WO2008099448A1 - 糖尿病性疾患の予防・治療剤 - Google Patents

糖尿病性疾患の予防・治療剤 Download PDF

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Publication number
WO2008099448A1
WO2008099448A1 PCT/JP2007/052328 JP2007052328W WO2008099448A1 WO 2008099448 A1 WO2008099448 A1 WO 2008099448A1 JP 2007052328 W JP2007052328 W JP 2007052328W WO 2008099448 A1 WO2008099448 A1 WO 2008099448A1
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WIPO (PCT)
Prior art keywords
diabetic
diabetic diseases
diseases
preventive
therapeutic agent
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PCT/JP2007/052328
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English (en)
French (fr)
Inventor
Masayoshi Yamaguchi
Original Assignee
Masayoshi Yamaguchi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Masayoshi Yamaguchi filed Critical Masayoshi Yamaguchi
Priority to PCT/JP2007/052328 priority Critical patent/WO2008099448A1/ja
Publication of WO2008099448A1 publication Critical patent/WO2008099448A1/ja

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Organic Chemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Mycology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

糖尿病性高血糖症、糖尿病性高脂血症、糖尿病性骨粗鬆症等の糖尿病性疾患を改善することができる、副作用の少ない糖尿病性疾患の予防・治療剤や、糖尿病性疾患の予防・改善用機能性食品又は食品素材を提供する。本発明は、ｐ－ヒドロキシケイ皮酸類を有効成分とし、糖尿病性疾患の予防・治療剤や、糖尿病性疾患の予防・改善用機能性食品又は食品素材とする。ｐ－ヒドロキシケイ皮酸類の糖尿病性疾患においては、血糖濃度の降下作用、血液中の脂肪酸エステル濃度の降下作用、血液中のカルシウム濃度の降下作用、血液中の無機リン濃度の上昇作用、骨幹部組織及び骨幹端部組織中のカルシウム濃度やＤＮＡ濃度やアルカリ性ホスファターゼ活性の上昇作用を有する。
PCT/JP2007/052328 2007-02-09 2007-02-09 糖尿病性疾患の予防・治療剤 WO2008099448A1 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/JP2007/052328 WO2008099448A1 (ja) 2007-02-09 2007-02-09 糖尿病性疾患の予防・治療剤

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP2007/052328 WO2008099448A1 (ja) 2007-02-09 2007-02-09 糖尿病性疾患の予防・治療剤

Publications (1)

Publication Number Publication Date
WO2008099448A1 true WO2008099448A1 (ja) 2008-08-21

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2007/052328 WO2008099448A1 (ja) 2007-02-09 2007-02-09 糖尿病性疾患の予防・治療剤

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WO (1) WO2008099448A1 (ja)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011107494A1 (de) 2010-03-03 2011-09-09 Sanofi Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
WO2011157827A1 (de) 2010-06-18 2011-12-22 Sanofi Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
WO2011161030A1 (de) 2010-06-21 2011-12-29 Sanofi Heterocyclisch substituierte methoxyphenylderivate mit oxogruppe, verfahren zu ihrer herstellung und ihre verwendung als gpr40 rezeptor modulatoren
WO2012004270A1 (de) 2010-07-05 2012-01-12 Sanofi Spirocyclisch substituierte 1,3-propandioxidderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
WO2012004269A1 (de) 2010-07-05 2012-01-12 Sanofi ( 2 -aryloxy -acetylamino) - phenyl - propionsäurederivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
WO2012010413A1 (de) 2010-07-05 2012-01-26 Sanofi Aryloxy-alkylen-substituierte hydroxy-phenyl-hexinsäuren, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
WO2013037390A1 (en) 2011-09-12 2013-03-21 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
WO2013045413A1 (en) 2011-09-27 2013-04-04 Sanofi 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002524505A (ja) * 1998-09-15 2002-08-06 コリア リサーチ インスティチュート オブ バイオサイエンス アンド バイオテクノロジー 高血中脂質濃度に因る疾患の予防または治療のための、ケイ皮酸誘導体を含む組成物
JP2003212774A (ja) * 2002-01-22 2003-07-30 Ichimaru Pharcos Co Ltd メイラード反応阻害剤
WO2006013750A1 (ja) * 2004-08-04 2006-02-09 Tokyo University Of Marine Science And Technology 脂質代謝調節作用を有する食品素材、健康食品、動物用飼料及び動物の飼育方法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002524505A (ja) * 1998-09-15 2002-08-06 コリア リサーチ インスティチュート オブ バイオサイエンス アンド バイオテクノロジー 高血中脂質濃度に因る疾患の予防または治療のための、ケイ皮酸誘導体を含む組成物
JP2003212774A (ja) * 2002-01-22 2003-07-30 Ichimaru Pharcos Co Ltd メイラード反応阻害剤
WO2006013750A1 (ja) * 2004-08-04 2006-02-09 Tokyo University Of Marine Science And Technology 脂質代謝調節作用を有する食品素材、健康食品、動物用飼料及び動物の飼育方法

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
KUMEDA Y. ET AL.: "Mansei Gappeisho Tonyobyo to Kotsusoshosho", JAPANESE JOURNAL OF CLINICAL MEDICINE, vol. 60, 28 October 2002 (2002-10-28), pages 393 - 403, XP003023227 *
OTA Y. ET AL.: "Gappeisho (Heizonsho) o Yusuru Tonyobyo no Byotai to Chiryo Koshi Kessho o Gappei suru Tonyobyo", JAPANESE JOURNAL OF CLINICAL MEDICINE, vol. 60, 28 October 2002 (2002-10-28), pages 424 - 429, XP003023226 *
YAMAGUCHI M.: "Regulatory Mechanism of Food Factors in Bone Metabolism and Prevention of Osteoporosis", YAKUGAKU ZASSHI, vol. 126, no. 11, 2006, pages 1117 - 1137, XP003018231 *

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011107494A1 (de) 2010-03-03 2011-09-09 Sanofi Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
WO2011157827A1 (de) 2010-06-18 2011-12-22 Sanofi Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
WO2011161030A1 (de) 2010-06-21 2011-12-29 Sanofi Heterocyclisch substituierte methoxyphenylderivate mit oxogruppe, verfahren zu ihrer herstellung und ihre verwendung als gpr40 rezeptor modulatoren
WO2012004270A1 (de) 2010-07-05 2012-01-12 Sanofi Spirocyclisch substituierte 1,3-propandioxidderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
WO2012004269A1 (de) 2010-07-05 2012-01-12 Sanofi ( 2 -aryloxy -acetylamino) - phenyl - propionsäurederivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
WO2012010413A1 (de) 2010-07-05 2012-01-26 Sanofi Aryloxy-alkylen-substituierte hydroxy-phenyl-hexinsäuren, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
WO2013037390A1 (en) 2011-09-12 2013-03-21 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
WO2013045413A1 (en) 2011-09-27 2013-04-04 Sanofi 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors

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