TW200722432A - Thiazole compounds - Google Patents
Thiazole compoundsInfo
- Publication number
- TW200722432A TW200722432A TW095110187A TW95110187A TW200722432A TW 200722432 A TW200722432 A TW 200722432A TW 095110187 A TW095110187 A TW 095110187A TW 95110187 A TW95110187 A TW 95110187A TW 200722432 A TW200722432 A TW 200722432A
- Authority
- TW
- Taiwan
- Prior art keywords
- hydrogen atom
- optionally substituted
- group
- thiazole compounds
- cf2p
- Prior art date
Links
- 150000003557 thiazoles Chemical class 0.000 title 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000001476 phosphono group Chemical group [H]OP(*)(=O)O[H] 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6536—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and sulfur atoms with or without oxygen atoms, as the only ring hetero atoms
- C07F9/6539—Five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Animal Behavior & Ethology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The subject of the present invention is to find out a prophylactic and/or therapeutic medicine for the diabetes etc. having an excellent actively and security. A compound of the following fomula (I), [wherein, each of the R1X and R1Y differently represents a hydrogen atom, a halogen atom, a C1-C6 alkyl group, P(O)(OH)2, OP(O)(OH)2, CH2P(O)(OH)2, CF2P(O)(OH)2, OCH2P(O)(OH)2, each of the R2 and R3 independently represents a hydrogen atom, an optionally substituted C1-C6 aliphatic acyl group, etc., R4 represents a hydrogen atom, an amino group, etc., X represents an optionally substituted C1-C3 alkylene group], or the pharmaceutically acceptable salt thereof is provided.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2005089010 | 2005-03-25 |
Publications (1)
Publication Number | Publication Date |
---|---|
TW200722432A true TW200722432A (en) | 2007-06-16 |
Family
ID=37053287
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW095110187A TW200722432A (en) | 2005-03-25 | 2006-03-24 | Thiazole compounds |
Country Status (2)
Country | Link |
---|---|
TW (1) | TW200722432A (en) |
WO (1) | WO2006104030A1 (en) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20090047458A (en) | 2006-08-08 | 2009-05-12 | 사노피-아벤티스 | Arylaminoaryl-alkyl-substituted imidazolidine-2,4-diones, processes for preparing them, medicaments comprising these compounds, and their use |
EP2025674A1 (en) | 2007-08-15 | 2009-02-18 | sanofi-aventis | Substituted tetra hydro naphthalines, method for their manufacture and their use as drugs |
EP2058308A1 (en) | 2007-11-12 | 2009-05-13 | Merck Sante | Benzimidazoledihydrothiadiazinone derivatives used as fructose-1,6-biphosphatase inhibitors and pharmaceutical compositions containing same. |
US8470841B2 (en) | 2008-07-09 | 2013-06-25 | Sanofi | Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof |
WO2010068601A1 (en) | 2008-12-08 | 2010-06-17 | Sanofi-Aventis | A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof |
RU2012111354A (en) | 2009-08-26 | 2013-10-10 | Санофи | NEW CRYSTALLINE HYDRATES OF FLUORGYCLOSIDES CONTAINING THEIR PHARMACEUTICAL DRUGS AND THEIR USE |
WO2011107494A1 (en) | 2010-03-03 | 2011-09-09 | Sanofi | Novel aromatic glycoside derivatives, medicaments containing said compounds, and the use thereof |
EP2582709B1 (en) | 2010-06-18 | 2018-01-24 | Sanofi | Azolopyridin-3-one derivatives as inhibitors of lipases and phospholipases |
US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
TW201221505A (en) | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
TW201215387A (en) | 2010-07-05 | 2012-04-16 | Sanofi Aventis | Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament |
WO2012120054A1 (en) | 2011-03-08 | 2012-09-13 | Sanofi | Di- and tri-substituted oxathiazine derivates, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
EP2683699B1 (en) | 2011-03-08 | 2015-06-24 | Sanofi | Di- and tri-substituted oxathiazine derivates, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
WO2012120056A1 (en) | 2011-03-08 | 2012-09-13 | Sanofi | Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof |
US8901114B2 (en) | 2011-03-08 | 2014-12-02 | Sanofi | Oxathiazine derivatives substituted with carbocycles or heterocycles, method for producing same, drugs containing said compounds, and use thereof |
US8828995B2 (en) | 2011-03-08 | 2014-09-09 | Sanofi | Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
WO2013037390A1 (en) | 2011-09-12 | 2013-03-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
WO2013045413A1 (en) | 2011-09-27 | 2013-04-04 | Sanofi | 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW260664B (en) * | 1993-02-15 | 1995-10-21 | Otsuka Pharma Factory Inc | |
AU773892B2 (en) * | 1999-06-30 | 2004-06-10 | H. Lundbeck A/S | Selective NPY (Y5) antagonists |
JP2004018489A (en) * | 2002-06-19 | 2004-01-22 | Otsuka Pharmaceut Factory Inc | Acat-1 inhibitor |
-
2006
- 2006-03-24 WO PCT/JP2006/305940 patent/WO2006104030A1/en active Application Filing
- 2006-03-24 TW TW095110187A patent/TW200722432A/en unknown
Also Published As
Publication number | Publication date |
---|---|
WO2006104030A1 (en) | 2006-10-05 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
TW200722432A (en) | Thiazole compounds | |
TW200745034A (en) | New compounds | |
TW200637869A (en) | The spiroketal derivatives and the use as therapeutical agent for diabetes of the same | |
TW200642683A (en) | Heterocyclic compound | |
TW200726470A (en) | 6,7-unsaturated-7-carbamoylmorphinan derivatives | |
WO2008114819A1 (en) | Novel adenine compound | |
TN2011000422A1 (en) | Benzofuran derivatives | |
MX2009003927A (en) | Thioglucose spiroketal derivative and use thereof as therapeutic agent for diabetes. | |
MY144960A (en) | Morpholine type cinnamide compound | |
MX2009012283A (en) | Nitrogen-containing heterocyclic derivative having 11 î²-hydroxysteroid dehydrogenase type i inhibitory activity. | |
TW200420542A (en) | A compound having TGF β inhibition activity and a medicinal composition containing the same | |
NO20052074L (en) | Substituted benzoxazinones and uses thereof. | |
MX2009004764A (en) | 5-hydroxymethyl-oxazolidin-2-one derivatives. | |
WO2008108380A3 (en) | Pyrrole compounds | |
WO2005012269A8 (en) | Novel azole compound | |
IN2014CN00613A (en) | ||
MX2008013728A (en) | Neurogenesis inducer or neuropathy therapeutic agent comprising alkyl ether derivative or salt thereof. | |
WO2007122634A3 (en) | Pyrimidinediones as tyrosine kinase inhibitors | |
WO2006088720A3 (en) | 9-substituted tetracyclines | |
TW200716527A (en) | Substituted aminoalkyl-and amidoalkyl-benzopyran derivatives | |
TW200612931A (en) | Substituted biphenyl derivatives | |
RS97004A (en) | Benzoxazine derivatives as 5-ht6 modulators and uses thereof | |
MX2010010471A (en) | Novel tetrahydroisoquinoline derivative. | |
MY138466A (en) | Aminoalkoxyndoles as 5-ht6-receptor ligands for the treatment of cns-disorders | |
TW200720265A (en) | Agent for treatment of hematopoietic tumor |