CA2868393A1 - Modified polynucleotides for the production of oncology-related proteins and peptides - Google Patents

Modified polynucleotides for the production of oncology-related proteins and peptides Download PDF

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Publication number
CA2868393A1
CA2868393A1 CA2868393A CA2868393A CA2868393A1 CA 2868393 A1 CA2868393 A1 CA 2868393A1 CA 2868393 A CA2868393 A CA 2868393A CA 2868393 A CA2868393 A CA 2868393A CA 2868393 A1 CA2868393 A1 CA 2868393A1
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CA
Canada
Prior art keywords
cancer
oncology
isolated polynucleotide
thio
guanosine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2868393A
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English (en)
French (fr)
Inventor
Stephane Bancel
Tirtha Chakraborty
Antonin De Fougerolles
Sayda M. ELBASHIR
Matthias John
Atanu Roy
Susan Whoriskey
Kristy M. WOOD
Paul Hatala
Jason P. SCHRUM
Kenechi Ejebe
Jeff Lynn Ellsworth
Justin Guild
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Moderna Inc
Original Assignee
Moderna Therapeutics Inc
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49235350&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2868393(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Moderna Therapeutics Inc filed Critical Moderna Therapeutics Inc
Publication of CA2868393A1 publication Critical patent/CA2868393A1/en
Abandoned legal-status Critical Current

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    • A61K48/0066Manipulation of the nucleic acid to modify its expression pattern, e.g. enhance its duration of expression, achieved by the presence of particular introns in the delivered nucleic acid
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    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/7115Nucleic acids or oligonucleotides having modified bases, i.e. other than adenine, guanine, cytosine, uracil or thymine
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CA2868393A 2012-04-02 2013-03-09 Modified polynucleotides for the production of oncology-related proteins and peptides Abandoned CA2868393A1 (en)

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