arginase inhibitors and methods of use
|
|
SG11202104518WA
(en)
|
2018-12-19 |
2021-05-28 |
Bayer Ag |
Pharmaceutical combination of anti ceacam6 and tim3 antibodies
|
|
EP3898699A1
(en)
|
2018-12-19 |
2021-10-27 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating cancers by immuno-modulation using antibodies against cathespin-d
|
|
JP2022514315A
(ja)
|
2018-12-20 |
2022-02-10 |
ノバルティス アーゲー |
3-(1-オキソイソインドリン-2-イル)ピペリジン-2,6-ジオン誘導体を含む投与計画及び薬剤組み合わせ
|
|
EP3670659A1
(en)
|
2018-12-20 |
2020-06-24 |
Abivax |
Biomarkers, and uses in treatment of viral infections, inflammations, or cancer
|
|
WO2020132646A1
(en)
|
2018-12-20 |
2020-06-25 |
Xencor, Inc. |
Targeted heterodimeric fc fusion proteins containing il-15/il-15ra and nkg2d antigen binding domains
|
|
AU2019409132A1
(en)
|
2018-12-21 |
2021-07-15 |
Novartis Ag |
Antibodies to PMEL17 and conjugates thereof
|
|
KR20210109564A
(ko)
|
2018-12-21 |
2021-09-06 |
옹쎄오 |
신규의 컨쥬게이티드 핵산 분자 및 이의 용도
|
|
WO2020127885A1
(en)
|
2018-12-21 |
2020-06-25 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Compositions for treating cancers and resistant cancers
|
|
KR20210107730A
(ko)
|
2018-12-21 |
2021-09-01 |
노파르티스 아게 |
골수 형성이상 증후군의 치료 또는 예방에서의 il-1 베타 항체의 용도
|
|
AU2019409139A1
(en)
|
2018-12-21 |
2021-06-03 |
Novartis Ag |
Use of IL-1β binding antibodies
|
|
US20220370606A1
(en)
|
2018-12-21 |
2022-11-24 |
Pfizer Inc. |
Combination Treatments Of Cancer Comprising A TLR Agonist
|
|
US20220025036A1
(en)
|
2018-12-21 |
2022-01-27 |
Novartis Ag |
Use of il-1beta binding antibodies
|
|
WO2020128526A1
(en)
|
2018-12-21 |
2020-06-25 |
Bicycletx Limited |
Bicyclic peptide ligands specific for pd-l1
|
|
WO2020128637A1
(en)
|
2018-12-21 |
2020-06-25 |
Novartis Ag |
Use of il-1 binding antibodies in the treatment of a msi-h cancer
|
|
BR112021012688A2
(pt)
*
|
2018-12-27 |
2021-09-08 |
Gigagen, Inc. |
Proteínas de ligação anti-pd-l1 e métodos de uso das mesmas
|
|
EP3902529A1
(en)
|
2018-12-27 |
2021-11-03 |
Amgen Inc. |
Lyophilized virus formulations
|
|
BR112021013157A8
(pt)
|
2019-01-03 |
2022-12-06 |
Inst Nat Sante Rech Med |
Usos de um inibidor de nrp-1, uso de uma combinação, uso de um anticorpo multiespecífico, método ex vivo para predizer, uso de um inibidor, anticorpo multiespecífico, população de células modificadas, método ex vivo de produção e uso de uma população de células t
|
|
AU2020205643C1
(en)
|
2019-01-09 |
2025-07-31 |
Celgene Corporation |
Antiproliferative compounds and second active agents for use in treating multiple myeloma
|
|
CN113597301A
(zh)
|
2019-01-09 |
2021-11-02 |
细胞基因公司 |
包含(s)-4-(4-(4-(((2-(2,6-二氧代哌啶-3-基)-1-氧代异吲哚啉-4-基)氧基)甲基)苄基)哌嗪-1-基)-3-氟苄腈的药物组合物以及使用它的方法
|
|
US11370777B2
(en)
|
2019-01-09 |
2022-06-28 |
Celgene Corporation |
Solid forms comprising (s)-4-(4-(4-(((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)oxy)methyl)benzyl)piperazin-1-yl)-3-fluorobenzonitrile and salts thereof, and compositions comprising and methods of using the same
|
|
KR102865929B1
(ko)
|
2019-01-14 |
2025-09-29 |
인네이트 튜머 이뮤니티, 인코포레이티드 |
Nlrp3 조정제
|
|
EP3911417B1
(en)
|
2019-01-14 |
2022-10-26 |
Innate Tumor Immunity, Inc. |
Heterocyclic nlrp3 modulators , for use in the treatment of cancer
|
|
JP7373571B2
(ja)
|
2019-01-14 |
2023-11-02 |
イネイト・テューマー・イミュニティ・インコーポレイテッド |
がん治療に用いるためのnlrp3モジュレーターとしての置換キナゾリン
|
|
KR20210114983A
(ko)
|
2019-01-14 |
2021-09-24 |
인네이트 튜머 이뮤니티, 인코포레이티드 |
Nlrp3 조정제
|
|
TW202515617A
(zh)
|
2019-01-14 |
2025-04-16 |
美商建南德克公司 |
用於癌症療法之rna分子
|
|
WO2020148338A1
(en)
|
2019-01-15 |
2020-07-23 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Mutated interleukin-34 (il-34) polypeptides and uses thereof in therapy
|
|
CA3123886A1
(en)
|
2019-01-17 |
2020-07-23 |
James DAHLMAN |
Drug delivery systems containing oxidized cholesterols
|
|
US11235032B2
(en)
|
2019-01-23 |
2022-02-01 |
Massachusetts Institute Of Technology |
Combination immunotherapy dosing regimen for immune checkpoint blockade
|
|
WO2020151572A1
(en)
|
2019-01-23 |
2020-07-30 |
Tayu Huaxia Biotech Medical Group Co., Ltd. |
Anti-pd-l1 diabodies and the use thereof
|
|
TWI829857B
(zh)
|
2019-01-29 |
2024-01-21 |
美商英塞特公司 |
作為a2a / a2b抑制劑之吡唑并吡啶及三唑并吡啶
|
|
MX2021009087A
(es)
|
2019-01-29 |
2021-09-08 |
Juno Therapeutics Inc |
Anticuerpos y receptores quimericos de antigenos especificos para receptor 1 huerfano tipo receptor tirosina-cinasa (ror1).
|
|
EP3918332B1
(en)
|
2019-01-30 |
2025-03-19 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for identifying whether a subject suffering from a cancer will achieve a response with an immune-checkpoint inhibitor
|
|
WO2020160365A1
(en)
|
2019-02-01 |
2020-08-06 |
Glaxosmithkline Intellectual Property Development Limited |
Belantamab mafodotin in combination with pembrolizumab for treating cancer
|
|
WO2020161083A1
(en)
|
2019-02-04 |
2020-08-13 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for modulating blood-brain barrier
|
|
WO2020163589A1
(en)
|
2019-02-08 |
2020-08-13 |
Genentech, Inc. |
Diagnostic and therapeutic methods for cancer
|
|
WO2020167990A1
(en)
|
2019-02-12 |
2020-08-20 |
Tolero Pharmaceuticals, Inc. |
Formulations comprising heterocyclic protein kinase inhibitors
|
|
WO2020165370A1
(en)
|
2019-02-13 |
2020-08-20 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for selecting a cancer treatment in a subject suffering from cancer
|
|
AU2020222346B2
(en)
|
2019-02-15 |
2021-12-09 |
Novartis Ag |
Substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
EP3924521A4
(en)
|
2019-02-15 |
2023-03-29 |
IncellDx, Inc. |
BLADDER-ASSOCIATED SAMPLES TESTING, IDENTIFICATION AND TREATMENT OF BLADDER-ASSOCIATED NEOPLASIA, AND KITS FOR USE THEREON
|
|
EP3924054B1
(en)
|
2019-02-15 |
2025-04-02 |
Novartis AG |
3-(1-oxo-5-(piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
WO2020168197A1
(en)
|
2019-02-15 |
2020-08-20 |
Incyte Corporation |
Pyrrolo[2,3-d]pyrimidinone compounds as cdk2 inhibitors
|
|
EP3923949A1
(en)
|
2019-02-15 |
2021-12-22 |
Incyte Corporation |
Cyclin-dependent kinase 2 biomarkers and uses thereof
|
|
WO2020169472A2
(en)
|
2019-02-18 |
2020-08-27 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods of inducing phenotypic changes in macrophages
|
|
EP3929213A4
(en)
*
|
2019-02-21 |
2023-03-08 |
Eucure (Beijing) Biopharma Co., Ltd |
ANTI-PD-L1 ANTIBODIES AND ITS USE
|
|
CN114026122B
(zh)
|
2019-02-21 |
2024-12-31 |
马伦戈治疗公司 |
结合t细胞相关癌细胞的多功能分子及其用途
|
|
CN119039441A
(zh)
|
2019-02-21 |
2024-11-29 |
马伦戈治疗公司 |
与nkp30结合的抗体分子及其用途
|
|
WO2020176771A1
(en)
|
2019-02-27 |
2020-09-03 |
Ionis Pharmaceuticals, Inc. |
Modulators of malat1 expression
|
|
JP2022521800A
(ja)
|
2019-02-28 |
2022-04-12 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
皮膚がんを治療するためのpd-1阻害剤の投与
|
|
JP7679303B2
(ja)
|
2019-03-05 |
2025-05-19 |
アムジエン・インコーポレーテツド |
がんを治療するための腫瘍溶解性ウイルスの使用
|
|
WO2020180959A1
(en)
|
2019-03-05 |
2020-09-10 |
Incyte Corporation |
Pyrazolyl pyrimidinylamine compounds as cdk2 inhibitors
|
|
US12187792B2
(en)
|
2019-03-06 |
2025-01-07 |
Regeneron Pharmaceuticals, Inc. |
IL-4/IL-13 pathway inhibitors for enhanced efficacy in treating cancer
|
|
US11628162B2
(en)
|
2019-03-08 |
2023-04-18 |
Incyte Corporation |
Methods of treating cancer with an FGFR inhibitor
|
|
CN113795267A
(zh)
|
2019-03-12 |
2021-12-14 |
艾库斯生物科学有限公司 |
致癌基因驱动的癌症的治疗
|
|
KR20210141555A
(ko)
|
2019-03-14 |
2021-11-23 |
제넨테크, 인크. |
Her2xcd3 이중특이적 항체 및 항-her2 mab를 병용한 암의 치료
|
|
JP7684947B2
(ja)
|
2019-03-19 |
2025-05-28 |
フンダシオ プリバダ インスティトゥト ディンベスティガシオ オンコロジカ デ バル エブロン |
癌の治療のための併用療法
|
|
US11793802B2
(en)
|
2019-03-20 |
2023-10-24 |
Sumitomo Pharma Oncology, Inc. |
Treatment of acute myeloid leukemia (AML) with venetoclax failure
|
|
KR20210141621A
(ko)
|
2019-03-22 |
2021-11-23 |
스미토모 다이니폰 파마 온콜로지, 인크. |
Pkm2 조정제를 포함하는 조성물 및 그를 사용한 치료 방법
|
|
JP2022526960A
(ja)
|
2019-03-28 |
2022-05-27 |
ブリストル-マイヤーズ スクイブ カンパニー |
腫瘍を処置する方法
|
|
JP2022527177A
(ja)
|
2019-03-28 |
2022-05-31 |
ブリストル-マイヤーズ スクイブ カンパニー |
腫瘍を処置する方法
|
|
TW202102543A
(zh)
|
2019-03-29 |
2021-01-16 |
美商安進公司 |
溶瘤病毒在癌症新輔助療法中之用途
|
|
WO2020205626A1
(en)
|
2019-03-29 |
2020-10-08 |
Genentech, Inc. |
Modulators of cell surface protein interactions and methods and compositions related to same
|
|
WO2020205560A1
(en)
|
2019-03-29 |
2020-10-08 |
Incyte Corporation |
Sulfonylamide compounds as cdk2 inhibitors
|
|
WO2020205527A1
(en)
|
2019-03-29 |
2020-10-08 |
Arcus Biosciences, Inc. |
Treatment of cancer utilizing an identified adenosine fingerprint
|
|
CN109929037B
(zh)
*
|
2019-04-01 |
2023-03-17 |
华博生物医药技术(上海)有限公司 |
针对程序性死亡配体的结合物及其应用
|
|
JP2022528887A
(ja)
|
2019-04-02 |
2022-06-16 |
バイスクルテクス・リミテッド |
バイシクルトキシンコンジュゲートおよびその使用
|
|
WO2020201362A2
(en)
|
2019-04-02 |
2020-10-08 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods of predicting and preventing cancer in patients having premalignant lesions
|
|
US12281109B2
(en)
|
2019-04-04 |
2025-04-22 |
Merck Sharp & Dohme Llc |
Inhibitors of histone deacetylase-3 useful for the treatment of cancer, inflammation, neurodegeneration diseases and diabetes
|
|
KR20220006139A
(ko)
|
2019-04-05 |
2022-01-14 |
카이메라 쎄라퓨틱스 인코포레이티드 |
Stat 분해제 및 이의 용도
|
|
US20220160692A1
(en)
|
2019-04-09 |
2022-05-26 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of sk2 inhibitors in combination with immune checkpoint blockade therapy for the treatment of cancer
|
|
EA202192800A1
(ru)
|
2019-04-12 |
2022-03-30 |
Васкулар Биодженикс Лтд |
Способы противоопухолевой терапии
|
|
EP3956446A1
(en)
|
2019-04-17 |
2022-02-23 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treatment of nlrp3 inflammasome mediated il-1beta dependent disorders
|
|
CA3136453A1
(en)
*
|
2019-04-18 |
2020-10-22 |
Qlsf Biotherapeutics Inc. |
Humanized anti-pd-l1 antibodies
|
|
CA3134522A1
(en)
|
2019-04-19 |
2020-10-22 |
Genentech, Inc. |
Anti-mertk antibodies and their methods of use
|
|
EP3725370A1
(en)
|
2019-04-19 |
2020-10-21 |
ImmunoBrain Checkpoint, Inc. |
Modified anti-pd-l1 antibodies and methods and uses for treating a neurodegenerative disease
|
|
AU2020260693A1
(en)
|
2019-04-23 |
2021-10-28 |
Innate Pharma |
CD73 blocking antibodies
|
|
WO2020223233A1
(en)
|
2019-04-30 |
2020-11-05 |
Genentech, Inc. |
Prognostic and therapeutic methods for colorectal cancer
|
|
WO2020221796A1
(en)
|
2019-04-30 |
2020-11-05 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma
|
|
US20200345820A1
(en)
|
2019-05-01 |
2020-11-05 |
Sensei Biotherapeutics, Inc. |
Combination therapies for cancer
|
|
WO2020223558A1
(en)
|
2019-05-01 |
2020-11-05 |
Incyte Corporation |
Tricyclic amine compounds as cdk2 inhibitors
|
|
WO2020223469A1
(en)
|
2019-05-01 |
2020-11-05 |
Incyte Corporation |
N-(1-(methylsulfonyl)piperidin-4-yl)-4,5-di hydro-1h-imidazo[4,5-h]quinazolin-8-amine derivatives and related compounds as cyclin-dependent kinase 2 (cdk2) inhibitors for treating cancer
|
|
MA55805A
(fr)
|
2019-05-03 |
2022-03-09 |
Flagship Pioneering Innovations V Inc |
Métodes de modulation de l'activité immunitaire
|
|
MX2021013222A
(es)
|
2019-05-03 |
2022-01-06 |
Genentech Inc |
Metodos para tratar el cancer con un anticuerpo anti-pd-l1.
|
|
WO2020225552A1
(en)
|
2019-05-06 |
2020-11-12 |
Medimmune Limited |
Combination of monalizumab, durvalumab, chemotherapy and bevacizumab or cetuximab for the treatment of colorectal cancer
|
|
WO2020226633A1
(en)
|
2019-05-07 |
2020-11-12 |
Immunicom, Inc. |
Increasing responses to checkpoint inhibitors by extracorporeal apheresis
|
|
JP2022533194A
(ja)
|
2019-05-16 |
2022-07-21 |
スティングセラ インコーポレイテッド |
ベンゾ[b][1,8]ナフチリジン酢酸誘導体および使用方法
|
|
CN114302875A
(zh)
|
2019-05-16 |
2022-04-08 |
斯汀塞拉股份有限公司 |
氧代吖啶基乙酸衍生物及使用方法
|
|
EP3972982A1
(en)
|
2019-05-20 |
2022-03-30 |
Massachusetts Institute of Technology |
Boronic ester prodrugs and uses thereof
|
|
CN113874036A
(zh)
|
2019-05-24 |
2021-12-31 |
辉瑞公司 |
使用cdk抑制剂的联合治疗
|
|
US20220363760A1
(en)
|
2019-05-30 |
2022-11-17 |
Bristol-Myers Squibb Company |
Multi-tumor gene signature for suitability to immuno-oncology therapy
|
|
KR20220016155A
(ko)
|
2019-05-30 |
2022-02-08 |
브리스톨-마이어스 스큅 컴퍼니 |
면역-종양학 (i-o) 요법에 적합한 대상체를 확인하는 방법
|
|
KR20220016157A
(ko)
|
2019-05-30 |
2022-02-08 |
브리스톨-마이어스 스큅 컴퍼니 |
세포 국재화 시그너쳐 및 조합 요법
|
|
CN114502540A
(zh)
|
2019-05-31 |
2022-05-13 |
医肯纳肿瘤学公司 |
Tead抑制剂和其用途
|
|
EP3929215A4
(en)
*
|
2019-06-10 |
2022-06-22 |
Shandong Boan Biotechnology Co., Ltd. |
BIFUNCTIONAL FUSION PROTEIN AGAINST PDL1 AND TGF? AND ITS USE
|
|
US12521438B2
(en)
|
2019-06-10 |
2026-01-13 |
Kymera Therapeutics, Inc. |
SMARCA degraders and uses thereof
|
|
US11246906B2
(en)
|
2019-06-11 |
2022-02-15 |
Alkermes Pharma Ireland Limited |
Compositions and methods for subcutaneous administration of cancer immunotherapy
|
|
WO2020248156A1
(zh)
*
|
2019-06-12 |
2020-12-17 |
苏州工业园区唯可达生物科技有限公司 |
Pd-l1靶向结合剂及其用途
|
|
CA3141626A1
(en)
|
2019-06-12 |
2020-12-17 |
AskGene Pharma, Inc. |
Novel il-15 prodrugs and methods of use thereof
|
|
WO2020255009A2
(en)
|
2019-06-18 |
2020-12-24 |
Janssen Sciences Ireland Unlimited Company |
Combination of hepatitis b virus (hbv) vaccines and anti-pd-1 antibody
|
|
CA3143680A1
(en)
|
2019-06-18 |
2020-12-24 |
Janssen Sciences Ireland Unlimited Company |
Combination of hepatitis b virus (hbv) vaccines and anti-pd-1 or anti-pd-l1 antibody
|
|
AU2020304112A1
(en)
|
2019-06-25 |
2022-01-27 |
Innovent Biologics (Suzhou) Co., Ltd. |
Formulations containing anti-CD47/PD-L1 bispecific antibody and preparation method therefor and use thereof
|
|
JP2022538974A
(ja)
|
2019-06-26 |
2022-09-07 |
マサチューセッツ インスチテュート オブ テクノロジー |
免疫調節融合タンパク質-金属水酸化物錯体およびその方法
|
|
EP3990494A1
(en)
|
2019-06-26 |
2022-05-04 |
GlaxoSmithKline Intellectual Property Development Limited |
Il1rap binding proteins
|
|
EP3990635A1
(en)
|
2019-06-27 |
2022-05-04 |
Rigontec GmbH |
Design method for optimized rig-i ligands
|
|
BR112021026832A2
(pt)
|
2019-07-02 |
2022-05-10 |
Hutchinson Fred Cancer Res |
Vetores ad35 recombinantes e aprimoramentos da terapia gênica relacionada
|
|
JP2022539208A
(ja)
|
2019-07-03 |
2022-09-07 |
スミトモ ファーマ オンコロジー, インコーポレイテッド |
チロシンキナーゼ非受容体1(tnk1)阻害剤およびその使用
|
|
US11591329B2
(en)
|
2019-07-09 |
2023-02-28 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
GB201910138D0
(en)
*
|
2019-07-15 |
2019-08-28 |
Capella Bioscience Ltd |
Anti-pd-l1 antibodies
|
|
GB201910305D0
(en)
|
2019-07-18 |
2019-09-04 |
Ctxt Pty Ltd |
Compounds
|
|
GB201910304D0
(en)
|
2019-07-18 |
2019-09-04 |
Ctxt Pty Ltd |
Compounds
|
|
US12036204B2
(en)
|
2019-07-26 |
2024-07-16 |
Eisai R&D Management Co., Ltd. |
Pharmaceutical composition for treating tumor
|
|
US11083705B2
(en)
|
2019-07-26 |
2021-08-10 |
Eisai R&D Management Co., Ltd. |
Pharmaceutical composition for treating tumor
|
|
US20220257698A1
(en)
|
2019-08-02 |
2022-08-18 |
Lanthiopep B.V. |
Angiotensin type 2 (at2) receptor agonists for use in the treatment of cancer
|
|
KR20220041099A
(ko)
|
2019-08-05 |
2022-03-31 |
오노 야꾸힝 고교 가부시키가이샤 |
면역 체크포인트 저해약의 유효성 판정 바이오마커
|
|
WO2021024020A1
(en)
|
2019-08-06 |
2021-02-11 |
Astellas Pharma Inc. |
Combination therapy involving antibodies against claudin 18.2 and immune checkpoint inhibitors for treatment of cancer
|
|
KR20220061977A
(ko)
|
2019-08-12 |
2022-05-13 |
퓨리노미아 바이오테크, 아이엔씨. |
Cd39 발현 세포의 adcc 표적화를 통해 t 세포 매개 면역 반응을 촉진 및 강화하기 위한 방법 및 조성물
|
|
TW202115024A
(zh)
|
2019-08-14 |
2021-04-16 |
美商英塞特公司 |
作為cdk2 抑制劑之咪唑基嘧啶基胺化合物
|
|
BR112022002720A2
(pt)
|
2019-08-15 |
2022-10-11 |
Silverback Therapeutics Inc |
Formulações de conjugados de benzazepinas e usos das mesmas
|
|
GB201912107D0
(en)
|
2019-08-22 |
2019-10-09 |
Amazentis Sa |
Combination
|
|
CN114341180B
(zh)
*
|
2019-08-23 |
2023-09-22 |
上海药明生物技术有限公司 |
抗pd-l1的人源化抗体
|
|
WO2021041532A1
(en)
|
2019-08-26 |
2021-03-04 |
Dana-Farber Cancer Institute, Inc. |
Use of heparin to promote type 1 interferon signaling
|
|
AR119821A1
(es)
|
2019-08-28 |
2022-01-12 |
Bristol Myers Squibb Co |
Compuestos de piridopirimidinonilo sustituidos útiles como activadores de células t
|
|
AU2020339478A1
(en)
*
|
2019-08-29 |
2021-05-06 |
Remegen Co., Ltd. |
Anti PD-L1 antibody and use thereof
|
|
MX2022002315A
(es)
|
2019-08-30 |
2022-03-25 |
Agenus Inc |
Anticuerpos anti-cd96 y sus metodos de uso.
|
|
WO2021043961A1
(en)
|
2019-09-06 |
2021-03-11 |
Glaxosmithkline Intellectual Property Development Limited |
Dosing regimen for the treatment of cancer with an anti icos agonistic antibody and chemotherapy
|
|
WO2021048292A1
(en)
|
2019-09-11 |
2021-03-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma
|
|
CA3150108A1
(en)
|
2019-09-13 |
2021-03-18 |
Neelu Kaila |
Hpk1 antagonists and uses thereof
|
|
JP2022548484A
(ja)
|
2019-09-16 |
2022-11-21 |
サーフィス オンコロジー インコーポレイテッド |
抗cd39抗体の組成物及び方法
|
|
US20240377413A1
(en)
|
2019-09-16 |
2024-11-14 |
Bristol-Myers Squibb Company |
Dual capture method for analysis of antibody-drug conjugates
|
|
EP4031531A1
(en)
|
2019-09-17 |
2022-07-27 |
Bial-R&D Investments, S.A. |
Substituted imidazole carboxamides and their use in the treatment of medical disorders
|
|
KR20220100860A
(ko)
|
2019-09-17 |
2022-07-18 |
비알 - 알&디 인베스트먼츠, 에스.에이. |
질병의 치료에 사용하기 위한 치환된, 포화 및 불포화 n-헤테로시클릭 카르복사미드 및 관련 화합물
|
|
CA3151022A1
(en)
|
2019-09-17 |
2021-03-25 |
Bial - R&D Investments, S.A. |
Substituted n-heterocyclic carboxamides as acid ceramidase inhibitors and their use as medicaments
|
|
TW202124445A
(zh)
|
2019-09-18 |
2021-07-01 |
瑞士商諾華公司 |
Nkg2d融合蛋白及其用途
|
|
JP2022548881A
(ja)
|
2019-09-18 |
2022-11-22 |
ノバルティス アーゲー |
Entpd2抗体、組合せ療法並びに抗体及び組合せ療法を使用する方法
|
|
TW202124446A
(zh)
|
2019-09-18 |
2021-07-01 |
瑞士商諾華公司 |
與entpd2抗體之組合療法
|
|
BR112022004995A2
(pt)
|
2019-09-18 |
2022-06-21 |
Lamkap Bio Alpha AG |
Anticorpos biespecíficos contra ceacam5 e cd3
|
|
CA3149621A1
(en)
|
2019-09-18 |
2021-03-25 |
Molecular Templates, Inc. |
Pd-l1 binding molecules comprising shiga toxin a subunit scaffolds
|
|
US11918649B2
(en)
|
2019-09-18 |
2024-03-05 |
Molecular Templates, Inc. |
PD-L1-binding molecules comprising Shiga toxin a subunit scaffolds
|
|
PE20220566A1
(es)
|
2019-09-19 |
2022-04-13 |
Bristol Myers Squibb Co |
ANTICUERPOS DE UNION A VISTA A pH ACIDO
|
|
JP7732977B2
(ja)
|
2019-09-20 |
2025-09-02 |
トランスジーン |
Hpvポリペプチドおよびil-2をコードするポックスウイルスと抗pd-l1抗体の組合せ
|
|
AU2020350795A1
(en)
|
2019-09-22 |
2022-03-31 |
Bristol-Myers Squibb Company |
Quantitative spatial profiling for LAG-3 antagonist therapy
|
|
JP2022549854A
(ja)
|
2019-09-25 |
2022-11-29 |
サーフィス オンコロジー インコーポレイテッド |
抗il-27抗体及びその使用
|
|
MX2022003487A
(es)
|
2019-09-25 |
2022-04-25 |
Bristol Myers Squibb Co |
Biomarcador compuesto para terapia de cancer.
|
|
CA3151928A1
(en)
*
|
2019-09-26 |
2021-04-01 |
Nikolai Kley |
Pd-l1 targeted chimeric proteins and uses thereof
|
|
AR120045A1
(es)
|
2019-09-26 |
2022-01-26 |
Novartis Ag |
Compuestos antivirales de pirazolopiridinona
|
|
CR20220127A
(es)
|
2019-09-27 |
2022-05-27 |
Genentech Inc |
Administración de dosis para tratamiento con anticuerpos antagonistas anti-tigit y anti-pd-l1
|
|
MX2022003523A
(es)
|
2019-09-27 |
2022-04-25 |
Glaxosmithkline Ip Dev Ltd |
Proteinas de union a antigenos.
|
|
CA3153785A1
(en)
|
2019-09-28 |
2021-04-01 |
AskGene Pharma, Inc. |
Cytokine prodrugs and dual-prodrugs
|
|
US20220354880A1
(en)
|
2019-09-30 |
2022-11-10 |
Astrazeneca Ab |
Combination treatment for cancer
|
|
KR20220075382A
(ko)
|
2019-09-30 |
2022-06-08 |
인사이트 코포레이션 |
면역조절제로서의 피리도[3,2-d]피리미딘 화합물
|
|
EP3800201A1
(en)
|
2019-10-01 |
2021-04-07 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Cd28h stimulation enhances nk cell killing activities
|
|
WO2021067374A1
(en)
|
2019-10-01 |
2021-04-08 |
Incyte Corporation |
Bicyclic heterocycles as fgfr inhibitors
|
|
WO2021067644A1
(en)
|
2019-10-01 |
2021-04-08 |
Silverback Therapeutics, Inc. |
Combination therapy with immune stimulatory conjugates
|
|
US20220354811A1
(en)
|
2019-10-03 |
2022-11-10 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for modulating macrophages polarization
|
|
CN115916233A
(zh)
|
2019-10-03 |
2023-04-04 |
Xencor股份有限公司 |
靶向IL-12异源二聚体Fc融合蛋白
|
|
KR20220075351A
(ko)
*
|
2019-10-04 |
2022-06-08 |
씨젠 인크. |
항-pd-l1 항체 및 항체-약물 접합체
|
|
EP4037710A1
(en)
|
2019-10-04 |
2022-08-10 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Methods and pharmaceutical composition for the treatment of ovarian cancer, breast cancer or pancreatic cancer
|
|
PE20221905A1
(es)
|
2019-10-11 |
2022-12-23 |
Incyte Corp |
Aminas biciclicas como inhibidoras de la cdk2
|
|
TW202128757A
(zh)
|
2019-10-11 |
2021-08-01 |
美商建南德克公司 |
具有改善之特性的 PD-1 標靶 IL-15/IL-15Rα FC 融合蛋白
|
|
WO2021076574A2
(en)
|
2019-10-14 |
2021-04-22 |
Aro Biotherapeutics Company |
Fn3 domain-sirna conjugates and uses thereof
|
|
KR20220100879A
(ko)
|
2019-10-14 |
2022-07-18 |
인사이트 코포레이션 |
Fgfr 저해제로서의 이환식 헤테로사이클
|
|
US12491255B2
(en)
|
2019-10-14 |
2025-12-09 |
Aro Biotherapeutics Company |
EPCAM binding fibronectin type III domains
|
|
CN114786682B
(zh)
|
2019-10-14 |
2024-07-16 |
Aro生物疗法公司 |
结合cd71的纤维粘连蛋白iii型结构域
|
|
US11566028B2
(en)
|
2019-10-16 |
2023-01-31 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
WO2021074683A1
(en)
|
2019-10-16 |
2021-04-22 |
Avacta Life Sciences Limited |
Bispecific anti-pd-l1 and anti-fcrn polypeptides
|
|
EP4045686A1
(en)
|
2019-10-17 |
2022-08-24 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Methods for diagnosing nasal intestinal type adenocarcinomas
|
|
AU2020370832A1
(en)
|
2019-10-21 |
2022-05-19 |
Novartis Ag |
TIM-3 inhibitors and uses thereof
|
|
KR20220103947A
(ko)
|
2019-10-21 |
2022-07-25 |
노파르티스 아게 |
베네토클락스 및 tim-3 억제제를 사용한 조합 요법
|
|
US20220378817A1
(en)
|
2019-10-23 |
2022-12-01 |
Checkmate Pharmaceuticals, Inc. |
Synthetic rig-i-like receptor agonists
|
|
WO2021080682A1
(en)
|
2019-10-24 |
2021-04-29 |
Massachusetts Institute Of Technology |
Monoclonal antibodies that bind human cd161 and uses thereof
|
|
CA3155727A1
(en)
|
2019-10-25 |
2021-04-29 |
Cecile Chartier-Courtaud |
Gene editing of tumor infiltrating lymphocytes and uses of same in immunotherapy
|
|
PH12022551030A1
(en)
|
2019-10-28 |
2023-04-24 |
Shanghai Inst Materia Medica Cas |
Five-membered heterocyclic oxocarboxylic acid compound and medical use thereof
|
|
US20220409724A1
(en)
|
2019-10-29 |
2022-12-29 |
Eisai R&D Management Co., Ltd. |
Combination of a pd-1 antagonist, a vegfr/fgfr/ret tyrosine kinase inhibitor and a cbp/beta-catenin inhibitor for treating cancer
|
|
EP4051286A1
(en)
|
2019-10-29 |
2022-09-07 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Methods and compositions for treating uveal melanoma
|
|
WO2021091885A2
(en)
|
2019-11-04 |
2021-05-14 |
Alector Llc |
Siglec-9 ecd fusion molecules and methods of use thereof
|
|
EP4054591A1
(en)
|
2019-11-04 |
2022-09-14 |
Astrazeneca AB |
Combination therapy for treating cancer
|
|
US12090147B2
(en)
|
2019-11-05 |
2024-09-17 |
Celgene Corporation |
Combination therapy with 2-(4-chlorophenyl)-N-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)methyl)-2,2-difluoroacetamide
|
|
WO2021092220A1
(en)
|
2019-11-06 |
2021-05-14 |
Bristol-Myers Squibb Company |
Methods of identifying a subject with a tumor suitable for a checkpoint inhibitor therapy
|
|
CA3155922A1
(en)
|
2019-11-06 |
2021-05-14 |
Huang Huang |
Diagnostic and therapeutic methods for treatment of hematologic cancers
|
|
WO2021092221A1
(en)
|
2019-11-06 |
2021-05-14 |
Bristol-Myers Squibb Company |
Methods of identifying a subject with a tumor suitable for a checkpoint inhibitor therapy
|
|
JP2023500054A
(ja)
|
2019-11-07 |
2023-01-04 |
オンクセルナ セラピューティクス,インコーポレイテッド |
腫瘍微小環境の分類
|
|
US20220411499A1
(en)
|
2019-11-08 |
2022-12-29 |
Bristol-Myers Squibb Company |
LAG-3 Antagonist Therapy for Melanoma
|
|
KR20220101664A
(ko)
|
2019-11-11 |
2022-07-19 |
인사이트 코포레이션 |
Pd-1/pd-l1 억제제의 염 및 결정질 형태
|
|
US20220396839A1
(en)
|
2019-11-12 |
2022-12-15 |
Foundation Medicine, Inc. |
Methods of detecting a fusion gene encoding a neoantigen
|
|
MX2022005775A
(es)
|
2019-11-13 |
2022-06-09 |
Genentech Inc |
Compuestos terapeuticos y metodos de uso.
|
|
EP4058465A1
(en)
|
2019-11-14 |
2022-09-21 |
Cohbar Inc. |
Cxcr4 antagonist peptides
|
|
TWI836159B
(zh)
|
2019-11-19 |
2024-03-21 |
美商必治妥美雅史谷比公司 |
可作為helios蛋白質抑制劑之化合物
|
|
KR20220104208A
(ko)
|
2019-11-22 |
2022-07-26 |
세라밴스 바이오파마 알앤디 아이피, 엘엘씨 |
Alk5 억제제로서 치환된 1,5-나프티리딘 또는 퀴놀린
|
|
US20230000864A1
(en)
|
2019-11-22 |
2023-01-05 |
Sumitomo Pharma Oncology, Inc. |
Solid dose pharmaceutical composition
|
|
US11591339B2
(en)
|
2019-11-26 |
2023-02-28 |
Ikena Oncology, Inc. |
Solid forms of (R)-N-(2-(5-fluoropyridin-3-yl)-8-isopropylpyrazolo[ 1,5-a][1,3,5]triazin-4-yl)-2,3,4,9-tetrahydro-1H-carbazol-3-amine maleate as aryl hydrocarbon receptor (AHR) inhibitors
|
|
US20210154281A1
(en)
|
2019-11-26 |
2021-05-27 |
Massachusetts Institute Of Technology |
Cell-based cancer vaccines and cancer therapies
|
|
IL292924A
(en)
|
2019-11-26 |
2022-07-01 |
Novartis Ag |
Chimeric antigen receptors cd19 and cd22 and their uses
|
|
MX2022006134A
(es)
|
2019-11-26 |
2022-06-17 |
Bristol Myers Squibb Co |
Sales/cocristales de (r)-n-(4-clorofenil)-2-((1s,4s)-4-(6-fluoroqu inolin-4-il)ciclohexil)propanamida.
|
|
GB201917254D0
(en)
|
2019-11-27 |
2020-01-08 |
Adc Therapeutics Sa |
Combination therapy
|
|
EP3831849A1
(en)
|
2019-12-02 |
2021-06-09 |
LamKap Bio beta AG |
Bispecific antibodies against ceacam5 and cd47
|
|
KR20220131900A
(ko)
|
2019-12-04 |
2022-09-29 |
인사이트 코포레이션 |
Fgfr 억제제의 유도체
|
|
WO2021113479A1
(en)
|
2019-12-04 |
2021-06-10 |
Incyte Corporation |
Tricyclic heterocycles as fgfr inhibitors
|
|
US11897950B2
(en)
|
2019-12-06 |
2024-02-13 |
Augusta University Research Institute, Inc. |
Osteopontin monoclonal antibodies
|
|
WO2021113679A1
(en)
|
2019-12-06 |
2021-06-10 |
Mersana Therapeutics, Inc. |
Dimeric compounds as sting agonists
|
|
CA3161104A1
(en)
|
2019-12-11 |
2021-06-17 |
Cecile Chartier-Courtaud |
Processes for the production of tumor infiltrating lymphocytes (tils) and methods of using the same
|
|
KR20220114063A
(ko)
|
2019-12-13 |
2022-08-17 |
큐진 인크. |
신규한 인터루킨-15 (il-15) 융합 단백질 및 이의 용도
|
|
JP2023509366A
(ja)
|
2019-12-17 |
2023-03-08 |
カイメラ セラピューティクス, インコーポレイテッド |
Irak分解剤およびそれらの使用
|
|
EP4076434A1
(en)
|
2019-12-17 |
2022-10-26 |
Flagship Pioneering Innovations V, Inc. |
Combination anti-cancer therapies with inducers of iron-dependent cellular disassembly
|
|
US20220396577A1
(en)
|
2019-12-17 |
2022-12-15 |
Merck Sharp & Dohme Llc |
Novel substituted 1,3-8-triazaspiro[4,5] decane-2,4-dione compounds as indoleamine 2,3-dioxygenase (ido) and/or tryptophan 2,3-dioxygenase (tdo) inhibitors
|
|
WO2021127283A2
(en)
|
2019-12-17 |
2021-06-24 |
Kymera Therapeutics, Inc. |
Irak degraders and uses thereof
|
|
WO2021119753A1
(en)
|
2019-12-18 |
2021-06-24 |
Ctxt Pty Limited |
Compounds
|
|
EP4076508A1
(en)
|
2019-12-19 |
2022-10-26 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and vaccine compositions to treat cancers
|
|
KR20220118481A
(ko)
|
2019-12-19 |
2022-08-25 |
브리스톨-마이어스 스큅 컴퍼니 |
Dgk 억제제 및 체크포인트 길항제의 조합물
|
|
US20230057071A1
(en)
|
2019-12-20 |
2023-02-23 |
Novartis Ag |
Combination of anti tim-3 antibody mbg453 and anti tgf-beta antibody nis793, with or without decitabine or the anti pd-1 antibody spartalizumab, for treating myelofibrosis and myelodysplastic syndrome
|
|
CA3163003A1
(en)
|
2019-12-23 |
2021-07-01 |
Upender Velaparthi |
Substituted heteroaryl compounds useful as t cell activators
|
|
PH12022551522A1
(en)
|
2019-12-23 |
2024-01-29 |
Kymera Therapeutics Inc |
Smarca degraders and uses thereof
|
|
EP4081513B1
(en)
|
2019-12-23 |
2024-11-20 |
Bristol-Myers Squibb Company |
Substituted quinolinonyl piperazine compounds useful as t cell activators
|
|
AR120823A1
(es)
|
2019-12-23 |
2022-03-23 |
Bristol Myers Squibb Co |
Compuestos bicíclicos sustituidos útiles como activadores de células t
|
|
AU2020412698A1
(en)
|
2019-12-23 |
2022-08-18 |
Bristol-Myers Squibb Company |
Substituted piperazine derivatives useful as T cell activators
|
|
CN114846007B
(zh)
|
2019-12-23 |
2024-11-22 |
百时美施贵宝公司 |
可用作t细胞激活剂的经取代的喹唑啉基化合物
|
|
CN113045655A
(zh)
|
2019-12-27 |
2021-06-29 |
高诚生物医药(香港)有限公司 |
抗ox40抗体及其用途
|
|
JP7657230B2
(ja)
|
2020-01-03 |
2025-04-04 |
インサイト・コーポレイション |
A2a/a2b及びpd-1/pd-l1阻害剤を含む併用療法
|
|
WO2021138407A2
(en)
|
2020-01-03 |
2021-07-08 |
Marengo Therapeutics, Inc. |
Multifunctional molecules that bind to cd33 and uses thereof
|
|
CN116234829A
(zh)
|
2020-01-03 |
2023-06-06 |
马伦戈治疗公司 |
抗tcr抗体分子及其用途
|
|
CN115996950A
(zh)
|
2020-01-06 |
2023-04-21 |
高诚生物医药(香港)有限公司 |
抗tnfr2抗体和其用途
|
|
KR20220122752A
(ko)
|
2020-01-06 |
2022-09-02 |
브리스톨-마이어스 스큅 컴퍼니 |
면역조정제
|
|
MX2022008421A
(es)
|
2020-01-07 |
2022-09-23 |
Hifibio Hk Ltd |
Anticuerpo anti-galectina-9 y usos del mismo.
|
|
US20230140132A1
(en)
|
2020-01-07 |
2023-05-04 |
Merck Sharp & Dohme Llc |
Arginase inhibitors and methods of use
|
|
WO2021142203A1
(en)
|
2020-01-10 |
2021-07-15 |
Innate Tumor Immunity, Inc. |
Nlrp3 modulators
|
|
KR102653906B1
(ko)
|
2020-01-14 |
2024-04-03 |
신테카인, 인크. |
편향된 il2 뮤테인 방법 및 조성물
|
|
EP4090663A1
(en)
|
2020-01-15 |
2022-11-23 |
Blueprint Medicines Corporation |
Map4k1 inhibitors
|
|
US12012409B2
(en)
|
2020-01-15 |
2024-06-18 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
AU2021207348A1
(en)
|
2020-01-17 |
2022-08-11 |
Novartis Ag |
Combination comprising a TIM-3 inhibitor and a hypomethylating agent for use in treating myelodysplastic syndrome or chronic myelomonocytic leukemia
|
|
US20230076415A1
(en)
|
2020-01-17 |
2023-03-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma
|
|
WO2021194481A1
(en)
|
2020-03-24 |
2021-09-30 |
Genentech, Inc. |
Dosing for treatment with anti-tigit and anti-pd-l1 antagonist antibodies
|
|
WO2022050954A1
(en)
|
2020-09-04 |
2022-03-10 |
Genentech, Inc. |
Dosing for treatment with anti-tigit and anti-pd-l1 antagonist antibodies
|
|
CN115038466A
(zh)
|
2020-01-28 |
2022-09-09 |
葛兰素史密斯克莱知识产权发展有限公司 |
联合治疗及其用途和方法
|
|
CN115397456A
(zh)
|
2020-01-28 |
2022-11-25 |
基因泰克公司 |
用于治疗癌症的IL15/IL15Rα异二聚体Fc融合蛋白
|
|
JP2023512276A
(ja)
|
2020-01-30 |
2023-03-24 |
オーエヌエー セラピューティクス エセ.エレ. |
癌及び癌転移の治療のための併用療法
|
|
WO2021152400A1
(en)
|
2020-01-30 |
2021-08-05 |
Gnubiotics Sciences Sa |
Compositions comprising pig stomach mucins and uses thereof
|
|
MX2022009391A
(es)
|
2020-01-31 |
2022-09-26 |
Genentech Inc |
Metodos para inducir linfocitos t especificos para neoepitopo con un antagonista de union al eje de pd-1 y una vacuna de arn.
|
|
WO2021156360A1
(en)
|
2020-02-05 |
2021-08-12 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for discontinuing a treatment with a tyrosine kinase inhibitor (tki)
|
|
KR20220139915A
(ko)
|
2020-02-06 |
2022-10-17 |
브리스톨-마이어스 스큅 컴퍼니 |
Il-10 및 그의 용도
|
|
CA3170133A1
(en)
|
2020-02-07 |
2021-08-12 |
AI Therapeutics, Inc. |
Anti-viral compositions and methods of use
|
|
WO2021167964A1
(en)
|
2020-02-18 |
2021-08-26 |
Alector Llc |
Pilra antibodies and methods of use thereof
|
|
JP7735291B2
(ja)
|
2020-02-21 |
2025-09-08 |
エーアールエス ファーマシューティカルズ、インコーポレイテッド |
ネクチン-4抗体コンジュゲートおよびその使用
|
|
AU2021226582A1
(en)
|
2020-02-26 |
2022-10-13 |
Biograph 55, Inc. |
C19 C38 bispecific antibodies
|
|
WO2021174045A1
(en)
|
2020-02-28 |
2021-09-02 |
Bristol-Myers Squibb Company |
Radiolabeled fibronectin based scaffolds and antibodies and theranostic uses thereof
|
|
EP4110955A1
(en)
|
2020-02-28 |
2023-01-04 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for diagnosing, prognosing and managing treatment of breast cancer
|
|
WO2021171264A1
(en)
|
2020-02-28 |
2021-09-02 |
Novartis Ag |
Dosing of a bispecific antibody that binds cd123 and cd3
|
|
EP4114529A1
(en)
|
2020-03-03 |
2023-01-11 |
PIC Therapeutics, Inc. |
Eif4e inhibitors and uses thereof
|
|
CN115484978A
(zh)
|
2020-03-05 |
2022-12-16 |
尼奥克斯医疗有限公司 |
使用免疫细胞治疗癌症的方法和组合物
|
|
EP4114450A1
(en)
|
2020-03-06 |
2023-01-11 |
Stichting Het Nederlands Kanker Instituut- Antoni van Leeuwenhoek Ziekenhuis |
Modulating anti-tumor immunity
|
|
WO2021178779A1
(en)
|
2020-03-06 |
2021-09-10 |
Incyte Corporation |
Combination therapy comprising axl/mer and pd-1/pd-l1 inhibitors
|
|
WO2021177980A1
(en)
|
2020-03-06 |
2021-09-10 |
Genentech, Inc. |
Combination therapy for cancer comprising pd-1 axis binding antagonist and il6 antagonist
|
|
EP4114398A1
(en)
|
2020-03-06 |
2023-01-11 |
Celgene Quanticel Research, Inc. |
Combination of an lsd-1 inhibitor and nivolumab for use in treating sclc or sqnsclc
|
|
AU2021232158A1
(en)
|
2020-03-06 |
2022-09-29 |
Ona Therapeutics, S.L. |
Anti-CD36 antibodies and their use to treat cancer
|
|
WO2021183318A2
(en)
|
2020-03-09 |
2021-09-16 |
President And Fellows Of Harvard College |
Methods and compositions relating to improved combination therapies
|
|
EP4118118A1
(en)
|
2020-03-09 |
2023-01-18 |
Bristol-Myers Squibb Company |
Antibodies to cd40 with enhanced agonist activity
|
|
PH12022552458A1
(en)
|
2020-03-19 |
2024-01-22 |
Kymera Therapeutics Inc |
Mdm2 degraders and uses thereof
|
|
CN115298165B
(zh)
|
2020-03-19 |
2024-09-17 |
艾库斯生物科学有限公司 |
作为HIF-2α抑制剂的四氢化萘和四氢喹啉化合物
|
|
CN115768792A
(zh)
|
2020-03-23 |
2023-03-07 |
百时美施贵宝公司 |
抗ccr8抗体用于治疗癌症
|
|
TW202140441A
(zh)
|
2020-03-23 |
2021-11-01 |
美商必治妥美雅史谷比公司 |
經取代之側氧基異吲哚啉化合物
|
|
CN115362166A
(zh)
|
2020-03-30 |
2022-11-18 |
百时美施贵宝公司 |
免疫调节剂
|
|
TW202204339A
(zh)
|
2020-03-31 |
2022-02-01 |
美商施萬生物製藥研發 Ip有限責任公司 |
經取代的嘧啶及使用方法
|
|
WO2021202959A1
(en)
|
2020-04-03 |
2021-10-07 |
Genentech, Inc. |
Therapeutic and diagnostic methods for cancer
|
|
JPWO2021206158A1
(enExample)
|
2020-04-10 |
2021-10-14 |
|
|
|
CN115916223A
(zh)
|
2020-04-10 |
2023-04-04 |
朱诺治疗学股份有限公司 |
与用靶向b细胞成熟抗原的嵌合抗原受体工程化的细胞疗法相关的方法和用途
|
|
US20230151024A1
(en)
|
2020-04-10 |
2023-05-18 |
Ono Pharmaceutical Co., Ltd. |
Sting agonistic compound
|
|
CN115461362A
(zh)
|
2020-04-14 |
2022-12-09 |
葛兰素史密斯克莱知识产权发展有限公司 |
基于ICOS抗体和PD-L1抗体TGF-β受体融合蛋白的癌症组合疗法
|
|
CR20220584A
(es)
|
2020-04-16 |
2023-02-15 |
Incyte Corp |
Inhibidores de kras tricíclicos fusionados
|
|
WO2021216572A1
(en)
|
2020-04-20 |
2021-10-28 |
Massachusetts Institute Of Technology |
Lipid compositions for delivery of sting agonist compounds and uses thereof
|
|
WO2021216488A1
(en)
|
2020-04-21 |
2021-10-28 |
Regeneron Pharmaceuticals, Inc. |
Il-2 variants with reduced binding to il-2 receptor alpha and uses thereof
|
|
MX2022013112A
(es)
|
2020-04-22 |
2023-01-16 |
Dragonfly Therapeutics Inc |
Fórmulacion, regimen de dosificación y proceso de manufactura de proteínas heterodiméricas fusionadas con fc.
|
|
JP2023524639A
(ja)
|
2020-04-22 |
2023-06-13 |
アイオバンス バイオセラピューティクス,インコーポレイテッド |
患者特異的免疫療法用細胞の製造調整システム及び調整方法
|
|
TW202206100A
(zh)
|
2020-04-27 |
2022-02-16 |
美商西健公司 |
癌症之治療
|
|
JP2023523450A
(ja)
|
2020-04-28 |
2023-06-05 |
ジェネンテック, インコーポレイテッド |
非小細胞肺がん免疫療法のための方法及び組成物
|
|
US20230181756A1
(en)
|
2020-04-30 |
2023-06-15 |
Novartis Ag |
Ccr7 antibody drug conjugates for treating cancer
|
|
JP2023524257A
(ja)
|
2020-05-05 |
2023-06-09 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
Pd-1軸阻害剤に対する応答の予測
|
|
CA3181538A1
(en)
|
2020-05-05 |
2021-11-11 |
Teon Therapeutics, Inc. |
Cannabinoid receptor type 2 (cb2) modulators and uses thereof
|
|
CR20220565A
(es)
|
2020-05-06 |
2023-01-13 |
Merck Sharp & Dohme Llc |
Inhibidores de il4i1 y métodos de uso
|
|
EP4146683A1
(en)
|
2020-05-08 |
2023-03-15 |
Alpine Immune Sciences, Inc. |
April and baff inhibitory immunomodulatory proteins and methods of use thereof
|
|
WO2021231526A1
(en)
|
2020-05-13 |
2021-11-18 |
Incyte Corporation |
Fused pyrimidine compounds as kras inhibitors
|
|
CN116323647A
(zh)
|
2020-05-13 |
2023-06-23 |
博纳姆治疗公司 |
蛋白质复合物的组合物及其使用方法
|
|
US12390537B2
(en)
|
2020-05-13 |
2025-08-19 |
Massachusetts Institute Of Technology |
Compositions of polymeric microdevices and methods of use thereof in cancer immunotherapy
|
|
WO2021231732A1
(en)
|
2020-05-15 |
2021-11-18 |
Bristol-Myers Squibb Company |
Antibodies to garp
|
|
AU2021280245A1
(en)
|
2020-05-26 |
2022-12-08 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating cervical cancer by administering a PD-1 inhibitor
|
|
US20230212231A1
(en)
|
2020-05-26 |
2023-07-06 |
Institut National De La Santé Et De La Recherche Médicale (Inserm) |
Severe acute respiratory syndrome coronavirus 2 (sars-cov-2) polypeptides and uses thereof for vaccine purposes
|
|
WO2021243207A1
(en)
|
2020-05-28 |
2021-12-02 |
Modernatx, Inc. |
Use of mrnas encoding ox40l, il-23 and il-36gamma for treating cancer
|
|
US20230173095A1
(en)
|
2020-05-29 |
2023-06-08 |
President And Fellows Of Harvard College |
Living cells engineered with polyphenol-functionalized biologically active nanocomplexes
|
|
CN115698068A
(zh)
|
2020-06-02 |
2023-02-03 |
艾库斯生物科学有限公司 |
抗tigit抗体
|
|
TW202210483A
(zh)
|
2020-06-03 |
2022-03-16 |
美商凱麥拉醫療公司 |
Irak降解劑之結晶型
|
|
US20230250110A1
(en)
|
2020-06-03 |
2023-08-10 |
Kymera Therapeutics, Inc. |
Deuterated irak degraders and uses thereof
|
|
US11767353B2
(en)
|
2020-06-05 |
2023-09-26 |
Theraly Fibrosis, Inc. |
Trail compositions with reduced immunogenicity
|
|
WO2021249969A1
(en)
|
2020-06-10 |
2021-12-16 |
Merck Patent Gmbh |
Combination product for the treatment of cancer diseases
|
|
WO2021253041A1
(en)
|
2020-06-10 |
2021-12-16 |
Theravance Biopharma R&D Ip, Llc |
Naphthyridine derivatives useful as alk5 inhibitors
|
|
CN115698719A
(zh)
|
2020-06-12 |
2023-02-03 |
基因泰克公司 |
用于癌症免疫疗法的方法和组合物
|
|
CN115916182A
(zh)
|
2020-06-16 |
2023-04-04 |
基因泰克公司 |
用于治疗三阴性乳腺癌的方法和组合物
|
|
WO2021257124A1
(en)
|
2020-06-18 |
2021-12-23 |
Genentech, Inc. |
Treatment with anti-tigit antibodies and pd-1 axis binding antagonists
|
|
AR122644A1
(es)
|
2020-06-19 |
2022-09-28 |
Onxeo |
Nuevas moléculas de ácido nucleico conjugado y sus usos
|
|
WO2021258010A1
(en)
|
2020-06-19 |
2021-12-23 |
Gossamer Bio Services, Inc. |
Oxime compounds useful as t cell activators
|
|
CN111925434B
(zh)
*
|
2020-06-22 |
2023-06-27 |
南昌大学 |
一种单克隆抗体的筛选方法
|
|
JP2023531676A
(ja)
|
2020-06-23 |
2023-07-25 |
ノバルティス アーゲー |
3-(1-オキソイソインドリン-2-イル)ピぺリジン-2,6-ジオン誘導体を含む投与レジメン
|
|
WO2021262969A1
(en)
|
2020-06-24 |
2021-12-30 |
The General Hospital Corporation |
Materials and methods of treating cancer
|
|
EP4171550A1
(en)
|
2020-06-25 |
2023-05-03 |
Celgene Corporation |
Methods for treating cancer with combination therapies
|
|
MX2022016548A
(es)
|
2020-06-26 |
2023-03-14 |
Amgen Inc |
Muteínas de il-10 y proteínas de fusión de las mismas.
|
|
US20230355804A1
(en)
|
2020-06-29 |
2023-11-09 |
Flagship Pioneering Innovations V, Inc. |
Viruses engineered to promote thanotransmission and their use in treating cancer
|
|
JP7741831B2
(ja)
|
2020-06-30 |
2025-09-18 |
アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル |
術前補助療法及び根治手術後の固形がんを患っている患者の再発及び/又は死亡のリスクを予測するための方法
|
|
EP4172621A1
(en)
|
2020-06-30 |
2023-05-03 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting the risk of recurrence and/or death of patients suffering from a solid cancer after preoperative adjuvant therapies
|
|
WO2022003554A1
(en)
|
2020-07-01 |
2022-01-06 |
Pfizer Inc. |
Biomarkers for pd-1 axis binding antagonist therapy
|
|
CA3183993A1
(en)
|
2020-07-01 |
2022-01-06 |
Peter R. Baum |
Anti-asgr1 antibody conjugates and uses thereof
|
|
MX2023000292A
(es)
|
2020-07-07 |
2023-02-09 |
Celgene Corp |
Composiciones farmaceuticas que comprenden (s)-4-(4-(4-(((2-(2,6-d ioxopiperidin-3-il)-1-oxoisoindolin-4-il)oxi)metil)bencil)piperaz in-1-il)-3-fluorobenzonitrilo y metodos de uso de las mismas.
|
|
KR20230035576A
(ko)
|
2020-07-07 |
2023-03-14 |
비온테크 에스이 |
Hpv 양성 암 치료용 rna
|
|
TW202216778A
(zh)
|
2020-07-15 |
2022-05-01 |
美商安進公司 |
Tigit及cd112r阻斷
|
|
US11787775B2
(en)
|
2020-07-24 |
2023-10-17 |
Genentech, Inc. |
Therapeutic compounds and methods of use
|
|
EP4189395A1
(en)
|
2020-07-28 |
2023-06-07 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Methods and compositions for preventing and treating a cancer
|
|
US11857535B2
(en)
|
2020-07-30 |
2024-01-02 |
Kymera Therapeutics, Inc. |
Methods of treating mutant lymphomas
|
|
TW202221031A
(zh)
|
2020-07-30 |
2022-06-01 |
英商阿法克塔生命科學有限公司 |
血清半衰期延長之pd-l1抑制多肽
|
|
CN116134027B
(zh)
|
2020-08-03 |
2025-01-24 |
诺华股份有限公司 |
杂芳基取代的3-(1-氧代异吲哚啉-2-基)哌啶-2,6-二酮衍生物及其用途
|
|
WO2022032005A2
(en)
|
2020-08-05 |
2022-02-10 |
Synthekine, Inc. |
Il10rb binding molecules and methods of use
|
|
EP4192880A4
(en)
|
2020-08-05 |
2025-04-30 |
Synthekine, Inc. |
IL10 receptor-binding molecules and methods of use
|
|
KR20230061394A
(ko)
|
2020-08-05 |
2023-05-08 |
신테카인, 인크. |
IL10Ra 결합 분자 및 사용 방법
|
|
EP4192877A4
(en)
|
2020-08-05 |
2024-10-16 |
Synthekine, Inc. |
SYNTHETIC IL2RB/IL2RG CYTOKINES
|
|
US12448457B2
(en)
|
2020-08-05 |
2025-10-21 |
Synthekine, Inc. |
GP130 binding molecules and methods of use
|
|
MX2023001707A
(es)
|
2020-08-10 |
2023-05-04 |
Shanghai Xunbaihui Biotechnology Co Ltd |
Composiciones y métodos para el tratamiento de enfermedades autoinmunes y cánceres por direccionamiento al miembro 8 de la superfamilia de inmunoglobulinas.
|
|
WO2022036146A1
(en)
|
2020-08-12 |
2022-02-17 |
Genentech, Inc. |
Diagnostic and therapeutic methods for cancer
|
|
KR20230074721A
(ko)
|
2020-08-17 |
2023-05-31 |
바이사이클티엑스 리미티드 |
Nectin-4에 특이적인 이환 콘쥬게이트 및 이의 용도
|
|
EP4199947A4
(en)
|
2020-08-18 |
2024-10-16 |
Onchilles Pharma, Inc. |
Modified porcine pancreatic elastase proteins
|
|
MX2023002123A
(es)
|
2020-08-26 |
2023-03-15 |
Regeneron Pharma |
Metodos de tratamiento de cancer mediante la administracion de un inhibidor de pd-1.
|
|
GB2616354A
(en)
|
2020-08-26 |
2023-09-06 |
Marengo Therapeutics Inc |
Methods of detecting TRBC1 or TRBC2
|
|
AU2021331476A1
(en)
|
2020-08-28 |
2023-05-04 |
Bristol-Myers Squibb Company |
Lag-3 antagonist therapy for hepatocellular carcinoma
|
|
US11999752B2
(en)
|
2020-08-28 |
2024-06-04 |
Incyte Corporation |
Vinyl imidazole compounds as inhibitors of KRAS
|
|
AU2021334361A1
(en)
|
2020-08-31 |
2023-05-11 |
Bristol-Myers Squibb Company |
Cell localization signature and immunotherapy
|
|
MX2023002570A
(es)
|
2020-09-02 |
2023-05-19 |
Pharmabcine Inc |
Terapia de combinacion de un antagonista de pd-1 y un antagonista para vegfr-2 para tratar a pacientes con cancer.
|
|
EP4208258A1
(en)
|
2020-09-03 |
2023-07-12 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating cancer pain by administering a pd-1 inhibitor
|
|
CN114316045B
(zh)
*
|
2020-09-29 |
2024-07-12 |
英诺欧奇生物医药(苏州)有限公司 |
抗pd-l1抗体及其用途
|
|
WO2022072601A1
(en)
*
|
2020-09-30 |
2022-04-07 |
Na Biotech Corp |
ANTI-ADENOSINE RECEPTOR (A2aR) ANTIBODIES
|
|
WO2022072783A1
(en)
|
2020-10-02 |
2022-04-07 |
Incyte Corporation |
Bicyclic dione compounds as inhibitors of kras
|
|
JP2023544410A
(ja)
|
2020-10-05 |
2023-10-23 |
ブリストル-マイヤーズ スクイブ カンパニー |
タンパク質を濃縮するための方法
|
|
US20230364127A1
(en)
|
2020-10-06 |
2023-11-16 |
Codiak Biosciences, Inc. |
Extracellular vesicle-aso constructs targeting stat6
|
|
TW202233671A
(zh)
|
2020-10-20 |
2022-09-01 |
美商建南德克公司 |
Peg結合抗mertk抗體及其使用方法
|
|
AU2021363536A1
(en)
|
2020-10-20 |
2023-02-23 |
F. Hoffmann-La Roche Ag |
Combination therapy of PD-1 axis binding antagonists and LRRK2 inhitibors
|
|
WO2022084531A1
(en)
|
2020-10-23 |
2022-04-28 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating glioma
|
|
JP2023548051A
(ja)
|
2020-10-23 |
2023-11-15 |
ブリストル-マイヤーズ スクイブ カンパニー |
肺がんのためのlag-3アンタゴニスト療法
|
|
WO2022093981A1
(en)
|
2020-10-28 |
2022-05-05 |
Genentech, Inc. |
Combination therapy comprising ptpn22 inhibitors and pd-l1 binding antagonists
|
|
MX2023004847A
(es)
|
2020-10-28 |
2023-07-11 |
Ikena Oncology Inc |
Combinación de un inhibidor del receptor de hidrocarburos de arilo (ahr) con un inhibidor de pdx o doxorrubicina.
|
|
KR20230095113A
(ko)
|
2020-11-04 |
2023-06-28 |
제넨테크, 인크. |
항-cd20/항-cd3 이중특이적 항체들과 항-cd79b 항체 약물 접합체들을 이용한 치료를 위한 투약
|
|
WO2022098638A2
(en)
|
2020-11-04 |
2022-05-12 |
Genentech, Inc. |
Dosing for treatment with anti-cd20/anti-cd3 bispecific antibodies
|
|
JP7716473B2
(ja)
|
2020-11-04 |
2025-07-31 |
ジェネンテック, インコーポレイテッド |
抗cd20/抗cd3二重特異性抗体の皮下投薬
|
|
IL302590A
(en)
|
2020-11-06 |
2023-07-01 |
Incyte Corp |
Process for preparing PD-1/PD-L1 inhibitor and salts and crystalline forms thereof
|
|
US11780836B2
(en)
|
2020-11-06 |
2023-10-10 |
Incyte Corporation |
Process of preparing a PD-1/PD-L1 inhibitor
|
|
CA3199095A1
(en)
|
2020-11-06 |
2022-05-12 |
Novartis Ag |
Cd19 binding molecules and uses thereof
|
|
WO2022099075A1
(en)
|
2020-11-06 |
2022-05-12 |
Incyte Corporation |
Crystalline form of a pd-1/pd-l1 inhibitor
|
|
EP4240415A1
(en)
|
2020-11-08 |
2023-09-13 |
Seagen Inc. |
Combination-therapy antibody drug conjugate with immune cell inhibitor
|
|
WO2022101302A1
(en)
|
2020-11-12 |
2022-05-19 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Antibodies conjugated or fused to the receptor-binding domain of the sars-cov-2 spike protein and uses thereof for vaccine purposes
|
|
EP4243827A1
(en)
|
2020-11-13 |
2023-09-20 |
Genentech, Inc. |
Methods and compositions comprising a krasg12c inhibitor and a pd-l1 binding antagonist for treating lung cancer
|
|
EP4245301A4
(en)
|
2020-11-13 |
2024-08-21 |
ONO Pharmaceutical Co., Ltd. |
TREATMENT OF CANCER BY COMBINED USE OF AN EP4 ANTAGONIST AND AN IMMUNE CHECKPOINT INHIBITOR
|
|
WO2022101463A1
(en)
|
2020-11-16 |
2022-05-19 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of the last c-terminal residues m31/41 of zikv m ectodomain for triggering apoptotic cell death
|
|
EP4244391A1
(en)
|
2020-11-16 |
2023-09-20 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for predicting and treating uveal melanoma
|
|
US20230416838A1
(en)
|
2020-11-16 |
2023-12-28 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for predicting and treating uveal melanoma
|
|
WO2022108931A2
(en)
|
2020-11-17 |
2022-05-27 |
Seagen Inc. |
Methods of treating cancer with a combination of tucatinib and an anti-pd-1/anti-pd-l1 antibody
|
|
KR20230131189A
(ko)
|
2020-12-02 |
2023-09-12 |
이케나 온콜로지, 인코포레이티드 |
Tead 억제제 및 이의 용도
|
|
WO2022120353A1
(en)
|
2020-12-02 |
2022-06-09 |
Ikena Oncology, Inc. |
Tead inhibitors and uses thereof
|
|
MX2023006488A
(es)
|
2020-12-02 |
2023-06-20 |
Genentech Inc |
Procedimientos y composiciones para el tratamiento neoadyuvante y adyuvante del carcinoma urotelial.
|
|
WO2022120179A1
(en)
|
2020-12-03 |
2022-06-09 |
Bristol-Myers Squibb Company |
Multi-tumor gene signatures and uses thereof
|
|
PH12023500013A1
(en)
|
2020-12-04 |
2024-03-11 |
Tidal Therapeutics Inc |
Ionizable cationic lipids and lipi nanoparticles, and methods of synthesis and use thereof
|
|
CA3204091A1
(en)
|
2020-12-08 |
2022-06-16 |
Infinity Pharmaceuticals, Inc. |
Eganelisib for use in the treatment of pd-l1 negative cancer
|
|
WO2022121846A1
(zh)
*
|
2020-12-08 |
2022-06-16 |
博际生物医药科技(杭州)有限公司 |
Pd-l1抗体及其应用
|
|
TW202237119A
(zh)
|
2020-12-10 |
2022-10-01 |
美商住友製藥腫瘤公司 |
Alk﹘5抑制劑和彼之用途
|
|
AU2021400725A1
(en)
|
2020-12-16 |
2023-08-03 |
Gossamer Bio Services, Inc. |
Compounds useful as t cell activators
|
|
US12180284B2
(en)
|
2020-12-16 |
2024-12-31 |
Molecular Templates, Inc. |
Clinical methods for use of a PD-L1-binding molecule comprising a Shiga toxin effector
|
|
HRP20240213T1
(hr)
|
2020-12-18 |
2024-04-26 |
Lamkap Bio Beta Ag |
Bispecifična antitijela protiv ceacam5 i cd47
|
|
WO2022135666A1
(en)
|
2020-12-21 |
2022-06-30 |
BioNTech SE |
Treatment schedule for cytokine proteins
|
|
TW202245808A
(zh)
|
2020-12-21 |
2022-12-01 |
德商拜恩迪克公司 |
用於治療癌症之治療性rna
|
|
WO2022135667A1
(en)
|
2020-12-21 |
2022-06-30 |
BioNTech SE |
Therapeutic rna for treating cancer
|
|
PL4267105T3
(pl)
|
2020-12-28 |
2025-06-30 |
Bristol-Myers Squibb Company |
Kompozycje przeciwciał i metody ich stosowania
|
|
WO2022146948A1
(en)
|
2020-12-28 |
2022-07-07 |
Bristol-Myers Squibb Company |
Subcutaneous administration of pd1/pd-l1 antibodies
|
|
CA3207066A1
(en)
|
2020-12-29 |
2022-07-07 |
Incyte Corporation |
Combination therapy comprising a2a/a2b inhibitors, pd-1/pd-l1 inhibitors, and anti-cd73 antibodies
|
|
MX2023007852A
(es)
|
2020-12-30 |
2023-07-07 |
Kymera Therapeutics Inc |
Degradadores de cinasas asociadas al receptor de interleucina-1 (irak) y usos de los mismos.
|
|
WO2022147532A1
(en)
|
2021-01-04 |
2022-07-07 |
Mersana Therapeutics, Inc. |
B7h4-targeted antibody-drug conjugates and methods of use thereof
|
|
CA3204162A1
(en)
|
2021-01-11 |
2022-07-14 |
Robert Kastelein |
Compositions and methods related to receptor pairing
|
|
US20250186539A2
(en)
|
2021-01-11 |
2025-06-12 |
Bicycletx Limited |
Methods for treating cancer
|
|
EP4277707A1
(en)
|
2021-01-14 |
2023-11-22 |
Askgene Pharma, Inc. |
Interferon prodrugs and methods of making and using the same
|
|
CN116963773A
(zh)
|
2021-01-21 |
2023-10-27 |
浙江养生堂天然药物研究所有限公司 |
治疗肿瘤的组合物及方法
|
|
JP2024505049A
(ja)
|
2021-01-29 |
2024-02-02 |
ノバルティス アーゲー |
抗cd73及び抗entpd2抗体のための投与方式並びにその使用
|
|
US20240423972A1
(en)
|
2021-02-01 |
2024-12-26 |
Yale University |
Chemotherapeutic bioadhesive particles with immunostimulatory molecules for cancer treatment
|
|
MX2023009059A
(es)
|
2021-02-02 |
2023-09-15 |
Liminal Biosciences Ltd |
Antagonistas de gpr84 y usos de estos.
|
|
KR20230153387A
(ko)
|
2021-02-02 |
2023-11-06 |
리미널 바이오사이언시스 리미티드 |
Gpr84 길항제 및 이의 용도
|
|
JP2024506844A
(ja)
|
2021-02-03 |
2024-02-15 |
ジェネンテック, インコーポレイテッド |
Cbl-b阻害剤としてのアミド
|
|
AR124800A1
(es)
|
2021-02-03 |
2023-05-03 |
Genentech Inc |
Lactamas como inhibidores cbl-b
|
|
WO2022171121A1
(zh)
|
2021-02-10 |
2022-08-18 |
同润生物医药(上海)有限公司 |
治疗肿瘤的方法和组合
|
|
BR112023016025A2
(pt)
*
|
2021-02-10 |
2023-10-31 |
Jiangxi Jemincare Group Co Ltd |
Anticorpo anti-pd-l1 e uso dos mesmos
|
|
CN117120090A
(zh)
|
2021-02-12 |
2023-11-24 |
林伯士萨顿公司 |
Hpk1拮抗剂和其用途
|
|
JP2024506339A
(ja)
|
2021-02-12 |
2024-02-13 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
がんの治療のための二環式テトラヒドロアゼピン誘導体
|
|
WO2022174268A1
(en)
|
2021-02-15 |
2022-08-18 |
Kymera Therapeutics, Inc. |
Irak4 degraders and uses thereof
|
|
IL304905A
(en)
|
2021-02-15 |
2023-10-01 |
Kymera Therapeutics Inc |
IRAK4 joints and their uses
|
|
GB202102396D0
(en)
|
2021-02-19 |
2021-04-07 |
Adc Therapeutics Sa |
Molecular adjuvant
|
|
PH12023552345A1
(en)
|
2021-03-02 |
2024-04-22 |
Glaxosmithkline Ip Dev Ltd |
Substituted pyridines as dnmt1 inhibitors
|
|
CN117295737A
(zh)
|
2021-03-05 |
2023-12-26 |
林伯士萨顿公司 |
Hpk1拮抗剂和其用途
|
|
US20240092942A1
(en)
|
2021-03-05 |
2024-03-21 |
Leadartis, S.L. |
Trimeric polypeptides and uses thereof in the treatment of cancer
|
|
JP2024510176A
(ja)
|
2021-03-08 |
2024-03-06 |
ブループリント メディシンズ コーポレイション |
Map4k1阻害剤
|
|
WO2022197641A1
(en)
|
2021-03-15 |
2022-09-22 |
Rapt Therapeutics, Inc. |
1h-pyrazolo[3,4-d]pyrimidin-6-yl-amine derivatives as hematopoietic progenitor kinase 1 (hpk1) modulators and/or inhibitors for the treatment of cancer and other diseases
|
|
CN115073599B
(zh)
*
|
2021-03-16 |
2023-04-28 |
北京天广实生物技术股份有限公司 |
结合pd-l1的抗体及其用途
|
|
WO2022194908A1
(en)
|
2021-03-17 |
2022-09-22 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma
|
|
CN117321418A
(zh)
|
2021-03-18 |
2023-12-29 |
诺华股份有限公司 |
癌症生物标志物及其使用方法
|
|
WO2022198101A1
(en)
|
2021-03-19 |
2022-09-22 |
Trained Therapeutix Discovery, Inc. |
Compounds for regulating trained immunity, and their methods of use
|
|
MX2023011007A
(es)
|
2021-03-23 |
2023-12-07 |
Regeneron Pharma |
Metodos para tratar el cancer en pacientes inmunosuprimidos o inmunocomprometidos mediante la administracion de un inhibidor de pd-1.
|
|
TW202304506A
(zh)
|
2021-03-25 |
2023-02-01 |
日商安斯泰來製藥公司 |
涉及抗claudin 18.2抗體的組合治療以治療癌症
|
|
WO2022204438A1
(en)
|
2021-03-25 |
2022-09-29 |
Oncxerna Therapeutics, Inc. |
Targeted therapies in cancer
|
|
CN117321087A
(zh)
|
2021-03-26 |
2023-12-29 |
先天制药公司 |
包含与细胞因子融合用于nk细胞衔接的nkp46结合位点、癌抗原结合位点的多特异性蛋白质
|
|
IL307262A
(en)
|
2021-03-29 |
2023-11-01 |
Juno Therapeutics Inc |
METHODS FOR DOSAGE AND THERAPY IN COMBINATION OF CHECKPOINT INHIBITOR AND CAR T CELL THERAPY
|
|
WO2022213062A1
(en)
|
2021-03-29 |
2022-10-06 |
Nimbus Saturn, Inc. |
Hpk1 antagonists and uses thereof
|
|
US20220325287A1
(en)
|
2021-03-31 |
2022-10-13 |
Flagship Pioneering Innovations V, Inc. |
Thanotransmission polypeptides and their use in treating cancer
|
|
JP2024511831A
(ja)
|
2021-03-31 |
2024-03-15 |
グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッド |
抗原結合タンパク質およびそれらの組み合わせ
|
|
US20240376224A1
(en)
|
2021-04-02 |
2024-11-14 |
The Regents Of The University Of California |
Antibodies against cleaved cdcp1 and uses thereof
|
|
CA3214240A1
(en)
|
2021-04-05 |
2022-10-13 |
Godwin Kwame KUMI |
Pyridinyl substituted oxoisoindoline compounds for the treatment of cancer
|
|
PT4320112T
(pt)
|
2021-04-06 |
2025-07-07 |
Bristol Myers Squibb Co |
Compostos de oxoisoindolina substituídos por piridinilo
|
|
TW202304979A
(zh)
|
2021-04-07 |
2023-02-01 |
瑞士商諾華公司 |
抗TGFβ抗體及其他治療劑用於治療增殖性疾病之用途
|
|
BR112023020832A2
(pt)
|
2021-04-08 |
2023-12-19 |
Marengo Therapeutics Inc |
Moléculas multifuncionais ligadas a tcr e seus usos
|
|
WO2022217123A2
(en)
|
2021-04-08 |
2022-10-13 |
Nurix Therapeutics, Inc. |
Combination therapies with cbl-b inhibitor compounds
|
|
EP4320156A1
(en)
|
2021-04-09 |
2024-02-14 |
Ose Immunotherapeutics |
Scaffold for bifunctioanl molecules comprising pd-1 or cd28 and sirp binding domains
|
|
CN117730097A
(zh)
|
2021-04-09 |
2024-03-19 |
思进公司 |
以抗tigit抗体治疗癌症的方法
|
|
JP2024513505A
(ja)
|
2021-04-09 |
2024-03-25 |
ビヨンドスプリング ファーマシューティカルズ,インコーポレイテッド |
腫瘍を治療するための組成物及び方法
|
|
JP2024515263A
(ja)
|
2021-04-09 |
2024-04-08 |
オーエスイー・イミュノセラピューティクス |
改善された特性を有する二機能性分子のための新規足場構造
|
|
JP2024513246A
(ja)
|
2021-04-09 |
2024-03-22 |
ジェネンテック, インコーポレイテッド |
Raf阻害剤及びpd-1軸阻害剤を用いた併用治療
|
|
KR20240007155A
(ko)
|
2021-04-09 |
2024-01-16 |
님버스 클리오, 인코포레이티드 |
Cbl-b 조절제 및 이의 용도
|
|
WO2022221170A1
(en)
|
2021-04-12 |
2022-10-20 |
Incyte Corporation |
Combination therapy comprising an fgfr inhibitor and a nectin-4 targeting agent
|
|
WO2022221227A1
(en)
|
2021-04-13 |
2022-10-20 |
Nuvalent, Inc. |
Amino-substituted heterocycles for treating cancers with egfr mutations
|
|
US12239710B2
(en)
|
2021-04-14 |
2025-03-04 |
Aro Biotherapeutics Company |
FN3 domain-siRNA conjugates and uses thereof
|
|
JP2024517610A
(ja)
|
2021-04-14 |
2024-04-23 |
アロ・バイオセラピューティクス・カンパニー |
Cd71に結合するフィブロネクチンiii型ドメイン
|
|
WO2022219080A1
(en)
|
2021-04-14 |
2022-10-20 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
New method to improve nk cells cytotoxicity
|
|
CN113150153B
(zh)
*
|
2021-04-15 |
2022-05-10 |
博奥信生物技术(南京)有限公司 |
一种抗人pdl1单克隆抗体及其用途
|
|
JP2024514879A
(ja)
|
2021-04-16 |
2024-04-03 |
イケナ オンコロジー, インコーポレイテッド |
Mek阻害剤及びその使用
|
|
JP2024517409A
(ja)
|
2021-04-16 |
2024-04-22 |
ノバルティス アーゲー |
抗体薬物結合体及びその作成方法
|
|
CA3212610A1
(en)
|
2021-04-20 |
2022-10-27 |
Philip MOQUIST |
Modulation of antibody-dependent cellular cytotoxicity
|
|
EP4326903A1
(en)
|
2021-04-23 |
2024-02-28 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Methods and compositions for treating cell senescence accumulation related disease
|
|
KR20240005691A
(ko)
|
2021-04-30 |
2024-01-12 |
에프. 호프만-라 로슈 아게 |
항-cd20/항-cd3 이중특이적 항체 및 항-cd79b 항체 약물 접합체를 이용한 병용 치료를 위한 투약
|
|
WO2022227015A1
(en)
|
2021-04-30 |
2022-11-03 |
Merck Sharp & Dohme Corp. |
Il4i1 inhibitors and methods of use
|
|
JP2024516230A
(ja)
|
2021-04-30 |
2024-04-12 |
ジェネンテック, インコーポレイテッド |
がんのための治療及び診断方法並びに組成物
|
|
AU2022271290A1
(en)
|
2021-05-07 |
2023-11-23 |
Kymera Therapeutics, Inc. |
Cdk2 degraders and uses thereof
|
|
CA3215856A1
(en)
|
2021-05-07 |
2022-11-10 |
Alison O'neill |
Anti-il-27 antibodies and uses thereof
|
|
TW202310871A
(zh)
|
2021-05-14 |
2023-03-16 |
美商建南德克公司 |
用莫蘇妥珠單抗及帕羅托珠單抗維多汀治療cd20陽性增生性失調之方法
|
|
AR125874A1
(es)
|
2021-05-18 |
2023-08-23 |
Novartis Ag |
Terapias de combinación
|
|
WO2022243378A1
(en)
|
2021-05-18 |
2022-11-24 |
Kymab Limited |
Uses of anti-icos antibodies
|
|
US20240226115A1
(en)
|
2021-05-21 |
2024-07-11 |
Arcus Biosciences, Inc. |
Axl inhibitor compounds
|
|
JP2024518641A
(ja)
|
2021-05-21 |
2024-05-01 |
天津立博美華基因科技有限責任公司 |
医薬物組合せ及びその使用
|
|
TW202313602A
(zh)
|
2021-05-21 |
2023-04-01 |
美商阿克思生物科學有限公司 |
Axl化合物
|
|
WO2022251853A1
(en)
|
2021-05-25 |
2022-12-01 |
Edelweiss Immune Inc |
C-x-c motif chemokine receptor 6 (cxcr6) binding molecules, and methods of using the same
|
|
WO2022251359A1
(en)
|
2021-05-26 |
2022-12-01 |
Theravance Biopharma R&D Ip, Llc |
Bicyclic inhibitors of alk5 and methods of use
|
|
AU2022280921A1
(en)
|
2021-05-26 |
2023-12-07 |
Centro De Inmunologia Molecular |
Use of therapeutic compositions for the treatment of patients with tumours of epithelial origin
|
|
WO2022254337A1
(en)
|
2021-06-01 |
2022-12-08 |
Novartis Ag |
Cd19 and cd22 chimeric antigen receptors and uses thereof
|
|
EP4346903A1
(en)
|
2021-06-03 |
2024-04-10 |
Synthorx, Inc. |
Head and neck cancer combination therapy comprising an il-2 conjugate and pembrolizumab
|
|
CN113234152B
(zh)
*
|
2021-06-03 |
2023-05-02 |
天津科技大学 |
程序性死亡受体-配体1(pd-l1)特异性结合多肽及应用
|
|
EP4347653A1
(en)
|
2021-06-04 |
2024-04-10 |
Boehringer Ingelheim International GmbH |
Anti-sirp-alpha antibodies
|
|
GB202107994D0
(en)
|
2021-06-04 |
2021-07-21 |
Kymab Ltd |
Treatment of cancer
|
|
AU2022288058A1
(en)
|
2021-06-07 |
2023-11-16 |
Agonox, Inc. |
Cxcr5, pd-1, and icos expressing tumor reactive cd4 t cells and their use
|
|
EP4352060A1
(en)
|
2021-06-09 |
2024-04-17 |
Incyte Corporation |
Tricyclic heterocycles as fgfr inhibitors
|
|
WO2022258678A1
(en)
|
2021-06-09 |
2022-12-15 |
Innate Pharma |
Multispecific proteins binding to nkp30, a cytokine receptor, a tumour antigen and cd16a
|
|
TW202313611A
(zh)
|
2021-06-09 |
2023-04-01 |
美商英塞特公司 |
作為fgfr抑制劑之三環雜環
|
|
MX2023014647A
(es)
|
2021-06-09 |
2024-01-31 |
Innate Pharma |
Proteinas de union a nkp46 multiespecificas.
|
|
WO2022258691A1
(en)
|
2021-06-09 |
2022-12-15 |
Innate Pharma |
Multispecific proteins binding to nkg2d, a cytokine receptor, a tumour antigen and cd16a
|
|
JP7556468B2
(ja)
|
2021-06-10 |
2024-09-26 |
小野薬品工業株式会社 |
Cd47阻害物質、免疫チェックポイント阻害物質および標準療法の併用によるがん治療法
|
|
US20230034659A1
(en)
*
|
2021-06-17 |
2023-02-02 |
Sparx Bioscience Limited |
Anti-pdl1 antibodies and uses thereof
|
|
US11981671B2
(en)
|
2021-06-21 |
2024-05-14 |
Incyte Corporation |
Bicyclic pyrazolyl amines as CDK2 inhibitors
|
|
WO2023278641A1
(en)
|
2021-06-29 |
2023-01-05 |
Flagship Pioneering Innovations V, Inc. |
Immune cells engineered to promote thanotransmission and uses thereof
|
|
KR20240028452A
(ko)
|
2021-07-02 |
2024-03-05 |
제넨테크, 인크. |
암을 치료하기 위한 방법 및 조성물
|
|
EP4367269A1
(en)
|
2021-07-05 |
2024-05-15 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Gene signatures for predicting survival time in patients suffering from renal cell carcinoma
|
|
AU2022306671A1
(en)
|
2021-07-07 |
2024-01-25 |
Incyte Corporation |
Tricyclic compounds as inhibitors of kras
|
|
IL309831A
(en)
|
2021-07-13 |
2024-02-01 |
BioNTech SE |
Multispecific binding agents against CD40 and CD137 in combined cancer therapy
|
|
JP2024529347A
(ja)
|
2021-07-14 |
2024-08-06 |
インサイト・コーポレイション |
Krasの阻害剤としての三環式化合物
|
|
JP2024529340A
(ja)
|
2021-07-14 |
2024-08-06 |
シンセカイン インコーポレイテッド |
新生物疾患の細胞療法に使用するための方法および組成物
|
|
EP4370523A1
(en)
|
2021-07-14 |
2024-05-22 |
Blueprint Medicines Corporation |
Heterocyclic compounds as map4k1 inhibitors
|
|
TW202321238A
(zh)
|
2021-07-15 |
2023-06-01 |
美商纜圖藥品公司 |
Map4k1抑制劑
|
|
US20230139492A1
(en)
|
2021-07-19 |
2023-05-04 |
Regeneron Pharmaceuticals, Inc. |
Combination of checkpoint inhibitors and an oncolytic virus for treating cancer
|
|
WO2023004431A2
(en)
*
|
2021-07-23 |
2023-01-26 |
The Trustees Of Columbia University In The City Of New York |
Characterization of potent and broadly neutralizing monoclonal antibodies against sars-cov-2, its variants, and related coronaviruses and methods of use
|
|
CN118871463A
(zh)
|
2021-07-28 |
2024-10-29 |
基因泰克公司 |
用于治疗癌症的方法和组合物
|
|
KR20240038008A
(ko)
|
2021-07-28 |
2024-03-22 |
에프. 호프만-라 로슈 아게 |
암 치료 방법 및 조성물
|
|
EP4377348A1
(en)
|
2021-07-30 |
2024-06-05 |
Seagen Inc. |
Treatment for cancer
|
|
CA3226281A1
(en)
|
2021-07-30 |
2023-02-02 |
ONA Therapeutics S.L. |
Anti-cd36 antibodies and their use to treat cancer
|
|
EP4380980A1
(en)
|
2021-08-03 |
2024-06-12 |
F. Hoffmann-La Roche AG |
Bispecific antibodies and methods of use
|
|
EP4380596A1
(en)
|
2021-08-04 |
2024-06-12 |
Genentech, Inc. |
Il15/il15r alpha heterodimeric fc-fusion proteins for the expansion of nk cells in the treatment of solid tumours
|
|
CN118284623A
(zh)
|
2021-08-23 |
2024-07-02 |
伊莫尼塔斯治疗公司 |
抗cd161抗体及其用途
|
|
JP2024534127A
(ja)
|
2021-08-25 |
2024-09-18 |
ピク セラピューティクス, インコーポレイテッド |
eIF4E阻害剤及びその使用
|
|
EP4392421A1
(en)
|
2021-08-25 |
2024-07-03 |
PIC Therapeutics, Inc. |
Eif4e inhibitors and uses thereof
|
|
CA3229855A1
(en)
|
2021-08-31 |
2023-03-09 |
Incyte Corporation |
Naphthyridine compounds as inhibitors of kras
|
|
WO2023034530A1
(en)
|
2021-09-02 |
2023-03-09 |
Teon Therapeutics, Inc. |
Methods of improving growth and function of immune cells
|
|
EP4396229A1
(en)
|
2021-09-02 |
2024-07-10 |
Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts |
Anti-cecam6 antibodies with reduced side-effects
|
|
CA3231180A1
(en)
|
2021-09-08 |
2023-03-16 |
Redona Therapeutics, Inc. |
Papd5 and/or papd7 inhibiting 4-oxo-1,4-dihydroquinoline-3-carboxylic acid derivatives
|
|
WO2023049697A1
(en)
|
2021-09-21 |
2023-03-30 |
Incyte Corporation |
Hetero-tricyclic compounds as inhibitors of kras
|
|
TW202321308A
(zh)
|
2021-09-30 |
2023-06-01 |
美商建南德克公司 |
使用抗tigit抗體、抗cd38抗體及pd—1軸結合拮抗劑治療血液癌症的方法
|
|
WO2023051926A1
(en)
|
2021-09-30 |
2023-04-06 |
BioNTech SE |
Treatment involving non-immunogenic rna for antigen vaccination and pd-1 axis binding antagonists
|
|
WO2023056421A1
(en)
|
2021-10-01 |
2023-04-06 |
Incyte Corporation |
Pyrazoloquinoline kras inhibitors
|
|
WO2023057882A1
(en)
|
2021-10-05 |
2023-04-13 |
Pfizer Inc. |
Combinations of azalactam compounds with a pd-1 axis binding antagonist for the treatment of cancer
|
|
TW202333802A
(zh)
|
2021-10-11 |
2023-09-01 |
德商拜恩迪克公司 |
用於肺癌之治療性rna(二)
|
|
CR20240197A
(es)
|
2021-10-14 |
2024-08-07 |
Incyte Corp |
Compuestos de quinolina como inhibidores de kras
|
|
CA3234552A1
(en)
|
2021-10-20 |
2023-04-27 |
Synthekine, Inc. |
Heterodimeric fc cytokines and uses thereof
|
|
JP2024539164A
(ja)
|
2021-10-21 |
2024-10-28 |
杭州阿諾生物医薬科技有限公司 |
融合ポリペプチドの一種とその使用
|
|
AU2022377637A1
(en)
|
2021-10-28 |
2024-05-02 |
Lyell Immunopharma, Inc. |
Methods for culturing immune cells
|
|
AU2022375806A1
(en)
|
2021-10-29 |
2023-12-14 |
Bristol-Myers Squibb Company |
Lag-3 antagonist therapy for hematological cancer
|
|
WO2023076556A1
(en)
|
2021-10-29 |
2023-05-04 |
Kymera Therapeutics, Inc. |
Irak4 degraders and synthesis thereof
|
|
CN116072211A
(zh)
*
|
2021-10-29 |
2023-05-05 |
京东方科技集团股份有限公司 |
抗体互补决定簇序列比对的方法及其装置和电子设备
|
|
US20240426823A1
(en)
|
2021-11-03 |
2024-12-26 |
Institut National de la Santé et de la Recherche Médicale |
Methods and compositions for treating triple negative breast cancer (tnbc)
|
|
WO2023081730A1
(en)
|
2021-11-03 |
2023-05-11 |
Teon Therapeutics, Inc. |
4-hydroxy-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide derivatives as cannabinoid cb2 receptor modulators for the treatment of cancer
|
|
WO2023079428A1
(en)
|
2021-11-03 |
2023-05-11 |
Pfizer Inc. |
Combination therapies using tlr7/8 agonist
|
|
WO2023080900A1
(en)
|
2021-11-05 |
2023-05-11 |
Genentech, Inc. |
Methods and compositions for classifying and treating kidney cancer
|
|
EP4429769A1
(en)
|
2021-11-09 |
2024-09-18 |
Sensei Biotherapeutics, Inc. |
Anti-vista antibodies and uses thereof
|
|
WO2023083439A1
(en)
|
2021-11-09 |
2023-05-19 |
BioNTech SE |
Tlr7 agonist and combinations for cancer treatment
|
|
EP4433504A1
(en)
|
2021-11-17 |
2024-09-25 |
Institut National de la Santé et de la Recherche Médicale |
Universal sarbecovirus vaccines
|
|
US20230226040A1
(en)
|
2021-11-22 |
2023-07-20 |
Incyte Corporation |
Combination therapy comprising an fgfr inhibitor and a kras inhibitor
|
|
EP4436969A2
(en)
|
2021-11-24 |
2024-10-02 |
Genentech, Inc. |
Bicyclic therapeutic compounds and methods of use in the treatment of cancer
|
|
US12110276B2
(en)
|
2021-11-24 |
2024-10-08 |
Genentech, Inc. |
Pyrazolo compounds and methods of use thereof
|
|
WO2023097211A1
(en)
|
2021-11-24 |
2023-06-01 |
The University Of Southern California |
Methods for enhancing immune checkpoint inhibitor therapy
|
|
WO2023102184A1
(en)
|
2021-12-03 |
2023-06-08 |
Incyte Corporation |
Bicyclic amine compounds as cdk12 inhibitors
|
|
US11976073B2
(en)
|
2021-12-10 |
2024-05-07 |
Incyte Corporation |
Bicyclic amines as CDK2 inhibitors
|
|
US12084453B2
(en)
|
2021-12-10 |
2024-09-10 |
Incyte Corporation |
Bicyclic amines as CDK12 inhibitors
|
|
WO2023111203A1
(en)
|
2021-12-16 |
2023-06-22 |
Onxeo |
New conjugated nucleic acid molecules and their uses
|
|
WO2023114984A1
(en)
|
2021-12-17 |
2023-06-22 |
Ikena Oncology, Inc. |
Tead inhibitors and uses thereof
|
|
WO2023122573A1
(en)
|
2021-12-20 |
2023-06-29 |
Synthorx, Inc. |
Head and neck cancer combination therapy comprising an il-2 conjugate and pembrolizumab
|
|
EP4452257A1
(en)
|
2021-12-21 |
2024-10-30 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma
|
|
WO2023122777A1
(en)
|
2021-12-22 |
2023-06-29 |
Gossamer Bio Services, Inc. |
Oxime derivatives useful as t cell activators
|
|
WO2023122778A1
(en)
|
2021-12-22 |
2023-06-29 |
Gossamer Bio Services, Inc. |
Pyridazinone derivatives useful as t cell activators
|
|
WO2023122772A1
(en)
|
2021-12-22 |
2023-06-29 |
Gossamer Bio Services, Inc. |
Oxime derivatives useful as t cell activators
|
|
AR128043A1
(es)
|
2021-12-22 |
2024-03-20 |
Incyte Corp |
Sales y formas sólidas de un inhibidor de fgfr y procesos para su preparación
|
|
WO2023129438A1
(en)
|
2021-12-28 |
2023-07-06 |
Wisconsin Alumni Research Foundation |
Hydrogel compositions for use for depletion of tumor associated macrophages
|
|
WO2023130081A1
(en)
|
2021-12-30 |
2023-07-06 |
Neoimmunetech, Inc. |
Method of treating a tumor with a combination of il-7 protein and vegf antagonist
|
|
WO2023137161A1
(en)
|
2022-01-14 |
2023-07-20 |
Amgen Inc. |
Triple blockade of tigit, cd112r, and pd-l1
|
|
MX2024008831A
(es)
|
2022-01-26 |
2024-07-25 |
Bristol Myers Squibb Co |
Terapia combinada para carcinoma hepatocelular.
|
|
EP4466291A4
(en)
|
2022-01-28 |
2025-07-16 |
Georgiamune Inc |
ANTIBODIES DIRECTED AGAINST PROGRAMMED CELL DEATH PROTEIN 1, PD-1 AGONISTS
|
|
WO2023142996A1
(zh)
|
2022-01-28 |
2023-08-03 |
上海岸阔医药科技有限公司 |
预防或治疗与抗肿瘤剂相关的疾病或病症的方法
|
|
IL314395A
(en)
|
2022-01-31 |
2024-09-01 |
Centessa Pharmaceuticals Uk Ltd |
Bispecific anti-CD47 and anti-PD-L1 activatable proteins and their uses
|
|
IL314437A
(en)
|
2022-01-31 |
2024-09-01 |
Kymera Therapeutics Inc |
IRAK joints and their uses
|
|
EP4472963A1
(en)
|
2022-02-01 |
2024-12-11 |
Arvinas Operations, Inc. |
Dgk targeting compounds and uses thereof
|
|
WO2023154799A1
(en)
|
2022-02-14 |
2023-08-17 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Combination immunotherapy for treating cancer
|
|
TWI864587B
(zh)
|
2022-02-14 |
2024-12-01 |
美商基利科學股份有限公司 |
抗病毒吡唑并吡啶酮化合物
|
|
US12074641B2
(en)
|
2022-02-15 |
2024-08-27 |
Bank Of America Corporation |
System and method for secured data transmission using LiFi and holochain network
|
|
US12052261B2
(en)
|
2022-02-15 |
2024-07-30 |
Bank Of America Corporation |
System and method for authenticating the receiving end of data transmission via LiFi and holochain network
|
|
WO2023159102A1
(en)
|
2022-02-17 |
2023-08-24 |
Regeneron Pharmaceuticals, Inc. |
Combinations of checkpoint inhibitors and oncolytic virus for treating cancer
|
|
JP2025505812A
(ja)
|
2022-02-21 |
2025-02-28 |
オンクオリティ ファーマシューティカルズ チャイナ リミテッド |
化合物及びその用途
|
|
US20230277669A1
(en)
|
2022-02-24 |
2023-09-07 |
Amazentis Sa |
Uses of urolithins
|
|
EP4482866A1
(en)
|
2022-02-25 |
2025-01-01 |
Bristol-Myers Squibb Company |
Combination therapy for colorectal carcinoma
|
|
JP7654346B2
(ja)
|
2022-03-03 |
2025-04-01 |
ファイザー・インク |
多重特異性抗体およびその使用
|
|
WO2023168404A1
(en)
|
2022-03-04 |
2023-09-07 |
Bristol-Myers Squibb Company |
Methods of treating a tumor
|
|
CA3253781A1
(en)
|
2022-03-07 |
2023-09-14 |
Incyte Corporation |
SOLIDS, SALTS AND PROCESSES FOR PREPARING A CDK2 INHIBITOR
|
|
EP4490191A1
(en)
|
2022-03-08 |
2025-01-15 |
Alentis Therapeutics AG |
Use of anti-claudin-1 antibodies to increase t cell availability
|
|
WO2023173053A1
(en)
|
2022-03-10 |
2023-09-14 |
Ikena Oncology, Inc. |
Mek inhibitors and uses thereof
|
|
WO2023173057A1
(en)
|
2022-03-10 |
2023-09-14 |
Ikena Oncology, Inc. |
Mek inhibitors and uses thereof
|
|
EP4493189A1
(en)
|
2022-03-14 |
2025-01-22 |
Laekna Limited |
Combination treatment for cancer
|
|
CN118871451A
(zh)
|
2022-03-18 |
2024-10-29 |
百时美施贵宝公司 |
分离多肽的方法
|
|
WO2023187130A1
(en)
|
2022-03-30 |
2023-10-05 |
LockBody Therapeutics Ltd |
Activatable bispecific anti-cd3 and anti-pd-l1 proteins and uses thereof
|
|
AU2022450448A1
(en)
|
2022-04-01 |
2024-10-10 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
|
WO2023192478A1
(en)
|
2022-04-01 |
2023-10-05 |
Bristol-Myers Squibb Company |
Combination therapy with anti-il-8 antibodies and anti-pd-1 antibodies for treating cancer
|
|
WO2023196987A1
(en)
|
2022-04-07 |
2023-10-12 |
Bristol-Myers Squibb Company |
Methods of treating tumor
|
|
WO2023196988A1
(en)
|
2022-04-07 |
2023-10-12 |
Modernatx, Inc. |
Methods of use of mrnas encoding il-12
|
|
CN119731651A
(zh)
|
2022-04-08 |
2025-03-28 |
百时美施贵宝公司 |
三级淋巴结构的机器学习标识、分类和量化
|
|
WO2023194656A1
(en)
|
2022-04-08 |
2023-10-12 |
Tilt Biotherapeutics Oy |
Monoclonal pd-l1 antibodies
|
|
AU2023253705A1
(en)
|
2022-04-13 |
2024-10-17 |
F. Hoffmann-La Roche Ag |
Pharmaceutical compositions of therapeutic proteins and methods of use
|
|
JP7579481B2
(ja)
|
2022-04-13 |
2024-11-07 |
ジェネンテック, インコーポレイテッド |
モスネツズマブの医薬組成物および使用方法
|
|
EP4507704A1
(en)
|
2022-04-15 |
2025-02-19 |
Iovance Biotherapeutics, Inc. |
Til expansion processes using specific cytokine combinations and/or akti treatment
|
|
WO2023211889A1
(en)
|
2022-04-25 |
2023-11-02 |
Ikena Oncology, Inc. |
Polymorphic compounds and uses thereof
|
|
WO2023214325A1
(en)
|
2022-05-05 |
2023-11-09 |
Novartis Ag |
Pyrazolopyrimidine derivatives and uses thereof as tet2 inhibitors
|
|
EP4522653A1
(en)
|
2022-05-11 |
2025-03-19 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
|
WO2023220703A1
(en)
|
2022-05-12 |
2023-11-16 |
Genentech, Inc. |
Methods and compositions comprising a shp2 inhibitor and a pd-l1 binding antagonist
|
|
US20250340641A1
(en)
|
2022-05-18 |
2025-11-06 |
Kymab Limited |
Uses of anti-icos antibodies
|
|
WO2023230554A1
(en)
|
2022-05-25 |
2023-11-30 |
Pfizer Inc. |
Combination of a braf inhibitor, an egfr inhibitor, and a pd-1 antagonist for the treatment of braf v600e-mutant, msi-h/dmmr colorectal cancer
|
|
WO2023230205A1
(en)
|
2022-05-25 |
2023-11-30 |
Ikena Oncology, Inc. |
Mek inhibitors and uses thereof
|
|
AR129423A1
(es)
|
2022-05-27 |
2024-08-21 |
Viiv Healthcare Co |
Compuestos útiles en la terapia contra el hiv
|
|
CN119562830A
(zh)
|
2022-06-02 |
2025-03-04 |
百时美施贵宝公司 |
抗体组合物及其使用方法
|
|
IL317449A
(en)
|
2022-06-07 |
2025-02-01 |
Genentech Inc |
Method for determining the efficacy of a lung cancer treatment comprising an anti-PD-L1 antagonist and an anti-TIGIT antibody-antagonist
|
|
JP2025519493A
(ja)
|
2022-06-08 |
2025-06-26 |
インサイト・コーポレイション |
Dgk阻害剤としての三環式トリアゾロ化合物
|
|
TW202423482A
(zh)
|
2022-06-08 |
2024-06-16 |
美商泰德治療公司 |
可電離陽離子脂質和脂質奈米顆粒、及其合成方法和用途
|
|
AU2023291779A1
(en)
|
2022-06-16 |
2024-10-17 |
Lamkap Bio Beta Ltd |
Combination therapy of bispecific antibodies against ceacam5 and cd47 and bispecific antibodies against ceacam5 and cd3
|
|
TW202413359A
(zh)
|
2022-06-22 |
2024-04-01 |
美商英塞特公司 |
雙環胺cdk12抑制劑
|
|
EP4543923A1
(en)
|
2022-06-22 |
2025-04-30 |
Juno Therapeutics, Inc. |
Treatment methods for second line therapy of cd19-targeted car t cells
|
|
US20240101557A1
(en)
|
2022-07-11 |
2024-03-28 |
Incyte Corporation |
Fused tricyclic compounds as inhibitors of kras g12v mutants
|
|
AU2023307937A1
(en)
|
2022-07-11 |
2025-01-30 |
Autonomous Therapeutics, Inc. |
Encrypted rna and methods of its use
|
|
AU2023306375A1
(en)
|
2022-07-12 |
2025-02-06 |
Hotspot Therapeutics, Inc. |
Cbl-b inhibitors and anti-pd1/anti-pd-l1 for use in the treatment of cancer
|
|
CA3261147A1
(en)
|
2022-07-13 |
2024-01-18 |
Genentech, Inc. |
DOSAGE FOR TREATMENT WITH BISOPECIFIC ANTI-FCRH5/ANTI-CD3 ANTIBODIES
|
|
EP4554943A1
(en)
|
2022-07-14 |
2025-05-21 |
Teon Therapeutics, Inc. |
Adenosine receptor antagonists and uses thereof
|
|
JP2025523845A
(ja)
|
2022-07-19 |
2025-07-25 |
ジェネンテック, インコーポレイテッド |
抗fcrh5/抗cd3二重特異性抗体による処置のための投薬
|
|
EP4561599A1
(en)
|
2022-07-27 |
2025-06-04 |
Astrazeneca AB |
Combinations of recombinant virus expressing interleukin-12 with pd-1/pd-l1 inhibitors
|
|
TW202416950A
(zh)
|
2022-08-02 |
2024-05-01 |
英商利米那生物科技有限公司 |
雜芳基甲醯胺及相關gpr84拮抗劑及其用途
|
|
JP2025527248A
(ja)
|
2022-08-02 |
2025-08-20 |
リミナル・バイオサイエンシーズ・リミテッド |
置換ピリドンgpr84アンタゴニスト及びその使用
|
|
IL318577A
(en)
|
2022-08-02 |
2025-03-01 |
Liminal Biosciences Ltd |
ARYL-TRIAZOLYL AND RELATED GPR84 ANTAGONISTS AND THEIR USES
|
|
KR20250047766A
(ko)
|
2022-08-05 |
2025-04-04 |
주노 쎄러퓨티크스 인코퍼레이티드 |
Gprc5d 및 bcma에 특이적인 키메라 항원 수용체
|
|
EP4568950A1
(en)
|
2022-08-08 |
2025-06-18 |
Bristol-Myers Squibb Company |
Substituted tetrazolyl compounds useful as t cell activators
|
|
EP4568963A1
(en)
|
2022-08-09 |
2025-06-18 |
Bristol-Myers Squibb Company |
Tertiary amine substituted bicyclic compounds useful as t cell activators
|
|
WO2024033399A1
(en)
|
2022-08-10 |
2024-02-15 |
Institut National de la Santé et de la Recherche Médicale |
Sigmar1 ligand for the treatment of pancreatic cancer
|
|
WO2024033400A1
(en)
|
2022-08-10 |
2024-02-15 |
Institut National de la Santé et de la Recherche Médicale |
Sk2 inhibitor for the treatment of pancreatic cancer
|
|
AR130167A1
(es)
|
2022-08-11 |
2024-11-13 |
Hoffmann La Roche |
Derivados bicíclicos de tetrahidroazepina
|
|
JP2025526727A
(ja)
|
2022-08-11 |
2025-08-15 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
二環式テトラヒドロチアゼピン誘導体
|
|
JP2025526683A
(ja)
|
2022-08-11 |
2025-08-15 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
二環式テトラヒドロチアゼピン誘導体
|
|
CA3262845A1
(en)
|
2022-08-11 |
2024-02-15 |
F. Hoffmann-La Roche Ag |
BICYCLIC TETRAHYDROTHIAZEPINE DERIVATIVES
|
|
WO2024040175A1
(en)
|
2022-08-18 |
2024-02-22 |
Pulmatrix Operating Company, Inc. |
Methods for treating cancer using inhaled angiogenesis inhibitor
|
|
WO2024040264A1
(en)
|
2022-08-19 |
2024-02-22 |
Massachusetts Institute Of Technology |
Compositions and methods for targeting dendritic cell lectins
|
|
IL318949A
(en)
|
2022-08-23 |
2025-04-01 |
Ono Pharmaceutical Co |
Bispecific antibody
|
|
EP4581052A1
(en)
|
2022-09-01 |
2025-07-09 |
University of Georgia Research Foundation, Inc. |
Compositions and methods for directing apolipoprotein l1 to induce mammalian cell death
|
|
JP2025531738A
(ja)
|
2022-09-01 |
2025-09-25 |
ジェネンテック, インコーポレイテッド |
膀胱がんの治療方法及び診断方法
|
|
EP4583860A1
(en)
|
2022-09-06 |
2025-07-16 |
Institut National de la Santé et de la Recherche Médicale |
Inhibitors of the ceramide metabolic pathway for overcoming immunotherapy resistance in cancer
|
|
WO2024056716A1
(en)
|
2022-09-14 |
2024-03-21 |
Institut National de la Santé et de la Recherche Médicale |
Methods and pharmaceutical compositions for the treatment of dilated cardiomyopathy
|
|
JP2025533015A
(ja)
|
2022-09-30 |
2025-10-03 |
アレンティス セラピューティクス アクチェンゲゼルシャフト |
薬物抵抗性肝細胞癌の処置
|
|
EP4599089A1
(en)
|
2022-10-05 |
2025-08-13 |
Genentech, Inc. |
Methods and compositions for classifying and treating bladder cancer
|
|
WO2024077191A1
(en)
|
2022-10-05 |
2024-04-11 |
Flagship Pioneering Innovations V, Inc. |
Nucleic acid molecules encoding trif and additionalpolypeptides and their use in treating cancer
|
|
WO2024077166A1
(en)
|
2022-10-05 |
2024-04-11 |
Genentech, Inc. |
Methods and compositions for classifying and treating lung cancer
|
|
EP4602078A2
(en)
|
2022-10-11 |
2025-08-20 |
Yale University |
Compositions and methods of using cell-penetrating antibodies
|
|
EP4606384A1
(en)
|
2022-10-19 |
2025-08-27 |
Astellas Pharma, Inc. |
Use of anti-cldn4-anti-cd137 bispecific antibody combined with pd-1 signal inhibitor for cancer treatment
|
|
WO2024084013A1
(en)
|
2022-10-20 |
2024-04-25 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Combination therapy for the treatment of cancer
|
|
WO2024086827A2
(en)
|
2022-10-20 |
2024-04-25 |
Repertoire Immune Medicines, Inc. |
Cd8 t cell targeted il2
|
|
WO2024086739A1
(en)
|
2022-10-20 |
2024-04-25 |
Synthekine, Inc. |
Methods and compositions of il12 muteins and il2 muteins
|
|
EP4605000A1
(en)
|
2022-10-21 |
2025-08-27 |
Institut National de la Santé et de la Recherche Médicale |
Methods and pharmaceutical compositions for the treatment of osteoarthritis
|
|
EP4608390A1
(en)
|
2022-10-24 |
2025-09-03 |
Cancer Research Technology Limited |
Tumour sensitisation to checkpoint inhibitors with redox status modifier
|
|
WO2024089417A1
(en)
|
2022-10-24 |
2024-05-02 |
Memorial Sloan-Kettering Cancer Center |
Tumour stratification for responsiveness to an immune checkpoint inhibitor
|
|
WO2024091991A1
(en)
|
2022-10-25 |
2024-05-02 |
Genentech, Inc. |
Therapeutic and diagnostic methods for multiple myeloma
|
|
WO2024102635A1
(en)
|
2022-11-07 |
2024-05-16 |
Alector Llc |
Uses of siglec-9 ecd fusion molecules in cancer treatment
|
|
KR20250089492A
(ko)
|
2022-11-07 |
2025-06-18 |
네오이뮨텍, 인코퍼레이티드 |
비메틸화된 mgmt 프로모터를 갖는 종양의 치료 방법
|
|
US20240217989A1
(en)
|
2022-11-18 |
2024-07-04 |
Incyte Corporation |
Heteroaryl Fluoroalkenes As DGK Inhibitors
|
|
CN120584182A
(zh)
|
2022-11-21 |
2025-09-02 |
艾欧凡斯生物治疗公司 |
肿瘤浸润淋巴细胞扩增的二维过程及其疗法
|
|
WO2024112894A1
(en)
|
2022-11-22 |
2024-05-30 |
PIC Therapeutics, Inc. |
Eif4e inhibitors and uses thereof
|
|
EP4622631A1
(en)
|
2022-11-23 |
2025-10-01 |
University of Georgia Research Foundation, Inc. |
Compositions and methods of use thereof for increasing immune responses
|
|
AU2023404228A1
(en)
|
2022-11-29 |
2025-06-19 |
Adlai Nortye Biopharma Co., Ltd. |
Fusion polypeptide and use thereof
|
|
WO2024118836A1
(en)
|
2022-11-30 |
2024-06-06 |
Iovance Biotherapeutics, Inc. |
Processes for production of tumor infiltrating lymphocytes with shortened rep step
|
|
JP2025541738A
(ja)
|
2022-12-01 |
2025-12-23 |
ビオンテック・ソシエタス・エウロパエア |
抗pd1abと化学療法での併用療法におけるcd40およびcd137に対する多重特異性抗体
|
|
JP2025539459A
(ja)
|
2022-12-01 |
2025-12-05 |
イナート・ファルマ・ソシエテ・アノニム |
癌におけるネオアジュバント処置のための組成物および方法
|
|
KR20250113508A
(ko)
|
2022-12-01 |
2025-07-25 |
메디뮨 리미티드 |
항-pd-l1 및 항-cd73 항체를 포함하는 암 치료를 위한 병용 요법
|
|
WO2024129778A2
(en)
|
2022-12-13 |
2024-06-20 |
Juno Therapeutics, Inc. |
Chimeric antigen receptors specific for baff-r and cd19 and methods and uses thereof
|
|
CN120418289A
(zh)
|
2022-12-14 |
2025-08-01 |
安斯泰来制药欧洲有限公司 |
结合cldn18.2和cd3的双特异性结合剂与免疫检查点抑制剂的联合疗法
|
|
WO2024137589A2
(en)
|
2022-12-20 |
2024-06-27 |
Genentech, Inc. |
Methods of treating pancreatic cancer with a pd-1 axis binding antagonist and an rna vaccine
|
|
AU2023409221A1
(en)
|
2022-12-21 |
2025-06-12 |
Bristol-Myers Squibb Company |
Combination therapy for lung cancer
|
|
WO2024137865A1
(en)
|
2022-12-22 |
2024-06-27 |
Gossamer Bio Services, Inc. |
Compounds useful as t cell activators
|
|
EP4646433A1
(en)
|
2023-01-06 |
2025-11-12 |
Lassen Therapeutics, Inc. |
Anti-il-18bp antibodies
|
|
EP4646432A1
(en)
|
2023-01-06 |
2025-11-12 |
Lassen Therapeutics, Inc. |
Anti-il-18bp antibodies
|
|
US20240269251A1
(en)
|
2023-01-09 |
2024-08-15 |
Flagship Pioneering Innovations V, Inc. |
Genetic switches and their use in treating cancer
|
|
WO2024150177A1
(en)
|
2023-01-11 |
2024-07-18 |
Advesya |
Treatment methods for solid tumors
|
|
TW202428575A
(zh)
|
2023-01-12 |
2024-07-16 |
美商英塞特公司 |
作為dgk抑制劑之雜芳基氟代烯烴
|
|
EP4649173A1
(en)
|
2023-01-13 |
2025-11-19 |
Akrivia Biomedics Limited |
Method of profiling diseases
|
|
WO2024151885A1
(en)
|
2023-01-13 |
2024-07-18 |
Iovance Biotherapeutics, Inc. |
Use of til as maintenance therapy for nsclc patients who achieved pr/cr after prior therapy
|
|
EP4658310A1
(en)
|
2023-01-30 |
2025-12-10 |
Kymab Limited |
Antibodies
|
|
EP4658687A1
(en)
|
2023-01-31 |
2025-12-10 |
University of Rochester |
Immune checkpoint blockade therapy for treating staphylococcus aureus infections
|
|
WO2024196952A1
(en)
|
2023-03-20 |
2024-09-26 |
Bristol-Myers Squibb Company |
Tumor subtype assessment for cancer therapy
|
|
WO2024197157A1
(en)
|
2023-03-21 |
2024-09-26 |
Biograph 55, Inc. |
Cd19/cd38 multispecific antibodies
|
|
WO2024200571A1
(en)
|
2023-03-28 |
2024-10-03 |
Institut National de la Santé et de la Recherche Médicale |
Method for discriminating mono-immunotherapy from combined immunotherapy in cancers
|
|
WO2024206357A1
(en)
|
2023-03-29 |
2024-10-03 |
Merck Sharp & Dohme Llc |
Il4i1 inhibitors and methods of use
|
|
WO2024208818A1
(en)
|
2023-04-04 |
2024-10-10 |
Innate Pharma |
Modular chimeric antigen receptor
|
|
WO2024216028A1
(en)
|
2023-04-12 |
2024-10-17 |
Agenus Inc. |
Methods of treating cancer using an anti-ctla4 antibody and an enpp1 inhibitor
|
|
WO2024213767A1
(en)
|
2023-04-14 |
2024-10-17 |
Institut National de la Santé et de la Recherche Médicale |
Engraftment of mesenchymal stromal cells engineered to stimulate immune infiltration in tumors
|
|
US20240390340A1
(en)
|
2023-04-18 |
2024-11-28 |
Incyte Corporation |
Pyrrolidine kras inhibitors
|
|
WO2024218512A1
(en)
|
2023-04-19 |
2024-10-24 |
Centessa Pharmaceuticals (Uk) Limited |
Activatable bispecific anti-cd89 and anti-pd-l1 proteins and uses thereof
|
|
WO2024224323A1
(en)
|
2023-04-24 |
2024-10-31 |
King Abdullah University Of Science Of Technology |
Compositions, systems and methods for multiplex detection of target biomarkers in a sample
|
|
WO2024223299A2
(en)
|
2023-04-26 |
2024-10-31 |
Isa Pharmaceuticals B.V. |
Methods of treating cancer by administering immunogenic compositions and a pd-1 inhibitor
|
|
WO2024228167A1
(en)
|
2023-05-03 |
2024-11-07 |
Iox Therapeutics Inc. |
Inkt cell modulator liposomal compositions and methods of use
|
|
TW202509069A
(zh)
|
2023-05-04 |
2025-03-01 |
美商諾瓦森塔股份有限公司 |
抗cd161抗體及其使用方法
|
|
TW202448949A
(zh)
|
2023-05-05 |
2024-12-16 |
美商建南德克公司 |
用抗fcrh5/抗cd3雙特異性抗體進行治療之給藥
|
|
TW202509014A
(zh)
|
2023-05-10 |
2025-03-01 |
美商纜圖藥品公司 |
GSK3α抑制劑及其使用方法
|
|
WO2024231384A1
(en)
|
2023-05-10 |
2024-11-14 |
Institut National de la Santé et de la Recherche Médicale |
Compositions for treating senescence related disease
|
|
AU2024268933A1
(en)
|
2023-05-10 |
2025-11-20 |
Chugai Seiyaku Kabushiki Kaisha |
Methods and compositions for treating cancer
|
|
WO2024245951A1
(en)
|
2023-05-26 |
2024-12-05 |
Institut National de la Santé et de la Recherche Médicale |
Combination of slc8a1 inhibitor and mitochondria-targeted antioxidant for treating melanoma
|
|
WO2024254227A1
(en)
|
2023-06-07 |
2024-12-12 |
Bristol-Myers Squibb Company |
Spirocyclic substituted oxoisoindolinyl piperidine-2,6-dione compound
|
|
WO2024254245A1
(en)
|
2023-06-09 |
2024-12-12 |
Incyte Corporation |
Bicyclic amines as cdk2 inhibitors
|
|
WO2024256635A1
(en)
|
2023-06-15 |
2024-12-19 |
Institut National de la Santé et de la Recherche Médicale |
Dpm1 inhibitor for treating cancer
|
|
WO2024261302A1
(en)
|
2023-06-22 |
2024-12-26 |
Institut National de la Santé et de la Recherche Médicale |
Nlrp3 inhibitors, pak1/2 inhibitors and/or caspase 1 inhibitors for use in the treatment of rac2 monogenic disorders
|
|
WO2024263853A1
(en)
|
2023-06-23 |
2024-12-26 |
Bristol-Myers Squibb Company |
Substituted oxoisoindolinyl piperidine-2,6-dione compound as anticancer agent
|
|
WO2024263195A1
(en)
|
2023-06-23 |
2024-12-26 |
Genentech, Inc. |
Methods for treatment of liver cancer
|
|
WO2024263904A1
(en)
|
2023-06-23 |
2024-12-26 |
Genentech, Inc. |
Methods for treatment of liver cancer
|
|
WO2024264017A2
(en)
|
2023-06-23 |
2024-12-26 |
Kymera Therapeutics, Inc. |
Irak degraders and uses thereof
|
|
WO2025003193A1
(en)
|
2023-06-26 |
2025-01-02 |
Institut National de la Santé et de la Recherche Médicale |
Sertraline and indatraline for disrupting intracellular cholesterol trafficking and subsequently inducing lysosomal damage and anti-tumor immunity
|
|
WO2025006811A1
(en)
|
2023-06-27 |
2025-01-02 |
Lyell Immunopharma, Inc. |
Methods for culturing immune cells
|
|
WO2025012417A1
(en)
|
2023-07-13 |
2025-01-16 |
Institut National de la Santé et de la Recherche Médicale |
Anti-neurotensin long fragment and anti-neuromedin n long fragment antibodies and uses thereof
|
|
WO2025024257A1
(en)
|
2023-07-21 |
2025-01-30 |
Genentech, Inc. |
Diagnostic and therapeutic methods for cancer
|
|
WO2025030002A2
(en)
|
2023-08-02 |
2025-02-06 |
Arvinas Operations, Inc. |
Dgk targeting compounds and uses thereof
|
|
WO2025038763A1
(en)
|
2023-08-15 |
2025-02-20 |
Bristol-Myers Squibb Company |
Ceramic hydroxyapatite chromatography flow through method
|
|
WO2025042742A1
(en)
|
2023-08-18 |
2025-02-27 |
Bristol-Myers Squibb Company |
Compositions comprising antibodies that bind bcma and cd3 and methods of treatment
|
|
TW202517247A
(zh)
|
2023-08-24 |
2025-05-01 |
美商英塞特公司 |
雙環dgk抑制劑
|
|
TW202515614A
(zh)
|
2023-08-25 |
2025-04-16 |
美商建南德克公司 |
治療非小細胞肺癌之方法及組成物
|
|
WO2025064197A1
(en)
|
2023-09-02 |
2025-03-27 |
Bristol-Myers Squibb Company |
Substituted azetidinyl oxoisoindolinyl piperidine-2,6-dione compounds
|
|
WO2025056180A1
(en)
|
2023-09-15 |
2025-03-20 |
BioNTech SE |
Methods of treatment using agents binding to epcam and cd137 in combination with pd-1 axis binding antagonists
|
|
WO2025073765A1
(en)
|
2023-10-03 |
2025-04-10 |
Institut National de la Santé et de la Recherche Médicale |
Methods of prognosis and treatment of patients suffering from melanoma
|
|
WO2025080593A1
(en)
|
2023-10-09 |
2025-04-17 |
Incyte Corporation |
Combination therapy using a kras g12d inhibitor and pd-1 inhibitor or pd-l1 inhibitor
|
|
WO2025080538A1
(en)
|
2023-10-09 |
2025-04-17 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating cancer with a combination of a pd1 inhibitor and a targeted immunocytokine
|
|
TW202515903A
(zh)
|
2023-10-12 |
2025-04-16 |
瑞士商百濟神州瑞士有限責任公司 |
手術前後基於抗pd-1之治療
|
|
WO2025078632A1
(en)
|
2023-10-12 |
2025-04-17 |
Institut National de la Santé et de la Recherche Médicale |
Methods of prognosis and treatment of patients suffering from cancer
|
|
WO2025085404A1
(en)
|
2023-10-16 |
2025-04-24 |
Genentech, Inc. |
Diagnostic and therapeutic methods for treating lung cancer
|
|
TW202532440A
(zh)
|
2023-10-19 |
2025-08-16 |
美商建南德克公司 |
用於治療HER2陽性癌症的IL15/IL15Rα異二聚體FC融合蛋白及HER2xCD3雙特異性抗體之組合
|
|
WO2025096487A1
(en)
|
2023-10-31 |
2025-05-08 |
Bristol-Myers Squibb Company |
Ubiquitin specific processing protease 1 (usp1) compounds
|
|
WO2025096505A1
(en)
|
2023-10-31 |
2025-05-08 |
Bristol-Myers Squibb Company |
Ubiquitin specific processing protease 1 (usp1) compounds
|
|
WO2025096494A1
(en)
|
2023-10-31 |
2025-05-08 |
Bristol-Myers Squibb Company |
Ubiquitin specific processing protease 1 (usp1) compounds
|
|
WO2025096490A1
(en)
|
2023-10-31 |
2025-05-08 |
Bristol-Myers Squibb Company |
Ubiquitin specific processing protease 1 (usp1) compounds
|
|
WO2025096539A1
(en)
|
2023-10-31 |
2025-05-08 |
Bristol-Myers Squibb Company |
Ubiquitin specific processing protease 1 (usp1) compounds
|
|
WO2025096489A1
(en)
|
2023-10-31 |
2025-05-08 |
Bristol-Myers Squibb Company |
Ubiquitin specific processing protease 1 (usp1) compounds
|
|
WO2025096488A1
(en)
|
2023-10-31 |
2025-05-08 |
Bristol-Myers Squibb Company |
Ubiquitin specific processing protease 1 (usp1) compounds
|
|
US20250163079A1
(en)
|
2023-11-01 |
2025-05-22 |
Incyte Corporation |
Kras inhibitors
|
|
WO2025096843A1
(en)
|
2023-11-03 |
2025-05-08 |
Amgen Inc. |
Bispecific molecules
|
|
WO2025106278A1
(en)
|
2023-11-17 |
2025-05-22 |
Mersana Therapeutics, Inc. |
Treatment of cancer using b7-h4-targeted antibody-drug conjugates
|
|
US20250179083A1
(en)
|
2023-12-05 |
2025-06-05 |
Incyte Corporation |
Tricyclic triazolo compounds as dgk inhibitors
|
|
WO2025122695A1
(en)
|
2023-12-06 |
2025-06-12 |
Incyte Corporation |
Combination therapy comprising dgk inhibitors and pd-1/pd-l1 inhibitors
|
|
WO2025120866A1
(en)
|
2023-12-08 |
2025-06-12 |
Astellas Pharma Inc. |
Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and agents stabilizing or increasing expression of cldn18.2
|
|
WO2025121445A1
(en)
|
2023-12-08 |
2025-06-12 |
Astellas Pharma Inc. |
Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and agents stabilizing or increasing expression of cldn18.2
|
|
WO2025120867A1
(en)
|
2023-12-08 |
2025-06-12 |
Astellas Pharma Inc. |
Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and anti-vegfr2 antibodies
|
|
WO2025129002A1
(en)
|
2023-12-13 |
2025-06-19 |
Incyte Corporation |
Bicyclooctane kras inhibitors
|
|
WO2025132479A1
(en)
|
2023-12-18 |
2025-06-26 |
Institut National de la Santé et de la Recherche Médicale |
Flt3 inhibitor for modulating macrophages polarization
|
|
WO2025132770A1
(en)
|
2023-12-22 |
2025-06-26 |
Institut National de la Santé et de la Recherche Médicale |
Affitins for the treatment of cancer
|
|
WO2025145207A1
(en)
|
2023-12-29 |
2025-07-03 |
Bristol-Myers Squibb Company |
Combination therapy of kras inhibitor and treg-depleting agent
|
|
TW202539700A
(zh)
|
2024-01-16 |
2025-10-16 |
美商建南德克公司 |
用pd-1軸結合拮抗劑及rna疫苗治療泌尿上皮癌之方法
|
|
WO2025153834A1
(en)
|
2024-01-19 |
2025-07-24 |
Institut National de la Santé et de la Recherche Médicale |
Methods of predicting the risk of recurrence and/or death of patients suffering from a hepatocellular carcinoma (hcc)
|
|
WO2025163468A1
(en)
|
2024-01-30 |
2025-08-07 |
Seagen Inc. |
Anti-pd-l1 antibodies and antibody-drug conjugates and their use in the treatment of cancer
|
|
WO2025174825A2
(en)
|
2024-02-12 |
2025-08-21 |
Aera Therapeutics, Inc. |
Delivery compositions
|
|
WO2025174933A1
(en)
|
2024-02-14 |
2025-08-21 |
Genentech, Inc. |
Methods for treatment of pancreatic cancer with anti-pd-l1 ab, anti-tigit ab, gemcitabine and nab-placlitaxel
|
|
EP4658320A1
(en)
|
2024-02-27 |
2025-12-10 |
Bristol-Myers Squibb Company |
Anti-ceacam5 antibody drug conjugates
|
|
WO2025184208A1
(en)
|
2024-02-27 |
2025-09-04 |
Bristol-Myers Squibb Company |
Anti-ceacam5 antibodies and uses thereof
|
|
WO2025188693A1
(en)
|
2024-03-05 |
2025-09-12 |
Bristol-Myers Squibb Company |
Bicyclic tlr7 agonists and uses thereof
|
|
WO2025188694A1
(en)
|
2024-03-05 |
2025-09-12 |
Bristol-Myers Squibb Company |
Tricyclic tlr7 agonists and uses thereof
|
|
WO2025186778A1
(en)
|
2024-03-08 |
2025-09-12 |
Janssen Biotech, Inc. |
Combinations of oncolytic viruses and immunomodulators
|
|
US20250361297A1
(en)
|
2024-03-12 |
2025-11-27 |
Adaptam Therapeutics, S.L. |
Anti- siglec-15 binding molecules and methods of use
|
|
WO2025191529A1
(en)
|
2024-03-14 |
2025-09-18 |
Biohaven Therapeutics Ltd. |
Next generation riluzole prodrugs
|
|
WO2025202213A1
(en)
|
2024-03-26 |
2025-10-02 |
Institut National de la Santé et de la Recherche Médicale |
Lipid nanoparticle loaded with antitumoral agent and functionnalized to target immosuppressive cells
|
|
WO2025210123A1
(en)
|
2024-04-03 |
2025-10-09 |
Institut National de la Santé et de la Recherche Médicale |
Methods and pharmaceutical composition for treating cancers
|
|
WO2025210175A1
(en)
|
2024-04-04 |
2025-10-09 |
Centre National De La Recherche Scientifique |
Mutant csf-1r extracellular domain fusion molecules and therapeutic uses thereof
|
|
WO2025213154A1
(en)
|
2024-04-05 |
2025-10-09 |
Amgen Inc. |
Gastrointestinal cancer treatments using mta-cooperative prmt5 inhibitors
|
|
WO2025216894A1
(en)
|
2024-04-09 |
2025-10-16 |
Sensei Biotherapeutics, Inc. |
Bispecific anti-vista and anti-cd28 binding proteins and uses thereof
|
|
WO2025219330A1
(en)
|
2024-04-15 |
2025-10-23 |
Institut National de la Santé et de la Recherche Médicale |
Detection of ppix for use in methods for melanoma ferroptosis sensitivity and targeted therapy resistance prediction
|
|
WO2025219595A1
(en)
|
2024-04-19 |
2025-10-23 |
Biper Therapeutics |
Method for combination treatments using alkynylbenzenesulphonamides for cancer therapy
|
|
WO2025226767A1
(en)
|
2024-04-24 |
2025-10-30 |
Bristol-Myers Squibb Company |
Substituted 3-(5-(6-aminopyridin-2-yl)-4-fluoro-1-oxoisoindolin-2-yl)piperidine-2,6-dione compounds for use in the treatment of cancer
|
|
WO2025228998A1
(en)
|
2024-04-30 |
2025-11-06 |
Institut National de la Santé et de la Recherche Médicale |
Use of hdac4 inhibitors for the treatment of melanoma
|
|
WO2025232879A1
(en)
|
2024-05-10 |
2025-11-13 |
Cytocares (Shanghai) Inc. |
Anti-lilrb2 monospecific and bispecific antibody constructs and uses thereof
|
|
WO2025233867A1
(en)
|
2024-05-10 |
2025-11-13 |
Adaptam Therapeutics, S.L. |
Anti-siglec-9 antibodies and uses thereof
|
|
WO2025245489A1
(en)
|
2024-05-24 |
2025-11-27 |
Bristol-Myers Squibb Company |
Treatment of tumors in subjects having fgl-1 positive samples
|
|
WO2025247829A1
(en)
|
2024-05-27 |
2025-12-04 |
Institut National de la Santé et de la Recherche Médicale |
Methods and pharmaceutical composition for treating prostate cancer
|
|
NL2037811B1
(en)
|
2024-05-29 |
2025-12-12 |
Univ Oslo |
Treatment for Cancer
|
|
WO2025254987A1
(en)
|
2024-06-03 |
2025-12-11 |
Alector Llc |
Siglec-9 ecd fusion molecule variants and methods of use thereof
|
|
WO2025252857A1
(en)
|
2024-06-05 |
2025-12-11 |
Institut National de la Santé et de la Recherche Médicale |
Il-15 muteins with ph-dependent binding for il-15ralpha
|
|
WO2025252855A1
(en)
|
2024-06-05 |
2025-12-11 |
Institut National de la Santé et de la Recherche Médicale |
IL-15 MUTEINS WITH PH-DEPENDENT BINDING FOR IL-15Rbeta
|
|
GB202408360D0
(en)
|
2024-06-11 |
2024-07-24 |
Cancer Research Tech Ltd |
Tumour sensitisation
|
|
WO2025259515A2
(en)
|
2024-06-11 |
2025-12-18 |
Amgen Inc. |
Combination treatment
|
|
WO2026003224A2
(en)
|
2024-06-26 |
2026-01-02 |
Iomx Therapeutics Ag |
Bispecific antigen binding proteins (abp) targeting immune checkpoint molecules and both leukocyte immunoglobulin-like receptor subfamily b1 (lilrb1) and lilrb2; combinations and uses thereof
|
|
WO2026006604A1
(en)
|
2024-06-26 |
2026-01-02 |
Lyell Immunopharma, Inc. |
Feeder cell replacement
|