WO2018215937A1 - Interleukin-7 antibody cytokine engrafted proteins and methods of use in the treatment of cancer - Google Patents

Interleukin-7 antibody cytokine engrafted proteins and methods of use in the treatment of cancer Download PDF

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Publication number
WO2018215937A1
WO2018215937A1 PCT/IB2018/053624 IB2018053624W WO2018215937A1 WO 2018215937 A1 WO2018215937 A1 WO 2018215937A1 IB 2018053624 W IB2018053624 W IB 2018053624W WO 2018215937 A1 WO2018215937 A1 WO 2018215937A1
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WO
WIPO (PCT)
Prior art keywords
seq id
antibody
cytokine engrafted
variable region
chain variable
Prior art date
Application number
PCT/IB2018/053624
Other languages
French (fr)
Inventor
Michael DIDONATO
Rodrigo Andreas HESS
Glen Spraggon
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Priority to US201762510547P priority Critical
Priority to US62/510,547 priority
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of WO2018215937A1 publication Critical patent/WO2018215937A1/en

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