US172808A
(en)
*
|
|
1876-01-25 |
|
Improvement in balanced valves |
US5563250A
(en)
|
1987-12-02 |
1996-10-08 |
Neorx Corporation |
Cleavable conjugates for the delivery and release of agents in native form
|
US6140496A
(en)
|
1990-10-09 |
2000-10-31 |
Benner; Steven Albert |
Precursors for deoxyribonucleotides containing non-standard nucleosides
|
US5505931A
(en)
|
1993-03-04 |
1996-04-09 |
The Dow Chemical Company |
Acid cleavable compounds, their preparation and use as bifunctional acid-labile crosslinking agents
|
US5681702A
(en)
|
1994-08-30 |
1997-10-28 |
Chiron Corporation |
Reduction of nonspecific hybridization by using novel base-pairing schemes
|
US5585108A
(en)
|
1994-12-30 |
1996-12-17 |
Nanosystems L.L.C. |
Formulations of oral gastrointestinal therapeutic agents in combination with pharmaceutically acceptable clays
|
US5795587A
(en)
|
1995-01-23 |
1998-08-18 |
University Of Pittsburgh |
Stable lipid-comprising drug delivery complexes and methods for their production
|
US6265389B1
(en)
|
1995-08-31 |
2001-07-24 |
Alkermes Controlled Therapeutics, Inc. |
Microencapsulation and sustained release of oligonucleotides
|
US6214966B1
(en)
|
1996-09-26 |
2001-04-10 |
Shearwater Corporation |
Soluble, degradable poly(ethylene glycol) derivatives for controllable release of bound molecules into solution
|
US20030073640A1
(en)
|
1997-07-23 |
2003-04-17 |
Ribozyme Pharmaceuticals, Inc. |
Novel compositions for the delivery of negatively charged molecules
|
US6426086B1
(en)
|
1998-02-03 |
2002-07-30 |
The Regents Of The University Of California |
pH-sensitive, serum-stable liposomes
|
US7521178B1
(en)
|
1998-04-23 |
2009-04-21 |
Takara Bio Inc. |
Method for synthesizing DNA
|
DE60020677T2
(de)
|
1999-02-26 |
2006-05-04 |
Chiron Corp., Emeryville |
Mikroemulsionen mit adsorbierten makromolekülen und mikropartikeln
|
EP1102785B1
(en)
|
1999-06-07 |
2013-02-13 |
Arrowhead Research Corporation |
COMPOSITIONS FOR DRUG DELIVERY USING pH SENSITIVE MOLECULES
|
US7098032B2
(en)
|
2001-01-02 |
2006-08-29 |
Mirus Bio Corporation |
Compositions and methods for drug delivery using pH sensitive molecules
|
EP1792991A1
(en)
|
1999-08-24 |
2007-06-06 |
Medarex, Inc. |
Human CTLA-4 antibodies and their uses
|
US6998115B2
(en)
|
2000-10-10 |
2006-02-14 |
Massachusetts Institute Of Technology |
Biodegradable poly(β-amino esters) and uses thereof
|
US6649138B2
(en)
|
2000-10-13 |
2003-11-18 |
Quantum Dot Corporation |
Surface-modified semiconductive and metallic nanoparticles having enhanced dispersibility in aqueous media
|
US7708915B2
(en)
|
2004-05-06 |
2010-05-04 |
Castor Trevor P |
Polymer microspheres/nanospheres and encapsulating therapeutic proteins therein
|
US6897196B1
(en)
|
2001-02-07 |
2005-05-24 |
The Regents Of The University Of California |
pH sensitive lipids based on ortho ester linkers, composition and method
|
WO2003011443A2
(en)
|
2001-07-27 |
2003-02-13 |
President And Fellows Of Harvard College |
Laminar mixing apparatus and methods
|
CA2462593A1
(en)
|
2001-10-03 |
2003-04-10 |
Kam W. Leong |
Compositions for oral gene therapy and methods of using same
|
WO2003042383A1
(fr)
|
2001-11-14 |
2003-05-22 |
Toyo Boseki Kabushiki Kaisha |
Promoteurs de replication de l'adn, facteurs associes a l'adn polymerase et utilisation de ces derniers
|
CA2409775C
(en)
|
2001-12-03 |
2010-07-13 |
F. Hoffmann-La Roche Ag |
Reversibly modified thermostable enzymes for dna synthesis and amplification in vitro
|
SI1474109T1
(sl)
|
2001-12-21 |
2010-11-30 |
Alcon Inc |
Uporaba sintetičnih anorganskih nanodelcev kot nosilcev za oftalmična zdravila
|
US20050222064A1
(en)
|
2002-02-20 |
2005-10-06 |
Sirna Therapeutics, Inc. |
Polycationic compositions for cellular delivery of polynucleotides
|
WO2003075892A1
(en)
|
2002-03-13 |
2003-09-18 |
Novartis Ag |
Pharmaceutical microparticles
|
WO2003092665A2
(en)
|
2002-05-02 |
2003-11-13 |
Massachusetts Eye And Ear Infirmary |
Ocular drug delivery systems and use thereof
|
WO2005007819A2
(en)
|
2003-07-09 |
2005-01-27 |
Wisconsin Alumni Research Foundation |
Charge-dynamic polymers and delivery of anionic compounds
|
WO2005072710A2
(en)
|
2004-01-28 |
2005-08-11 |
Johns Hopkins University |
Drugs and gene carrier particles that rapidly move through mucous barriers
|
CN101084016A
(zh)
|
2004-04-15 |
2007-12-05 |
克艾思马有限公司 |
能够容易穿透生物学障碍的组合物
|
WO2005123114A2
(en)
|
2004-06-11 |
2005-12-29 |
Trustees Of Tufts College |
Silk-based drug delivery system
|
US8354476B2
(en)
|
2004-12-10 |
2013-01-15 |
Kala Pharmaceuticals, Inc. |
Functionalized poly(ether-anhydride) block copolymers
|
US8192718B1
(en)
|
2005-01-04 |
2012-06-05 |
Gp Medical, Inc. |
Pharmaceutical composition of nanoparticles
|
AU2006336384B2
(en)
|
2005-02-14 |
2010-12-16 |
Sirna Therapeutics, Inc. |
Lipid nanoparticle based compositions and methods for the delivery of biologically active molecules
|
US7404969B2
(en)
|
2005-02-14 |
2008-07-29 |
Sirna Therapeutics, Inc. |
Lipid nanoparticle based compositions and methods for the delivery of biologically active molecules
|
MX2007012157A
(es)
|
2005-04-01 |
2008-03-14 |
Intezyne Technologies Llc |
Micelas polimericas para suministro de farmacos.
|
EP1885403B1
(en)
|
2005-04-12 |
2013-05-08 |
Nektar Therapeutics |
Poly(ethyleneglycol) conjugates of Lysostaphin
|
KR101339628B1
(ko)
|
2005-05-09 |
2013-12-09 |
메다렉스, 인코포레이티드 |
예정 사멸 인자 1(pd-1)에 대한 인간 모노클로날 항체, 및 항-pd-1 항체를 단독 사용하거나 기타 면역 요법제와 병용한 암 치료 방법
|
US7550264B2
(en)
|
2005-06-10 |
2009-06-23 |
Datascope Investment Corporation |
Methods and kits for sense RNA synthesis
|
PT2279758E
(pt)
|
2005-06-16 |
2015-05-27 |
Nektar Therapeutics |
Conjugados possuindo uma ligação degradável e reagentes poliméricos úteis na preparação de tais conjugados
|
JP5570721B2
(ja)
|
2005-06-17 |
2014-08-13 |
ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル |
ナノ粒子の製造方法、システム、及び材料
|
US8105813B2
(en)
|
2005-06-30 |
2012-01-31 |
Archemix Corp. |
Materials and methods for the generation of fully 2′-modified nucleic acid transcripts
|
US8101385B2
(en)
|
2005-06-30 |
2012-01-24 |
Archemix Corp. |
Materials and methods for the generation of transcripts comprising modified nucleotides
|
KR101888321B1
(ko)
|
2005-07-01 |
2018-08-13 |
이. 알. 스퀴부 앤드 선즈, 엘.엘.씨. |
예정 사멸 리간드 1 (피디-엘1)에 대한 인간 모노클로날 항체
|
DE102005046490A1
(de)
|
2005-09-28 |
2007-03-29 |
Johannes-Gutenberg-Universität Mainz |
Modifikationen von RNA, die zu einer erhöhten Transkriptstabilität und Translationseffizienz führen
|
EP1986695B1
(en)
|
2006-02-21 |
2015-06-03 |
Nektar Therapeutics |
Segmented degradable polymers and conjugates made therefrom
|
AU2007240986A1
(en)
|
2006-04-04 |
2007-11-01 |
Stc.Unm |
Swellable particles for drug delivery
|
CA2647282A1
(en)
|
2006-04-05 |
2007-10-11 |
Pfizer Products Inc. |
Ctla4 antibody combination therapy
|
JP5630998B2
(ja)
|
2006-05-15 |
2014-11-26 |
マサチューセッツ インスティテュート オブ テクノロジー |
機能的粒子のためのポリマー
|
ES2360538T3
(es)
|
2006-09-08 |
2011-06-06 |
Johns Hopkins University |
Composiciones para aumentar el transporte a través de moco.
|
WO2008073558A2
(en)
|
2006-10-05 |
2008-06-19 |
The Johns Hopkins University |
Water-dispersible oral, parenteral, and topical formulations for poorly water soluble drugs using smart polymeric nanoparticles
|
US8399007B2
(en)
|
2006-12-05 |
2013-03-19 |
Landec Corporation |
Method for formulating a controlled-release pharmaceutical formulation
|
US8956602B2
(en)
|
2006-12-05 |
2015-02-17 |
Landec, Inc. |
Delivery of drugs
|
US20100184659A1
(en)
|
2006-12-21 |
2010-07-22 |
Warren Jaworowicz |
Sustained-Release Formulations Comprising Crystals, Macromolecular Gels, and Particulate Suspensions of Biologic Agents
|
WO2008078180A2
(en)
|
2006-12-22 |
2008-07-03 |
Archemix Corp. |
Materials and methods for the generation of transcripts comprising modified nucleotides
|
CA2689042A1
(en)
|
2007-02-16 |
2008-08-28 |
Merck & Co., Inc. |
Compositions and methods for potentiated activity of biologicaly active molecules
|
US7943168B2
(en)
|
2007-03-05 |
2011-05-17 |
Washington University |
Nanoparticle delivery systems comprising a hydrophobic core and a lipid/surfactant layer comprising a membrane-lytic peptide
|
EP3434259A1
(en)
|
2007-05-04 |
2019-01-30 |
Marina Biotech, Inc. |
Amino acid lipids and uses thereof
|
PL2170959T3
(pl)
|
2007-06-18 |
2014-03-31 |
Merck Sharp & Dohme |
Przeciwciała przeciwko ludzkiemu receptorowi programowanej śmierci PD-1
|
US20130108663A1
(en)
*
|
2007-09-14 |
2013-05-02 |
Vrije Universiteit Brussel |
Enhancing the t-cell stimulatory capacity of human antigen presenting cells in vitro and in vivo and their use in vaccination
|
CA2715078C
(en)
|
2007-09-26 |
2019-07-23 |
Intrexon Corporation |
Synthetic 5'utrs, expression vectors, and methods for increasing transgene expression
|
ES2647538T3
(es)
|
2007-09-28 |
2017-12-22 |
Pfizer Inc. |
Direccionamiento a células de cáncer usando nanopartículas
|
SG10201408162PA
(en)
|
2007-12-11 |
2015-01-29 |
Scripps Research Inst |
Compositions and methods related to mrna translational enhancer elements
|
DK2279254T3
(en)
|
2008-04-15 |
2017-09-18 |
Protiva Biotherapeutics Inc |
PRESENT UNKNOWN LIPID FORMS FOR NUCLEIC ACID ADMINISTRATION
|
DK2288336T3
(en)
|
2008-04-25 |
2017-03-13 |
Univ Northwestern |
NANOSTRUCTURES SUITABLE FOR COMPLEXATION OF CHOLESTEROL
|
PL215513B1
(pl)
|
2008-06-06 |
2013-12-31 |
Univ Warszawski |
Nowe boranofosforanowe analogi dinukleotydów, ich zastosowanie, czasteczka RNA, sposób otrzymywania RNA oraz sposób otrzymywania peptydów lub bialka
|
US8613951B2
(en)
|
2008-06-16 |
2013-12-24 |
Bind Therapeutics, Inc. |
Therapeutic polymeric nanoparticles with mTor inhibitors and methods of making and using same
|
SI2285350T1
(en)
|
2008-06-16 |
2018-03-30 |
Pfizer Inc. |
Methods for the preparation of diblock copolymers functionalized with targeting agent for use in the manufacture of therapeutic nanoparticles
|
JP2012501966A
(ja)
|
2008-06-16 |
2012-01-26 |
バインド バイオサイエンシズ インコーポレイテッド |
ビンカアルカロイド含有治療用ポリマーナノ粒子並びにその製造方法及び使用方法
|
ES2462090T5
(es)
|
2008-06-16 |
2017-07-12 |
Pfizer Inc. |
Nanopartículas poliméricas cargadas de fármaco y procedimientos de fabricación y uso de las mismas
|
US20110224447A1
(en)
|
2008-08-18 |
2011-09-15 |
Bowman Keith A |
Novel Lipid Nanoparticles and Novel Components for Delivery of Nucleic Acids
|
PL2350129T3
(pl)
|
2008-08-25 |
2015-12-31 |
Amplimmune Inc |
Kompozycje antagonistów PD-1 i sposoby stosowania
|
WO2010030763A2
(en)
|
2008-09-10 |
2010-03-18 |
Bind Biosciences, Inc. |
High throughput fabrication of nanoparticles
|
US20100075072A1
(en)
|
2008-09-25 |
2010-03-25 |
Tsung-Wei Chen |
Decorative structure of tree-shaped bells
|
US8969353B2
(en)
|
2008-11-07 |
2015-03-03 |
Massachusetts Institute Of Technology |
Aminoalcohol lipidoids and uses thereof
|
KR20210060670A
(ko)
|
2008-12-09 |
2021-05-26 |
제넨테크, 인크. |
항-pd-l1 항체 및 t 세포 기능을 향상시키기 위한 그의 용도
|
ES2776126T3
(es)
|
2008-12-15 |
2020-07-29 |
Pfizer |
Nanopartículas de circulación prolongada para la liberación sostenida de agentes terapéuticos
|
WO2010080724A1
(en)
|
2009-01-12 |
2010-07-15 |
Merck Sharp & Dohme Corp. |
Novel lipid nanoparticles and novel components for delivery of nucleic acids
|
WO2010087791A1
(en)
|
2009-01-27 |
2010-08-05 |
Utc Power Corporation |
Distributively cooled, integrated water-gas shift reactor and vaporizer
|
JP5596712B2
(ja)
|
2009-03-12 |
2014-09-24 |
イリノイ トゥール ワークス インコーポレイティド |
給油ミス防止装置
|
JP5622254B2
(ja)
|
2009-03-31 |
2014-11-12 |
国立大学法人東京大学 |
二本鎖リボ核酸ポリイオンコンプレックス
|
MX2011011134A
(es)
|
2009-04-21 |
2012-01-31 |
Selecta Biosciences Inc |
Agentes inmunonanoterapeuticos que proporcionan una respuesta sesgada hacia th1.
|
WO2010127159A2
(en)
|
2009-04-30 |
2010-11-04 |
Intezyne Technologies, Incorporated |
Polymeric micelles for polynucleotide encapsulation
|
DE202009007116U1
(de)
|
2009-05-18 |
2010-10-14 |
Amoena Medizin-Orthopädie-Technik GmbH |
Antidekubituskissen
|
KR20180026571A
(ko)
|
2009-05-27 |
2018-03-12 |
셀렉타 바이오사이언시즈, 인크. |
면역조절제를 pH 감응성으로 방출하는 표적화된 합성 나노운반체
|
TR201811076T4
(tr)
|
2009-06-10 |
2018-08-27 |
Arbutus Biopharma Corp |
Geliştirilmiş lipit formulasyonu.
|
WO2011000106A1
(en)
|
2009-07-01 |
2011-01-06 |
Protiva Biotherapeutics, Inc. |
Improved cationic lipids and methods for the delivery of therapeutic agents
|
ES2613498T3
(es)
|
2009-07-01 |
2017-05-24 |
Protiva Biotherapeutics Inc. |
Nuevas formulaciones de lípidos para el suministro de agentes terapéuticos a tumores sólidos
|
US9181295B2
(en)
|
2009-08-20 |
2015-11-10 |
Sirna Therapeutics, Inc. |
Cationic lipids with various head groups for oligonucleotide delivery
|
US20120253032A1
(en)
|
2009-10-08 |
2012-10-04 |
Merck Sharp & Dohme Corporation |
Novel cationic lipids with short lipid chains for oligonucleotide delivery
|
CN102712935B
(zh)
|
2009-11-04 |
2017-04-26 |
不列颠哥伦比亚大学 |
含有核酸的脂质粒子及相关的方法
|
US8449916B1
(en)
|
2009-11-06 |
2013-05-28 |
Iowa State University Research Foundation, Inc. |
Antimicrobial compositions and methods
|
GB0920304D0
(en)
|
2009-11-20 |
2010-01-06 |
Medical Res Council |
Novel liposome nanoparticles for tumour magnetic resonance imaging
|
US20130017199A1
(en)
|
2009-11-24 |
2013-01-17 |
AMPLIMMUNE ,Inc. a corporation |
Simultaneous inhibition of pd-l1/pd-l2
|
DK3338765T3
(en)
|
2009-12-01 |
2019-03-04 |
Translate Bio Inc |
STEROID DERIVATIVE FOR THE SUPPLY OF MRNA IN HUMANGENETIC DISEASES
|
WO2011069529A1
(en)
|
2009-12-09 |
2011-06-16 |
Curevac Gmbh |
Mannose-containing solution for lyophilization, transfection and/or injection of nucleic acids
|
WO2011072218A2
(en)
|
2009-12-11 |
2011-06-16 |
Bind Biosciences |
Stable formulations for lyophilizing therapeutic particles
|
US9295649B2
(en)
|
2009-12-15 |
2016-03-29 |
Bind Therapeutics, Inc. |
Therapeutic polymeric nanoparticle compositions with high glass transition temperature or high molecular weight copolymers
|
JP5898627B2
(ja)
|
2009-12-15 |
2016-04-06 |
バインド セラピューティックス インコーポレイテッド |
エポチロンを含む治療用ポリマーナノ粒子ならびにそれを製造および使用する方法
|
JP6175237B2
(ja)
|
2009-12-15 |
2017-08-02 |
ファイザー・インク |
コルチコステロイドを含む治療用ポリマーナノ粒およびそれを製造かつ使用する方法
|
DE102009058769A1
(de)
|
2009-12-16 |
2011-06-22 |
MagForce Nanotechnologies AG, 10589 |
Temperaturabhängige Aktivierung von katalytischen Nukleinsäuren zur kontrollierten Wirkstofffreisetzung
|
EA026374B1
(ru)
|
2009-12-23 |
2017-04-28 |
Новартис Аг |
Липиды, липидные композиции и способы их применения
|
WO2011090965A1
(en)
|
2010-01-22 |
2011-07-28 |
Merck Sharp & Dohme Corp. |
Novel cationic lipids for oligonucleotide delivery
|
WO2012082165A1
(en)
|
2010-01-24 |
2012-06-21 |
Novartis Ag |
Irradiated biodegradable polymer microparticles
|
US9149432B2
(en)
|
2010-03-19 |
2015-10-06 |
Massachusetts Institute Of Technology |
Lipid vesicle compositions and methods of use
|
WO2011119262A1
(en)
|
2010-03-26 |
2011-09-29 |
Cerulean Pharma Inc. |
Methods and systems for generating nanoparticles
|
EP2558074B1
(en)
|
2010-04-08 |
2018-06-06 |
The Trustees of Princeton University |
Preparation of lipid nanoparticles
|
EP2813220A3
(en)
|
2010-04-09 |
2015-06-17 |
Pacira Pharmaceuticals, Inc. |
Method for formulating large diameter synthetic membrane vesicles
|
US20110262491A1
(en)
|
2010-04-12 |
2011-10-27 |
Selecta Biosciences, Inc. |
Emulsions and methods of making nanocarriers
|
WO2011139911A2
(en)
|
2010-04-29 |
2011-11-10 |
Isis Pharmaceuticals, Inc. |
Lipid formulated single stranded rna
|
US9254327B2
(en)
|
2010-05-10 |
2016-02-09 |
Alnylam Pharmaceuticals, Inc. |
Methods and compositions for delivery of active agents
|
US20130123338A1
(en)
|
2010-05-12 |
2013-05-16 |
Protiva Biotherapeutics, Inc. |
Novel cationic lipids and methods of use thereof
|
JP2013531634A
(ja)
|
2010-05-24 |
2013-08-08 |
メルク・シャープ・エンド・ドーム・コーポレイション |
オリゴヌクレオチド送達のための新規なアミノアルコールカチオン性脂質
|
US9376679B2
(en)
|
2010-05-26 |
2016-06-28 |
Micromedmark Biotech Co. Ltd. |
Microvesicles carrying small interfering RNAs, preparation methods and uses thereof
|
WO2011153120A1
(en)
|
2010-06-04 |
2011-12-08 |
Merck Sharp & Dohme Corp. |
Novel low molecular weight cationic lipids for oligonucleotide delivery
|
BRPI1001959A2
(pt)
|
2010-06-15 |
2012-03-06 |
Instituto De Pesquisas Tecnológicas Do Est. S. Paulo S/a - Ipt |
Nanocarreadores coloidais para ativos hidrofílicos e processo de produção
|
US20130196948A1
(en)
|
2010-06-25 |
2013-08-01 |
Massachusetts Insitute Of Technology |
Polymers for biomaterials and therapeutics
|
EP4180057A1
(en)
|
2010-07-06 |
2023-05-17 |
GlaxoSmithKline Biologicals S.A. |
Virion-like delivery particles for self-replicating rna molecules
|
CN103327963A
(zh)
|
2010-07-06 |
2013-09-25 |
诺华股份有限公司 |
阳离子水包油乳液
|
BR112013000244A2
(pt)
|
2010-07-06 |
2016-05-17 |
Novartis Ag |
lipossomas com lipídeos apresentando pka vantajoso para administração de rna
|
DE102010032758B4
(de)
|
2010-07-29 |
2012-02-23 |
Fujitsu Technology Solutions Intellectual Property Gmbh |
Computersystem, Verfahren zum Programmieren einer Echtzeituhr und Computerprogrammprodukt
|
US8968746B2
(en)
|
2010-07-30 |
2015-03-03 |
Curevac Gmbh |
Complexation of nucleic acids with disulfide-crosslinked cationic components for transfection and immunostimulation
|
EP3578205A1
(en)
|
2010-08-06 |
2019-12-11 |
ModernaTX, Inc. |
A pharmaceutical formulation comprising engineered nucleic acids and medical use thereof
|
WO2012021516A2
(en)
|
2010-08-09 |
2012-02-16 |
The Trustees Of The University Of Pennsylvania |
Nanoparticle-oligonucletide hybrid structures and methods of use thereof
|
US8956646B2
(en)
|
2010-08-14 |
2015-02-17 |
The Regents Of The University Of California |
Zwitterionic lipids
|
MX2013002048A
(es)
|
2010-08-20 |
2013-07-03 |
Cerulean Pharma Inc |
Conjugados, particulas, composiciones y metodos relacionados.
|
PT2611467T
(pt)
|
2010-08-31 |
2022-08-01 |
Glaxosmithkline Biologicals Sa |
Lipossomas pequenos para entrega de arn que codifica um imunogénio
|
AU2011295935B2
(en)
|
2010-08-31 |
2016-02-11 |
Glaxosmithkline Biologicals S.A. |
Pegylated liposomes for delivery of immunogen-encoding RNA
|
ES2727583T3
(es)
|
2010-08-31 |
2019-10-17 |
Glaxosmithkline Biologicals Sa |
Lípidos adecuados para la administración liposómica de ARN que codifica proteínas
|
US10307372B2
(en)
|
2010-09-10 |
2019-06-04 |
The Johns Hopkins University |
Rapid diffusion of large polymeric nanoparticles in the mammalian brain
|
US8466122B2
(en)
|
2010-09-17 |
2013-06-18 |
Protiva Biotherapeutics, Inc. |
Trialkyl cationic lipids and methods of use thereof
|
ES2888231T3
(es)
|
2010-09-20 |
2022-01-03 |
Sirna Therapeutics Inc |
Lípidos catiónicos de bajo peso molecular para el suministro de oligonucleótidos
|
WO2012038448A1
(en)
|
2010-09-21 |
2012-03-29 |
Riboxx Gmbh |
Method for synthesizing rna using dna template
|
CA2811430A1
(en)
|
2010-09-30 |
2012-04-05 |
Merck Sharp & Dohme Corp. |
Low molecular weight cationic lipids for oligonucleotide delivery
|
US9782342B2
(en)
|
2010-10-11 |
2017-10-10 |
Wichita State University |
Composite magnetic nanoparticle drug delivery system
|
EP3485913A1
(en)
|
2010-10-21 |
2019-05-22 |
Sirna Therapeutics, Inc. |
Low molecular weight cationic lipids for oligonucleotide delivery
|
JP2013543844A
(ja)
|
2010-10-22 |
2013-12-09 |
バインド セラピューティックス インコーポレイテッド |
高分子コポリマーを含む治療用ナノ粒子
|
EP2635265B1
(en)
|
2010-11-05 |
2018-04-04 |
Sirna Therapeutics, Inc. |
Novel low molecular weight cyclic amine containing cationic lipids for oligonucleotide delivery
|
WO2012061703A1
(en)
|
2010-11-05 |
2012-05-10 |
The Johns Hopkins University |
Compositions and methods relating to reduced mucoadhesion
|
WO2012092552A1
(en)
|
2010-12-30 |
2012-07-05 |
Selecta Biosciences, Inc. |
Synthetic nanocarriers with reactive groups that release biologically active agents
|
EP2663548B1
(en)
|
2011-01-11 |
2017-04-05 |
Alnylam Pharmaceuticals, Inc. |
Pegylated lipids and their use for drug delivery
|
DE102011082231A1
(de)
|
2011-01-12 |
2012-07-12 |
Robert Bosch Gmbh |
Zündspule, insbesondere für kleinbauende Motoren
|
US20120189700A1
(en)
|
2011-01-19 |
2012-07-26 |
Zoraida Aguilar |
Nanoparticle Based Immunological Stimulation
|
US20140066363A1
(en)
|
2011-02-07 |
2014-03-06 |
Arun K. Bhunia |
Carbohydrate nanoparticles for prolonged efficacy of antimicrobial peptide
|
US8846850B2
(en)
|
2011-02-22 |
2014-09-30 |
Rutgers, The State University Of New Jersey |
Amphiphilic macromolecules for nucleic acid delivery
|
CA2828940C
(en)
|
2011-03-10 |
2024-04-16 |
Provectus Pharmaceuticals, Inc. |
Combination of local and systemic immunomodulative therapies for enhanced treatment of cancer
|
EA201391392A1
(ru)
|
2011-03-25 |
2014-04-30 |
Селекта Байосайенсиз, Инк. |
Синтетические наноносители с осмотически опосредованным высвобождением
|
AU2012237260A1
(en)
|
2011-03-31 |
2013-11-14 |
Ingell Technologies Holding B.V. |
Biodegradable compositions suitable for controlled release
|
CA2831471C
(en)
|
2011-03-31 |
2020-02-25 |
Ingell Technologies Holding B.V. |
Biodegradable compositions suitable for controlled release
|
JP2014511687A
(ja)
|
2011-03-31 |
2014-05-19 |
モデルナ セラピューティクス インコーポレイテッド |
工学操作された核酸の送達および製剤
|
EP3679933A1
(en)
|
2011-04-29 |
2020-07-15 |
Selecta Biosciences, Inc. |
Tolerogenic synthetic nanocarriers to reduce immune responses to therapeutic proteins
|
US20120283503A1
(en)
|
2011-04-29 |
2012-11-08 |
The Johns Hopkins University |
Nanoparticle loaded stem cells and their use in mri guided hyperthermia
|
US8691750B2
(en)
|
2011-05-17 |
2014-04-08 |
Axolabs Gmbh |
Lipids and compositions for intracellular delivery of biologically active compounds
|
US20140308363A1
(en)
|
2011-05-31 |
2014-10-16 |
Bind Therapeutics, Inc. |
Drug loaded polymeric nanoparticles and methods of making and using same
|
CA2873404C
(en)
|
2011-06-02 |
2022-08-30 |
The Regents Of The University Of California |
Membrane encapsulated nanoparticles and method of use
|
PL2717893T3
(pl)
|
2011-06-08 |
2019-12-31 |
Translate Bio, Inc. |
Kompozycje nanocząstek lipidowych i sposoby do dostarczania mRNA
|
ES2795110T3
(es)
|
2011-06-08 |
2020-11-20 |
Translate Bio Inc |
Lípidos escindibles
|
SG10201605537XA
(en)
|
2011-07-06 |
2016-09-29 |
Novartis Ag |
Liposomes having useful n:p ratio for delivery of rna molecules
|
DK2729462T3
(en)
|
2011-07-08 |
2018-01-08 |
Bayer Ip Gmbh |
PROCEDURE FOR PREPARING TETRAZOLE-SUBSTITUTED ANTHRANILY ACID DIAMIDE DERIVATIVES BY REPLACING PYRAZOLIC ACIDS WITH ANTHRANIC ACID ESTERS
|
JP6018197B2
(ja)
|
2011-07-21 |
2016-11-02 |
クローダ インターナショナル パブリック リミティド カンパニー |
分枝状ポリエーテル−ポリアミドブロックコポリマー並びにそれらの製造方法及び使用方法
|
JP2014521687A
(ja)
|
2011-07-29 |
2014-08-28 |
セレクタ バイオサイエンシーズ インコーポレーテッド |
体液性および細胞傷害性tリンパ球(ctl)免疫応答を生成する合成ナノキャリア
|
KR20140051357A
(ko)
|
2011-08-26 |
2014-04-30 |
애로우헤드 리서치 코오포레이션 |
In Vivo 핵산 전달용 폴리(비닐 에스테르) 고분자
|
EP2750712A2
(en)
|
2011-08-31 |
2014-07-09 |
Mallinckrodt LLC |
Nanoparticle peg modification with h-phosphonates
|
US9126966B2
(en)
|
2011-08-31 |
2015-09-08 |
Protiva Biotherapeutics, Inc. |
Cationic lipids and methods of use thereof
|
EP2755986A4
(en)
|
2011-09-12 |
2015-05-20 |
Moderna Therapeutics Inc |
MODIFIED NUCLEIC ACIDS AND METHODS OF USE
|
JP2014531456A
(ja)
|
2011-09-22 |
2014-11-27 |
バインド セラピューティックス インコーポレイテッド |
治療用ナノ粒子と癌を治療する方法
|
WO2013072929A2
(en)
|
2011-09-23 |
2013-05-23 |
Indian Institute Of Technology |
Nanop article based cosmetic composition
|
ES2911677T3
(es)
|
2011-10-03 |
2022-05-20 |
Modernatx Inc |
Nucleósidos, nucleótidos y ácidos nucleicos modificados, y sus usos
|
EP2765997A4
(en)
|
2011-10-14 |
2015-06-24 |
Stc Unm |
POROUS NANOPARTICLE-SUPPORTED LIPIDIC BILCHES (PROTOCELLS) FOR TARGETED DELIVERY, COMPRISING TRANSDERMAL DELIVERY OF CARGO MOLECULE, AND ASSOCIATED METHODS
|
EP3960726A1
(en)
|
2011-10-18 |
2022-03-02 |
Dicerna Pharmaceuticals, Inc. |
Amine cationic lipids and uses thereof
|
EP3915545A1
(en)
|
2011-10-25 |
2021-12-01 |
The University of British Columbia |
Limit size lipid nanoparticles and related methods
|
JP6151707B2
(ja)
|
2011-10-27 |
2017-06-21 |
マサチューセッツ インスティテュート オブ テクノロジー |
薬物内包微小球の形成が可能なn−末端で官能基化されたアミノ酸誘導体
|
SG11201401851UA
(en)
|
2011-10-28 |
2014-05-29 |
Presage Biosciences Inc |
Methods for drug delivery
|
LT2773326T
(lt)
|
2011-11-04 |
2019-04-25 |
Nitto Denko Corporation |
Lipidų-nukleorūgščių dalelių sterilios gamybos būdas
|
SG10202103003RA
(en)
|
2011-11-18 |
2021-05-28 |
Regeneron Pharma |
Polymer protein microparticles
|
CA2856895C
(en)
|
2011-11-28 |
2021-10-26 |
Merck Patent Gmbh |
Anti-pd-l1 antibodies and uses thereof
|
WO2013082111A2
(en)
|
2011-11-29 |
2013-06-06 |
The University Of North Carolina At Chapel Hill |
Geometrically engineered particles and methods for modulating macrophage or immune responses
|
EP3988537A1
(en)
|
2011-12-07 |
2022-04-27 |
Alnylam Pharmaceuticals, Inc. |
Biodegradable lipids for the delivery of active agents
|
WO2013086373A1
(en)
|
2011-12-07 |
2013-06-13 |
Alnylam Pharmaceuticals, Inc. |
Lipids for the delivery of active agents
|
GB201121070D0
(en)
|
2011-12-07 |
2012-01-18 |
Isis Innovation |
composition for delivery of biotherapeutics
|
WO2013086526A1
(en)
|
2011-12-09 |
2013-06-13 |
The Regents Of The University Of California |
Liposomal drug encapsulation
|
SG10201601349XA
(en)
|
2011-12-13 |
2016-03-30 |
Engeneic Molecular Delivery Pty Ltd |
Bacterially derived, intact minicells for delivery of therapeutic agents to brain tumors
|
RS63244B1
(sr)
|
2011-12-16 |
2022-06-30 |
Modernatx Inc |
Kompozicije modifikovane mrna
|
WO2013090601A2
(en)
|
2011-12-16 |
2013-06-20 |
Massachusetts Institute Of Technology |
Compact nanoparticles for biological applications
|
WO2013105101A1
(en)
|
2012-01-13 |
2013-07-18 |
Department Of Biotechnology |
Solid lipid nanoparticles entrapping hydrophilic/ amphiphilic drug and a process for preparing the same
|
EP2804632B1
(en)
|
2012-01-19 |
2019-09-18 |
The Johns Hopkins University |
Nanoparticle formulations with enhanced mucosal penetration
|
WO2013116126A1
(en)
|
2012-02-01 |
2013-08-08 |
Merck Sharp & Dohme Corp. |
Novel low molecular weight, biodegradable cationic lipids for oligonucleotide delivery
|
CA3069030C
(en)
|
2012-02-03 |
2021-11-16 |
Rutgers, The State University Of New Jersey |
Polymeric biomaterials derived from phenolic monomers and their medical uses
|
US9737480B2
(en)
|
2012-02-06 |
2017-08-22 |
President And Fellows Of Harvard College |
ARRDC1-mediated microvesicles (ARMMs) and uses thereof
|
JP6170074B2
(ja)
|
2012-02-09 |
2017-07-26 |
ライフ テクノロジーズ コーポレーション |
親水性ポリマー粒子およびその製造方法
|
EP2812383A1
(en)
|
2012-02-10 |
2014-12-17 |
E. I. Du Pont de Nemours and Company |
Preparation, purification and use of high-x diblock copolymers
|
CN104394853B
(zh)
|
2012-02-19 |
2017-10-10 |
纳维基因股份有限公司 |
多孔性纳米结构在递送中的用途
|
SG11201405157PA
(en)
|
2012-02-24 |
2014-10-30 |
Protiva Biotherapeutics Inc |
Trialkyl cationic lipids and methods of use thereof
|
US20140010861A1
(en)
|
2012-04-02 |
2014-01-09 |
modeRNA Therapeutics |
Modified polynucleotides for the production of proteins associated with human disease
|
CA2868391A1
(en)
|
2012-04-02 |
2013-10-10 |
Stephane Bancel |
Polynucleotides comprising n1-methyl-pseudouridine and methods for preparing the same
|
CN104470949A
(zh)
|
2012-05-15 |
2015-03-25 |
百时美施贵宝公司 |
通过破坏pd-1/pd-l1信号传输的免疫治疗
|
EP2885419A4
(en)
|
2012-08-14 |
2016-05-25 |
Moderna Therapeutics Inc |
ENZYMES AND POLYMERASES FOR RNA SYNTHESIS
|
US20150307542A1
(en)
|
2012-10-03 |
2015-10-29 |
Moderna Therapeutics, Inc. |
Modified nucleic acid molecules and uses thereof
|
AU2013374345A1
(en)
|
2013-01-17 |
2015-08-06 |
Moderna Therapeutics, Inc. |
Signal-sensor polynucleotides for the alteration of cellular phenotypes
|
EP2964234A4
(en)
|
2013-03-09 |
2016-12-07 |
Moderna Therapeutics Inc |
NON-TRANSLATED HETEROLOGOUS REGIONS FOR MRNA
|
WO2015007871A2
(en)
*
|
2013-07-17 |
2015-01-22 |
Ospedale San Raffaele S.R.L. |
Micrornas and autoimmune-immune mediated inflammatory disease
|
PT3702373T
(pt)
|
2013-09-13 |
2022-09-27 |
Beigene Switzerland Gmbh |
Anticorpos anti-pd1 e a sua utilização como agentes terapêuticos e de diagnóstico
|
US10023626B2
(en)
*
|
2013-09-30 |
2018-07-17 |
Modernatx, Inc. |
Polynucleotides encoding immune modulating polypeptides
|
ES2746340T3
(es)
|
2015-04-22 |
2020-03-05 |
Curevac Ag |
Composición que contiene ARN para el tratamiento de enfermedades tumorales
|
HRP20220525T1
(hr)
|
2015-12-23 |
2022-05-27 |
Modernatx, Inc. |
Postupci uporabe polinukleotida koji kodiraju ligand ox40
|
EP3452101A2
(en)
|
2016-05-04 |
2019-03-13 |
CureVac AG |
Rna encoding a therapeutic protein
|
JP7194594B2
(ja)
*
|
2016-05-18 |
2022-12-22 |
モデルナティエックス インコーポレイテッド |
免疫調節ポリペプチドをコードするmRNAの組み合わせ及びその使用
|
MA45037A
(fr)
|
2016-05-18 |
2019-03-27 |
Modernatx Inc |
Polythérapie à base d'arnm pour le traitement du cancer
|