DE69517585D1 - Elektrotransport-abgabeeinrichtung mit erhöhter wirkstoffabgabe - Google Patents

Elektrotransport-abgabeeinrichtung mit erhöhter wirkstoffabgabe

Info

Publication number
DE69517585D1
DE69517585D1 DE69517585T DE69517585T DE69517585D1 DE 69517585 D1 DE69517585 D1 DE 69517585D1 DE 69517585 T DE69517585 T DE 69517585T DE 69517585 T DE69517585 T DE 69517585T DE 69517585 D1 DE69517585 D1 DE 69517585D1
Authority
DE
Germany
Prior art keywords
electrotransport
ion exchange
exchange material
active substance
dispersed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69517585T
Other languages
English (en)
Other versions
DE69517585T2 (de
Inventor
Joseph B Phipps
Lyn C Moodie
J Richard Gyory
Felix Theeuwes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Application granted granted Critical
Publication of DE69517585D1 publication Critical patent/DE69517585D1/de
Publication of DE69517585T2 publication Critical patent/DE69517585T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0448—Drug reservoir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0444—Membrane

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Electrotherapy Devices (AREA)
  • Medicinal Preparation (AREA)
  • Refuse Collection And Transfer (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medical Treatment And Welfare Office Work (AREA)
DE69517585T 1994-04-08 1995-04-07 Elektrotransport-abgabeeinrichtung mit erhöhter wirkstoffabgabe Expired - Lifetime DE69517585T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22547094A 1994-04-08 1994-04-08
PCT/US1995/004037 WO1995027529A1 (en) 1994-04-08 1995-04-07 Electrotransport system with enhanced drug delivery

Publications (2)

Publication Number Publication Date
DE69517585D1 true DE69517585D1 (de) 2000-07-27
DE69517585T2 DE69517585T2 (de) 2001-03-01

Family

ID=22844996

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69517585T Expired - Lifetime DE69517585T2 (de) 1994-04-08 1995-04-07 Elektrotransport-abgabeeinrichtung mit erhöhter wirkstoffabgabe

Country Status (9)

Country Link
US (1) US5871460A (de)
EP (1) EP0754078B1 (de)
JP (1) JP3821842B2 (de)
AT (1) ATE193978T1 (de)
AU (1) AU2276195A (de)
DE (1) DE69517585T2 (de)
DK (1) DK0754078T3 (de)
ES (1) ES2150563T3 (de)
WO (1) WO1995027529A1 (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2286995A (en) * 1994-04-08 1995-10-30 Alza Corporation Electrotransport system with ion exchange competitive ion capture
JP3565903B2 (ja) * 1994-06-25 2004-09-15 久光製薬株式会社 イオントフォレーシス用電極構造体
US5882677A (en) * 1997-09-30 1999-03-16 Becton Dickinson And Company Iontophoretic patch with hydrogel reservoir
US20040109874A1 (en) * 1999-11-10 2004-06-10 Powderject Vaccines, Inc. Induction of mucosal immunity by vaccination via the skin route
US6591133B1 (en) * 2000-11-27 2003-07-08 Microlin Llc Apparatus and methods for fluid delivery using electroactive needles and implantable electrochemical delivery devices
DE10141650C1 (de) 2001-08-24 2002-11-28 Lohmann Therapie Syst Lts Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen
EE200400090A (et) * 2001-10-31 2004-10-15 R&R Ventures Incorporation Ionoforeesiseade
JP4606118B2 (ja) * 2004-10-21 2011-01-05 株式会社トクヤマ イオントフォレーシス装置用作用極構造体の製造方法
US20060095001A1 (en) * 2004-10-29 2006-05-04 Transcutaneous Technologies Inc. Electrode and iontophoresis device
JP4728631B2 (ja) * 2004-11-30 2011-07-20 Ｔｔｉ・エルビュー株式会社 イオントフォレーシス装置
US7590444B2 (en) * 2004-12-09 2009-09-15 Tti Ellebeau, Inc. Iontophoresis device
JP4731931B2 (ja) * 2005-02-03 2011-07-27 Ｔｔｉ・エルビュー株式会社 イオントフォレーシス装置
JP4793806B2 (ja) * 2005-03-22 2011-10-12 Ｔｔｉ・エルビュー株式会社 イオントフォレーシス装置
JP2006296511A (ja) * 2005-04-15 2006-11-02 Transcutaneous Technologies Inc 外用剤、外用剤の塗布方法、イオントフォレーシス装置及び経皮パッチ
JP5189485B2 (ja) * 2005-04-22 2013-04-24 イーシーポイント メディカル インコーポレイテッド Ｄｃ組織処置
JP2006334164A (ja) * 2005-06-02 2006-12-14 Transcutaneous Technologies Inc イオントフォレーシス装置及びその制御方法
JP2006346368A (ja) * 2005-06-20 2006-12-28 Transcutaneous Technologies Inc イオントフォレーシス装置及びその製造方法
US20070027426A1 (en) * 2005-06-24 2007-02-01 Transcutaneous Technologies Inc. Iontophoresis device to deliver active agents to biological interfaces
US20070025869A1 (en) * 2005-07-15 2007-02-01 Gordon John H Fluid Delivery Device
US8386030B2 (en) * 2005-08-08 2013-02-26 Tti Ellebeau, Inc. Iontophoresis device
US20070088331A1 (en) * 2005-08-18 2007-04-19 Transcutaneous Technologies Inc. Method and apparatus for managing active agent usage, and active agent injecting device
CA2619665A1 (en) * 2005-09-15 2007-03-22 Tti Ellebeau, Inc. Rod type iontophoresis device
JP2009509657A (ja) * 2005-09-30 2009-03-12 Ｔｔｉ・エルビュー株式会社 生体界面への活性物質の送達のイオントフォレーシス装置及び方法
WO2007041526A2 (en) * 2005-09-30 2007-04-12 Transcutaneous Technologies Inc. Iontophoresis apparatus and method to deliver antibiotics to biological interfaces
KR20080066712A (ko) * 2005-09-30 2008-07-16 티티아이 엘뷰 가부시키가이샤 관능화된 미세바늘 경피 약물 전달 시스템, 장치 및 방법
US20080147186A1 (en) * 2006-12-14 2008-06-19 Joshi Ashok V Electrochemical Implant For Delivering Beneficial Agents
US20080188791A1 (en) * 2007-02-02 2008-08-07 Difiore Attilio E Active iontophoresis delivery system
US8197844B2 (en) * 2007-06-08 2012-06-12 Activatek, Inc. Active electrode for transdermal medicament administration
US8862223B2 (en) 2008-01-18 2014-10-14 Activatek, Inc. Active transdermal medicament patch and circuit board for same
US8190252B2 (en) 2009-02-12 2012-05-29 Incube Labs, Llc Iontophoretic system for transdermal delivery of active agents for therapeutic and medicinal purposes
BRPI1013399A2 (pt) 2009-02-26 2016-04-05 Liquidia Technologies Inc sistema de entrega de fármaco intervencional e métodos associados
US8903485B2 (en) 2009-08-06 2014-12-02 Incube Labs, Llc Patch and patch assembly for iontophoretic transdermal delivery of active agents for therapeutic and medicinal purposes
EP2688639B1 (de) 2011-03-24 2019-09-18 Incube Labs, Llc System zur zweiphasigen transdermalen iontophoretischen abgabe von therapiemitteln
JP2014036766A (ja) * 2012-08-17 2014-02-27 Hitachi Maxell Ltd 美容機器
WO2015017467A2 (en) 2013-07-29 2015-02-05 Kural Corp. Therapeutic electron and ion transfer via half-cell
WO2020037294A1 (en) * 2018-08-17 2020-02-20 Incube Labs, Llc System and method for biphasic transdermal iontophoretic delivery of diclophenac and other therapeutic agents

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE399044A (de) * 1933-09-09
US5135477A (en) * 1984-10-29 1992-08-04 Medtronic, Inc. Iontophoretic drug delivery
US4747819A (en) * 1984-10-29 1988-05-31 Medtronic, Inc. Iontophoretic drug delivery
US4744787A (en) * 1984-10-29 1988-05-17 Medtronic, Inc. Iontophoresis apparatus and methods of producing same
US4585652A (en) * 1984-11-19 1986-04-29 Regents Of The University Of Minnesota Electrochemical controlled release drug delivery system
US4722726A (en) * 1986-02-12 1988-02-02 Key Pharmaceuticals, Inc. Method and apparatus for iontophoretic drug delivery
US4915685A (en) * 1986-03-19 1990-04-10 Petelenz Tomasz J Methods and apparatus for iontophoresis application of medicaments at a controlled ph through ion exchange
US4731049A (en) * 1987-01-30 1988-03-15 Ionics, Incorporated Cell for electrically controlled transdermal drug delivery
US5162042A (en) * 1988-07-05 1992-11-10 Alza Corporation Electrotransport transdermal system
US4927408A (en) * 1988-10-03 1990-05-22 Alza Corporation Electrotransport transdermal system
US5057072A (en) * 1988-10-28 1991-10-15 Medtronic, Inc. Iontophoresis electrode
US5084008A (en) * 1989-12-22 1992-01-28 Medtronic, Inc. Iontophoresis electrode
US5084006A (en) * 1990-03-30 1992-01-28 Alza Corporation Iontopheretic delivery device
WO1991015260A1 (en) * 1990-03-30 1991-10-17 Alza Corporation Device and method for iontophoretic drug delivery
US5125894A (en) * 1990-03-30 1992-06-30 Alza Corporation Method and apparatus for controlled environment electrotransport
US5147297A (en) * 1990-05-07 1992-09-15 Alza Corporation Iontophoretic delivery device
EP0643600B1 (de) * 1992-06-02 1997-10-15 Alza Corporation Vorrichtung zur iontophoretischen verabreichung von medikamenten

Also Published As

Publication number Publication date
ES2150563T3 (es) 2000-12-01
DE69517585T2 (de) 2001-03-01
DK0754078T3 (da) 2000-10-02
ATE193978T1 (de) 2000-07-15
JP3821842B2 (ja) 2006-09-13
WO1995027529A1 (en) 1995-10-19
EP0754078A1 (de) 1997-01-22
US5871460A (en) 1999-02-16
EP0754078B1 (de) 2000-06-21
JPH09511664A (ja) 1997-11-25
AU2276195A (en) 1995-10-30

Similar Documents

Publication Publication Date Title
DE69517585D1 (de) Elektrotransport-abgabeeinrichtung mit erhöhter wirkstoffabgabe
AU2426792A (en) Transdermal delivery device
DK0531284T3 (da) Fremgangsmåde og apparat til iontoforetisk medikamentafgivelse
NO157544C (no) Fremgangsmaate for i en elektrolyseanordning aa fordele den elektriske stroemmen over en elastisk, poroes og permeabel elektrodes overflate, samt elektrolyseanordning.
KR960704597A (ko) 이온 전기 도입법에 의해 촉진되는 전달에 사용하기 위한 일회용 투여 유닛(Disposable Dosage Unit for lontophoresis-Facilitated Delivery)
DK161688D0 (da) Iontoterapeutisk apparat og proces og enhedsdosis
ES2082423T3 (es) Dispositivo para la distribucion transcutanea de farmacos.
NO923770D0 (no) Apparat og fremgangsmaate for iontoforetisk medikamenttilfoersel
NO914893L (no) Anordning og fremgangsmaate for fornyelse av elektroder under iontoforese
ES2012944A6 (es) Procedimiento y su dispositivo para la admionistracion de farmacos mediante ionoforesis, para tratamiento loco-regionales.
AU1299795A (en) Electrotransport delivery device and method of making same
PT100737A (pt) Sistemas terapeuticos transcutaneos e processo para a sua preparacao
IL103711A0 (en) Drug delivery device
DE69512083T2 (de) Vorrichtung zur erhöhung der wirkstoffsverabreichung durch elektrotransport
DK33790D0 (da) Elektrotransportklaebemiddel
PT941085E (pt) Dispositivo para administracao electricamente assistida de agentes como a lidocaina e a epinefrina
AU6100194A (en) Active drug delivery device, electrode, and method for making same
DK0574450T3 (da) Anordning til kontinuerlig elektrodeløs elektrokemisk behandling af et elektrisk ledende væv i en elektrolytcelle og anvendelse heraf

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: KUDLEK & GRUNERT PATENTANWAELTE PARTNERSCHAFT, 803