CA2868996A1 - Modified polynucleotides for the production of proteins - Google Patents

Modified polynucleotides for the production of proteins Download PDF

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Publication number
CA2868996A1
CA2868996A1 CA2868996A CA2868996A CA2868996A1 CA 2868996 A1 CA2868996 A1 CA 2868996A1 CA 2868996 A CA2868996 A CA 2868996A CA 2868996 A CA2868996 A CA 2868996A CA 2868996 A1 CA2868996 A1 CA 2868996A1
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CA
Canada
Prior art keywords
optionally substituted
independently
polypeptide
polynucleotide
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2868996A
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English (en)
French (fr)
Inventor
Stephane Bancel
Tirtha Chakraborty
Antonin De Fougerolles
Sayda M. ELBASHIR
Matthias John
Atanu Roy
Susan Whoriskey
Kristy M. WOOD
Paul Hatala
Jason P. SCHRUM
Kenechi Ejebe
Jeff Lynn Ellsworth
Justin Guild
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Moderna Inc
Original Assignee
Moderna Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49235350&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2868996(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Moderna Therapeutics Inc filed Critical Moderna Therapeutics Inc
Publication of CA2868996A1 publication Critical patent/CA2868996A1/en
Abandoned legal-status Critical Current

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    • A61K48/0066—Manipulation of the nucleic acid to modify its expression pattern, e.g. enhance its duration of expression, achieved by the presence of particular introns in the delivered nucleic acid
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CA2868996A 2012-04-02 2013-03-09 Modified polynucleotides for the production of proteins Abandoned CA2868996A1 (en)

Applications Claiming Priority (103)

Application Number Priority Date Filing Date Title
US201261618870P 2012-04-02 2012-04-02
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US201261648286P 2012-05-17 2012-05-17
US201261648244P 2012-05-17 2012-05-17
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US201261668157P 2012-07-05 2012-07-05
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US201261681648P 2012-08-10 2012-08-10
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