ATE388947T1 - Escitalopramhydrobromid und ein verfahren zu dessen herstellung - Google Patents

Escitalopramhydrobromid und ein verfahren zu dessen herstellung

Info

Publication number
ATE388947T1
ATE388947T1 AT03779759T AT03779759T ATE388947T1 AT E388947 T1 ATE388947 T1 AT E388947T1 AT 03779759 T AT03779759 T AT 03779759T AT 03779759 T AT03779759 T AT 03779759T AT E388947 T1 ATE388947 T1 AT E388947T1
Authority
AT
Austria
Prior art keywords
production
escitalopram hydrobromide
escitalopram
hydrobromide
Prior art date
Application number
AT03779759T
Other languages
English (en)
Inventor
Lawrence Martel
Robert Dancer
Hans Petersen
Peter Ellegaard
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32668635&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE388947(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Application granted granted Critical
Publication of ATE388947T1 publication Critical patent/ATE388947T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Addiction (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Nutrition Science (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
AT03779759T 2002-12-23 2003-12-18 Escitalopramhydrobromid und ein verfahren zu dessen herstellung ATE388947T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA200202005 2002-12-23

Publications (1)

Publication Number Publication Date
ATE388947T1 true ATE388947T1 (de) 2008-03-15

Family

ID=32668635

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03779759T ATE388947T1 (de) 2002-12-23 2003-12-18 Escitalopramhydrobromid und ein verfahren zu dessen herstellung

Country Status (32)

Country Link
US (1) US20040167209A1 (de)
EP (1) EP1578738B1 (de)
JP (2) JP4658613B2 (de)
KR (1) KR20050086933A (de)
CN (1) CN100349885C (de)
AR (1) AR042652A1 (de)
AT (1) ATE388947T1 (de)
AU (1) AU2003287919B2 (de)
BR (1) BR0317623A (de)
CA (1) CA2511142A1 (de)
CY (1) CY1107451T1 (de)
DE (1) DE60319739T2 (de)
DK (1) DK1578738T3 (de)
EA (1) EA013116B1 (de)
EG (1) EG24729A (de)
ES (1) ES2298595T3 (de)
IL (1) IL169125A0 (de)
IS (1) IS2654B (de)
ME (1) MEP5808A (de)
MX (1) MXPA05005772A (de)
MY (1) MY135468A (de)
NO (1) NO20053595L (de)
NZ (1) NZ540281A (de)
PE (1) PE20040924A1 (de)
PL (1) PL378275A1 (de)
PT (1) PT1578738E (de)
RS (1) RS51092B (de)
TW (1) TW200501943A (de)
UA (1) UA80170C2 (de)
UY (1) UY28148A1 (de)
WO (1) WO2004056791A1 (de)
ZA (1) ZA200504109B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050137255A1 (en) * 2002-12-23 2005-06-23 H. Lundbeck A/S Crystalline escitalopram hydrobromide and methods for preparing the same
MEP5808A (xx) * 2002-12-23 2010-02-10 Lundbeck & Co As H Ecitalopram bromhidrat i postupak za njegovo pripremanje
NZ549100A (en) * 2004-03-05 2010-02-26 Lundbeck & Co As H Crystalline composition containing escitalopram oxalate
US7834201B2 (en) 2005-06-22 2010-11-16 H. Lundbeck A/S Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base
TWI358407B (en) 2005-06-22 2012-02-21 Lundbeck & Co As H Crystalline base of escitalopram and orodispersibl
EA200801080A1 (ru) * 2005-10-14 2009-02-27 Х. Лундбекк А/С Стабильные фармацевтические лекарственные формы, содержащие эсциталопрам и бупропион
CA2625835A1 (en) * 2005-10-14 2007-05-10 Forest Laboratories, Inc. Methods of treating central nervous system disorders with a low dose combination of escitalopram and bupropion
TW200812993A (en) * 2006-05-02 2008-03-16 Lundbeck & Co As H New uses of escitalopram
US8030303B2 (en) 2006-07-11 2011-10-04 Mitsubishi Tanabe Pharma Corporation Salt of morpholine compound
WO2008059514A2 (en) * 2006-07-31 2008-05-22 Cadila Healthcare Limited Process for preparing escitalopram
FR3006594A1 (fr) * 2013-06-11 2014-12-12 Sorin Crm Sas Microsonde implantable de detection/stimulation incorporant un agent anti-inflammatoire
CN108976188B (zh) * 2017-06-05 2022-12-06 上海奥博生物医药股份有限公司 一种艾司西酞普兰双羟萘酸盐新的制备方法
US11390597B2 (en) * 2017-10-09 2022-07-19 Mark Hasleton Salt and solid state forms of escitalopram
EP4277661A1 (de) 2021-01-18 2023-11-22 Anton Frenkel Pharmazeutische darreichungsform

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US34712A (en) * 1862-03-18 James h
GB1526331A (en) * 1976-01-14 1978-09-27 Kefalas As Phthalanes
GB8419963D0 (en) * 1984-08-06 1984-09-12 Lundbeck & Co As H Intermediate compound and method
GB8814057D0 (en) * 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
ES2189502T3 (es) * 1998-10-20 2003-07-01 Lundbeck & Co As H Metodo para la prevencion de citalopram.
AR021155A1 (es) * 1999-07-08 2002-06-12 Lundbeck & Co As H Tratamiento de desordenes neuroticos
DK1298124T3 (da) * 1999-10-25 2007-07-09 Lundbeck & Co As H Fremgangsmåde til fremstilling af citalopram
US6977306B2 (en) * 2000-05-02 2005-12-20 Sumitomo Chemical Company, Limited Citalopram hydrobromide crystal and method for crystallization thereof
JP2002020379A (ja) * 2000-05-02 2002-01-23 Sumika Fine Chemicals Co Ltd シタロプラム臭化水素酸塩の結晶およびその結晶化方法
CA2353693C (en) * 2000-08-10 2003-07-22 H. Lundbeck A/S Pharmaceutical composition containing citalopram
ES2289016T3 (es) * 2000-12-04 2008-02-01 Westfalia Separator Ag Procedimiento para la obtencion de esteres de acidos grasos.
CZ20033267A3 (en) * 2001-05-01 2004-06-16 H. Lundbeck A/S The use of enantiomeric pure escitalopram
AR034612A1 (es) * 2001-06-25 2004-03-03 Lundbeck & Co As H Proceso para la preparacion del citalopram racemico y/o del s- o r-citalopram mediante la separacion de una mezcla de r- y s-citalopram
MEP5808A (xx) * 2002-12-23 2010-02-10 Lundbeck & Co As H Ecitalopram bromhidrat i postupak za njegovo pripremanje
US20050174782A1 (en) * 2003-03-25 2005-08-11 Chapman Leonard T. Flashlight

Also Published As

Publication number Publication date
EG24729A (en) 2010-06-21
IS2654B (is) 2010-08-15
IL169125A0 (en) 2009-02-11
RS51092B (sr) 2010-10-31
ES2298595T3 (es) 2008-05-16
EP1578738A1 (de) 2005-09-28
PL378275A1 (pl) 2006-03-20
JP4658613B2 (ja) 2011-03-23
DE60319739T2 (de) 2008-07-17
AU2003287919A1 (en) 2004-07-14
ZA200504109B (en) 2006-08-30
HK1087708A1 (en) 2006-10-20
BR0317623A (pt) 2005-11-29
CA2511142A1 (en) 2004-07-08
RS20050487A (sr) 2007-06-04
NO20053595L (no) 2005-09-05
IS7848A (is) 2005-05-17
DK1578738T3 (da) 2008-06-30
DE60319739D1 (de) 2008-04-24
EA013116B1 (ru) 2010-02-26
TW200501943A (en) 2005-01-16
MY135468A (en) 2008-04-30
EA200501046A1 (ru) 2005-12-29
US20040167209A1 (en) 2004-08-26
EP1578738B1 (de) 2008-03-12
MXPA05005772A (es) 2005-08-16
UA80170C2 (en) 2007-08-27
UY28148A1 (es) 2004-09-30
NZ540281A (en) 2008-07-31
AR042652A1 (es) 2005-06-29
PE20040924A1 (es) 2004-12-11
MEP5808A (xx) 2010-02-10
AU2003287919B2 (en) 2009-11-12
CN1726202A (zh) 2006-01-25
PT1578738E (pt) 2008-04-11
KR20050086933A (ko) 2005-08-30
JP2011037893A (ja) 2011-02-24
JP2006514952A (ja) 2006-05-18
WO2004056791A1 (en) 2004-07-08
CY1107451T1 (el) 2012-12-19
CN100349885C (zh) 2007-11-21

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