US7943743B2 - Human monoclonal antibodies to programmed death ligand 1 (PD-L1) - Google Patents

Human monoclonal antibodies to programmed death ligand 1 (PD-L1) Download PDF

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Publication number
US7943743B2
US7943743B2 US11/917,727 US91772706A US7943743B2 US 7943743 B2 US7943743 B2 US 7943743B2 US 91772706 A US91772706 A US 91772706A US 7943743 B2 US7943743 B2 US 7943743B2
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Prior art keywords
variable region
chain variable
seq id
amino acids
set forth
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US11/917,727
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US20090055944A1 (en
Inventor
Alan J. Korman
Mark J. Selby
Changyu Wang
Mohan Srinivasan
David B. Passmore
Haichun Huang
Haibin Chen
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ER Squibb and Sons LLC
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Medarex LLC
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Priority to US69642605P priority Critical
Application filed by Medarex LLC filed Critical Medarex LLC
Priority to PCT/US2006/026046 priority patent/WO2007005874A2/en
Priority to US11/917,727 priority patent/US7943743B2/en
Assigned to MEDAREX, INC. reassignment MEDAREX, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: CHEN, HAIBIN, WANG, CHANGYU, PASSMORE, DAVID B., SELBY, MARK J., SRINIVASAN, MOHAN, HUANG, HAICHUN, KORMAN, ALAN J.
Publication of US20090055944A1 publication Critical patent/US20090055944A1/en
Assigned to MEDAREX, INC. reassignment MEDAREX, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: KORMAN, ALAN J., PASSMORE, DAVID, HUANG, HAICHUN, SRINIVASAN, MOHAN, CHEN, HAIBIN, SELBY, MARK J., WANG, CHANGYU
Publication of US7943743B2 publication Critical patent/US7943743B2/en
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Assigned to MEDAREX, L.L.C. reassignment MEDAREX, L.L.C. MERGER (SEE DOCUMENT FOR DETAILS). Assignors: MEDAREX, INC.
Assigned to E. R. SQUIBB & SONS, L.L.C. reassignment E. R. SQUIBB & SONS, L.L.C. MERGER (SEE DOCUMENT FOR DETAILS). Assignors: MEDAREX, L.L.C.
Application status is Active legal-status Critical
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