US7030219B2
(en)
|
2000-04-28 |
2006-04-18 |
Johns Hopkins University |
B7-DC, Dendritic cell co-stimulatory molecules
|
US7595048B2
(en)
|
2002-07-03 |
2009-09-29 |
Ono Pharmaceutical Co., Ltd. |
Method for treatment of cancer by inhibiting the immunosuppressive signal induced by PD-1
|
BR0316880A
(pt)
*
|
2002-12-23 |
2005-10-25 |
Wyeth Corp |
Anticorpos contra pd-1 e usos dos mesmos
|
WO2005091716A2
(en)
*
|
2004-03-26 |
2005-10-06 |
Quark Biotech, Inc. |
Annexin ii and uses thereof
|
MX2007004176A
(es)
*
|
2004-10-06 |
2007-06-15 |
Mayo Foundation |
B7-h1 y metodos de diagnosis, prognosis, y tratamiento de cancer.
|
EP1896582A4
(en)
*
|
2005-05-09 |
2009-04-08 |
Ono Pharmaceutical Co |
HUMAN MONOCLONAL ANTIBODIES FOR PROGRAMMED DEATH 1 (MP-1) AND METHODS FOR TREATING CANCER USING ANTI-MP-1 ANTIBODIES ALONE OR ASSOCIATED WITH OTHER IMMUNOTHERAPIES
|
AU2012204032B2
(en)
*
|
2005-06-08 |
2014-01-16 |
Dana-Farber Cancer Institute, Inc. |
Methods and compositions for the treatment of persistent infections and cancer by inhibiting the programmed cell death 1 (PD-1) pathway
|
LT2397156T
(lt)
|
2005-06-08 |
2017-02-27 |
Dana-Farber Cancer Institute, Inc. |
Būdai ir kompozicijos, skirti nuolatinių infekcijų ir vėžio gydymui inhibuojant užprogramuotos ląstelės mirties-1 (pd-1) kelią
|
CN101248089A
(zh)
|
2005-07-01 |
2008-08-20 |
米德列斯公司 |
抗程序性死亡配体1(pd-l1)的人单克隆抗体
|
EP1960009B1
(en)
|
2005-12-13 |
2011-11-23 |
The President and Fellows of Harvard College |
Scaffolds for cell transplantation
|
JP5093097B2
(ja)
|
2006-03-03 |
2012-12-05 |
小野薬品工業株式会社 |
細胞表面機能分子の細胞外領域多量体
|
DK2035549T3
(da)
|
2006-05-31 |
2014-10-13 |
Childrens Medical Center |
Abcb5-positive mesenkymale stamceller som immunmodulatorer
|
NZ619576A
(en)
*
|
2006-12-27 |
2014-07-25 |
Harvard College |
Compositions and methods for the treatment of infections and tumors
|
SI2644205T1
(sl)
|
2007-04-12 |
2018-11-30 |
The Brigham And Women's Hospital, Inc. |
Ciljanje ABCB5 za zdravljenje raka
|
PE20090321A1
(es)
*
|
2007-06-04 |
2009-04-20 |
Genentech Inc |
Anticuerpos anti-notch1 nrr, metodo de preparacion y composicion farmaceutica
|
KR20100054780A
(ko)
|
2007-06-18 |
2010-05-25 |
엔.브이.오가논 |
사람 프로그램된 사멸 수용체 pd-1에 대한 항체
|
AU2014201367B2
(en)
*
|
2007-06-18 |
2016-01-28 |
Merck Sharp & Dohme B.V. |
Antibodies to human programmed death receptor pd-1
|
EP2185689A2
(en)
|
2007-08-09 |
2010-05-19 |
Genzyme Corporation |
Method of treating autoimmune disease with mesenchymal stem cells
|
WO2009033009A2
(en)
*
|
2007-09-05 |
2009-03-12 |
Inotek Pharmaceuticals Corporation |
Antibodies against flagellin and uses thereof
|
US10328133B2
(en)
|
2008-02-13 |
2019-06-25 |
President And Fellows Of Harvard College |
Continuous cell programming devices
|
US8168757B2
(en)
*
|
2008-03-12 |
2012-05-01 |
Merck Sharp & Dohme Corp. |
PD-1 binding proteins
|
EP2853269B1
(en)
|
2008-05-19 |
2019-05-01 |
Advaxis, Inc. |
Dual delivery system for heterologous antigens comprising a recombinant Listeria strain attenuated by mutation of dal/dat and deletion of ActA comprising a nucleic acid molecule encoding an listeriolysin O - prostate specific anigen fusion protein
|
US9650639B2
(en)
|
2008-05-19 |
2017-05-16 |
Advaxis, Inc. |
Dual delivery system for heterologous antigens
|
US9017660B2
(en)
|
2009-11-11 |
2015-04-28 |
Advaxis, Inc. |
Compositions and methods for prevention of escape mutation in the treatment of Her2/neu over-expressing tumors
|
AU2009288730B2
(en)
|
2008-08-25 |
2013-06-20 |
Amplimmune, Inc. |
Compositions of PD-1 antagonists and methods of use
|
US20110159023A1
(en)
*
|
2008-08-25 |
2011-06-30 |
Solomon Langermann |
Pd-1 antagonists and methods for treating infectious disease
|
CA2736829C
(en)
*
|
2008-09-12 |
2018-02-27 |
Isis Innovation Limited |
Pd-1 specific antibodies and uses thereof
|
JP5794917B2
(ja)
*
|
2008-09-12 |
2015-10-14 |
アイシス・イノベーション・リミテッドIsis Innovationlimited |
Pd−1特異抗体およびその使用
|
EP3530672A1
(en)
*
|
2008-09-26 |
2019-08-28 |
Dana Farber Cancer Institute, Inc. |
Human anti-pd-1, pd-l1, and pd-l2 antibodies and uses thereof
|
PT2344540T
(pt)
|
2008-10-02 |
2018-02-02 |
Aptevo Res & Development Llc |
Proteínas de ligação multi-alvo antagonistas de cd86
|
EP3734281A3
(en)
|
2008-11-14 |
2021-01-27 |
The Brigham and Women's Hospital, Inc. |
Therapeutic and diagnostic methods relating to cancer stem cells
|
US11542328B2
(en)
|
2008-11-14 |
2023-01-03 |
The Brigham And Women's Hospital, Inc. |
Therapeutic and diagnostic methods relating to cancer stem cells
|
CN102282265B
(zh)
|
2008-11-28 |
2020-07-24 |
埃默里大学 |
用于治疗传染病和肿瘤的方法
|
CN102245640B
(zh)
|
2008-12-09 |
2014-12-31 |
霍夫曼-拉罗奇有限公司 |
抗-pd-l1抗体及它们用于增强t细胞功能的用途
|
JP5844159B2
(ja)
*
|
2009-02-09 |
2016-01-13 |
ユニヴェルシテ デクス−マルセイユUniversite D’Aix−Marseille |
Pd−1抗体およびpd−l1抗体ならびにその使用
|
US20100239583A1
(en)
*
|
2009-03-04 |
2010-09-23 |
Inotek Pharmaceuticals Corporation |
Antibodies against flagellin and uses thereof
|
EP2482849B1
(en)
*
|
2009-09-30 |
2018-06-06 |
Memorial Sloan-Kettering Cancer Center |
Combination immunotherapy for the treatment of cancer
|
US10016617B2
(en)
|
2009-11-11 |
2018-07-10 |
The Trustees Of The University Of Pennsylvania |
Combination immuno therapy and radiotherapy for the treatment of Her-2-positive cancers
|
WO2011100841A1
(en)
*
|
2010-02-16 |
2011-08-25 |
Valorisation-Recherche, Limited Partnership |
Pd-1 modulation and uses thereof for modulating hiv replication
|
US8993731B2
(en)
|
2010-03-11 |
2015-03-31 |
Ucb Biopharma Sprl |
PD-1 antibody
|
TW201134488A
(en)
|
2010-03-11 |
2011-10-16 |
Ucb Pharma Sa |
PD-1 antibodies
|
US20150231215A1
(en)
|
2012-06-22 |
2015-08-20 |
Randolph J. Noelle |
VISTA Antagonist and Methods of Use
|
US10745467B2
(en)
|
2010-03-26 |
2020-08-18 |
The Trustees Of Dartmouth College |
VISTA-Ig for treatment of autoimmune, allergic and inflammatory disorders
|
WO2011120013A2
(en)
|
2010-03-26 |
2011-09-29 |
Trustees Of Dartmouth College |
Vista regulatory t cell mediator protein, vista binding agents and use thereof
|
US9163087B2
(en)
*
|
2010-06-18 |
2015-10-20 |
The Brigham And Women's Hospital, Inc. |
Bi-specific antibodies against TIM-3 and PD-1 for immunotherapy in chronic immune conditions
|
US9783578B2
(en)
|
2010-06-25 |
2017-10-10 |
Aurigene Discovery Technologies Limited |
Immunosuppression modulating compounds
|
US8907053B2
(en)
|
2010-06-25 |
2014-12-09 |
Aurigene Discovery Technologies Limited |
Immunosuppression modulating compounds
|
JP6126991B2
(ja)
*
|
2010-09-27 |
2017-05-10 |
ヤンセン バイオテツク,インコーポレーテツド |
ヒトii型コラーゲンに結合する抗体
|
US8906649B2
(en)
|
2010-09-27 |
2014-12-09 |
Janssen Biotech, Inc. |
Antibodies binding human collagen II
|
WO2012138377A2
(en)
|
2010-10-01 |
2012-10-11 |
Trustees Of The University Of Pennsylvania |
The use of listeria vaccine vectors to reverse vaccine unresponsiveness in parasitically infected individuals
|
KR102155383B1
(ko)
|
2010-10-06 |
2020-09-11 |
프레지던트 앤드 펠로우즈 오브 하바드 칼리지 |
재료에 기초한 세포 치료를 위한 주사 가능한 기공 형성 하이드로겔
|
AU2012229218B2
(en)
|
2011-03-11 |
2017-03-02 |
Advaxis, Inc. |
Listeria-based adjuvants
|
RU2633509C2
(ru)
*
|
2011-03-31 |
2017-10-12 |
Мерк Шарп И Доум Корп. |
Стабильные составы антител против рецептора программируемой смерти pd-1 человека и относящиеся к ним способы лечения
|
CN105968209B
(zh)
|
2011-04-19 |
2021-08-03 |
美国政府(由卫生和人类服务部的部长所代表) |
对磷脂酰肌醇蛋白聚糖3特异的人单克隆抗体及其用途
|
EP2699264B1
(en)
|
2011-04-20 |
2018-03-14 |
Medlmmune, LLC |
Antibodies and other molecules that bind b7-h1 and pd-1
|
US9096642B2
(en)
|
2011-06-08 |
2015-08-04 |
Aurigene Discovery Technologies Limited |
Therapeutic compounds for immunomodulation
|
US10081684B2
(en)
|
2011-06-28 |
2018-09-25 |
Whitehead Institute For Biomedical Research |
Using sortases to install click chemistry handles for protein ligation
|
US9416132B2
(en)
|
2011-07-21 |
2016-08-16 |
Tolero Pharmaceuticals, Inc. |
Substituted imidazo[1,2-b]pyridazines as protein kinase inhibitors
|
EP2742953B1
(en)
*
|
2011-08-11 |
2021-09-22 |
ONO Pharmaceutical Co., Ltd. |
Therapeutic agent for autoimmune diseases comprising pd-1 agonist
|
SI2768524T1
(sl)
*
|
2011-10-17 |
2022-09-30 |
Io Biotech Aps |
Imunoterapija na osnovi PD-L1
|
CN104159911A
(zh)
|
2012-03-07 |
2014-11-19 |
奥瑞基尼探索技术有限公司 |
作为免疫调节剂的模拟肽化合物
|
SG10201700392UA
(en)
|
2012-03-12 |
2017-03-30 |
Advaxis Inc |
Suppressor cell function inhibition following listeria vaccine treatment
|
US9422339B2
(en)
|
2012-03-29 |
2016-08-23 |
Aurigene Discovery Technologies Limited |
Immunomodulating cyclic compounds
|
EP2836234B1
(en)
|
2012-04-12 |
2019-06-12 |
Yale University |
Vehicles for controlled delivery of different pharmaceutical agents
|
PT2838515T
(pt)
|
2012-04-16 |
2020-02-25 |
Harvard College |
Composições de sílica mesoporosa para modular respostas imunológicas
|
AU2013263076B2
(en)
|
2012-05-15 |
2017-08-31 |
Bristol-Myers Squibb Company |
Cancer immunotherapy by disrupting PD-1/PD-L1 signaling
|
KR102163408B1
(ko)
*
|
2012-05-31 |
2020-10-08 |
소렌토 쎄라퓨틱스, 인코포레이티드 |
Pd-l1에 결합하는 항원 결합 단백질
|
HUE042374T2
(hu)
|
2012-06-13 |
2019-06-28 |
Incyte Holdings Corp |
Szubsztituált triciklusos vegyületek mint FGFR inhibitorok
|
US9890215B2
(en)
|
2012-06-22 |
2018-02-13 |
King's College London |
Vista modulators for diagnosis and treatment of cancer
|
CN112587671A
(zh)
|
2012-07-18 |
2021-04-02 |
博笛生物科技有限公司 |
癌症的靶向免疫治疗
|
AU2013308595C1
(en)
|
2012-08-30 |
2019-01-17 |
Amgen Inc. |
A method for treating melanoma using a herpes simplex virus and an immune checkpoint inhibitor
|
CN109793893B
(zh)
|
2012-09-07 |
2023-05-26 |
达特茅斯大学理事会 |
用于诊断和治疗癌症的vista调节剂
|
US20150377891A1
(en)
|
2013-02-07 |
2015-12-31 |
(Institute National De La Santé Et De La Rechere Médicale) |
Methods for Predicting the Survival Time of Patients Suffering from Diffuse Large B-Cell Lymphomas
|
SG11201505896YA
(en)
|
2013-02-20 |
2015-09-29 |
Novartis Ag |
Treatment of cancer using humanized anti-egfrviii chimeric antigen receptor
|
UY35340A
(es)
|
2013-02-20 |
2014-09-30 |
Novartis Ag |
Marcaje efectivo de leucemia humana usando células diseñadas con un receptor quimérico de antígeno anti-cd123
|
PT2964638T
(pt)
|
2013-03-06 |
2017-11-14 |
Astrazeneca Ab |
Inibidores quinazolina de formas mutantes de ativação do recetor do fator de crescimento epidérmico
|
WO2014165082A2
(en)
*
|
2013-03-13 |
2014-10-09 |
Medimmune, Llc |
Antibodies and methods of detection
|
US9308236B2
(en)
|
2013-03-15 |
2016-04-12 |
Bristol-Myers Squibb Company |
Macrocyclic inhibitors of the PD-1/PD-L1 and CD80(B7-1)/PD-L1 protein/protein interactions
|
TWI654206B
(zh)
|
2013-03-16 |
2019-03-21 |
諾華公司 |
使用人類化抗-cd19嵌合抗原受體治療癌症
|
WO2014165422A1
(en)
|
2013-04-02 |
2014-10-09 |
Merck Sharp & Dohme Corp. |
Immunohistochemical assay for detecting expression of programmed death ligand 1 (pd-l1) in tumor tissue
|
EA201591931A1
(ru)
|
2013-04-09 |
2016-05-31 |
Ликсте Байотекнолоджи, Инк. |
Композиции оксабициклогептанов и оксабициклогептенов
|
CN106913865A
(zh)
|
2013-04-18 |
2017-07-04 |
阿尔莫生物科技股份有限公司 |
使用白细胞介素‑10治疗疾病和病症的方法
|
EA035095B1
(ru)
|
2013-04-19 |
2020-04-27 |
Инсайт Холдингс Корпорейшн |
Бициклические гетероциклы в качестве ингибиторов fgfr
|
HUE053069T2
(hu)
*
|
2013-05-02 |
2021-06-28 |
Anaptysbio Inc |
Programozott halál-1 (PD-1) ellen irányuló ellenanyagok
|
EP4119662A1
(en)
|
2013-05-10 |
2023-01-18 |
Whitehead Institute For Biomedical Research |
Protein modification of living cells using sortase
|
EP3546485A1
(en)
|
2013-05-10 |
2019-10-02 |
Whitehead Institute for Biomedical Research |
In vitro production of red blood cells with sortaggable proteins
|
WO2014194293A1
(en)
|
2013-05-30 |
2014-12-04 |
Amplimmune, Inc. |
Improved methods for the selection of patients for pd-1 or b7-h4 targeted therapies, and combination therapies thereof
|
WO2014194302A2
(en)
|
2013-05-31 |
2014-12-04 |
Sorrento Therapeutics, Inc. |
Antigen binding proteins that bind pd-1
|
ES2688206T3
(es)
|
2013-06-17 |
2018-10-31 |
Armo Biosciences, Inc. |
Procedimiento de evaluación de la identidad y la estabilidad de proteínas
|
DK3030682T3
(da)
|
2013-08-05 |
2020-09-14 |
Twist Bioscience Corp |
De novo synthesized gene libraries
|
JP6794255B2
(ja)
|
2013-08-08 |
2020-12-02 |
サイチューン ファーマ |
組合せ医薬組成物
|
SI3444271T1
(sl)
|
2013-08-08 |
2022-03-31 |
Cytune Pharma |
Modulokini na osnovi IL-15 in IL-15Ralfa sushi domene
|
CA2920113A1
(en)
|
2013-08-20 |
2015-02-26 |
Merck Sharp & Dohme Corp. |
Treating cancer with a combination of a pd-1 antagonist and dinaciclib
|
AR097306A1
(es)
|
2013-08-20 |
2016-03-02 |
Merck Sharp & Dohme |
Modulación de la inmunidad tumoral
|
EP3038642A4
(en)
|
2013-08-30 |
2017-01-18 |
Armo Biosciences, Inc. |
Methods of using interleukin-10 for treating diseases and disorders
|
CU24363B1
(es)
|
2013-09-06 |
2018-10-04 |
Aurigene Discovery Tech Ltd |
Compuestos peptidomiméticos cíclicos
|
EP3041828B1
(en)
|
2013-09-06 |
2018-05-23 |
Aurigene Discovery Technologies Limited |
1,3,4-oxadiazole and 1,3,4-thiadiazole derivatives as immunomodulators
|
TR201809838T4
(tr)
|
2013-09-06 |
2018-07-23 |
Aurigene Discovery Tech Ltd |
İmmünomodülatörler olarak 1,2,4-oksadiazol türevleri.
|
WO2015036394A1
(en)
*
|
2013-09-10 |
2015-03-19 |
Medimmune Limited |
Antibodies against pd-1 and uses thereof
|
EP4130044A1
(en)
|
2013-09-13 |
2023-02-08 |
BeiGene Switzerland GmbH |
Anti-pd1 antibodies and their use as therapeutics and diagnostics
|
WO2015048312A1
(en)
|
2013-09-26 |
2015-04-02 |
Costim Pharmaceuticals Inc. |
Methods for treating hematologic cancers
|
CN104558177B
(zh)
*
|
2013-10-25 |
2020-02-18 |
苏州思坦维生物技术股份有限公司 |
拮抗抑制程序性死亡受体pd-1与其配体结合的单克隆抗体及其编码序列与用途
|
WO2015066413A1
(en)
|
2013-11-01 |
2015-05-07 |
Novartis Ag |
Oxazolidinone hydroxamic acid compounds for the treatment of bacterial infections
|
CA2929277C
(en)
|
2013-11-01 |
2018-01-16 |
Yale University |
Delivery vehicles comprising il-2 and losartan
|
AU2014346537A1
(en)
|
2013-11-11 |
2016-05-19 |
Armo Biosciences, Inc. |
Methods of using interleukin-10 for treating diseases and disorders
|
US20150140036A1
(en)
|
2013-11-13 |
2015-05-21 |
Novartis Institutes For Biomedical Research, Inc. |
Low, immune enhancing, dose mtor inhibitors and uses thereof
|
US10556024B2
(en)
|
2013-11-13 |
2020-02-11 |
Whitehead Institute For Biomedical Research |
18F labeling of proteins using sortases
|
EP3079772B1
(en)
|
2013-12-10 |
2020-02-05 |
Merck Sharp & Dohme Corp. |
Immunohistochemical proximity assay for pd-1 positive cells and pd-ligand positive cells in tumor tissue
|
SG11201604738TA
(en)
|
2013-12-12 |
2016-07-28 |
Shanghai Hengrui Pharm Co Ltd |
Pd-1 antibody, antigen-binding fragment thereof, and medical application thereof
|
EP3084003A4
(en)
|
2013-12-17 |
2017-07-19 |
Merck Sharp & Dohme Corp. |
Ifn-gamma gene signature biomarkers of tumor response to pd-1 antagonists
|
RU2714902C2
(ru)
|
2013-12-19 |
2020-02-20 |
Новартис Аг |
Химерные рецепторы антигена против мезотелина человека и их применение
|
US11014987B2
(en)
|
2013-12-24 |
2021-05-25 |
Janssen Pharmaceutics Nv |
Anti-vista antibodies and fragments, uses thereof, and methods of identifying same
|
CA2935378C
(en)
|
2013-12-24 |
2023-04-18 |
Janssen Pharmaceutica Nv |
Anti-vista antibodies and fragments
|
WO2015103989A1
(en)
|
2014-01-10 |
2015-07-16 |
Shanghai Birdie Biotech, Inc. |
Compounds and compositions for immunotherapy
|
JO3517B1
(ar)
|
2014-01-17 |
2020-07-05 |
Novartis Ag |
ان-ازاسبيرو الكان حلقي كبديل مركبات اريل-ان مغايرة وتركيبات لتثبيط نشاط shp2
|
TWI680138B
(zh)
|
2014-01-23 |
2019-12-21 |
美商再生元醫藥公司 |
抗pd-l1之人類抗體
|
TWI681969B
(zh)
*
|
2014-01-23 |
2020-01-11 |
美商再生元醫藥公司 |
針對pd-1的人類抗體
|
JOP20200094A1
(ar)
*
|
2014-01-24 |
2017-06-16 |
Dana Farber Cancer Inst Inc |
جزيئات جسم مضاد لـ pd-1 واستخداماتها
|
JOP20200096A1
(ar)
|
2014-01-31 |
2017-06-16 |
Children’S Medical Center Corp |
جزيئات جسم مضاد لـ tim-3 واستخداماتها
|
SG11201605824XA
(en)
|
2014-02-04 |
2016-08-30 |
Pfizer |
Combination of a pd-1 antagonist and a vegfr inhibitor for treating cancer
|
EP3686219A1
(en)
|
2014-02-04 |
2020-07-29 |
Pfizer Inc |
Combination of a pd-1 antagonist and a 4-1bb agonist for treating cancer
|
CA2938566A1
(en)
|
2014-02-04 |
2015-08-13 |
Incyte Corporation |
Combination of a pd-1 antagonist and an ido1 inhibitor for treating cancer
|
CN106255510A
(zh)
|
2014-03-05 |
2016-12-21 |
百时美施贵宝公司 |
使用抗pd‑1抗体与另一抗癌剂的组合治疗肾癌
|
TWI777174B
(zh)
|
2014-03-14 |
2022-09-11 |
瑞士商諾華公司 |
針對lag-3之抗體分子及其用途
|
WO2015142675A2
(en)
|
2014-03-15 |
2015-09-24 |
Novartis Ag |
Treatment of cancer using chimeric antigen receptor
|
UA121383C2
(uk)
|
2014-03-24 |
2020-05-25 |
Новартіс Аг |
Органічні сполуки, що є монобактамами, для лікування бактеріальних інфекцій
|
KR102651707B1
(ko)
|
2014-04-07 |
2024-03-29 |
노파르티스 아게 |
항-cd19 키메라 항원 수용체를 사용한 암의 치료
|
JP7348708B2
(ja)
*
|
2014-04-30 |
2023-09-21 |
プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ |
組み合わせワクチン装置および癌細胞を殺滅する方法
|
RU2695332C2
(ru)
|
2014-05-15 |
2019-07-23 |
Бристол-Маерс Сквибб Компани |
Лечение рака легкого с помощью комбинации антитела против pd-1 и другого противоракового средства
|
EP3134085A1
(en)
|
2014-05-23 |
2017-03-01 |
Eisai R&D Management Co., Ltd. |
Combination therapies for the treatment of cancer
|
NZ726513A
(en)
|
2014-05-28 |
2023-07-28 |
Memorial Sloan Kettering Cancer Center |
Anti-gitr antibodies and methods of use thereof
|
AU2015265607A1
(en)
|
2014-05-28 |
2016-11-17 |
Idenix Pharmaceuticals Llc |
Nucleoside derivatives for the treatment of cancer
|
US10293043B2
(en)
|
2014-06-02 |
2019-05-21 |
Armo Biosciences, Inc. |
Methods of lowering serum cholesterol
|
RS59643B1
(sr)
|
2014-06-06 |
2020-01-31 |
Bristol Myers Squibb Co |
Antitela na glukokortikoidom indukovani receptor faktora nekroze tumora (gitr) i njihova primena
|
MX2016016310A
(es)
|
2014-06-11 |
2017-10-20 |
A Green Kathy |
Uso de agonistas y antagonistas vista para suprimir o aumentar la inmunidad humoral.
|
US10092645B2
(en)
|
2014-06-17 |
2018-10-09 |
Medimmune Limited |
Methods of treatment with antagonists against PD-1 and PD-L1 in combination with radiation therapy
|
KR102482295B1
(ko)
|
2014-06-19 |
2022-12-30 |
리제너론 파마슈티칼스 인코포레이티드 |
인간화 프로그램화 세포 사멸 1 유전자를 가지는 비인간 동물
|
TWI693232B
(zh)
|
2014-06-26 |
2020-05-11 |
美商宏觀基因股份有限公司 |
與pd-1和lag-3具有免疫反應性的共價結合的雙抗體和其使用方法
|
TWI726608B
(zh)
|
2014-07-03 |
2021-05-01 |
英屬開曼群島商百濟神州有限公司 |
抗pd-l1抗體及其作為治療及診斷之用途
|
DK3166976T3
(da)
|
2014-07-09 |
2022-04-11 |
Birdie Biopharmaceuticals Inc |
Anti-pd-l1-kombinationer til behandling af tumorer
|
US10555981B2
(en)
|
2014-07-16 |
2020-02-11 |
Transgene S.A. |
Oncolytic virus for expression of immune checkpoint modulators
|
DK3169340T3
(da)
|
2014-07-16 |
2020-11-09 |
Roussy Inst Gustave |
Kombination af onkolytisk virus med immun-checkpoint-modulatorer
|
MX2017000857A
(es)
|
2014-07-18 |
2017-10-11 |
Advaxis Inc |
Combinación de un antagonista de la proteina de muerte programada (pd-1) y una vacuna basada en listeria para tratar el cáncer de próstata.
|
WO2016014553A1
(en)
|
2014-07-21 |
2016-01-28 |
Novartis Ag |
Sortase synthesized chimeric antigen receptors
|
US9777061B2
(en)
|
2014-07-21 |
2017-10-03 |
Novartis Ag |
Treatment of cancer using a CD33 chimeric antigen receptor
|
WO2016014530A1
(en)
|
2014-07-21 |
2016-01-28 |
Novartis Ag |
Combinations of low, immune enhancing. doses of mtor inhibitors and cars
|
KR102524920B1
(ko)
|
2014-07-22 |
2023-04-25 |
아폴로믹스 인코포레이티드 |
항-pd-1 항체
|
CN105330740B
(zh)
*
|
2014-07-30 |
2018-08-17 |
珠海市丽珠单抗生物技术有限公司 |
抗pd-1抗体及其应用
|
US20170209492A1
(en)
|
2014-07-31 |
2017-07-27 |
Novartis Ag |
Subset-optimized chimeric antigen receptor-containing t-cells
|
US9982052B2
(en)
|
2014-08-05 |
2018-05-29 |
MabQuest, SA |
Immunological reagents
|
CN110964108B
(zh)
|
2014-08-05 |
2023-07-07 |
中美冠科生物技术(太仓)有限公司 |
抗pd-l1抗体
|
US9982053B2
(en)
*
|
2014-08-05 |
2018-05-29 |
MabQuest, SA |
Immunological reagents
|
EP3177593A1
(en)
|
2014-08-06 |
2017-06-14 |
Novartis AG |
Quinolone derivatives as antibacterials
|
JP6919118B2
(ja)
|
2014-08-14 |
2021-08-18 |
ノバルティス アーゲー |
GFRα−4キメラ抗原受容体を用いる癌の治療
|
BR112017003104A2
(pt)
|
2014-08-19 |
2017-12-05 |
Novartis Ag |
tratamento de câncer usando um receptor antigênico quimérico anti-cd123
|
WO2016032927A1
(en)
|
2014-08-25 |
2016-03-03 |
Pfizer Inc. |
Combination of a pd-1 antagonist and an alk inhibitor for treating cancer
|
CN112587672A
(zh)
|
2014-09-01 |
2021-04-02 |
博笛生物科技有限公司 |
用于治疗肿瘤的抗-pd-l1结合物
|
US9535074B2
(en)
|
2014-09-08 |
2017-01-03 |
Merck Sharp & Dohme Corp. |
Immunoassay for soluble PD-L1
|
MX2017003227A
(es)
|
2014-09-13 |
2017-12-04 |
Novartis Ag |
Terapias de combinacion de inhibidores de alk.
|
ES2825576T3
(es)
*
|
2014-09-16 |
2021-05-17 |
Innate Pharma |
Neutralización de rutas inhibidoras en linfocitos
|
US10577417B2
(en)
|
2014-09-17 |
2020-03-03 |
Novartis Ag |
Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy
|
ES2774448T3
(es)
|
2014-10-03 |
2020-07-21 |
Novartis Ag |
Terapias de combinación
|
US10053683B2
(en)
|
2014-10-03 |
2018-08-21 |
Whitehead Institute For Biomedical Research |
Intercellular labeling of ligand-receptor interactions
|
MA41044A
(fr)
|
2014-10-08 |
2017-08-15 |
Novartis Ag |
Compositions et procédés d'utilisation pour une réponse immunitaire accrue et traitement contre le cancer
|
SG11201702895SA
(en)
|
2014-10-08 |
2017-05-30 |
Novartis Ag |
Biomarkers predictive of therapeutic responsiveness to chimeric antigen receptor therapy and uses thereof
|
US9732119B2
(en)
|
2014-10-10 |
2017-08-15 |
Bristol-Myers Squibb Company |
Immunomodulators
|
ES2908056T3
(es)
|
2014-10-10 |
2022-04-27 |
Idera Pharmaceuticals Inc |
Tratamiento del cáncer por agonistas del TLR9 con inhibidores del punto de control
|
KR20170068553A
(ko)
|
2014-10-14 |
2017-06-19 |
아르모 바이오사이언시스 인코포레이티드 |
인터류킨-15 조성물 및 이의 용도
|
TWI716362B
(zh)
|
2014-10-14 |
2021-01-21 |
瑞士商諾華公司 |
針對pd-l1之抗體分子及其用途
|
KR20170084033A
(ko)
|
2014-10-22 |
2017-07-19 |
아르모 바이오사이언시스 인코포레이티드 |
질환 및 장애를 치료하기 위해 인터루킨-10을 사용하는 방법
|
GB201419084D0
(en)
|
2014-10-27 |
2014-12-10 |
Agency Science Tech & Res |
Anti-PD-1 antibodies
|
AU2015339306B2
(en)
|
2014-10-29 |
2021-07-22 |
Bristol-Myers Squibb Company |
Combination therapy for cancer
|
WO2016073759A1
(en)
|
2014-11-05 |
2016-05-12 |
The Regents Of The University Of California |
Combination immunotherapy
|
US10822414B2
(en)
|
2014-11-11 |
2020-11-03 |
Sutro Biopharma, Inc. |
Anti-PD-1 antibodies, compositions comprising anti-PD-1 antibodies and methods of using anti-PD-1 antibodies
|
US20170313775A1
(en)
|
2014-11-13 |
2017-11-02 |
The Johns Hopkins University |
Checkpoint Blockade and Microsatellite Instability
|
CA2967188A1
(en)
|
2014-11-14 |
2016-05-19 |
Novartis Ag |
Antibody drug conjugates
|
US9856292B2
(en)
|
2014-11-14 |
2018-01-02 |
Bristol-Myers Squibb Company |
Immunomodulators
|
US20160169869A1
(en)
|
2014-11-20 |
2016-06-16 |
Promega Corporation |
Systems and methods for assessing modulators of immune checkpoints
|
US20180334490A1
(en)
|
2014-12-03 |
2018-11-22 |
Qilong H. Wu |
Methods for b cell preconditioning in car therapy
|
SG11201704343SA
(en)
|
2014-12-04 |
2017-06-29 |
Bristol Myers Squibb Co |
Combination of anti-cs1 and anti-pd1 antibodies to treat cancer (myeloma)
|
EP3226688B1
(en)
|
2014-12-05 |
2020-07-01 |
Merck Sharp & Dohme Corp. |
Tricyclic compounds as inhibitors of mutant idh enzymes
|
JP2018505911A
(ja)
|
2014-12-05 |
2018-03-01 |
イミュネクスト,インコーポレーテッド |
推定上のvista受容体としてのvsig8の同定と、vista/vsig8調節剤を産生するためのその使用
|
US10086000B2
(en)
|
2014-12-05 |
2018-10-02 |
Merck Sharp & Dohme Corp. |
Tricyclic compounds as inhibitors of mutant IDH enzymes
|
WO2016089830A1
(en)
|
2014-12-05 |
2016-06-09 |
Merck Sharp & Dohme Corp. |
Novel tricyclic compounds as inhibitors of mutant idh enzymes
|
TWI595006B
(zh)
|
2014-12-09 |
2017-08-11 |
禮納特神經系統科學公司 |
抗pd-1抗體類和使用彼等之方法
|
US11377693B2
(en)
|
2014-12-09 |
2022-07-05 |
Merck Sharp & Dohme Llc |
System and methods for deriving gene signature biomarkers of response to PD-1 antagonists
|
JP2018500896A
(ja)
|
2014-12-09 |
2018-01-18 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッドRegeneron Pharmaceuticals, Inc. |
ヒト化分化抗原群274遺伝子を有する非ヒト動物
|
ME03546B
(me)
|
2014-12-16 |
2020-07-20 |
Novartis Ag |
Jedinjenja izoksazol hidroksamske kiseline kао inhibiтori lpxc
|
US9861680B2
(en)
|
2014-12-18 |
2018-01-09 |
Bristol-Myers Squibb Company |
Immunomodulators
|
CA2971201A1
(en)
|
2014-12-18 |
2016-06-23 |
Amgen Inc. |
Stable frozen herpes simplex virus formulation
|
EP3234193B1
(en)
|
2014-12-19 |
2020-07-15 |
Massachusetts Institute of Technology |
Molecular biomarkers for cancer immunotherapy
|
EP3233918A1
(en)
|
2014-12-19 |
2017-10-25 |
Novartis AG |
Combination therapies
|
US9944678B2
(en)
|
2014-12-19 |
2018-04-17 |
Bristol-Myers Squibb Company |
Immunomodulators
|
WO2016109310A1
(en)
|
2014-12-31 |
2016-07-07 |
Checkmate Pharmaceuticals, Llc |
Combination tumor immunotherapy
|
CN107428818A
(zh)
|
2015-01-29 |
2017-12-01 |
密西根州立大学校董会 |
隐藏多肽及其用途
|
EP3250250A4
(en)
|
2015-01-30 |
2019-05-22 |
President and Fellows of Harvard College |
PERITUMORAL AND INTRATUMORAL MATERIALS FOR CANCER THERAPY
|
US11161907B2
(en)
|
2015-02-02 |
2021-11-02 |
Novartis Ag |
Car-expressing cells against multiple tumor antigens and uses thereof
|
WO2016126615A1
(en)
|
2015-02-03 |
2016-08-11 |
Armo Biosciences, Inc. |
Methods of using interleukin-10 for treating diseases and disorders
|
US20160222060A1
(en)
|
2015-02-04 |
2016-08-04 |
Bristol-Myers Squibb Company |
Immunomodulators
|
CN113004278B
(zh)
|
2015-02-20 |
2023-07-21 |
因赛特控股公司 |
作为fgfr抑制剂的双环杂环
|
MA41551A
(fr)
|
2015-02-20 |
2017-12-26 |
Incyte Corp |
Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4
|
SG10201810615VA
(en)
|
2015-02-26 |
2019-01-30 |
Merck Patent Gmbh |
Pd-1 / pd-l1 inhibitors for the treatment of cancer
|
AU2015384801B2
(en)
|
2015-03-04 |
2022-01-06 |
Eisai R&D Management Co., Ltd. |
Combination of a PD-1 antagonist and a VEGFR/FGFR/RET tyrosine kinase inhibitor for treating cancer
|
WO2016141209A1
(en)
|
2015-03-04 |
2016-09-09 |
Merck Sharp & Dohme Corp. |
Combination of a pd-1 antagonist and eribulin for treating cancer
|
KR102623404B1
(ko)
|
2015-03-06 |
2024-01-11 |
비욘드스프링 파마수티컬스, 인코포레이티드. |
뇌 종양 치료 방법
|
WO2016144635A1
(en)
|
2015-03-06 |
2016-09-15 |
Beyondspring Pharmaceuticals, Inc. |
Method of treating cancer associated with a ras mutation
|
CU24509B1
(es)
|
2015-03-10 |
2021-05-12 |
Aurigene Discovery Tech Ltd |
Compuestos de 1,2,4-oxadiazol y tiadiazol como inmunomoduladores
|
TN2017000375A1
(en)
|
2015-03-10 |
2019-01-16 |
Aduro Biotech Inc |
Compositions and methods for activating "stimulator of interferon gene" -dependent signalling
|
US9809625B2
(en)
|
2015-03-18 |
2017-11-07 |
Bristol-Myers Squibb Company |
Immunomodulators
|
WO2016154177A2
(en)
|
2015-03-23 |
2016-09-29 |
Jounce Therapeutics, Inc. |
Antibodies to icos
|
EP3277320A4
(en)
*
|
2015-03-30 |
2018-08-01 |
Stcube, Inc. |
Antibodies specific to glycosylated pd-l1 and methods of use thereof
|
ES2820768T3
(es)
|
2015-04-03 |
2021-04-22 |
Xoma Technology Ltd |
Tratamiento del cáncer usando inhibidores de TGF-beta y PD-1
|
WO2016164580A1
(en)
|
2015-04-07 |
2016-10-13 |
Novartis Ag |
Combination of chimeric antigen receptor therapy and amino pyrimidine derivatives
|
US11150242B2
(en)
|
2015-04-10 |
2021-10-19 |
President And Fellows Of Harvard College |
Immune cell trapping devices and methods for making and using the same
|
EP4234685A3
(en)
|
2015-04-17 |
2023-09-06 |
Novartis AG |
Methods for improving the efficacy and expansion of chimeric antigen receptor-expressing cells
|
US11326211B2
(en)
|
2015-04-17 |
2022-05-10 |
Merck Sharp & Dohme Corp. |
Blood-based biomarkers of tumor sensitivity to PD-1 antagonists
|
EP3283107B1
(en)
|
2015-04-17 |
2020-05-27 |
Bristol-Myers Squibb Company |
Compositions comprising a combination of ipilimumab and nivolumab
|
WO2016172377A1
(en)
|
2015-04-21 |
2016-10-27 |
Twist Bioscience Corporation |
Devices and methods for oligonucleic acid library synthesis
|
EP3286211A1
(en)
|
2015-04-23 |
2018-02-28 |
Novartis AG |
Treatment of cancer using chimeric antigen receptor and protein kinase a blocker
|
JP2018514550A
(ja)
|
2015-04-28 |
2018-06-07 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
抗pd−1抗体および抗ctla−4抗体を使用するpd−l1陰性黒色腫の処置
|
US20160362489A1
(en)
|
2015-04-28 |
2016-12-15 |
Bristol-Myers Squibb Company |
Treatment of PD-L1-Positive Melanoma Using an Anti-PD-1 Antibody
|
US20180104331A1
(en)
|
2015-05-11 |
2018-04-19 |
The Johns Hopkins University |
Autoimmune antibodies for use in inhibiting cancer cell growth
|
US10815264B2
(en)
|
2015-05-27 |
2020-10-27 |
Southern Research Institute |
Nucleotides for the treatment of cancer
|
US20180155429A1
(en)
*
|
2015-05-28 |
2018-06-07 |
Bristol-Myers Squibb Company |
Treatment of pd-l1 positive lung cancer using an anti-pd-1 antibody
|
CA2986755A1
(en)
|
2015-05-28 |
2016-12-01 |
Armo Biosciences, Inc. |
Pegylated interleukin-10 for use in treating cancer
|
WO2016196389A1
(en)
|
2015-05-29 |
2016-12-08 |
Bristol-Myers Squibb Company |
Treatment of renal cell carcinoma
|
HUE050750T2
(hu)
|
2015-05-29 |
2021-01-28 |
Agenus Inc |
CTLA-4 elleni antitestek és eljárások alkalmazásukra
|
KR20180014009A
(ko)
|
2015-05-29 |
2018-02-07 |
머크 샤프 앤드 돔 코포레이션 |
암을 치료하기 위한 pd-1 길항제 및 cpg-c 유형 올리고뉴클레오티드의 조합
|
WO2016196218A1
(en)
|
2015-05-31 |
2016-12-08 |
Curegenix Corporation |
Combination compositions for immunotherapy
|
TWI773646B
(zh)
|
2015-06-08 |
2022-08-11 |
美商宏觀基因股份有限公司 |
結合lag-3的分子和其使用方法
|
TW201709929A
(zh)
|
2015-06-12 |
2017-03-16 |
宏觀基因股份有限公司 |
治療癌症的聯合療法
|
US20180179282A1
(en)
|
2015-06-12 |
2018-06-28 |
Bristol-Myers Squibb Company |
Treatment of cancer by combined blockade of the pd-1 and cxcr4 signaling pathways
|
MX2017016324A
(es)
|
2015-06-16 |
2018-03-02 |
Merck Patent Gmbh |
Tratamientos de combinacion de antagonista de ligando 1 de muerte programada (pd-l1).
|
JP2018526972A
(ja)
*
|
2015-06-16 |
2018-09-20 |
ジェネンテック, インコーポレイテッド |
抗cd3抗体及び使用方法
|
EP3310813A1
(en)
|
2015-06-17 |
2018-04-25 |
Novartis AG |
Antibody drug conjugates
|
TWI773647B
(zh)
|
2015-06-23 |
2022-08-11 |
史隆凱特林紀念癌症中心 |
新穎pd-1免疫調控劑
|
CN107922497B
(zh)
|
2015-06-24 |
2022-04-12 |
詹森药业有限公司 |
抗vista抗体和片段
|
AU2016288246A1
(en)
|
2015-07-02 |
2018-02-01 |
Celgene Corporation |
Combination therapy for treatment of hematological cancers and solid tumors
|
GB201511790D0
(en)
|
2015-07-06 |
2015-08-19 |
Iomet Pharma Ltd |
Pharmaceutical compound
|
AU2016294440B2
(en)
|
2015-07-13 |
2022-10-13 |
Cytomx Therapeutics, Inc |
Anti-PD-1 antibodies, activatable anti-PD-1 antibodies, and methods of use thereof
|
AU2016291708B2
(en)
|
2015-07-13 |
2020-12-24 |
Beyondspring Pharmaceuticals, Inc |
Plinabulin compositions
|
EP3322731B1
(en)
|
2015-07-14 |
2021-01-13 |
Bristol-Myers Squibb Company |
Method of treating cancer using immune checkpoint inhibitor; antibody that binds to programmed death-1 receptor (pd-1) or programmed death ligand 1 (pd-l1)
|
CN111375066B
(zh)
|
2015-07-16 |
2023-04-25 |
百欧肯治疗有限公司 |
治疗癌症的组合物及方法
|
KR20180036974A
(ko)
|
2015-07-16 |
2018-04-10 |
바이오엑셀 테라퓨틱스 인코포레이티드 |
면역조절을 이용하는 암의 치료를 위한 신규한 접근법
|
EP3325504A1
(en)
|
2015-07-21 |
2018-05-30 |
Novartis AG |
Methods for improving the efficacy and expansion of immune cells
|
CN106699888B
(zh)
*
|
2015-07-28 |
2020-11-06 |
上海昀怡健康科技发展有限公司 |
一种pd-1抗体及其制备方法和应用
|
RU2018105846A
(ru)
|
2015-07-29 |
2019-08-28 |
Новартис Аг |
Комбинация антагониста pd-1 с ингибитором egfr
|
EP3328425B1
(en)
|
2015-07-29 |
2021-08-25 |
Novartis AG |
Combined use of anti pd-1 and anti m-csf antibodies in the treatment of cancer
|
SI3317301T1
(sl)
|
2015-07-29 |
2021-10-29 |
Novartis Ag |
Kombinirane terapije, ki obsegajo molekule protitelesa na LAG-3
|
WO2017019897A1
(en)
|
2015-07-29 |
2017-02-02 |
Novartis Ag |
Combination therapies comprising antibody molecules to tim-3
|
EP3328419B1
(en)
|
2015-07-30 |
2021-08-25 |
MacroGenics, Inc. |
Pd-1-binding molecules and methods of use thereof
|
US20190023791A1
(en)
|
2015-08-04 |
2019-01-24 |
Glaxosmithkline Intellectual Property Development Limited |
Combination Treatments and Uses and Methods Thereof
|
EP3331918A1
(en)
|
2015-08-04 |
2018-06-13 |
GlaxoSmithKline Intellectual Property Development Limited |
Combination treatments and uses and methods thereof
|
RU2018107991A
(ru)
|
2015-08-07 |
2019-09-09 |
ПИЕРИС ФАРМАСЬЮТИКАЛС ГмбХ |
Новый слитый полипептид, специфичный в отношении lag-3 и pd-1
|
US20180230431A1
(en)
|
2015-08-07 |
2018-08-16 |
Glaxosmithkline Intellectual Property Development Limited |
Combination Therapy
|
WO2017024465A1
(en)
*
|
2015-08-10 |
2017-02-16 |
Innovent Biologics (Suzhou) Co., Ltd. |
Pd-1 antibodies
|
KR102055396B1
(ko)
*
|
2015-08-11 |
2019-12-12 |
우시 바이올로직스 (케이만) 인코포레이티드 |
신규한 항-pd-1 항체
|
JP6596146B2
(ja)
|
2015-08-13 |
2019-10-23 |
メルク・シャープ・アンド・ドーム・コーポレーション |
Stingアゴニストとしての環状ジヌクレオチド化合物
|
US11453697B1
(en)
|
2015-08-13 |
2022-09-27 |
Merck Sharp & Dohme Llc |
Cyclic di-nucleotide compounds as sting agonists
|
US11014983B2
(en)
|
2015-08-20 |
2021-05-25 |
Sutro Biopharma, Inc. |
Anti-Tim-3 antibodies, compositions comprising anti-Tim-3 antibodies and methods of making and using anti-Tim-3 antibodies
|
MX2018002298A
(es)
|
2015-08-25 |
2018-07-06 |
Armo Biosciences Inc |
Metodos de uso de interleucina 10 para el tratamiento de enfermedades y trastornos.
|
WO2017032867A1
(en)
|
2015-08-27 |
2017-03-02 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting the survival time of patients suffering from a lung cancer
|
WO2017040790A1
(en)
|
2015-09-01 |
2017-03-09 |
Agenus Inc. |
Anti-pd-1 antibodies and methods of use thereof
|
RU2760582C2
(ru)
|
2015-09-02 |
2021-11-29 |
Иммутеп С.А.С. |
Анти-LAG-3 антитела
|
CN108348571B
(zh)
|
2015-09-03 |
2022-03-22 |
艾瑞朗医疗公司 |
拟肽大环化合物及其用途
|
US11747346B2
(en)
|
2015-09-03 |
2023-09-05 |
Novartis Ag |
Biomarkers predictive of cytokine release syndrome
|
WO2017049231A1
(en)
|
2015-09-18 |
2017-03-23 |
Twist Bioscience Corporation |
Oligonucleic acid variant libraries and synthesis thereof
|
US11512347B2
(en)
|
2015-09-22 |
2022-11-29 |
Twist Bioscience Corporation |
Flexible substrates for nucleic acid synthesis
|
WO2017055325A1
(en)
|
2015-09-29 |
2017-04-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for quantifying the population of nk cells in a tissue sample
|
WO2017055324A1
(en)
|
2015-09-29 |
2017-04-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for quantifying the population of cells of monocytic origin in a tissue sample
|
AU2016332725A1
(en)
|
2015-09-29 |
2018-03-22 |
Celgene Corporation |
PD-1 binding proteins and methods of use thereof
|
WO2017055322A1
(en)
|
2015-09-29 |
2017-04-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for quantifying the population of neutrophils in a tissue sample
|
EP3356551B1
(en)
|
2015-09-29 |
2020-09-02 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for determining the metabolic status of b-lymphomas
|
WO2017055327A1
(en)
|
2015-09-29 |
2017-04-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for quantifying the population of endothelial cells in a tissue sample
|
WO2017055319A1
(en)
|
2015-09-29 |
2017-04-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for quantifying the population of b cells in a tissue sample
|
WO2017055326A1
(en)
|
2015-09-29 |
2017-04-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for quantifying the population of myeloid dendritic cells in a tissue sample
|
WO2017055321A1
(en)
|
2015-09-29 |
2017-04-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for quantifying the population of fibroblasts in a tissue sample
|
WO2017055320A1
(en)
|
2015-09-29 |
2017-04-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for quantifying the population of cytotoxic lymphocytes in a tissue sample
|
WO2017059397A1
(en)
|
2015-10-01 |
2017-04-06 |
Whitehead Institute For Biomedical Research |
Labeling of antibodies
|
US20190054090A1
(en)
|
2015-10-01 |
2019-02-21 |
Gilead Sciences, Inc. |
Combination of a btk inhibitor and a checkpoint inhibitor for treating cancers
|
LT3356411T
(lt)
|
2015-10-02 |
2021-09-10 |
F. Hoffmann-La Roche Ag |
Bispecifiniai antikūnai, specifiniai pd1 ir tim3
|
AU2016329251B2
(en)
|
2015-10-02 |
2023-02-02 |
F. Hoffmann-La Roche Ag |
Anti-PD1 antibodies and methods of use
|
MX2018004177A
(es)
*
|
2015-10-08 |
2018-09-11 |
Macrogenics Inc |
Terapia de combinacion para el tratamiento de cancer.
|
WO2017060397A1
(en)
|
2015-10-09 |
2017-04-13 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting the survival time of subjects suffering from melanoma metastases
|
US11207393B2
(en)
|
2015-10-16 |
2021-12-28 |
President And Fellows Of Harvard College |
Regulatory T cell PD-1 modulation for regulating T cell effector immune responses
|
EP3365062A4
(en)
|
2015-10-19 |
2019-07-17 |
Cold Genesys, Inc. |
METHODS OF TREATING SOLID OR LYMPHATIC TUMORS BY POLYTHERAPY
|
KR20180066236A
(ko)
|
2015-10-22 |
2018-06-18 |
조운스 테라퓨틱스, 인크. |
Icos 발현을 계측하기 위한 유전자 특질
|
CN105238762A
(zh)
*
|
2015-10-26 |
2016-01-13 |
无锡傲锐东源生物科技有限公司 |
抗pd-1蛋白单克隆抗体杂交瘤细胞及其产生的抗pd-1单克隆抗体和应用
|
MA44334A
(fr)
|
2015-10-29 |
2018-09-05 |
Novartis Ag |
Conjugués d'anticorps comprenant un agoniste du récepteur de type toll
|
CN106632674B
(zh)
*
|
2015-10-30 |
2018-11-16 |
泽达生物医药有限公司 |
一种抗pd-1单克隆抗体、其药物组合物及其用途
|
EA201891106A1
(ru)
|
2015-11-02 |
2018-12-28 |
Файв Прайм Терапьютикс, Инк. |
Полипептиды внеклеточного домена cd80 и их применение в лечении рака
|
CN108473584B
(zh)
|
2015-11-03 |
2022-01-14 |
詹森生物科技公司 |
特异性结合pd-1和tim-3的抗体及其用途
|
US11702477B2
(en)
|
2015-11-06 |
2023-07-18 |
Orionis Biosciences BV |
Bi-functional chimeric proteins and uses thereof
|
KR20180071386A
(ko)
|
2015-11-18 |
2018-06-27 |
브리스톨-마이어스 스큅 컴퍼니 |
항-pd-1 항체 및 항-ctla-4 항체의 조합물을 사용하는 폐암의 치료
|
TWI791422B
(zh)
|
2015-11-23 |
2023-02-11 |
美商戊瑞治療有限公司 |
用於癌症治療之單獨fgfr2抑制劑或與免疫刺激劑組合
|
CA3007233A1
(en)
|
2015-12-02 |
2017-06-08 |
Agenus Inc. |
Antibodies and methods of use thereof
|
KR20180085793A
(ko)
*
|
2015-12-02 |
2018-07-27 |
주식회사 에스티큐브 |
글리코실화된 pd-1에 대해 특이적인 항체 및 이의 사용 방법
|
RU2020113165A
(ru)
|
2015-12-03 |
2020-06-09 |
Глэксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед |
Циклические пуриновые динуклеотиды в качестве модуляторов sting
|
WO2017098421A1
(en)
|
2015-12-08 |
2017-06-15 |
Glaxosmithkline Intellectual Property Development Limited |
Benzothiadiazine compounds
|
CN105837692A
(zh)
*
|
2015-12-10 |
2016-08-10 |
苏州佰通生物科技有限公司 |
一种阻断免疫检测点的嵌合抗原受体及其应用
|
CR20180318A
(es)
|
2015-12-14 |
2018-09-19 |
Macrogenics Inc |
Moléculas biespecíficas que tienen inmunorreactividad con pd-1 y ctla-4, y métodos de uso de las mismas
|
AU2016370648B2
(en)
|
2015-12-15 |
2023-03-09 |
OncoC4, Inc. |
Chimeric and humanized anti-human CTLA4 monoclonal antibodies and uses thereof
|
WO2017106062A1
(en)
|
2015-12-15 |
2017-06-22 |
Merck Sharp & Dohme Corp. |
Novel compounds as indoleamine 2,3-dioxygenase inhibitors
|
KR20180088907A
(ko)
|
2015-12-17 |
2018-08-07 |
노파르티스 아게 |
Pd-1에 대한 항체 분자 및 그의 용도
|
US10392442B2
(en)
|
2015-12-17 |
2019-08-27 |
Bristol-Myers Squibb Company |
Use of anti-PD-1 antibody in combination with anti-CD27 antibody in cancer treatment
|
CN109069623A
(zh)
|
2015-12-18 |
2018-12-21 |
诺华股份有限公司 |
靶向CD32b的抗体及其使用方法
|
JP7082055B2
(ja)
|
2015-12-22 |
2022-06-07 |
ノバルティス アーゲー |
抗癌治療における組み合わせ使用のためのメソテリンキメラ抗原受容体(car)およびpd-l1阻害剤に対する抗体
|
MX2018007774A
(es)
|
2015-12-22 |
2018-11-09 |
Incyte Corp |
Compuestos heterociclicos como inmunomoduladores.
|
PL3394103T3
(pl)
|
2015-12-22 |
2023-11-20 |
Regeneron Pharmaceuticals, Inc. |
Skojarzenie przeciwciał anty-pd-1 i przeciwciał dwuswoistych anty-cd20/anty-cd3 do leczenia nowotworów
|
CN105669864B
(zh)
*
|
2015-12-23 |
2018-10-16 |
杭州尚健生物技术有限公司 |
抗人程序性死亡受体1抗体及其制备方法和用途
|
EP3400443B1
(en)
|
2016-01-04 |
2020-09-16 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of pd-1 and tim-3 as a measure for cd8+ cells in predicting and treating renal cell carcinoma
|
CN115252792A
(zh)
|
2016-01-07 |
2022-11-01 |
博笛生物科技有限公司 |
用于治疗肿瘤的抗-egfr组合
|
CN115350279A
(zh)
|
2016-01-07 |
2022-11-18 |
博笛生物科技有限公司 |
用于治疗肿瘤的抗-her2组合
|
CN106943596A
(zh)
|
2016-01-07 |
2017-07-14 |
博笛生物科技(北京)有限公司 |
用于治疗肿瘤的抗-cd20组合
|
CN108712904B
(zh)
|
2016-01-08 |
2022-08-02 |
细胞基因公司 |
2-(4-氯苯基)-n-((2-(2,6-二氧代哌啶-3-基)-1-氧代异吲哚啉-5-基)甲基)-2,2-二氟乙酰胺的固体形式以及其药物组合物和用途
|
ES2956767T3
(es)
|
2016-01-08 |
2023-12-27 |
Celgene Corp |
Formulaciones de 2-(4-clorofenil)-N-((2-(2,6-dioxopiperidin-3-il)-1-oxoisoindolin-5-il)metil)-2,2-difluoroacetamida
|
HUE051231T2
(hu)
|
2016-01-08 |
2021-03-01 |
Celgene Corp |
Antiproliferatív vegyületek, és ezek gyógyszerészeti összetételei és alkalmazásai
|
AU2017208133B2
(en)
|
2016-01-11 |
2023-12-21 |
Universitat Zurich |
Immune-stimulating humanized monoclonal antibodies against human interleukin-2, and fusion proteins thereof
|
CA3012075A1
(en)
|
2016-01-22 |
2017-07-27 |
MabQuest SA |
Immunological reagents
|
US11214617B2
(en)
|
2016-01-22 |
2022-01-04 |
MabQuest SA |
Immunological reagents
|
EP4035681A1
(en)
|
2016-01-28 |
2022-08-03 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Methods and pharmaceutical composition for the treatment of cancer
|
ES2924741T3
(es)
|
2016-01-28 |
2022-10-10 |
Inst Nat Sante Rech Med |
Métodos para incrementar la potencia de los inhibidores del punto de control inmunitario
|
WO2017129763A1
(en)
|
2016-01-28 |
2017-08-03 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for the treatment of signet ring cell gastric cancer
|
WO2017133175A1
(en)
*
|
2016-02-04 |
2017-08-10 |
Nanjing Legend Biotech Co., Ltd. |
Engineered mammalian cells for cancer therapy
|
CN109071632B
(zh)
|
2016-02-05 |
2022-12-30 |
奥里尼斯生物科学私人有限公司 |
靶向性治疗剂及其用途
|
US11752238B2
(en)
|
2016-02-06 |
2023-09-12 |
President And Fellows Of Harvard College |
Recapitulating the hematopoietic niche to reconstitute immunity
|
IL260933B2
(en)
|
2016-02-08 |
2023-04-01 |
Beyondspring Pharmaceuticals Inc |
Preparations containing tocorsol or its analogues
|
TWI756204B
(zh)
|
2016-02-12 |
2022-03-01 |
比利時商楊森製藥公司 |
抗vista抗體及片段、其用途及鑑定其之方法
|
RU2018131123A
(ru)
|
2016-02-17 |
2020-03-17 |
Новартис Аг |
Антитела к tgf-бета2
|
US9845325B2
(en)
|
2016-02-19 |
2017-12-19 |
Novartis Ag |
Tetracyclic pyridone compounds as antivirals
|
MX2018010295A
(es)
|
2016-02-26 |
2019-06-06 |
Inst Nat Sante Rech Med |
Anticuerpos que tienen especificidad para atenuador de linfocitos b y t (btla) y usos de los mismos.
|
CN109476731A
(zh)
|
2016-02-29 |
2019-03-15 |
基础医药有限公司 |
治疗癌症的方法
|
KR20180118175A
(ko)
|
2016-03-04 |
2018-10-30 |
노파르티스 아게 |
다중 키메라 항원 수용체 (car) 분자를 발현하는 세포 및 그에 따른 용도
|
US10143746B2
(en)
|
2016-03-04 |
2018-12-04 |
Bristol-Myers Squibb Company |
Immunomodulators
|
WO2017155981A1
(en)
|
2016-03-07 |
2017-09-14 |
Massachusetts Institute Of Technology |
Protein-chaperoned t-cell vaccines
|
WO2017156349A1
(en)
|
2016-03-10 |
2017-09-14 |
Cold Genesys, Inc. |
Methods of treating solid or lymphatic tumors by combination therapy
|
WO2017153952A1
(en)
|
2016-03-10 |
2017-09-14 |
Glaxosmithkline Intellectual Property Development Limited |
5-sulfamoyl-2-hydroxybenzamide derivatives
|
WO2017160599A1
(en)
|
2016-03-14 |
2017-09-21 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Use of cd300b antagonists to treat sepsis and septic shock
|
EP3429693B1
(en)
|
2016-03-15 |
2023-08-23 |
Mersana Therapeutics, Inc. |
Napi2b-targeted antibody-drug conjugates and methods of use thereof
|
WO2017160975A1
(en)
*
|
2016-03-16 |
2017-09-21 |
Bristol-Myers Squibb Company |
Methods of diagnosing and treating lupus
|
US20210309965A1
(en)
|
2016-03-21 |
2021-10-07 |
Dana-Farber Cancer Institute, Inc. |
T-cell exhaustion state-specific gene expression regulators and uses thereof
|
EP3432924A1
(en)
|
2016-03-23 |
2019-01-30 |
Novartis AG |
Cell secreted minibodies and uses thereof
|
WO2017165742A1
(en)
|
2016-03-24 |
2017-09-28 |
Millennium Pharmaceuticals, Inc. |
Methods of treating gastrointestinal immune-related adverse events in anti-ctla4 anti-pd-1 combination treatments
|
WO2017165778A1
(en)
|
2016-03-24 |
2017-09-28 |
Millennium Pharmaceuticals, Inc. |
Methods of treating gastrointestinal immune-related adverse events in immune oncology treatments
|
ES2962269T3
(es)
|
2016-03-24 |
2024-03-18 |
Novartis Ag |
Análogos de nucleósidos alquinil como inhibidores del rinovirus humano
|
EP3225253A1
(en)
|
2016-04-01 |
2017-10-04 |
Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts |
Cancer therapy with an oncolytic virus combined with a checkpoint inhibitor
|
WO2017173334A1
(en)
|
2016-04-01 |
2017-10-05 |
Checkmate Pharmaceuticals, Inc. |
Fc receptor-mediated drug delivery
|
CN107286242B
(zh)
*
|
2016-04-01 |
2019-03-22 |
中山康方生物医药有限公司 |
抗pd-1的单克隆抗体
|
US10358463B2
(en)
|
2016-04-05 |
2019-07-23 |
Bristol-Myers Squibb Company |
Immunomodulators
|
WO2017176925A1
(en)
|
2016-04-05 |
2017-10-12 |
Bristol-Myers Squibb Company |
Cytokine profiling analysis for predicting prognosis of a patient in need of an anti-cancer treatment
|
JP2019510802A
(ja)
|
2016-04-07 |
2019-04-18 |
グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited |
タンパク質調節物質として有用な複素環アミド
|
CN113549110A
(zh)
|
2016-04-07 |
2021-10-26 |
葛兰素史密斯克莱知识产权发展有限公司 |
用作蛋白质调节剂的杂环酰胺
|
US20190218515A1
(en)
|
2016-04-13 |
2019-07-18 |
Vivia Biotech, S.L. |
Ex vivo bite-activated t cells
|
SG11201808633RA
(en)
|
2016-04-15 |
2018-10-30 |
Immunext Inc |
Anti-human vista antibodies and use thereof
|
US20190298824A1
(en)
|
2016-05-04 |
2019-10-03 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Serv |
Albumin-binding immunomodulatory compositions and methods of use thereof
|
CR20180521A
(es)
|
2016-05-05 |
2019-01-15 |
Glaxosmithkline Ip No 2 Ltd |
Inhibidores del potenciador del homólogo zeste 2
|
EP3243832A1
(en)
|
2016-05-13 |
2017-11-15 |
F. Hoffmann-La Roche AG |
Antigen binding molecules comprising a tnf family ligand trimer and pd1 binding moiety
|
TWI786044B
(zh)
|
2016-05-13 |
2022-12-11 |
美商再生元醫藥公司 |
藉由投予pd-1抑制劑治療皮膚癌之方法
|
WO2017194782A2
(en)
|
2016-05-13 |
2017-11-16 |
Orionis Biosciences Nv |
Therapeutic targeting of non-cellular structures
|
US11236141B2
(en)
|
2016-05-13 |
2022-02-01 |
Orionis Biosciences BV |
Targeted mutant interferon-beta and uses thereof
|
KR102419412B1
(ko)
|
2016-05-18 |
2022-07-12 |
베링거 인겔하임 인터내셔날 게엠베하 |
암 치료용 항-pd1 및 항-lag3 항체
|
CN105968200B
(zh)
|
2016-05-20 |
2019-03-15 |
瑞阳(苏州)生物科技有限公司 |
抗人pd-l1人源化单克隆抗体及其应用
|
US11623958B2
(en)
|
2016-05-20 |
2023-04-11 |
Harpoon Therapeutics, Inc. |
Single chain variable fragment CD3 binding proteins
|
US10688104B2
(en)
|
2016-05-20 |
2020-06-23 |
Eli Lilly And Company |
Combination therapy with Notch and PD-1 or PD-L1 inhibitors
|
EP3463452A1
(en)
|
2016-05-24 |
2019-04-10 |
Institut National de la Sante et de la Recherche Medicale (INSERM) |
Methods and pharmaceutical compositions for the treatment of non small cell lung cancer (nsclc) that coexists with chronic obstructive pulmonary disease (copd)
|
CN106008714B
(zh)
*
|
2016-05-24 |
2019-03-15 |
瑞阳(苏州)生物科技有限公司 |
抗人pd-1人源化单克隆抗体及其应用
|
US11458194B2
(en)
|
2016-05-25 |
2022-10-04 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Methods and compositions for treating cancers
|
KR102366813B1
(ko)
|
2016-05-27 |
2022-02-24 |
아게누스 인코포레이티드 |
항-tim-3 항체 및 이의 사용 방법
|
LT3463457T
(lt)
|
2016-06-02 |
2023-09-11 |
Bristol-Myers Squibb Company |
Pd-1 blokada su nivolumabu gydant atsparią hodžkino limfomą
|
EP4248989A3
(en)
|
2016-06-02 |
2023-12-27 |
Bristol-Myers Squibb Company |
Use of an anti-pd-1 antibody in combination with an anti-cd30 antibody in lymphoma treatment
|
CA3026172A1
(en)
|
2016-06-02 |
2017-12-07 |
Ultimovacs As |
A vaccine in combination with an immune checkpoint inhibitor for use in treating cancer
|
JP2019517511A
(ja)
|
2016-06-03 |
2019-06-24 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
腫瘍を処置する方法において使用するための抗pd−1抗体
|
EP3463454A1
(en)
|
2016-06-03 |
2019-04-10 |
Bristol-Myers Squibb Company |
Anti-pd-1 antibody for use in a method of treatment of recurrent small cell lung cancer
|
EP3988570A1
(en)
|
2016-06-03 |
2022-04-27 |
Bristol-Myers Squibb Company |
Use of anti-pd-1 antibody in the treatment of patients with colorectal cancer
|
EP3463337A4
(en)
|
2016-06-06 |
2020-02-12 |
Beyondspring Pharmaceuticals, Inc. |
COMPOSITION AND METHOD FOR REDUCING NEUTROPENIA
|
US10851053B2
(en)
|
2016-06-08 |
2020-12-01 |
Glaxosmithkline Intellectual Property Development Limited |
Chemical compounds
|
ES2913929T3
(es)
|
2016-06-08 |
2022-06-06 |
Glaxosmithkline Ip Dev Ltd |
Compuestos químicos como inhibidores de la ruta de ATF4
|
US11472856B2
(en)
|
2016-06-13 |
2022-10-18 |
Torque Therapeutics, Inc. |
Methods and compositions for promoting immune cell function
|
US10787518B2
(en)
*
|
2016-06-14 |
2020-09-29 |
Xencor, Inc. |
Bispecific checkpoint inhibitor antibodies
|
AU2017283768B2
(en)
|
2016-06-14 |
2019-05-23 |
Novartis Ag |
Crystalline form of (R)-4-(5-(cyclopropylethynyl)isoxazol-3-yl)-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide as an antibacterial agent
|
WO2017216686A1
(en)
|
2016-06-16 |
2017-12-21 |
Novartis Ag |
8,9-fused 2-oxo-6,7-dihydropyrido-isoquinoline compounds as antivirals
|
WO2017216685A1
(en)
|
2016-06-16 |
2017-12-21 |
Novartis Ag |
Pentacyclic pyridone compounds as antivirals
|
TWI784957B
(zh)
|
2016-06-20 |
2022-12-01 |
英商克馬伯有限公司 |
免疫細胞介素
|
IL263825B
(en)
|
2016-06-20 |
2022-08-01 |
Incyte Corp |
Heterocyclic compounds as immunomodulators
|
EP3474856B1
(en)
|
2016-06-24 |
2022-09-14 |
Infinity Pharmaceuticals, Inc. |
Combination therapies
|
AU2017293423B2
(en)
|
2016-07-05 |
2023-05-25 |
Beigene, Ltd. |
Combination of a PD-1 antagonist and a RAF inhibitor for treating cancer
|
US11098077B2
(en)
|
2016-07-05 |
2021-08-24 |
Chinook Therapeutics, Inc. |
Locked nucleic acid cyclic dinucleotide compounds and uses thereof
|
CR20190063A
(es)
|
2016-07-12 |
2019-05-27 |
Revolution Medicines Inc |
3-metil pirazinas 2,5-disustituídas y 3-metil pirazinas 2,5,6-trisustituídas como inhibidores alostéricos de shp2
|
WO2018011166A2
(en)
|
2016-07-12 |
2018-01-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for quantifying the population of myeloid dendritic cells in a tissue sample
|
JP2019522486A
(ja)
|
2016-07-13 |
2019-08-15 |
プレジデント アンド フェローズ オブ ハーバード カレッジ |
抗原提示細胞模倣足場およびそれを作製および使用するための方法
|
WO2018017708A1
(en)
|
2016-07-20 |
2018-01-25 |
University Of Utah Research Foundation |
Cd229 car t cells and methods of use thereof
|
AU2017300123A1
(en)
|
2016-07-20 |
2019-01-31 |
Glaxosmithkline Intellectual Property Development Limited |
Isoquinoline derivatives as PERK inhibitors
|
BR112019001570A2
(pt)
|
2016-07-28 |
2019-07-09 |
Novartis Ag |
terapias de combinação de receptores de antígeno quiméricos e inibidores de pd-1
|
CN109562282A
(zh)
|
2016-07-29 |
2019-04-02 |
伊莱利利公司 |
用于治疗癌症的使用merestinib和抗-pd-l1或抗-pd-1抑制剂的组合疗法
|
JP2019527236A
(ja)
|
2016-08-01 |
2019-09-26 |
モレキュラー テンプレーツ,インコーポレイティド |
癌を治療するための免疫調節剤と組み合わせた低酸素活性化型プロドラッグの投与
|
WO2018025221A1
(en)
|
2016-08-04 |
2018-02-08 |
Glaxosmithkline Intellectual Property Development Limited |
Anti-icos and anti-pd-1 antibody combination therapy
|
WO2018027524A1
(en)
|
2016-08-09 |
2018-02-15 |
Innovent Biologics (Suzhou) Co., Ltd. |
Pd-1 antibody formulation
|
WO2018029336A1
(en)
|
2016-08-12 |
2018-02-15 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for determining whether a subject was administered with an activator of the ppar beta/delta pathway.
|
WO2018033135A1
(en)
|
2016-08-19 |
2018-02-22 |
Beigene, Ltd. |
Use of a combination comprising a btk inhibitor for treating cancers
|
EP3500672A4
(en)
|
2016-08-22 |
2020-05-20 |
Twist Bioscience Corporation |
NOVO SYNTHESIZED NUCLEIC ACID BANKS
|
WO2018035710A1
(en)
|
2016-08-23 |
2018-03-01 |
Akeso Biopharma, Inc. |
Anti-ctla4 antibodies
|
CN106977602B
(zh)
*
|
2016-08-23 |
2018-09-25 |
中山康方生物医药有限公司 |
一种抗pd1单克隆抗体、其药物组合物及其用途
|
CN106967172B
(zh)
|
2016-08-23 |
2019-01-08 |
康方药业有限公司 |
抗ctla4-抗pd-1 双功能抗体、其药物组合物及其用途
|
EP4342978A2
(en)
|
2016-09-01 |
2024-03-27 |
Chimera Bioengineering Inc. |
Gold optimized car t-cells
|
WO2018047109A1
(en)
|
2016-09-09 |
2018-03-15 |
Novartis Ag |
Polycyclic pyridone compounds as antivirals
|
US20190218294A1
(en)
|
2016-09-09 |
2019-07-18 |
Bristol-Myers Squibb Company |
Use of an anti-pd-1 antibody in combination with an anti-mesothelin antibody in cancer treatment
|
US20190247399A1
(en)
|
2016-09-09 |
2019-08-15 |
Tg Therapeutics, Inc. |
Combination of an anti-cd20 antibody, pi3 kinase-delta inhibitor, and anti-pd-1 or anti-pd-l1 antibody for treating hematological cancers
|
WO2018046738A1
(en)
|
2016-09-12 |
2018-03-15 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting the survival time of patients suffering from cancer
|
WO2018046736A1
(en)
|
2016-09-12 |
2018-03-15 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting the survival time of patients suffering from cancer
|
EP3778643A1
(en)
|
2016-09-14 |
2021-02-17 |
AbbVie Biotherapeutics Inc. |
Pharmaceutical uses of anti-pd-1(cd279) antibodies
|
JP2019533645A
(ja)
|
2016-09-16 |
2019-11-21 |
ザ・ジョンズ・ホプキンス・ユニバーシティー |
標的組織および細胞内送達のための増大した粘膜浸透のタンパク質ナノケージ
|
CN109952317A
(zh)
|
2016-09-19 |
2019-06-28 |
细胞基因公司 |
使用pd-1结合蛋白治疗免疫病症的方法
|
JP2019534859A
(ja)
|
2016-09-19 |
2019-12-05 |
セルジーン コーポレイション |
Pd−1結合タンパク質を使用して白斑を治療する方法
|
US10417457B2
(en)
|
2016-09-21 |
2019-09-17 |
Twist Bioscience Corporation |
Nucleic acid based data storage
|
EP3515478B1
(en)
|
2016-09-21 |
2024-02-28 |
Nextcure, Inc. |
Antibodies for siglec-15 and methods of use thereof
|
AU2017332161A1
(en)
|
2016-09-21 |
2019-04-04 |
The United States Government As Represented By The Department Of Veterans Affairs |
Chimeric antigen receptor (car) that targets chemokine receptor CCR4 and its use
|
US20200016177A1
(en)
|
2016-09-22 |
2020-01-16 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Methods and pharmaceutical compositions for reprograming immune environment in a subject in need thereof
|
EP3515936A1
(en)
|
2016-09-23 |
2019-07-31 |
Elstar Therapeutics, Inc. |
Multispecific antibody molecules comprising lambda and kappa light chains
|
JOP20190061A1
(ar)
|
2016-09-28 |
2019-03-26 |
Novartis Ag |
مثبطات بيتا-لاكتاماز
|
EP3523287B1
(en)
|
2016-10-04 |
2021-09-01 |
Merck Sharp & Dohme Corp. |
Benzo[b]thiophene compounds as sting agonists
|
CN109843324A
(zh)
|
2016-10-06 |
2019-06-04 |
辉瑞公司 |
用于治疗癌症的avelumab用药方案
|
US10525083B2
(en)
|
2016-10-07 |
2020-01-07 |
Novartis Ag |
Nucleic acid molecules encoding chimeric antigen receptors comprising a CD20 binding domain
|
IL265800B2
(en)
|
2016-10-11 |
2023-10-01 |
Agenus Inc |
Anti-LAG-3 antibodies and methods of using them
|
WO2018071576A1
(en)
|
2016-10-14 |
2018-04-19 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Treatment of tumors by inhibition of cd300f
|
US20190263927A1
(en)
|
2016-10-14 |
2019-08-29 |
Merck Sharp & Dohme Corp. |
Combination of a pd-1 antagonist and eribulin for treating urothelial cancer
|
WO2018073753A1
(en)
|
2016-10-18 |
2018-04-26 |
Novartis Ag |
Fused tetracyclic pyridone compounds as antivirals
|
WO2018075447A1
(en)
|
2016-10-19 |
2018-04-26 |
The Trustees Of Columbia University In The City Of New York |
Combination of braf inhibitor, talimogene laherparepvec, and immune checkpoint inhibitor for use in the treatment cancer (melanoma)
|
CN110114368A
(zh)
|
2016-10-24 |
2019-08-09 |
奥睿尼斯生物科学公司 |
靶向突变干扰素-γ及其用途
|
US20190315865A1
(en)
|
2016-10-28 |
2019-10-17 |
Bristol-Myers Squibb Company |
Methods of treating urothelial carcinoma using an anti-pd-1 antibody
|
SG10201913306WA
(en)
|
2016-11-01 |
2020-02-27 |
Anaptysbio Inc |
Antibodies directed against programmed death- 1 (pd-1)
|
TW201829462A
(zh)
|
2016-11-02 |
2018-08-16 |
英商葛蘭素史克智慧財產(第二)有限公司 |
結合蛋白
|
BR112019008426A2
(pt)
|
2016-11-02 |
2019-09-03 |
Engmab Sarl |
anticorpo biespecífico contra bcma e cd3 e um fármaco imunológico para uso combinado no tratamento de mieloma múltiplo
|
CA3042679A1
(en)
|
2016-11-03 |
2018-05-11 |
Bristol-Myers Squibb Company |
Activatable anti-ctla-4 antibodies and uses thereof
|
US10342785B2
(en)
|
2016-11-04 |
2019-07-09 |
Askat Inc. |
Use of EP4 receptor antagonists for the treatment of NASH-associated liver cancer
|
WO2018085750A2
(en)
|
2016-11-07 |
2018-05-11 |
Bristol-Myers Squibb Company |
Immunomodulators
|
IT201600111877A1
(it)
*
|
2016-11-07 |
2018-05-07 |
Biouniversa Srl |
Anti-BAG3 antibodies in combination with inhibitors of immune check-point for therapeutic use
|
US20190345500A1
(en)
|
2016-11-14 |
2019-11-14 |
|Nserm (Institut National De La Santé Et De La Recherche Médicale) |
Methods and pharmaceutical compositions for modulating stem cells proliferation or differentiation
|
US11279694B2
(en)
|
2016-11-18 |
2022-03-22 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Alvocidib prodrugs and their use as protein kinase inhibitors
|
US20190365788A1
(en)
|
2016-11-21 |
2019-12-05 |
Idenix Pharmaceuticals Llc |
Cyclic phosphate substituted nucleoside derivatives for the treatment of liver diseases
|
US11135307B2
(en)
|
2016-11-23 |
2021-10-05 |
Mersana Therapeutics, Inc. |
Peptide-containing linkers for antibody-drug conjugates
|
WO2018101448A1
(en)
|
2016-11-30 |
2018-06-07 |
Kyowa Hakko Kirin Co., Ltd. |
Method of treating cancer using anti-ccr4 antibody and anti-pd-1 antibody
|
WO2018100535A1
(en)
|
2016-12-01 |
2018-06-07 |
Glaxosmithkline Intellectual Property Development Limited |
Combination therapy
|
EP3548069A1
(en)
|
2016-12-01 |
2019-10-09 |
GlaxoSmithKline Intellectual Property Development Limited |
Combination therapy
|
WO2018102786A1
(en)
|
2016-12-03 |
2018-06-07 |
Juno Therapeutics, Inc. |
Methods for modulation of car-t cells
|
KR102603681B1
(ko)
|
2016-12-07 |
2023-11-17 |
아게누스 인코포레이티드 |
항체 및 이의 사용방법
|
MA50949B1
(fr)
|
2016-12-07 |
2023-12-29 |
Memorial Sloan Kettering Cancer Center |
Anticorps anti-ctla-4 et leurs procédés d'utilisation
|
CA3047986A1
(en)
|
2016-12-22 |
2018-06-28 |
Incyte Corporation |
Benzooxazole derivatives as immunomodulators
|
CN110869052A
(zh)
|
2016-12-23 |
2020-03-06 |
维图生物制剂公司 |
癌症的治疗
|
CN110366564B
(zh)
|
2016-12-23 |
2023-07-07 |
瑞美德生物医药科技有限公司 |
使用与程序性死亡1(pd-1)结合的抗体的免疫疗法
|
WO2018122245A1
(en)
|
2016-12-28 |
2018-07-05 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods of predicting the survival time of patients suffering from cms3 colorectal cancer
|
WO2018122249A1
(en)
|
2016-12-28 |
2018-07-05 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting the survival time of patients suffering from a microsatellite stable colorectal cancer
|
US11633393B2
(en)
|
2017-01-06 |
2023-04-25 |
Beyondspring Pharmaceuticals, Inc. |
Tubulin binding compounds and therapeutic use thereof
|
EP3565560A4
(en)
|
2017-01-09 |
2021-01-13 |
Bioxcel Therapeutics, Inc. |
PREDICTIVE AND DIAGNOSTIC PROCEDURES FOR PROSTATE CANCER
|
JP7110206B6
(ja)
|
2017-01-09 |
2022-08-25 |
テサロ, インコーポレイテッド |
抗pd-1抗体を用いてがんを処置する方法
|
EP3568412A2
(en)
|
2017-01-13 |
2019-11-20 |
Agenus Inc. |
T cell receptors that bind to ny-eso-1 and methods of use thereof
|
WO2018134279A1
(en)
|
2017-01-18 |
2018-07-26 |
Pieris Pharmaceuticals Gmbh |
Novel fusion polypeptides specific for lag-3 and pd-1
|
CA3049047A1
(en)
*
|
2017-01-20 |
2018-07-26 |
Tayu Huaxia Biotech Medical Group Co., Ltd. |
Anti-pd-1 antibodies and uses thereof
|
WO2018134784A1
(en)
|
2017-01-20 |
2018-07-26 |
Novartis Ag |
Combination therapy for the treatment of cancer
|
KR20190110588A
(ko)
|
2017-01-23 |
2019-09-30 |
레볼루션 메디슨즈, 인크. |
알로스테릭 shp2 억제제로서의 피리딘 화합물
|
CA3051206A1
(en)
|
2017-01-23 |
2018-07-26 |
Revolution Medicines, Inc. |
Bicyclic compounds as allosteric shp2 inhibitors
|
US11555038B2
(en)
|
2017-01-25 |
2023-01-17 |
Beigene, Ltd. |
Crystalline forms of (S)-7-(1-(but-2-ynoyl)piperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide, preparation, and uses thereof
|
EP3573979A1
(en)
|
2017-01-27 |
2019-12-04 |
Celgene Corporation |
3-(1-oxo-4-((4-((3-oxomorpholino) methyl)benzyl)oxy)isoindolin-2-yl)piperidine-2,6-dione and isotopologues thereof
|
WO2018144764A1
(en)
|
2017-02-01 |
2018-08-09 |
Beyondspring Pharmaceuticals, Inc. |
Method of reducing neutropenia
|
JOP20190187A1
(ar)
|
2017-02-03 |
2019-08-01 |
Novartis Ag |
مترافقات عقار جسم مضاد لـ ccr7
|
EP3577133A1
(en)
|
2017-02-06 |
2019-12-11 |
Orionis Biosciences NV |
Targeted chimeric proteins and uses thereof
|
JP2020505955A
(ja)
|
2017-02-06 |
2020-02-27 |
オリオンズ バイオサイエンス インコーポレイテッド |
標的化改変型インターフェロン及びその使用
|
WO2018146148A1
(en)
|
2017-02-07 |
2018-08-16 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
A method for predicting the response to checkpoint blockade cancer immunotherapy
|
WO2018146128A1
(en)
|
2017-02-07 |
2018-08-16 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Detection of kit polymorphism for predicting the response to checkpoint blockade cancer immunotherapy
|
PL3579874T3
(pl)
|
2017-02-10 |
2022-02-28 |
Novartis Ag |
1-(4-amino-5-bromo-6-(1 h-pirazol-1-ilo)pirymidyn-2-ylo)-1 h-pirazol-4-ol i jego zastosowanie w leczeniu nowotworu złośliwego
|
WO2018150326A1
(en)
|
2017-02-15 |
2018-08-23 |
Glaxosmithkline Intellectual Property Development Limited |
Combination treatment for cancer
|
US20200291089A1
(en)
|
2017-02-16 |
2020-09-17 |
Elstar Therapeutics, Inc. |
Multifunctional molecules comprising a trimeric ligand and uses thereof
|
US11292842B2
(en)
|
2017-02-21 |
2022-04-05 |
Regeneron Pharmaceuticals, Inc. |
Anti-PD-1 antibodies for treatment of lung cancer
|
WO2018156777A1
(en)
*
|
2017-02-22 |
2018-08-30 |
Sutro Biopharma, Inc. |
Pd-1/tim-3 bi-specific antibodies, compositions thereof, and methods of making and using the same
|
EP3586255A4
(en)
|
2017-02-22 |
2021-03-31 |
Twist Bioscience Corporation |
NUCLEIC ACID-BASED DATA STORAGE
|
US11459394B2
(en)
|
2017-02-24 |
2022-10-04 |
Macrogenics, Inc. |
Bispecific binding molecules that are capable of binding CD137 and tumor antigens, and uses thereof
|
JP2020509009A
(ja)
|
2017-02-27 |
2020-03-26 |
グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited |
キナーゼ阻害剤としての複素環式アミド
|
US20180271996A1
(en)
|
2017-02-28 |
2018-09-27 |
Mersana Therapeutics, Inc. |
Combination therapies of her2-targeted antibody-drug conjugates
|
US11161905B2
(en)
|
2017-03-04 |
2021-11-02 |
Xiangtan Tenghua Bioscience |
Recombinant antibodies to programmed death 1 (PD-1) and uses thereof
|
WO2018163051A1
(en)
|
2017-03-06 |
2018-09-13 |
Novartis Ag |
Methods of treatment of cancer with reduced ubb expression
|
WO2018167778A1
(en)
|
2017-03-12 |
2018-09-20 |
Yeda Research And Development Co. Ltd. |
Methods of diagnosing and prognosing cancer
|
WO2018167780A1
(en)
|
2017-03-12 |
2018-09-20 |
Yeda Research And Development Co. Ltd. |
Methods of prognosing and treating cancer
|
CA3056392A1
(en)
|
2017-03-15 |
2018-09-20 |
Amgen Inc. |
Use of oncolytic viruses, alone or in combination with a checkpoint inhibitor, for the treatment of cancer
|
WO2018170169A1
(en)
|
2017-03-15 |
2018-09-20 |
Twist Bioscience Corporation |
Variant libraries of the immunological synapse and synthesis thereof
|
WO2018170288A1
(en)
|
2017-03-15 |
2018-09-20 |
Pandion Therapeutics, Inc. |
Targeted immunotolerance
|
US20210186982A1
(en)
|
2017-03-24 |
2021-06-24 |
Universite Nice Sophia Antipolis |
Methods and compositions for treating melanoma
|
US20200031944A1
(en)
|
2017-03-31 |
2020-01-30 |
Five Prime Therapeutics, Inc. |
Combination therapy for cancer using anti-gitr antibodies
|
KR20190133213A
(ko)
|
2017-03-31 |
2019-12-02 |
브리스톨-마이어스 스큅 컴퍼니 |
종양을 치료하는 방법
|
CN106987631A
(zh)
*
|
2017-04-01 |
2017-07-28 |
武汉赛云博生物科技有限公司 |
一种用于pd‑1/pd‑l1阻断治疗伴随诊断的免疫组测序技术
|
WO2018185618A1
(en)
|
2017-04-03 |
2018-10-11 |
Novartis Ag |
Anti-cdh6 antibody drug conjugates and anti-gitr antibody combinations and methods of treatment
|
CN110392692B
(zh)
|
2017-04-03 |
2023-07-21 |
豪夫迈·罗氏有限公司 |
抗pd-1抗体与突变体il-2或与il-15的免疫缀合物
|
KR102408873B1
(ko)
|
2017-04-05 |
2022-06-15 |
에프. 호프만-라 로슈 아게 |
Pd1 및 lag3에 특이적으로 결합하는 이중특이적 항체
|
US11603407B2
(en)
|
2017-04-06 |
2023-03-14 |
Regeneron Pharmaceuticals, Inc. |
Stable antibody formulation
|
TWI788340B
(zh)
|
2017-04-07 |
2023-01-01 |
美商必治妥美雅史谷比公司 |
抗icos促效劑抗體及其用途
|
TW201841942A
(zh)
|
2017-04-13 |
2018-12-01 |
美商艾吉納斯公司 |
抗cd137抗體及其使用方法
|
CN110573624A
(zh)
|
2017-04-14 |
2019-12-13 |
永恒生物科技股份有限公司 |
治疗膀胱癌的方法
|
CN108728444A
(zh)
|
2017-04-18 |
2018-11-02 |
长春华普生物技术股份有限公司 |
免疫调节性多核苷酸及其应用
|
EP3612517B1
(en)
|
2017-04-18 |
2022-03-02 |
Tempest Therapeutics, Inc. |
Bicyclic compounds and their use in the treatment of cancer
|
WO2018195283A1
(en)
|
2017-04-19 |
2018-10-25 |
Elstar Therapeutics, Inc. |
Multispecific molecules and uses thereof
|
CN106939049B
(zh)
*
|
2017-04-20 |
2019-10-01 |
苏州思坦维生物技术股份有限公司 |
拮抗抑制人pd-1抗原与其配体结合的单克隆抗体及其制备方法与应用
|
KR20190137911A
(ko)
|
2017-04-21 |
2019-12-11 |
신라젠(주) |
항암 백시니아 바이러스와 관문 저해제 병용 요법
|
AR111419A1
(es)
|
2017-04-27 |
2019-07-10 |
Novartis Ag |
Compuestos fusionados de indazol piridona como antivirales
|
CN108794467A
(zh)
|
2017-04-27 |
2018-11-13 |
博笛生物科技有限公司 |
2-氨基-喹啉衍生物
|
AR111651A1
(es)
|
2017-04-28 |
2019-08-07 |
Novartis Ag |
Conjugados de anticuerpos que comprenden agonistas del receptor de tipo toll y terapias de combinación
|
WO2018201051A1
(en)
|
2017-04-28 |
2018-11-01 |
Novartis Ag |
Bcma-targeting agent, and combination therapy with a gamma secretase inhibitor
|
EP3615055A1
(en)
|
2017-04-28 |
2020-03-04 |
Novartis AG |
Cells expressing a bcma-targeting chimeric antigen receptor, and combination therapy with a gamma secretase inhibitor
|
UY37695A
(es)
|
2017-04-28 |
2018-11-30 |
Novartis Ag |
Compuesto dinucleótido cíclico bis 2’-5’-rr-(3’f-a)(3’f-a) y usos del mismo
|
CA3059769A1
(en)
|
2017-04-28 |
2018-11-01 |
Elstar Therapeutics, Inc. |
Multispecific molecules comprising a non-immunoglobulin heterodimerization domain and uses thereof
|
MA50957A
(fr)
|
2017-05-01 |
2020-10-14 |
Agenus Inc |
Anticorps anti-tigit et leurs méthodes d'utilisation
|
EP3618871A4
(en)
|
2017-05-02 |
2021-01-06 |
Merck Sharp & Dohme Corp. |
ANTI-LAG3 ANTIBODIES ETCO-FORMULATIONS ANTI-LAG3 ANTIBODIES AND ANTI-PD-1 ANTIBODIES
|
JOP20190260A1
(ar)
|
2017-05-02 |
2019-10-31 |
Merck Sharp & Dohme |
صيغ ثابتة لأجسام مضادة لمستقبل الموت المبرمج 1 (pd-1) وطرق استخدامها
|
UY37718A
(es)
|
2017-05-05 |
2018-11-30 |
Novartis Ag |
2-quinolinonas triciclicas como agentes antibacteriales
|
KR102376863B1
(ko)
|
2017-05-12 |
2022-03-21 |
하푼 테라퓨틱스, 인크. |
메소텔린 결합 단백질
|
JOP20190256A1
(ar)
|
2017-05-12 |
2019-10-28 |
Icahn School Med Mount Sinai |
فيروسات داء نيوكاسل واستخداماتها
|
WO2018208667A1
(en)
|
2017-05-12 |
2018-11-15 |
Merck Sharp & Dohme Corp. |
Cyclic di-nucleotide compounds as sting agonists
|
EP3625260A1
(en)
|
2017-05-16 |
2020-03-25 |
Bristol-Myers Squibb Company |
Treatment of cancer with anti-gitr agonist antibodies
|
AR111760A1
(es)
|
2017-05-19 |
2019-08-14 |
Novartis Ag |
Compuestos y composiciones para el tratamiento de tumores sólidos mediante administración intratumoral
|
CN110662762A
(zh)
|
2017-05-24 |
2020-01-07 |
诺华股份有限公司 |
抗体细胞因子移植蛋白和用于治疗癌症的方法
|
WO2018215938A1
(en)
|
2017-05-24 |
2018-11-29 |
Novartis Ag |
Antibody-cytokine engrafted proteins and methods of use
|
WO2018215937A1
(en)
|
2017-05-24 |
2018-11-29 |
Novartis Ag |
Interleukin-7 antibody cytokine engrafted proteins and methods of use in the treatment of cancer
|
AU2018273914A1
(en)
|
2017-05-24 |
2019-11-14 |
Pandion Operations, Inc. |
Targeted immunotolerance
|
AR111960A1
(es)
|
2017-05-26 |
2019-09-04 |
Incyte Corp |
Formas cristalinas de un inhibidor de fgfr y procesos para su preparación
|
KR20200010500A
(ko)
|
2017-05-30 |
2020-01-30 |
브리스톨-마이어스 스큅 컴퍼니 |
항-lag-3 항체, pd-1 경로 억제제, 및 면역요법제의 조합을 포함하는 조성물
|
MX2019012076A
(es)
|
2017-05-30 |
2019-12-09 |
Bristol Myers Squibb Co |
Composiciones que comprenden un anticuerpo anti gen-3 de activacion del linfocito (lag-3) o un anticuerpo anti-lag-3 y un anticuerpo anti muerte celular programada 1 (pd-1) o anti ligando 1 de muerte celular programada (pd-l1).
|
EP3631454B1
(en)
|
2017-05-30 |
2023-09-13 |
Bristol-Myers Squibb Company |
Treatment of lag-3 positive tumors
|
WO2018222901A1
(en)
|
2017-05-31 |
2018-12-06 |
Elstar Therapeutics, Inc. |
Multispecific molecules that bind to myeloproliferative leukemia (mpl) protein and uses thereof
|
CN111051346A
(zh)
*
|
2017-05-31 |
2020-04-21 |
斯特库伯株式会社 |
使用免疫特异性结合btn1a1的抗体和分子治疗癌症的方法
|
JOP20190279A1
(ar)
|
2017-05-31 |
2019-11-28 |
Novartis Ag |
الصور البلورية من 5-برومو -2، 6-داي (1h-بيرازول -1-يل) بيريميدين -4- أمين وأملاح جديدة
|
US20200181274A1
(en)
|
2017-06-01 |
2020-06-11 |
Novartis Ag |
Bispecific antibodies that bind cd 123 cd3
|
WO2018223004A1
(en)
|
2017-06-01 |
2018-12-06 |
Xencor, Inc. |
Bispecific antibodies that bind cd20 and cd3
|
KR20200014363A
(ko)
|
2017-06-01 |
2020-02-10 |
브리스톨-마이어스 스큅 컴퍼니 |
항-pd-1 항체를 사용하여 종양을 치료하는 방법
|
US11559504B2
(en)
|
2017-06-02 |
2023-01-24 |
The Penn State Research Foundation |
Ceramide nanoliposomes, compositions and methods of using for immunotherapy
|
MX2019014268A
(es)
|
2017-06-02 |
2020-08-03 |
Juno Therapeutics Inc |
Artículos de manufactura y métodos para tratamiento usando terapia celular adoptiva.
|
US11542331B2
(en)
|
2017-06-06 |
2023-01-03 |
Stcube & Co., Inc. |
Methods of treating cancer using antibodies and molecules that bind to BTN1A1 or BTN1A1-ligands
|
WO2018225093A1
(en)
|
2017-06-07 |
2018-12-13 |
Glaxosmithkline Intellectual Property Development Limited |
Chemical compounds as atf4 pathway inhibitors
|
KR20200015717A
(ko)
|
2017-06-09 |
2020-02-12 |
프로비던스 헬스 앤드 서비시즈 - 오레곤 |
암 치료를 위한 인간 종양 반응성 t 세포의 확인을 위한 cd39 및 cd103의 활용
|
JP2020522555A
(ja)
|
2017-06-09 |
2020-07-30 |
グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited |
組み合わせ療法
|
WO2018231864A1
(en)
|
2017-06-12 |
2018-12-20 |
Twist Bioscience Corporation |
Methods for seamless nucleic acid assembly
|
AU2018284227A1
(en)
|
2017-06-12 |
2020-01-30 |
Twist Bioscience Corporation |
Methods for seamless nucleic acid assembly
|
WO2018229715A1
(en)
|
2017-06-16 |
2018-12-20 |
Novartis Ag |
Compositions comprising anti-cd32b antibodies and methods of use thereof
|
JP2020524157A
(ja)
|
2017-06-20 |
2020-08-13 |
アンスティテュート キュリー |
がん併用療法における使用のためのsuv39h1ヒストンメチルトランスフェラーゼの阻害剤
|
WO2018235056A1
(en)
|
2017-06-22 |
2018-12-27 |
Novartis Ag |
IL-1BETA BINDING ANTIBODIES FOR USE IN THE TREATMENT OF CANCER
|
BR112019027402A2
(pt)
|
2017-06-22 |
2020-07-07 |
Celgene Corporation |
tratamento de carcinoma hepatocelular caracterizado por infecção pelo vírus da hepatite b
|
US20200172628A1
(en)
|
2017-06-22 |
2020-06-04 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
US20190048072A1
(en)
|
2017-06-22 |
2019-02-14 |
Novartis Ag |
USE OF IL-1beta BINDING ANTIBODIES
|
US11312783B2
(en)
|
2017-06-22 |
2022-04-26 |
Novartis Ag |
Antibody molecules to CD73 and uses thereof
|
CA3067268A1
(en)
|
2017-06-23 |
2018-12-27 |
Birdie Biopharmaceuticals, Inc. |
Crystalline resiquimod monosulfate anhydrate and its preparation and uses
|
WO2018237153A1
(en)
|
2017-06-23 |
2018-12-27 |
Bristol-Myers Squibb Company |
IMMUNOMODULATORS ACTING AS PD-1 ANTAGONISTS
|
WO2019005635A2
(en)
*
|
2017-06-25 |
2019-01-03 |
Systimmune, Inc. |
ANTI-PD-1 ANTIBODIES AND METHODS OF PREPARATION AND USE
|
AU2018290532A1
(en)
|
2017-06-26 |
2019-11-21 |
Beigene, Ltd. |
Immunotherapy for hepatocellular carcinoma
|
WO2019006007A1
(en)
|
2017-06-27 |
2019-01-03 |
Novartis Ag |
POSOLOGICAL REGIMES FOR ANTI-TIM3 ANTIBODIES AND USES THEREOF
|
CA3067602A1
(en)
|
2017-06-29 |
2019-01-03 |
Juno Therapeutics, Inc. |
Mouse model for assessing toxicities associated with immunotherapies
|
KR20200020899A
(ko)
|
2017-06-30 |
2020-02-26 |
셀진 코포레이션 |
2-(4-클로로페닐)-n-((2-(2,6-디옥소피페리딘-3-일)-1-옥소이소인돌린-5-일)메틸)-2,2-디플루오로아세트아미드의 조성물 및 사용 방법
|
WO2019008506A1
(en)
|
2017-07-03 |
2019-01-10 |
Glaxosmithkline Intellectual Property Development Limited |
N- (3- (2- (4-CHLOROPHENOXY) ACETAMIDO) BICYCLO [1.1.1] PENTAN-1-YL) -2-CYCLOBUTANE-1-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS ATF4 INHIBITORS FOR THE TREATMENT OF CANCER AND OTHER DISEASES
|
CN110896634A
(zh)
|
2017-07-03 |
2020-03-20 |
葛兰素史密斯克莱知识产权发展有限公司 |
作为atf4抑制剂用于治疗癌症和其它疾病的2-(4-氯苯氧基)-n-((1-(2-(4-氯苯氧基)乙炔氮杂环丁烷-3-基)甲基)乙酰胺衍生物和相关化合物
|
US10357489B2
(en)
|
2017-07-10 |
2019-07-23 |
Celgene Corporation |
Antiproliferative compounds and methods of use thereof
|
EP3655542A1
(en)
|
2017-07-18 |
2020-05-27 |
Institut Gustave Roussy |
Method for assessing the response to pd-1/pdl-1 targeting drugs
|
CN111163798A
(zh)
|
2017-07-20 |
2020-05-15 |
诺华股份有限公司 |
用于抗lag-3抗体的给药方案及其用途
|
EP3658173A1
(en)
|
2017-07-25 |
2020-06-03 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for modulating monocytopoiesis
|
WO2019021208A1
(en)
|
2017-07-27 |
2019-01-31 |
Glaxosmithkline Intellectual Property Development Limited |
USEFUL INDAZOLE DERIVATIVES AS PERK INHIBITORS
|
KR20200033930A
(ko)
|
2017-07-28 |
2020-03-30 |
브리스톨-마이어스 스큅 컴퍼니 |
체크포인트 억제제에 대한 예측성 말초 혈액 바이오마커
|
EP3661499A4
(en)
|
2017-08-04 |
2021-04-21 |
Merck Sharp & Dohme Corp. |
COMBINATIONS OF PD-1 ANTAGONISTS AND BENZO [B]
|
JP2020530838A
(ja)
|
2017-08-04 |
2020-10-29 |
メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. |
がん治療のためのベンゾ[b]チオフェンSTINGアゴニスト
|
CN111094982A
(zh)
|
2017-08-28 |
2020-05-01 |
百时美施贵宝公司 |
用于治疗和诊断癌症的tim-3拮抗剂
|
AU2018326875A1
(en)
|
2017-09-04 |
2020-03-19 |
Agenus Inc. |
T cell receptors that bind to mixed lineage leukemia (MLL)-specific phosphopeptides and methods of use thereof
|
UY37866A
(es)
|
2017-09-07 |
2019-03-29 |
Glaxosmithkline Ip Dev Ltd |
Nuevos compuestos derivados de benzoimidazol sustituidos que reducen la proteína myc (c-myc) en las células e inhiben la histona acetiltransferasa de p300/cbp.
|
JP7356414B2
(ja)
|
2017-09-07 |
2023-10-04 |
レヴォリューション・メディスンズ,インコーポレイテッド |
がんを治療するためのshp2阻害剤組成物および方法
|
EP3679070A1
(en)
|
2017-09-07 |
2020-07-15 |
Augusta University Research Institute, Inc. |
Antibodies to programmed cell death protein 1
|
KR20200047706A
(ko)
|
2017-09-11 |
2020-05-07 |
트위스트 바이오사이언스 코포레이션 |
Gpcr 결합 단백질 및 이의 합성 방법
|
WO2019053617A1
(en)
|
2017-09-12 |
2019-03-21 |
Glaxosmithkline Intellectual Property Development Limited |
CHEMICAL COMPOUNDS
|
JP7196160B2
(ja)
|
2017-09-12 |
2022-12-26 |
スミトモ ファーマ オンコロジー, インコーポレイテッド |
Mcl-1阻害剤アルボシジブを用いた、bcl-2阻害剤に対して非感受性である癌の治療レジメン
|
WO2019057744A1
(en)
|
2017-09-19 |
2019-03-28 |
Institut Curie |
AROMATIC HYDROCARBON RECEPTOR AGONIST FOR USE IN ASSOCIATION TREATMENT AGAINST CANCER
|
CN109554349B
(zh)
*
|
2017-09-27 |
2022-06-24 |
亘喜生物科技(上海)有限公司 |
Pd-1基因表达沉默的工程化免疫细胞
|
WO2019061324A1
(en)
|
2017-09-29 |
2019-04-04 |
Curis Inc. |
CRYSTALLINE FORMS OF IMMUNOMODULATORS
|
JP7257393B2
(ja)
|
2017-10-03 |
2023-04-13 |
ブリストル-マイヤーズ スクイブ カンパニー |
免疫調節剤
|
WO2019069269A1
(en)
|
2017-10-05 |
2019-04-11 |
Glaxosmithkline Intellectual Property Development Limited |
INTERFERON GENE STIMULATOR MODULATORS USEFUL IN THE TREATMENT OF HIV
|
JP7291130B2
(ja)
|
2017-10-05 |
2023-06-14 |
グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッド |
インターフェロン遺伝子の刺激物質(sting)の調節物質
|
EP3694879A1
(en)
*
|
2017-10-10 |
2020-08-19 |
Numab Therapeutics AG |
Antibodies targeting pdl1 and methods of use thereof
|
EP3694841A1
(en)
|
2017-10-11 |
2020-08-19 |
Aurigene Discovery Technologies Limited |
Crystalline forms of 3-substituted 1,2,4-oxadiazole
|
KR20200070295A
(ko)
|
2017-10-12 |
2020-06-17 |
레볼루션 메디슨즈, 인크. |
알로스테릭 shp2 억제제로서의 피리딘, 피라진 및 트리아진 화합물
|
US20200239577A1
(en)
|
2017-10-15 |
2020-07-30 |
Bristol-Myers Squibb Company |
Methods of treating tumor
|
WO2019077062A1
(en)
|
2017-10-18 |
2019-04-25 |
Vivia Biotech, S.L. |
C-CELLS ACTIVATED BY BIT
|
SG11202003574TA
(en)
|
2017-10-20 |
2020-05-28 |
Twist Bioscience Corp |
Heated nanowells for polynucleotide synthesis
|
EP3700933A1
(en)
|
2017-10-25 |
2020-09-02 |
Novartis AG |
Antibodies targeting cd32b and methods of use thereof
|
WO2019089858A2
(en)
|
2017-11-01 |
2019-05-09 |
Juno Therapeutics, Inc. |
Methods of assessing or monitoring a response to a cell therapy
|
EP3703750A1
(en)
|
2017-11-01 |
2020-09-09 |
Juno Therapeutics, Inc. |
Chimeric antigen receptors specific for b-cell maturation antigen and encoding polynucleotides
|
US20210179607A1
(en)
|
2017-11-01 |
2021-06-17 |
Merck Sharp & Dohme Corp. |
Novel substituted tetrahydroquinolin compounds as indoleamine 2,3-dioxygenase (ido) inhibitors
|
SG11202003501XA
(en)
|
2017-11-01 |
2020-05-28 |
Juno Therapeutics Inc |
Antibodies and chimeric antigen receptors specific for b-cell maturation antigen
|
SG11202003625VA
(en)
|
2017-11-03 |
2020-05-28 |
Aurigene Discovery Tech Ltd |
Dual inhibitors of tim-3 and pd-1 pathways
|
BR112020008316A2
(pt)
|
2017-11-06 |
2020-10-20 |
Bristol-Myers Squibb Company |
métodos para o tratamento de um tumor
|
US11497735B2
(en)
|
2017-11-06 |
2022-11-15 |
Aurigene Discovery Technologies Limited |
Conjoint therapies for immunomodulation
|
CN111315398A
(zh)
|
2017-11-10 |
2020-06-19 |
阿尔莫生物科技股份有限公司 |
白介素-10与免疫检查点途径抑制剂的组合的组合物和使用方法
|
WO2019099294A1
(en)
|
2017-11-14 |
2019-05-23 |
Merck Sharp & Dohme Corp. |
Novel substituted biaryl compounds as indoleamine 2,3-dioxygenase (ido) inhibitors
|
US10647705B2
(en)
|
2017-11-14 |
2020-05-12 |
Merck Sharp & Dohme Corp. |
Substituted biaryl compounds as indoleamine 2,3-dioxygenase (IDO) inhibitors
|
WO2019099838A1
(en)
|
2017-11-16 |
2019-05-23 |
Novartis Ag |
Combination therapies
|
EP3710479A2
(en)
|
2017-11-17 |
2020-09-23 |
Merck Sharp & Dohme Corp. |
Antibodies specific for immunoglobulin-like transcript 3 (ilt3) and uses thereof
|
WO2019097479A1
(en)
|
2017-11-17 |
2019-05-23 |
Novartis Ag |
Novel dihydroisoxazole compounds and their use for the treatment of hepatitis b
|
CA3083158A1
(en)
|
2017-11-24 |
2019-05-31 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Methods and compositions for treating cancers
|
US11638760B2
(en)
|
2017-11-27 |
2023-05-02 |
Mersana Therapeutics, Inc. |
Pyrrolobenzodiazepine antibody conjugates
|
WO2019108795A1
(en)
|
2017-11-29 |
2019-06-06 |
Beigene Switzerland Gmbh |
Treatment of indolent or aggressive b-cell lymphomas using a combination comprising btk inhibitors
|
AU2018375738A1
(en)
|
2017-11-30 |
2020-06-11 |
Novartis Ag |
BCMA-targeting chimeric antigen receptor, and uses thereof
|
US10946068B2
(en)
|
2017-12-06 |
2021-03-16 |
Pandion Operations, Inc. |
IL-2 muteins and uses thereof
|
US10174092B1
(en)
|
2017-12-06 |
2019-01-08 |
Pandion Therapeutics, Inc. |
IL-2 muteins
|
EP3720881A1
(en)
|
2017-12-08 |
2020-10-14 |
Elstar Therapeutics, Inc. |
Multispecific molecules and uses thereof
|
US11946094B2
(en)
|
2017-12-10 |
2024-04-02 |
Augusta University Research Institute, Inc. |
Combination therapies and methods of use thereof
|
WO2019118909A1
(en)
|
2017-12-15 |
2019-06-20 |
Revolution Medicines, Inc. |
Polycyclic compounds as allosteric shp2 inhibitors
|
KR20200110745A
(ko)
|
2017-12-15 |
2020-09-25 |
주노 쎄러퓨티크스 인코퍼레이티드 |
항 - cct5 결합 분자 및 이의 사용 방법
|
WO2019123285A1
(en)
|
2017-12-20 |
2019-06-27 |
Novartis Ag |
Fused tricyclic pyrazolo-dihydropyrazinyl-pyridone compounds as antivirals
|
US11685761B2
(en)
|
2017-12-20 |
2023-06-27 |
Merck Sharp & Dohme Llc |
Cyclic di-nucleotide compounds as sting agonists
|
CN111757757A
(zh)
|
2017-12-21 |
2020-10-09 |
梅尔莎纳医疗公司 |
吡咯并苯并二氮呯抗体共轭物
|
CN109966487B
(zh)
*
|
2017-12-28 |
2023-08-25 |
上海复宏汉霖生物制药有限公司 |
一种包含抗pd-l1单克隆抗体的药物配制剂
|
WO2019134946A1
(en)
|
2018-01-04 |
2019-07-11 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma resistant
|
US11324774B2
(en)
|
2018-01-05 |
2022-05-10 |
Augusta University Research Institute, Inc. |
Compositions of oral alkaline salts and metabolic acid inducers and uses thereof
|
CN112218651A
(zh)
|
2018-01-08 |
2021-01-12 |
诺华公司 |
用于与嵌合抗原受体疗法组合的免疫增强rna
|
AU2019207812A1
(en)
|
2018-01-12 |
2020-07-23 |
Bristol-Myers Squibb Company |
Combination therapy with anti-IL-8 antibodies and anti-PD-1 antibodies for treating cancer
|
EP3740506A1
(en)
|
2018-01-16 |
2020-11-25 |
Bristol-Myers Squibb Company |
Methods of treating cancer with antibodies against tim3
|
JP2021511344A
(ja)
|
2018-01-22 |
2021-05-06 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
癌を治療する組成物および方法
|
US20210038559A1
(en)
|
2018-01-22 |
2021-02-11 |
Thomas Richard Gadek |
Cannabinoids and derivatives for promoting immunogenicity of tumor and infected cells
|
CN112566934A
(zh)
|
2018-01-23 |
2021-03-26 |
奈斯科尔公司 |
B7-h4抗体及其使用方法
|
CN112135614A
(zh)
|
2018-01-24 |
2020-12-25 |
大连万春布林医药有限公司 |
通过施用普那布林减少血小板减少症的组合物和方法
|
KR20200128014A
(ko)
|
2018-01-31 |
2020-11-11 |
셀진 코포레이션 |
입양 세포 요법 및 체크포인트 억제제를 이용한 병용 요법
|
EP3746480A1
(en)
|
2018-01-31 |
2020-12-09 |
F. Hoffmann-La Roche AG |
Bispecific antibodies comprising an antigen-binding site binding to lag3
|
US20210038659A1
(en)
|
2018-01-31 |
2021-02-11 |
Novartis Ag |
Combination therapy using a chimeric antigen receptor
|
US20200405806A1
(en)
|
2018-02-08 |
2020-12-31 |
Bristol-Myers Squibb Company |
Combination of a tetanus toxoid, anti-ox40 antibody and/or anti-pd-1 antibody to treat tumors
|
TWI804572B
(zh)
|
2018-02-09 |
2023-06-11 |
日商小野藥品工業股份有限公司 |
雙特異性抗體
|
NL2020422B1
(en)
|
2018-02-12 |
2019-08-19 |
Stichting Het Nederlands Kanker Inst Antoni Van Leeuwenhoek Ziekenhuis |
Methods for Predicting Treatment Outcome and/or for Selecting a Subject Suitable for Immune Checkpoint Therapy.
|
WO2019160956A1
(en)
|
2018-02-13 |
2019-08-22 |
Novartis Ag |
Chimeric antigen receptor therapy in combination with il-15r and il15
|
WO2019162325A1
(en)
|
2018-02-21 |
2019-08-29 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of sk1 as biomarker for predicting response to immunecheckpoint inhibitors
|
MA52422A
(fr)
|
2018-02-27 |
2021-01-06 |
Incyte Corp |
Imidazopyrimidines et triazolopyrimidines en tant qu'inhibiteurs a2a/a2b
|
WO2019166951A1
(en)
|
2018-02-28 |
2019-09-06 |
Novartis Ag |
Indole-2-carbonyl compounds and their use for the treatment of hepatitis b
|
WO2019169229A1
(en)
|
2018-03-01 |
2019-09-06 |
Nextcure, Inc. |
Klrg1 binding compositions and methods of use thereof
|
TWI708787B
(zh)
|
2018-03-02 |
2020-11-01 |
美商美國禮來大藥廠 |
Pd-1促效劑抗體及其用途
|
WO2019170727A1
(en)
|
2018-03-06 |
2019-09-12 |
Institut Curie |
Inhibitor of setdb1 histone methyltransferase for use in cancer combination therapy
|
US20210030703A1
(en)
|
2018-03-12 |
2021-02-04 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of caloric restriction mimetics for potentiating chemo-immunotherapy for the treatment of cancers
|
US20210238280A1
(en)
|
2018-03-14 |
2021-08-05 |
Elstar Therapeutics, Inc. |
Multifunctional molecules that bind to calreticulin and uses thereof
|
EP3765516A2
(en)
|
2018-03-14 |
2021-01-20 |
Elstar Therapeutics, Inc. |
Multifunctional molecules and uses thereof
|
TW202003565A
(zh)
|
2018-03-23 |
2020-01-16 |
美商必治妥美雅史谷比公司 |
抗mica及/或micb抗體及其用途
|
CN108530537B
(zh)
*
|
2018-03-29 |
2019-07-02 |
中国人民解放军军事科学院军事医学研究院 |
Pd-1/pd-l1信号通路抑制剂
|
WO2019185792A1
(en)
|
2018-03-29 |
2019-10-03 |
Philogen S.P.A |
Cancer treatment using immunoconjugates and immune check-point inhibitors
|
WO2019191676A1
(en)
|
2018-03-30 |
2019-10-03 |
Bristol-Myers Squibb Company |
Methods of treating tumor
|
US11702430B2
(en)
|
2018-04-03 |
2023-07-18 |
Merck Sharp & Dohme Llc |
Aza-benzothiophene compounds as STING agonists
|
BR112020020085A8
(pt)
|
2018-04-03 |
2023-04-11 |
Merck Sharp & Dohme |
Composto, composição farmacêutica, e, métodos para induzir uma resposta imune, para induzir produção de interferons de tipo i dependentes de sting e para tratar um distúrbio de proliferação celular
|
CN112292399A
(zh)
|
2018-04-04 |
2021-01-29 |
百时美施贵宝公司 |
抗cd27抗体及其用途
|
WO2019193540A1
(en)
|
2018-04-06 |
2019-10-10 |
Glaxosmithkline Intellectual Property Development Limited |
Heteroaryl derivatives of formula (i) as atf4 inhibitors
|
WO2019193541A1
(en)
|
2018-04-06 |
2019-10-10 |
Glaxosmithkline Intellectual Property Development Limited |
Bicyclic aromatic ring derivatives of formula (i) as atf4 inhibitors
|
KR20200142542A
(ko)
|
2018-04-12 |
2020-12-22 |
브리스톨-마이어스 스큅 컴퍼니 |
Cd73 길항제 항체 및 pd-1/pd-l1 축 길항제 항체에 의한 항암 조합 요법
|
US20210147547A1
(en)
|
2018-04-13 |
2021-05-20 |
Novartis Ag |
Dosage Regimens For Anti-Pd-L1 Antibodies And Uses Thereof
|
BR112020021042A2
(pt)
|
2018-04-17 |
2021-01-19 |
Tempest Therapeutics, Inc. |
Carboxamidas bicíclicas e métodos de uso das mesmas
|
WO2019204665A1
(en)
|
2018-04-18 |
2019-10-24 |
Xencor, Inc. |
Pd-1 targeted heterodimeric fusion proteins containing il-15/il-15ra fc-fusion proteins and pd-1 antigen binding domains and uses thereof
|
CN112105645A
(zh)
|
2018-04-18 |
2020-12-18 |
Xencor股份有限公司 |
Il-15/il-15ra异二聚体fc融合蛋白及其用途
|
EP3781687A4
(en)
|
2018-04-20 |
2022-02-09 |
Merck Sharp & Dohme Corp. |
NEW RIG-I SUBSTITUTED AGONISTS: COMPOSITIONS AND METHODS THEREOF
|
WO2019207030A1
(en)
|
2018-04-26 |
2019-10-31 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting a response with an immune checkpoint inhibitor in a patient suffering from a lung cancer
|
MA52363A
(fr)
|
2018-04-26 |
2021-03-03 |
Agenus Inc |
Compositions peptidiques de liaison à une protéine de choc thermique (hsp) et leurs méthodes d'utilisation
|
WO2019210153A1
(en)
|
2018-04-27 |
2019-10-31 |
Novartis Ag |
Car t cell therapies with enhanced efficacy
|
US20210396739A1
(en)
|
2018-05-01 |
2021-12-23 |
Novartis Ag |
Biomarkers for evaluating car-t cells to predict clinical outcome
|
AU2019262579A1
(en)
|
2018-05-04 |
2020-12-24 |
Incyte Corporation |
Salts of an FGFR inhibitor
|
AU2019262195A1
(en)
|
2018-05-04 |
2020-12-24 |
Incyte Corporation |
Solid forms of an FGFR inhibitor and processes for preparing the same
|
US20210363216A1
(en)
|
2018-05-14 |
2021-11-25 |
Immunocore Limited |
Bifunctional binding polypeptides
|
GB201807924D0
(en)
|
2018-05-16 |
2018-06-27 |
Ctxt Pty Ltd |
Compounds
|
MA52940A
(fr)
|
2018-05-18 |
2021-04-28 |
Incyte Corp |
Dérivés de pyrimidine fusionnés utilisés en tant qu'inhibiteurs de a2a/a2b
|
WO2019222706A1
(en)
|
2018-05-18 |
2019-11-21 |
Twist Bioscience Corporation |
Polynucleotides, reagents, and methods for nucleic acid hybridization
|
US10969381B2
(en)
|
2018-05-23 |
2021-04-06 |
Celgene Corporation |
Methods for treating multiple myeloma and the use of companion biomarkers for 4-(4-(4-(((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)oxy)methyl)benzyl)piperazin-1-yl)-3-fluorobenzonitrile
|
AU2019274530A1
(en)
|
2018-05-23 |
2020-12-10 |
Celgene Corporation |
Antiproliferative compounds and bispecific antibody against BCMA and CD3 for combined use
|
AR126019A1
(es)
|
2018-05-30 |
2023-09-06 |
Novartis Ag |
Anticuerpos frente a entpd2, terapias de combinación y métodos de uso de los anticuerpos y las terapias de combinación
|
EP3810116B1
(en)
|
2018-05-31 |
2023-11-15 |
Merck Sharp & Dohme LLC |
Novel substituted [1.1.1] bicyclo compounds as indoleamine 2,3-dioxygenase inhibitors
|
EP3810109A4
(en)
|
2018-05-31 |
2022-03-16 |
Peloton Therapeutics, Inc. |
COMPOSITIONS AND METHODS FOR INHIBITING CD73
|
WO2019229699A1
(en)
|
2018-05-31 |
2019-12-05 |
Novartis Ag |
Hepatitis b antibodies
|
US20210214459A1
(en)
|
2018-05-31 |
2021-07-15 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
CN112512578A
(zh)
|
2018-06-01 |
2021-03-16 |
诺华股份有限公司 |
结合cd123和cd3的双特异性抗体的给药
|
EP3802611A2
(en)
|
2018-06-01 |
2021-04-14 |
Novartis AG |
Binding molecules against bcma and uses thereof
|
WO2019234576A1
(en)
|
2018-06-03 |
2019-12-12 |
Lamkap Bio Beta Ltd. |
Bispecific antibodies against ceacam5 and cd47
|
SG11202011830SA
(en)
|
2018-06-13 |
2020-12-30 |
Novartis Ag |
Bcma chimeric antigen receptors and uses thereof
|
EP3806848A2
(en)
|
2018-06-15 |
2021-04-21 |
Flagship Pioneering Innovations V, Inc. |
Increasing immune activity through modulation of postcellular signaling factors
|
CN112533629A
(zh)
|
2018-06-19 |
2021-03-19 |
阿尔莫生物科技股份有限公司 |
结合使用il-10药剂与嵌合抗原受体细胞疗法的组合物和方法
|
MX2020014158A
(es)
|
2018-06-20 |
2021-04-12 |
Incyte Corp |
Anticuerpos anti proteína de muerte programada 1 (pd-1) y usos de estos.
|
TW202005985A
(zh)
|
2018-06-21 |
2020-02-01 |
美商再生元醫藥公司 |
用雙特異性抗CD3xMUC16抗體及抗PD-1抗體治療癌症的方法
|
WO2020005068A2
(en)
|
2018-06-29 |
2020-01-02 |
Stichting Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis |
Gene signatures and method for predicting response to pd-1 antagonists and ctla-4 antagonists, and combination thereof
|
WO2020010250A2
(en)
|
2018-07-03 |
2020-01-09 |
Elstar Therapeutics, Inc. |
Anti-tcr antibody molecules and uses thereof
|
CN112673093A
(zh)
*
|
2018-07-04 |
2021-04-16 |
赛通免疫治疗公司 |
靶向flt3、pd-1和/或pd-l1的免疫疗法的组合物和方法
|
CA3105942A1
(en)
|
2018-07-09 |
2020-01-16 |
Glaxosmithkline Intellectual Property Development Limited |
Chemical compounds
|
WO2020012334A1
(en)
|
2018-07-10 |
2020-01-16 |
Novartis Ag |
3-(5-hydroxy-1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and their use in the treatment of ikaros family zinc finger 2 (ikzf2)-dependent diseases
|
AR116109A1
(es)
|
2018-07-10 |
2021-03-31 |
Novartis Ag |
Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos
|
GB201811408D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Beta Ltd |
CD137 Binding Molecules
|
WO2020014583A1
(en)
|
2018-07-13 |
2020-01-16 |
Bristol-Myers Squibb Company |
Ox-40 agonist, pd-1 pathway inhibitor and ctla-4 inhibitor combination for use in a mehtod of treating a cancer or a solid tumor
|
EP3827020A1
(en)
|
2018-07-24 |
2021-06-02 |
Amgen Inc. |
Combination of lilrb1/2 pathway inhibitors and pd-1 pathway inhibitors
|
WO2020021465A1
(en)
|
2018-07-25 |
2020-01-30 |
Advanced Accelerator Applications (Italy) S.R.L. |
Method of treatment of neuroendocrine tumors
|
JP2021532143A
(ja)
|
2018-07-26 |
2021-11-25 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
癌の処置のためのlag−3併用療法
|
WO2020021061A1
(en)
|
2018-07-26 |
2020-01-30 |
Pieris Pharmaceuticals Gmbh |
Humanized anti-pd-1 antibodies and uses thereof
|
CN112703011A
(zh)
|
2018-08-06 |
2021-04-23 |
国家医疗保健研究所 |
用于治疗癌症的方法和组合物
|
WO2020030571A1
(en)
|
2018-08-06 |
2020-02-13 |
Glaxosmithkline Intellectual Property Development Limited |
Combinations of a pd-1 antibody and a tlr4 modulator and uses thereof
|
WO2020031107A1
(en)
|
2018-08-08 |
2020-02-13 |
Glaxosmithkline Intellectual Property Development Limited |
Chemical compounds
|
WO2020033791A1
(en)
|
2018-08-09 |
2020-02-13 |
Verseau Therapeutics, Inc. |
Oligonucleotide compositions for targeting ccr2 and csf1r and uses thereof
|
EP3843849A1
(en)
|
2018-08-27 |
2021-07-07 |
Pieris Pharmaceuticals GmbH |
Combination therapies comprising cd137/her2 bispecific agents and pd-1 axis inhibitors and uses thereof
|
WO2020044206A1
(en)
|
2018-08-29 |
2020-03-05 |
Glaxosmithkline Intellectual Property Development Limited |
Heterocyclic amides as kinase inhibitors for use in the treatment cancer
|
US11518792B2
(en)
|
2018-08-30 |
2022-12-06 |
HCW Biologics, Inc. |
Multi-chain chimeric polypeptides and uses thereof
|
EP3843788A1
(en)
|
2018-08-30 |
2021-07-07 |
HCW Biologics, Inc. |
Single-chain chimeric polypeptides and uses thereof
|
JP2021534835A
(ja)
|
2018-08-30 |
2021-12-16 |
エイチシーダブリュー バイオロジックス インコーポレイテッド |
一本鎖および多鎖キメラポリペプチドならびにその使用方法
|
WO2020047345A1
(en)
|
2018-08-31 |
2020-03-05 |
Yale University |
Compositions and methods of using cell-penetrating antibodies in combination with immune checkpoint modulators
|
WO2020044252A1
(en)
|
2018-08-31 |
2020-03-05 |
Novartis Ag |
Dosage regimes for anti-m-csf antibodies and uses thereof
|
WO2020048942A1
(en)
|
2018-09-04 |
2020-03-12 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for enhancing cytotoxic t lymphocyte-dependent immune responses
|
WO2020049534A1
(en)
|
2018-09-07 |
2020-03-12 |
Novartis Ag |
Sting agonist and combination therapy thereof for the treatment of cancer
|
JP2022508015A
(ja)
|
2018-09-07 |
2022-01-19 |
ファイザー・インク |
抗αvβ8抗体、組成物及びその使用
|
WO2020053742A2
(en)
|
2018-09-10 |
2020-03-19 |
Novartis Ag |
Anti-hla-hbv peptide antibodies
|
EP3849979A1
(en)
|
2018-09-12 |
2021-07-21 |
Novartis AG |
Antiviral pyridopyrazinedione compounds
|
US20220177587A1
(en)
|
2018-09-19 |
2022-06-09 |
Alpine Immune Sciences, Inc. |
Methods and uses of variant cd80 fusion proteins and related constructs
|
JP2022511337A
(ja)
|
2018-09-19 |
2022-01-31 |
インサーム (インスティテュート ナショナル デ ラ サンテ エ デ ラ ルシェルシェ メディカル) |
免疫チェックポイント治療に抵抗性のある癌の治療のための方法および医薬組成物
|
SG11202103022WA
(en)
|
2018-09-25 |
2021-04-29 |
Harpoon Therapeutics Inc |
Dll3 binding proteins and methods of use
|
CN113164777A
(zh)
|
2018-09-27 |
2021-07-23 |
马伦戈治疗公司 |
Csf1r/ccr2多特异性抗体
|
EP3856779A1
(en)
|
2018-09-28 |
2021-08-04 |
Novartis AG |
Cd22 chimeric antigen receptor (car) therapies
|
US20210347851A1
(en)
|
2018-09-28 |
2021-11-11 |
Novartis Ag |
Cd19 chimeric antigen receptor (car) and cd22 car combination therapies
|
KR20210068473A
(ko)
|
2018-09-29 |
2021-06-09 |
노파르티스 아게 |
Shp2 활성 억제용 화합물의 제조 방법
|
US20220040183A1
(en)
|
2018-10-01 |
2022-02-10 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of inhibitors of stress granule formation for targeting the regulation of immune responses
|
WO2020072821A2
(en)
|
2018-10-03 |
2020-04-09 |
Xencor, Inc. |
Il-12 heterodimeric fc-fusion proteins
|
EP3864046A1
(en)
|
2018-10-09 |
2021-08-18 |
Bristol-Myers Squibb Company |
Anti-mertk antibodies for treating cancer
|
US11066404B2
(en)
|
2018-10-11 |
2021-07-20 |
Incyte Corporation |
Dihydropyrido[2,3-d]pyrimidinone compounds as CDK2 inhibitors
|
MA53862A
(fr)
|
2018-10-12 |
2022-01-19 |
Xencor Inc |
Protéines de fusion fc d'il-15/il-15ralpha ciblant pd-1 et utilisations dans des polythérapies faisant intervenir celles-ci
|
JP2022504905A
(ja)
|
2018-10-16 |
2022-01-13 |
ノバルティス アーゲー |
標的化療法に対する応答を予測するためのバイオマーカーとしての単独の又は免疫マーカーと組み合わせた腫瘍突然変異負荷
|
CA3115802A1
(en)
|
2018-10-17 |
2020-04-23 |
Biolinerx Ltd. |
Treatment of metastatic pancreatic adenocarcinoma
|
EP3867269A1
(en)
|
2018-10-18 |
2021-08-25 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Combination of a big-h3 antagonist and an immune checkpoint inhibitor for the treatment of solid tumor
|
CA3117016A1
(en)
|
2018-10-19 |
2020-04-23 |
Bristol-Myers Squibb Company |
Combination therapy for melanoma
|
JP2022505524A
(ja)
|
2018-10-22 |
2022-01-14 |
グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッド |
投薬
|
KR20210081384A
(ko)
|
2018-10-23 |
2021-07-01 |
브리스톨-마이어스 스큅 컴퍼니 |
종양을 치료하는 방법
|
CA3117050A1
(en)
|
2018-10-29 |
2020-05-07 |
Mersana Therapeutics, Inc. |
Cysteine engineered antibody-drug conjugates with peptide-containing linkers
|
EP3873532A1
(en)
|
2018-10-31 |
2021-09-08 |
Novartis AG |
Dc-sign antibody drug conjugates
|
JP2022506598A
(ja)
|
2018-11-01 |
2022-01-17 |
ジュノー セラピューティクス インコーポレイテッド |
Gタンパク質共役受容体クラスcグループ5メンバーd(gprc5d)に特異的なキメラ抗原受容体
|
CN113646335A
(zh)
|
2018-11-01 |
2021-11-12 |
朱诺治疗学股份有限公司 |
使用对b细胞成熟抗原具有特异性的嵌合抗原受体的治疗的方法
|
EP3873464A4
(en)
|
2018-11-01 |
2022-06-08 |
Merck Sharp & Dohme Corp. |
NOVEL SUBSTITUTED PYRAZOLE COMPOUNDS AS INDOLAMINE-2,3-DIOXYGENASE INHIBITORS
|
WO2020096871A1
(en)
|
2018-11-06 |
2020-05-14 |
Merck Sharp & Dohme Corp. |
Novel substituted tricyclic compounds as indoleamine 2,3-dioxygenase inhibitors
|
WO2020102375A1
(en)
|
2018-11-14 |
2020-05-22 |
Regeneron Pharmaceuticals, Inc. |
Intralesional administration of pd-1 inhibitors for treating skin cancer
|
TW202028222A
(zh)
|
2018-11-14 |
2020-08-01 |
美商Ionis製藥公司 |
Foxp3表現之調節劑
|
US20220008515A1
(en)
|
2018-11-16 |
2022-01-13 |
Neoimmunetech, Inc. |
Method of treating a tumor with a combination of il-7 protein and an immune checkpoint inhibitor
|
AU2019381827A1
(en)
|
2018-11-16 |
2021-06-10 |
Juno Therapeutics, Inc. |
Methods of dosing engineered T cells for the treatment of B cell malignancies
|
PE20211284A1
(es)
|
2018-11-16 |
2021-07-19 |
Bristol Myers Squibb Co |
Anticuerpos anti-nkg2a y usos de los mismos
|
KR20210093946A
(ko)
|
2018-11-16 |
2021-07-28 |
아르퀼 인코포레이티드 |
암의 치료를 위한 제약 조합물
|
WO2020104496A1
(en)
|
2018-11-20 |
2020-05-28 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Bispecific antibody targeting transferrin receptor 1 and soluble antigen
|
US20220040184A1
(en)
|
2018-11-20 |
2022-02-10 |
Merck Sharp Dohme Corp. |
Substituted amino triazolopyrimidine and amino triazolopyrazine adenosine receptor antagonists, pharmaceutical compositions and their use
|
CA3119774A1
(en)
|
2018-11-20 |
2020-05-28 |
Merck Sharp & Dohme Corp. |
Substituted amino triazolopyrimidine and amino triazolopyrazine adenosine receptor antagonists, pharmaceutical compositions and their use
|
WO2020104479A1
(en)
|
2018-11-20 |
2020-05-28 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating cancers and resistant cancers with anti transferrin receptor 1 antibodies
|
CN113453678A
(zh)
|
2018-11-26 |
2021-09-28 |
德彪药业国际股份公司 |
Hiv感染的联合治疗
|
WO2020112581A1
(en)
|
2018-11-28 |
2020-06-04 |
Merck Sharp & Dohme Corp. |
Novel substituted piperazine amide compounds as indoleamine 2, 3-dioxygenase (ido) inhibitors
|
US20220018828A1
(en)
|
2018-11-28 |
2022-01-20 |
Inserm (Institut National De La Santé Et La Recherche Médicale |
Methods and kit for assaying lytic potential of immune effector cells
|
CR20210271A
(es)
|
2018-11-30 |
2021-07-14 |
Merck Sharp & Dohme |
Derivados de amino triazolo quinazolina 9-sustituidos como antagonistas del receptor de adenosina, composiciones farmacéuticas y su uso
|
SG11202105502RA
(en)
|
2018-11-30 |
2021-06-29 |
Juno Therapeutics Inc |
Methods for treatment using adoptive cell therapy
|
AU2019390729B2
(en)
|
2018-11-30 |
2022-08-11 |
Glaxosmithkline Intellectual Property Development Limited |
Compounds useful in HIV therapy
|
AU2019391097A1
(en)
|
2018-12-04 |
2021-05-20 |
Sumitomo Pharma Oncology, Inc. |
CDK9 inhibitors and polymorphs thereof for use as agents for treatment of cancer
|
US20220018835A1
(en)
|
2018-12-07 |
2022-01-20 |
INSERM (Institut National de la Santé et de la Recherche Médicale |
Use of cd26 and cd39 as new phenotypic markers for assessing maturation of foxp3+ t cells and uses thereof for diagnostic purposes
|
WO2020115261A1
(en)
|
2018-12-07 |
2020-06-11 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma
|
US10952996B2
(en)
|
2018-12-11 |
2021-03-23 |
Theravance Biopharma R&D Ip, Llc |
ALK5 inhibitors
|
WO2020120592A1
(en)
|
2018-12-12 |
2020-06-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for predicting and treating melanoma
|
EP3897624A1
(en)
|
2018-12-17 |
2021-10-27 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Use of sulconazole as a furin inhibitor
|
GB201820547D0
(en)
|
2018-12-17 |
2019-01-30 |
Oxford Univ Innovation |
Modified antibodies
|
WO2020127411A1
(en)
|
2018-12-19 |
2020-06-25 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating cancers by immuno-modulation using antibodies against cathespin-d
|
EP3897637A1
(en)
|
2018-12-20 |
2021-10-27 |
Novartis AG |
Dosing regimen and pharmaceutical combination comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives
|
WO2020132646A1
(en)
|
2018-12-20 |
2020-06-25 |
Xencor, Inc. |
Targeted heterodimeric fc fusion proteins containing il-15/il-15ra and nkg2d antigen binding domains
|
JP2022514087A
(ja)
|
2018-12-21 |
2022-02-09 |
ノバルティス アーゲー |
IL-1β結合抗体の使用
|
WO2020127885A1
(en)
|
2018-12-21 |
2020-06-25 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Compositions for treating cancers and resistant cancers
|
WO2020128637A1
(en)
|
2018-12-21 |
2020-06-25 |
Novartis Ag |
Use of il-1 binding antibodies in the treatment of a msi-h cancer
|
AU2019403445A1
(en)
|
2018-12-21 |
2021-07-29 |
Aim Immunotech Inc. |
Compositions and methods for cancer therapy
|
BR112021011900A2
(pt)
|
2018-12-21 |
2021-09-08 |
Novartis Ag |
Anticorpos para pmel17 e conjugados dos mesmos
|
WO2020127965A1
(en)
|
2018-12-21 |
2020-06-25 |
Onxeo |
New conjugated nucleic acid molecules and their uses
|
US20220025036A1
(en)
|
2018-12-21 |
2022-01-27 |
Novartis Ag |
Use of il-1beta binding antibodies
|
SG11202104699TA
(en)
|
2018-12-21 |
2021-07-29 |
Novartis Ag |
Use of il-1 beta antibodies in the treatment or prevention of myelodysplastic syndrome
|
EP3902529A1
(en)
|
2018-12-27 |
2021-11-03 |
Amgen Inc. |
Lyophilized virus formulations
|
CA3125476A1
(en)
|
2019-01-03 |
2020-07-09 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Methods and pharmaceutical compositions for enhancing cd8+ t cell-dependent immune responses in subjects suffering from cancer
|
EP3908254A1
(en)
|
2019-01-09 |
2021-11-17 |
Celgene Corporation |
Pharmaceutical compositions comprising (s)-4-(4-(4-(((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)oxy)methyl) benzyl)piperazin-1-yl)-3-fluorobenzonitrile and methods of using the same
|
MX2021008294A
(es)
|
2019-01-09 |
2021-10-13 |
Celgene Corp |
Compuestos antiproliferativos y segundos agentes activos para uso en el tratamiento del mieloma múltiple.
|
JP2022518175A
(ja)
|
2019-01-09 |
2022-03-14 |
セルジーン コーポレイション |
(s)-4-(4-(4-(((2-(2,6-ジオキソピペリジン-3-イル)-1-オキソイソインドリン-4-イル)オキシ)メチル)ベンジル)ピペラジン-1-イル)-3-フルオロベンゾニトリルを含む固体形態及びその塩、ならびにそれらを含む組成物及びその使用方法
|
SG11202107606VA
(en)
|
2019-01-15 |
2021-08-30 |
Inst Nat Sante Rech Med |
Mutated interleukin-34 (il-34) polypeptides and uses thereof in therapy
|
CN113645960A
(zh)
|
2019-01-17 |
2021-11-12 |
佐治亚技术研究公司 |
含有氧化的胆固醇的药物递送系统
|
KR20210122272A
(ko)
|
2019-01-29 |
2021-10-08 |
주노 쎄러퓨티크스 인코퍼레이티드 |
수용체 티로신 키나제 유사 고아 수용체 1(ror1)에 특이적인 항체 및 키메라 항원 수용체
|
TWI829857B
(zh)
|
2019-01-29 |
2024-01-21 |
美商英塞特公司 |
作為a2a / a2b抑制劑之吡唑并吡啶及三唑并吡啶
|
WO2020157131A1
(en)
|
2019-01-30 |
2020-08-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for identifying whether a subject suffering from a cancer will achieve a response with an immune-checkpoint inhibitor
|
US20220117911A1
(en)
|
2019-02-04 |
2022-04-21 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for modulating blood-brain barrier
|
CN113412262A
(zh)
|
2019-02-12 |
2021-09-17 |
大日本住友制药肿瘤公司 |
包含杂环蛋白激酶抑制剂的制剂
|
JP2022519385A
(ja)
|
2019-02-12 |
2022-03-23 |
ノバルティス アーゲー |
Tno155及びpd-1阻害剤を含む医薬組合せ
|
WO2020165370A1
(en)
|
2019-02-13 |
2020-08-20 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for selecting a cancer treatment in a subject suffering from cancer
|
EP3924521A4
(en)
|
2019-02-15 |
2023-03-29 |
IncellDx, Inc. |
BLADDER-ASSOCIATED SPECIMEN ASSAY, IDENTIFICATION AND TREATMENT OF BLADDER-ASSOCIATED NEOPLASIA, AND KITS FOR USE THEREOF
|
WO2020165833A1
(en)
|
2019-02-15 |
2020-08-20 |
Novartis Ag |
3-(1-oxo-5-(piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
US11384083B2
(en)
|
2019-02-15 |
2022-07-12 |
Incyte Corporation |
Substituted spiro[cyclopropane-1,5′-pyrrolo[2,3-d]pyrimidin]-6′(7′h)-ones as CDK2 inhibitors
|
CA3123519A1
(en)
|
2019-02-15 |
2020-08-20 |
Novartis Ag |
Substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
TW202045181A
(zh)
|
2019-02-15 |
2020-12-16 |
美商英塞特公司 |
細胞週期蛋白依賴性激酶2生物標記物及其用途
|
WO2020169472A2
(en)
|
2019-02-18 |
2020-08-27 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods of inducing phenotypic changes in macrophages
|
WO2020172553A1
(en)
|
2019-02-22 |
2020-08-27 |
Novartis Ag |
Combination therapies of egfrviii chimeric antigen receptors and pd-1 inhibitors
|
WO2020176680A1
(en)
*
|
2019-02-26 |
2020-09-03 |
Twist Bioscience Corporation |
Variant nucleic acid libraries for antibody optimization
|
WO2020176699A1
(en)
|
2019-02-28 |
2020-09-03 |
Regeneron Pharmaceuticals, Inc. |
Administration of pd-1 inhibitors for treating skin cancer
|
WO2020180959A1
(en)
|
2019-03-05 |
2020-09-10 |
Incyte Corporation |
Pyrazolyl pyrimidinylamine compounds as cdk2 inhibitors
|
CA3131529A1
(en)
|
2019-03-05 |
2020-09-10 |
Amgen Inc. |
Use of oncolytic viruses for the treatment of cancer
|
JP2022523804A
(ja)
|
2019-03-06 |
2022-04-26 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
がんの処置における増強された有効性のためのil-4/il-13経路阻害剤
|
US11628162B2
(en)
|
2019-03-08 |
2023-04-18 |
Incyte Corporation |
Methods of treating cancer with an FGFR inhibitor
|
WO2020183011A1
(en)
|
2019-03-14 |
2020-09-17 |
Institut Curie |
Htr1d inhibitors and uses thereof in the treatment of cancer
|
WO2020187998A1
(en)
|
2019-03-19 |
2020-09-24 |
Fundació Privada Institut D'investigació Oncològica De Vall Hebron |
Combination therapy with omomyc and an antibody binding pd-1 or ctla-4 for the treatment of cancer
|
JP2022525149A
(ja)
|
2019-03-20 |
2022-05-11 |
スミトモ ダイニッポン ファーマ オンコロジー, インコーポレイテッド |
ベネトクラクスが失敗した急性骨髄性白血病(aml)の処置
|
JP2022519923A
(ja)
|
2019-03-22 |
2022-03-25 |
スミトモ ダイニッポン ファーマ オンコロジー, インコーポレイテッド |
Pkm2モジュレーターを含む組成物およびそれを使用する処置の方法
|
EP3946628A1
(en)
|
2019-03-28 |
2022-02-09 |
Bristol-Myers Squibb Company |
Methods of treating tumor
|
JP2022527177A
(ja)
|
2019-03-28 |
2022-05-31 |
ブリストル-マイヤーズ スクイブ カンパニー |
腫瘍を処置する方法
|
WO2020201095A1
(en)
|
2019-03-29 |
2020-10-08 |
Institut Curie |
Interleukin-2 variants with modified biological activity
|
TW202102543A
(zh)
|
2019-03-29 |
2021-01-16 |
美商安進公司 |
溶瘤病毒在癌症新輔助療法中之用途
|
WO2020205560A1
(en)
|
2019-03-29 |
2020-10-08 |
Incyte Corporation |
Sulfonylamide compounds as cdk2 inhibitors
|
US20220177978A1
(en)
|
2019-04-02 |
2022-06-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods of predicting and preventing cancer in patients having premalignant lesions
|
EP3946324A4
(en)
|
2019-04-04 |
2022-11-30 |
Merck Sharp & Dohme LLC |
HISTONE DEACETYLASE-3 INHIBITORS USEFUL FOR THE TREATMENT OF CANCER, INFLAMMATION, NEURODEGENERATIVE DISEASES AND DIABETES
|
US20220160692A1
(en)
|
2019-04-09 |
2022-05-26 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of sk2 inhibitors in combination with immune checkpoint blockade therapy for the treatment of cancer
|
US20220220480A1
(en)
|
2019-04-17 |
2022-07-14 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treatment of nlrp3 inflammasome mediated il-1beta dependent disorders
|
WO2020221796A1
(en)
|
2019-04-30 |
2020-11-05 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma
|
WO2020223558A1
(en)
|
2019-05-01 |
2020-11-05 |
Incyte Corporation |
Tricyclic amine compounds as cdk2 inhibitors
|
US11440914B2
(en)
|
2019-05-01 |
2022-09-13 |
Incyte Corporation |
Tricyclic amine compounds as CDK2 inhibitors
|
EP3962493A2
(en)
|
2019-05-03 |
2022-03-09 |
Flagship Pioneering Innovations V, Inc. |
Methods of modulating immune activity/level of irf or sting or of treating cancer, comprising the administration of a sting modulator and/or purinergic receptor modulator or postcellular signaling factor
|
EP3965821A1
(en)
|
2019-05-07 |
2022-03-16 |
Immunicom, Inc. |
Increasing responses to checkpoint inhibitors by extracorporeal apheresis
|
JP2022532490A
(ja)
|
2019-05-13 |
2022-07-15 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
癌の治療における有効性の増強のためのpd-1阻害剤とlag-3阻害剤の組み合わせ
|
JP2022533390A
(ja)
|
2019-05-16 |
2022-07-22 |
スティングセラ インコーポレイテッド |
オキソアクリジニル酢酸誘導体および使用方法
|
US20220251079A1
(en)
|
2019-05-16 |
2022-08-11 |
Stingthera, Inc. |
Benzo[b][1,8]naphthyridine acetic acid derivatives and methods of use
|
BR112021023345A2
(pt)
|
2019-05-20 |
2022-02-01 |
Pandion Operations Inc |
Imunotolerância com alvo em madcam
|
EP3976090A1
(en)
|
2019-05-24 |
2022-04-06 |
Pfizer Inc. |
Combination therapies using cdk inhibitors
|
KR20220016155A
(ko)
|
2019-05-30 |
2022-02-08 |
브리스톨-마이어스 스큅 컴퍼니 |
면역-종양학 (i-o) 요법에 적합한 대상체를 확인하는 방법
|
EP3976831A1
(en)
|
2019-05-30 |
2022-04-06 |
Bristol-Myers Squibb Company |
Multi-tumor gene signatures for suitability to immuno-oncology therapy
|
KR20220016157A
(ko)
|
2019-05-30 |
2022-02-08 |
브리스톨-마이어스 스큅 컴퍼니 |
세포 국재화 시그너쳐 및 조합 요법
|
BR112021024507A2
(pt)
*
|
2019-06-05 |
2022-03-08 |
Anaptysbio Inc |
Agonista de pd-1 e método de uso do mesmo
|
US11246906B2
(en)
|
2019-06-11 |
2022-02-15 |
Alkermes Pharma Ireland Limited |
Compositions and methods for subcutaneous administration of cancer immunotherapy
|
CN113924117A
(zh)
|
2019-06-14 |
2022-01-11 |
蒂尔坦生物制药有限公司 |
溶瘤腺病毒和检查点抑制剂联合疗法
|
EP3986460A2
(en)
|
2019-06-18 |
2022-04-27 |
Janssen Sciences Ireland Unlimited Company |
Combination of hepatitis b virus (hbv) vaccines and anti-pd-1 antibody
|
CN114630675A
(zh)
|
2019-06-18 |
2022-06-14 |
爱尔兰詹森科学公司 |
乙型肝炎病毒(hbv)疫苗和抗pd-1或抗pd-l1抗体的组合
|
CN114729342A
(zh)
|
2019-06-21 |
2022-07-08 |
特韦斯特生物科学公司 |
基于条形码的核酸序列装配
|
WO2020257639A1
(en)
|
2019-06-21 |
2020-12-24 |
HCW Biologics, Inc. |
Multi-chain chimeric polypeptides and uses thereof
|
EP3990635A1
(en)
|
2019-06-27 |
2022-05-04 |
Rigontec GmbH |
Design method for optimized rig-i ligands
|
CA3138188A1
(en)
|
2019-07-02 |
2021-01-07 |
Fred Hutchinson Cancer Research Center |
Recombinant ad35 vectors and related gene therapy improvements
|
CN114302878A
(zh)
|
2019-07-03 |
2022-04-08 |
大日本住友制药肿瘤公司 |
酪氨酸激酶非受体1(tnk1)抑制剂及其用途
|
JP6881658B2
(ja)
|
2019-07-05 |
2021-06-02 |
小野薬品工業株式会社 |
Pd−1/cd3二重特異性タンパク質による血液がん治療
|
US11591329B2
(en)
|
2019-07-09 |
2023-02-28 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
CN110384657A
(zh)
*
|
2019-07-15 |
2019-10-29 |
三峡大学 |
靶向PD-L1载miR-34a微泡的制备方法及在制备抑制宫颈癌的药物上的应用
|
GB201910304D0
(en)
|
2019-07-18 |
2019-09-04 |
Ctxt Pty Ltd |
Compounds
|
GB201910305D0
(en)
|
2019-07-18 |
2019-09-04 |
Ctxt Pty Ltd |
Compounds
|
US11083705B2
(en)
|
2019-07-26 |
2021-08-10 |
Eisai R&D Management Co., Ltd. |
Pharmaceutical composition for treating tumor
|
WO2021023698A1
(en)
|
2019-08-02 |
2021-02-11 |
Lanthiopep B.V |
Angiotensin type 2 (at2) receptor agonists for use in the treatment of cancer
|
US11155567B2
(en)
|
2019-08-02 |
2021-10-26 |
Mersana Therapeutics, Inc. |
Sting agonist compounds and methods of use
|
WO2021024020A1
(en)
|
2019-08-06 |
2021-02-11 |
Astellas Pharma Inc. |
Combination therapy involving antibodies against claudin 18.2 and immune checkpoint inhibitors for treatment of cancer
|
WO2021025140A1
(ja)
|
2019-08-08 |
2021-02-11 |
小野薬品工業株式会社 |
二重特異性タンパク質
|
KR20220061977A
(ko)
|
2019-08-12 |
2022-05-13 |
퓨리노미아 바이오테크, 아이엔씨. |
Cd39 발현 세포의 adcc 표적화를 통해 t 세포 매개 면역 반응을 촉진 및 강화하기 위한 방법 및 조성물
|
CN116348458A
(zh)
|
2019-08-14 |
2023-06-27 |
因赛特公司 |
作为cdk2抑制剂的咪唑基嘧啶基胺化合物
|
GB201912107D0
(en)
|
2019-08-22 |
2019-10-09 |
Amazentis Sa |
Combination
|
WO2021042019A1
(en)
|
2019-08-30 |
2021-03-04 |
Agenus Inc. |
Anti-cd96 antibodies and methods of use thereof
|
WO2021048292A1
(en)
|
2019-09-11 |
2021-03-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma
|
CN114761386A
(zh)
|
2019-09-17 |
2022-07-15 |
比亚尔R&D投资股份公司 |
作为酸性神经酰胺酶抑制剂的经取代n-杂环甲酰胺及其作为药物的用途
|
US20220411388A1
(en)
|
2019-09-17 |
2022-12-29 |
Bial - R&D Investments, S.A. |
Substituted imidazole carboxamides and their use in the treatment of medical disorders
|
KR20220100860A
(ko)
|
2019-09-17 |
2022-07-18 |
비알 - 알&디 인베스트먼츠, 에스.에이. |
질병의 치료에 사용하기 위한 치환된, 포화 및 불포화 n-헤테로시클릭 카르복사미드 및 관련 화합물
|
EP4031578A1
(en)
|
2019-09-18 |
2022-07-27 |
Novartis AG |
Entpd2 antibodies, combination therapies, and methods of using the antibodies and combination therapies
|
TW202124446A
(zh)
|
2019-09-18 |
2021-07-01 |
瑞士商諾華公司 |
與entpd2抗體之組合療法
|
BR112022004995A2
(pt)
|
2019-09-18 |
2022-06-21 |
Lamkap Bio Alpha AG |
Anticorpos biespecíficos contra ceacam5 e cd3
|
BR112022004475A2
(pt)
|
2019-09-18 |
2022-05-31 |
Novartis Ag |
Proteínas de fusão nkg2d e usos das mesmas
|
KR20220066334A
(ko)
|
2019-09-22 |
2022-05-24 |
브리스톨-마이어스 스큅 컴퍼니 |
Lag-3 길항제 요법에 대한 정량적 공간 프로파일링
|
AU2020351751A1
(en)
|
2019-09-25 |
2022-04-21 |
Seagen Inc. |
Combination anti-CD30 ADC, anti-PD-1 and chemotherapeutic for treatment of hematopoietic cancers
|
AU2020353079A1
(en)
|
2019-09-25 |
2022-04-14 |
Bristol-Myers Squibb Company |
Composite biomarker for cancer therapy
|
CN114667285A
(zh)
|
2019-09-26 |
2022-06-24 |
诺华股份有限公司 |
抗病毒吡唑并吡啶酮化合物
|
MX2022003523A
(es)
|
2019-09-27 |
2022-04-25 |
Glaxosmithkline Ip Dev Ltd |
Proteinas de union a antigenos.
|
CA3151322A1
(en)
|
2019-10-01 |
2021-04-08 |
Silverback Therapeutics, Inc. |
Combination therapy with immune stimulatory conjugates
|
EP3800201A1
(en)
|
2019-10-01 |
2021-04-07 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Cd28h stimulation enhances nk cell killing activities
|
WO2021064180A1
(en)
|
2019-10-03 |
2021-04-08 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for modulating macrophages polarization
|
WO2021067863A2
(en)
|
2019-10-03 |
2021-04-08 |
Xencor, Inc. |
Targeted il-12 heterodimeric fc-fusion proteins
|
WO2021064184A1
(en)
|
2019-10-04 |
2021-04-08 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical composition for the treatment of ovarian cancer, breast cancer or pancreatic cancer
|
WO2021072232A1
(en)
|
2019-10-11 |
2021-04-15 |
Incyte Corporation |
Bicyclic amines as cdk2 inhibitors
|
TW202128757A
(zh)
|
2019-10-11 |
2021-08-01 |
美商建南德克公司 |
具有改善之特性的 PD-1 標靶 IL-15/IL-15Rα FC 融合蛋白
|
BR112022007163A2
(pt)
|
2019-10-14 |
2022-08-23 |
Incyte Corp |
Heterociclos bicíclicos como inibidores de fgfr
|
US11566028B2
(en)
|
2019-10-16 |
2023-01-31 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
CA3157889A1
(en)
|
2019-10-17 |
2021-04-22 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Methods for diagnosing nasal intestinal type adenocarcinomas
|
JP2022553293A
(ja)
|
2019-10-21 |
2022-12-22 |
ノバルティス アーゲー |
ベネトクラックスおよびtim-3阻害剤を用いた併用療法
|
CA3157665A1
(en)
|
2019-10-21 |
2021-04-29 |
Novartis Ag |
Tim-3 inhibitors and uses thereof
|
EP4048304A1
(en)
|
2019-10-22 |
2022-08-31 |
Institut Curie |
Immunotherapy targeting tumor neoantigenic peptides
|
NL2024108B1
(en)
|
2019-10-26 |
2021-07-19 |
Vitroscan B V |
Methods and apparatus for measuring immune-cell mediated anti-tumoroid responses
|
EP4053124A1
(en)
|
2019-10-28 |
2022-09-07 |
Shanghai Institute of Materia Medica, Chinese Academy of Sciences |
Five-membered heterocyclic oxocarboxylic acid compound and medical use thereof
|
WO2021083959A1
(en)
|
2019-10-29 |
2021-05-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating uveal melanoma
|
CN115023227A
(zh)
|
2019-10-29 |
2022-09-06 |
卫材R&D管理有限公司 |
用于治疗癌症的PD-1拮抗剂、VEGFR/FGFR/RET酪氨酸激酶抑制剂和CBP/β-联蛋白抑制剂的组合
|
US20220390455A1
(en)
|
2019-11-05 |
2022-12-08 |
Bristol-Myers Squibb Company |
M-protein assays and uses thereof
|
WO2021092220A1
(en)
|
2019-11-06 |
2021-05-14 |
Bristol-Myers Squibb Company |
Methods of identifying a subject with a tumor suitable for a checkpoint inhibitor therapy
|
WO2021092221A1
(en)
|
2019-11-06 |
2021-05-14 |
Bristol-Myers Squibb Company |
Methods of identifying a subject with a tumor suitable for a checkpoint inhibitor therapy
|
US20220411499A1
(en)
|
2019-11-08 |
2022-12-29 |
Bristol-Myers Squibb Company |
LAG-3 Antagonist Therapy for Melanoma
|
JP2023500395A
(ja)
|
2019-11-11 |
2023-01-05 |
インサイト・コーポレイション |
Pd-1/pd-l1阻害剤の塩及び結晶形態
|
US20220395553A1
(en)
|
2019-11-14 |
2022-12-15 |
Cohbar, Inc. |
Cxcr4 antagonist peptides
|
EP4061809A1
(en)
|
2019-11-22 |
2022-09-28 |
Theravance Biopharma R&D IP, LLC |
Substituted 1,5-naphthyridines or quinolines as alk5 inhibitors
|
EP3824954A1
(en)
|
2019-11-22 |
2021-05-26 |
Centre National de la Recherche Scientifique |
Device, apparatus and method for minibeam radiation therapy
|
JP2023502264A
(ja)
|
2019-11-22 |
2023-01-23 |
スミトモ ファーマ オンコロジー, インコーポレイテッド |
固体用量医薬組成物
|
US20210154281A1
(en)
|
2019-11-26 |
2021-05-27 |
Massachusetts Institute Of Technology |
Cell-based cancer vaccines and cancer therapies
|
CN114945382A
(zh)
|
2019-11-26 |
2022-08-26 |
诺华股份有限公司 |
Cd19和cd22嵌合抗原受体及其用途
|
EP3831849A1
(en)
|
2019-12-02 |
2021-06-09 |
LamKap Bio beta AG |
Bispecific antibodies against ceacam5 and cd47
|
ES2961245T3
(es)
|
2019-12-04 |
2024-03-11 |
Orna Therapeutics Inc |
Composiciones y métodos de ARN circular
|
KR20220131900A
(ko)
|
2019-12-04 |
2022-09-29 |
인사이트 코포레이션 |
Fgfr 억제제의 유도체
|
JP2023505258A
(ja)
|
2019-12-04 |
2023-02-08 |
インサイト・コーポレイション |
Fgfr阻害剤としての三環式複素環
|
US11897950B2
(en)
|
2019-12-06 |
2024-02-13 |
Augusta University Research Institute, Inc. |
Osteopontin monoclonal antibodies
|
EP4069683A1
(en)
|
2019-12-06 |
2022-10-12 |
Mersana Therapeutics, Inc. |
Dimeric compounds as sting agonists
|
JP2023506187A
(ja)
|
2019-12-09 |
2023-02-15 |
シージェン インコーポレイテッド |
Liv1-adcおよびpd-1アンタゴニストとの併用療法
|
US20230114107A1
(en)
|
2019-12-17 |
2023-04-13 |
Flagship Pioneering Innovations V, Inc. |
Combination anti-cancer therapies with inducers of iron-dependent cellular disassembly
|
WO2021123243A1
(en)
|
2019-12-19 |
2021-06-24 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and vaccine compositions to treat cancers
|
IL294085A
(en)
|
2019-12-19 |
2022-08-01 |
Bristol Myers Squibb Co |
Combinations of dgk inhibitors and checkpoint antagonists
|
JP2023507190A
(ja)
|
2019-12-20 |
2023-02-21 |
ノバルティス アーゲー |
増殖性疾患を治療するための抗TGFβ抗体及びチェックポイント阻害薬の使用
|
WO2021138407A2
(en)
|
2020-01-03 |
2021-07-08 |
Marengo Therapeutics, Inc. |
Multifunctional molecules that bind to cd33 and uses thereof
|
CA3166549A1
(en)
|
2020-01-03 |
2021-07-08 |
Incyte Corporation |
Combination therapy comprising a2a/a2b and pd-1/pd-l1 inhibitors
|
US20230076415A1
(en)
|
2020-01-17 |
2023-03-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma
|
IL293752A
(en)
|
2020-01-17 |
2022-08-01 |
Novartis Ag |
A combination containing a tim-3 inhibitor and a substance that causes hypomethylation for use in the treatment of myeloplastic syndrome or chronic myelomonocytic leukemia
|
CA3165460A1
(en)
|
2020-01-28 |
2021-08-05 |
Genentech, Inc. |
Il15/il15r alpha heterodimeric fc-fusion proteins for the treatment of cancer
|
IL295093A
(en)
|
2020-01-30 |
2022-09-01 |
Ona Therapeutics S L |
Combined treatment for cancer and cancer metastases
|
EP4100126A1
(en)
|
2020-02-05 |
2022-12-14 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Methods for discontinuing a treatment with a tyrosine kinase inhibitor (tki)
|
JP2023514152A
(ja)
|
2020-02-06 |
2023-04-05 |
ブリストル-マイヤーズ スクイブ カンパニー |
Il-10およびその使用
|
IL295083A
(en)
|
2020-02-11 |
2022-09-01 |
Hcw Biologics Inc |
Methods for activating regulatory t cells
|
CN116670163A
(zh)
|
2020-02-11 |
2023-08-29 |
Hcw生物科技公司 |
治疗年龄相关疾病和炎性疾病的方法
|
AU2021219720A1
(en)
|
2020-02-11 |
2022-08-04 |
HCW Biologics, Inc. |
Chromatography resin and uses thereof
|
TW202146452A
(zh)
|
2020-02-28 |
2021-12-16 |
瑞士商諾華公司 |
結合cd123和cd3之雙特異性抗體的給藥
|
US20230113705A1
(en)
|
2020-02-28 |
2023-04-13 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for diagnosing, prognosing and managing treatment of breast cancer
|
EP4110341A2
(en)
|
2020-02-28 |
2023-01-04 |
Novartis AG |
A triple pharmaceutical combination comprising dabrafenib, an erk inhibitor and a raf inhibitor
|
AU2021357520A1
(en)
|
2020-03-05 |
2022-09-29 |
Neotx Therapeutics Ltd. |
Methods and compositions for treating cancer with immune cells
|
IL296065A
(en)
|
2020-03-06 |
2022-10-01 |
Incyte Corp |
Combined treatment including axl/mer and pd-1/pd-l1 inhibitors
|
EP4114450A1
(en)
|
2020-03-06 |
2023-01-11 |
Stichting Het Nederlands Kanker Instituut- Antoni van Leeuwenhoek Ziekenhuis |
Modulating anti-tumor immunity
|
JP2023516724A
(ja)
|
2020-03-06 |
2023-04-20 |
オーエヌエー セラピューティクス エセ.エレ. |
抗cd36抗体及び癌を治療するためのそれらの使用
|
WO2021183318A2
(en)
|
2020-03-09 |
2021-09-16 |
President And Fellows Of Harvard College |
Methods and compositions relating to improved combination therapies
|
KR20230069042A
(ko)
|
2020-03-20 |
2023-05-18 |
오나 테라퓨틱스, 인코포레이티드 |
원형 rna 조성물 및 방법
|
PE20230821A1
(es)
|
2020-03-23 |
2023-05-19 |
Bristol Myers Squibb Co |
Anticuerpos anti-ccr8 para el tratamiento del cancer
|
TW202204339A
(zh)
|
2020-03-31 |
2022-02-01 |
美商施萬生物製藥研發 Ip有限責任公司 |
經取代的嘧啶及使用方法
|
WO2021207689A2
(en)
|
2020-04-10 |
2021-10-14 |
Juno Therapeutics, Inc. |
Methods and uses related to cell therapy engineered with a chimeric antigen receptor targeting b-cell maturation antigen
|
CN115698075A
(zh)
|
2020-04-14 |
2023-02-03 |
葛兰素史密斯克莱知识产权发展有限公司 |
涉及抗icos和抗pd1抗体,任选地进一步涉及抗tim3抗体的癌症的组合治疗
|
CA3171597A1
(en)
|
2020-04-14 |
2021-10-21 |
Glaxosmithkline Intellectual Property Development Limited |
Combination treatment for cancer
|
CR20220584A
(es)
|
2020-04-16 |
2023-02-15 |
Incyte Corp |
Inhibidores de kras tricíclicos fusionados
|
CA3180635A1
(en)
|
2020-04-21 |
2021-10-28 |
Novartis Ag |
Dosing regimen for treating a disease modulated by csf-1r
|
TW202206100A
(zh)
|
2020-04-27 |
2022-02-16 |
美商西健公司 |
癌症之治療
|
AU2021262794A1
(en)
|
2020-04-29 |
2022-11-24 |
HCW Biologics, Inc. |
Anti-CD26 proteins and uses thereof
|
US20230181756A1
(en)
|
2020-04-30 |
2023-06-15 |
Novartis Ag |
Ccr7 antibody drug conjugates for treating cancer
|
WO2021224186A1
(en)
|
2020-05-04 |
2021-11-11 |
Institut Curie |
New pyridine derivatives as radiosensitizers
|
JP2023526783A
(ja)
|
2020-05-05 |
2023-06-23 |
テオン セラピューティクス,インク. |
カンナビノイド受容体2型(cb2)調節物質及びその使用
|
TW202202493A
(zh)
|
2020-05-06 |
2022-01-16 |
美商默沙東藥廠 |
Il4i1抑制劑及使用方法
|
MX2022014191A
(es)
|
2020-05-13 |
2022-12-07 |
Massachusetts Inst Technology |
Composiciones de microdispositivos polimericos y su uso en la inmunoterapia de cancer.
|
US11739102B2
(en)
|
2020-05-13 |
2023-08-29 |
Incyte Corporation |
Fused pyrimidine compounds as KRAS inhibitors
|
US20230302050A1
(en)
|
2020-05-20 |
2023-09-28 |
Institut Curie |
Single Domain Antibodies and Their Use in Cancer Therapies
|
CA3184802A1
(en)
|
2020-05-26 |
2021-12-02 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Severe acute respiratory syndrome coronavirus 2 (sars-cov-2) polypeptides and uses thereof for vaccine purposes
|
CA3168738A1
(en)
|
2020-05-26 |
2021-12-02 |
Matthew G. Fury |
Methods of treating cervical cancer by administering a pd-1 inhibitor
|
US20230173095A1
(en)
|
2020-05-29 |
2023-06-08 |
President And Fellows Of Harvard College |
Living cells engineered with polyphenol-functionalized biologically active nanocomplexes
|
KR20230031280A
(ko)
|
2020-06-01 |
2023-03-07 |
에이치씨더블유 바이올로직스, 인크. |
노화 관련 장애의 치료 방법
|
WO2021247003A1
(en)
|
2020-06-01 |
2021-12-09 |
HCW Biologics, Inc. |
Methods of treating aging-related disorders
|
US11767353B2
(en)
|
2020-06-05 |
2023-09-26 |
Theraly Fibrosis, Inc. |
Trail compositions with reduced immunogenicity
|
WO2021253041A1
(en)
|
2020-06-10 |
2021-12-16 |
Theravance Biopharma R&D Ip, Llc |
Naphthyridine derivatives useful as alk5 inhibitors
|
AU2021288224A1
(en)
|
2020-06-11 |
2023-01-05 |
Novartis Ag |
ZBTB32 inhibitors and uses thereof
|
AR122644A1
(es)
|
2020-06-19 |
2022-09-28 |
Onxeo |
Nuevas moléculas de ácido nucleico conjugado y sus usos
|
AU2021297099A1
(en)
|
2020-06-23 |
2023-01-05 |
Novartis Ag |
Dosing regimen comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives
|
WO2021262969A1
(en)
|
2020-06-24 |
2021-12-30 |
The General Hospital Corporation |
Materials and methods of treating cancer
|
US20230293530A1
(en)
|
2020-06-24 |
2023-09-21 |
Yeda Research And Development Co. Ltd. |
Agents for sensitizing solid tumors to treatment
|
BR112022026090A2
(pt)
|
2020-06-25 |
2023-01-17 |
Celgene Corp |
Métodos para tratar câncer com terapias de combinação
|
CR20230025A
(es)
|
2020-06-26 |
2023-10-05 |
Amgen Inc |
Muteínas de il-10 y proteínas de fusión de las mismas referencia cruzada a solicitudes relacionadas
|
EP4172323A1
(en)
|
2020-06-29 |
2023-05-03 |
Flagship Pioneering Innovations V, Inc. |
Viruses engineered to promote thanotransmission and their use in treating cancer
|
US20230266322A1
(en)
|
2020-06-30 |
2023-08-24 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting the risk of recurrence and/or death of patients suffering from a solid cancer after preoperative adjuvant therapy and radical surgery
|
CN115997123A
(zh)
|
2020-06-30 |
2023-04-21 |
国家医疗保健研究所 |
用于预测实体癌患者在术前辅助治疗后复发和/或死亡风险的方法
|
IL298993A
(en)
|
2020-07-07 |
2023-02-01 |
BioNTech SE |
Therapeutic RNA for HPV positive cancer
|
IL299657A
(en)
|
2020-07-07 |
2023-03-01 |
Celgene Corp |
Pharmaceutical preparations including (S)-4-(4-(4-(((2-(2,6-DIOXOPIPERIDIN-3-YL)-1-OXOISOINDOLIN-4-YL)OXY)M ETHYL) BENZYL)PIPERAZIN-1 -YL)-3-FLUOROBENZONITRILE AND METHODS OF USING THEM
|
WO2022009157A1
(en)
|
2020-07-10 |
2022-01-13 |
Novartis Ag |
Lhc165 and spartalizumab combinations for treating solid tumors
|
JP2023535610A
(ja)
|
2020-07-28 |
2023-08-18 |
アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル |
ガンを予防及び処置するための方法及び組成物
|
EP4188549A1
(en)
|
2020-08-03 |
2023-06-07 |
Novartis AG |
Heteroaryl substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
MX2023002123A
(es)
|
2020-08-26 |
2023-03-15 |
Regeneron Pharma |
Metodos de tratamiento de cancer mediante la administracion de un inhibidor de pd-1.
|
GB2616354A
(en)
|
2020-08-26 |
2023-09-06 |
Marengo Therapeutics Inc |
Methods of detecting TRBC1 or TRBC2
|
MX2023002332A
(es)
|
2020-08-28 |
2023-03-21 |
Bristol Myers Squibb Co |
Terapia con antagonistas del gen 3 de activacion de linfocitos (lag-3) para carcinoma hepatocelular.
|
WO2022047093A1
(en)
|
2020-08-28 |
2022-03-03 |
Incyte Corporation |
Vinyl imidazole compounds as inhibitors of kras
|
EP4204021A1
(en)
|
2020-08-31 |
2023-07-05 |
Advanced Accelerator Applications International S.A. |
Method of treating psma-expressing cancers
|
JP2023538955A
(ja)
|
2020-08-31 |
2023-09-12 |
ブリストル-マイヤーズ スクイブ カンパニー |
細胞局在シグネチャーおよび免疫療法
|
WO2022043558A1
(en)
|
2020-08-31 |
2022-03-03 |
Advanced Accelerator Applications International Sa |
Method of treating psma-expressing cancers
|
US20230265196A1
(en)
|
2020-09-02 |
2023-08-24 |
Pharmabcine Inc. |
Combination Therapy of a PD-1 Antagonist and an Antagonist for VEGFR-2 for Treating Patients with Cancer
|
US11932692B2
(en)
|
2020-09-03 |
2024-03-19 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating cancer pain by administering a PD-1 inhibitor
|
WO2022072783A1
(en)
|
2020-10-02 |
2022-04-07 |
Incyte Corporation |
Bicyclic dione compounds as inhibitors of kras
|
EP4222171A1
(en)
|
2020-10-02 |
2023-08-09 |
Regeneron Pharmaceuticals, Inc. |
Combination of antibodies for treating cancer with reduced cytokine release syndrome
|
EP4225770A1
(en)
|
2020-10-05 |
2023-08-16 |
Bristol-Myers Squibb Company |
Methods for concentrating proteins
|
EP4229090A1
(en)
|
2020-10-16 |
2023-08-23 |
Université d'Aix-Marseille |
Anti-gpc4 single domain antibodies
|
WO2022084325A1
(en)
|
2020-10-20 |
2022-04-28 |
Institut Curie |
Metallic trans-(n-heterocyclic carbene)-amine-platinum complexes and uses thereof for treating cancer
|
WO2022084531A1
(en)
|
2020-10-23 |
2022-04-28 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating glioma
|
EP4232019A1
(en)
|
2020-10-23 |
2023-08-30 |
Bristol-Myers Squibb Company |
Lag-3 antagonist therapy for lung cancer
|
JP2023549678A
(ja)
|
2020-10-28 |
2023-11-29 |
イケナ オンコロジー, インコーポレイテッド |
AHR阻害剤のPDx阻害剤またはドキソルビシンとの組み合わせ
|
EP4209216A1
(en)
|
2020-10-28 |
2023-07-12 |
Eisai R&D Management Co., Ltd |
Pharmaceutical composition for treating tumors
|
US11780836B2
(en)
|
2020-11-06 |
2023-10-10 |
Incyte Corporation |
Process of preparing a PD-1/PD-L1 inhibitor
|
KR20230117573A
(ko)
|
2020-11-06 |
2023-08-08 |
인사이트 코포레이션 |
Pd-1 및 pd-l1 억제제, 및 이의 염 및 결정형의 제조 방법
|
US20240025993A1
(en)
|
2020-11-06 |
2024-01-25 |
Novartis Ag |
Cd19 binding molecules and uses thereof
|
US11760756B2
(en)
|
2020-11-06 |
2023-09-19 |
Incyte Corporation |
Crystalline form of a PD-1/PD-L1 inhibitor
|
WO2022098972A1
(en)
|
2020-11-08 |
2022-05-12 |
Seagen Inc. |
Combination-therapy antibody drug conjugate with immune cell inhibitor
|
WO2022101302A1
(en)
|
2020-11-12 |
2022-05-19 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Antibodies conjugated or fused to the receptor-binding domain of the sars-cov-2 spike protein and uses thereof for vaccine purposes
|
WO2022101463A1
(en)
|
2020-11-16 |
2022-05-19 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of the last c-terminal residues m31/41 of zikv m ectodomain for triggering apoptotic cell death
|
WO2022101481A1
(en)
|
2020-11-16 |
2022-05-19 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for predicting and treating uveal melanoma
|
WO2022101484A1
(en)
|
2020-11-16 |
2022-05-19 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for predicting and treating uveal melanoma
|
US20230416196A1
(en)
|
2020-11-18 |
2023-12-28 |
Institut Curie |
Dimer of biguanidines and their therapeutic uses
|
TW202227089A
(zh)
|
2020-11-30 |
2022-07-16 |
大陸商杭州阿諾生物醫藥科技有限公司 |
用於治療pik3ca突變癌症的組合療法
|
WO2022120179A1
(en)
|
2020-12-03 |
2022-06-09 |
Bristol-Myers Squibb Company |
Multi-tumor gene signatures and uses thereof
|
US20220218614A1
(en)
|
2020-12-04 |
2022-07-14 |
Tidal Therapeutics, Inc. |
Ionizable cationic lipids and lipid nanoparticles, and methods of synthesis and use thereof
|
CA3204091A1
(en)
|
2020-12-08 |
2022-06-16 |
Infinity Pharmaceuticals, Inc. |
Eganelisib for use in the treatment of pd-l1 negative cancer
|
TW202237119A
(zh)
|
2020-12-10 |
2022-10-01 |
美商住友製藥腫瘤公司 |
Alk﹘5抑制劑和彼之用途
|
WO2022130206A1
(en)
|
2020-12-16 |
2022-06-23 |
Pfizer Inc. |
TGFβr1 INHIBITOR COMBINATION THERAPIES
|
IL301701A
(en)
|
2020-12-18 |
2023-05-01 |
Lamkap Bio Beta Ag |
Bispecific antibodies against CEACAM5 and CD47
|
WO2022135667A1
(en)
|
2020-12-21 |
2022-06-30 |
BioNTech SE |
Therapeutic rna for treating cancer
|
WO2022135666A1
(en)
|
2020-12-21 |
2022-06-30 |
BioNTech SE |
Treatment schedule for cytokine proteins
|
TW202245808A
(zh)
|
2020-12-21 |
2022-12-01 |
德商拜恩迪克公司 |
用於治療癌症之治療性rna
|
EP4267172A1
(en)
|
2020-12-28 |
2023-11-01 |
Bristol-Myers Squibb Company |
Subcutaneous administration of pd1/pd-l1 antibodies
|
CA3201348A1
(en)
|
2020-12-28 |
2022-07-07 |
Masano HUANG |
Antibody compositions and methods of use thereof
|
TW202241441A
(zh)
|
2020-12-29 |
2022-11-01 |
美商英塞特公司 |
包含a2a/a2b抑制劑、pd-1/pd-l1抑制劑及抗cd73抗體之組合療法
|
CA3204162A1
(en)
|
2021-01-11 |
2022-07-14 |
Robert Kastelein |
Compositions and methods related to receptor pairing
|
WO2022152862A1
(en)
|
2021-01-14 |
2022-07-21 |
Institut Curie |
Her2 single domain antibodies variants and cars thereof
|
EP4284510A1
(en)
|
2021-01-29 |
2023-12-06 |
Novartis AG |
Dosage regimes for anti-cd73 and anti-entpd2 antibodies and uses thereof
|
EP4284919A1
(en)
|
2021-01-29 |
2023-12-06 |
Iovance Biotherapeutics, Inc. |
Methods of making modified tumor infiltrating lymphocytes and their use in adoptive cell therapy
|
WO2022165403A1
(en)
|
2021-02-01 |
2022-08-04 |
Yale University |
Chemotherapeutic bioadhesive particles with immunostimulatory molecules for cancer treatment
|
WO2022171121A1
(zh)
|
2021-02-10 |
2022-08-18 |
同润生物医药(上海)有限公司 |
治疗肿瘤的方法和组合
|
EP4291243A1
(en)
|
2021-02-12 |
2023-12-20 |
Synthorx, Inc. |
Lung cancer combination therapy with il-2 conjugates and an anti-pd-1 antibody or antigen-binding fragment thereof
|
WO2022185160A1
(en)
|
2021-03-02 |
2022-09-09 |
Glaxosmithkline Intellectual Property Development Limited |
Substituted pyridines as dnmt1 inhibitors
|
US20240092942A1
(en)
|
2021-03-05 |
2024-03-21 |
Leadartis, S.L. |
Trimeric polypeptides and uses thereof in the treatment of cancer
|
WO2022189618A1
(en)
|
2021-03-12 |
2022-09-15 |
Institut Curie |
Nitrogen-containing heterocycles as radiosensitizers
|
EP4308118A1
(en)
|
2021-03-17 |
2024-01-24 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Methods and compositions for treating melanoma
|
JP2024511373A
(ja)
|
2021-03-18 |
2024-03-13 |
ノバルティス アーゲー |
がんのためのバイオマーカーおよびその使用
|
BR112023018950A2
(pt)
|
2021-03-19 |
2024-02-27 |
Icahn School Med Mount Sinai |
Composto, composições nanobiológica e farmacêutica, métodos para tratar um distúrbio de proliferação celular, para tratar sepse e para ativar um receptor nod2, processo para fabricação de uma composição nanobiológica e kit
|
IL305776A
(en)
|
2021-03-23 |
2023-11-01 |
Regeneron Pharma |
Methods of treating cancer in patients with suppression or failure of the immune system through the administration of a PD-1 inhibitor
|
TW202304506A
(zh)
|
2021-03-25 |
2023-02-01 |
日商安斯泰來製藥公司 |
涉及抗claudin 18.2抗體的組合治療以治療癌症
|
KR20240005700A
(ko)
|
2021-03-29 |
2024-01-12 |
주노 쎄러퓨티크스 인코퍼레이티드 |
체크포인트 억제제 요법 및 car t 세포 요법의 조합을 사용한 투여 및 치료 방법
|
EP4314060A1
(en)
|
2021-03-31 |
2024-02-07 |
GlaxoSmithKline Intellectual Property Development Limited |
Antigen binding proteins and combinations thereof
|
JP2024512669A
(ja)
|
2021-03-31 |
2024-03-19 |
フラグシップ パイオニアリング イノベーションズ ブイ,インコーポレーテッド |
タノトランスミッションポリペプチド及び癌の処置におけるそれらの使用
|
EP4314068A1
(en)
|
2021-04-02 |
2024-02-07 |
The Regents Of The University Of California |
Antibodies against cleaved cdcp1 and uses thereof
|
TW202304979A
(zh)
|
2021-04-07 |
2023-02-01 |
瑞士商諾華公司 |
抗TGFβ抗體及其他治療劑用於治療增殖性疾病之用途
|
WO2022216993A2
(en)
|
2021-04-08 |
2022-10-13 |
Marengo Therapeutics, Inc. |
Multifuntional molecules binding to tcr and uses thereof
|
CA3214729A1
(en)
|
2021-04-08 |
2022-10-13 |
Marilena GALLOTTA |
Combination therapies with cbl-b inhibitor compounds
|
JP2024514816A
(ja)
|
2021-04-09 |
2024-04-03 |
シージェン インコーポレイテッド |
抗tigit抗体を用いるがんの治療方法
|
CA3215903A1
(en)
|
2021-04-12 |
2022-10-20 |
Incyte Corporation |
Combination therapy comprising an fgfr inhibitor and a nectin-4 targeting agent
|
AU2022257621A1
(en)
|
2021-04-13 |
2023-11-23 |
Nuvalent, Inc. |
Amino-substituted heterocycles for treating cancers with egfr mutations
|
WO2022219080A1
(en)
|
2021-04-14 |
2022-10-20 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
New method to improve nk cells cytotoxicity
|
WO2022221720A1
(en)
|
2021-04-16 |
2022-10-20 |
Novartis Ag |
Antibody drug conjugates and methods for making thereof
|
CA3212610A1
(en)
|
2021-04-20 |
2022-10-27 |
Philip MOQUIST |
Modulation of antibody-dependent cellular cytotoxicity
|
EP4326903A1
(en)
|
2021-04-23 |
2024-02-28 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Methods and compositions for treating cell senescence accumulation related disease
|
WO2022227015A1
(en)
|
2021-04-30 |
2022-11-03 |
Merck Sharp & Dohme Corp. |
Il4i1 inhibitors and methods of use
|
WO2022238386A1
(en)
|
2021-05-10 |
2022-11-17 |
Institut Curie |
Methods for the treatment of cancer, inflammatory diseases and autoimmune diseases
|
JPWO2022239820A1
(pt)
|
2021-05-13 |
2022-11-17 |
|
|
AR125874A1
(es)
|
2021-05-18 |
2023-08-23 |
Novartis Ag |
Terapias de combinación
|
CN117396222A
(zh)
|
2021-05-21 |
2024-01-12 |
天津立博美华基因科技有限责任公司 |
药物组合及其用途
|
WO2022251359A1
(en)
|
2021-05-26 |
2022-12-01 |
Theravance Biopharma R&D Ip, Llc |
Bicyclic inhibitors of alk5 and methods of use
|
TW202307210A
(zh)
|
2021-06-01 |
2023-02-16 |
瑞士商諾華公司 |
Cd19和cd22嵌合抗原受體及其用途
|
TW202313679A
(zh)
|
2021-06-03 |
2023-04-01 |
美商欣爍克斯公司 |
包含il-2接合物及pd-1拮抗劑之頭頸癌組合療法
|
GB202107994D0
(en)
|
2021-06-04 |
2021-07-21 |
Kymab Ltd |
Treatment of cancer
|
CA3218590A1
(en)
|
2021-06-07 |
2022-12-15 |
Providence Health & Services - Oregon |
Cxcr5, pd-1, and icos expressing tumor reactive cd4 t cells and their use
|
TW202313610A
(zh)
|
2021-06-09 |
2023-04-01 |
美商英塞特公司 |
作為fgfr抑制劑之三環雜環
|
CA3220274A1
(en)
|
2021-06-09 |
2022-12-15 |
Incyte Corporation |
Tricyclic heterocycles as fgfr inhibitors
|
AU2022303363A1
(en)
|
2021-06-29 |
2024-01-18 |
Flagship Pioneering Innovations V, Inc. |
Immune cells engineered to promote thanotransmission and uses thereof
|
WO2023280790A1
(en)
|
2021-07-05 |
2023-01-12 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Gene signatures for predicting survival time in patients suffering from renal cell carcinoma
|
WO2023283213A1
(en)
|
2021-07-07 |
2023-01-12 |
Incyte Corporation |
Tricyclic compounds as inhibitors of kras
|
WO2023285552A1
(en)
|
2021-07-13 |
2023-01-19 |
BioNTech SE |
Multispecific binding agents against cd40 and cd137 in combination therapy for cancer
|
WO2023287896A1
(en)
|
2021-07-14 |
2023-01-19 |
Incyte Corporation |
Tricyclic compounds as inhibitors of kras
|
US20230139492A1
(en)
|
2021-07-19 |
2023-05-04 |
Regeneron Pharmaceuticals, Inc. |
Combination of checkpoint inhibitors and an oncolytic virus for treating cancer
|
AU2022320051A1
(en)
|
2021-07-30 |
2024-01-25 |
ONA Therapeutics S.L. |
Anti-cd36 antibodies and their use to treat cancer
|
WO2023010080A1
(en)
|
2021-07-30 |
2023-02-02 |
Seagen Inc. |
Treatment for cancer
|
WO2023012147A1
(en)
|
2021-08-03 |
2023-02-09 |
F. Hoffmann-La Roche Ag |
Bispecific antibodies and methods of use
|
WO2023015198A1
(en)
|
2021-08-04 |
2023-02-09 |
Genentech, Inc. |
Il15/il15r alpha heterodimeric fc-fusion proteins for the expansion of nk cells in the treatment of solid tumours
|
WO2023011879A1
(en)
|
2021-08-05 |
2023-02-09 |
Institut Curie |
Scanning dynamic device for minibeams production
|
CA3229448A1
(en)
|
2021-08-23 |
2023-03-02 |
Immunitas Therapeutics, Inc. |
Anti-cd161 antibodies and uses thereof
|
WO2023034290A1
(en)
|
2021-08-31 |
2023-03-09 |
Incyte Corporation |
Naphthyridine compounds as inhibitors of kras
|
TW202325306A
(zh)
|
2021-09-02 |
2023-07-01 |
美商天恩治療有限公司 |
改良免疫細胞之生長及功能的方法
|
CA3231180A1
(en)
|
2021-09-08 |
2023-03-16 |
Redona Therapeutics, Inc. |
Papd5 and/or papd7 inhibiting 4-oxo-1,4-dihydroquinoline-3-carboxylic acid derivatives
|
WO2023039243A2
(en)
*
|
2021-09-13 |
2023-03-16 |
Achelois Biopharma, Inc. |
Hepatitis b virus antivirus (hbv-antivirus) compositions and methods of use
|
WO2023041744A1
(en)
|
2021-09-17 |
2023-03-23 |
Institut Curie |
Bet inhibitors for treating pab1 deficient cancer
|
US20230151005A1
(en)
|
2021-09-21 |
2023-05-18 |
Incyte Corporation |
Hetero-tricyclic compounds as inhibitors of kras
|
WO2023051926A1
(en)
|
2021-09-30 |
2023-04-06 |
BioNTech SE |
Treatment involving non-immunogenic rna for antigen vaccination and pd-1 axis binding antagonists
|
US20230143938A1
(en)
|
2021-10-01 |
2023-05-11 |
Incyte Corporation |
Pyrazoloquinoline kras inhibitors
|
WO2023057882A1
(en)
|
2021-10-05 |
2023-04-13 |
Pfizer Inc. |
Combinations of azalactam compounds with a pd-1 axis binding antagonist for the treatment of cancer
|
WO2023057534A1
(en)
|
2021-10-06 |
2023-04-13 |
Genmab A/S |
Multispecific binding agents against pd-l1 and cd137 in combination
|
TW202333802A
(zh)
|
2021-10-11 |
2023-09-01 |
德商拜恩迪克公司 |
用於肺癌之治療性rna(二)
|
US11939328B2
(en)
|
2021-10-14 |
2024-03-26 |
Incyte Corporation |
Quinoline compounds as inhibitors of KRAS
|
WO2023077034A1
(en)
|
2021-10-28 |
2023-05-04 |
Lyell Immunopharma, Inc. |
Methods for culturing immune cells
|
CA3224890A1
(en)
|
2021-10-29 |
2023-05-04 |
Bristol-Myers Squibb Company |
Lag-3 antagonist therapy for hematological cancer
|
WO2023081730A1
(en)
|
2021-11-03 |
2023-05-11 |
Teon Therapeutics, Inc. |
4-hydroxy-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide derivatives as cannabinoid cb2 receptor modulators for the treatment of cancer
|
WO2023078900A1
(en)
|
2021-11-03 |
2023-05-11 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating triple negative breast cancer (tnbc)
|
WO2023079428A1
(en)
|
2021-11-03 |
2023-05-11 |
Pfizer Inc. |
Combination therapies using tlr7/8 agonist
|
WO2023083439A1
(en)
|
2021-11-09 |
2023-05-19 |
BioNTech SE |
Tlr7 agonist and combinations for cancer treatment
|
TW202334223A
(zh)
*
|
2021-11-11 |
2023-09-01 |
美商再生元醫藥公司 |
Cd20-pd1結合分子及其使用方法
|
TW202319073A
(zh)
|
2021-11-12 |
2023-05-16 |
瑞士商諾華公司 |
用於治療肺癌的組合療法
|
WO2023088968A1
(en)
|
2021-11-17 |
2023-05-25 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Universal sarbecovirus vaccines
|
WO2023089032A1
(en)
|
2021-11-19 |
2023-05-25 |
Institut Curie |
Methods for the treatment of hrd cancer and brca-associated cancer
|
US20230226040A1
(en)
|
2021-11-22 |
2023-07-20 |
Incyte Corporation |
Combination therapy comprising an fgfr inhibitor and a kras inhibitor
|
WO2023097211A1
(en)
|
2021-11-24 |
2023-06-01 |
The University Of Southern California |
Methods for enhancing immune checkpoint inhibitor therapy
|
US20230203010A1
(en)
|
2021-12-03 |
2023-06-29 |
Incyte Corporation |
Bicyclic amine cdk12 inhibitors
|
WO2023099763A1
(en)
|
2021-12-03 |
2023-06-08 |
Institut Curie |
Sirt6 inhibitors for use in treating resistant hrd cancer
|
WO2023107705A1
(en)
|
2021-12-10 |
2023-06-15 |
Incyte Corporation |
Bicyclic amines as cdk12 inhibitors
|
WO2023111203A1
(en)
|
2021-12-16 |
2023-06-22 |
Onxeo |
New conjugated nucleic acid molecules and their uses
|
WO2023122573A1
(en)
|
2021-12-20 |
2023-06-29 |
Synthorx, Inc. |
Head and neck cancer combination therapy comprising an il-2 conjugate and pembrolizumab
|
WO2023118165A1
(en)
|
2021-12-21 |
2023-06-29 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treating melanoma
|
AR128043A1
(es)
|
2021-12-22 |
2024-03-20 |
Incyte Corp |
Sales y formas sólidas de un inhibidor de fgfr y procesos para su preparación
|
WO2023130081A1
(en)
|
2021-12-30 |
2023-07-06 |
Neoimmunetech, Inc. |
Method of treating a tumor with a combination of il-7 protein and vegf antagonist
|
WO2023133424A2
(en)
*
|
2022-01-05 |
2023-07-13 |
TCR2 Therapeutics Inc. |
Compositions and methods for tcr reprogramming using fusion proteins and anti-pd-1 fusion peptides
|
US20230312718A1
(en)
|
2022-01-07 |
2023-10-05 |
Regeneron Pharmaceuticals, Inc |
Methods of Treating Recurrent Ovarian Cancer with Bispecific Anti-MUC16 x Anti-CD3 Antibodies Alone or in Combination with Anti-PD-1 Antibodies
|
WO2023147371A1
(en)
|
2022-01-26 |
2023-08-03 |
Bristol-Myers Squibb Company |
Combination therapy for hepatocellular carcinoma
|
WO2023147488A1
(en)
|
2022-01-28 |
2023-08-03 |
Iovance Biotherapeutics, Inc. |
Cytokine associated tumor infiltrating lymphocytes compositions and methods
|
TW202342474A
(zh)
|
2022-02-14 |
2023-11-01 |
美商基利科學股份有限公司 |
抗病毒吡唑并吡啶酮化合物
|
WO2023154799A1
(en)
|
2022-02-14 |
2023-08-17 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Combination immunotherapy for treating cancer
|
WO2023159102A1
(en)
|
2022-02-17 |
2023-08-24 |
Regeneron Pharmaceuticals, Inc. |
Combinations of checkpoint inhibitors and oncolytic virus for treating cancer
|
US20230277669A1
(en)
|
2022-02-24 |
2023-09-07 |
Amazentis Sa |
Uses of urolithins
|
WO2023164638A1
(en)
|
2022-02-25 |
2023-08-31 |
Bristol-Myers Squibb Company |
Combination therapy for colorectal carcinoma
|
WO2023168363A1
(en)
|
2022-03-02 |
2023-09-07 |
HCW Biologics, Inc. |
Method of treating pancreatic cancer
|
WO2023168404A1
(en)
|
2022-03-04 |
2023-09-07 |
Bristol-Myers Squibb Company |
Methods of treating a tumor
|
US20230279004A1
(en)
|
2022-03-07 |
2023-09-07 |
Incyte Corporation |
Solid forms, salts, and processes of preparation of a cdk2 inhibitor
|
WO2023170606A1
(en)
|
2022-03-08 |
2023-09-14 |
Alentis Therapeutics Ag |
Use of anti-claudin-1 antibodies to increase t cell availability
|
WO2023177772A1
(en)
|
2022-03-17 |
2023-09-21 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating recurrent epithelioid sarcoma with bispecific anti-muc16 x anti-cd3 antibodies alone or in combination with anti-pd-1 antibodies
|
WO2023178329A1
(en)
|
2022-03-18 |
2023-09-21 |
Bristol-Myers Squibb Company |
Methods of isolating polypeptides
|
WO2023180552A1
(en)
|
2022-03-24 |
2023-09-28 |
Institut Curie |
Immunotherapy targeting tumor transposable element derived neoantigenic peptides in glioblastoma
|
WO2023187024A1
(en)
|
2022-03-31 |
2023-10-05 |
Institut Curie |
Modified rela protein for inducing interferon expression and engineered immune cells with improved interferon expression
|
WO2023192478A1
(en)
|
2022-04-01 |
2023-10-05 |
Bristol-Myers Squibb Company |
Combination therapy with anti-il-8 antibodies and anti-pd-1 antibodies for treating cancer
|
WO2023196987A1
(en)
|
2022-04-07 |
2023-10-12 |
Bristol-Myers Squibb Company |
Methods of treating tumor
|
WO2023194608A1
(en)
|
2022-04-07 |
2023-10-12 |
Institut Curie |
Myeloid cells modified by chimeric antigen receptor and uses thereof for anti-cancer therapy
|
WO2023194607A1
(en)
|
2022-04-07 |
2023-10-12 |
Institut Curie |
Myeloid cells modified by chimeric antigen receptor with cd40 and uses thereof for anti-cancer therapy
|
US20230326022A1
(en)
|
2022-04-08 |
2023-10-12 |
Bristol-Myers Squibb Company |
Machine Learning Identification, Classification, and Quantification of Tertiary Lymphoid Structures
|
WO2023213763A1
(en)
|
2022-05-02 |
2023-11-09 |
Transgene |
Poxvirus encoding a binding agent comprising an anti- pd-l1 sdab
|
WO2023213764A1
(en)
|
2022-05-02 |
2023-11-09 |
Transgene |
Fusion polypeptide comprising an anti-pd-l1 sdab and a member of the tnfsf
|
WO2023214325A1
(en)
|
2022-05-05 |
2023-11-09 |
Novartis Ag |
Pyrazolopyrimidine derivatives and uses thereof as tet2 inhibitors
|
WO2023218046A1
(en)
|
2022-05-12 |
2023-11-16 |
Genmab A/S |
Binding agents capable of binding to cd27 in combination therapy
|
WO2023224912A1
(en)
|
2022-05-16 |
2023-11-23 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating metastatic castration-resistant prostate cancer with bispecific anti-psma x anti-cd3 antibodies alone or in combination with anti-pd-1 antibodies
|
WO2023230554A1
(en)
|
2022-05-25 |
2023-11-30 |
Pfizer Inc. |
Combination of a braf inhibitor, an egfr inhibitor, and a pd-1 antagonist for the treatment of braf v600e-mutant, msi-h/dmmr colorectal cancer
|
WO2023227949A1
(en)
|
2022-05-27 |
2023-11-30 |
Takeda Pharmaceutical Company Limited |
Dosing of cd38-binding fusion protein
|
WO2023230541A1
(en)
|
2022-05-27 |
2023-11-30 |
Viiv Healthcare Company |
Piperazine derivatives useful in hiv therapy
|
WO2023235847A1
(en)
|
2022-06-02 |
2023-12-07 |
Bristol-Myers Squibb Company |
Antibody compositions and methods of use thereof
|
WO2023240156A1
(en)
|
2022-06-08 |
2023-12-14 |
Tidal Therapeutics, Inc. |
Ionizable cationic lipids and lipid nanoparticles, and methods of synthesis and use thereof
|
TW202402279A
(zh)
|
2022-06-08 |
2024-01-16 |
美商英塞特公司 |
作為dgk抑制劑之三環三唑并化合物
|
WO2023242351A1
(en)
|
2022-06-16 |
2023-12-21 |
Lamkap Bio Beta Ag |
Combination therapy of bispecific antibodies against ceacam5 and cd47 and bispecific antibodies against ceacam5 and cd3
|
WO2023250400A1
(en)
|
2022-06-22 |
2023-12-28 |
Juno Therapeutics, Inc. |
Treatment methods for second line therapy of cd19-targeted car t cells
|
WO2023250430A1
(en)
|
2022-06-22 |
2023-12-28 |
Incyte Corporation |
Bicyclic amine cdk12 inhibitors
|
WO2024003353A1
(en)
|
2022-07-01 |
2024-01-04 |
Transgene |
Fusion protein comprising a surfactant-protein-d and a member of the tnfsf
|
US20240101557A1
(en)
|
2022-07-11 |
2024-03-28 |
Incyte Corporation |
Fused tricyclic compounds as inhibitors of kras g12v mutants
|
WO2024015372A1
(en)
|
2022-07-14 |
2024-01-18 |
Teon Therapeutics, Inc. |
Adenosine receptor antagonists and uses thereof
|
EP4310197A1
(en)
|
2022-07-21 |
2024-01-24 |
Fundación para la Investigación Biomédica del Hospital Universitario Puerta de Hierro Majadahonda |
Method for identifying lung cancer patients for a combination treatment of immuno- and chemotherapy
|
WO2024030453A1
(en)
|
2022-08-02 |
2024-02-08 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating metastatic castration-resistant prostate cancer with bispecific anti-psma x anti-cd28 antibodies in combination with anti-pd-1 antibodies
|
US20240041929A1
(en)
|
2022-08-05 |
2024-02-08 |
Juno Therapeutics, Inc. |
Chimeric antigen receptors specific for gprc5d and bcma
|
WO2024033400A1
(en)
|
2022-08-10 |
2024-02-15 |
Institut National de la Santé et de la Recherche Médicale |
Sk2 inhibitor for the treatment of pancreatic cancer
|
WO2024033399A1
(en)
|
2022-08-10 |
2024-02-15 |
Institut National de la Santé et de la Recherche Médicale |
Sigmar1 ligand for the treatment of pancreatic cancer
|
WO2024040175A1
(en)
|
2022-08-18 |
2024-02-22 |
Pulmatrix Operating Company, Inc. |
Methods for treating cancer using inhaled angiogenesis inhibitor
|
WO2024040264A1
(en)
|
2022-08-19 |
2024-02-22 |
Massachusetts Institute Of Technology |
Compositions and methods for targeting dendritic cell lectins
|
WO2024052356A1
(en)
|
2022-09-06 |
2024-03-14 |
Institut National de la Santé et de la Recherche Médicale |
Inhibitors of the ceramide metabolic pathway for overcoming immunotherapy resistance in cancer
|
WO2024056716A1
(en)
|
2022-09-14 |
2024-03-21 |
Institut National de la Santé et de la Recherche Médicale |
Methods and pharmaceutical compositions for the treatment of dilated cardiomyopathy
|
WO2024068617A1
(en)
|
2022-09-26 |
2024-04-04 |
Institut Curie |
Myeloid cells expressing il-2 and uses thereof for quick anticancer therapy
|
WO2024069009A1
(en)
|
2022-09-30 |
2024-04-04 |
Alentis Therapeutics Ag |
Treatment of drug-resistant hepatocellular carcinoma
|