ATE443528T1 - Erhöhter transport unter benutzung membranzerstörender stoffe - Google Patents

Erhöhter transport unter benutzung membranzerstörender stoffe

Info

Publication number
ATE443528T1
ATE443528T1 AT99900750T AT99900750T ATE443528T1 AT E443528 T1 ATE443528 T1 AT E443528T1 AT 99900750 T AT99900750 T AT 99900750T AT 99900750 T AT99900750 T AT 99900750T AT E443528 T1 ATE443528 T1 AT E443528T1
Authority
AT
Austria
Prior art keywords
agents
stimuli
agent
therapeutic
delivered
Prior art date
Application number
AT99900750T
Other languages
English (en)
Inventor
Allan Hoffman
Patrick Stayton
Oliver Press
David Tirrell
Niren Murthy
Chantal Lackey
Lawrence Crum
Pierre Mourad
Tyrone Porter
Original Assignee
Univ Washington
Univ Massachusetts
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Washington, Univ Massachusetts filed Critical Univ Washington
Application granted granted Critical
Publication of ATE443528T1 publication Critical patent/ATE443528T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0047—Sonopheresis, i.e. ultrasonically-enhanced transdermal delivery, electroporation of a pharmacologically active agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0028—Disruption, e.g. by heat or ultrasounds, sonophysical or sonochemical activation, e.g. thermosensitive or heat-sensitive liposomes, disruption of calculi with a medicinal preparation and ultrasounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT99900750T 1998-01-05 1999-01-05 Erhöhter transport unter benutzung membranzerstörender stoffe ATE443528T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7041198P 1998-01-05 1998-01-05
PCT/US1999/000122 WO1999034831A1 (en) 1998-01-05 1999-01-05 Enhanced transport using membrane disruptive agents

Publications (1)

Publication Number Publication Date
ATE443528T1 true ATE443528T1 (de) 2009-10-15

Family

ID=22095139

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99900750T ATE443528T1 (de) 1998-01-05 1999-01-05 Erhöhter transport unter benutzung membranzerstörender stoffe

Country Status (9)

Country Link
US (5) US6835393B2 (de)
EP (2) EP1044021B1 (de)
JP (1) JP2002500201A (de)
AT (1) ATE443528T1 (de)
AU (1) AU758368B2 (de)
CA (1) CA2317549C (de)
DE (1) DE69941447D1 (de)
ES (1) ES2356342T3 (de)
WO (1) WO1999034831A1 (de)

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EP1044021A1 (de) 2000-10-18
US6835393B2 (en) 2004-12-28
US8846106B2 (en) 2014-09-30
ES2356342T3 (es) 2011-04-07
US8003129B2 (en) 2011-08-23
US20010007666A1 (en) 2001-07-12
US20110288238A1 (en) 2011-11-24
WO1999034831A1 (en) 1999-07-15
CA2317549A1 (en) 1999-07-15
DE69941447D1 (de) 2009-11-05
US20140219950A1 (en) 2014-08-07
CA2317549C (en) 2006-04-11
US7374778B2 (en) 2008-05-20
EP2138191A1 (de) 2009-12-30
AU2026199A (en) 1999-07-26
EP1044021B1 (de) 2009-09-23
AU758368B2 (en) 2003-03-20
JP2002500201A (ja) 2002-01-08
US20080199957A1 (en) 2008-08-21
US20050136102A1 (en) 2005-06-23

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