GB1419481A
(en)
|
1973-06-20 |
1975-12-31 |
Ciba Geigy Ag |
Dithiole derivatives useful as additives for lubricating oils and other organic materials
|
CA2241567A1
(en)
|
1996-01-17 |
1997-07-24 |
Novo Nordisk A/S |
Fused 1,2,4-thiadiazine and fused 1,4-thiazine derivatives, their preparation and use
|
DE122010000020I1
(de)
|
1996-04-25 |
2010-07-08 |
Prosidion Ltd |
Verfahren zur Senkung des Blutglukosespiegels in Säugern
|
HU227021B1
(en)
|
1996-08-30 |
2010-05-28 |
Novo Nordisk As |
Glp-1 derivatives
|
HUP0301101A3
(en)
|
1996-12-31 |
2009-03-30 |
Reddy S Res Foundation |
Novel heterocyclic compounds process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
|
DE19726167B4
(de)
|
1997-06-20 |
2008-01-24 |
Sanofi-Aventis Deutschland Gmbh |
Insulin, Verfahren zu seiner Herstellung und es enthaltende pharmazeutische Zubereitung
|
JP2001510195A
(ja)
|
1997-07-16 |
2001-07-31 |
ノボ ノルディスク アクティーゼルスカブ |
縮合化1,2,4−チアジアジン誘導体、その調製及び使用
|
CA2819705C
(en)
|
1998-02-02 |
2014-07-08 |
Trustees Of Tufts College |
Method of regulating glucose metabolism, and reagents related thereto
|
US6903186B1
(en)
|
1998-12-07 |
2005-06-07 |
Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S |
Analogues of GLP-1
|
CZ20013833A3
(cs)
|
1999-04-28 |
2002-02-13 |
Aventis Pharma Deutschland Gmbh |
Deriváty kyselin se dvěma arylovými zbytky jako ligandy receptorů PPAR a farmaceutické prostředky, které je obsahují
|
KR100693771B1
(ko)
|
1999-04-28 |
2007-03-12 |
사노피-아벤티스 도이칠란트 게엠베하 |
Ppar 수용체 리간드로서의 트리아릴 산 유도체 및 이를 포함하는 약제학적 조성물
|
AU769350B2
(en)
|
1999-06-23 |
2004-01-22 |
Sanofi-Aventis Deutschland Gmbh |
Substituted benzimidazole
|
EP1076066A1
(en)
|
1999-07-12 |
2001-02-14 |
Zealand Pharmaceuticals A/S |
Peptides for lowering blood glucose levels
|
AU6985200A
(en)
|
1999-09-10 |
2001-04-17 |
Novo Nordisk A/S |
Modulators of protein tyrosine phosphatases (ptpases)
|
AU7476800A
(en)
|
1999-09-10 |
2001-04-10 |
Novo Nordisk A/S |
Method of inhibiting protein tyrosine phosphatase 1b and/or t-cell protein tyrosine phosphatase and/or other ptpases with an asp residue at position 48
|
DE19951360A1
(de)
|
1999-10-26 |
2001-05-03 |
Aventis Pharma Gmbh |
Substituierte Indole
|
PE20011010A1
(es)
|
1999-12-02 |
2001-10-18 |
Glaxo Group Ltd |
Oxazoles y tiazoles sustituidos como agonista del receptor activado por el proliferador de peroxisomas humano
|
SE0001899D0
(sv)
|
2000-05-22 |
2000-05-22 |
Pharmacia & Upjohn Ab |
New compounds
|
ATE528303T1
(de)
|
2000-12-21 |
2011-10-15 |
Vertex Pharma |
Pyrazoleverbindungen als proteinkinasehemmer
|
TWI311133B
(en)
|
2001-04-20 |
2009-06-21 |
Eisai R&D Man Co Ltd |
Carboxylic acid derivativeand the salt thereof
|
GB0113233D0
(en)
|
2001-05-31 |
2001-07-25 |
Glaxo Group Ltd |
Chemical compounds
|
KR100915108B1
(ko)
|
2001-08-31 |
2009-09-03 |
사노피-아벤티스 도이칠란트 게엠베하 |
Ppar-활성화제로서의 디아릴사이클로알킬 유도체 및 이를 포함하는 약제학적 조성물
|
CA2466490C
(en)
|
2001-11-22 |
2009-12-29 |
Biovitrum Ab |
Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1
|
CA2466491A1
(en)
|
2001-11-22 |
2003-05-30 |
Biovitrum Ab |
Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1
|
KR20050044517A
(ko)
|
2001-11-22 |
2005-05-12 |
바이오비트럼 에이비 |
11-베타-히드록시 스테로이드 탈수소효소 유형 1 의억제제
|
JP4368683B2
(ja)
|
2002-02-01 |
2009-11-18 |
メルク エンド カムパニー インコーポレーテッド |
糖尿病、肥満症および脂質代謝異常の治療に有用な11−ベータ−ヒドロキシステロイドデヒドロゲナーゼ1阻害剤
|
ATE346070T1
(de)
|
2002-03-05 |
2006-12-15 |
Lilly Co Eli |
Purinderivate als kinaseinhibitoren
|
HUP0200849A2
(hu)
|
2002-03-06 |
2004-08-30 |
Sanofi-Synthelabo |
N-aminoacetil-2-ciano-pirrolidin-származékok, e vegyületeket tartalmazó gyógyszerkészítmények és eljárás előállításukra
|
FR2836915B1
(fr)
|
2002-03-11 |
2008-01-11 |
Aventis Pharma Sa |
Derives d'aminoindazoles, procede de preparation et intermediaires de ce procede a titre de medicaments et compositions pharmaceutiques les renfermant
|
DE10215907A1
(de)
|
2002-04-11 |
2003-11-06 |
Aventis Pharma Gmbh |
Acyl-4-carboxyphenyl-harnstoffderivate, Verfahren zu deren Herstellung und deren Verwendung
|
WO2003097064A1
(fr)
|
2002-05-17 |
2003-11-27 |
Kyowa Hakko Kogyo Co., Ltd. |
Agent de traitement du diabète
|
AR040241A1
(es)
|
2002-06-10 |
2005-03-23 |
Merck & Co Inc |
Inhibidores de la 11-beta-hidroxiesteroide deshidrogrenasa 1 para el tratamiento de la diabetes obesidad y dislipidemia
|
DE10226462A1
(de)
|
2002-06-13 |
2003-12-24 |
Aventis Pharma Gmbh |
Fluorierte Cycloalkyl-derivatisierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament, sowie sie enthaltendes Medikament
|
HUP0202001A2
(hu)
|
2002-06-14 |
2005-08-29 |
Sanofi-Aventis |
DDP-IV gátló hatású azabiciklooktán- és nonánszármazékok
|
DE10231370B4
(de)
|
2002-07-11 |
2006-04-06 |
Sanofi-Aventis Deutschland Gmbh |
Thiophenglycosidderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zur Herstellung dieser Arzneimittel
|
PL373329A1
(en)
|
2002-07-12 |
2005-08-22 |
Sanofi-Aventis Deutschland Gmbh |
Heterocyclically substituted benzoylureas, method for their production and their use as medicaments
|
WO2004011410A1
(en)
|
2002-07-27 |
2004-02-05 |
Astrazeneca Ab |
Chemical compounds
|
BR0313262A
(pt)
|
2002-08-07 |
2005-07-12 |
Mitsubishi Pharma Corp |
Compostos de dihidropirazolpiridina
|
DE10237723A1
(de)
|
2002-08-17 |
2004-07-08 |
Aventis Pharma Deutschland Gmbh |
Verwendung von IKappaB-Kinase Inhibitoren in der Schmerztherapie
|
DE10237722A1
(de)
|
2002-08-17 |
2004-08-19 |
Aventis Pharma Deutschland Gmbh |
Indol- oder Benzimidazolderivate zur Modulation der IKappaB-Kinase
|
EP1537087B1
(fr)
|
2002-09-05 |
2012-11-28 |
Aventis Pharma S.A. |
Derives de 3-aminoindazole comme inhibiteurs de kinase et compositions pharmaceutiques les renfermant
|
ATE345340T1
(de)
|
2002-09-12 |
2006-12-15 |
Hoffmann La Roche |
N-substituierte-1h-indol-5-propansäure verbindungen als ppar-agonisten zur behandlung von diabetis
|
JP2006506451A
(ja)
|
2002-10-11 |
2006-02-23 |
アストラゼネカ アクチボラグ |
1,4−ジ置換ピペリジン誘導体および11−βHSD1阻害薬としてのそれらの使用
|
KR20050067418A
(ko)
|
2002-10-18 |
2005-07-01 |
머크 앤드 캄파니 인코포레이티드 |
당뇨병을 치료 또는 예방하기 위한 베타-아미노헤테로사이클릭 디펩티딜 펩티다제 억제제
|
MXPA05004434A
(es)
|
2002-10-24 |
2005-07-26 |
Sterix Ltd |
Inhibidores de 11-beta-hidroxi esteroide deshidrogenasa tipo 1 y tipo 2.
|
WO2004041274A1
(en)
|
2002-11-05 |
2004-05-21 |
Arena Pharmaceuticals, Inc. |
Benzotriazoles and methods of prophylaxis or treatment of metabolic-related disorders thereof
|
US20060058315A1
(en)
|
2002-11-07 |
2006-03-16 |
Astrazeneca Ab |
2-Oxo-ethanesulfonamide derivates
|
FR2847253B1
(fr)
|
2002-11-19 |
2007-05-18 |
Aventis Pharma Sa |
Nouveaux derives de pyridazinones a titre de medicaments et compositions pharmaceutiques les renfermant
|
GB0227813D0
(en)
|
2002-11-29 |
2003-01-08 |
Astrazeneca Ab |
Chemical compounds
|
UY28103A1
(es)
|
2002-12-03 |
2004-06-30 |
Boehringer Ingelheim Pharma |
Nuevas imidazo-piridinonas sustituidas, su preparación y su empleo como medicacmentos
|
DE10258007B4
(de)
|
2002-12-12 |
2006-02-09 |
Sanofi-Aventis Deutschland Gmbh |
Aromatische Fluorglycosidderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zur Herstellung dieser Arzneimittel
|
DE10258008B4
(de)
|
2002-12-12 |
2006-02-02 |
Sanofi-Aventis Deutschland Gmbh |
Heterocyclische Fluorglycosidderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zur Herstellung dieser Arzneimittel
|
JO2397B1
(en)
|
2002-12-20 |
2007-06-17 |
ميرك شارب اند دوم كوربوريشن |
Terazol derivatives as beta-hydroxy steroid dihydrogenase-1 inhibitors
|
WO2004056744A1
(en)
|
2002-12-23 |
2004-07-08 |
Janssen Pharmaceutica N.V. |
Adamantyl acetamides as hydroxysteroid dehydrogenase inhibitors
|
WO2004063179A1
(en)
|
2003-01-06 |
2004-07-29 |
Eli Lilly And Company |
Substituted arylcyclopropylacetamides as glucokinase activators
|
NO20030115D0
(no)
|
2003-01-09 |
2003-01-09 |
Amersham Health As |
Kontrastmiddel
|
ES2295816T3
(es)
|
2003-01-14 |
2008-04-16 |
Arena Pharmaceuticals, Inc. |
Derivados arilo y heteroarilo 1,2,3-trisustituidos como moduladores del metabolismo, y profilaxis y tratamiento de transtornos relacionados con los mismos, tales como la diabetes y la hiperglucemia.
|
TW200503994A
(en)
|
2003-01-24 |
2005-02-01 |
Novartis Ag |
Organic compounds
|
WO2004089470A2
(en)
|
2003-04-11 |
2004-10-21 |
Novo Nordisk A/S |
New amide derivatives and pharmaceutical use thereof
|
PL378117A1
(pl)
|
2003-02-11 |
2006-03-06 |
Prosidion Limited |
Tricyklopodstawione związki amidowe
|
EP1594863A1
(en)
|
2003-02-11 |
2005-11-16 |
Prosidion Limited |
Tri(cyclo) substituted amide glucokinase activator compounds
|
CN100361992C
(zh)
|
2003-02-19 |
2008-01-16 |
霍夫曼-拉罗奇有限公司 |
用作pepck抑制剂的磺酰胺取代的黄嘌呤
|
EP1460075A1
(en)
|
2003-03-21 |
2004-09-22 |
Sanofi-Synthelabo |
Substituted 8-Pyridinyl-6,7,8,9-Tetrahydropyrimido[1,2-a]Pyrimidin-4-one and 8-Phenyl-6-7,8,9-Tetrahydropyrimido[1,2-a]Pyrimidin-4-one derivatives
|
EP1615637A1
(en)
|
2003-04-11 |
2006-01-18 |
Novo Nordisk A/S |
Pharmaceutical use of substituted 1,2,4-triazoles
|
WO2004089380A2
(en)
|
2003-04-11 |
2004-10-21 |
Novo Nordisk A/S |
Pharmaceutical use of fused 1,2,4-triazoles
|
EP1626717A4
(en)
|
2003-05-09 |
2009-09-09 |
Merck & Co Inc |
BENZIMIDAZOLE, COMPOSITIONS AND METHOD OF ADMINISTRATION CONTAINING SUCH COMPOUNDS
|
US7067529B2
(en)
|
2003-05-19 |
2006-06-27 |
Hoffmann-La Roche Inc. |
Glutamine fructose-y-phosphate amidotransferase (GFAT) inhibitors
|
CA2525945A1
(en)
|
2003-05-21 |
2004-12-02 |
Biovitrum Ab |
Inhibitors of 11-beta-hydroxy steroid dehydrogenase type i
|
JP4499106B2
(ja)
|
2003-05-29 |
2010-07-07 |
メルク・シャープ・エンド・ドーム・コーポレイション |
11−ベータ−水酸化ステロイド脱水素酵素−1の阻害剤としてのトリアゾール誘導体
|
WO2004106343A2
(en)
|
2003-05-30 |
2004-12-09 |
Ufc Limited |
Agelastatin derivatives of antitumour and gsk-3beta-inhibiting alkaloids
|
JP2004359630A
(ja)
|
2003-06-06 |
2004-12-24 |
Yamanouchi Pharmaceut Co Ltd |
ジフルオロジフェニルメタン誘導体及びその塩
|
DE602004016174D1
(de)
|
2003-06-13 |
2008-10-09 |
Janssen Pharmaceutica Nv |
Substituierte indazolyl(indolyl)maleimid-derivate als kinase inhibitoren
|
SE0301888D0
(sv)
|
2003-06-25 |
2003-06-25 |
Biovitrum Ab |
New use VII
|
SE0301882D0
(sv)
|
2003-06-25 |
2003-06-25 |
Biovitrum Ab |
New use I
|
SE0301886D0
(sv)
|
2003-06-25 |
2003-06-25 |
Biovitrum Ab |
New use V
|
WO2004113310A1
(en)
|
2003-06-25 |
2004-12-29 |
Biovitrum Ab |
Use of an inhibitor of 11-b-hydroxysteroid dehydrogenase type 1 compounds for promoting wound healing
|
EP1644411A2
(en)
|
2003-07-11 |
2006-04-12 |
Novo Nordisk A/S |
Stabilised insulin compositions
|
DE10333935A1
(de)
|
2003-07-25 |
2005-02-24 |
Aventis Pharma Deutschland Gmbh |
Neue bicyclische Cyanoheterocyclen, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
PE20050249A1
(es)
|
2003-07-25 |
2005-06-01 |
Aventis Pharma Gmbh |
Nuevas cianopirrolididas y procedimiento para su preparacion como medicamentos
|
DE10334309A1
(de)
|
2003-07-28 |
2005-03-03 |
Aventis Pharma Deutschland Gmbh |
Substituierte Thiazol-Benzoisothiazoldioxidderivate, Verfahren zu deren Herstellung und deren Verwendung
|
US20050026984A1
(en)
|
2003-07-29 |
2005-02-03 |
Aventis Pharma S.A. |
Substituted thieno [2,3-c] pyrazoles and their use as medicinal products
|
US7008953B2
(en)
|
2003-07-30 |
2006-03-07 |
Agouron Pharmaceuticals, Inc. |
3, 5 Disubstituted indazole compounds, pharmaceutical compositions, and methods for mediating or inhibiting cell proliferation
|
EP1653949A4
(en)
|
2003-08-07 |
2009-04-22 |
Merck & Co Inc |
PYRAZOL CARBOXAMIDE AS AN INHIBITOR OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE-1
|
CA2539253A1
(en)
|
2003-09-19 |
2005-03-31 |
Novo Nordisk A/S |
Albumin-binding derivatives of therapeutic peptides
|
TW200519105A
(en)
|
2003-10-20 |
2005-06-16 |
Lg Life Science Ltd |
Novel inhibitors of DPP-IV, methods of preparing the same, and pharmaceutical compositions containing the same as an active agent
|
GB0325402D0
(en)
|
2003-10-31 |
2003-12-03 |
Astrazeneca Ab |
Compounds
|
CA2547430A1
(en)
|
2003-11-26 |
2005-06-09 |
Takeda Pharmaceutical Company Limited |
Receptor function regulating agent
|
DE10359098A1
(de)
|
2003-12-17 |
2005-07-28 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue 2-(Piperazin-1-yl)- und 2-([1,4]Diazepan-1-yl)-imidazo[4,5-d]pyridazin-4-one, deren Herstellung und deren Verwendung als Arzneimittel
|
EP1557417B1
(en)
|
2003-12-19 |
2007-03-07 |
Sanofi-Aventis |
Substituted 8'-pyri(mi)dinyl-dihydrospiro-[cycloalkylamine]-pyrimido[1,2-a] pyrimidin-6-one derivatives
|
JP2007514794A
(ja)
|
2003-12-19 |
2007-06-07 |
メルク エンド カムパニー インコーポレーテッド |
環式グアニジン、そのような化合物を含む組成、及び使用方法
|
US7365075B2
(en)
|
2003-12-22 |
2008-04-29 |
Amgen Inc. |
Aryl sulfonamide compounds and uses related thereto
|
AU2004303604B2
(en)
|
2003-12-24 |
2011-03-24 |
Prosidion Limited |
Heterocyclic derivatives as GPCR receptor agonists
|
TW200523247A
(en)
|
2003-12-25 |
2005-07-16 |
Takeda Pharmaceutical |
3-(4-benzyloxyphenyl) propanoic acid derivatives
|
EA200601287A1
(ru)
|
2004-01-06 |
2006-10-27 |
Янссен Фармацевтика, Н.В. |
Производные (3-оксо-3,4-дигидрохиноксалин-2-иламино) бензамида и родственные соединения в качестве ингибиторов гликогенфосфорилазы для лечения диабета и ожирения
|
EP1713803B1
(de)
|
2004-01-31 |
2009-08-05 |
Sanofi-Aventis Deutschland GmbH |
7-phenylamino-4-chinolon-3-carbonsäure-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
|
DE102004005172A1
(de)
|
2004-02-02 |
2005-08-18 |
Aventis Pharma Deutschland Gmbh |
Indazolderivate als Inhibitoren der Hormon Sensitiven Lipase
|
EP1718625A1
(en)
|
2004-02-18 |
2006-11-08 |
AstraZeneca AB |
Compounds
|
AU2005220728B2
(en)
*
|
2004-02-27 |
2009-08-06 |
Amgen Inc. |
Compounds, pharmaceutical compositions and methods for use in treating metabolic disorders
|
DE102004010194A1
(de)
|
2004-03-02 |
2005-10-13 |
Aventis Pharma Deutschland Gmbh |
4-Benzimidazol-2-yl-pyridazin-3-on-Derivate, ihre Herstellung und Verwendung in Arzneimitteln
|
CN1934103B
(zh)
|
2004-03-04 |
2011-06-01 |
橘生药品工业株式会社 |
稠杂环衍生物,包含稠杂环衍生物的药物组合物及其医药用途
|
WO2005086904A2
(en)
|
2004-03-08 |
2005-09-22 |
Amgen Inc. |
Therapeutic modulation of ppar (gamma) activity
|
DE102004012068A1
(de)
|
2004-03-12 |
2005-09-29 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue alkyl-haltige 5-Acylindolinone, deren Herstellung und deren Verwendung als Arzneimittel
|
CN1938286A
(zh)
|
2004-03-29 |
2007-03-28 |
默克公司 |
作为11-β-羟甾类脱氢酶-1抑制剂的二芳基三唑
|
JP2007531744A
(ja)
|
2004-04-05 |
2007-11-08 |
武田薬品工業株式会社 |
6−アザインドール化合物
|
EP1586318A1
(en)
|
2004-04-05 |
2005-10-19 |
Neuropharma S.A.U. |
Thiadiazolidinones as GSK-3 inhibitors
|
JP2007532511A
(ja)
|
2004-04-09 |
2007-11-15 |
スミスクライン ビーチャム コーポレーション |
低用量医薬品
|
PE20060269A1
(es)
|
2004-05-12 |
2006-05-11 |
Aventis Pharma Inc |
Acido 2-{[2-(2-metilaminopirimidin-4-il)-1h-indol-5-carbonil]amino}-3-(fenilpiridin-2-ilamino) propionico como inhibidor de la cinasa 1kb
|
EP1604988A1
(en)
|
2004-05-18 |
2005-12-14 |
Sanofi-Aventis Deutschland GmbH |
Pyridazinone derivatives, methods for producing them and their use as pharmaceuticals
|
DE102004026532A1
(de)
|
2004-05-29 |
2006-01-05 |
Sanofi-Aventis Deutschland Gmbh |
Substituierte Oxazol-Benzoisothiazoldioxidderivate, Verfahren zu deren Herstellung und deren Verwendung
|
DE102004028241B4
(de)
|
2004-06-11 |
2007-09-13 |
Sanofi-Aventis Deutschland Gmbh |
Neue Fluorglykosidderivate von Pyrazolen, diese Verbindungen enthaltende Arzneimittel und Herstellung dieser Arzneimittel
|
JP2008504274A
(ja)
|
2004-06-24 |
2008-02-14 |
インサイト・コーポレイション |
アミド化合物およびその医薬としての使用
|
CA2570694A1
(en)
|
2004-06-24 |
2006-02-02 |
Incyte Corporation |
Amido compounds and their use as pharmaceuticals
|
DE102004034697A1
(de)
|
2004-07-17 |
2006-02-09 |
Sanofi-Aventis Deutschland Gmbh |
Mit Diphenylamin oder Diphenylaminderivaten substituierte Salicylthiazole, Verfahren zu deren Herstellung und deren Verwendung
|
JP4690402B2
(ja)
|
2004-07-28 |
2011-06-01 |
エフ.ホフマン−ラ ロシュ アーゲー |
11−β−HSD1インヒビターとしてのアリール−ピリジン誘導体
|
DE102004037554A1
(de)
|
2004-08-03 |
2006-03-16 |
Sanofi-Aventis Deutschland Gmbh |
Substituierte 8-Aminoalkylthio-xanthine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
DE102004038270A1
(de)
|
2004-08-06 |
2006-03-16 |
Sanofi-Aventis Deutschland Gmbh |
Substituierte, bizyklische 8-Amino-xanthine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
DE102004038269A1
(de)
|
2004-08-06 |
2006-03-16 |
Sanofi-Aventis Deutschland Gmbh |
Substituierte, bizyklische 8-Piperidino-xanthine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
ATE472531T1
(de)
|
2004-08-06 |
2010-07-15 |
Merck Sharp & Dohme |
Sulfonylverbindungen als hemmer von 11-beta- hydroxysteroiddehydrogenase-1
|
DE102004038268A1
(de)
|
2004-08-06 |
2006-03-16 |
Sanofi-Aventis Deutschland Gmbh |
Substituierte, bizyklische 8-Pyrrolidino-xanthine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
WO2006018150A1
(de)
|
2004-08-11 |
2006-02-23 |
Boehringer Ingelheim International Gmbh |
D-xylopyranosyl-phenyl-substituierte cyclen, diese verbindungen enthaltende arzneimittel, deren verwendung und verfahren zu ihrer herstellung
|
BRPI0514147A
(pt)
|
2004-08-12 |
2008-05-27 |
Prosidion Ltd |
composto ou um sal farmaceuticamente aceitável do mesmo, composição farmacêutica, métodos de tratamento profilático ou terapêutico de uma condição onde a ativação de gk é desejável, de tratamento profilático ou terapêutico da hiperglicemia ou diabete e de prevenção da diabete em um ser humano que demosntra hiperglicemia pré-diabética ou toleráncia à glicose prejudicada, e, processo para a preparação do composto
|
DE102004039507A1
(de)
|
2004-08-14 |
2006-03-02 |
Sanofi-Aventis Deutschland Gmbh |
Substituierte 8-Aminoalkoxi-xanthine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
BRPI0514372A
(pt)
|
2004-08-18 |
2008-06-10 |
Metabasis Therapeutics Inc |
inibidores de tiazol de frutose 1, 6-bisfosfatase
|
WO2006024627A2
(en)
|
2004-08-30 |
2006-03-09 |
Janssen Pharmaceutica N.V. |
N-2 adamantanyl-2-phenoxy-acetamide derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors
|
KR20070053243A
(ko)
|
2004-09-11 |
2007-05-23 |
사노피-아벤티스 도이칠란트 게엠베하 |
7-아자인돌 및 ppar 작용제로서의 이의 용도
|
EP1803729A4
(en)
|
2004-09-29 |
2008-10-01 |
Kissei Pharmaceutical |
HETEROCYCLIC NITROGENIC COMPOUND 1- (-D-GLYCOPYRANOSYL) -3-SUBSTITUTED, THERAPEUTIC PREPARATION CONTAINING SAID COMPOUND, AND MEDICAL USE OF SAID COMPOUND
|
PT1797042E
(pt)
|
2004-09-29 |
2009-02-12 |
Hoffmann La Roche |
Derivados de indozolona como inibidores de 11b-hsd1
|
EP1796669B1
(en)
|
2004-10-01 |
2010-09-22 |
Merck Sharp & Dohme Corp. |
Aminopiperidines as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
|
JP5107713B2
(ja)
|
2004-10-07 |
2012-12-26 |
ノヴォ ノルディスク アー/エス |
遅延性のエキセンディン−4化合物
|
US7893017B2
(en)
|
2004-10-07 |
2011-02-22 |
Novo Nordisk A/S |
Protracted GLP-1 compounds
|
US8138342B2
(en)
|
2004-10-12 |
2012-03-20 |
High Point Pharmacueticals, LLC |
11β-hydroxysteroid dehydrogenase type 1 active spiro compounds
|
MX2007004882A
(es)
|
2004-10-22 |
2007-05-09 |
Smithkline Beecham Corp |
Derivados de xantina con actividad de receptor de hm74a.
|
WO2006045564A1
(en)
|
2004-10-22 |
2006-05-04 |
Smithkline Beecham Corporation |
Xanthine derivatives with hm74a receptor activity
|
PL1807072T3
(pl)
|
2004-10-29 |
2009-06-30 |
Lilly Co Eli |
Cykloalkilowe pochodne laktamów jako inhibitory 11-ß-HSD1
|
US20090093463A1
(en)
|
2004-11-02 |
2009-04-09 |
Agouron Pharmaceuticals Inc. |
Novel compounds of substituted and unsubtituted adamantyl amides
|
EP1659113A1
(en)
|
2004-11-08 |
2006-05-24 |
Evotec AG |
Inhibitors of 11beta-hydroxy steroid dehydrogenase type 1 (11beta-HSD1)
|
EP1666467A1
(en)
|
2004-11-08 |
2006-06-07 |
Evotec AG |
11Beta-HSD1 Inhibitors
|
WO2006051662A1
(ja)
|
2004-11-09 |
2006-05-18 |
Taisho Pharmaceutical Co., Ltd. |
チアゾール誘導体
|
JP2006160733A
(ja)
|
2004-11-15 |
2006-06-22 |
Taisho Pharmaceut Co Ltd |
シアノフルオロピロリジン誘導体を有効成分として含有する医薬
|
AU2005309606B2
(en)
|
2004-11-29 |
2011-01-06 |
Merck Sharp & Dohme Corp. |
Fused aminopiperidines as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes
|
JPWO2006059744A1
(ja)
|
2004-11-30 |
2008-06-05 |
日本ケミファ株式会社 |
ペルオキシソーム増殖剤活性化受容体δの活性化剤
|
EP1824835A1
(en)
|
2004-12-03 |
2007-08-29 |
Novo Nordisk A/S |
Heteroaromatic glucokinase activators
|
DE102004058449A1
(de)
|
2004-12-03 |
2006-06-14 |
Merck Patent Gmbh |
Tetrahydropyranderivate
|
JP2008007405A
(ja)
|
2004-12-07 |
2008-01-17 |
Takeda Chem Ind Ltd |
カルボキサミド誘導体
|
WO2006065826A2
(en)
|
2004-12-15 |
2006-06-22 |
Merck & Co., Inc. |
Process to chiral beta amino acid derivatives by asymmetric hydrogenation
|
DE102004060542A1
(de)
|
2004-12-16 |
2006-07-06 |
Sanofi-Aventis Deutschland Gmbh |
Hydroxybiphenyl-Carbonsäuren und Derivate, Verfahren zu deren Herstellung und deren Verwendung
|
EP1888544A2
(en)
|
2004-12-17 |
2008-02-20 |
Takeda San Diego, Inc. |
Hydroxysteroid dehydrogenase inhibitors
|
PE20060949A1
(es)
|
2004-12-23 |
2006-10-11 |
Arena Pharm Inc |
Derivados fusionados de pirazol como agonistas del receptor de niacina
|
BRPI0518651A2
(pt)
|
2004-12-24 |
2008-12-02 |
Dainippon Sumitomo Pharma |
composto, uma prà-droga do mesmo, ou um sal do composto ou prà-droga farmaceuticamente aceitÁvel, composiÇço farmacÊutica, inibidor de dipeptidil peptidase iv, uso de um composto, uma prà-droga do mesmo ou um sal do composto ou prà-droga farmaceuticamente aceitÁvel, e, mÉtodo para tratar diabetes
|
JP5065908B2
(ja)
|
2004-12-24 |
2012-11-07 |
プロシディオン・リミテッド |
Gタンパク質結合受容体作動薬
|
JP4980928B2
(ja)
|
2004-12-24 |
2012-07-18 |
プロシディオン・リミテッド |
Gタンパク質共役受容体(gpr116)作動薬および肥満および糖尿病治療のためのその使用
|
US7635699B2
(en)
|
2004-12-29 |
2009-12-22 |
Bristol-Myers Squibb Company |
Azolopyrimidine-based inhibitors of dipeptidyl peptidase IV and methods
|
CA2594098C
(en)
|
2005-01-05 |
2014-04-01 |
Abbott Laboratories |
Inhibitors of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme
|
TW200637839A
(en)
|
2005-01-07 |
2006-11-01 |
Taisho Pharmaceutical Co Ltd |
1-thio-d-glucitol derivatives
|
WO2006073167A1
(ja)
|
2005-01-07 |
2006-07-13 |
Ono Pharmaceutical Co., Ltd. |
ピロリジン誘導体
|
DE102005001053A1
(de)
|
2005-01-07 |
2006-07-20 |
Merck Patent Gmbh |
Quadratsäurederivate
|
MY148521A
(en)
|
2005-01-10 |
2013-04-30 |
Arena Pharm Inc |
Substituted pyridinyl and pyrimidinyl derivatives as modulators of metabolism and the treatment of disorders related thereto
|
DE102005002130A1
(de)
|
2005-01-17 |
2006-07-27 |
Sanofi-Aventis Deutschland Gmbh |
Substituierte N-Aminomethylensulfonamide, ihre Herstellung und Verwendung als Arzneimittel
|
JP5094412B2
(ja)
|
2005-01-19 |
2012-12-12 |
メルク・シャープ・エンド・ドーム・コーポレイション |
糖尿病治療用又は予防用のジペプチジルペプチダーゼ−iv阻害剤としての二環系ピリミジン
|
JP2008100916A
(ja)
|
2005-01-24 |
2008-05-01 |
Dainippon Sumitomo Pharma Co Ltd |
インドール類およびそれを含む医薬組成物
|
AR053329A1
(es)
|
2005-01-31 |
2007-05-02 |
Tanabe Seiyaku Co |
Derivados de indol utiles como inhibidores de los transportadores de glucosa dependientes del sodio (sglt)
|
MX2007009356A
(es)
|
2005-02-03 |
2007-12-07 |
Irm Llc |
Compuestos y composiciones como moduladores de ppar.
|
EP1847531A4
(en)
|
2005-02-09 |
2009-04-22 |
Takeda Pharmaceutical |
PYRAZOLE DERIVATIVE
|
CA2597073C
(en)
|
2005-02-11 |
2014-11-25 |
Eli Lilly And Company |
Glucagon receptor antagonists, preparation and therapeutic uses
|
GB0503053D0
(en)
|
2005-02-14 |
2005-03-23 |
Smithkline Beecham Corp |
Chemical compounds
|
WO2006085112A1
(en)
|
2005-02-14 |
2006-08-17 |
Smithkline Beecham Corporation |
Anthranilic acid derivatives as hm74a receptor agonists
|
GB0503056D0
(en)
|
2005-02-14 |
2005-03-23 |
Smithkline Beecham Corp |
Chemical compounds
|
DE602006019825D1
(de)
|
2005-02-15 |
2011-03-10 |
Kissei Pharmaceutical |
1-substituierte-7-(b-d-glycopyranosyloxy)(aza)indolverbindung und pharmazeutikum, das diese enthält
|
RU2007128987A
(ru)
|
2005-02-15 |
2009-03-27 |
Ново Нордиск А/С (DK) |
3,4-дигидро-1н-изохинолин-2-карбоновой кислоты 5-аминопиридин-2-2-иловые эфиры
|
RU2007135339A
(ru)
|
2005-02-25 |
2009-03-27 |
Такеда Фармасьютикал Компани Лимитед (Jp) |
Производные пиридилуксусной кислоты
|
DE102005012873B4
(de)
|
2005-03-19 |
2007-05-03 |
Sanofi-Aventis Deutschland Gmbh |
Aminocarbonyl substituierte 8-N-Benzimidazole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
DE102005012874A1
(de)
|
2005-03-19 |
2006-09-21 |
Sanofi-Aventis Deutschland Gmbh |
Amid substituierte 8-N-Benzimidazole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
TW200722432A
(en)
|
2005-03-25 |
2007-06-16 |
Sankyo Co |
Thiazole compounds
|
TWI357902B
(en)
|
2005-04-01 |
2012-02-11 |
Lg Life Science Ltd |
Dipeptidyl peptidase-iv inhibiting compounds, meth
|
WO2006106423A2
(en)
|
2005-04-07 |
2006-10-12 |
Pfizer Inc. |
Amino sulfonyl derivatives as inhibitors of human 11-.beta.-hydrosysteroid dehydrogenase
|
US20090054423A1
(en)
|
2005-04-13 |
2009-02-26 |
Imbriglio Jason E |
Niacin receptor agonists, compositions containing such compounds and methods of treatment
|
ATE453656T1
(de)
|
2005-04-15 |
2010-01-15 |
Boehringer Ingelheim Int |
Glucopyranosyl-substituierte (heteroaryloxy- benzyl)-benzen-derivate als sglt-inhibitoren
|
DE102005017605B4
(de)
|
2005-04-16 |
2007-03-15 |
Sanofi-Aventis Deutschland Gmbh |
Substituierte 2-Aminoalkylthio-benzimidazole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
JP5094394B2
(ja)
|
2005-04-20 |
2012-12-12 |
武田薬品工業株式会社 |
縮合複素環化合物
|
DE102005018389A1
(de)
|
2005-04-20 |
2006-10-26 |
Sanofi-Aventis Deutschland Gmbh |
Azolderivate als Inhibitoren von Lipasen und Phospholipasen
|
WO2006121860A2
(en)
|
2005-05-06 |
2006-11-16 |
Bayer Pharmaceuticals Corporation |
Glucagon-like peptide 1 (glp-1) receptor agonists and their pharmacological methods of use
|
EA012442B1
(ru)
|
2005-05-13 |
2009-10-30 |
Эли Лилли Энд Компани |
Пегилированные соединения glp-1
|
WO2006124490A2
(en)
|
2005-05-17 |
2006-11-23 |
Schering Corporation |
Heterocycles as nicotinic acid receptor agonists for the treatment of dyslipidemia
|
US7906649B2
(en)
|
2005-05-25 |
2011-03-15 |
Merck Sharp & Dohme Corp. |
Aminocyclohexanes as dipeptidyl peptidase-IV inhibitors for the treatment of diabetes
|
TW200714597A
(en)
|
2005-05-27 |
2007-04-16 |
Astrazeneca Ab |
Chemical compounds
|
EP1889842A4
(en)
|
2005-06-08 |
2009-07-29 |
Japan Tobacco Inc |
HETEROCYCLIC CONNECTION
|
US7579360B2
(en)
|
2005-06-09 |
2009-08-25 |
Bristol-Myers Squibb Company |
Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors
|
MX2007016319A
(es)
|
2005-06-16 |
2008-03-10 |
Pfizer |
Derivados de n-(piridin-2-il)-sulfonamida.
|
WO2006134481A1
(en)
|
2005-06-16 |
2006-12-21 |
Pfizer Inc. |
Inhibitors of 11-beta hydroxysteroid dehydrogenase type 1
|
TW200726765A
(en)
|
2005-06-17 |
2007-07-16 |
Bristol Myers Squibb Co |
Triazolopyridine cannabinoid receptor 1 antagonists
|
WO2006133926A1
(en)
|
2005-06-17 |
2006-12-21 |
Carex Sa |
Pyrazole derivates as cannabinoid receptor modulators
|
US7605289B2
(en)
|
2005-06-17 |
2009-10-20 |
Amgen, Inc. |
Benzamide derivatives and uses related thereto
|
CA2612079A1
(en)
|
2005-06-22 |
2006-12-28 |
F. Hoffmann-La Roche Ag |
(6-flu0r0-benz0[1,3] dioxolyl)-morpholin-4-yl-methanones and their use as cb1 ligands
|
PE20070097A1
(es)
|
2005-06-28 |
2007-03-08 |
Merck Sharp & Dohme |
Agonistas del receptor de niacina y composiciones que contienen tales compuestos
|
WO2007000445A1
(en)
|
2005-06-29 |
2007-01-04 |
Boehringer Ingelheim International Gmbh |
Glucopyranosyl-substituted benzyl-benzene derivatives, medicaments containing such compounds, their use and process for their manufacture
|
AT8564U1
(de)
|
2005-06-29 |
2006-09-15 |
Plansee Se |
Halogenglühlampe mit abblendkappe aus mo-legierung
|
US20090325924A1
(en)
|
2005-06-30 |
2009-12-31 |
Stuart Edward |
GPCR Agonists
|
EP1909791A1
(en)
|
2005-06-30 |
2008-04-16 |
Prosidion Limited |
G-protein coupled receptor agonists
|
EP1904455B1
(en)
|
2005-07-05 |
2011-08-17 |
F. Hoffmann-La Roche AG |
Pyridazine derivatives
|
WO2007006760A1
(en)
|
2005-07-08 |
2007-01-18 |
Novo Nordisk A/S |
Dicycloalkyl urea glucokinase activators
|
JPWO2007007688A1
(ja)
|
2005-07-08 |
2009-01-29 |
持田製薬株式会社 |
3,5−ジアミノ−1,2,4−トリアゾール誘導体
|
WO2007007040A1
(en)
|
2005-07-09 |
2007-01-18 |
Astrazeneca Ab |
2 -heterocyclyloxybenzoyl amino heterocyclyl compounds as modulators of glucokinase for the treatment of type 2 diabetes
|
CA2613303C
(en)
|
2005-07-11 |
2012-06-19 |
Mitsubishi Tanabe Pharma Corporation |
An oxime derivative for use as a glucokinase activator
|
EP1905769B1
(en)
|
2005-07-13 |
2017-03-29 |
Msd K.K. |
Heterocycle-substituted benzimidazole derivative
|
US7884210B2
(en)
|
2005-07-14 |
2011-02-08 |
Novo Nordisk A/S |
Ureido-thiazole glucokinase activators
|
ATE432259T1
(de)
|
2005-07-20 |
2009-06-15 |
Lilly Co Eli |
Pyridinderivate als dipeptedyl-peptidase-hemmer
|
WO2007015744A1
(en)
|
2005-07-21 |
2007-02-08 |
Incyte Corporation |
Disubstituted thienyl compounds and their use as pharmaceuticals
|
EP1910359B1
(en)
|
2005-07-21 |
2009-11-18 |
F. Hoffmann-Roche AG |
PYRIDO [2 , 3-D]PYRIMIDINE-2 , 4-DIAMINE COMPOUNDS AS PTPlB INHIBITORS
|
UY29694A1
(es)
|
2005-07-28 |
2007-02-28 |
Boehringer Ingelheim Int |
Metodos para prevenir y tratar trastornos metabolicos y nuevos derivados de pirazol-o-glucosido
|
EP1916234B1
(en)
|
2005-07-29 |
2014-11-12 |
Takeda Pharmaceutical Company Limited |
Cyclopropanecarboxylic acid compound
|
FR2889190A1
(fr)
|
2005-08-01 |
2007-02-02 |
Merck Sante Soc Par Actions Si |
Nouveaux derives d'imidazoles carboxamides comme inhibiteurs de fructose -1,6-biphosphatase et compositions pharmaceutiques les contenant
|
ES2267400B1
(es)
|
2005-08-04 |
2008-03-01 |
Universitat De Valencia |
Composiciones pigmentarias en base acuosa para marcado policromatico de materiales inorganicos con laser.
|
JP2009504621A
(ja)
|
2005-08-09 |
2009-02-05 |
アストラゼネカ アクチボラグ |
糖尿病の処置のためのヘテロアリールカルバモイルベンゼン誘導体
|
AR055369A1
(es)
|
2005-08-10 |
2007-08-22 |
Smithkline Beecham Corp |
Compuestos derivados de xantina, su uso para preparar un medicamento para el tratamiento de una enfermedad mediada por el receptor hm74a, formulaciones y combinacion farmaceuticas que la comprenden y metodo de preparacion de los mismos
|
GB0516462D0
(en)
|
2005-08-10 |
2005-09-14 |
Smithkline Beecham Corp |
Novel compounds
|
JP5075125B2
(ja)
|
2005-08-26 |
2012-11-14 |
メルク・シャープ・エンド・ドーム・コーポレイション |
糖尿病の治療又は予防用ジペプチジルペプチダーゼiv阻害剤としての縮合アミノピペリジン
|
JP2009507791A
(ja)
|
2005-08-29 |
2009-02-26 |
メルク エンド カムパニー インコーポレーテッド |
ナイアシン受容体アゴニスト、このような化合物を含有する組成物、および治療方法
|
US20090281142A1
(en)
|
2005-08-31 |
2009-11-12 |
Astellas Pharma Inc. |
Thiazole derivative
|
JP2007063225A
(ja)
|
2005-09-01 |
2007-03-15 |
Takeda Chem Ind Ltd |
イミダゾピリジン化合物
|
WO2007028145A2
(en)
|
2005-09-02 |
2007-03-08 |
Dara Biosciences, Inc. |
Agents and methods for reducing protein tyrosine phosphatase 1b activity in the central nervous system
|
US20080300251A1
(en)
|
2005-09-05 |
2008-12-04 |
Sattigeri Jitendra A |
Derivatives of 3-Azabicyclo[3.1.0] Hexane as Dipeptidyl Peptidase-IV Inhibitors
|
MXPA05009633A
(es)
|
2005-09-08 |
2007-03-07 |
Silanes Sa De Cv Lab |
Composicion farmaceutica estable de glimepirida de liberacion inmediata y metformina de liberacion prolongada.
|
GB2429975A
(en)
|
2005-09-08 |
2007-03-14 |
Univ Edinburgh |
1,5-substituted-1H-tetrazole 11beta-hydroxysteroid dehydrogenase type 1 inhibitors
|
CA2621949A1
(en)
|
2005-09-14 |
2007-03-22 |
Amgen Inc. |
Conformationally constrained 3- (4-hydroxy-phenyl) - substituted-propanoic acids useful for treating metabolic disorders
|
CA2619093A1
(en)
|
2005-09-16 |
2007-03-29 |
Arena Pharmaceuticals, Inc. |
Modulators of metabolism and the treatment of disorders related thereto
|
US20090105263A1
(en)
|
2005-09-16 |
2009-04-23 |
Peter William Rodney Caulkett |
Heterobicyclic compounds as glucokinase activators
|
WO2007038138A2
(en)
|
2005-09-21 |
2007-04-05 |
Incyte Corporation |
Amido compounds and their use as pharmaceuticals
|
BRPI0616465A2
(pt)
|
2005-09-29 |
2011-06-21 |
Sanofi Aventis |
derivados de fenil-[1,2,4]-oxadiazol-5-ona com grupo fenila, bem como seu uso, composição farmacêutica compreendo os mesmos e processo de preparação da referida composição farmacêutica
|
GT200600429A
(es)
|
2005-09-30 |
2007-04-30 |
|
Compuestos organicos
|
AU2006295645B2
(en)
|
2005-09-30 |
2011-09-29 |
Msd K.K. |
2-heteroaryl-substituted indole derivative
|
GT200600428A
(es)
|
2005-09-30 |
2007-05-21 |
|
Compuestos organicos
|
DE102005048897A1
(de)
|
2005-10-12 |
2007-04-19 |
Sanofi-Aventis Deutschland Gmbh |
Diacylindazol-derivate als Inhibitoren von Lipasen und Phospholipasen
|
TW200745031A
(en)
|
2005-10-13 |
2007-12-16 |
Merck & Co Inc |
Acyl indoles, compositions containing such compounds and methods of use
|
JP2009013065A
(ja)
|
2005-10-14 |
2009-01-22 |
Astellas Pharma Inc |
縮合へテロ環化合物
|
EP1940393B1
(en)
|
2005-10-20 |
2012-07-25 |
Merck Sharp & Dohme Corp. |
Triazole derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase-1
|
CA2628274A1
(en)
|
2005-11-01 |
2007-05-10 |
Array Biopharma Inc. |
Glucokinase activators
|
EP1948190A2
(en)
|
2005-11-01 |
2008-07-30 |
Transtech Pharma |
Pharmaceutical use of substituted amides
|
JP2009513611A
(ja)
|
2005-11-01 |
2009-04-02 |
ハイ ポイント ファーマシューティカルズ,リミティド ライアビリティ カンパニー |
置換アミドの医薬用途
|
EP1960386A2
(en)
|
2005-11-01 |
2008-08-27 |
Janssen Pharmaceutica N.V. |
Substituted cycloalkylpyrrolones as allosteric modulators of glucokinase
|
CA2626475A1
(en)
|
2005-11-03 |
2007-05-10 |
Prosidion Limited |
Tricyclo substituted amides
|
BRPI0618067A2
(pt)
|
2005-11-03 |
2011-08-16 |
Prosidion Ltd |
composto ou um sal farmaceuticamente aceitável do mesmo, composição farmacêutica, e, uso e processo para a preparação de um composto ou um sal farmaceuticamente aceitável do mesmo
|
US20080293741A1
(en)
|
2005-11-03 |
2008-11-27 |
Matthew Colin Thor Fyfe |
Tricyclo Substituted Amides as Glucokinase Modulators
|
UA95613C2
(ru)
|
2005-11-09 |
2011-08-25 |
Уеллстат Терепьютикс Корпорейшн |
Соединения для лечения расстройсв метаболизма
|
US7696248B2
(en)
|
2005-11-17 |
2010-04-13 |
Eli Lilly And Company |
Glucagon receptor antagonists, preparation and therapeutic uses
|
PT1951658E
(pt)
|
2005-11-17 |
2012-11-12 |
Lilly Co Eli |
Antagonistas do receptor do glucagon, preparação e utilizações terapêuticas
|
WO2007057768A2
(en)
|
2005-11-18 |
2007-05-24 |
Pfizer Products Inc. |
Sulfonyl derivatives
|
WO2007061923A2
(en)
|
2005-11-18 |
2007-05-31 |
Takeda San Diego, Inc. |
Glucokinase activators
|
EP1953145B1
(en)
|
2005-11-21 |
2015-11-04 |
Shionogi & Co., Ltd. |
Heterocyclic compound having inhibitory activity on 11-b-hydroxysteroid dehydrogenase type i
|
EP1951696A2
(en)
|
2005-11-22 |
2008-08-06 |
Amgen Inc. |
Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1
|
EP1957068B1
(en)
|
2005-11-22 |
2014-08-13 |
Eli Lilly & Company |
Glucagon receptor antagonists, preparation and therapeutic uses
|
SI1957484T1
(sl)
|
2005-11-23 |
2010-07-30 |
Lilly Co Eli |
Antagonisti glukagonskega receptorja, priprava in terapevtske uporabe
|
WO2007060992A1
(ja)
|
2005-11-25 |
2007-05-31 |
Kaneka Corporation |
メタボリックシンドロームもしくはインスリン抵抗性症候群の予防または改善剤
|
WO2007063928A1
(ja)
|
2005-11-30 |
2007-06-07 |
Toray Industries, Inc. |
新規な非環状アミンカルボキシアミド誘導体及びその塩
|
CN1978445B
(zh)
|
2005-12-02 |
2010-09-01 |
中国科学院上海药物研究所 |
一种可用作人源腺苷单核苷酸激活蛋白激酶激活剂的化合物及其制备方法和应用
|
WO2007070506A2
(en)
|
2005-12-14 |
2007-06-21 |
Amgen Inc. |
Diaza heterocyclic sulfonamide derivatives and their uses
|
EP1962601B1
(en)
|
2005-12-14 |
2014-10-15 |
Merck Sharp & Dohme Corp. |
Fused aminopiperidines as dipeptidyl peptidase-4 inhibitors for the treatment or prevention of diabetes
|
EP1801098A1
(en)
|
2005-12-16 |
2007-06-27 |
Merck Sante |
2-Adamantylurea derivatives as selective 11B-HSD1 inhibitors
|
JP5270369B2
(ja)
|
2005-12-19 |
2013-08-21 |
タフツ ユニバーシティー/トラスティーズ オブ タフツ カレッジ |
ソフトプロテアーゼ抑制剤およびそのプロソフト型
|
EP1966152A2
(en)
|
2005-12-20 |
2008-09-10 |
Takeda Pharmaceutical Company Limited |
Glucokinase activators
|
WO2007071576A1
(en)
|
2005-12-21 |
2007-06-28 |
F. Hoffmann-La Roche Ag |
New salt and polymorph of dpp-iv inhibitor
|
EA201101085A1
(ru)
|
2005-12-22 |
2012-05-30 |
ХАЙ ПОЙНТ ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи |
Феноксиуксусные кислоты в качестве активаторов ppar дельта
|
JP2009520811A
(ja)
|
2005-12-22 |
2009-05-28 |
クリスタルジェノミクス、インコーポレイテッド |
プロテインキナーゼ活性を阻害するアミノピリミジン誘導体、及びその製造方法並びにこれを有効成分として含む医薬組成物
|
AU2006327069A1
(en)
|
2005-12-23 |
2007-06-28 |
Novartis Ag |
Condensed heterocyclic compounds useful as DPP-IV inhibitors
|
US20090156465A1
(en)
|
2005-12-30 |
2009-06-18 |
Sattigeri Jitendra A |
Derivatives of beta-amino acid as dipeptidyl peptidase-iv inhibitors
|
WO2007081755A2
(en)
|
2006-01-09 |
2007-07-19 |
Metabasis Therapeutics, Inc. |
Indole-benzimidazole and indazole inhibitors of tyrosine phosphatases
|
UY30082A1
(es)
|
2006-01-11 |
2007-08-31 |
Boehringer Ingelheim Int |
Forma cristalina de 1-(1-metiletil)-4`-((2-fluoro-4-metoxifenil)metil)-5`- metil-1h-pirazol-3`-o-b-d-glucopiranosido, un metodo para su preparacion y el uso de la misma para preparar medicamentos
|
US7932280B2
(en)
|
2006-01-13 |
2011-04-26 |
Merck Sharp & Dohme Corp. |
Triazole derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase-1
|
US20110178112A1
(en)
|
2006-01-18 |
2011-07-21 |
Evolva Sa |
PPAR Modulators
|
US20090170847A1
(en)
|
2006-01-23 |
2009-07-02 |
Seung Chul Lee |
Imidazopyridine Derivatives Inhibiting Protein Kinase Activity, Method for the Preparation Thereof and Pharmaceutical Composition Containing Same
|
CN101007798B
(zh)
|
2006-01-24 |
2011-01-26 |
中国人民解放军军事医学科学院毒物药物研究所 |
苯并间二氧杂环戊烯衍生物及其制备方法和医药用途
|
WO2007087231A2
(en)
|
2006-01-25 |
2007-08-02 |
Merck & Co., Inc. |
Aminocyclohexanes as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
|
CN101007804B
(zh)
|
2006-01-25 |
2011-05-11 |
中国人民解放军军事医学科学院毒物药物研究所 |
1,3-苯并间二氧杂环戊烯-2,2-二羧酸衍生物、其制备方法和医疗用途
|
CN101437512A
(zh)
|
2006-01-27 |
2009-05-20 |
阿雷生物药品公司 |
葡萄糖激酶活化剂
|
WO2007089557A2
(en)
|
2006-01-30 |
2007-08-09 |
Irm Llc |
Polycyclic 1, 2, 3, 4 -tetrahydro- isoquinoline derivatives and compositions comprising them as ppar modulators
|
CA2627692A1
(en)
|
2006-01-30 |
2007-08-02 |
Irm Llc |
Spiro imidazole derivatives as ppar modulators
|
KR20080086529A
(ko)
|
2006-01-30 |
2008-09-25 |
아이알엠 엘엘씨 |
Ppar 조절제로서의 화합물 및 조성물
|
KR20080091503A
(ko)
|
2006-01-31 |
2008-10-13 |
인사이트 코포레이션 |
아미도 화합물 및 약제로서의 이의 용도
|
US20090062269A1
(en)
|
2006-02-07 |
2009-03-05 |
Subharekha Raghavan |
Niacin Receptor Agonists, Compositions Containing Such Compounds and Methods of Treatment
|
WO2007092435A2
(en)
|
2006-02-07 |
2007-08-16 |
Wyeth |
11-beta hsd1 inhibitors
|
EP1983972A4
(en)
|
2006-02-13 |
2012-01-25 |
Wellstat Therapeutics Corp |
COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS
|
DE102006006648A1
(de)
|
2006-02-14 |
2007-08-23 |
Merck Patent Gmbh |
Mandelsäurehydrazide
|
CN101384555A
(zh)
*
|
2006-02-15 |
2009-03-11 |
塞诺菲-安万特股份有限公司 |
新的氨基醇取代的芳基二氢异喹啉酮类、其制备方法以及其作为药物的用途
|
JP5161795B2
(ja)
|
2006-02-15 |
2013-03-13 |
メルク・シャープ・エンド・ドーム・コーポレイション |
糖尿病の治療又は予防のためのジペプチジルペプチダーゼivインヒビターとしてのアミノテトラヒドロピラン
|
EP1989191B1
(en)
|
2006-02-15 |
2011-07-20 |
Boehringer Ingelheim International GmbH |
Glucopyranosyl-substituted benzonitrile derivatives, pharmaceutical compositions containing such compounds, their use and process for their manufacture
|
CA2633440C
(en)
|
2006-02-27 |
2011-06-21 |
Cadila Healthcare Limited |
1,3-dioxane carboxylic acids
|
AU2007220868B2
(en)
|
2006-02-28 |
2011-06-09 |
Wellstat Therapeutics Corporation |
Compounds for the treatment of metabolic disorders
|
WO2007099385A1
(en)
|
2006-03-01 |
2007-09-07 |
Glenmark Pharmaceuticals S.A. |
Dipeptidyl peptidase iv inhibitor compounds and compositions
|
US7834178B2
(en)
|
2006-03-01 |
2010-11-16 |
Bristol-Myers Squibb Company |
Triazine 11-beta hydroxysteroid dehydrogenase type 1 inhibitors
|
WO2007100027A1
(ja)
|
2006-03-02 |
2007-09-07 |
Daiichi Sankyo Company, Limited |
光学活性なチアゾリジンジオン誘導体
|
US20070213311A1
(en)
|
2006-03-02 |
2007-09-13 |
Yun-Long Li |
Modulators of 11-beta hydroxyl steroid dehydrogenase type 1, pharmaceutical compositions thereof, and methods of using the same
|
US20090264473A1
(en)
|
2006-03-03 |
2009-10-22 |
Zhiguo Jake Song |
Novel Crystalline Forms of Antidiabetic Compounds
|
WO2007103719A2
(en)
|
2006-03-03 |
2007-09-13 |
Incyte Corporation |
MODULATORS OF 11-β HYDROXYL STEROID DEHYDROGENASE TYPE 1, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME
|
US20070270492A1
(en)
|
2006-03-06 |
2007-11-22 |
Avestha Gengraine Technologies Pvt. Ltd. |
Nananoic acid derivatives as dipeptidyl peptidase inhibitors
|
US20080051452A1
(en)
|
2006-03-06 |
2008-02-28 |
Avestha Gengraine Technologies Pvt. Ltd. |
Hexanoic acid derivatives as dipeptidyl peptidase inhibitors
|
JP2009132620A
(ja)
|
2006-03-07 |
2009-06-18 |
Astellas Pharma Inc |
フェニルチアゾール誘導体
|
JP5302012B2
(ja)
|
2006-03-08 |
2013-10-02 |
タケダ カリフォルニア インコーポレイテッド |
グルコキナーゼ活性剤
|
CN101454325A
(zh)
|
2006-03-09 |
2009-06-10 |
法马科皮亚公司 |
用于治疗代谢性疾病的8-杂芳基嘌呤mnk2抑制剂
|
WO2007101864A2
(en)
|
2006-03-09 |
2007-09-13 |
High Point Pharmaceuticals, Llc |
Compounds that modulate ppar activity, their preparation and use
|
WO2007105650A1
(ja)
|
2006-03-10 |
2007-09-20 |
Ajinomoto Co., Inc. |
4-ヒドロキシイソロイシン誘導体および同誘導体の製造方法
|
EP2001844A2
(en)
|
2006-03-14 |
2008-12-17 |
Amgen, Inc |
Bicyclic carboxylic acid derivatives useful for treating metabolic disorders
|
CN101400698A
(zh)
|
2006-03-15 |
2009-04-01 |
诺沃-诺迪斯克有限公司 |
胰岛淀粉样多肽衍生物
|
US20090082367A1
(en)
|
2006-03-16 |
2009-03-26 |
Astellas Pharma Inc. |
Triazole derivative or a salt thereof
|
JP5243696B2
(ja)
|
2006-03-17 |
2013-07-24 |
田辺三菱製薬株式会社 |
ベンゼン誘導体
|
WO2007107550A1
(en)
|
2006-03-21 |
2007-09-27 |
High Point Pharmaceuticals, Llc |
Adamantane derivatives for the treatment of the metabolic syndrome
|
MY149622A
(en)
|
2006-03-22 |
2013-09-13 |
Hoffmann La Roche |
Pyrazoles as 11-beta-hsd-1
|
JP2009530381A
(ja)
|
2006-03-23 |
2009-08-27 |
メルク エンド カムパニー インコーポレーテッド |
グルカゴン受容体アンタゴニスト化合物、この化合物を含む組成物及び使用方法
|
AU2007231594A1
(en)
|
2006-03-23 |
2007-10-04 |
Amgen Inc. |
1-phenylsulfonyl-diaza heterocyclic amide compounds and their uses as modulators of hydroxsteroid dehydrogenases
|
FR2898894B1
(fr)
|
2006-03-24 |
2008-06-06 |
Genfit Sa |
Composes derives de n-(phenethyl)benzamide substitues, preparation et utilisations
|
TWI393718B
(zh)
|
2006-03-24 |
2013-04-21 |
Array Biopharma Inc |
葡萄糖激酶活化劑
|
FR2898892A1
(fr)
|
2006-03-24 |
2007-09-28 |
Genfit Sa |
Derives de n-(phenethyl)benzamide substitues,preparation et utilisations
|
JP2007291075A
(ja)
|
2006-03-27 |
2007-11-08 |
Sankyo Co Ltd |
新規化合物ステレニン及びその製造方法
|
WO2007112347A1
(en)
|
2006-03-28 |
2007-10-04 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
TW200806669A
(en)
|
2006-03-28 |
2008-02-01 |
Merck & Co Inc |
Aminotetrahydropyrans as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes
|
DE102006014688A1
(de)
|
2006-03-28 |
2007-10-04 |
Sanofi-Aventis |
Azolopyridin-3-on-derivate als Inhibitoren von Lipasen und Phospholipasen
|
GB0606429D0
(en)
|
2006-03-30 |
2006-05-10 |
Novartis Ag |
Organic compounds
|
AU2007233709A1
(en)
|
2006-03-31 |
2007-10-11 |
Novartis Ag |
Organic compounds
|
EP2038267A2
(en)
|
2006-03-31 |
2009-03-25 |
Novartis AG |
Thiadiazolidinone inhibitors of ptpase
|
MX2008012756A
(es)
|
2006-04-03 |
2009-03-05 |
Matrix Lab Ltd |
Inhibidores de dipeptidil peptidasa iv novedosos y procesos para su preparacion y composiciones farmaceuticas que los contienen.
|
WO2007114532A1
(en)
|
2006-04-03 |
2007-10-11 |
Industry-Academic Cooperation Foundation Gyeongsang National University |
Novel chalcone derivatives, pharmaceutically acceptable salt, method for preparation and uses thereof
|
CN101050194B
(zh)
|
2006-04-05 |
2013-08-21 |
上海恒瑞医药有限公司 |
双环辛烷类衍生物、其制备方法及其在医药上的用途
|
CA2646676A1
(en)
|
2006-04-06 |
2007-10-18 |
Prosidion Limited |
Heterocyclic gpcr agonists
|
JP5302883B2
(ja)
|
2006-04-07 |
2013-10-02 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
医薬組成物用のmnk1/mnk2阻害活性を有するチエノピリミジン
|
US7435833B2
(en)
|
2006-04-07 |
2008-10-14 |
Abbott Laboratories |
Inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme
|
CA2648074A1
(en)
|
2006-04-07 |
2007-10-18 |
High Point Pharmaceuticals, Llc |
11.beta.-hydroxysteroid dehydrogenase type 1 active compounds
|
GB0607196D0
(en)
|
2006-04-11 |
2006-05-17 |
Prosidion Ltd |
G-protein coupled receptor agonists
|
EP2010512A4
(en)
|
2006-04-11 |
2010-02-24 |
Merck & Co Inc |
NIACIN RECEPTOR AGONISTS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT
|
TW200806627A
(en)
|
2006-04-11 |
2008-02-01 |
Novartis Ag |
Organic compounds
|
JP2009533393A
(ja)
|
2006-04-12 |
2009-09-17 |
プロビオドルグ エージー |
酵素阻害薬
|
CA2649302A1
(en)
|
2006-04-12 |
2007-10-25 |
Wyeth |
Anilino-pyrimidine phenyl and benzothiophene analogs
|
WO2007120899A2
(en)
|
2006-04-13 |
2007-10-25 |
Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. |
Pharmaceutical compositions of hglp-1, exendin-4 and analogs thereof
|
WO2007119837A1
(ja)
|
2006-04-14 |
2007-10-25 |
Ajinomoto Co., Inc. |
リパーゼ阻害剤
|
JP2007284090A
(ja)
|
2006-04-14 |
2007-11-01 |
Dic Plastics Inc |
蓋体の係止構造および容器
|
PL2014652T3
(pl)
|
2006-04-18 |
2015-02-27 |
Nippon Chemiphar Co |
Czynnik aktywujący receptor aktywowany przez proliferatory peroksysomów
|
UY30288A1
(es)
|
2006-04-18 |
2007-08-31 |
Janssen Pharmaceutica Nv |
Derivados del ácido benzoazepin-oxi-acético como agonistas de ppar-delta usados para aumentar hdl-c. reducir ldl-c y reducir colesterol
|
WO2007120102A1
(en)
|
2006-04-19 |
2007-10-25 |
Astrazeneca Ab |
New substituted oxindole derivatives
|
US7842713B2
(en)
|
2006-04-20 |
2010-11-30 |
Pfizer Inc |
Fused phenyl amido heterocyclic compounds
|
WO2007122970A1
(ja)
|
2006-04-20 |
2007-11-01 |
Osaka University |
核内受容体に結合するリガンド
|
US8288339B2
(en)
|
2006-04-20 |
2012-10-16 |
Amgen Inc. |
GLP-1 compounds
|
EP2463283B1
(en)
|
2006-04-20 |
2014-06-11 |
Pfizer Products Inc. |
Fused phenyl Amido heterocyclic compounds for the prevention and treatment of glucokinase-mediated diseases
|
JP5236628B2
(ja)
|
2006-04-21 |
2013-07-17 |
イーライ リリー アンド カンパニー |
11−β−ヒドロキシステロイドデヒドロゲナーゼ1阻害剤としての、シクロヘキシルイミダゾールラクタム誘導体
|
CN101426783B
(zh)
|
2006-04-21 |
2013-10-30 |
伊莱利利公司 |
作为11-β-羟基甾族化合物脱氢酶1的抑制剂的环己基吡唑-内酰胺衍生物
|
MX2008013485A
(es)
|
2006-04-21 |
2008-10-30 |
Lilly Co Eli |
Derivados de lactamas de bifenilamida como inhibidores de 11-beta-hidroxiesteroide deshidrogenasa 1.
|
TW200815377A
(en)
|
2006-04-24 |
2008-04-01 |
Astellas Pharma Inc |
Oxadiazolidinedione compound
|
DK2049475T3
(da)
|
2006-04-24 |
2012-03-05 |
Lilly Co Eli |
Cyclohexyl-substituerede pyrrolidinoner som inhibitorer af 11-beta-hydroxysteroid dehydrogenase1
|
AU2007244960B2
(en)
|
2006-04-24 |
2012-03-01 |
Eli Lilly And Company |
Substituted pyrrolidinones as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
|
PL2021336T3
(pl)
|
2006-04-24 |
2010-11-30 |
Lilly Co Eli |
Inhibitory dehydrogenazy 11-ß- hydroksysteroidowej typu 1
|
WO2007122634A2
(en)
|
2006-04-24 |
2007-11-01 |
Jubilant Biosys Limited |
Pyrimidinediones as tyrosine kinase inhibitors
|
EA016360B1
(ru)
|
2006-04-25 |
2012-04-30 |
Эли Лилли Энд Компани |
Ингибиторы 11-бета-гидроксистероид дегидрогеназы 1, фармацевтическая композиция на их основе и их применение
|
EA015499B1
(ru)
|
2006-04-25 |
2011-08-30 |
Эли Лилли Энд Компани |
Ингибиторы 11-бета-гидроксистероид дегидрогеназы типа 1
|
DK2021337T3
(da)
|
2006-04-25 |
2010-03-29 |
Lilly Co Eli |
Inhibitorer af 11-beta-hydroxysteroid-dehydrogenase-1
|
WO2007122411A1
(en)
|
2006-04-26 |
2007-11-01 |
Astrazeneca Ab |
Diazepan-1-yl-sulfonyl derivatives for the treatment of metabolic syndrome
|
WO2007126043A1
(ja)
|
2006-04-27 |
2007-11-08 |
Mitsubishi Tanabe Pharma Corporation |
チアゾール環を含むカルボン酸誘導体の医薬用途
|
JP2009535318A
(ja)
|
2006-04-28 |
2009-10-01 |
トランステック ファーマ,インコーポレイティド |
ベンズアミドグルコキナーゼ活性化剤
|
EP1849785A1
(en)
|
2006-04-28 |
2007-10-31 |
Neuropharma, S.A. |
N-(2-Thiazolyl)-amide derivatives as GSK-3 inhibitors
|
CN101448816B
(zh)
|
2006-04-28 |
2013-08-07 |
伊莱利利公司 |
作为11-β-羟类固醇脱氢酶1的抑制剂的哌啶基取代的吡咯烷酮类
|
DE602007010764D1
(en)
|
2006-04-28 |
2011-01-05 |
Transtech Pharma Inc |
Benzamidglucokinaseaktivatoren
|
CA2649677A1
(en)
|
2006-05-01 |
2007-11-15 |
Incyte Corporation |
Tetrasubstituted ureas as modulators of 11-.beta. hydroxyl steroid dehydrogenase type 1
|
JP2009167103A
(ja)
|
2006-05-02 |
2009-07-30 |
Taisho Pharmaceutical Co Ltd |
ピラゾリル5−チオグリコシド化合物
|
JP2009167104A
(ja)
|
2006-05-02 |
2009-07-30 |
Taisho Pharmaceutical Co Ltd |
フェニル5−チオグリコシド化合物
|
EP1854806A1
(en)
|
2006-05-02 |
2007-11-14 |
MPG Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Thioglycosides as pharmaceutically active agents
|
EP1852108A1
(en)
|
2006-05-04 |
2007-11-07 |
Boehringer Ingelheim Pharma GmbH & Co.KG |
DPP IV inhibitor formulations
|
CA2810839A1
(en)
|
2006-05-04 |
2007-11-15 |
Boehringer Ingelheim International Gmbh |
A polymorphic form of 1-[(4-methyl-quinazolin-2-yl)methyl]-3-methyl-7-(2-butyn-1-yl)-8-(3-(r)-amino-piperidin-1-yl)-xanthine
|
ES2471978T3
(es)
|
2006-05-05 |
2014-06-27 |
Isis Pharmaceuticals, Inc. |
Compuestos y procedimientos para modular la expresión de ApoB
|
WO2007128801A1
(en)
|
2006-05-08 |
2007-11-15 |
Novartis Ag |
Combination of organic compounds
|
JP5269766B2
(ja)
|
2006-05-09 |
2013-08-21 |
ノボ・ノルデイスク・エー/エス |
インスリン誘導体
|
CA2649235A1
(en)
|
2006-05-09 |
2007-11-15 |
Frantisek Hubalek |
Insulin derivative
|
DE102006021872B4
(de)
|
2006-05-11 |
2008-04-17 |
Sanofi-Aventis |
4,5-Diphenyl-pyrimidinyl-oxy oder -mercapto substituierte Carbonsäuren, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
DE102006021878A1
(de)
|
2006-05-11 |
2007-11-15 |
Sanofi-Aventis |
Phenylamino-benzoxazol substituierte Carbonsäuren, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
BRPI0711416A2
(pt)
|
2006-05-11 |
2011-11-01 |
Sanofi Aventis |
ácidos carboxìlicos substituìdos com 4,5-difenil pirimidinila, processo para a produção e uso dos mesmos como medicamentos
|
DE102006021874B4
(de)
|
2006-05-11 |
2008-03-27 |
Sanofi-Aventis |
4,5-Diphenyl-pyrimidinyl-amino substituierte Carbonsäuren, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
US7851468B2
(en)
|
2006-05-15 |
2010-12-14 |
Cephalon, Inc. |
Substituted pyrazolo[3,4-d]pyrimidines
|
EP2021327B1
(en)
|
2006-05-15 |
2012-04-04 |
Merck Sharp & Dohme Corp. |
Antidiabetic bicyclic compounds
|
WO2007136577A2
(en)
|
2006-05-16 |
2007-11-29 |
Merck & Co., Inc. |
Glucagon receptor antagonist compounds, compositions containing such compounds and methods of use
|
CA2652367A1
(en)
|
2006-05-16 |
2007-11-29 |
Merck & Co., Inc. |
Aminotetrahydropyrans as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
|
WO2007137066A2
(en)
|
2006-05-17 |
2007-11-29 |
Incyte Corporation |
HETEROCYCLIC INHIBITORS OF 11-β HYDROXYL STEROID DEHYDROGENASE TYPE I AND METHODS OF USING THE SAME
|
JP2009537559A
(ja)
|
2006-05-18 |
2009-10-29 |
ウェルスタット セラピューティクス コーポレイション |
代謝障害の処置のための化合物
|
EP2076503B1
(en)
|
2006-05-19 |
2013-07-17 |
Taisho Pharmaceutical Co., Ltd |
C-phenyl glycitol compound for the treatment of diabetes
|
ES2344086T3
(es)
|
2006-05-23 |
2010-08-17 |
F. Hoffmann-La Roche Ag |
Derivados de piridopirimidinona.
|
JP5230613B2
(ja)
|
2006-05-23 |
2013-07-10 |
テラコス・インコーポレイテッド |
グルコース輸送体阻害剤およびその使用方法
|
WO2007135427A1
(en)
|
2006-05-23 |
2007-11-29 |
Astrazeneca Ab |
1,4-disubstituted piperazine and 1,4-disubstituted azepane as 11 -beta-hydroxysteroid dehydrogenase 1 inhibitors
|
JP5105297B2
(ja)
|
2006-05-25 |
2012-12-26 |
味の素株式会社 |
Ppar活性調節剤
|
EP2021011A2
(en)
|
2006-05-26 |
2009-02-11 |
Nestec S.A. |
Methods of use and nutritional compositions of touchi extract
|
MX2008015008A
(es)
|
2006-05-26 |
2008-12-05 |
Novartis Ag |
INHIBIDORES DE SINTASA DE ALDOSTERONA Y/O DE 11ß-HIDROXILASA.
|
WO2007143434A2
(en)
|
2006-05-31 |
2007-12-13 |
Takeda San Diego, Inc. |
Indazole and isoindole derivatives as glucokinase activating agents
|
CA2652162A1
(en)
|
2006-06-01 |
2007-12-06 |
Marcel Gubler |
Thiazole derivatives
|
FR2901792A1
(fr)
|
2006-06-06 |
2007-12-07 |
Negma Lerads Soc Par Actions S |
DERIVES ACTIVATEURS DE PPARs, PROCEDE DE PREPARATION ET APPLICATION EN THERAPEUTIQUE
|
JP2009190971A
(ja)
|
2006-06-06 |
2009-08-27 |
Mitsubishi Tanabe Pharma Corp |
2−シアノピロリジン誘導体
|
US20070287674A1
(en)
|
2006-06-08 |
2007-12-13 |
Hej Research Institute Of Chemistry |
New treatment of diabetes mellitus
|
ATE476418T1
(de)
|
2006-06-08 |
2010-08-15 |
Amgen Inc |
Benzamidderivate und assoziierte verwendungen
|
TW200808695A
(en)
|
2006-06-08 |
2008-02-16 |
Amgen Inc |
Benzamide derivatives and uses related thereto
|
WO2007146761A2
(en)
|
2006-06-12 |
2007-12-21 |
Neurogen Corporation |
Diaryl pyrimidinones and related compounds
|
WO2008035359A2
(en)
|
2006-06-12 |
2008-03-27 |
Cadila Healthcare Limited |
Oximinophenoxyalkanoic acid and phenylalkanoic acid derivatives
|
US20090306048A1
(en)
|
2006-06-16 |
2009-12-10 |
John Paul Kilburn |
Pharmaceutical use of substituted piperidine carboxamides
|
WO2007149865A2
(en)
|
2006-06-19 |
2007-12-27 |
University Of Utah Research Foundation |
Methods and compositions related to inhibition of ceramide synthesis
|
WO2007148185A2
(en)
|
2006-06-21 |
2007-12-27 |
Pfizer Products Inc. |
Substituted 3 -amino- pyrrolidino-4 -lactams as dpp inhibitors
|
DE102006028862A1
(de)
|
2006-06-23 |
2007-12-27 |
Merck Patent Gmbh |
3-Amino-imidazo[1,2-a]pyridinderivate
|
BRPI0713619A2
(pt)
|
2006-06-23 |
2013-01-15 |
Incyte Corp |
composto ou prà-droga ou sal farmaceuticamente aceitÁvel do mesmo, composiÇço, e, uso do composto.
|
WO2007150026A2
(en)
|
2006-06-23 |
2007-12-27 |
Incyte Corporation |
Purinone derivatives as hm74a agonists
|
TW200815418A
(en)
|
2006-06-27 |
2008-04-01 |
Astrazeneca Ab |
New compounds I
|
TW200811170A
(en)
|
2006-06-27 |
2008-03-01 |
Sanofi Aventis |
Urea derivatives of tropane, their preparation and their therapeutic application
|
RU2444521C2
(ru)
|
2006-06-27 |
2012-03-10 |
Такеда Фармасьютикал Компани Лимитед |
Конденсированные циклические соединения
|
TW200815417A
(en)
|
2006-06-27 |
2008-04-01 |
Astrazeneca Ab |
New compounds II
|
TW200811158A
(en)
|
2006-06-27 |
2008-03-01 |
Sanofi Aventis |
Piperidine or pyrrolidine urea derivatives, their preparation and their therapeutic application
|
US7919598B2
(en)
|
2006-06-28 |
2011-04-05 |
Bristol-Myers Squibb Company |
Crystal structures of SGLT2 inhibitors and processes for preparing same
|
US20080004281A1
(en)
|
2006-06-28 |
2008-01-03 |
Kalypsys, Inc. |
Methods for the modulation of crp by the selective modulation of ppar delta
|
BRPI0713058A2
(pt)
|
2006-06-29 |
2012-04-10 |
Taisho Pharmaceutical Co., Ltd. |
composto de 1-tioglucitol de c-fenila
|
US20080004325A1
(en)
|
2006-06-29 |
2008-01-03 |
Wyeth |
PTP1B inhibitors
|
BRPI0714200A2
(pt)
|
2006-07-05 |
2012-12-25 |
Hoffmann La Roche |
composto derivado de alquil-piridazina, processo para a sua preparaÇço, composiÇço farmacÊutica que compreende o mesmo, seu uso e mÉtodos para o tratamento e/ou profilaxia de enfermidades
|
TW200811147A
(en)
|
2006-07-06 |
2008-03-01 |
Arena Pharm Inc |
Modulators of metabolism and the treatment of disorders related thereto
|
WO2008005910A2
(en)
|
2006-07-06 |
2008-01-10 |
Bristol-Myers Squibb Company |
Pyridone/hydroxypyridine 11-beta hydroxysteroid dehydrogenase type i inhibitors
|
US7910747B2
(en)
|
2006-07-06 |
2011-03-22 |
Bristol-Myers Squibb Company |
Phosphonate and phosphinate pyrazolylamide glucokinase activators
|
US7888504B2
(en)
|
2006-07-06 |
2011-02-15 |
Bristol-Myers Squibb Company |
Glucokinase activators and methods of using same
|
TW200811140A
(en)
|
2006-07-06 |
2008-03-01 |
Arena Pharm Inc |
Modulators of metabolism and the treatment of disorders related thereto
|
JP5194588B2
(ja)
|
2006-07-06 |
2013-05-08 |
大正製薬株式会社 |
1−チオ−d−グルシトール誘導体を有効成分として含有する糖尿病の予防又は治療剤
|
US20080009534A1
(en)
|
2006-07-07 |
2008-01-10 |
Bristol-Myers Squibb Company |
Substituted acid derivatives useful as antidiabetic and antiobesity agents and method
|
CN101100458A
(zh)
|
2006-07-07 |
2008-01-09 |
上海艾力斯医药科技有限公司 |
具有PPARγ激动剂活性的双苯并咪唑衍生物及其应用
|
US7795291B2
(en)
|
2006-07-07 |
2010-09-14 |
Bristol-Myers Squibb Company |
Substituted acid derivatives useful as anti-atherosclerotic, anti-dyslipidemic, anti-diabetic and anti-obesity agents and method
|
FR2903404B1
(fr)
|
2006-07-10 |
2008-08-22 |
Servier Lab |
Nouveaux derives tetracycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
|
EP2044073A1
(en)
|
2006-07-13 |
2009-04-08 |
High Point Pharmaceuticals, LLC |
11beta-hydroxysteroid dehydrogenase type 1 active compounds
|
US8222261B2
(en)
|
2006-07-13 |
2012-07-17 |
GlaxoSmithKline, LLC |
Chemical compounds
|
FR2903695B1
(fr)
|
2006-07-13 |
2008-10-24 |
Merck Sante Soc Par Actions Si |
Utilisation de derives d'imidazole activateurs de l'ampk, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
|
EP1878721A1
(en)
|
2006-07-13 |
2008-01-16 |
Novo Nordisk A/S |
4-Piperidylbenzamides as 11-beta-hydroxysteroid dehydrogenase type 1 inhibitors
|
US20100010530A1
(en)
|
2006-07-14 |
2010-01-14 |
Ams Research Corporation |
Balloon Dilation for Implantable Prosthesis
|
JP5372318B2
(ja)
|
2006-07-14 |
2013-12-18 |
パナソニック株式会社 |
電気化学キャパシタの製造方法
|
DE102006033140A1
(de)
|
2006-07-18 |
2008-01-24 |
Merck Patent Gmbh |
Aminoindazolharnstoffderivate
|
CA2659155A1
(en)
|
2006-07-20 |
2008-01-24 |
Amgen Inc. |
Substituted azole aromatic heterocycles as inhibitors of 11.beta.-hsd-1
|
US8594202B2
(en)
|
2006-07-21 |
2013-11-26 |
Vidyo, Inc. |
Systems and methods for signaling and performing temporal level switching in scalable video coding
|
AU2007274598A1
(en)
|
2006-07-21 |
2008-01-24 |
Lupin Limited |
Antidiabetic azabicyclo [3. 1. 0] hexan compounds
|
FR2903984B1
(fr)
|
2006-07-24 |
2008-10-03 |
Genfit Sa |
Derives d'imidazolones substitues, preparation et utilisations
|
JP2008031064A
(ja)
|
2006-07-27 |
2008-02-14 |
Astellas Pharma Inc |
ジアシルピペラジン誘導体
|
TWI418556B
(zh)
|
2006-07-27 |
2013-12-11 |
Mitsubishi Tanabe Pharma Corp |
吲哚衍生物
|
TWI432446B
(zh)
|
2006-07-27 |
2014-04-01 |
Chugai Pharmaceutical Co Ltd |
稠環螺酮縮醇衍生物、及其做為糖尿病治療藥之使用
|
TWI403516B
(zh)
|
2006-07-27 |
2013-08-01 |
Chugai Pharmaceutical Co Ltd |
To replace spirocyclic alcohol derivatives, and its use as a therapeutic agent for diabetes
|
WO2008012532A2
(en)
|
2006-07-27 |
2008-01-31 |
Astrazeneca Ab |
: pyridine-3-carboxamide compounds and their use for inhibiting 11-beta-hydroxysteroid dehydrogenase
|
US20080027014A1
(en)
|
2006-07-28 |
2008-01-31 |
Tanabe Seiyaku Co., Ltd. |
Novel SGLT inhibitors
|
WO2008016730A2
(en)
|
2006-08-02 |
2008-02-07 |
Targeted Molecular Diagnostics, Llc |
Compositions and methods for reducing cellular fat
|
WO2008016968A2
(en)
|
2006-08-03 |
2008-02-07 |
Trustees Of Tufts College |
Non-flushing niacin analogues, and methods of use thereof
|
US8492378B2
(en)
|
2006-08-03 |
2013-07-23 |
Takeda Pharmaceutical Company Limited |
GSK-3β inhibitor
|
JPWO2008016175A1
(ja)
|
2006-08-03 |
2009-12-24 |
日本ケミファ株式会社 |
ペルオキシソーム増殖剤活性化受容体の活性化剤
|
WO2008019309A1
(en)
|
2006-08-04 |
2008-02-14 |
Metabasis Therapeutics, Inc. |
Novel inhibitors of fructose 1,6-bisphosphatase
|
TW200817424A
(en)
|
2006-08-04 |
2008-04-16 |
Daiichi Sankyo Co Ltd |
Benzylphenyl glucopyranoside derivatives
|
KR100826108B1
(ko)
|
2006-08-04 |
2008-04-29 |
한국화학연구원 |
퓨란-2-카복실산 유도체 및 그의 제조 방법
|
EP1887006A1
(en)
|
2006-08-07 |
2008-02-13 |
Krka |
Polymorphic forms of rosiglitazone base
|
EP2057160A1
(en)
|
2006-08-08 |
2009-05-13 |
Boehringer Ingelheim International GmbH |
Pyrrolo [3, 2 -d]pyrimidines as dpp-iv inhibitors for the treatment of diabetes mellitus
|
WO2008022015A2
(en)
|
2006-08-11 |
2008-02-21 |
Trustees Of Tufts College |
Retro-inverso incretin analogues, and methods of use thereof
|
CA2656847A1
(en)
|
2006-08-15 |
2008-02-21 |
Boehringer Ingelheim International Gmbh |
Glucopyranosyl-substituted cyclopropylbenzene derivatives, pharmaceutical compositions containing such compounds, their use as sglt inhibitors and process for their manufacture
|
JP2009256208A
(ja)
|
2006-08-17 |
2009-11-05 |
Dainippon Sumitomo Pharma Co Ltd |
フタリド誘導体またはその薬学的に許容される塩
|
JP5399244B2
(ja)
|
2006-08-17 |
2014-01-29 |
アミリン・ファーマシューティカルズ,リミテッド・ライアビリティ・カンパニー |
選択可能な特性を持つdpp−iv耐性gipハイブリッドポリペプチド
|
EP2057141B1
(en)
|
2006-08-23 |
2011-10-26 |
Pfizer Products Inc. |
Pyrimidone compounds as gsk-3 inhibitors
|
US7727978B2
(en)
|
2006-08-24 |
2010-06-01 |
Bristol-Myers Squibb Company |
Cyclic 11-beta hydroxysteroid dehydrogenase type I inhibitors
|
WO2008024497A2
(en)
|
2006-08-25 |
2008-02-28 |
Vitae Pharmaceuticals, Inc. |
INHIBITORS OF 11β -HYDROXYSTEROID DEHYDROGENASE TYPE 1
|
WO2008029217A2
(en)
|
2006-08-29 |
2008-03-13 |
Orchid Research Laboratories Limited |
Dipeptidyl peptidase iv inhibitors
|
US20080058339A1
(en)
|
2006-08-30 |
2008-03-06 |
Biovitrum |
New compounds
|
CL2007002499A1
(es)
|
2006-08-30 |
2008-03-14 |
Phenomix Corp |
Sales citrato y tartrato de compuestos derivados de acido pirrolidinilaminoacetilpirrolidinboronico, inhibidores de dpp-iv; metodo de preparacion; forma solida; combinacion farmaceutica, util para el tratamiento de diabetes.
|
US8268818B2
(en)
|
2006-09-01 |
2012-09-18 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of C-MET and uses thereof
|
WO2008028188A2
(en)
|
2006-09-01 |
2008-03-06 |
The Ticket Reserve |
Demand aggregation for future items contingent upon threshold demand
|
JP2008063256A
(ja)
|
2006-09-06 |
2008-03-21 |
Astellas Pharma Inc |
β‐アミノ酸誘導体
|
EP2064193A1
(en)
|
2006-09-07 |
2009-06-03 |
Amgen, Inc |
Heterocyclic gpr40 modulators
|
US7687526B2
(en)
|
2006-09-07 |
2010-03-30 |
Amgen Inc. |
Benzo-fused compounds for use in treating metabolic disorders
|
WO2008028662A1
(en)
|
2006-09-07 |
2008-03-13 |
Santhera Pharmaceuticals (Schweiz) Ag |
N-[1-(3-amino-4-phenyl-butyryl)-4-hydroxy-pyrrolidin-2-ylmethyl}-propionamide and related compounds as dpp-iv inhibitors for the treatment of type 2 diabetes mellitus
|
WO2008032164A2
(en)
|
2006-09-12 |
2008-03-20 |
Pfizer Products Inc. |
Benzimidazolone derivatives
|
WO2008033931A1
(en)
|
2006-09-13 |
2008-03-20 |
The Institutes For Pharmaceutical Discovery, Llc |
Para-xylylene carboxylic acids and isothiazolones useful as protein tyrosine phosphatases (ptps) in particular ptp-ib
|
WO2008033932A2
(en)
|
2006-09-13 |
2008-03-20 |
The Institutes For Pharmaceutical Discovery, Llc |
Biarylthiazole carboxylic acid derivatives as protein tyrosine phosphatase-ib inhibitors
|
AU2007296556B2
(en)
|
2006-09-13 |
2013-09-19 |
Takeda Pharmaceutical Company Limited |
Use of 2-6- (3-Amino-piperidin-1-yl) -3-methyl-2, 4-dioxo-3, 4-dihydro-2H-pyrimidin-1-ylmethyl-4-fluoro-benzonitrile
|
WO2008033455A2
(en)
|
2006-09-13 |
2008-03-20 |
The Institutes For Pharmaceutical Discovery, Llc |
Biphenyl and heteroaryl phenyl derivatives as protein tyrosine phosphatases inhibitors
|
WO2008033934A1
(en)
|
2006-09-13 |
2008-03-20 |
The Institutes For Pharmaceutical Discovery, Llc |
Substituted heteroaryl carboxylic acid derivatives as ptb-1b inhibitors
|
US20100016274A1
(en)
|
2006-09-14 |
2010-01-21 |
Koppel Gary A |
Beta-lactam cannabinoid receptor modulators
|
CA2664095A1
(en)
|
2006-09-21 |
2008-03-27 |
Boehringer Ingelheim International Gmbh |
Glucopyranosyl-substituted difluorobenzyl-benzene derivatives, medicaments containing such compounds, their use and process for their manufacture
|
PT2074141T
(pt)
|
2006-09-22 |
2016-11-10 |
Novo Nordisk As |
Análogos de insulina resistentes a proteases
|
TWI499414B
(zh)
|
2006-09-29 |
2015-09-11 |
Lexicon Pharmaceuticals Inc |
鈉與葡萄糖第2型共同運輸體(co-transporter 2)的抑制物與其應用方法
|
KR101077309B1
(ko)
|
2006-09-29 |
2011-10-26 |
에프. 호프만-라 로슈 아게 |
설폰아미드 유도체
|
WO2008039882A1
(en)
|
2006-09-30 |
2008-04-03 |
Sanofi-Aventis U.S. Llc |
A combination of niacin and a prostaglandin d2 receptor antagonist
|
TW200821284A
(en)
|
2006-10-03 |
2008-05-16 |
Merck & Co Inc |
Glucagon receptor antagonist compounds, compositions containing such compounds and methods of use
|
AU2007323035B2
(en)
|
2006-10-03 |
2011-11-24 |
Cadila Healthcare Limited |
Antidiabetic compounds
|
WO2008044656A1
(fr)
|
2006-10-06 |
2008-04-17 |
Taisho Pharmaceutical Co., Ltd. |
Dérivé d'imidazolidinone
|
AR063028A1
(es)
|
2006-10-06 |
2008-12-23 |
Banyu Pharma Co Ltd |
Derivados heterociclicos de piridin-2-carboxamida activadores de glucoquinasas, utiles para el tratamiento de diabetes y obesidad y composiciones farmaceuticas que los contienen.
|
WO2008040974A1
(en)
|
2006-10-07 |
2008-04-10 |
Peakdale Molecular Limited |
Indoles for use as dpp-iv inhibitors
|
CA2675511A1
(en)
|
2006-10-10 |
2008-04-17 |
Amgen Inc. |
N-aryl pyrazole compounds for use against diabetes
|
EP1911747A1
(en)
|
2006-10-11 |
2008-04-16 |
Laboratorios del Dr. Esteve S.A. |
Sulfonamide substituted pyrazoline compounds, their preparation and use as CB1 modulators
|
WO2008044700A1
(fr)
|
2006-10-11 |
2008-04-17 |
Takeda Pharmaceutical Company Limited |
INHIBITEUR DE LA GSK-3β
|
US20080107725A1
(en)
|
2006-10-13 |
2008-05-08 |
Albano Antonio A |
Pharmaceutical Solid Dosage Forms Comprising Amorphous Compounds Micro-Embedded in Ionic Water-Insoluble Polymers
|
US7705005B2
(en)
|
2006-10-13 |
2010-04-27 |
Glaxo Group Limited |
Bicyclic heteroaromatic compounds
|
WO2008044762A1
(fr)
|
2006-10-13 |
2008-04-17 |
Chugai Seiyaku Kabushiki Kaisha |
Dérivé de spirocétal de thioglucose et utilisation de celui-ci comme agent thérapeutique pour le diabète
|
DE102006048728A1
(de)
|
2006-10-16 |
2008-04-17 |
Merck Patent Gmbh |
3-Amino-imidazo{1,2-a]pyridinderivate
|
US8492405B2
(en)
|
2006-10-18 |
2013-07-23 |
Takeda Pharmaceutical Company Limited |
Glucokinase-activating fused heterocyclic compounds and methods of treating diabetes and obesity
|
NZ576570A
(en)
|
2006-10-19 |
2010-11-26 |
Takeda Pharmaceutical |
7-sulfonylamino-2-thiazol and 2-thiadiazol -indole compounds
|
RU2439062C2
(ru)
|
2006-10-19 |
2012-01-10 |
Ф.Хоффманн-Ля Рош Аг |
Производные имидазолона и имидазолидинона как 11в-hsd1 ингибиторы при диабете
|
CA2667002A1
(en)
|
2006-10-20 |
2008-05-02 |
Merck & Co., Inc. |
Niacin receptor agonists, compositions containing such compounds and methods of treatment
|
TW200825063A
(en)
|
2006-10-23 |
2008-06-16 |
Astrazeneca Ab |
Chemical compounds
|
KR100812538B1
(ko)
|
2006-10-23 |
2008-03-11 |
한올제약주식회사 |
약물 제어방출형 메트포르민-글리메피리드 복합제제
|
US20080103201A1
(en)
|
2006-10-26 |
2008-05-01 |
Wijayabandara Mirihanage Don J |
Novel alpha-Glucosidase inhibitor from Tabernaemontana dichotoma
|
CL2007003061A1
(es)
|
2006-10-26 |
2008-08-01 |
Astrazeneca Ab |
Compuestos derivados de 3,5-dioxi-benzamida; proceso de preparacion; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar una enfermedad mediada a traves de glk, tal como la diabetes tipo 2.
|
WO2008049711A1
(en)
|
2006-10-27 |
2008-05-02 |
Novo Nordisk A/S |
Peptide extended insulins
|
EP2086991A1
(en)
|
2006-10-27 |
2009-08-12 |
Boehringer Ingelheim International GmbH |
CRYSTALLINE FORM OF 4-(ß-D-GLUCOPYRANOS-1-YL)-1-METHYL-2-[4-((S)-TETRAHYDROFURAN-3-YLOXY)-BENZYL]-BENZENE, A METHOD FOR ITS PREPARATION AND THE USE THEREOF FOR PREPARING MEDICAMENTS
|
US8039484B2
(en)
|
2006-10-31 |
2011-10-18 |
Merck Sharp & Dohme Corp. |
Antidiabetic bicyclic compounds
|
WO2008054674A2
(en)
|
2006-10-31 |
2008-05-08 |
Merck & Co., Inc. |
Antidiabetic bicyclic compounds
|
JP2010508358A
(ja)
|
2006-11-01 |
2010-03-18 |
ブリストル−マイヤーズ スクイブ カンパニー |
グルココルチコイド受容体、AP−1、および/またはNF−κB活性の調節剤、並びにその使用
|
WO2008057862A2
(en)
|
2006-11-01 |
2008-05-15 |
Bristol-Myers Squibb Company |
MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-ϰB ACTIVITY AND USE THEREOF
|
EP2089389A2
(en)
|
2006-11-01 |
2009-08-19 |
Bristol-Myers Squibb Company |
Heterocyclic compounds as modulators of glucocorticoid receptor, ap-1, and/or nf-kappa-b activity
|
US8067447B2
(en)
|
2006-11-01 |
2011-11-29 |
Bristol-Myers Squibb Company |
Modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
|
CA2667211A1
(en)
|
2006-11-01 |
2008-05-08 |
Pronova Biopharma Norge As |
Alpha-substituted omega-3 lipids that are activators or modulators of the peroxisome proliferators-activated receptor (ppar)
|
ATE550337T1
(de)
|
2006-11-01 |
2012-04-15 |
Bristol Myers Squibb Co |
Modulatoren der glucocorticoidrezeptor-, ap-1- und/oder nf-kappa-b-aktivität und deren verwendung
|
JP2010509231A
(ja)
|
2006-11-02 |
2010-03-25 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
プロテインキナーゼの阻害剤として有用なアミノピリジンおよびアミノピリミジン
|
EP2077846B1
(en)
|
2006-11-02 |
2011-10-12 |
Piramal Life Sciences Limited |
Benzoxazepine compounds, their preparation and use
|
EP1918285A1
(en)
|
2006-11-03 |
2008-05-07 |
Merck Sante |
Diazepane-acetamide derivatives as selective 11beta-HSD1 inhibitors
|
TW200827346A
(en)
|
2006-11-03 |
2008-07-01 |
Astrazeneca Ab |
Chemical compounds
|
WO2008055870A1
(en)
|
2006-11-06 |
2008-05-15 |
Boehringer Ingelheim International Gmbh |
Glucopyranosyl-substituted benzyl-benzonitrile derivatives, medicaments containing such compounds, their use and process for their manufacture
|
EP1921080B1
(en)
|
2006-11-07 |
2009-08-05 |
Sanofi-Aventis |
Subsitituted 8-piperidinyl-2-pyridinyl-pyrimido(1,2-a)pyrimidin-6-one and 8-piperidinyl-2-pyrimidinyl-pyrimido(1,2-a)pyrimidin-6-one derivatives
|
MY157828A
(en)
|
2006-11-09 |
2016-07-29 |
Boehringer Ingelheim Int |
Combination therapy with sglt-2 inhibitors and their pharmaceutical compositions
|
JP2010043001A
(ja)
|
2006-11-09 |
2010-02-25 |
Sanwa Kagaku Kenkyusho Co Ltd |
Glp−1誘導体とその用途
|
JP4898635B2
(ja)
|
2006-11-14 |
2012-03-21 |
参天製薬株式会社 |
置換フェニルアミノ低級アルキル基とエステル構造を導入したフェニル基を置換基として有する新規1,2−ジヒドロキノリン誘導体
|
JP5232160B2
(ja)
|
2006-11-14 |
2013-07-10 |
メルク・シャープ・アンド・ドーム・コーポレーション |
糖尿病の治療又は予防のためのジペプチジルペプチダーゼivインヒビターとしての三環式芳香族複素環化合物
|
US7750048B2
(en)
|
2006-11-15 |
2010-07-06 |
Janssen Pharmaceutica Nv |
GPR40 agonists
|
EP2111865B1
(en)
|
2006-11-17 |
2019-10-02 |
National University Corporation Kagawa University |
Utilization of the function of rare sugar as promoter for the migration of glucokinase from nucleus to cytoplasm
|
EP2096111A1
(en)
|
2006-11-20 |
2009-09-02 |
Japan Tobacco Inc. |
Pyrazoles and use thereof as drugs
|
CN101595109B
(zh)
|
2006-11-20 |
2012-09-05 |
百时美施贵宝公司 |
作为二肽基肽酶ⅳ抑制剂的7,8-二氢-1,6-二氮杂萘-5(6h)-酮和相关二环化合物及方法
|
WO2008062273A2
(en)
|
2006-11-20 |
2008-05-29 |
Cadila Pharmaceuticals Limited |
Solid oral dosage form having antidiabetic drug combination
|
WO2008061355A1
(en)
|
2006-11-24 |
2008-05-29 |
Matregen Corp. |
Glp-1 depot systems, and methods of manufacture and uses thereof
|
WO2008066070A1
(fr)
|
2006-11-29 |
2008-06-05 |
Uha Mikakuto Co., Ltd. |
Inhibiteur de dipeptidylpeptidase-iv
|
JP4125768B2
(ja)
|
2006-11-30 |
2008-07-30 |
富士産業株式会社 |
α−グルコシダーゼ阻害剤
|
JP5405120B2
(ja)
|
2006-12-01 |
2014-02-05 |
Msd株式会社 |
新規フェニル−イソキサゾール−3−オール誘導体
|
TW200838526A
(en)
|
2006-12-01 |
2008-10-01 |
Astellas Pharma Inc |
Carboxylic acid derivatives
|
CN103086936A
(zh)
|
2006-12-02 |
2013-05-08 |
财团法人首尔大学校产学协力财团 |
作为ppar配体的芳基化合物及其用途
|
NZ577391A
(en)
|
2006-12-04 |
2011-11-25 |
Janssen Pharmaceutica Nv |
Thienyl-containing glycopyranosyl derivatives as antidiabetics
|
UY30730A1
(es)
|
2006-12-04 |
2008-07-03 |
Mitsubishi Tanabe Pharma Corp |
Forma cristalina del hemihidrato de 1-(b (beta)-d-glucopiranosil) -4-metil-3-[5-(4-fluorofenil) -2-tienilmetil]benceno
|
AR064106A1
(es)
|
2006-12-05 |
2009-03-11 |
Bayer Schering Pharma Ag |
Derivados de 2,3-dihidroimidazo [1,2-c] quinazolina sustituida utiles para el tratamiento de enfermedades y trastornos hiper-proliferativos asociados con la angiogenesis
|
JP2010512331A
(ja)
|
2006-12-06 |
2010-04-22 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
グルココルチコイド模倣薬、それらの製造方法、医薬組成物、及びこれらの使用
|
JP5330260B2
(ja)
|
2006-12-06 |
2013-10-30 |
スミスクライン ビーチャム コーポレーション |
二環式化合物ならびに抗糖尿病薬としての使用
|
DE102006058236A1
(de)
|
2006-12-11 |
2008-06-12 |
Merck Patent Gmbh |
Indolizinderivate
|
WO2008071169A2
(de)
|
2006-12-11 |
2008-06-19 |
Universitätsklinikum Schleswig-Holstein |
Verfahren zur herstellung spezifischer inhibitoren der 11beta-hydroxysteroid-dehydrogenase, insbesondere des typs 1, mit nor-oleanan- oder nor-ursan-grundgerüsten
|
CA2672059A1
(en)
|
2006-12-14 |
2008-06-26 |
Merck & Co., Inc. |
Acyl bipiperidinyl compounds, compositions containing such compounds and methods of treatment
|
EP1932843A1
(en)
|
2006-12-14 |
2008-06-18 |
sanofi-aventis |
Sulfonyl-phenyl-2H-(1,2,4) oxadiazole-5-one derivatives, processes for their preparation and their use as pharmaceuticals
|
US7902248B2
(en)
|
2006-12-14 |
2011-03-08 |
Hoffmann-La Roche Inc. |
Oxime glucokinase activators
|
JPWO2008072726A1
(ja)
|
2006-12-14 |
2010-04-02 |
大正製薬株式会社 |
1−フェニル 1−チオ−d−グルシト−ル誘導体
|
CA2672269A1
(en)
|
2006-12-18 |
2008-06-26 |
Novartis Ag |
Organic compounds
|
MX2009006481A
(es)
|
2006-12-18 |
2009-06-26 |
Novartis Ag |
Derivados de imidazol 1-sustituidos, y su uso como inhibidores de la sintasa de aldosterona.
|
CA2673368C
(en)
|
2006-12-19 |
2014-10-28 |
The Board Of Trustees Of The University Of Illinois |
3-benzofuranyl-4-indolyl maleimides as potent gsk3 inhibitors for neurogenerative disorders
|
EP2091947A2
(en)
|
2006-12-20 |
2009-08-26 |
Takeda San Diego, Inc. |
Glucokinase activators
|
EP2121661A1
(en)
|
2006-12-20 |
2009-11-25 |
Merck & Co., Inc. |
Bipiperidinyl compounds, compositions containing such compounds and methods of treatment
|
JPWO2008075741A1
(ja)
|
2006-12-20 |
2010-04-15 |
国立大学法人 長崎大学 |
糖尿病治療剤及び予防剤
|
EP1939187A1
(en)
|
2006-12-20 |
2008-07-02 |
Sanofi-Aventis |
Substituted heteroaryl pyridopyrimidone derivatives
|
EP1935420A1
(en)
|
2006-12-21 |
2008-06-25 |
Merck Sante |
2-Adamantyl-butyramide derivatives as selective 11beta-HSD1 inhibitors
|
AU2007343139A1
(en)
|
2006-12-21 |
2008-07-17 |
Pfizer Products Inc. |
Compounds having both angiotensin II receptor antagonism and PPARy activating activities
|
BRPI0721143A2
(pt)
|
2006-12-21 |
2014-03-11 |
Astrazeneca Ab |
Forma cristalina do composto processo para a formação da mesma, uso de um composto, método para tratar doenças mediadas por ativador de glicocinase
|
WO2008077597A1
(en)
|
2006-12-22 |
2008-07-03 |
Novartis Ag |
1-aminomethyl- l- phenyl- cyclohexane derivatives as ddp-iv inhibitors
|
TW200831081A
(en)
|
2006-12-25 |
2008-08-01 |
Kyorin Seiyaku Kk |
Glucokinase activator
|
US7932421B2
(en)
|
2006-12-26 |
2011-04-26 |
Amgen Inc. |
N-cyclohexyl benzamides and benzeneacetamides as inhibitors of 11-beta-hydroxysteroid dehydrogenases
|
JP2008156318A
(ja)
|
2006-12-26 |
2008-07-10 |
Dainippon Sumitomo Pharma Co Ltd |
1,3,4−オキサジアゾール−2−オン誘導体
|
WO2008078725A1
(ja)
|
2006-12-26 |
2008-07-03 |
Daiichi Sankyo Company, Limited |
チアゼピン誘導体
|
EP1939192A1
(en)
|
2006-12-28 |
2008-07-02 |
Neuropharma S.A. |
Cyclopentanone derivatives, method of synthesis and uses thereof
|
US7638541B2
(en)
|
2006-12-28 |
2009-12-29 |
Metabolex Inc. |
5-ethyl-2-{4-[4-(4-tetrazol-1-yl-phenoxymethyl)-thiazol-2-yl]-piperidin-1-yl}-pyrimidine
|
ES2627221T3
(es)
|
2006-12-28 |
2017-07-27 |
Rigel Pharmaceuticals, Inc. |
Compuestos de heterocicloalquiloxibenzamida N-sustituidos y métodos de uso
|
US7795228B2
(en)
|
2006-12-28 |
2010-09-14 |
Theracos, Inc. |
Spiroheterocyclic glycosides and methods of use
|
EP1939191A1
(en)
|
2006-12-28 |
2008-07-02 |
Neuropharma S.A. |
Furan derivatives, method of synthesis and uses thereof
|
FR2910893A1
(fr)
|
2006-12-29 |
2008-07-04 |
Genfit Sa |
Derives de (phenylthiazolyl)-phenyl-propan-1-one et de (phenyloxazolyl)-phenyl-propan-1-one substitues, preparations et utilisations.
|
FR2910894A1
(fr)
|
2006-12-29 |
2008-07-04 |
Genfit Sa |
Derives de 3-phenyl-1-(phenylthienyl)propan-1-one et de 3-phenyl-1-(phenylfuranyl)propan-1-one substitues, preparation et utilisation.
|
FR2910892A1
(fr)
|
2006-12-29 |
2008-07-04 |
Genfit Sa |
Derives de 1,3-diphenylpropane substitues, preparations et utilisations.
|
US20100063302A1
(en)
|
2007-01-03 |
2010-03-11 |
Takano Co., Ltd. |
Cyclic sulfonium salt, method for production of cyclic sulfonium salt, and glycosidase inhibitor
|
GB0700122D0
(en)
|
2007-01-04 |
2007-02-14 |
Prosidion Ltd |
GPCR agonists
|
WO2008081208A1
(en)
|
2007-01-04 |
2008-07-10 |
Prosidion Limited |
Piperidine gpcr agonists
|
CL2008000018A1
(es)
|
2007-01-04 |
2008-08-01 |
Prosidion Ltd |
Compuestos derivados de heterociclos de nitrogeno y oxigeno, agonistas de gpcr; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto para el tratamiento de la obesidad, diabetes, sindrome metabolico, hiperlipidemia, toleranci
|
AR064736A1
(es)
|
2007-01-04 |
2009-04-22 |
Prosidion Ltd |
Agonistas de gpcr
|
WO2008081204A1
(en)
|
2007-01-04 |
2008-07-10 |
Prosidion Limited |
Piperidine gpcr agonists
|
US20090098130A1
(en)
|
2007-01-05 |
2009-04-16 |
Bradshaw Curt W |
Glucagon-like protein-1 receptor (glp-1r) agonist compounds
|
FR2911137B1
(fr)
|
2007-01-05 |
2009-02-20 |
Sanofi Aventis Sa |
Nouveaux derives de 2,4-dianilinopyrimides, leur preparation a titre de medicaments, compositions pharmaceutiques et notamment comme inhibiteurs de ikk
|
FR2911138B1
(fr)
|
2007-01-05 |
2009-02-20 |
Sanofi Aventis Sa |
Nouveaux derives de n, n'-2,4-dianilinopyrimidines, leur preparation a titre de medicaments, compositions pharmaceutiques et notamment comme inhibiteurs de ikk
|
JP2008169195A
(ja)
|
2007-01-05 |
2008-07-24 |
Hanmi Pharmaceutical Co Ltd |
キャリア物質を用いたインスリン分泌ペプチド薬物結合体
|
FR2911139A1
(fr)
|
2007-01-05 |
2008-07-11 |
Sanofi Aventis Sa |
Nouveaux derives de phenyl-(4-phenyl-pyrimidin-2-yl)amines, leur preparation a titre de medicaments, compositions pharmaceutiques et notamment comme inhibiteurs de ikk
|
FR2911140B1
(fr)
|
2007-01-05 |
2009-02-20 |
Sanofi Aventis Sa |
Nouveaux derives de 2-anilino 4-heteroaryle pyrimides, leur preparation a titre de medicaments, compositions pharmaceutiques et notamment comme inhibiteurs de ikk
|
BRPI0807023A2
(pt)
|
2007-01-08 |
2014-04-22 |
Seoul Nat Univ Ind Foundation |
Composto de tiazol como ligante de ppard e produto farmacêutico, cosmético e alimento saudável dele composto
|
WO2008084043A1
(en)
|
2007-01-09 |
2008-07-17 |
Novo Nordisk A/S |
Urea glucokinase activators
|
WO2008084873A1
(ja)
|
2007-01-10 |
2008-07-17 |
Mitsubishi Tanabe Pharma Corporation |
オキシム誘導体
|
EP2105435A4
(en)
|
2007-01-10 |
2011-06-15 |
Mitsubishi Tanabe Pharma Corp |
Hydrazone derivatives
|
JP4328820B2
(ja)
|
2007-01-10 |
2009-09-09 |
田辺三菱製薬株式会社 |
医薬組成物
|
AU2008204530B2
(en)
|
2007-01-11 |
2013-08-01 |
Vtv Therapeutics Llc |
Urea glucokinase activators
|
WO2008087654A2
(en)
|
2007-01-16 |
2008-07-24 |
Cadila Healthcare Limited |
PIPERIDINES AS INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE TYPE 1
|
DE102007002260A1
(de)
|
2007-01-16 |
2008-07-31 |
Sanofi-Aventis |
Verwendung von substituierten Pyranonsäurederivaten zur Herstellung von Medikamenten zur Behandlung des Metabolischen Syndroms
|
KR100848491B1
(ko)
|
2007-01-16 |
2008-07-28 |
영진약품공업주식회사 |
베타아미노기를 갖는 2-싸이아졸리딘 유도체, 이의약학적으로 허용 가능한 염 및 이의 제조 방법
|
DE102007002717A1
(de)
|
2007-01-18 |
2008-07-24 |
Merck Patent Gmbh |
Heterocyclische Indazolderivate
|
JP2010516700A
(ja)
|
2007-01-18 |
2010-05-20 |
エヴォルヴァ エスアー |
置換1,3−ジオキサンおよびそれらの使用
|
AU2008206047B2
(en)
|
2007-01-18 |
2014-07-10 |
Evolva Sa |
Substituted 1,3-dioxanes useful as PPAR modulators
|
WO2008088006A1
(ja)
|
2007-01-19 |
2008-07-24 |
Shinji Yokoyama |
Ap2抑制剤
|
CN101230058A
(zh)
|
2007-01-23 |
2008-07-30 |
上海恒瑞医药有限公司 |
双环氮杂烷类衍生物、其制备方法及其在医药上的用途
|
EP2120959A4
(en)
|
2007-01-23 |
2010-05-26 |
Reddys Lab Ltd Dr |
METHOD AND COMPOSITIONS FOR TREATING INSULIN RESISTANCE, DIABETES AND DIABETES-BASED DYSLIPIDEMIA
|
US20080176861A1
(en)
|
2007-01-23 |
2008-07-24 |
Kalypsys, Inc. |
Sulfonyl-substituted bicyclic compounds as ppar modulators for the treatment of non-alcoholic steatohepatitis
|
WO2008091770A1
(en)
|
2007-01-24 |
2008-07-31 |
Array Biopharma Inc. |
2-aminopyridine derivatives as glucokinase activators
|
AR065033A1
(es)
|
2007-01-26 |
2009-05-13 |
Boehringer Ingelheim Int |
Metodos para prevenir y tratar trastornos neurodegenerativos
|
TW200843785A
(en)
|
2007-01-26 |
2008-11-16 |
Boehringer Ingelheim Int |
Methods for preventing and treating neurodegenerative disorders
|
NZ578296A
(en)
|
2007-01-26 |
2012-07-27 |
Kaneq Pharma Inc |
Fused aromatic ptp-1b inhibitors
|
JP2010516721A
(ja)
|
2007-01-26 |
2010-05-20 |
サノフィ−アベンティス |
フェノチアジン誘導体、その製造方法及び医薬としてその使用
|
JPWO2008093639A1
(ja)
|
2007-01-29 |
2010-05-20 |
武田薬品工業株式会社 |
ピラゾール化合物
|
KR20080071476A
(ko)
|
2007-01-30 |
2008-08-04 |
주식회사 엘지생명과학 |
신규한 디펩티딜 펩티데이즈 iv(dpp-iv) 저해제
|
JP2010518014A
(ja)
|
2007-01-31 |
2010-05-27 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
キナーゼ阻害剤として有用な2−アミノピリジン誘導体
|
WO2008096260A1
(en)
|
2007-02-07 |
2008-08-14 |
Pfizer Inc. |
3-amino-pyrrolo[3,4-c] pyrazole- 5 (1h, 4h, 6h) carbaldehyde derivatives as pkc inhibitors
|
EP1988091B1
(en)
|
2007-02-07 |
2015-06-10 |
Kyowa Hakko Kirin Co., Ltd. |
Tricyclic compounds
|
WO2008096820A1
(ja)
|
2007-02-07 |
2008-08-14 |
Kyowa Hakko Kirin Co., Ltd. |
ビフェニル誘導体
|
US20100260841A1
(en)
|
2007-02-08 |
2010-10-14 |
Paolini John F |
Method of Treating Atherosclerosis, Dyslipidemias and Related Conditions
|
WO2008096769A1
(ja)
|
2007-02-08 |
2008-08-14 |
Daiichi Sankyo Company, Limited |
置換されたセルコスポラミド誘導体を含有する医薬
|
TW200838512A
(en)
|
2007-02-08 |
2008-10-01 |
Daiichi Sankyo Co Ltd |
Crystalline forms of a thiazolidinedione compound and manufacturing methods thereof
|
CA2894112C
(en)
|
2007-02-09 |
2020-09-15 |
Metabasis Therapeutics, Inc. |
Novel antagonists of the glucagon receptor
|
WO2008099448A1
(ja)
|
2007-02-09 |
2008-08-21 |
Masayoshi Yamaguchi |
糖尿病性疾患の予防・治療剤
|
JP2010120851A
(ja)
|
2007-02-09 |
2010-06-03 |
Kyorin Pharmaceut Co Ltd |
二量化シクロ誘導体
|
AU2008215490A1
(en)
|
2007-02-09 |
2008-08-21 |
Takeda Pharmaceutical Company Limited |
Fused ring compounds as partial agonists of PPAR-gamma
|
TW200836719A
(en)
|
2007-02-12 |
2008-09-16 |
Astrazeneca Ab |
Chemical compounds
|
MX2009008241A
(es)
|
2007-02-15 |
2009-10-08 |
Univ Indiana Res & Tech Corp |
Co-agonistas de receptor de glucagon/glp-1.
|
DE102007007751A1
(de)
|
2007-02-16 |
2008-08-21 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue substituierte Arylsulfonylglycine, deren Herstellung und deren Verwendung als Arzneimittel
|
DE102007008420A1
(de)
|
2007-02-21 |
2008-08-28 |
Merck Patent Gmbh |
Benzimidazolderivate
|
JP2010519273A
(ja)
|
2007-02-21 |
2010-06-03 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
四置換グルコピラノシル化ベンゼン誘導体、このような化合物を含む薬物、それらの使用及びそれらの製造方法
|
MX2009008921A
(es)
|
2007-02-22 |
2009-08-28 |
Irm Llc |
Derivados de tiazole en la forma de moduladores de receptores acoplados por proteina g.
|
EP1961742A1
(en)
|
2007-02-22 |
2008-08-27 |
Novartis AG |
compounds of formula (I) as serine protease inhibitors
|
JP5175866B2
(ja)
|
2007-02-22 |
2013-04-03 |
アイアールエム・リミテッド・ライアビリティ・カンパニー |
Gタンパク質共役受容体を調節するための化合物および方法
|
EA016951B1
(ru)
|
2007-02-23 |
2012-08-30 |
ХАЙ ПОЙНТ ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи |
N-АДАМАНТИЛБЕНЗАМИДЫ В КАЧЕСТВЕ ИНГИБИТОРОВ 11-β-ГИДРОКСИСТЕРОИДДЕГИДРОГЕНАЗЫ
|
WO2008101886A1
(en)
|
2007-02-23 |
2008-08-28 |
High Point Pharmaceuticals, Llc |
N-adamantyl benzamides as inhibitors of 11-beta-hydroxysteroid dehydrogenase
|
JP2010519242A
(ja)
|
2007-02-23 |
2010-06-03 |
ハイ ポイント ファーマシューティカルズ,リミティド ライアビリティ カンパニー |
新規化合物
|
WO2008101885A1
(en)
|
2007-02-23 |
2008-08-28 |
High Point Pharmaceuticals, Llc |
N-adamantyl benzamides as inhibitors of 11-beta-hydroxysteroid dehydrogenase
|
CA2678577A1
(en)
|
2007-02-26 |
2008-09-04 |
Vitae Pharmaceuticals, Inc. |
Cyclic urea and carbamate inhibitors of 11.beta.-hydroxysteroid dehydrogenase 1
|
DE102007009494A1
(de)
|
2007-02-27 |
2008-08-28 |
Bayer Healthcare Ag |
Substituierte 4-Aryl-1, 4-dihydro-1,6-naphthyridinamide und ihre Verwendung
|
EP2125735B1
(en)
|
2007-02-28 |
2012-06-27 |
Advinus Therapeutics Private Limited |
2,2,2-tri-substituted acetamide derivatives as glucokinase activators, their process and pharmaceutical application
|
WO2008109334A1
(en)
|
2007-03-02 |
2008-09-12 |
Merck & Co., Inc. |
Novel crystalline salt form of an antidiabetic compound
|
WO2008111473A1
(ja)
|
2007-03-07 |
2008-09-18 |
Kyorin Pharmaceutical Co., Ltd. |
グルコキナーゼ活性化物質
|
WO2008108602A1
(en)
|
2007-03-07 |
2008-09-12 |
Dong-A Pharm. Co., Ltd. |
Novel phenylpropionic acid derivatives as peroxisome proliferator-activated gamma receptor modulators, method of the same, and pharmaceutical composition comprising the same
|
PE20090159A1
(es)
|
2007-03-08 |
2009-02-21 |
Plexxikon Inc |
COMPUESTOS DERIVADOS DE ACIDO INDOL-PROPIONICO COMO MODULADORES PPARs
|
EP2121591A2
(en)
|
2007-03-08 |
2009-11-25 |
Plexxikon, Inc. |
Ppar active compounds
|
ATE482209T1
(de)
|
2007-03-08 |
2010-10-15 |
Irm Llc |
Verbindungen und zusammensetzungen als modulatoren der gpr119-aktivität
|
PL2125711T3
(pl)
|
2007-03-08 |
2014-05-30 |
Albireo Ab |
Pochodne kwasy 3-fenylopropionowego oraz ich zastosowanie w leczeniu nieswoistego zapalenia jelit
|
CN101652359A
(zh)
|
2007-03-09 |
2010-02-17 |
高点制药有限责任公司 |
作为羟类固醇脱氢酶抑制剂的吲哚-和苯并咪唑酰胺类
|
EP2137183B1
(en)
|
2007-03-09 |
2011-09-28 |
Vertex Pharmaceuticals Incorporated |
Aminopyrimidines useful as inhibitors of protein kinases
|
CN101260103A
(zh)
|
2007-03-09 |
2008-09-10 |
上海艾力斯医药科技有限公司 |
一类具有部分PPARγ激动剂活性的化合物及其应用
|
ES2435997T3
(es)
|
2007-03-09 |
2013-12-26 |
Vertex Pharmaceuticals, Inc. |
Aminopirimidinas útiles como inhibidores de las proteínas cinasas
|
WO2008112938A2
(en)
|
2007-03-13 |
2008-09-18 |
New England Medical Center Hospitals, Inc. |
Composition and method for the treatment of diseases affected by a peptide receptor
|
DE102007012645A1
(de)
|
2007-03-16 |
2008-09-18 |
Bayer Healthcare Ag |
Substituierte Imidazo- und Triazolopyrimidine
|
DE102007012284A1
(de)
|
2007-03-16 |
2008-09-18 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue substituierte Arylsulfonylglycine, deren Herstellung und deren Verwendung als Arzneimittel
|
EP1972349A1
(en)
|
2007-03-21 |
2008-09-24 |
Biocompatibles UK Limited |
GLP-1 fusion peptides conjugated to polymer(s), their production and use
|
WO2008116107A2
(en)
|
2007-03-21 |
2008-09-25 |
Takeda San Diego, Inc. |
Piperazine derivatives as glucokinase activators
|
TW200904454A
(en)
|
2007-03-22 |
2009-02-01 |
Bristol Myers Squibb Co |
Methods for treating obesity employing an SGLT2 inhibitor and compositions thereof
|
TW200904405A
(en)
|
2007-03-22 |
2009-02-01 |
Bristol Myers Squibb Co |
Pharmaceutical formulations containing an SGLT2 inhibitor
|
WO2008116294A1
(en)
|
2007-03-23 |
2008-10-02 |
Matregen Corp. |
Exendin analogs
|
WO2008118848A1
(en)
|
2007-03-23 |
2008-10-02 |
Trustees Of Tufts College |
N-substituted peptidomimetic inhibitors of dipeptidylpeptidase iv
|
MX2009010218A
(es)
|
2007-03-23 |
2009-10-19 |
Hoffmann La Roche |
Derivados de aza-piridopirimidinona.
|
US8362037B2
(en)
|
2007-03-23 |
2013-01-29 |
Array Biopharma, Inc. |
2-aminopyridine analogs as glucokinase activators
|
WO2008119005A1
(en)
|
2007-03-27 |
2008-10-02 |
Trustees Of Tufts College |
3,4-dehydro-proline-containing inhibitors of dipeptidylpeptidase iv
|
EP1975176A1
(en)
|
2007-03-27 |
2008-10-01 |
Biocompatibles UK Limited |
Novel glp-1 fusion peptides, their production and use
|
CA2681934A1
(en)
|
2007-03-28 |
2008-10-02 |
High Point Pharmaceuticals, Llc |
11beta-hsd1 active compounds
|
WO2008117982A1
(en)
|
2007-03-28 |
2008-10-02 |
Crystal Genomics, Inc. |
Heterocyclic carboxylic acid derivatives and pharmaceutical composition for inhibiting lipid accumulation containing same
|
JP2010522732A
(ja)
|
2007-03-29 |
2010-07-08 |
ナームローゼ・フエンノートチヤツプ・オルガノン |
鉱質コルチコイド受容体アンタゴニスト
|
CN101274918A
(zh)
|
2007-03-30 |
2008-10-01 |
中国科学院上海药物研究所 |
一类取代五元杂环化合物,其制备方法和医学用途
|
US8133898B2
(en)
|
2007-03-30 |
2012-03-13 |
Takeda Pharmaceutical Company Limited |
Renin inhibitors
|
EP2142542A4
(en)
|
2007-03-30 |
2011-06-22 |
Astrazeneca Ab |
NEW IMIDAZO [4,5-B] PYRIDINE-7-CARBOXYLAMIDEAMIDE 704
|
WO2008121064A1
(en)
|
2007-03-30 |
2008-10-09 |
Astrazeneca Ab |
New imidazo[4,5-b]pyridine-6-halo-7-aryl/heteroaryl compounds 705
|
JP2010138073A
(ja)
|
2007-03-30 |
2010-06-24 |
Taisho Pharmaceutical Co Ltd |
ピコリン酸アミド化合物
|
US7998992B2
(en)
|
2007-03-30 |
2011-08-16 |
Institute Of Medicinal Molecular Design, Inc. |
Oxazolidinone derivative having inhibitory activity on 11β-hydroxysteroid dehydrogenase type 1
|
RU2492175C2
(ru)
|
2007-04-02 |
2013-09-10 |
Теракос, Инк. |
Бензиловые производные гликозидов и способы их применения
|
CN101279955B
(zh)
|
2007-04-03 |
2012-11-28 |
北京摩力克科技有限公司 |
作为二肽肽激酶-iv抑制剂的n-取代硫吗啉衍生物及其医药用途
|
AU2008233548B2
(en)
|
2007-04-03 |
2011-12-01 |
Mitsubishi Tanabe Pharma Corporation |
Combined use of dipeptidyl peptidase IV inhibitor compound and sweetener
|
JP5294419B2
(ja)
|
2007-04-05 |
2013-09-18 |
第一三共株式会社 |
縮合二環式ヘテロアリール誘導体
|
WO2008126731A1
(ja)
|
2007-04-05 |
2008-10-23 |
Daiichi Sankyo Company, Limited |
アリール誘導体
|
EP2144885B1
(de)
|
2007-04-05 |
2016-06-29 |
Sanofi |
Imidazolidin-carbonsäureamid-derivate als inhibitoren von lipasen und phospholipasen
|
EP2144891B1
(de)
|
2007-04-05 |
2016-06-15 |
Sanofi |
5-oxo-isoxazole als inhibitoren von lipasen und phospholipasen
|
US20100048950A1
(en)
|
2007-04-10 |
2010-02-25 |
Boehringer Ingelheim International Gmbh |
Glucocorticoid Mimetics, Methods of Making Them, Pharmaceutical Compositions and Uses Thereof
|
WO2008124665A1
(en)
|
2007-04-10 |
2008-10-16 |
Boehringer Ingelheim International Gmbh |
Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
|
ES2399912T3
(es)
|
2007-04-11 |
2013-04-04 |
High Point Pharmaceuticals, Llc |
Nuevos compuestos
|
GB0707087D0
(en)
|
2007-04-12 |
2007-05-23 |
Piramed Ltd |
Pharmaceutical compounds
|
JP2010523639A
(ja)
|
2007-04-12 |
2010-07-15 |
エフ.ホフマン−ラ ロシュ アーゲー |
医薬化合物
|
JP2010523637A
(ja)
|
2007-04-12 |
2010-07-15 |
エフ.ホフマン−ラ ロシュ アーゲー |
医薬化合物
|
CN104370914B
(zh)
|
2007-04-12 |
2018-09-07 |
辉瑞大药厂 |
作为蛋白酶c抑制剂的3-酰氨基-吡咯并[3,4-c]吡唑-5(1h,4h,6h)甲醛衍生物
|
PE20090695A1
(es)
|
2007-04-13 |
2009-06-27 |
Schering Corp |
Derivados de pirimidindiona como agonistas del receptor de acido nicotinico
|
CA2683751C
(en)
|
2007-04-16 |
2013-01-08 |
Amgen Inc. |
Substituted biphenyl phenoxy-, thiophenyl- and aminophenylpropanoic acid gpr40 modulators
|
US8546394B2
(en)
|
2007-04-17 |
2013-10-01 |
Bristol-Myers Squibb Company |
Substituted [1,2,4]triazolo[4,3-A]pyrazine 11-beta-hydroxysteroid dehydrogenase inhibitors
|
KR20090129479A
(ko)
|
2007-04-18 |
2009-12-16 |
아스트라제네카 아베 |
화합물 2-히드록시-3-[5-(모르폴린-4-일메틸)피리딘-2-일]1h-인돌-5-카르보니트릴 701의 신규 제조 방법
|
AU2008241692B2
(en)
|
2007-04-19 |
2011-02-10 |
Dong-A Pharm. Co., Ltd. |
DPP-IV inhibitor including beta-amino group, preparation method thereof and pharmaceutical composition containing the same for preventing and treating a diabetes or an obesity
|
CA2684618A1
(en)
|
2007-04-20 |
2008-10-30 |
Schering Corporation |
Tetrahydropyrido[4,3-d]pyrimidinone derivatives and methods of use thereof
|
WO2008130581A1
(en)
|
2007-04-20 |
2008-10-30 |
Schering Corporation |
Pyrimidinone derivatives and methods of use thereof
|
PE20090696A1
(es)
|
2007-04-20 |
2009-06-20 |
Bristol Myers Squibb Co |
Formas cristalinas de saxagliptina y procesos para preparar las mismas
|
WO2008130584A1
(en)
|
2007-04-20 |
2008-10-30 |
Schering Corporation |
Pyrimidinone derivatives and methods of use thereof
|
JP2010526777A
(ja)
|
2007-04-24 |
2010-08-05 |
ハイ ポイント ファーマシューティカルズ,リミティド ライアビリティ カンパニー |
置換アミドの医薬用途
|
JP2010159210A
(ja)
|
2007-04-26 |
2010-07-22 |
Dainippon Sumitomo Pharma Co Ltd |
縮合複素環誘導体
|
EP2154131A4
(en)
|
2007-04-26 |
2011-09-21 |
Pharmafrontier Co Ltd |
INHIBITOR OF THE G-PROTEIN-COUPLED RECEPTOR AND PHARMACEUTICAL PRODUCT
|
WO2008136393A1
(ja)
|
2007-04-27 |
2008-11-13 |
Ajinomoto Co., Inc. |
ラクタム化合物の結晶形およびその製造方法
|
JPWO2008136428A1
(ja)
|
2007-04-27 |
2010-07-29 |
武田薬品工業株式会社 |
含窒素5員複素環化合物
|
CN101668759A
(zh)
|
2007-05-04 |
2010-03-10 |
百时美施贵宝公司 |
[6,5]-双环gpr119g蛋白-偶合受体激动剂
|
PE20090222A1
(es)
|
2007-05-04 |
2009-03-27 |
Bristol Myers Squibb Co |
Compuestos [6,6] y [6,7]-biciclicos como agonistas del receptor acoplado a la proteina g gpr119
|
KR20080099174A
(ko)
|
2007-05-07 |
2008-11-12 |
주식회사 머젠스 |
비만, 당뇨, 대사성 질환, 퇴행성 질환 및 미토콘드리아이상 질환의 치료 또는 예방을 위한 나프토퀴논계 약제조성물
|
JP2010526807A
(ja)
|
2007-05-07 |
2010-08-05 |
メルク・シャープ・エンド・ドーム・コーポレイション |
抗糖尿病活性を有する縮合芳香族化合物を用いた治療法
|
DE102007022565A1
(de)
|
2007-05-14 |
2008-11-20 |
Merck Patent Gmbh |
Heterocyclische Indazolderivate
|
EP1992620A1
(en)
|
2007-05-16 |
2008-11-19 |
Sanofi-Aventis |
Arylamide pyrimidone derivatives for the treatment of neurodegenerative diseases
|
EP1992625A1
(en)
|
2007-05-16 |
2008-11-19 |
Sanofi-Aventis |
Arylamide pyrimidone compounds
|
EP1992624A1
(en)
|
2007-05-16 |
2008-11-19 |
Sanofi-Aventis |
Heteroarylamide pyrimidone compounds
|
EP1992621A1
(en)
|
2007-05-16 |
2008-11-19 |
Sanofi-Aventis |
Heteroarylamide-substituted pyrimidone derivatives for the treatment of neurodegenerative diseases
|
US8236855B2
(en)
|
2007-05-17 |
2012-08-07 |
Case Western Reserve University |
Methods of treating metabolic disorders
|
KR101376432B1
(ko)
|
2007-05-18 |
2014-05-16 |
시오노기세이야쿠가부시키가이샤 |
11β-하이드록시스테로이드 탈수소효소 유형 1 저해 활성을 갖는 질소-함유 헤테로환형 유도체
|
CN101754972A
(zh)
|
2007-05-18 |
2010-06-23 |
百时美施贵宝公司 |
Sglt2抑制剂的晶体结构及其制备方法
|
US20080306102A1
(en)
|
2007-05-18 |
2008-12-11 |
Kowa Co., Ltd. |
Novel spirooxyindole compounds and drugs containing same
|
US8193187B2
(en)
|
2007-05-29 |
2012-06-05 |
Santen Pharmaceutical Co., Ltd. |
1,2,3,4-tetrahydroquinoxaline compound with a phenyl group substituent having a sulfonic acid ester structure or a sulfonic acid amide structure introduced therein and having glucocorticoid receptor-binding activity
|
US7829664B2
(en)
|
2007-06-01 |
2010-11-09 |
Boehringer Ingelheim International Gmbh |
Modified nucleotide sequence encoding glucagon-like peptide-1 (GLP-1), nucleic acid construct comprising same for production of glucagon-like peptide-1 (GLP-1), human cells comprising said construct and insulin-producing constructs, and methods of use thereof
|
WO2008145721A2
(en)
|
2007-06-01 |
2008-12-04 |
Novo Nordisk A/S |
N-terminal modification of polypeptides for protection against degradation by aminopeptidases
|
AR066820A1
(es)
|
2007-06-04 |
2009-09-16 |
Novartis Ag |
Compuestos de tiadiazolidin-3 ona
|
EP2164519A2
(en)
|
2007-06-08 |
2010-03-24 |
Ascendis Pharma AS |
Long-acting polymeric prodrugs of exendin
|
CN101679365A
(zh)
|
2007-06-08 |
2010-03-24 |
艾德维纳斯医疗私人有限公司 |
作为葡萄糖激酶激活剂的新型吡咯-2-甲酰胺衍生物、它们的制造方法和药学应用
|
EP2170852A1
(en)
|
2007-06-11 |
2010-04-07 |
Bristol-Myers Squibb Company |
1, 3 - dihydroxy substituted phenylamide glucokinase activators
|
EP2158214B1
(en)
|
2007-06-15 |
2011-08-17 |
Zealand Pharma A/S |
Glucagon analogues
|
EP2157859A4
(en)
|
2007-06-19 |
2011-01-12 |
Takeda Pharmaceutical |
INDAZOL COMPOUNDS FOR THE ACTIVATION OF GLUCCOKINASE
|
JPWO2008156174A1
(ja)
|
2007-06-21 |
2010-08-26 |
大正製薬株式会社 |
ピラジンアミド化合物
|
CL2008001839A1
(es)
|
2007-06-21 |
2009-01-16 |
Incyte Holdings Corp |
Compuestos derivados de 2,7-diazaespirociclos, inhibidores de 11-beta hidroxil esteroide deshidrogenasa tipo 1; composicion farmaceutica que comprende a dichos compuestos; utiles para tratar la obesidad, diabetes, intolerancia a la glucosa, diabetes tipo ii, entre otras enfermedades.
|
JP5223864B2
(ja)
|
2007-06-27 |
2013-06-26 |
大正製薬株式会社 |
11β−HSD1阻害活性を有する化合物
|
WO2009000087A1
(en)
|
2007-06-28 |
2008-12-31 |
Merck Frosst Canada Ltd. |
Substituted fused pyrimidines as antagonists of gpr105 activity
|
WO2009005672A1
(en)
|
2007-06-29 |
2009-01-08 |
Merck & Co., Inc. |
Antidiabetic azaindoles and diazaindoles
|
WO2009003681A1
(en)
|
2007-07-02 |
2009-01-08 |
Santhera Pharmaceuticals (Schweiz) Ag |
Dpp-iv inhibitors
|
CN101970475A
(zh)
|
2007-07-09 |
2011-02-09 |
帝国改革有限公司 |
人类胰多肽(hpp)类似物及其对摄食行为的作用
|
DE102007032349A1
(de)
|
2007-07-11 |
2009-01-15 |
Bayer Healthcare Ag |
Imidazo-, Pyrazolopyrazine und Imidazotriazine und ihre Verwendung
|
EP2178821A2
(en)
|
2007-07-12 |
2010-04-28 |
Deviris Inc. |
Hormone sensitive lipase modulators and methods of use
|
WO2009012039A2
(en)
|
2007-07-13 |
2009-01-22 |
Metabasis Therapeutics Inc. |
Crystalline polymorphs
|
PT2173737E
(pt)
|
2007-07-17 |
2012-03-19 |
Bristol Myers Squibb Co |
Método para modular receptor gpr119 acoplado a proteína g e compostos seleccionados
|
EP2178845B1
(en)
|
2007-07-17 |
2013-06-19 |
F. Hoffmann-La Roche AG |
Inhibitors of 11b-hydroxysteroid dehydrogenase
|
US8053574B2
(en)
|
2007-07-18 |
2011-11-08 |
Novartis Ag |
Organic compounds
|
CN101754962B
(zh)
|
2007-07-19 |
2013-12-25 |
赛马拜制药公司 |
作为rup3或gpr119受体的激动剂治疗糖尿病和代谢性病症的n-氮杂环状经取代吡咯、吡唑、咪唑、三唑和四唑衍生物
|
JP5215607B2
(ja)
|
2007-07-23 |
2013-06-19 |
シーシーアイ株式会社 |
ペルオキシゾーム増殖剤応答性受容体(PPAR)αリガンド剤
|
WO2009014676A1
(en)
|
2007-07-23 |
2009-01-29 |
Merck & Co., Inc. |
Novel crystalline form of a dihydrochloride salt of a dipeptidyl peptidase-iv inhibitor
|
US20100317863A1
(en)
|
2007-07-25 |
2010-12-16 |
Boehringer Ingelheim International Gmbh |
Glucocorticoid Mimetics, Methods of Making Them, Pharmaceutical Compositions and Uses Thereof
|
US8759355B2
(en)
|
2007-07-25 |
2014-06-24 |
Institute Of Pharmacology And Toxicology Academy Of Military Medical Sciences P.L.A. |
Aryl pyrimidine derivatives, preparation methods and pharmaceutical uses thereof
|
AR067673A1
(es)
|
2007-07-26 |
2009-10-21 |
Vitae Pharmaceuticals Inc |
Derivados de 1,3 oxazinan - 2 - ona como inhibidores ciclicos de la 11 beta -hidroxiesteroide deshidrogenasa 1. composiciones farmaceuticas.
|
DE102007035334A1
(de)
|
2007-07-27 |
2009-01-29 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue substituierte Arylsulfonylglycine, deren Herstellung und deren Verwendung als Arzneimittel
|
WO2009018065A2
(en)
|
2007-07-27 |
2009-02-05 |
Bristol-Myers Squibb Company |
Novel glucokinase activators and methods of using same
|
DE102007035333A1
(de)
|
2007-07-27 |
2009-01-29 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue substituierte Arylsulfonylglycine, deren Herstellung und deren Verwendung als Arzneimittel
|
US20100267720A1
(en)
|
2007-07-30 |
2010-10-21 |
Astrazeneca Ab |
Crystalline Forms of 2-Hydroxy-3- [5- (Morpholin- 4- Ylmethyl) Pyridin-2-YL] IH- Indole- 5 -Carbonitrile Citrate
|
EP2020232A1
(en)
|
2007-08-03 |
2009-02-04 |
Zeltia, S.A. |
N-(1-thiazolyl)-amide derivatives for the treatment of obesity, diabetes and cardiovascular diseases
|
WO2009019600A2
(en)
|
2007-08-03 |
2009-02-12 |
Dr. Reddy's Laboratories Ltd. |
Modulation of endogenous ampk levels for the treatment of obesity
|
TW200918049A
(en)
|
2007-08-03 |
2009-05-01 |
Betagenon Ab |
Compounds useful as medicaments
|
WO2009020140A1
(ja)
|
2007-08-06 |
2009-02-12 |
Dainippon Sumitomo Pharma Co., Ltd. |
アダマンチルウレア誘導体
|
FR2919869B1
(fr)
|
2007-08-09 |
2009-09-25 |
Sanofi Aventis Sa |
Nouveaux derives de n, n'-2,4-dianilinopyrimidines, leur preparation a titre de medicaments, compositions pharmaceutiques et notamment comme inhibiteurs de ikk
|
CN106279283A
(zh)
|
2007-08-13 |
2017-01-04 |
症变治疗公司 |
新颖的葡糖激酶活化剂
|
CA2696288A1
(en)
|
2007-08-15 |
2009-02-19 |
Schering Corporation |
6-substituted sulfonyl azabicyclo[3.2.1]octanes useful to inhibit 11.beta.-hydroxysteroid dehydrogenase type-1
|
EP2195315B1
(en)
|
2007-08-15 |
2017-01-18 |
Merck Sharp & Dohme Corp. |
Substituted bicyclic piperidinyl-and piperazinyl- sulfonamides useful to inhibit 11 -hydroxysteroid dehydrogenase type-1
|
US20110129542A1
(en)
|
2007-08-15 |
2011-06-02 |
Schering Corporation |
Substituted azepine- and diazepine-sulfonamides useful to inhibit 11beta-hydroxysteroid dehydrogenase type-1
|
WO2009026345A1
(en)
|
2007-08-20 |
2009-02-26 |
Targegen Inc. |
Thiazolidinone compounds, and methods of making and using same
|
AU2008289573B2
(en)
|
2007-08-21 |
2013-05-16 |
Merck Sharp & Dohme Corp. |
Heterocyclic compounds as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes
|
JP5736098B2
(ja)
|
2007-08-21 |
2015-06-17 |
アッヴィ・インコーポレイテッド |
中枢神経系障害を治療するための医薬組成物
|
BRPI0815708B8
(pt)
|
2007-08-23 |
2021-05-25 |
Theracos Sub Llc |
composto, éster de pró-droga, composição farmacêutica, e, método para tratar uma doença ou condição
|
WO2009026657A1
(en)
|
2007-08-29 |
2009-03-05 |
The University Of Sydney |
Flavonoid ppar agonists
|
WO2009026658A1
(en)
|
2007-08-29 |
2009-03-05 |
The University Of Sydney |
Ppar agonists
|
US20090105480A1
(en)
|
2007-08-30 |
2009-04-23 |
Ulrike Bromberger |
Process for the preparation of a dpp-iv inhibitor
|
EP2197858B1
(en)
|
2007-08-31 |
2014-07-02 |
HanAll Biopharma Co., Ltd. |
1,3,5-triazine-2,4,6-triamine compound or pharmaceutical acceptable salt thereof, and pharmaceutical composition comprising the same
|
US20090062369A1
(en)
|
2007-08-31 |
2009-03-05 |
Joaquim Trias |
Use of secretory phospholipase a2 (spla2) inhibitors to decrease spla2 levels
|
ES2532116T3
(es)
|
2007-09-05 |
2015-03-24 |
Novo Nordisk A/S |
Péptidos derivados con A-B-C-D y sus usos terapéuticos
|
DE102007042154A1
(de)
|
2007-09-05 |
2009-03-12 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Arylsulfonylaminomethyphosphonsäure-Derivate, deren Herstellung und deren Verwendung als Arzneimittel
|
WO2009030774A1
(en)
|
2007-09-05 |
2009-03-12 |
Novo Nordisk A/S |
Truncated glp-1 derivatives and their therapeutical use
|
EP2679597A1
(en)
|
2007-09-05 |
2014-01-01 |
Novo Nordisk A/S |
Glucagon-like peptide-1 derivatives and their pharmaceutical use
|
CA2922021C
(en)
|
2007-09-06 |
2018-01-09 |
Ohr Pharmaceutical, Inc. |
A method for treating diabetes
|
US20100256056A1
(en)
|
2007-09-07 |
2010-10-07 |
Zheng Xin Dong |
Analogues of exendin-4 and exendin-3
|
DE102007042754A1
(de)
|
2007-09-07 |
2009-03-12 |
Bayer Healthcare Ag |
Substituierte 6-Phenylnikotinsäuren und ihre Verwendung
|
US20100286112A1
(en)
|
2007-09-10 |
2010-11-11 |
Oscar Barba |
Compounds for the treatment of metabolic disorders
|
AU2008299903B2
(en)
|
2007-09-11 |
2013-08-29 |
Kyorin Pharmaceutical Co., Ltd |
Cyanoaminoquinolones and tetrazoloaminoquinolones as GSK-3 inhibitors
|
EP2036923A1
(en)
|
2007-09-11 |
2009-03-18 |
Novo Nordisk A/S |
Improved derivates of amylin
|
WO2009034117A1
(en)
|
2007-09-11 |
2009-03-19 |
Novo Nordisk A/S |
Mixture comprising an amylin peptide and a protracted insulin
|
KR101597841B1
(ko)
|
2007-09-12 |
2016-02-26 |
교린 세이야꾸 가부시키 가이샤 |
Gsk-3 억제제로서의 스피로시클릭 아미노퀴놀론
|
US7659313B2
(en)
|
2007-09-13 |
2010-02-09 |
Gateway Health Alliances, Inc. |
Methods and related compositions using specific indanes to reduce weight and inhibit lipase, α-amylase and α-glucosidase activity in mammals
|
AU2008301905B2
(en)
|
2007-09-14 |
2013-06-27 |
Cirius Therapeutics, Inc. |
Thiazolidinedione analogues for the treatment of hypertension
|
WO2009038204A1
(ja)
|
2007-09-17 |
2009-03-26 |
Pharma Frontier Co., Ltd. |
新規長鎖脂肪酸誘導体化合物及びそれら化合物を有効成分とするgタンパク質共役型レセプター作動剤
|
WO2009038064A1
(ja)
|
2007-09-19 |
2009-03-26 |
Institute Of Medicinal Molecular Design, Inc. |
I型11βヒドロキシステロイド脱水素酵素阻害活性を有する複素環誘導体
|
MX2010003117A
(es)
|
2007-09-20 |
2010-04-01 |
Irm Llc |
Compuestos y composiciones como moduladores de la actividad de gpr119.
|
KR20090031122A
(ko)
|
2007-09-21 |
2009-03-25 |
주식회사 중외제약 |
인다졸 골격을 함유하는 화합물, 이의 제조방법 및 상기화합물을 함유하는 약제학적 조성물
|
BRPI0817198A2
(pt)
|
2007-09-21 |
2015-03-17 |
Sanofi Aventis |
(ciclopropilfenil)feniloxalamidas, método para a produção das mesmas, e uso das mesmas como um medicamento
|
ATE513830T1
(de)
|
2007-09-21 |
2011-07-15 |
Sanofi Aventis |
Phenothiazin-derivate mit doppelbindung, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
|
WO2009037719A1
(en)
|
2007-09-21 |
2009-03-26 |
Lupin Limited |
Novel compounds as dipeptidyl peptidase iv (dpp iv) inhibitors
|
WO2009039943A1
(de)
|
2007-09-21 |
2009-04-02 |
Sanofi-Aventis |
(carboxylalkylen-phenyl)-phenyl-oxalamide, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
|
US8212045B2
(en)
|
2007-09-21 |
2012-07-03 |
Array Biopharma, Inc. |
Pyridin-2-yl-amino-1, 2, 4-thiadiazole derivatives as glucokinase activators for the treatment of diabetes mellitus
|
US8143280B2
(en)
|
2007-09-27 |
2012-03-27 |
Hoffmann-La Roche Inc. |
Glucocorticoid receptor antagonists
|
CN101932557A
(zh)
|
2007-09-28 |
2010-12-29 |
葛兰素史密丝克莱恩有限责任公司 |
糖原磷酸化酶抑制剂化合物及其药物组合物
|
US20100234433A1
(en)
|
2007-09-28 |
2010-09-16 |
Pierette Banker |
Glycogen phosphorylase inhibitor compound and pharmaceutical composition thereof
|
US8119658B2
(en)
|
2007-10-01 |
2012-02-21 |
Bristol-Myers Squibb Company |
Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors
|
US8501955B2
(en)
|
2007-10-08 |
2013-08-06 |
Advinus Therapeutics Private Limited |
Acetamide derivatives as glucokinase activators, their process and medicinal application
|
DK2197849T3
(da)
|
2007-10-09 |
2013-03-25 |
Merck Patent Gmbh |
N-(pyrazol-3-yl)-benzamidderivater som glucosinaseaktivatorer
|
SI2195312T1
(sl)
|
2007-10-09 |
2013-01-31 |
Merck Patent Gmbh |
Derivati piridina, uporabni kot aktivatorji glukokinaze
|
WO2009047240A1
(en)
|
2007-10-09 |
2009-04-16 |
Smithkline Beecham Corporation |
Indole derivatives useful as ppar activators
|
BRPI0818253A2
(pt)
|
2007-10-10 |
2015-04-07 |
Amgen Inc |
Moduladores de gpr40 bifenil substituídos
|
CN101821243B
(zh)
|
2007-10-11 |
2013-05-08 |
中国科学院上海药物研究所 |
一类嘧啶取代苯丙酸衍生物及其作为ppar激动剂的用途
|
DE102007048716A1
(de)
|
2007-10-11 |
2009-04-23 |
Merck Patent Gmbh |
Imidazo[1,2-a]pyrimidinderivate
|
WO2009049222A1
(en)
|
2007-10-12 |
2009-04-16 |
Curedm, Inc. |
Compositions and methods of using the human proislet peptide receptor
|
GB0720390D0
(en)
|
2007-10-18 |
2007-11-28 |
Prosidion Ltd |
G-Protein coupled receptor agonists
|
GB0720389D0
(en)
|
2007-10-18 |
2008-11-12 |
Prosidion Ltd |
G-Protein Coupled Receptor Agonists
|
JP2011500727A
(ja)
|
2007-10-22 |
2011-01-06 |
シェーリング コーポレイション |
Gpr119の活性のモジュレーターとしての二環式ヘテロ環誘導体およびその使用
|
CN101417999A
(zh)
|
2007-10-25 |
2009-04-29 |
上海恒瑞医药有限公司 |
哌嗪类衍生物,其制备方法及其在医药上的应用
|
BRPI0818687A2
(pt)
|
2007-10-26 |
2017-05-02 |
Japan Tobacco Inc |
composto espiro, o sal deste farmaceuticamente aceitavél ou o solvato deste, composição farmacêutica, medicamento agonista de gpr40, agente promotor da secreção de insulina ou um agente hipoglicêmico, uso do composto espíro, o sal deste farmaceuticamente aceitavél ou o solvato deste, e, métodos para a ativação de gpr40, para promover secreção de insulina ou diminuir o nível de glicose sanguínea, e para tratar ou prevenir uma doença.
|
WO2009056881A1
(en)
|
2007-10-29 |
2009-05-07 |
Astrazeneca Ab |
Chemical compounds 313
|
AU2008319418B2
(en)
|
2007-10-29 |
2013-08-15 |
Merck Sharp & Dohme Corp. |
Antidiabetic tricyclic compounds
|
JP5771005B2
(ja)
|
2007-10-30 |
2015-08-26 |
インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation |
グルカゴンアンタゴニスト及びglp−1アゴニスト活性を示す化合物
|
JP5669582B2
(ja)
|
2007-10-30 |
2015-02-12 |
インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation |
グルカゴンアンタゴニスト
|
WO2009057784A1
(ja)
|
2007-11-01 |
2009-05-07 |
Takeda Pharmaceutical Company Limited |
複素環化合物
|
UA102379C2
(ru)
|
2007-11-05 |
2013-07-10 |
Мерк Патент Гмбх |
Производные 7-азаиндола как селективные ингибиторы бета-гидроксистероида дегидрогеназы 1 типа
|
AR069207A1
(es)
|
2007-11-07 |
2010-01-06 |
Vitae Pharmaceuticals Inc |
Ureas ciclicas como inhibidores de la 11 beta - hidroxi-esteroide deshidrogenasa 1
|
CN101932601B
(zh)
|
2007-11-08 |
2016-08-03 |
诺沃-诺迪斯克有限公司 |
胰岛素衍生物
|
ES2493593T3
(es)
|
2007-11-12 |
2014-09-12 |
Msd K.K. |
Derivado de heteroariloxi quinazolina
|
EP2058308A1
(fr)
|
2007-11-12 |
2009-05-13 |
Merck Sante |
Dérivés de benzimidazoledihydrothiadiazinone comme inhibiteurs de fructose-1,6-biphosphatase et compositions pharmaceutiques les contenant.
|
AR069545A1
(es)
|
2007-11-16 |
2010-02-03 |
Boehringer Ingelheim Pharma |
Derivados de aril y heteroarilcarbonilo de benzomorfanos y estructuras relacionadas, composiciones farmaceuticas que contienen dichos compuestos, obtencion de las mismas, su uso en el tratamiento de enfermedades mediadas por la inhibicion de la enzima 11beta-hidroxiesteroide deshidrogenasa (hsd) 1 y
|
ES2552733T3
(es)
|
2007-11-16 |
2015-12-01 |
Rigel Pharmaceuticals, Inc. |
Compuestos de carboxamida, sulfonamida y amina para trastornos metabólicos
|
US20090221595A1
(en)
|
2007-11-26 |
2009-09-03 |
Nurit Perlman |
Crystalline form of sitagliptin
|
WO2009070497A1
(en)
|
2007-11-28 |
2009-06-04 |
Smithkline Beecham Corporation |
SEH AND 11 β-HSD1 INHIBITORS AND THEIR USE
|
WO2009069736A1
(ja)
|
2007-11-28 |
2009-06-04 |
Kyowa Hakko Kirin Co., Ltd. |
含窒素化合物
|
US7973051B2
(en)
|
2007-11-30 |
2011-07-05 |
Hoffman-La Roche Inc. |
Aminothiazoles as FBPase inhibitors for diabetes
|
JP5401465B2
(ja)
|
2007-11-30 |
2014-01-29 |
ノバルティス アーゲー |
有機化合物
|
JP2011504898A
(ja)
|
2007-11-30 |
2011-02-17 |
エフ.ホフマン−ラ ロシュ アーゲー |
ピリジン化合物
|
CN101450963B
(zh)
|
2007-11-30 |
2012-03-14 |
中国科学院上海药物研究所 |
葫芦烷型三萜皂苷化合物、其药物组合物及其制备方法和用途
|
WO2009071890A1
(en)
|
2007-12-04 |
2009-06-11 |
Ucb Pharma S.A. |
Tricyclic kinase inhibitors
|
WO2009071895A1
(en)
|
2007-12-04 |
2009-06-11 |
Ucb Pharma S.A. |
Fused thiazole and thiophene derivatives as kinase inhibitors
|
AU2008331417A1
(en)
|
2007-12-04 |
2009-06-11 |
Merck Frosst Canada Ltd |
Substituted 2-naphthoic acids as antagonists of GPR105 activity
|
GB0723747D0
(en)
|
2007-12-04 |
2008-12-31 |
Ucb Pharma Sa |
Therapeutic agents
|
WO2009072581A1
(ja)
|
2007-12-05 |
2009-06-11 |
Aska Pharmaceutical Co., Ltd. |
ラクタム化合物又はその塩及びppar活性化剤
|
ES2382579T3
(es)
|
2007-12-11 |
2012-06-11 |
Cadila Healthcare Limited |
Peptidomiméticos con actividad antagonista de glucagón y agonista de GLP-1
|
US8440658B2
(en)
|
2007-12-11 |
2013-05-14 |
Vitae Pharmaceuticals, Inc. |
Cyclic urea inhibitors of 11β-hydroxysteroid dehydrogenase 1
|
JP2011032169A
(ja)
|
2007-12-11 |
2011-02-17 |
Genecare Research Institute Co Ltd |
4−アミノピリミジン誘導体および該化合物を含有する医薬組成物
|
GB0724251D0
(en)
|
2007-12-12 |
2008-02-06 |
Univ Edinburgh |
Therapeutic compounds and their use
|
JP5650540B2
(ja)
|
2007-12-12 |
2015-01-07 |
ライジェル ファーマシューティカルズ, インコーポレイテッド |
代謝障害のためのカルボキサミド、スルホンアミド、およびアミン化合物
|
UA101004C2
(en)
|
2007-12-13 |
2013-02-25 |
Теракос, Инк. |
Derivatives of benzylphenylcyclohexane and use thereof
|
WO2009080024A1
(en)
|
2007-12-20 |
2009-07-02 |
Fertin Pharma A/S |
Compressed chewing gum comprising an incretin mimetic
|
DE102007061757A1
(de)
|
2007-12-20 |
2009-06-25 |
Bayer Healthcare Ag |
Substituierte 2-Phenylpyrimidin-5-carbonsäuren und ihre Verwendung
|
DE102007061756A1
(de)
|
2007-12-20 |
2009-06-25 |
Bayer Healthcare Ag |
Substituierte 4-Aminopyrimidin-5-carbonsäuren und ihre Verwendung
|
WO2009080032A1
(en)
|
2007-12-20 |
2009-07-02 |
Fertin Pharma A/S |
Compressed chewing gum comprising a systemically active small peptide
|
WO2009082152A2
(en)
|
2007-12-20 |
2009-07-02 |
Lg Life Sciences Ltd. |
Glucokinase activators and pharmaceutical compositions containing the same as an active ingredient
|
AU2008341352B2
(en)
|
2007-12-21 |
2013-08-01 |
Lg Chem, Ltd. |
Dipeptidyl peptidase-IV inhibiting compounds, methods of preparing the same, and pharmaceutical compositions containing the same as active agent
|
IE20070928A1
(en)
|
2007-12-21 |
2009-09-30 |
Giuliani Int Ltd |
Multi target ligands
|
JPWO2009081782A1
(ja)
|
2007-12-25 |
2011-05-06 |
萬有製薬株式会社 |
N−ピラゾール−2−ピリジンカルボキサミド誘導体
|
MX2010006647A
(es)
|
2007-12-26 |
2010-08-17 |
Sanofi Aventis |
Piridil-n-[1,3,4]-tiadiazol-2-il-bencenosulfonamidas ciclicas, procedimientos para su preparacion y su uso como productos farmaceuticos.
|
CN101468988A
(zh)
|
2007-12-26 |
2009-07-01 |
上海恒瑞医药有限公司 |
哌嗪类衍生物,其制备方法及其在医药上的应用
|
US8399418B2
(en)
|
2007-12-27 |
2013-03-19 |
Kissei Pharmaceutical Co., Ltd. |
Monosebacate of pyrazole derivative
|
TW200938200A
(en)
|
2007-12-28 |
2009-09-16 |
Dainippon Sumitomo Pharma Co |
Methyl-substituted piperidine derivative
|
WO2009083553A1
(en)
|
2007-12-31 |
2009-07-09 |
Rheoscience A/S |
Azine compounds as glucokinase activators
|
GB0800035D0
(en)
|
2008-01-02 |
2008-02-13 |
Glaxo Group Ltd |
Compounds
|
TW200934490A
(en)
|
2008-01-07 |
2009-08-16 |
Vitae Pharmaceuticals Inc |
Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
|
US20090270418A1
(en)
|
2008-01-09 |
2009-10-29 |
Marianne Sloss |
Pyrazole pyrazine amine compounds as kinase inhibitors, compositions thereof and methods of treatment therewith
|
GB0800383D0
(en)
|
2008-01-10 |
2008-02-20 |
Univ Strathclyde |
Weight reducing compounds
|
JP2011509289A
(ja)
|
2008-01-10 |
2011-03-24 |
サン・ファーマ・アドバンスド・リサーチ・カンパニー・リミテッド |
新規なアシルシアノピロリジン誘導体
|
PE20091313A1
(es)
|
2008-01-15 |
2009-09-03 |
Lilly Co Eli |
(r)-2-(4-ciclopropansulfonil-fenil)-n-pirazin-2-il-3-(tetrahidropiran-4-il)-propionamida cristalina
|
US20100022590A1
(en)
|
2008-01-17 |
2010-01-28 |
Biovitrum Ab (Publ.) |
Novel compounds
|
CL2008003653A1
(es)
|
2008-01-17 |
2010-03-05 |
Mitsubishi Tanabe Pharma Corp |
Uso de un inhibidor de sglt derivado de glucopiranosilo y un inhibidor de dppiv seleccionado para tratar la diabetes; y composicion farmaceutica.
|
RU2010134411A
(ru)
|
2008-01-18 |
2012-02-27 |
Астеллас Фарма Инк. (Jp) |
Фенилацетамидное производное
|
EP2250157B1
(en)
|
2008-01-24 |
2014-11-05 |
Panacea Biotec Limited |
Novel heterocyclic compounds
|
US20090238879A1
(en)
|
2008-01-24 |
2009-09-24 |
Northwestern University |
Delivery scaffolds and related methods of use
|
WO2009094169A1
(en)
|
2008-01-24 |
2009-07-30 |
Vitae Pharmaceuticals, Inc. |
Cyclic carbazate and semicarbazide inhibitors of 11beta-hydroxysteroid dehydrogenase 1
|
MX2010007926A
(es)
|
2008-01-24 |
2010-08-09 |
Merck Patent Gmbh |
Derivados de beta-aminoacidos.
|
TW200936136A
(en)
|
2008-01-28 |
2009-09-01 |
Sanofi Aventis |
Tetrahydroquinoxaline urea derivatives, their preparation and their therapeutic application
|
EP2085400A1
(en)
|
2008-01-29 |
2009-08-05 |
Sanofi-Aventis |
Substituted heteroarylamide oxazepinopyrimidone derivatives
|
EP2090579A1
(en)
|
2008-01-29 |
2009-08-19 |
Sanofi-Aventis |
Substituted heteroarylamide diazepinopyrimidone derivatives
|
EP2085399A1
(en)
|
2008-01-29 |
2009-08-05 |
Sanofi-Aventis |
substituted arylamide oxazepinopyrimidone derivatives
|
EP2090578A1
(en)
|
2008-01-29 |
2009-08-19 |
Sanofi-Aventis |
Substituted arylamide diazepinopyrimidone derivatives for the treatment of neurodegenerative diseases caused by abnormal activity of GSK3-beta
|
WO2009096503A1
(ja)
|
2008-01-31 |
2009-08-06 |
Daiichi Sankyo Company, Limited |
ベンジルフェニルグルコピラノシド誘導体
|
JP5525456B2
(ja)
|
2008-02-04 |
2014-06-18 |
マーキュリー セラピューティクス,インコーポレイテッド |
Ampk調節因子
|
AU2009211215B2
(en)
|
2008-02-04 |
2011-11-03 |
Astrazeneca Ab |
Novel crystalline forms of 4- [4- (2-adamantylcarbam0yl) -5-tert-butyl-pyrazol-1-yl] benzoic acid
|
CA2715143C
(en)
|
2008-02-06 |
2013-04-02 |
Daiichi Sankyo Company, Limited |
Novel phenylpyrrole derivative
|
WO2009099171A1
(ja)
|
2008-02-07 |
2009-08-13 |
Takeda Pharmaceutical Company Limited |
医薬
|
WO2009099172A1
(ja)
|
2008-02-07 |
2009-08-13 |
Takeda Pharmaceutical Company Limited |
医薬
|
JP5734666B2
(ja)
|
2008-02-11 |
2015-06-17 |
ヴァイティー ファーマシューティカルズ,インコーポレイテッド |
11β−ヒドロキシステロイドデヒドロゲナーゼ1の1,3−オキサアゼパン−2−オン及び1,3−ジアゼパン−2−オン阻害剤
|
US20110028445A1
(en)
|
2008-02-12 |
2011-02-03 |
Boehringer Ingelheim International Gmbh |
Urea derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
|
PL384446A1
(pl)
|
2008-02-12 |
2009-08-17 |
Adamed Spółka Z Ograniczoną Odpowiedzialnością |
Sól 5-[[4-[2-(metylo-2-pirydynyloamino)etoksy]fenylo]metylo]-2,4-tiazolidynodionu z kwasem malonowym i sposób jej wytwarzania
|
US8263630B2
(en)
|
2008-02-12 |
2012-09-11 |
Bristol-Myers Squibb Company |
1,2,3-triazoles as 11-beta hydroxysteroid dehydrogenase type I inhibitors
|
CL2009000309A1
(es)
|
2008-02-13 |
2009-06-26 |
Sanofi Aventis |
Derivados fluoroglicosidos aromaticos, composicion farmaceutica que contenga estos compuestos, procedimiento para prepararla y su uso en el tratamiento de la diabetes tipo 1 y 2.
|
JP5730021B2
(ja)
|
2008-02-15 |
2015-06-03 |
ヴァイティー ファーマシューティカルズ,インコーポレイテッド |
11β−ヒドロキシステロイドデヒドロゲナーゼ1の阻害剤としてのシクロアルキルラクタム誘導体
|
BRPI0907584A2
(pt)
|
2008-02-22 |
2015-07-21 |
Irm Llc |
Composto e composições como moduladores de atividade de gpr119
|
EA201001330A1
(ru)
|
2008-02-22 |
2011-04-29 |
Айрм Ллк |
Соединения и композиции в качестве модуляторов активности gpr119
|
JP2011513233A
(ja)
|
2008-02-22 |
2011-04-28 |
アイアールエム・リミテッド・ライアビリティ・カンパニー |
Gpr119活性モジュレーターとしての化合物および組成物
|
EP2244706B1
(en)
|
2008-02-25 |
2016-04-06 |
Merck Patent GmbH |
Glucokinase activators
|
KR100864584B1
(ko)
|
2008-02-25 |
2008-10-24 |
성균관대학교산학협력단 |
비오틴으로 수식된 엑센딘 유도체, 이의 제조방법 및 이의용도
|
GB0803494D0
(en)
|
2008-02-26 |
2008-04-02 |
Sterix Ltd |
Compound
|
US8383629B2
(en)
|
2008-02-27 |
2013-02-26 |
Vitae Pharmaceuticals, Inc. |
Inhibitors of 11β-hydroxysteroid dehydrogenase type 1
|
WO2009106565A1
(en)
|
2008-02-27 |
2009-09-03 |
Biovitrum Ab (Publ) |
Agonists of gpr119
|
WO2009106561A1
(en)
|
2008-02-27 |
2009-09-03 |
Biovitrum Ab (Publ) |
Pyrazine compounds for treating gpr119 related disorders
|
JP2011513253A
(ja)
|
2008-02-27 |
2011-04-28 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング |
糖尿病を治療するためのカルボキサミド−ヘテロアリール誘導体
|
FR2928149B1
(fr)
|
2008-02-29 |
2011-01-14 |
Sanofi Aventis |
Composes derives d'azetidines, leur preparation et leur application en therapeutique
|
MX2010009536A
(es)
|
2008-03-01 |
2010-09-24 |
Merck Patent Gmbh |
Amidas de acido 5-oxo-2,3,4,5-tetrahidro-benzo[b]oxepin-4-carboxil ico y amidas de acido 2,3-dihidro-benzo[b]oxepin-4-carboxilico para el tratamiento y la prevension de la diabetes tipo 1 y 2.
|
WO2009109998A1
(en)
|
2008-03-03 |
2009-09-11 |
Lupin Limited |
Novel protein tyrosine phosphatase - ib inhibitors
|
WO2009109999A1
(en)
|
2008-03-03 |
2009-09-11 |
Lupin Limited |
Novel protein tyrosine phosphatase - ib inhibitors
|
CN101945858B
(zh)
|
2008-03-05 |
2014-05-21 |
默克专利有限公司 |
作为胰岛素分泌刺激剂的吡嗪酮类衍生物、获得它们的方法及其在治疗糖尿病中的用途
|
CN101970402B
(zh)
|
2008-03-05 |
2013-12-18 |
财团法人国家卫生研究院 |
吡咯烷化合物
|
EA019752B1
(ru)
|
2008-03-05 |
2014-06-30 |
Такеда Фармасьютикал Компани Лимитед |
Гетероциклическое амидное соединение и его применение для лечения/профилактики диабета
|
CA2718402C
(en)
|
2008-03-05 |
2017-08-22 |
Merck Patent Gmbh |
Pyridopyrazinones derivatives insulin secretion stimulators, methods for obtaining them and use thereof for the treatment of diabetes
|
JP2011515341A
(ja)
|
2008-03-06 |
2011-05-19 |
アムジエン・インコーポレーテツド |
代謝障害の治療に有用な立体配座的に制限されたカルボン酸誘導体
|
NZ587343A
(en)
|
2008-03-07 |
2012-05-25 |
Transtech Pharma Inc |
Oxadiazoanthracene compounds for the treatment of diabetes
|
JP2011513483A
(ja)
|
2008-03-10 |
2011-04-28 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
タンパク質キナーゼの阻害剤として有用なピリミジンおよびピリジン
|
EP2264034A1
(en)
|
2008-03-10 |
2010-12-22 |
Dainippon Sumitomo Pharma Co., Ltd. |
Bicyclic pyrrole compound
|
GB0804685D0
(en)
|
2008-03-13 |
2008-04-16 |
Univ Edinburgh |
Therapeutic compounds and their use
|
EP2280966A1
(en)
|
2008-03-14 |
2011-02-09 |
Exelixis, Inc. |
Azabicyclo [3.2.1]octyl derivatives as 11 beta-hsd1 modulators
|
WO2009117421A2
(en)
|
2008-03-17 |
2009-09-24 |
Kalypsys, Inc. |
Heterocyclic modulators of gpr119 for treatment of disease
|
CA2718264A1
(en)
|
2008-03-18 |
2009-09-24 |
Vitae Pharmaceuticals, Inc. |
Inhibitors of 11beta-hydroxysteroid dehydrogenase type 1
|
FR2928836B1
(fr)
|
2008-03-21 |
2011-08-26 |
Servier Lab |
Forme galenique secable permettant une liberation modifiee du principe actif
|
PE20091674A1
(es)
|
2008-03-27 |
2009-11-04 |
Lilly Co Eli |
Antagonistas del receptor de glucagon
|
US20090247532A1
(en)
|
2008-03-28 |
2009-10-01 |
Mae De Ltd. |
Crystalline polymorph of sitagliptin phosphate and its preparation
|
DK2280704T3
(en)
|
2008-03-31 |
2015-06-29 |
Cymabay Therapeutics Inc |
Oxymethylenarylforbindelser and uses thereof
|
EP2262539B1
(en)
|
2008-04-01 |
2015-07-15 |
Novo Nordisk A/S |
Insulin albumin conjugates
|
FR2929615B1
(fr)
|
2008-04-02 |
2010-12-17 |
Tfchem |
Composes c-aryl glycosides pour le traitement du diabete et de l'obesite.
|
PE20091730A1
(es)
|
2008-04-03 |
2009-12-10 |
Boehringer Ingelheim Int |
Formulaciones que comprenden un inhibidor de dpp4
|
WO2009125434A2
(en)
|
2008-04-07 |
2009-10-15 |
Cadila Healthcare Limited |
Oxime derivatives
|
DE102008017590A1
(de)
|
2008-04-07 |
2009-10-08 |
Merck Patent Gmbh |
Glucopyranosidderivate
|
EP2271619A1
(en)
|
2008-04-07 |
2011-01-12 |
Irm Llc |
Compounds and compositions as modulators of gpr119 activity
|
MX2010011138A
(es)
|
2008-04-10 |
2010-11-12 |
Takeda Pharmaceutical |
Compuestos de anillo fusionados y uso de los mismos.
|
MX2010011047A
(es)
|
2008-04-11 |
2010-10-26 |
Merck Patent Gmbh |
Derivados de tienopiridonas como activadores de proteina cinasa activada por amp (ampk).
|
WO2009129036A1
(en)
|
2008-04-14 |
2009-10-22 |
Merck & Co., Inc. |
Substituted cyclopropyl compounds, compositions containing such compounds and methods of treatment
|
WO2009128558A1
(ja)
|
2008-04-15 |
2009-10-22 |
日本ケミファ株式会社 |
ペルオキシソーム増殖剤活性化受容体の活性化剤
|
CN102007138B
(zh)
|
2008-04-16 |
2014-05-21 |
橘生药品工业株式会社 |
吡唑衍生物的半富马酸盐
|
US8258134B2
(en)
|
2008-04-16 |
2012-09-04 |
Hoffmann-La Roche Inc. |
Pyridazinone glucokinase activators
|
US7741327B2
(en)
|
2008-04-16 |
2010-06-22 |
Hoffmann-La Roche Inc. |
Pyrrolidinone glucokinase activators
|
EP2266983B1
(en)
|
2008-04-16 |
2013-06-05 |
Takeda Pharmaceutical Company Limited |
Nitrogenated 5-membered heterocyclic compound
|
DE102008019838A1
(de)
|
2008-04-19 |
2009-12-10 |
Boehringer Ingelheim International Gmbh |
Neue Arylsulfonylglycin-Derivate, deren Herstellung und deren Verwendung als Arzneimittel
|
TW200944526A
(en)
|
2008-04-22 |
2009-11-01 |
Vitae Pharmaceuticals Inc |
Carbamate and urea inhibitors of 11β-hydroxysteroid dehydrogenase 1
|
KR20110002475A
(ko)
|
2008-04-22 |
2011-01-07 |
아스트라제네카 아베 |
치환 피리미딘-5-카르복시아미드 281
|
CN101565408A
(zh)
|
2008-04-25 |
2009-10-28 |
国家新药筛选中心 |
一类受体信号转导增效剂,其制备方法和用途
|
WO2009133099A2
(en)
|
2008-04-28 |
2009-11-05 |
Novo Nordisk A/S |
Insulin precursors for diabetes treatment
|
CA2722733C
(en)
|
2008-04-28 |
2016-02-23 |
Kyorin Pharmaceutical Co., Ltd. |
Cyclopentylacrylamide derivative
|
US8124636B2
(en)
|
2008-04-30 |
2012-02-28 |
Hoffmann-La Roche Inc. |
Imidazolidinone derivatives as 11B-HSD1 inhibitors
|
EP2291373B1
(en)
|
2008-05-01 |
2013-09-11 |
Vitae Pharmaceuticals, Inc. |
Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
|
ES2421537T3
(es)
|
2008-05-01 |
2013-09-03 |
Vitae Pharmaceuticals Inc |
Inhibidores cíclicos de la 11beta-hidroxiesteroide deshidrogenasa 1
|
CA2723034A1
(en)
|
2008-05-01 |
2009-11-05 |
Vitae Pharmaceuticals, Inc. |
Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
|
US8569292B2
(en)
|
2008-05-01 |
2013-10-29 |
Vitae Pharmaceuticals, Inc. |
Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1
|
ES2432383T3
(es)
|
2008-05-05 |
2013-12-03 |
Merck Patent Gmbh |
Derivados de nip-tiazol como inhibidores de la 11-beta-hidroxiesteroide deshidrogenasa
|
MX2010011916A
(es)
|
2008-05-05 |
2010-11-26 |
Merck Patent Gmbh |
Derivados de tienopiridonas como activadores de proteinas cinasa activados por amp (ampk).
|
ITMI20080846A1
(it)
|
2008-05-09 |
2009-11-10 |
Andrea Balsari |
Composti a struttura glicosidica attivi nella terapia di stati infiammatori locali e sistemici
|
WO2009139340A1
(ja)
|
2008-05-12 |
2009-11-19 |
武田薬品工業株式会社 |
ピラゾール化合物
|
AR071719A1
(es)
|
2008-05-13 |
2010-07-07 |
Boehringer Ingelheim Int |
Derivados aliciclicos de acido carboxilico de benzomorfanos y estructuras relacionadas, medicamentos que contienen dichos compuestos y su uso.procesos de obtencion
|
DK2275108T3
(da)
|
2008-05-14 |
2014-09-08 |
Sanwa Kagaku Kenkyusho Co |
Farmaceutisk præparat omfattende en dpp-iv-inhibitor og et andet diabetes-terapimiddel i konkomitant eller kombineret form
|
NZ589084A
(en)
|
2008-05-16 |
2012-06-29 |
Takeda San Diego Inc |
Glucokinase activators
|
AU2009246424A1
(en)
|
2008-05-16 |
2009-11-19 |
Schering Corporation |
Glucagon receptor antagonists, compositions, and methods for their use
|
US8188098B2
(en)
|
2008-05-19 |
2012-05-29 |
Hoffmann-La Roche Inc. |
GPR119 receptor agonists
|
AU2009249237A1
(en)
|
2008-05-19 |
2009-11-26 |
Schering Corporation |
Bicyclic heterocycle derivatives and use thereof as GPR119 modulators
|
US20090291982A1
(en)
|
2008-05-22 |
2009-11-26 |
Astrazeneca Ab |
New Substituted Oxindole Derivative 352
|
EP2310371B1
(fr)
|
2008-05-26 |
2013-05-15 |
Genfit |
Composés agonistes ppar, préparation et utilisations pour le traitement du diabète et/ou des dyslipidémies
|
WO2009154697A2
(en)
|
2008-05-28 |
2009-12-23 |
Massachusetts Institute Of Technology |
Disc-1 pathway activators in the control of neurogenesis
|
WO2009147121A1
(en)
|
2008-06-02 |
2009-12-10 |
Smithkline Beecham Corporation |
Carboxyl substituted indoles for use as ppar alpha modulators
|
AU2009255183A1
(en)
|
2008-06-02 |
2009-12-10 |
Msd K.K. |
Novel isoxazole derivative
|
WO2009149056A2
(en)
|
2008-06-02 |
2009-12-10 |
Dr. Reddy's Laboratories Ltd. |
Combinations of niacin and an oxicam
|
CA2726903A1
(en)
|
2008-06-03 |
2009-12-10 |
Trustees Of Tufts College |
Long-acting glp-1 derivatives, and methods of treating cardiac dysfunction
|
JOP20190083A1
(ar)
|
2008-06-04 |
2017-06-16 |
Amgen Inc |
بولي ببتيدات اندماجية طافرة لـfgf21 واستخداماتها
|
MX2010013095A
(es)
|
2008-06-06 |
2010-12-21 |
Boehringer Ingelheim Int |
Mimeticos de glucocorticoides, metodos para su fabricacion, composiciones farmaceuticas y usos de los mismos.
|
WO2010000353A1
(en)
|
2008-06-09 |
2010-01-07 |
Sanofi-Aventis |
Sulfonamides with heterocycle and oxadiazolone headgroup, processes for their preparation and their use as pharmaceuticals
|
WO2009149819A1
(en)
|
2008-06-09 |
2009-12-17 |
Sanofi-Aventis |
Annelated pyrrolidin sulfonamides with oxadiazolone headgroup, processes for their preparation and their use as pharmaceuticals
|
CN102056921A
(zh)
|
2008-06-09 |
2011-05-11 |
赛诺菲-安万特 |
首基为噁二唑酮的增环化n-杂环磺酰胺、其制备方法及其作为药物的用途
|
WO2009150144A1
(en)
|
2008-06-10 |
2009-12-17 |
Inovacia Ab |
New gpr119modulators
|
US8329698B2
(en)
|
2008-06-16 |
2012-12-11 |
MERCK Patent Gesellschaft mit beschränkter Haftung |
Quinoxalinedione derivatives which are activators of AMPK-activated protein kinase
|
US8765669B2
(en)
|
2008-06-17 |
2014-07-01 |
Glytech, Inc. |
Glycosylated GLP-1 peptide
|
JP5753779B2
(ja)
|
2008-06-17 |
2015-07-22 |
インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation |
生理学的pHの緩衝液中で向上した溶解性及び安定性を示すグルカゴン類縁体
|
EA019203B9
(ru)
|
2008-06-17 |
2014-03-31 |
Индиана Юниверсити Рисерч Энд Текнолоджи Корпорейшн |
Коагонисты глюкагонового рецептора/glp-1-рецептора
|
EP2303859A4
(en)
|
2008-06-20 |
2012-08-22 |
Metabolex Inc |
ARYL GPR119 AGONISTS AND USES THEREOF
|
BRPI0914629A2
(pt)
|
2008-06-24 |
2019-09-24 |
Irm Llc |
compostos e métodos para a modulação de receptores acoplados à proteína g
|
EP2138498A1
(en)
|
2008-06-26 |
2009-12-30 |
sanofi-aventis |
Substituted tricyclic derivatives against neurodegenerative diseases
|
EP2138485A1
(en)
|
2008-06-26 |
2009-12-30 |
sanofi-aventis |
Substituted N-Oxide pyrazine derivatives
|
EP2138493A1
(en)
|
2008-06-26 |
2009-12-30 |
Sanofi-Aventis |
Substituted pyrimidone derivatives
|
EP2138488A1
(en)
|
2008-06-26 |
2009-12-30 |
sanofi-aventis |
4-(pyridin-4-yl)-1H-[1,3,5]triazin-2-one derivatives as GSK3-beta inhibitors for the treatment of neurodegenerative diseases
|
EP2138495A1
(en)
|
2008-06-26 |
2009-12-30 |
sanofi-aventis |
Substituted pyrimido[2,1-a]isoquinolin-4-one derivatives
|
EP2138494A1
(en)
|
2008-06-26 |
2009-12-30 |
Sanofi-Aventis |
Substituted alkyl pyrimidin-4-one derivatives
|
EP2138492A1
(en)
|
2008-06-26 |
2009-12-30 |
Sanofi-Aventis |
Substituted pyrimidin-4-one derivatives
|
GB0812031D0
(en)
|
2008-07-01 |
2008-08-06 |
7Tm Pharma As |
Thiazole derivatives
|
EP2318411A2
(en)
|
2008-07-03 |
2011-05-11 |
Ratiopharm GmbH |
Crystalline salts of sitagliptin
|
WO2010006214A1
(en)
|
2008-07-09 |
2010-01-14 |
Ambrx, Inc. |
Fgf-21 neutralizing antibodies and their uses
|
GB0812649D0
(en)
|
2008-07-10 |
2008-08-20 |
Prosidion Ltd |
Compounds
|
EP2321308B9
(en)
|
2008-07-10 |
2012-08-08 |
Prosidion Limited |
Piperidine gpcr agonists
|
GB0812641D0
(en)
|
2008-07-10 |
2008-08-20 |
Prosidion Ltd |
Compounds
|
GB0812648D0
(en)
|
2008-07-10 |
2008-08-20 |
Prosidion Ltd |
Compounds
|
KR20110036609A
(ko)
|
2008-07-10 |
2011-04-07 |
프로시디온 리미티드 |
피페리디닐 gpcr 작용제
|
GB0812642D0
(en)
|
2008-07-10 |
2008-08-20 |
Prosidion Ltd |
Compounds
|
ES2429129T3
(es)
|
2008-07-11 |
2013-11-13 |
Irm Llc |
4-Fenoximetilpiperidinas como moduladores de la actividad de GPR119
|
EP2147910A1
(en)
|
2008-07-15 |
2010-01-27 |
Pronova BioPharma Norge AS |
Novel lipid compounds
|
US8501940B2
(en)
|
2008-07-15 |
2013-08-06 |
Hoffmann-La Roche Inc. |
Tetrahydrocinnoline derivatives
|
TW201006821A
(en)
|
2008-07-16 |
2010-02-16 |
Bristol Myers Squibb Co |
Pyridone and pyridazone analogues as GPR119 modulators
|
AU2009270971A1
(en)
|
2008-07-16 |
2010-01-21 |
Schering Corporation |
Bicyclic Heterocycle Derivatives and use thereof as GPR119 modulators
|
CA2730610A1
(en)
|
2008-07-16 |
2010-01-21 |
Schering Corporation |
Bicyclic heterocycle derivatives and their use as gpcr modulators
|
US8815876B2
(en)
|
2008-07-16 |
2014-08-26 |
Merck Sharp & Dohme Corp. |
Bicyclic heterocycle derivatives and methods of use thereof
|
TWI472521B
(zh)
|
2008-07-17 |
2015-02-11 |
Lexicon Pharmaceuticals Inc |
(2s,3r,4r,5s,6r)-2-(4-氯-3-(4-乙氧苄基)苯基)-6-(甲硫)四氫-2h-哌喃-3,4,5-三醇的固體形態與其使用方法
|
US8846668B2
(en)
|
2008-07-25 |
2014-09-30 |
Vitae Pharmaceuticals, Inc. |
Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
|
WO2010011917A1
(en)
|
2008-07-25 |
2010-01-28 |
Glaxosmithkline Llc |
SEH AND 11β-HSD1 DUAL INHIBITORS
|
EP2318355B1
(en)
|
2008-07-25 |
2018-09-12 |
Boehringer Ingelheim International GmbH |
1,1'-diadamantyl carboxylic acids, medicaments containing such compounds and their use
|
CN102137836B
(zh)
|
2008-07-28 |
2015-08-26 |
赛丹思科大学 |
用于治疗代谢疾病的化合物
|
CN102159215B
(zh)
|
2008-07-28 |
2013-07-17 |
爱默蕾大学 |
使用TrkB激动剂治疗各种病症
|
CA2729581A1
(en)
|
2008-07-29 |
2010-02-04 |
Pfizer Inc. |
Fluorinated heteroaryls
|
AU2009276548A1
(en)
|
2008-07-30 |
2010-02-04 |
Oncotherapy Science, Inc. |
Benzoimidazole derivatives and glycogen synthase kinase-3 beta inhibitors containing the same
|
WO2010014593A1
(en)
|
2008-07-30 |
2010-02-04 |
Smithkline Beecham Corporation |
Chemical compounds and uses
|
ATE529402T1
(de)
|
2008-08-01 |
2011-11-15 |
Centre Nat Rech Scient |
3',6-substituierte indirubine und ihre biologischen anwendungen
|
WO2010014771A1
(en)
|
2008-08-01 |
2010-02-04 |
Ore Pharmaceuticals Inc. |
Romazarit for treating metabolic diseases
|
EP2324028A2
(en)
|
2008-08-04 |
2011-05-25 |
AstraZeneca AB |
Therapeutic agents 414
|
UY32030A
(es)
|
2008-08-06 |
2010-03-26 |
Boehringer Ingelheim Int |
"tratamiento para diabetes en pacientes inapropiados para terapia con metformina"
|
KR20110043686A
(ko)
|
2008-08-07 |
2011-04-27 |
입센 파마 에스.에이.에스 |
포도당 의존적인 인슐린 분비 자극성 폴리펩타이드의 유사체
|
KR101593158B1
(ko)
|
2008-08-07 |
2016-02-12 |
입센 파마 에스.에이.에스. |
N-말단이 변형된 포도당 의존적인 인슐린 분비 자극성 폴리펩타이드(gip)의 유사체
|
KR20130133104A
(ko)
|
2008-08-07 |
2013-12-05 |
입센 파마 에스.에이.에스 |
포도당 의존적인 인슐린 분비 자극성 폴리펩타이드 유사체
|
WO2010016936A1
(en)
|
2008-08-07 |
2010-02-11 |
Ipsen Pharma S.A.S. |
Pharmaceutical compositions of analogues of glucose-dependent insulinotropic polypeptide
|
JP2011530506A
(ja)
|
2008-08-07 |
2011-12-22 |
イプセン ファルマ ソシエテ パール アクシオン サンプリフィエ |
グルコース依存性インスリン分泌刺激ポリペプチドの切り詰められたアナログ
|
WO2010018435A1
(en)
|
2008-08-11 |
2010-02-18 |
Hetero Research Foundation |
Amide glycosides
|
WO2010018438A2
(en)
|
2008-08-11 |
2010-02-18 |
Hetero Research Foundation |
Tetrazole glycosides
|
WO2010019828A1
(en)
|
2008-08-13 |
2010-02-18 |
Metabasis Therapeutics, Inc. |
Glucagon receptor antagonists
|
JP2012500181A
(ja)
|
2008-08-15 |
2012-01-05 |
Msd株式会社 |
アセチルピロリジニルインドール誘導体
|
TW201215388A
(en)
*
|
2010-07-05 |
2012-04-16 |
Sanofi Sa |
(2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
|
TW201221505A
(en)
*
|
2010-07-05 |
2012-06-01 |
Sanofi Sa |
Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
|