DK0460171T3 - CD3-specifikt rekombinant antistof - Google Patents

CD3-specifikt rekombinant antistof

Info

Publication number
DK0460171T3
DK0460171T3 DK91901559.4T DK91901559T DK0460171T3 DK 0460171 T3 DK0460171 T3 DK 0460171T3 DK 91901559 T DK91901559 T DK 91901559T DK 0460171 T3 DK0460171 T3 DK 0460171T3
Authority
DK
Denmark
Prior art keywords
antibody
pref
derived
chain
cdr
Prior art date
Application number
DK91901559.4T
Other languages
Danish (da)
English (en)
Inventor
John Robert Adair
Linda Kay Jolliffe
Robert Allan Zivin
Diljeet Singh Athwal
Original Assignee
Celltech Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10668300&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0460171(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Celltech Therapeutics Ltd filed Critical Celltech Therapeutics Ltd
Application granted granted Critical
Publication of DK0460171T3 publication Critical patent/DK0460171T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2812—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/461—Igs containing Ig-regions, -domains or -residues form different species
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/461—Igs containing Ig-regions, -domains or -residues form different species
    • C07K16/464—Igs containing CDR-residues from one specie grafted between FR-residues from another
    • C07K16/465—Igs containing CDR-residues from one specie grafted between FR-residues from another with additional modified FR-residues
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
DK91901559.4T 1989-12-21 1990-12-21 CD3-specifikt rekombinant antistof DK0460171T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898928874A GB8928874D0 (en) 1989-12-21 1989-12-21 Humanised antibodies

Publications (1)

Publication Number Publication Date
DK0460171T3 true DK0460171T3 (da) 1995-08-28

Family

ID=10668300

Family Applications (4)

Application Number Title Priority Date Filing Date
DK91901559.4T DK0460171T3 (da) 1989-12-21 1990-12-21 CD3-specifikt rekombinant antistof
DK94202090T DK0626390T3 (da) 1989-12-21 1990-12-21 Humaniserede antistoffer
DK91901433.2T DK0460167T3 (da) 1989-12-21 1990-12-21 Humaniserede antistoffer
DK91901835.8T DK0460178T3 (da) 1989-12-21 1990-12-21 CD4-specifikt rekombinant antistof

Family Applications After (3)

Application Number Title Priority Date Filing Date
DK94202090T DK0626390T3 (da) 1989-12-21 1990-12-21 Humaniserede antistoffer
DK91901433.2T DK0460167T3 (da) 1989-12-21 1990-12-21 Humaniserede antistoffer
DK91901835.8T DK0460178T3 (da) 1989-12-21 1990-12-21 CD4-specifikt rekombinant antistof

Country Status (21)

Country Link
US (10) US5929212A (no)
EP (5) EP0460167B1 (no)
JP (4) JP3452062B2 (no)
KR (3) KR100197956B1 (no)
AT (4) ATE159299T1 (no)
AU (4) AU649645B2 (no)
BG (1) BG60462B1 (no)
BR (1) BR9007197A (no)
CA (3) CA2050479C (no)
DE (4) DE69020544T2 (no)
DK (4) DK0460171T3 (no)
ES (4) ES2112270T3 (no)
FI (4) FI108917B (no)
GB (4) GB8928874D0 (no)
GR (2) GR3017734T3 (no)
HU (4) HUT60786A (no)
NO (5) NO316076B1 (no)
RO (3) RO114232B1 (no)
RU (1) RU2112037C1 (no)
WO (3) WO1991009966A1 (no)
ZA (1) ZA9110129B (no)

Families Citing this family (1294)

* Cited by examiner, † Cited by third party
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RU2112037C1 (ru) 1998-05-27
GB2268744A (en) 1994-01-19
AU7048691A (en) 1991-07-24
FI109768B (fi) 2002-10-15
US20060029593A1 (en) 2006-02-09
GB2246570B (en) 1994-05-11
EP0460178A1 (en) 1991-12-11
EP0460167B1 (en) 1995-10-11
EP0460167A1 (en) 1991-12-11
DE69033857T2 (de) 2002-09-12
KR100197956B1 (ko) 1999-06-15
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HU912751D0 (en) 1992-01-28
NO913228L (no) 1991-10-21
ATE124459T1 (de) 1995-07-15
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ES2165864T3 (es) 2002-04-01
NO913271L (no) 1991-08-20
US7241877B2 (en) 2007-07-10
US20050136054A1 (en) 2005-06-23
DK0460178T3 (da) 1997-12-22
ATE208794T1 (de) 2001-11-15
US20060073137A1 (en) 2006-04-06
ATE129017T1 (de) 1995-10-15
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