DE60238497D1 - Immunglobulin mit einem bestimmten rahmengerüst und verfahren zu dessen herstellung und verwendung - Google Patents
Immunglobulin mit einem bestimmten rahmengerüst und verfahren zu dessen herstellung und verwendungInfo
- Publication number
- DE60238497D1 DE60238497D1 DE60238497T DE60238497T DE60238497D1 DE 60238497 D1 DE60238497 D1 DE 60238497D1 DE 60238497 T DE60238497 T DE 60238497T DE 60238497 T DE60238497 T DE 60238497T DE 60238497 D1 DE60238497 D1 DE 60238497D1
- Authority
- DE
- Germany
- Prior art keywords
- immunoglobulin
- production
- particular frame
- frame scaffold
- scaffold
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/081—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/13—Immunoglobulins specific features characterized by their source of isolation or production isolated from plants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/23—Immunoglobulins specific features characterized by taxonomic origin from birds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/567—Framework region [FR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Virology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US31890401P | 2001-09-14 | 2001-09-14 | |
PCT/US2002/029003 WO2003025124A2 (en) | 2001-09-14 | 2002-09-13 | Immunoglobulin having particular framework scaffold and methods of making and using |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60238497D1 true DE60238497D1 (de) | 2011-01-13 |
Family
ID=23240056
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60238497T Expired - Lifetime DE60238497D1 (de) | 2001-09-14 | 2002-09-13 | Immunglobulin mit einem bestimmten rahmengerüst und verfahren zu dessen herstellung und verwendung |
Country Status (5)
Country | Link |
---|---|
US (1) | US20050037420A1 (de) |
EP (1) | EP1434800B1 (de) |
AU (1) | AU2002324973A1 (de) |
DE (1) | DE60238497D1 (de) |
WO (1) | WO2003025124A2 (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2002359913A1 (en) * | 2001-12-20 | 2003-07-09 | Agricultural Research Council | Semi-synthetic antibody fragment combinatorial library based on avian immunoglobulin genes |
KR20060069825A (ko) * | 2003-08-01 | 2006-06-22 | 제넨테크, 인크. | 제한된 다양성을 갖는 항체 cdr 폴리펩티드 서열 |
US7785903B2 (en) | 2004-04-09 | 2010-08-31 | Genentech, Inc. | Variable domain library and uses |
US20090028854A1 (en) * | 2005-06-10 | 2009-01-29 | Chugai Seiyaku Kabushiki Kaisha | sc(Fv)2 SITE-DIRECTED MUTANT |
WO2007056441A2 (en) | 2005-11-07 | 2007-05-18 | Genentech, Inc. | Binding polypeptides with diversified and consensus vh/vl hypervariable sequences |
WO2007064919A2 (en) * | 2005-12-02 | 2007-06-07 | Genentech, Inc. | Binding polypeptides with restricted diversity sequences |
AU2007249408A1 (en) * | 2006-05-09 | 2007-11-22 | Genentech, Inc. | Binding polypeptides with optimized scaffolds |
GB2461546B (en) * | 2008-07-02 | 2010-07-07 | Argen X Bv | Antigen binding polypeptides |
PT3354657T (pt) | 2009-09-22 | 2022-05-06 | Medicago Inc | Método de preparação de proteínas derivadas de plantas |
TWI620816B (zh) | 2011-03-23 | 2018-04-11 | 苜蓿股份有限公司 | 植物衍生蛋白回收方法 |
WO2014016737A1 (en) * | 2012-07-24 | 2014-01-30 | Pfizer Inc. | Novel chicken monoclonal antibodies against human phosphorylated tau and uses thereof |
KR20160023725A (ko) * | 2013-07-03 | 2016-03-03 | 서울대학교산학협력단 | 시스테인으로 변형된 닭의 항체 및 이를 이용한 부위-특이적 접합 |
AU2021232512A1 (en) * | 2020-03-02 | 2022-09-29 | The Regents Of The University Of California | Chimeric antigen receptors and related methods and compositions for the treatment of cancer |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8928874D0 (en) * | 1989-12-21 | 1990-02-28 | Celltech Ltd | Humanised antibodies |
AU717611B2 (en) * | 1994-10-28 | 2000-03-30 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Tumor-specific antibody fragments, fusion proteins, and uses thereof |
CN1354671A (zh) * | 1998-11-02 | 2002-06-19 | 加利福尼亚大学董事会 | 抑制受磷蛋白活性以治疗心脏病和心力衰竭的方法 |
EP1479694B1 (de) * | 1999-12-28 | 2016-10-26 | ESBATech, an Alcon Biomedical Research Unit LLC | ScFv Intrakörper mit definierter Struktur ("Framework"), der in einer reduzierenden Umgebung stabil ist |
IT1307309B1 (it) * | 1999-12-30 | 2001-10-30 | Enea Ente Nuove Tec | Peptidi stabilizzanti, polipeptidi ed anticorpi che li comprendono. |
WO2003089475A2 (en) * | 2002-04-22 | 2003-10-30 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Antibodies, recombinant antibodies, recombinant antibody fragments and fusions mediated plant disease resistance against fungi |
-
2002
- 2002-09-13 WO PCT/US2002/029003 patent/WO2003025124A2/en not_active Application Discontinuation
- 2002-09-13 AU AU2002324973A patent/AU2002324973A1/en not_active Abandoned
- 2002-09-13 DE DE60238497T patent/DE60238497D1/de not_active Expired - Lifetime
- 2002-09-13 US US10/489,328 patent/US20050037420A1/en not_active Abandoned
- 2002-09-13 EP EP02759649A patent/EP1434800B1/de not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
WO2003025124A2 (en) | 2003-03-27 |
EP1434800B1 (de) | 2010-12-01 |
US20050037420A1 (en) | 2005-02-17 |
EP1434800A2 (de) | 2004-07-07 |
WO2003025124A3 (en) | 2003-09-18 |
AU2002324973A1 (en) | 2003-04-01 |
EP1434800A4 (de) | 2006-05-10 |
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